Hub : Genes

Prdx5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability Prdx5 0.03 0.02 4.6e-03 0 0 -0 0 1.8e-01 7.4e-02 4.2e-01 2.4e-01
2 Brain mRNA stability Prdx5 0.06 0.04 3.8e-06 0.07 0.04 0.04 0.05 7.5e-07 5.5e-05 5.2e-05 2.0e-05
3 PL gene expression Prdx5 0.37 0.1 0.0e+00 0.43 0.42 0.47 0.47 6.1e-52 1.4e-50 4.5e-57 2.0e-57
4 BLA gene expression Prdx5 0.43 0.13 0.0e+00 0.43 0.38 0.4 0.41 7.8e-25 3.6e-21 1.8e-22 1.0e-23
5 OFC gene expression Prdx5 0.48 0.16 4.0e-10 0.33 0.31 0.34 0.35 1.2e-08 3.4e-08 5.2e-09 4.5e-09
6 IL gene expression Prdx5 0.48 0.15 3.6e-10 0.33 0.33 0.33 0.32 1.1e-08 9.7e-09 9.4e-09 1.9e-08
7 LHb gene expression Prdx5 0.27 0.14 1.4e-04 0.16 0.11 0.1 0.12 1.2e-04 1.5e-03 2.0e-03 1.0e-03
8 NAcc gene expression Prdx5 0.17 0.07 0.0e+00 0.2 0.17 0.17 0.19 2.5e-22 2.0e-19 2.0e-19 4.8e-21
9 Brain alternative TSS NM_053610.1 0.06 0.04 1.6e-06 0.06 0.06 0.05 0.06 5.4e-06 5.1e-06 1.4e-05 5.6e-06
10 Adipose gene expression Prdx5 0.21 0.09 0.0e+00 0.13 0.15 0.14 0.14 1.7e-14 4.2e-16 2.4e-15 4.6e-15
11 Brain alternative TSS XM_039105128.1 0.06 0.03 3.4e-06 0.06 0.05 0.05 0.06 3.7e-06 9.7e-06 2.5e-05 7.6e-06
12 PL mRNA stability Prdx5 0.05 0.03 2.1e-05 0.04 0.04 0.04 0.04 2.3e-05 4.5e-05 1.6e-05 3.5e-05
13 BLA alternative TSS NM_053610.1 0.08 0.05 2.6e-03 0.01 0.01 0 0.01 6.2e-02 5.1e-02 1.7e-01 1.1e-01
14 Liver alternative TSS XM_039105162.1 0.36 0.11 0.0e+00 0.26 0.27 0.28 0.27 8.7e-29 2.7e-30 1.2e-30 1.2e-29
15 PL alternative TSS XM_039105128.1 0.11 0.07 7.6e-09 0.04 0.08 0.08 0.08 1.8e-05 2.3e-09 4.1e-09 5.2e-09
16 Liver mRNA stability Prdx5 0.27 0.11 0.0e+00 0.17 0.16 0.16 0.16 4.7e-18 1.7e-17 5.5e-18 9.2e-18
17 pVTA gene expression Prdx5 0.13 0.07 9.6e-05 0.02 0.06 0.03 0.04 4.2e-02 1.4e-03 1.8e-02 1.2e-02
18 PL alternative TSS NM_053610.1 0.09 0.06 2.1e-07 0.03 0.06 0.06 0.06 2.4e-04 1.0e-07 3.2e-07 5.3e-07
19 Brain gene expression Prdx5 0.39 0.16 0.0e+00 0.31 0.29 0.31 0.31 9.3e-30 1.3e-27 1.5e-29 1.1e-29
20 Liver gene expression Prdx5 0.6 0.1 0.0e+00 0.45 0.47 0.48 0.47 7.2e-55 5.2e-59 8.9e-60 6.4e-59
21 Liver alternative TSS XM_039105248.1 0.05 0.03 8.0e-04 0 0.01 -0 0.01 2.0e-01 2.0e-02 4.3e-01 6.3e-02
22 Liver isoform ratio XM_039105162.1 0.12 0.07 2.2e-10 0.07 0.06 0.07 0.06 7.6e-08 4.2e-07 4.3e-08 2.8e-07
23 Liver alternative TSS XM_039105128.1 0.39 0.11 0.0e+00 0.3 0.3 0.31 0.3 1.7e-33 2.7e-34 2.7e-35 7.9e-34
24 Liver alternative TSS XM_039105128.1 0.38 0.11 0.0e+00 0.29 0.29 0.3 0.29 3.8e-32 2.4e-32 4.6e-34 1.6e-32
25 IL isoform ratio XM_039105128.1 0.18 0.12 9.9e-03 0.03 0 -0 0.01 6.8e-02 2.4e-01 4.0e-01 1.8e-01
26 Liver isoform ratio NM_053610.1 0.17 0.12 1.8e-09 0.04 0.06 0.07 0.06 1.0e-05 4.5e-07 3.0e-08 9.6e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26
Bone: apparent density0.50.82.3-0.7-0.80.7-0.80.8-1.4-0.7-0.70.8-1.00.8-0.81.50.7-1.50.51.31.5-0.90.50.30.4-0.4-0.80.51.0
Area under the delay curve0.10.10.50.2-0.0-0.2-0.1-0.20.1-0.1-0.10.10.20.0-0.10.20.3-0.00.10.5-0.00.00.30.00.3-0.4-0.6-0.6-0.7
BMI with tail2.99.420.7-2.4-3.02.6-2.92.6-4.0-3.1-3.13.1-2.92.7-2.64.43.2-4.02.64.53.9-3.52.6-0.62.5-1.7-3.20.13.4
BMI without tail1.93.98.0-1.4-2.11.5-2.11.4-2.1-2.2-2.22.1-1.41.7-2.62.32.2-1.81.92.81.7-2.31.9-1.11.9-1.3-2.1-0.62.7
Body weight3.615.224.5-3.7-4.14.0-4.14.0-4.7-4.2-4.24.3-3.84.0-3.04.54.4-4.23.94.93.8-4.93.8-2.53.8-3.3-4.20.30.7
Weight adjusted by age2.22.53.8-1.9-1.71.8-1.71.8-1.9-1.9-1.91.7-2.01.5-1.11.81.6-1.81.41.51.7-1.31.3-1.11.1-1.0-1.21.0-0.7
Bone surface4.57.915.8-3.0-2.83.1-2.83.2-3.7-2.7-2.72.8-3.52.8-3.03.92.7-3.91.93.14.0-2.91.7-0.51.6-1.5-2.12.21.0
Bone volume1.93.29.4-1.9-1.61.8-1.62.0-2.5-1.5-1.51.5-2.41.6-1.62.81.4-2.90.81.93.1-1.70.60.40.4-0.4-0.92.21.2
Breakpoint value in progressive ratio session2.83.15.0-2.2-2.12.1-2.02.1-1.9-1.8-1.82.0-2.21.9-1.62.01.8-1.91.61.61.9-1.91.4-1.31.3-1.3-1.21.2-0.7
Number of licking bursts0.20.30.5-0.7-0.50.6-0.50.7-0.6-0.5-0.50.5-0.70.7-0.60.60.6-0.60.30.40.6-0.50.3-0.30.3-0.3-0.40.5-0.4
Context. condit. distance diff. score1.51.83.11.61.3-1.71.3-1.81.61.51.5-1.41.6-1.61.3-1.2-1.41.2-1.2-1.0-1.21.2-1.11.0-1.11.31.1-0.90.8
Locomotion velocity, session 10.20.21.10.3-0.1-0.10.1-0.00.0-0.1-0.10.10.40.1-0.5-0.00.30.20.60.5-0.30.10.5-0.20.6-0.6-0.6-1.00.6
Locomotion distance, session 10.40.51.6-0.2-0.50.5-0.40.6-1.0-0.5-0.50.7-0.20.7-0.60.90.7-0.61.01.30.6-0.50.9-0.21.0-1.0-1.1-0.70.3
Locomotion velocity, session 22.52.94.5-1.7-1.91.8-1.71.9-2.1-1.8-1.81.9-1.61.9-1.41.81.8-1.71.92.01.5-1.61.8-1.31.8-1.6-1.8-0.00.1
Locomotion distance, session 20.50.71.7-0.4-0.70.7-0.50.8-1.0-0.7-0.70.9-0.30.9-1.00.71.1-0.41.31.20.3-0.51.2-0.71.3-1.3-1.3-0.80.1
Locomotion velocity, session 30.40.51.61.10.8-0.70.9-0.6-0.00.80.8-0.60.8-0.71.20.2-0.7-0.2-0.20.40.20.7-0.31.3-0.20.4-0.0-0.70.7
Locomotion distance, session 30.10.10.20.40.3-0.30.3-0.30.20.20.2-0.20.3-0.30.5-0.0-0.20.1-0.10.1-0.10.2-0.10.3-0.00.10.1-0.30.2
Stereotopy head waving bouts, day 30.70.82.21.51.2-1.11.2-1.00.31.01.0-0.91.2-1.01.0-0.3-0.80.4-0.30.1-0.31.1-0.51.3-0.30.50.1-1.01.4
Stereotopy head waving duration, day 30.70.81.61.31.2-1.01.2-1.00.61.11.1-1.11.1-1.11.0-0.6-1.00.5-0.7-0.5-0.41.0-0.81.2-0.70.80.6-0.40.7
Locomotion velocity, session 70.60.61.71.10.9-0.90.9-0.70.21.01.0-0.90.8-0.91.3-0.2-1.00.2-0.6-0.2-0.01.0-0.81.3-0.70.80.5-0.20.6
Locomotion distance, session 70.20.31.40.80.5-0.60.5-0.50.20.50.5-0.30.9-0.40.8-0.4-0.30.50.20.2-0.50.60.10.20.2-0.2-0.3-1.20.3
Stereotopy head waving bouts, day 70.30.31.20.10.3-0.10.2-0.1-0.10.40.4-0.4-0.2-0.3-0.20.4-0.4-0.5-0.8-0.20.70.1-0.81.1-0.80.80.81.10.7
Stereotopy head waving duration, day 71.11.42.9-1.4-1.21.3-1.31.4-1.4-1.1-1.11.1-1.61.3-1.31.61.0-1.70.61.11.7-1.40.6-0.20.5-0.5-0.51.20.2
Locomotion velocity, session 81.01.13.2-0.6-1.00.8-0.90.8-0.8-0.9-0.91.1-0.41.0-1.80.71.4-0.31.51.30.1-0.91.4-1.21.4-1.5-1.4-1.0-0.0
Locomotion distance, session 80.20.32.10.80.4-0.60.5-0.50.10.50.5-0.40.5-0.6-0.30.2-0.3-0.1-0.30.30.10.5-0.31.0-0.30.40.1-0.41.4
Degree of sensitization distance0.10.10.40.60.3-0.30.3-0.3-0.30.40.4-0.20.4-0.20.60.0-0.2-0.00.20.30.00.40.00.40.10.0-0.3-0.60.5
Degree of sensitization stereotypy0.70.82.3-1.0-0.81.0-0.91.1-1.0-0.6-0.60.6-1.30.8-1.11.30.6-1.40.10.61.5-0.90.10.3-0.0-0.00.01.50.3
Conditioned locomotion1.31.62.5-1.2-1.31.3-1.31.3-1.4-1.3-1.31.4-1.11.3-1.61.21.5-1.01.51.40.9-1.21.4-1.11.4-1.3-1.3-0.1-0.6
Cocaine response after cond. corrected1.51.73.31.81.4-1.61.4-1.61.41.51.5-1.31.8-1.61.7-1.4-1.21.5-0.7-0.8-1.51.2-0.70.8-0.60.60.5-1.50.1
Cocaine response after cond. not corrected1.01.22.31.51.1-1.41.1-1.41.11.11.1-1.01.5-1.41.5-1.0-0.91.2-0.6-0.6-1.20.9-0.60.7-0.50.50.3-1.30.6
Cocaine response before conditioning0.81.01.9-1.3-1.11.1-1.11.2-1.0-1.2-1.21.0-1.41.0-1.11.11.0-1.10.50.71.1-1.20.5-0.60.4-0.5-0.51.00.6
Saline control response3.74.86.6-2.3-2.52.3-2.52.2-2.3-2.5-2.52.6-2.02.4-2.11.92.5-1.72.52.31.4-2.32.5-2.32.4-2.2-2.4-0.4-0.2
Bone: connectivity density2.33.66.5-1.9-2.02.0-2.02.0-2.5-2.0-2.02.0-2.12.0-1.62.51.9-2.51.62.42.4-2.11.5-0.71.4-1.4-1.80.70.3
Bone: cortical apparent density0.20.31.2-0.6-0.60.5-0.60.5-0.0-0.6-0.60.5-0.30.4-0.4-0.20.50.20.6-0.0-0.3-0.50.6-1.10.6-0.6-0.3-0.2-0.5
Bone: cortical area0.71.12.5-1.2-1.01.2-1.01.2-1.3-1.0-1.01.0-1.41.0-1.01.40.8-1.60.61.01.6-1.10.5-0.20.4-0.3-0.51.10.3
Bone: cortical porosity0.10.10.4-0.2-0.20.3-0.20.3-0.5-0.1-0.10.2-0.20.3-0.60.10.3-0.10.30.10.1-0.20.2-0.10.2-0.1-0.10.1-0.0
Bone: cortical porosity0.50.61.6-0.7-0.70.8-0.70.9-1.0-0.7-0.70.8-0.60.8-1.20.60.9-0.40.90.60.4-0.80.8-0.70.8-0.7-0.70.0-0.3
Bone: cortical thickness2.33.86.9-2.2-2.32.1-2.32.0-1.6-2.3-2.32.2-1.72.1-1.81.12.2-1.02.31.60.7-2.22.2-2.62.2-2.1-1.9-0.3-1.4
Bone: cortical thickness0.70.82.2-0.4-0.80.5-0.80.5-0.2-0.8-0.80.9-0.00.7-0.3-0.00.90.31.20.7-0.5-0.81.3-1.51.3-1.4-1.3-1.3-0.8
Bone: cortical tissue density0.30.41.5-0.7-0.70.6-0.70.6-0.1-0.6-0.60.6-0.40.5-0.5-0.20.60.20.80.1-0.3-0.50.7-1.20.7-0.7-0.4-0.3-0.7
Condit. Reinf. active minus inactive responses0.10.10.5-0.3-0.40.3-0.40.3-0.3-0.4-0.40.4-0.20.2-0.70.20.3-0.20.50.30.1-0.30.4-0.50.4-0.1-0.3-0.20.3
Condit. Reinf. active-inactive response ratio0.00.10.4-0.3-0.10.2-0.20.10.1-0.2-0.20.1-0.10.0-0.7-0.20.20.20.2-0.2-0.3-0.10.2-0.50.10.00.1-0.10.1
Condit. Reinf. active responses0.00.00.3-0.1-0.10.1-0.00.2-0.3-0.1-0.10.0-0.2-0.1-0.10.2-0.2-0.30.00.10.40.1-0.00.2-0.10.40.10.10.6
Condit. Reinf. inactive responses0.20.21.10.40.3-0.30.4-0.1-0.20.40.4-0.40.0-0.40.50.4-0.6-0.5-0.50.10.60.4-0.51.0-0.60.70.30.40.8
Incentive salience index mean0.20.30.6-0.5-0.60.5-0.50.5-0.7-0.6-0.60.6-0.40.4-0.80.60.4-0.60.60.70.5-0.40.6-0.40.5-0.2-0.5-0.20.6
Condit. Reinf. lever presses0.30.41.2-0.6-0.60.6-0.50.7-1.0-0.7-0.70.6-0.80.5-0.61.00.5-1.10.40.91.1-0.50.40.00.4-0.1-0.50.40.6
Condit. Reinf. active minus inactive responses0.30.41.90.20.5-0.20.5-0.2-0.00.40.4-0.5-0.1-0.5-0.20.2-0.6-0.3-0.9-0.50.50.2-1.01.1-1.01.10.91.11.4
Condit. Reinf. active-inactive response ratio1.31.44.80.61.0-0.61.0-0.50.10.90.9-1.1-0.0-0.90.10.3-1.2-0.5-1.5-0.70.80.7-1.72.1-1.71.91.51.62.2
Condit. Reinf. active responses0.10.10.8-0.3-0.10.3-0.10.3-0.4-0.2-0.20.1-0.40.1-0.50.40.1-0.4-0.20.00.5-0.3-0.20.2-0.20.40.30.70.9
Condit. Reinf. inactive responses0.40.51.7-0.6-0.80.5-0.80.5-0.3-0.8-0.80.8-0.20.6-0.50.00.90.10.90.6-0.3-0.71.1-1.31.1-0.9-0.9-0.7-0.4
Condit. Reinf. lever presses2.12.95.6-2.0-1.82.0-1.82.0-2.1-1.7-1.71.6-2.31.7-1.92.21.6-2.30.91.62.4-1.80.9-0.40.8-0.8-0.91.80.5
Condit. Reinf. lever reinforcers received0.20.31.0-0.8-0.50.7-0.50.7-0.7-0.6-0.60.5-0.90.5-0.80.70.4-0.80.10.30.9-0.70.0-0.0-0.00.1-0.01.00.6
Conditioned reinforcement - actives0.50.53.00.10.6-0.10.6-0.00.10.70.7-0.6-0.3-0.4-0.30.1-0.6-0.2-0.8-0.70.50.7-1.11.1-1.20.91.11.7-0.1
Conditioned reinforcement - inactives5.66.410.32.02.7-2.42.7-2.32.62.72.7-2.81.5-2.83.0-1.8-2.91.2-3.2-2.8-0.92.4-3.12.7-3.23.13.21.6-0.1
Conditioned locomotion8.310.018.43.13.6-3.13.6-3.03.33.63.6-3.62.7-3.34.3-2.9-3.62.4-3.5-3.6-2.12.9-3.53.0-3.43.23.40.7-0.0
Patch foraging indifference point 0 sec0.10.10.80.10.2-0.10.2-0.10.10.30.3-0.30.1-0.10.9-0.3-0.40.0-0.1-0.4-0.0-0.7-0.20.2-0.20.30.30.1-0.1
Patch foraging indifference point AUC3.64.27.2-2.6-2.62.3-2.72.3-2.1-2.2-2.22.3-2.62.2-2.12.31.9-2.41.61.92.2-2.01.5-1.41.3-1.2-1.31.4-0.6
Delay disc. indifference point, 0s delay0.20.21.30.90.3-0.70.3-0.70.50.20.2-0.20.8-0.4-0.4-0.0-0.10.40.10.5-0.40.10.20.40.2-0.1-0.5-1.10.2
Delay disc. indifference point, 16s delay0.90.92.80.80.8-1.00.9-0.90.90.90.9-0.90.6-1.11.7-0.5-1.10.3-1.2-0.8-0.21.0-1.11.0-1.11.01.00.2-1.0
Delay disc. indifference point, 2s delay0.10.11.00.30.1-0.20.1-0.20.1-0.1-0.1-0.10.1-0.1-0.30.4-0.0-0.2-0.20.30.30.4-0.20.5-0.20.1-0.1-0.01.0
Delay disc. indifference point, 24s delay0.30.21.40.20.1-0.40.0-0.50.4-0.0-0.00.00.5-0.20.7-0.6-0.00.60.2-0.1-0.80.40.4-0.70.4-0.2-0.3-1.2-1.1
Delay disc. indifference point, 4s delay0.20.22.00.50.1-0.50.1-0.60.4-0.2-0.20.10.7-0.10.1-0.20.10.50.30.4-0.6-0.10.5-0.30.5-0.3-0.5-1.4-0.2
Delay disc. indifference point, 8s delay0.20.21.30.40.0-0.30.0-0.30.20.10.10.10.50.0-0.7-0.10.50.50.40.5-0.50.00.5-0.30.6-0.8-0.8-1.2-0.7
Indifference point function ln k7.810.918.44.23.8-4.03.9-4.03.73.73.7-3.54.3-3.73.2-3.7-3.13.8-2.6-2.9-3.73.3-2.42.2-2.12.12.1-2.51.0
Indifference point function log k7.810.918.44.23.8-4.03.9-4.03.73.73.7-3.54.3-3.73.2-3.7-3.13.8-2.6-2.9-3.73.3-2.42.2-2.12.12.1-2.51.0
Patch foraging total patch changes 0 sec0.10.10.80.20.2-0.10.2-0.20.20.20.2-0.20.3-0.00.9-0.5-0.30.30.1-0.4-0.4-0.80.0-0.20.10.10.1-0.4-0.4
Patch foraging total patch changes 12 sec4.55.810.8-2.8-2.92.7-3.02.7-2.5-2.6-2.62.7-2.72.7-1.32.52.4-2.62.22.42.3-3.32.2-2.02.0-1.9-2.10.8-1.1
Patch foraging total patch changes 18 sec0.81.02.3-1.3-1.31.0-1.31.0-1.1-1.2-1.21.0-1.31.0-1.01.10.8-1.20.50.81.1-1.50.6-0.60.4-0.1-0.40.90.8
Patch foraging total patch changes 24 sec2.43.04.8-2.2-2.11.9-2.11.9-1.7-1.9-1.92.0-2.01.9-0.41.61.6-1.91.71.61.7-2.21.7-1.71.5-1.1-1.40.5-0.9
Patch foraging total patch changes 6 sec0.71.12.0-1.0-1.21.0-1.21.0-1.2-1.0-1.01.2-0.91.1-0.61.01.1-1.01.31.30.8-1.41.2-0.91.2-0.9-1.1-0.30.5
Patch foraging time to switch 0 sec1.62.55.7-1.6-1.51.7-1.61.8-2.3-1.6-1.61.6-1.91.7-1.12.41.4-2.41.12.02.4-1.21.0-0.10.9-0.8-1.21.20.9
Patch foraging water rate 0 sec3.76.010.12.42.6-2.72.6-2.83.22.52.5-2.62.6-2.72.7-3.1-2.52.8-2.4-3.0-2.72.0-2.21.2-2.22.12.3-0.80.3
Patch foraging water rate 12 sec7.711.819.63.93.9-3.93.9-4.04.43.63.6-3.64.2-3.73.5-4.4-3.34.3-2.7-3.7-4.33.2-2.51.4-2.22.12.5-2.40.1
Patch foraging water rate 18 sec3.24.37.62.52.4-2.52.5-2.52.42.22.2-2.12.8-2.22.2-2.6-1.92.6-1.3-1.9-2.62.0-1.30.9-1.11.21.1-1.90.9
Patch foraging water rate 24 sec3.65.08.12.52.5-2.72.6-2.72.82.22.2-2.32.7-2.52.0-2.7-1.92.7-2.1-2.3-2.61.8-1.71.1-1.61.51.5-1.42.2
Patch foraging water rate 6 sec4.26.210.82.92.6-2.92.6-3.03.12.42.4-2.53.2-2.73.0-3.3-2.43.2-1.8-2.5-3.32.4-1.50.7-1.31.41.6-2.30.5
Seeking ratio, delayed vs. immediate footshock0.20.20.90.50.5-0.40.5-0.40.50.10.1-0.40.5-0.40.9-0.6-0.50.5-0.2-0.5-0.50.3-0.20.0-0.20.20.3-0.4-0.4
Distance traveled before self-admin0.70.82.1-1.1-0.81.1-0.91.1-1.2-0.7-0.70.8-1.30.8-0.21.20.5-1.40.50.71.5-1.10.2-0.00.2-0.3-0.21.3-0.6
Distance traveled after self-admin0.20.20.8-0.7-0.30.6-0.30.6-0.3-0.2-0.20.3-0.70.4-0.00.40.2-0.60.20.10.6-0.70.0-0.10.0-0.10.10.9-0.5
Extensor digitorum longus weight6.927.237.3-5.4-5.65.7-5.75.7-6.1-5.7-5.75.8-5.35.8-4.95.55.6-5.25.45.84.7-5.65.2-4.05.1-4.6-5.10.6-0.5
Bone: elastic displacement1.61.85.21.51.2-1.41.2-1.51.71.11.1-1.11.9-1.21.4-2.1-1.12.2-0.5-1.4-2.31.3-0.4-0.3-0.30.40.7-1.7-0.7
Bone: elastic work0.81.02.9-0.5-0.80.6-0.80.5-0.4-0.9-0.91.0-0.00.8-0.3-0.01.10.31.40.8-0.5-0.81.5-1.71.6-1.4-1.3-1.6-0.9
Bone: endosteal estimation0.91.97.11.41.4-1.21.4-1.10.21.41.4-1.30.6-1.21.10.4-1.3-0.5-1.5-0.10.81.5-1.62.7-1.51.81.00.62.7
Bone: endosteal perimeter1.32.711.01.31.6-1.21.6-1.00.11.61.6-1.50.3-1.40.60.7-1.5-0.9-2.0-0.41.31.5-2.23.3-2.22.31.61.73.1
Epididymis fat weight2.25.110.52.42.6-2.52.5-2.42.02.42.4-2.51.9-2.73.2-1.3-2.61.0-2.7-1.8-0.81.1-2.62.8-2.52.82.30.41.7
Delta time in closed arm before/after self-admin1.01.05.50.70.1-0.4-0.0-0.40.20.10.10.11.10.11.8-0.8-0.00.90.90.3-1.2-0.00.9-0.91.1-1.1-1.2-2.3-2.2
Delta time in open arm before/after self-admin0.60.63.5-1.1-0.60.7-0.40.7-0.3-0.6-0.60.4-1.30.2-0.40.80.1-1.1-0.4-0.01.2-0.5-0.30.1-0.50.70.81.90.9
Diff in mean of infusions in LGA sessions0.40.41.7-0.9-0.80.7-0.80.7-0.4-0.7-0.70.7-0.80.60.40.30.4-0.40.50.30.4-1.30.5-0.90.4-0.2-0.10.4-0.9
Delay discount exponential model param0.10.10.5-0.20.10.20.10.2-0.00.20.2-0.2-0.2-0.10.1-0.2-0.30.0-0.2-0.50.0-0.0-0.30.1-0.30.40.60.70.7
Extinction: sum of active levers before priming4.44.46.1-2.4-2.42.4-2.32.4-2.5-2.4-2.42.3-2.42.3-2.12.32.2-2.32.12.22.1-2.11.9-1.51.8-1.5-1.60.9-0.2
Active lever presses in extinction session 62.72.65.0-2.2-1.92.0-1.92.0-1.8-1.6-1.61.7-2.21.7-1.11.81.4-1.91.21.21.9-2.11.0-1.00.8-0.8-0.71.6-0.9
Bone: final force2.84.67.6-2.3-2.22.4-2.22.5-2.8-2.2-2.22.3-2.42.2-2.02.72.2-2.72.02.52.6-2.21.8-1.01.7-1.6-1.90.90.2
Bone: final moment2.54.16.7-2.1-2.12.3-2.12.3-2.6-2.1-2.12.2-2.32.1-1.82.62.0-2.51.92.32.4-2.11.7-1.01.6-1.5-1.80.90.2
Food consumed during 24 hour testing period0.10.10.9-0.6-0.30.4-0.30.40.0-0.3-0.30.1-0.60.3-0.00.20.0-0.4-0.2-0.30.4-0.2-0.2-0.1-0.30.20.31.0-0.4
Glucose1.82.75.32.01.8-1.91.8-1.81.21.91.9-1.91.5-2.01.6-0.8-1.80.8-1.8-1.1-0.61.9-1.82.3-1.71.71.40.01.6
Heart weight3.34.68.72.72.5-2.62.4-2.62.42.42.4-2.42.6-2.52.9-2.1-2.22.1-1.9-1.8-2.01.7-1.81.7-1.61.71.5-1.20.7
Delay discount hyperbolic model param0.10.10.4-0.10.10.10.10.10.00.20.2-0.2-0.1-0.10.3-0.3-0.40.1-0.2-0.6-0.00.0-0.40.1-0.40.40.60.70.4
Intermittent access intake day 1-15 change0.70.72.10.20.7-0.60.7-0.60.80.70.7-0.8-0.0-0.9-0.2-0.4-0.80.2-1.2-1.1-0.00.3-1.20.8-1.41.21.41.3-0.2
Intermittent access intake escalation0.60.61.70.20.6-0.60.6-0.50.70.70.7-0.80.0-0.80.0-0.4-0.80.2-1.1-1.0-0.00.1-1.20.8-1.31.21.31.2-0.2
Intermittent access intake escalation 20.30.31.9-0.30.3-0.10.3-0.10.40.30.3-0.4-0.4-0.40.3-0.1-0.5-0.2-0.8-0.80.3-0.2-0.80.5-1.00.91.11.4-0.6
Intermitt. access day 1 inactive lever presses2.32.43.31.51.7-1.61.7-1.51.51.81.8-1.81.3-1.71.4-1.2-1.71.1-1.8-1.6-0.91.8-1.81.7-1.81.71.70.40.5
Intermitt. access day 15 inactive lever presses3.23.58.71.41.9-1.61.9-1.41.52.02.0-2.00.9-1.93.0-1.0-2.30.5-2.2-1.9-0.21.7-2.42.3-2.42.52.31.5-0.3
Intermitt. access escalation Index2.92.65.72.01.7-2.01.7-2.01.91.51.5-1.62.0-1.82.4-1.7-1.71.7-1.3-1.3-1.71.5-1.00.9-0.91.00.8-1.51.4
Intermittent access day 1 total infusions4.95.611.82.82.8-2.62.8-2.41.82.92.9-2.72.1-2.62.8-1.2-2.51.0-2.7-1.7-0.62.1-2.73.4-2.62.72.10.41.6
Intermittent access day 15 total infusions7.48.314.42.83.3-3.03.3-2.82.63.43.4-3.32.1-3.32.7-1.7-3.11.4-3.6-2.7-0.92.2-3.63.8-3.63.53.21.41.1
Intermittent access terminal intake (last 3 days)5.15.613.12.12.7-2.32.7-2.21.82.62.6-2.61.3-2.72.4-0.8-2.50.4-3.1-1.90.11.3-3.13.6-3.23.22.71.81.2
Intermittent access total infusions4.55.011.42.22.6-2.22.6-2.11.62.72.7-2.61.5-2.52.4-0.9-2.50.6-2.8-1.8-0.21.7-2.93.4-2.82.92.41.31.2
Intermittent access day 1 locomotion3.33.56.42.42.2-2.32.2-2.21.52.22.2-2.12.0-2.12.5-1.0-2.01.0-1.9-1.0-0.81.3-1.82.5-1.61.81.2-0.71.7
Intermittent access day 15 total locomotion4.54.88.22.02.4-2.22.4-2.12.02.52.5-2.41.4-2.52.9-1.2-2.40.8-2.8-2.0-0.51.4-2.82.9-2.82.82.51.30.8
Intermittent access total locomotion5.76.514.72.52.8-2.62.8-2.41.92.92.9-2.81.6-2.93.3-0.9-2.90.5-3.2-1.8-0.11.7-3.23.8-3.23.42.71.41.8
Intermittent access standard deviation1.21.22.50.81.3-1.01.3-1.01.11.21.2-1.30.6-1.20.5-0.8-1.20.6-1.4-1.4-0.40.4-1.51.3-1.51.41.61.00.4
Left kidney weight0.51.44.61.01.3-1.11.4-1.11.11.21.2-1.30.7-1.32.2-0.7-1.30.4-1.6-1.1-0.20.8-1.51.5-1.51.41.30.90.3
Right kidney weight0.30.73.30.10.6-0.20.6-0.10.20.50.5-0.7-0.3-0.41.20.3-0.8-0.6-1.2-0.60.8-0.0-1.21.4-1.31.31.11.80.3
Cocaine induced anxiety0.10.21.0-0.4-0.20.3-0.20.3-0.4-0.1-0.10.1-0.60.1-0.30.60.2-0.7-0.10.20.80.2-0.20.4-0.30.30.21.0-0.0
Post-drug Anxiety1.31.42.9-1.5-1.11.4-1.11.5-1.5-1.0-1.01.1-1.71.2-1.61.61.2-1.60.91.01.7-0.90.6-0.30.4-0.5-0.41.5-0.7
Baseline Anxiety1.92.14.0-1.4-1.51.5-1.51.5-1.4-1.5-1.51.6-1.21.6-1.21.11.5-1.01.71.40.8-2.01.6-1.61.6-1.6-1.5-0.3-1.3
Tail length0.82.56.1-1.6-2.01.5-2.01.4-0.9-1.8-1.81.8-1.11.8-1.60.61.8-0.41.81.20.1-1.71.9-2.51.9-1.9-1.5-0.7-1.1
Length with tail1.96.89.7-2.8-2.92.9-2.82.9-2.6-2.8-2.83.0-2.52.9-1.72.22.9-2.12.92.61.8-3.12.9-2.72.9-2.8-2.70.2-2.1
Length without tail1.63.45.4-1.9-1.72.1-1.72.2-2.3-1.7-1.71.9-1.92.0-0.31.91.9-2.02.01.91.8-2.31.8-1.31.9-1.8-1.90.4-1.7
Times rat made contact with spout0.50.61.6-0.7-0.80.6-0.80.5-0.4-0.7-0.70.8-0.30.7-1.20.11.00.11.00.5-0.2-0.61.0-1.31.0-1.0-0.8-0.6-0.4
Lifetime Intake3.84.39.32.32.5-2.22.5-2.11.62.52.5-2.41.7-2.32.3-1.0-2.20.8-2.5-1.6-0.51.5-2.53.0-2.42.42.00.71.1
Liver weight, left0.10.12.10.50.2-0.30.2-0.2-0.00.20.2-0.20.3-0.2-0.60.2-0.10.1-0.20.20.10.1-0.20.6-0.20.20.10.01.5
Liver weight, right0.10.21.10.60.2-0.50.2-0.40.10.20.2-0.00.6-0.20.10.20.00.10.20.7-0.10.00.20.30.3-0.0-0.4-1.00.9
Locomotor activity2.03.26.42.12.0-2.21.9-2.32.41.81.8-1.72.4-1.81.8-2.4-1.52.5-1.2-1.7-2.51.2-1.00.4-0.90.90.9-1.90.9
Locomotor testing distance2.84.710.02.62.3-2.72.2-2.82.92.12.1-2.03.1-2.22.3-2.9-1.93.1-1.2-1.9-3.21.5-1.00.3-0.80.90.9-2.70.5
Locomotor testing rearing2.13.36.32.22.0-2.32.0-2.32.41.91.9-1.82.5-1.91.7-2.3-1.72.4-1.1-1.6-2.41.2-1.00.6-0.90.80.9-2.00.3
Locomotion in novel chamber4.35.39.02.02.6-2.22.6-2.11.92.52.5-2.61.5-2.72.2-1.4-2.71.0-2.9-2.3-0.62.2-2.92.9-2.93.02.91.41.2
Locomotion in novel chamber post-restriction2.73.34.61.92.0-2.02.0-1.91.92.02.0-2.11.7-2.01.3-1.6-1.91.5-2.2-1.9-1.22.0-2.11.9-2.11.81.80.30.9
Fecal boli incidents, locomotor time 10.70.74.9-0.8-0.60.7-0.40.7-0.6-0.4-0.40.3-1.20.3-0.81.10.1-1.3-0.50.31.4-0.5-0.50.7-0.60.70.42.21.2
Change in fecal boli incidents, locomotor task0.60.54.00.90.4-0.50.3-0.60.10.20.2-0.11.1-0.2-0.5-0.60.31.00.70.3-1.10.70.7-0.40.9-0.7-0.8-2.0-0.1
Time >=10cm from walls, locomotor time 11.11.14.90.60.8-0.50.6-0.4-0.20.60.6-0.8-0.1-0.8-0.70.7-0.8-0.7-1.3-0.21.10.6-1.42.2-1.41.81.11.42.2
Bouts of movement, locomotor time 11.21.35.9-1.7-1.21.4-1.31.4-0.5-1.1-1.11.1-1.31.3-1.00.21.0-0.40.9-0.00.3-1.30.8-1.70.7-0.9-0.30.9-2.4
Total resting periods, locomotor time 10.91.05.2-1.5-1.01.3-1.01.2-0.4-0.9-0.90.9-1.31.1-0.70.30.8-0.50.6-0.10.4-1.20.5-1.30.4-0.6-0.11.2-2.3
Rest time, locomotor task time 11.31.52.61.11.4-1.21.1-1.21.31.21.2-1.41.2-1.20.7-1.5-1.31.4-1.3-1.6-1.21.4-1.30.7-1.21.31.50.10.3
Distance moved, locomotor task time 10.20.30.9-0.2-0.30.3-0.10.3-0.6-0.5-0.50.5-0.40.2-0.80.80.5-0.70.30.90.7-1.00.40.10.4-0.3-0.6-0.20.3
Vertical activity count, locomotor time 11.21.22.01.41.4-1.31.4-1.31.21.31.3-1.21.2-1.30.6-0.8-1.10.8-1.2-0.8-0.70.8-1.11.2-1.01.00.9-0.40.8
Time >=10cm from walls, locomotor time 20.30.31.8-0.6-0.20.5-0.30.6-0.4-0.3-0.30.1-0.80.1-1.20.50.1-0.6-0.2-0.20.8-0.3-0.30.4-0.40.50.61.3-0.1
Bouts of movement, locomotor time 20.50.54.1-0.8-0.70.8-0.70.7-0.4-0.7-0.70.7-0.70.70.30.30.5-0.40.60.30.3-0.70.6-0.90.5-0.6-0.40.3-2.0
Total resting periods, locomotor time 20.20.21.8-0.6-0.40.5-0.50.4-0.2-0.4-0.40.4-0.50.40.30.20.2-0.30.30.20.3-0.50.3-0.50.3-0.2-0.10.3-1.3
Rest time, locomotor task time 22.32.73.92.02.0-1.81.8-1.81.51.81.8-1.91.7-1.81.0-1.4-1.71.5-1.6-1.5-1.21.8-1.71.7-1.51.71.5-0.11.5
Distance moved, locomotor task time 21.11.32.5-1.4-1.21.3-1.11.2-1.1-1.2-1.21.2-1.21.2-1.60.91.3-0.81.10.90.7-1.61.1-1.21.0-1.1-0.90.2-0.9
Vertical activity count, locomotor time 20.30.31.40.20.1-0.30.3-0.40.60.00.0-0.00.6-0.20.1-0.90.11.00.2-0.4-1.1-0.00.4-0.90.3-0.4-0.2-1.2-0.6
Light reinforcement 10.10.20.50.30.4-0.40.3-0.40.60.40.4-0.40.4-0.3-0.1-0.7-0.40.6-0.3-0.7-0.6-0.0-0.3-0.0-0.30.30.5-0.30.5
Light reinforcement 21.31.74.20.71.3-0.71.3-0.50.51.51.5-1.40.2-0.91.8-0.3-1.8-0.2-1.6-1.40.51.1-1.92.0-1.91.71.81.8-0.3
Bone: marrow area0.91.97.21.51.5-1.31.5-1.10.21.51.5-1.30.8-1.31.10.3-1.3-0.4-1.5-0.10.71.5-1.62.7-1.51.71.00.52.7
Bone: maximum diameter0.61.04.1-0.9-0.50.9-0.51.0-1.2-0.5-0.50.5-1.50.6-0.91.60.4-1.9-0.20.72.0-0.6-0.30.9-0.40.50.11.91.2
Bone: maximum force3.35.712.5-2.4-2.32.6-2.32.8-3.3-2.3-2.32.4-2.92.3-1.93.52.1-3.51.82.93.5-2.31.6-0.31.5-1.2-1.81.60.9
Bone: maximum moment2.84.910.8-2.2-2.22.4-2.22.5-3.1-2.2-2.22.2-2.72.1-1.63.22.0-3.31.72.73.3-2.11.5-0.31.4-1.1-1.71.40.8
Mean time between licks in bursts0.71.03.5-0.3-0.80.4-0.80.2-0.2-0.6-0.60.90.20.5-0.3-0.21.00.51.50.8-0.8-0.61.6-1.71.7-1.4-1.3-1.9-0.9
Mean num. licks in bursts0.20.30.90.50.4-0.50.4-0.60.60.40.4-0.30.7-0.50.1-0.8-0.30.9-0.0-0.5-1.00.5-0.0-0.30.00.00.2-0.80.1
Cd content in liver1.11.22.70.60.9-0.80.9-0.81.10.90.9-1.10.3-1.0-0.0-0.4-1.00.2-1.6-1.10.01.1-1.51.3-1.71.71.51.21.4
Co content in liver1.82.17.31.41.2-1.51.2-1.62.21.21.2-1.22.0-1.20.6-2.4-1.02.6-0.6-1.7-2.71.3-0.4-0.6-0.30.30.7-1.7-0.9
Cu content in liver0.20.30.6-0.7-0.80.6-0.70.7-0.4-0.7-0.70.5-0.60.6-0.70.30.4-0.40.60.30.3-0.40.5-0.60.4-0.4-0.30.2-0.4
Fe content in liver0.30.41.1-0.6-0.60.5-0.60.5-0.7-0.6-0.60.5-0.80.5-0.91.00.3-1.00.10.61.1-0.30.10.2-0.10.1-0.10.40.9
K content in liver1.61.63.5-1.0-1.41.2-1.41.2-1.7-1.3-1.31.4-1.11.2-1.21.71.2-1.51.31.91.4-1.11.2-0.51.2-0.8-1.30.00.7
Mg content in liver0.10.10.50.0-0.20.1-0.20.2-0.7-0.1-0.10.2-0.20.10.10.7-0.1-0.70.30.70.7-0.00.10.40.20.2-0.2-0.10.6
Mn content in liver2.32.64.8-2.0-1.72.0-1.72.0-2.1-1.7-1.71.6-2.21.7-1.72.01.2-2.11.21.42.1-1.80.9-0.70.8-0.6-0.71.5-0.5
Na content in liver1.11.12.0-1.2-1.11.3-1.11.4-1.4-1.1-1.11.1-1.31.2-1.01.30.9-1.31.01.01.3-0.90.8-0.50.8-0.7-0.80.9-0.4
Rb content in liver1.51.83.01.71.4-1.61.5-1.61.31.61.6-1.51.6-1.61.3-1.1-1.51.2-1.2-1.0-1.01.5-1.31.4-1.21.31.2-0.60.9
Se content in liver0.50.73.7-0.7-0.10.4-0.10.4-0.6-0.2-0.2-0.1-1.10.00.40.9-0.4-1.3-0.8-0.21.50.0-0.91.0-1.11.00.91.90.4
Sr content in liver3.22.94.8-2.2-2.02.1-2.02.0-1.5-1.9-1.91.9-2.02.0-1.01.41.6-1.61.61.31.4-2.01.5-1.71.4-1.5-1.30.9-2.0
Zn content in liver1.11.22.0-1.3-1.31.2-1.31.3-1.1-1.3-1.31.2-1.31.30.01.20.8-1.41.01.01.3-1.40.9-0.80.8-0.7-0.80.3-0.7
Bone: minimum diameter0.81.45.21.21.3-1.11.3-0.90.21.21.2-1.10.5-1.11.10.3-1.3-0.5-1.3-0.20.71.2-1.42.3-1.41.61.00.62.1
Time in familiar zone, hab. session 10.30.21.30.50.4-0.60.3-0.50.30.60.6-0.40.4-0.41.1-0.3-0.40.2-0.5-0.3-0.20.5-0.40.5-0.40.70.3-0.10.8
Time in novel zone, hab. session 10.30.31.20.70.5-0.60.6-0.60.80.40.4-0.40.9-0.4-0.3-0.7-0.30.90.1-0.3-1.00.40.1-0.10.1-0.3-0.0-1.1-0.5
Total zone transitions, hab. session 10.50.83.3-0.8-0.91.0-0.81.1-1.0-0.8-0.80.8-0.81.0-1.80.90.9-0.80.90.80.8-0.70.8-0.50.8-0.7-0.60.20.2
Total locomotion distance, hab. session 10.30.41.60.90.8-0.60.9-0.50.20.70.7-0.70.6-0.6-0.1-0.1-0.60.1-0.5-0.2-0.00.8-0.71.1-0.60.80.6-0.01.3
Locomotion velocity, hab. session 10.10.10.40.30.3-0.10.4-0.0-0.20.20.2-0.20.2-0.2-0.50.1-0.2-0.1-0.10.10.20.3-0.20.5-0.10.30.20.10.7
Time in familiar zone, hab. session 20.40.42.60.3-0.0-0.4-0.1-0.50.50.10.10.20.70.00.2-0.70.41.00.50.1-1.2-0.10.7-1.00.7-0.6-0.7-1.6-0.3
Time in novel zone, hab. session 20.20.20.8-0.3-0.20.4-0.10.5-0.4-0.2-0.20.1-0.60.1-0.10.6-0.1-0.8-0.00.20.9-0.1-0.20.5-0.20.20.20.80.1
Total zone transitions, hab. session 21.11.52.9-0.9-1.11.2-0.91.4-1.7-1.1-1.11.3-0.91.2-1.41.41.4-1.31.41.71.2-1.11.3-0.51.4-1.2-1.5-0.20.3
Total locomotion distance, hab. session 20.10.11.40.50.3-0.20.4-0.1-0.40.10.1-0.10.4-0.2-0.20.30.1-0.10.20.60.10.40.20.50.30.0-0.3-0.61.2
Locomotion velocity, hab. session 20.20.22.10.60.5-0.40.7-0.2-0.30.30.3-0.30.4-0.4-0.00.2-0.2-0.2-0.10.30.20.6-0.20.9-0.10.4-0.0-0.21.5
Novel to familiar place preference ratio1.71.74.5-1.7-1.31.5-1.51.6-1.5-1.3-1.31.1-2.01.1-0.61.80.9-2.10.31.02.1-1.40.3-0.00.2-0.3-0.52.0-0.3
Novelty place preference0.91.03.0-1.3-0.91.1-1.11.1-1.0-0.9-0.90.7-1.60.7-0.31.40.5-1.60.00.61.7-1.00.00.2-0.1-0.1-0.21.7-0.3
Time in novel zone, NPP test0.70.72.4-1.1-0.80.9-1.01.0-0.9-0.8-0.80.7-1.40.6-0.11.30.4-1.50.00.61.5-1.00.10.1-0.1-0.1-0.21.4-0.3
Total zone transitions, NPP test2.13.15.4-1.7-1.81.9-1.62.0-2.1-1.8-1.81.8-1.71.9-2.32.02.0-1.81.82.01.7-1.81.7-1.01.6-1.6-1.70.30.3
Total locomotion distance, NPP test0.10.10.30.30.10.10.20.2-0.5-0.0-0.00.10.10.1-0.40.40.3-0.20.40.60.30.00.30.30.4-0.2-0.4-0.40.5
Locomotion velocity, NPP test0.10.10.30.10.00.20.10.3-0.5-0.1-0.10.1-0.00.2-0.60.40.3-0.20.40.50.30.10.20.20.3-0.3-0.3-0.10.4
Intraocular pressure1.11.54.30.31.1-0.71.1-0.81.20.70.7-1.20.1-1.21.3-0.9-1.30.5-1.8-1.8-0.30.7-1.80.9-1.91.92.11.8-0.0
Delta distance traveled before/after self-admin0.20.20.80.40.4-0.40.4-0.50.70.30.3-0.20.6-0.2-0.2-0.6-0.00.8-0.0-0.2-0.90.00.1-0.30.2-0.2-0.1-0.90.5
Delta ambulatory time before/after self-admin0.20.31.40.50.3-0.40.3-0.40.60.20.2-0.10.7-0.1-0.6-0.60.10.90.2-0.1-0.90.20.4-0.40.4-0.4-0.3-1.20.7
Parametrial fat weight1.73.29.22.01.8-2.11.7-2.01.42.02.0-1.91.5-2.21.4-0.6-1.70.6-2.3-0.9-0.41.4-2.02.6-1.92.21.60.43.0
Pavlov. Cond. lever latency0.30.41.00.70.7-0.60.7-0.70.90.80.8-0.70.8-0.60.1-0.9-0.51.0-0.5-0.8-0.90.4-0.50.2-0.50.20.6-0.3-0.3
Pavlov. Cond. magazine entry latency0.30.41.4-0.7-0.60.6-0.60.7-0.8-0.7-0.70.6-0.90.6-0.21.00.3-1.20.20.81.2-0.60.30.10.20.1-0.30.60.1
Pavlov. Cond. change in total contacts0.30.32.1-0.6-0.20.5-0.20.6-0.5-0.3-0.30.1-0.90.20.10.8-0.1-1.1-0.40.11.2-0.0-0.40.6-0.50.40.31.50.2
Pavlov. Cond. index score0.20.30.7-0.8-0.60.6-0.60.6-0.6-0.7-0.70.5-0.80.5-0.30.70.3-0.80.20.40.8-0.50.2-0.20.1-0.0-0.10.7-0.1
Pavlov. Cond. latency score0.10.20.4-0.5-0.50.4-0.50.4-0.5-0.5-0.50.4-0.60.3-0.20.50.2-0.70.20.40.6-0.30.2-0.10.20.0-0.20.40.2
Pavlov. Cond. lever contacts0.00.10.1-0.1-0.30.1-0.30.1-0.3-0.3-0.30.3-0.20.1-0.00.30.2-0.30.20.40.3-0.00.2-0.10.2-0.1-0.3-0.10.3
Pavlov. Cond. magazine entry number0.40.51.51.10.8-0.90.7-0.90.60.80.8-0.61.1-0.70.5-0.8-0.41.0-0.1-0.3-1.00.8-0.10.3-0.00.0-0.0-1.20.6
Pavlov. Cond. intertrial magazine entries0.70.82.10.50.8-0.70.7-0.71.10.90.9-1.00.5-0.91.2-1.0-1.10.8-1.2-1.4-0.70.8-1.10.5-1.20.91.20.5-0.5
Pavlov. Cond. lever-magazine prob. diff.0.50.61.1-1.0-0.80.9-0.80.9-0.9-0.9-0.90.8-1.10.7-0.60.90.6-1.10.40.71.0-0.70.4-0.40.4-0.2-0.40.8-0.0
Pavlov. Cond. response bias0.20.20.6-0.7-0.50.5-0.50.5-0.4-0.6-0.60.4-0.70.4-0.00.50.2-0.70.00.20.7-0.50.1-0.10.00.1-0.00.8-0.4
Pavlov. Cond. lever latency0.60.92.61.00.8-1.00.8-1.01.30.80.8-0.81.3-0.70.7-1.4-0.71.6-0.2-0.9-1.61.0-0.2-0.2-0.20.20.4-1.2-0.6
Pavlov. Cond. magazine entry latency3.64.26.7-2.4-2.22.3-2.22.3-2.3-2.2-2.22.3-2.32.2-2.12.22.2-2.11.82.12.0-2.61.8-1.61.7-1.7-1.80.8-0.9
Pavlov. Cond. change in total contacts2.02.87.2-2.1-1.62.0-1.62.1-2.1-1.6-1.61.4-2.51.6-1.42.31.1-2.60.51.22.7-1.90.4-0.00.3-0.3-0.42.5-0.2
Pavlov. Cond. index score2.63.36.3-2.2-1.92.1-1.92.2-2.3-1.9-1.91.8-2.51.9-1.72.41.7-2.51.11.72.5-2.31.1-0.60.9-1.0-1.21.7-0.1
Pavlov. Cond. latency score2.22.75.7-1.9-1.61.9-1.61.9-2.1-1.6-1.61.6-2.21.6-1.52.21.5-2.40.91.62.4-2.10.9-0.40.8-0.8-1.01.60.2
Pavlov. Cond. lever contacts0.60.81.8-1.2-0.91.0-0.91.1-1.1-0.9-0.90.8-1.30.8-0.91.10.7-1.30.30.61.3-1.20.3-0.10.2-0.3-0.41.30.0
Pavlov. Cond. magazine entry number6.17.511.03.33.0-3.23.0-3.23.12.92.9-2.93.3-3.02.6-3.1-2.73.2-2.3-2.6-3.03.3-2.21.8-2.02.12.1-1.61.0
Pavlov. Cond. intertrial magazine entries0.91.22.31.11.2-1.21.2-1.31.21.01.0-1.21.1-1.20.4-1.0-1.11.1-1.2-1.1-0.91.3-1.10.9-1.11.31.2-0.11.5
Pavlov. Cond. lever-magazine prob. diff.3.13.96.7-2.4-2.12.3-2.12.3-2.4-2.1-2.12.0-2.62.1-1.92.51.9-2.61.31.92.5-2.41.3-0.91.2-1.2-1.41.6-0.2
Pavlov. Cond. response bias1.92.64.7-2.0-1.71.9-1.71.9-1.9-1.7-1.71.6-2.21.6-1.62.01.5-2.11.01.42.1-2.01.0-0.70.9-1.0-1.01.5-0.4
Time in closed arm before self-admin0.50.54.5-0.6-0.20.4-0.20.5-0.6-0.2-0.20.2-0.90.2-1.00.90.2-0.9-0.30.31.10.0-0.20.5-0.40.50.41.32.1
Time in closed arm after self-admin0.20.21.10.70.6-0.50.5-0.50.20.50.5-0.40.8-0.20.5-0.6-0.40.70.1-0.1-0.70.60.10.10.20.0-0.2-1.00.2
Time in open arm before self-admin1.41.57.61.50.7-1.30.6-1.41.40.70.7-0.72.0-0.81.0-1.8-0.42.10.1-0.6-2.30.60.3-0.70.5-0.7-0.5-2.8-1.0
Time in open arm after self-admin0.20.20.70.10.1-0.30.3-0.40.80.10.1-0.20.4-0.40.3-0.8-0.10.8-0.2-0.6-0.8-0.1-0.1-0.5-0.1-0.10.3-0.3-0.2
Bone: periosteal estimation0.40.73.5-0.00.20.10.20.2-0.80.20.2-0.1-0.7-0.10.01.3-0.2-1.5-0.60.61.70.2-0.71.6-0.81.00.31.31.9
Bone: periosteal perimeter0.40.62.7-0.5-0.20.5-0.20.7-1.0-0.2-0.20.2-1.00.3-0.81.40.2-1.5-0.20.71.7-0.3-0.31.0-0.30.50.01.31.4
Bone: post-yield work1.72.39.6-0.6-0.30.9-0.31.2-2.1-0.3-0.30.3-1.60.3-0.92.60.3-2.7-0.41.33.1-0.1-0.72.2-0.70.90.12.53.1
Progressive ratio test 1 active lever presses3.13.24.51.82.1-1.82.1-1.71.72.12.1-2.11.5-1.91.5-1.5-1.91.3-2.0-1.9-1.11.9-2.02.0-2.01.81.90.50.5
Progressive ratio test 1 breakpoint2.72.84.01.72.0-1.72.0-1.61.71.91.9-2.01.4-1.81.2-1.4-1.81.2-1.9-1.8-1.01.8-1.91.8-1.91.71.80.50.7
Progressive ratio test 1 inactive lever presses1.21.33.91.31.4-1.31.4-1.31.31.31.3-1.31.3-1.22.0-1.2-1.11.0-1.1-1.1-1.00.5-1.00.9-0.90.80.8-0.4-0.4
Progressive ratio test 2 active lever presses4.65.08.22.02.5-2.12.5-2.01.92.52.5-2.51.5-2.42.4-1.3-2.51.0-2.7-2.2-0.62.1-2.82.9-2.82.82.71.40.5
Progressive ratio test 2 breakpoint5.86.69.42.42.9-2.52.9-2.42.52.92.9-2.91.9-2.82.8-2.0-3.01.6-3.0-2.8-1.22.5-3.12.8-3.13.03.01.10.3
Progressive ratio test 2 inactive lever presses8.19.314.12.83.5-3.03.5-2.92.93.43.4-3.52.2-3.43.7-2.1-3.41.5-3.8-3.1-1.12.3-3.73.6-3.73.73.51.51.1
Incentive Sensitization - Responses0.80.82.30.50.8-0.60.8-0.60.50.90.9-0.80.1-0.81.5-0.1-1.0-0.2-1.1-0.70.40.5-1.21.2-1.31.31.21.1-0.5
Incentive Sensitization - Breakpoint1.11.13.00.61.0-0.81.0-0.70.71.11.1-1.00.3-1.01.7-0.3-1.2-0.1-1.3-1.00.20.7-1.41.4-1.51.51.41.2-0.4
Sum of active levers in priming session hrs 5-61.81.87.0-2.0-1.21.7-1.21.8-1.3-1.1-1.11.0-2.21.2-0.61.40.7-1.70.40.31.8-1.40.2-0.4-0.10.00.32.6-1.6
Progressive ratio2.52.95.7-1.6-1.71.8-1.71.9-2.2-1.8-1.81.7-1.91.8-2.42.31.7-2.11.42.12.1-1.61.3-0.41.2-1.1-1.40.8-0.3
Food seeking constrained by brief footshock0.20.31.5-0.0-0.40.0-0.4-0.00.0-0.4-0.40.50.20.4-0.3-0.10.50.30.70.5-0.5-0.20.8-0.90.8-0.8-0.8-1.2-0.4
Seeking ratio, punishment vs. effort2.42.96.71.81.5-2.01.5-2.12.31.61.6-1.52.2-1.72.4-2.5-1.52.5-1.0-1.7-2.61.6-0.7-0.1-0.70.60.8-1.90.2
Retroperitoneal fat weight4.916.021.34.54.5-4.54.6-4.33.84.54.5-4.53.8-4.64.4-3.1-4.42.8-4.5-3.6-2.33.5-4.34.5-4.14.33.80.13.0
Reaction time number correct0.30.41.1-0.7-0.70.6-0.70.6-0.6-0.7-0.70.7-0.50.4-0.40.30.6-0.30.70.40.2-0.90.7-0.80.7-0.5-0.5-0.1-1.1
Reaction time mean minus median3.34.47.7-2.5-2.12.6-2.12.6-2.7-2.1-2.12.1-2.82.0-2.72.62.1-2.61.41.92.7-2.01.3-0.81.2-1.2-1.22.0-0.6
Reaction time mean minus median AUC1.82.45.4-1.9-1.51.9-1.51.8-1.8-1.6-1.61.5-1.91.4-2.31.71.8-1.71.11.31.6-1.61.1-0.91.0-1.0-0.91.4-0.7
Reaction time num false alarms0.91.25.11.20.6-1.00.6-1.11.00.80.8-0.61.7-0.81.1-1.7-0.51.90.3-0.7-2.10.60.3-0.70.6-0.6-0.3-2.3-1.4
Reaction time num false alarms AUC0.60.84.40.5-0.1-0.3-0.1-0.40.40.10.10.11.0-0.10.5-1.00.21.30.9-0.0-1.5-0.10.9-1.21.1-1.1-0.9-2.1-1.5
Reaction time trials correct on left0.30.41.1-0.7-0.70.6-0.70.6-0.6-0.7-0.70.7-0.50.4-0.40.30.6-0.30.70.40.2-0.90.7-0.80.7-0.5-0.5-0.1-1.1
Reaction time trials on left0.30.51.4-0.8-0.70.7-0.70.7-0.7-0.8-0.80.7-0.60.5-0.50.30.7-0.30.80.50.2-0.90.8-0.90.8-0.6-0.6-0.1-1.2
Reaction time mean0.20.32.0-0.5-0.00.5-0.00.5-0.4-0.1-0.10.0-0.7-0.0-0.80.60.3-0.7-0.3-0.00.9-0.3-0.30.5-0.30.20.41.4-0.3
Reaction time mean AUC0.20.32.3-0.40.00.40.10.5-0.4-0.0-0.0-0.0-0.7-0.1-0.90.60.2-0.7-0.4-0.10.9-0.3-0.40.6-0.50.30.51.5-0.1
Median of all reaction times0.20.21.30.10.5-0.10.50.00.10.40.4-0.4-0.2-0.5-0.10.2-0.2-0.3-0.6-0.40.50.0-0.70.8-0.60.40.61.1-0.1
Reaction time omissions0.91.22.9-1.2-0.91.4-0.91.4-1.3-0.9-0.91.1-1.11.0-1.20.91.5-0.81.10.80.7-1.51.0-0.91.1-1.3-1.00.6-1.7
Reaction time false alarm rate0.60.83.61.10.5-0.90.5-0.90.90.70.7-0.51.4-0.61.0-1.3-0.41.50.2-0.4-1.60.60.2-0.40.4-0.4-0.3-1.9-0.6
Reaction time premature initiation rate2.43.27.0-1.3-2.01.6-1.81.5-1.5-1.8-1.82.0-0.81.8-0.30.91.9-0.72.61.90.3-1.12.6-2.42.6-2.4-2.4-1.8-1.6
Reaction time premature initiations3.55.09.6-2.0-2.52.2-2.42.1-1.9-2.4-2.42.5-1.42.3-0.91.12.4-0.93.02.20.5-1.73.0-3.13.1-2.8-2.7-1.5-2.2
Std. dev. reaction times0.81.22.7-1.4-1.01.4-1.01.5-1.4-0.9-0.90.9-1.50.9-1.71.31.1-1.30.60.71.4-0.80.4-0.20.4-0.5-0.31.6-0.8
Reaction time trials completed0.30.51.4-0.8-0.70.7-0.70.7-0.7-0.8-0.80.7-0.60.5-0.50.30.7-0.30.80.50.2-0.90.8-0.90.8-0.6-0.6-0.1-1.2
Reaction time trials AUC0.20.30.9-0.5-0.50.5-0.50.5-0.5-0.6-0.60.6-0.30.3-0.30.20.5-0.10.70.40.0-0.80.7-0.80.7-0.5-0.5-0.3-1.0
Run reversals in cocaine runway, females0.70.74.00.2-0.50.2-0.50.1-0.7-0.3-0.30.70.30.60.30.30.7-0.11.11.3-0.1-0.51.3-0.71.4-1.2-1.6-2.00.4
Run reversals in cocaine runway, males0.30.31.80.40.6-0.60.6-0.60.70.10.1-0.30.5-0.6-0.8-0.4-0.20.5-0.5-0.3-0.50.5-0.30.1-0.30.50.4-0.31.3
Latency to leave start box in cocaine runway0.10.10.60.40.2-0.20.2-0.1-0.10.30.3-0.30.1-0.2-0.10.3-0.3-0.3-0.30.10.40.8-0.40.8-0.40.40.20.20.6
Latency to leave start box in cocaine runway, F0.10.10.5-0.1-0.20.1-0.20.2-0.1-0.1-0.10.0-0.20.1-0.00.3-0.1-0.3-0.10.00.40.2-0.20.2-0.30.10.10.5-0.7
Latency to leave start box in cocaine runway, M0.30.33.10.50.3-0.30.3-0.2-0.10.50.5-0.30.3-0.3-0.80.1-0.20.1-0.10.10.10.9-0.20.7-0.10.30.2-0.11.8
Std. dev. time between licks in bursts0.50.63.90.80.3-0.70.3-0.80.70.50.5-0.21.2-0.50.5-1.1-0.11.30.4-0.2-1.50.40.6-0.80.7-0.6-0.4-2.0-0.3
Total sessions with >9 infusions1.82.04.02.01.8-1.71.8-1.71.21.81.8-1.71.7-1.61.0-0.9-1.31.1-1.4-0.9-0.90.9-1.31.9-1.11.10.8-0.71.0
Short access day 1 total inactive lever presses4.44.98.82.62.6-2.52.6-2.42.22.62.6-2.62.4-2.43.0-2.1-2.51.9-2.2-2.2-1.71.9-2.22.1-2.02.01.9-0.50.0
Short access day 10 total inactive lever presses3.84.26.92.52.1-2.42.1-2.42.52.22.2-2.22.6-2.22.3-2.5-2.22.5-1.7-2.1-2.52.0-1.51.1-1.31.31.3-1.60.3
Short access day 1 total infusions2.82.94.92.22.1-1.92.1-1.91.42.22.2-2.01.9-1.82.0-1.2-1.81.2-1.7-1.3-1.01.5-1.72.2-1.61.51.3-0.31.1
Short access day 10 total infusions1.61.85.51.81.6-1.41.6-1.30.61.61.6-1.51.2-1.41.7-0.3-1.40.3-1.4-0.6-0.11.0-1.52.3-1.41.51.00.21.4
Short access total infusions1.41.63.61.81.5-1.41.5-1.30.81.61.6-1.51.4-1.31.5-0.6-1.20.7-1.2-0.6-0.50.9-1.21.9-1.01.10.7-0.31.1
Short access day 1 locomotion2.02.15.11.91.7-1.81.7-1.81.31.91.9-1.61.6-1.72.3-0.9-1.50.8-1.5-0.8-0.70.5-1.41.9-1.21.30.8-0.60.8
Short access day 10 total locomotion1.41.64.11.51.4-1.51.4-1.51.11.51.5-1.41.2-1.52.0-0.7-1.40.6-1.4-0.8-0.50.7-1.31.6-1.21.30.9-0.31.0
Short access total locomotion1.41.55.11.61.4-1.51.4-1.40.91.51.5-1.31.3-1.32.3-0.7-1.30.6-1.1-0.6-0.50.5-1.11.6-0.91.00.6-0.61.2
One hour access (0.3 mA shock)9.410.915.43.33.7-3.53.7-3.43.33.73.7-3.82.7-3.83.5-2.6-3.72.2-3.9-3.4-1.73.0-3.83.7-3.83.83.50.90.9
Compulsive drug intake2.82.88.2-1.3-1.91.4-1.91.3-0.9-1.8-1.81.8-0.51.7-1.10.11.70.12.21.2-0.6-1.02.4-2.92.5-2.4-2.1-1.9-1.7
One hour access (shock baseline)8.710.118.02.83.7-3.03.7-2.92.73.73.7-3.61.9-3.52.7-1.7-3.41.3-4.0-3.2-0.72.6-4.24.2-4.24.03.92.41.2
Social response proportion0.91.01.5-1.2-1.11.2-1.21.2-1.0-1.1-1.11.1-1.20.9-0.81.21.2-1.10.91.01.1-1.00.8-0.60.7-0.8-0.70.8-0.2
Social responses0.40.51.3-0.8-0.70.7-0.80.6-0.4-1.1-1.10.8-0.60.5-1.00.30.9-0.20.70.50.1-1.10.8-1.00.7-0.7-0.4-0.00.1
Social time0.40.61.6-0.6-0.60.7-0.70.6-0.6-0.9-0.90.8-0.40.4-1.30.31.0-0.20.90.60.1-1.10.9-0.90.9-1.0-0.7-0.3-0.5
Soleus weight3.711.014.63.83.8-3.73.8-3.63.53.73.7-3.73.6-3.73.0-3.3-3.53.3-3.3-3.3-3.03.7-3.22.8-3.03.03.0-0.61.5
Bone: stiffness2.84.49.1-2.2-2.02.4-2.02.5-2.9-2.0-2.02.0-2.62.1-2.42.92.0-3.01.52.33.0-2.01.2-0.31.1-1.1-1.51.80.8
Tibialis anterior weight10.034.043.4-6.5-6.46.6-6.56.5-6.5-6.5-6.56.5-6.26.5-5.75.96.3-5.75.96.05.1-6.55.7-4.85.5-5.1-5.41.3-1.5
Time to tail flick, vehicle, before self-admin0.91.02.8-0.8-1.01.0-0.91.0-1.4-0.9-0.90.9-1.10.8-0.61.60.8-1.60.71.41.7-0.70.60.20.5-0.4-0.80.60.6
Time to tail flick, vehicle, after self-admin2.32.45.5-1.2-1.51.1-1.71.0-1.4-1.7-1.71.8-1.11.3-1.81.71.8-1.31.62.41.1-1.51.9-1.21.8-1.5-2.0-1.01.5
Time to tail flick, test, before self-admin0.80.71.81.30.9-1.21.0-1.20.61.01.0-0.81.2-0.81.2-0.4-0.80.5-0.5-0.0-0.50.3-0.40.9-0.30.70.1-1.21.4
Time to tail flick, test, after self-admin0.10.10.6-0.2-0.20.2-0.10.1-0.1-0.4-0.40.3-0.20.1-0.80.30.3-0.20.10.30.1-0.50.2-0.20.2-0.3-0.10.00.7
Delta time to tail flick, vehicle, before/after SA0.70.62.0-0.5-0.70.4-0.80.3-0.5-0.9-0.90.9-0.30.6-1.40.51.0-0.20.91.10.1-0.71.0-1.01.0-0.9-1.0-0.90.6
Delta time to tail flick, test, before/after SA1.31.22.5-1.6-1.21.5-1.11.4-0.7-1.3-1.31.1-1.41.2-1.40.61.1-0.60.90.30.6-0.80.8-1.30.7-1.2-0.41.1-1.3
Tibia length1.33.79.7-2.5-1.92.3-1.82.4-2.2-1.9-1.91.6-3.01.9-1.32.61.2-3.00.61.33.1-1.70.4-0.10.2-0.2-0.33.1-0.4
Ambulatory time before self-admin0.80.83.7-1.1-0.61.0-0.61.0-1.1-0.6-0.60.6-1.50.6-0.21.20.3-1.50.10.41.6-1.0-0.20.3-0.30.30.31.90.2
Ambulatory time after self-admin0.30.41.6-0.00.4-0.10.4-0.00.10.40.4-0.4-0.3-0.30.60.2-0.6-0.5-0.7-0.40.60.1-0.80.9-0.80.90.91.30.9
Bone: tissue strength0.10.10.6-0.2-0.00.2-0.00.2-0.20.00.0-0.1-0.3-0.0-0.20.10.0-0.2-0.2-0.20.3-0.0-0.30.3-0.30.20.40.8-0.0
Total heroin consumption5.16.08.2-2.9-2.72.8-2.72.8-2.6-2.7-2.72.8-2.62.8-2.52.32.8-2.12.52.41.9-2.82.4-2.32.2-2.3-2.20.7-0.8
Bone: trabecular number0.71.14.1-1.0-0.91.0-0.91.1-1.5-0.8-0.80.8-1.50.9-0.41.80.6-1.90.31.22.0-1.00.20.50.1-0.1-0.51.40.4
Bone: trabecular spacing0.50.72.80.80.5-0.80.5-0.91.00.50.5-0.51.2-0.60.4-1.4-0.31.6-0.0-0.8-1.70.70.1-0.60.2-0.00.1-1.4-0.0
Bone: trabecular thickness0.50.61.70.80.8-0.80.8-0.70.40.90.9-0.90.5-0.80.8-0.2-1.00.2-0.9-0.6-0.00.6-1.01.3-1.00.90.90.40.5
Bone: trabecular tissue density3.14.35.92.12.3-2.22.3-2.22.42.32.3-2.32.0-2.31.5-2.2-2.22.1-2.4-2.4-1.92.1-2.21.7-2.22.02.20.10.7
Water consumed over 24 hours0.70.92.2-1.1-1.11.0-1.11.0-0.6-1.1-1.11.0-0.81.0-0.50.31.1-0.31.10.50.1-0.91.1-1.51.1-1.1-0.8-0.1-1.3
Number of responses in last shaping day1.41.55.61.31.3-1.41.3-1.41.51.31.3-1.21.5-1.22.4-1.5-1.11.4-1.0-1.2-1.50.4-0.80.5-0.70.60.7-0.9-0.2