Hub : Traits : Tibialis anterior weight : ← : →

chr11:32,148,992-35,008,541

Trait: Tibialis anterior weight

Best TWAS P=3.21e-09 · Best GWAS P=2.59e-09 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Cbr1	alternative polyA	ENSRNOT00000075105	0.32	10	0.26	3.6e-29	5.15	2.59e-07	0.68	FALSE
Adipose	Cbr1	alternative polyA	ENSRNOT00000075985	0.32	10	0.27	1.7e-29	-5.16	2.52e-07	0.68	FALSE
Adipose	Ttc3	gene expression	ENSRNOG00000001682	0.32	53	0.36	8.4e-42	5.4	6.54e-08	0.59	FALSE
Adipose	Ripply3	gene expression	ENSRNOG00000001684	0.02	1	0.02	2.0e-03	-5.76	8.54e-09	0.04	FALSE
Adipose	Setd4	gene expression	ENSRNOG00000001699	0.57	83	0.51	3.6e-65	5.15	2.60e-07	0.67	FALSE
Adipose	ENSRNOG00000067486	gene expression	ENSRNOG00000067486	0.24	17	0.23	8.0e-25	5.34	9.42e-08	0	TRUE
Adipose	Ttc3	intron excision ratio	chr11:33702457:33703457	0.02	1	0.02	3.5e-03	5.76	8.54e-09	0.04	FALSE
BLA	Setd4	gene expression	ENSRNOG00000001699	0.41	20	0.29	4.2e-16	5.78	7.61e-09	0.68	FALSE
BLA	Sim2	gene expression	ENSRNOG00000054203	0.05	1	0.04	3.7e-03	-5.57	2.54e-08	0.04	FALSE
BLA	U4	gene expression	ENSRNOG00000061658	0.06	1	0.04	5.8e-03	5.57	2.56e-08	0.05	FALSE
BLA	ENSRNOG00000067486	gene expression	ENSRNOG00000067486	0.19	2012	0.22	2.9e-12	5.17	2.36e-07	0.45	FALSE
BLA	Cbr1	isoform ratio	ENSRNOT00000042283	0.47	1975	0.37	1.1e-20	5.63	1.83e-08	0.69	FALSE
BLA	Cbr1	isoform ratio	ENSRNOT00000072384	0.07	1975	0.02	4.1e-02	-5.26	1.42e-07	0.4	FALSE
BLA	Ttc3	intron excision ratio	chr11:33721965:33734534	0.06	1	0.06	6.1e-04	5.79	7.05e-09	0.06	FALSE
BLA	Setd4	intron excision ratio	chr11:32845874:32847402	0.08	1	0.03	9.6e-03	5.6	2.13e-08	0.05	FALSE
BLA	Cbr1	intron excision ratio	chr11:32860952:32861423	0.14	1975	0.13	1.2e-07	5.22	1.83e-07	0.58	FALSE
BLA	Vps26c	mRNA stability	ENSRNOG00000001681	0.14	1882	0.12	4.7e-07	-5.13	2.92e-07	0.31	FALSE
Brain	Kcnj6	alternative polyA	ENSRNOT00000066940	0.57	235	0.39	1.9e-38	-5.11	3.27e-07	0.7	TRUE
Brain	Kcnj6	alternative polyA	ENSRNOT00000119355	0.57	238	0.39	4.1e-38	5.11	3.25e-07	0.7	FALSE
Brain	Setd4	gene expression	ENSRNOG00000001699	0.44	95	0.45	3.0e-45	5.5	3.71e-08	0.68	FALSE
Brain	Cbr1	gene expression	ENSRNOG00000049911	0.71	60	0.71	5.0e-92	5.11	3.18e-07	0.35	FALSE
Brain	U4	gene expression	ENSRNOG00000061658	0.21	1	0.16	1.1e-14	5.53	3.21e-08	0.54	FALSE
Brain	ENSRNOG00000063617	gene expression	ENSRNOG00000063617	0.1	11	0.11	1.8e-10	-5.55	2.84e-08	0.69	FALSE
Brain	ENSRNOG00000067486	gene expression	ENSRNOG00000067486	0.29	2012	0.21	2.8e-19	5.49	4.00e-08	0.69	FALSE
Brain	Kcnj6	isoform ratio	ENSRNOT00000079955	0.32	1	0.03	2.1e-03	-5.76	8.33e-09	0.06	FALSE
Brain	Setd4	isoform ratio	ENSRNOT00000002308	0.07	40	0.05	3.9e-05	-5.6	2.12e-08	0.65	FALSE
Brain	Setd4	isoform ratio	ENSRNOT00000104229	0.07	32	0.05	2.6e-05	5.62	1.95e-08	0.66	TRUE
Brain	Cbr1	isoform ratio	ENSRNOT00000042283	0.52	76	0.5	1.7e-52	5.52	3.39e-08	0.68	FALSE
Brain	Cbr1	isoform ratio	ENSRNOT00000114595	0.2	1	0.21	2.1e-19	-5.65	1.60e-08	0.7	FALSE
Brain	Kcnj6	intron excision ratio	chr11:34250394:34308566	0.06	15	0.04	7.1e-05	5.27	1.39e-07	0.49	TRUE
Brain	Kcnj6	intron excision ratio	chr11:34276411:34308566	0.04	2461	0.03	1.7e-03	-5.59	2.21e-08	0.58	FALSE
Brain	Ttc3	intron excision ratio	chr11:33721965:33734534	0.16	28	0.18	2.7e-16	5.31	1.10e-07	0.63	FALSE
Brain	Setd4	intron excision ratio	chr11:32845874:32847402	0.08	1972	0.05	2.7e-05	5.16	2.45e-07	0.68	FALSE
Brain	Setd4	intron excision ratio	chr11:32845874:32853438	0.43	38	0.08	5.0e-08	-5.12	3.03e-07	0.33	FALSE
Brain	Setd4	intron excision ratio	chr11:32847490:32850712	0.06	1972	0.06	4.1e-06	5.41	6.19e-08	0.66	FALSE
Brain	Cbr1	intron excision ratio	chr11:32877739:32878644	0.15	1975	0.18	4.0e-16	5.31	1.10e-07	0.67	FALSE
Brain	Cbr1	intron excision ratio	chr11:32893820:32894725	0.13	11	0.15	3.9e-14	-5.69	1.28e-08	0.69	FALSE
Brain	Kcnj6	mRNA stability	ENSRNOG00000001658	0.39	14	0.17	1.8e-15	5.76	8.33e-09	0.71	FALSE
Brain	Vps26c	mRNA stability	ENSRNOG00000001681	0.06	18	0.04	5.1e-05	-5.92	3.21e-09	0.58	TRUE
Brain	Setd4	mRNA stability	ENSRNOG00000001699	0.11	1	0.06	2.4e-06	-5.59	2.27e-08	0.44	FALSE
Eye	Vps26c	intron excision ratio	chr11:33826532:33827030	0.34	1	0.01	2.0e-01	5.63	1.79e-08	0.06	FALSE
IL	Cbr1	alternative polyA	ENSRNOT00000075105	0.17	1972	0.04	4.2e-02	5.38	7.53e-08	0.46	FALSE
IL	Cbr1	alternative polyA	ENSRNOT00000075985	0.16	1972	0.03	5.6e-02	-5.36	8.55e-08	0.43	FALSE
IL	Cbr1	alternative polyA	ENSRNOT00000072384	0.13	1	0.16	9.6e-05	5.65	1.60e-08	0.06	FALSE
IL	Cbr1	alternative polyA	ENSRNOT00000114595	0.13	1	0.17	8.9e-05	-5.65	1.60e-08	0.06	TRUE
IL	Setd4	gene expression	ENSRNOG00000001699	0.53	5	0.41	5.2e-11	5.65	1.61e-08	0.69	FALSE
IL	Cbr1	gene expression	ENSRNOG00000049911	0.64	14	0.56	5.8e-16	5.15	2.58e-07	0.45	FALSE
IL	Cbr1	isoform ratio	ENSRNOT00000042283	0.46	7	0.27	4.0e-07	5.58	2.43e-08	0.67	FALSE
IL	Cbr1	isoform ratio	ENSRNOT00000072384	0.28	1	0.22	6.7e-06	-5.63	1.77e-08	0.1	FALSE
IL	Setd4	intron excision ratio	chr11:32845874:32847402	0.13	1	0.12	8.4e-04	5.68	1.37e-08	0.06	FALSE
IL	Setd4	intron excision ratio	chr11:32845874:32853438	0.15	1	0.11	1.2e-03	-5.68	1.37e-08	0.07	FALSE
LHb	Ripply3	gene expression	ENSRNOG00000001684	0.13	1884	0.04	4.5e-02	-5.66	1.48e-08	0.41	FALSE
LHb	Setd4	gene expression	ENSRNOG00000001699	0.32	1969	0.3	8.8e-08	5.22	1.83e-07	0.66	FALSE
LHb	Cbr1	isoform ratio	ENSRNOT00000042283	0.41	44	0.38	7.0e-10	5.38	7.65e-08	0.68	FALSE
LHb	Vps26c	mRNA stability	ENSRNOG00000001681	0.14	1874	0.11	1.3e-03	-5.58	2.45e-08	0.46	FALSE
Liver	Cldn14	alternative TSS	ENSRNOT00000002297	0.29	17	0.3	5.4e-34	-5.64	1.69e-08	0.66	FALSE
Liver	Cldn14	alternative TSS	ENSRNOT00000102693	0.28	17	0.3	1.4e-33	5.64	1.67e-08	0.66	FALSE
Liver	Ripply3	gene expression	ENSRNOG00000001684	0.04	1890	0.03	3.6e-04	-5.55	2.84e-08	0.63	FALSE
Liver	Cldn14	gene expression	ENSRNOG00000001691	0.03	21	0.02	4.7e-03	5.53	3.24e-08	0.45	FALSE
Liver	Setd4	gene expression	ENSRNOG00000001699	0.29	41	0.27	1.8e-29	5.65	1.62e-08	0.69	FALSE
Liver	Cbr3	gene expression	ENSRNOG00000001701	0.04	1942	0.02	2.4e-03	-5.24	1.61e-07	0.6	FALSE
Liver	Dop1b	gene expression	ENSRNOG00000051204	0.07	1	0.06	2.5e-07	5.63	1.77e-08	0.67	FALSE
Liver	Cldn14	isoform ratio	ENSRNOT00000002297	0.29	8	0.31	3.2e-35	-5.65	1.57e-08	0.65	FALSE
Liver	Cldn14	isoform ratio	ENSRNOT00000102693	0.29	1	0.32	6.6e-36	5.66	1.49e-08	0.63	FALSE
Liver	Cldn14	intron excision ratio	chr11:33233296:33241680	0.05	1	0.04	1.0e-05	-5.57	2.56e-08	0.35	FALSE
Liver	Cldn14	intron excision ratio	chr11:33233296:33242036	0.16	25	0.12	4.3e-13	5.37	7.94e-08	0.66	FALSE
Liver	Vps26c	mRNA stability	ENSRNOG00000001681	0.07	1881	0.07	2.0e-08	-5.48	4.26e-08	0.45	FALSE
NAcc	Hlcs	gene expression	ENSRNOG00000001686	0.04	6	0.04	3.4e-04	-5.66	1.53e-08	0.56	FALSE
NAcc	Setd4	gene expression	ENSRNOG00000001699	0.36	29	0.39	1.2e-30	5.72	1.09e-08	0.7	FALSE
NAcc	Cbr1	gene expression	ENSRNOG00000049911	0.67	82	0.77	8.0e-88	5.19	2.13e-07	0.27	FALSE
NAcc	ENSRNOG00000063617	gene expression	ENSRNOG00000063617	0.07	1	0.05	7.8e-05	-5.76	8.24e-09	0.22	FALSE
NAcc	Setd4	isoform ratio	ENSRNOT00000002308	0.04	1	0.04	5.4e-04	-5.3	1.13e-07	0.07	FALSE
NAcc	Setd4	isoform ratio	ENSRNOT00000104229	0.04	1	0.03	1.5e-03	5.3	1.13e-07	0.07	FALSE
NAcc	Cbr1	isoform ratio	ENSRNOT00000042283	0.49	101	0.48	4.2e-40	5.26	1.46e-07	0.72	FALSE
NAcc	Cbr1	isoform ratio	ENSRNOT00000072384	0.09	1	0.1	1.2e-07	-5.52	3.43e-08	0.52	FALSE
NAcc	Cbr1	isoform ratio	ENSRNOT00000114595	0.13	1974	0.15	2.8e-11	-5.62	1.87e-08	0.71	FALSE
NAcc	Ttc3	intron excision ratio	chr11:33721965:33734534	0.03	1971	0.03	1.8e-03	5.57	2.53e-08	0.51	FALSE
NAcc	Setd4	intron excision ratio	chr11:32847490:32850712	0.04	1971	0.03	2.7e-03	5.32	1.03e-07	0.58	FALSE
NAcc	Cbr1	intron excision ratio	chr11:32877739:32878644	0.04	1974	0.01	1.0e-01	5.67	1.43e-08	0.64	FALSE
NAcc	Vps26c	mRNA stability	ENSRNOG00000001681	0.09	23	0.1	1.4e-07	-5.41	6.41e-08	0.5	FALSE
OFC	Setd4	gene expression	ENSRNOG00000001699	0.33	1	0.26	8.2e-07	5.63	1.82e-08	0.29	FALSE
OFC	Cbr1	isoform ratio	ENSRNOT00000042283	0.45	8	0.37	1.1e-09	5.22	1.83e-07	0.54	FALSE
OFC	Cbr1	isoform ratio	ENSRNOT00000072384	0.13	1972	0.07	8.3e-03	-5.34	9.22e-08	0.35	FALSE
PL	Hlcs	alternative TSS	ENSRNOT00000002291	0.04	1814	0.01	5.3e-02	5.15	2.62e-07	0.52	FALSE
PL	Hlcs	alternative TSS	ENSRNOT00000002291	0.04	1814	0.01	5.9e-02	5.25	1.49e-07	0.53	FALSE
PL	Hlcs	alternative TSS	ENSRNOT00000099969	0.03	1814	0.01	9.5e-02	-5.3	1.17e-07	0.54	FALSE
PL	Hlcs	gene expression	ENSRNOG00000001686	0.08	32	0.06	5.3e-05	-5.38	7.56e-08	0.58	FALSE
PL	Setd4	gene expression	ENSRNOG00000001699	0.45	11	0.35	2.3e-27	5.84	5.16e-09	0.71	FALSE
PL	Dop1b	gene expression	ENSRNOG00000051204	0.05	1864	0.06	3.4e-05	5.1	3.42e-07	0.51	FALSE
PL	U4	gene expression	ENSRNOG00000061658	0.05	1	0.04	4.6e-04	5.63	1.75e-08	0.07	FALSE
PL	Cbr1	isoform ratio	ENSRNOT00000072384	0.08	1	0.06	2.7e-05	-5.53	3.21e-08	0.48	FALSE
PL	Cbr1	isoform ratio	ENSRNOT00000114595	0.12	1974	0.1	6.5e-08	-5.46	4.77e-08	0.69	FALSE
PL	Ttc3	intron excision ratio	chr11:33721965:33734534	0.09	27	0.09	3.2e-07	5.63	1.82e-08	0.53	FALSE
PL	Ttc3	intron excision ratio	chr11:33727139:33728112	0.04	1	0.03	3.1e-03	-5.65	1.60e-08	0.05	FALSE
PL	Setd4	intron excision ratio	chr11:32845874:32847402	0.03	1971	0.02	1.2e-02	5.21	1.84e-07	0.47	FALSE
PL	Morc3	intron excision ratio	chr11:33163168:33163995	0.04	1	0.04	9.0e-04	-5.82	5.93e-09	0.15	FALSE
PL	Vps26c	mRNA stability	ENSRNOG00000001681	0.12	1881	0.13	2.9e-10	-5.63	1.82e-08	0.59	FALSE