Hub : Genes

Rps6ka4

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability Rps6ka4 0.03 0.02 6.6e-03 0.01 0 -0 0 5.6e-02 8.8e-02 6.0e-01 2.4e-01
2 Liver mRNA stability Rps6ka4 0.06 0.04 3.8e-05 0.04 0.03 0.03 0.04 1.9e-05 3.0e-04 1.8e-04 5.5e-05
3 Adipose gene expression Rps6ka4 0.05 0.04 2.4e-03 0.01 0.01 0.01 0.01 2.4e-02 4.7e-02 3.2e-02 6.4e-02
4 OFC gene expression Rps6ka4 0.17 0.1 2.0e-03 0.06 0.08 0.07 0.07 1.4e-02 6.7e-03 1.1e-02 1.2e-02
5 Brain mRNA stability Rps6ka4 0.03 0.02 6.2e-03 0.01 0.02 0.01 0.01 3.6e-02 6.3e-03 4.0e-02 3.1e-02
6 NAcc gene expression Rps6ka4 0.15 0.07 0.0e+00 0.1 0.12 0.12 0.12 1.2e-15 1.3e-17 6.8e-18 8.3e-18
7 BLA gene expression Rps6ka4 0.44 0.16 7.4e-14 0.24 0.24 0.24 0.25 7.5e-13 3.3e-13 6.2e-13 2.2e-13
8 IC gene expression Rps6ka4 0.17 0.1 8.8e-04 0.08 0.06 0.05 0.08 2.8e-04 1.5e-03 3.6e-03 4.0e-04
9 PL gene expression Rps6ka4 0.17 0.08 4.6e-12 0.1 0.1 0.1 0.1 3.3e-11 2.9e-11 4.8e-11 1.0e-10
10 Brain gene expression Rps6ka4 0.08 0.05 1.5e-04 0.04 0.04 0.04 0.03 1.8e-04 2.3e-04 1.0e-04 4.6e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.81.53.20.90.9-0.80.5-0.7-1.81.8-1.71.3-1.2
Area under the delay curve0.30.51.50.0-0.10.10.10.4-0.90.9-0.81.1-1.2
BMI with tail3.712.924.52.32.2-2.71.7-1.7-5.04.9-4.93.6-4.4
BMI without tail0.94.68.21.51.5-1.61.4-0.6-2.82.7-2.62.6-2.9
Body weight3.515.123.63.73.6-3.83.2-2.8-4.94.6-4.33.8-3.8
Weight adjusted by age0.41.32.91.71.4-1.41.5-1.7-0.70.5-0.30.20.1
Bone surface3.87.510.53.03.1-3.02.3-3.2-3.23.0-2.71.6-1.5
Bone volume1.53.05.11.81.8-1.71.0-2.1-2.32.1-2.10.8-0.9
Breakpoint value in progressive ratio session1.52.75.52.02.0-2.22.0-2.3-1.51.2-0.60.6-0.3
Number of licking bursts0.10.20.50.60.6-0.60.5-0.7-0.20.10.0-0.00.1
Context. condit. distance diff. score1.01.22.8-1.6-1.61.4-1.31.70.4-0.20.00.1-0.4
Locomotion velocity, session 10.40.41.50.10.1-0.00.10.5-0.70.8-0.61.2-0.9
Locomotion distance, session 11.31.63.30.80.8-0.50.40.1-1.71.8-1.81.8-1.5
Locomotion velocity, session 22.12.53.61.91.9-1.71.6-1.4-1.71.6-1.41.4-1.1
Locomotion distance, session 20.81.12.41.01.0-0.60.8-0.1-1.31.3-1.11.5-1.1
Locomotion velocity, session 31.82.04.9-0.5-0.50.8-1.01.2-1.51.8-2.21.6-1.9
Locomotion distance, session 30.20.20.6-0.2-0.20.1-0.20.4-0.50.5-0.80.5-0.7
Stereotopy head waving bouts, day 31.82.24.2-0.9-0.81.2-1.21.6-1.31.7-2.11.5-2.0
Stereotopy head waving duration, day 30.60.71.3-0.9-0.81.2-1.21.2-0.30.6-0.90.4-0.7
Locomotion velocity, session 70.91.02.7-0.7-0.60.9-1.01.0-0.81.0-1.70.7-1.2
Locomotion distance, session 70.60.81.7-0.2-0.20.4-0.20.9-0.91.1-1.31.3-1.3
Stereotopy head waving bouts, day 70.10.10.3-0.1-0.10.0-0.4-0.3-0.40.4-0.6-0.2-0.3
Stereotopy head waving duration, day 70.50.71.81.01.0-1.00.7-1.3-0.80.6-0.50.0-0.2
Locomotion velocity, session 81.01.22.61.11.1-1.11.2-0.4-1.11.1-0.61.6-1.1
Locomotion distance, session 80.71.12.2-0.5-0.50.5-0.80.9-1.11.3-1.51.2-1.4
Degree of sensitization distance0.60.61.4-0.0-0.00.3-0.30.6-0.91.1-1.21.1-1.2
Degree of sensitization stereotypy0.40.41.50.70.7-0.80.3-1.2-0.50.4-0.3-0.30.0
Conditioned locomotion1.11.32.31.31.5-1.31.3-1.0-1.01.0-0.61.0-0.8
Cocaine response after cond. corrected0.81.23.6-1.4-1.31.5-1.21.90.20.1-0.20.6-0.6
Cocaine response after cond. not corrected0.60.82.4-1.2-1.11.2-1.01.5-0.10.3-0.40.6-0.6
Cocaine response before conditioning0.60.72.31.00.9-1.20.9-1.5-0.30.1-0.1-0.50.6
Saline control response3.04.17.22.52.5-2.52.7-2.1-1.81.5-1.21.4-1.2
Bone: connectivity density2.43.85.92.02.0-2.01.6-1.8-2.42.3-2.01.6-1.3
Bone: cortical apparent density0.30.51.30.30.3-0.30.5-0.40.9-1.11.0-0.80.9
Bone: cortical area0.50.81.61.21.1-1.00.8-1.3-0.80.6-0.70.2-0.4
Bone: cortical porosity0.10.10.20.40.5-0.30.4-0.4-0.10.0-0.1-0.0-0.3
Bone: cortical porosity0.40.40.80.80.9-0.80.8-0.7-0.50.4-0.40.4-0.5
Bone: cortical thickness1.72.87.02.42.3-2.32.7-2.0-0.40.00.30.5-0.1
Bone: cortical thickness0.40.51.20.70.7-0.71.1-0.0-0.50.3-0.21.1-0.7
Bone: cortical tissue density0.40.61.20.40.5-0.50.7-0.60.9-1.11.0-0.80.9
Condit. Reinf. active minus inactive responses0.10.10.30.40.4-0.50.5-0.3-0.20.2-0.30.2-0.5
Condit. Reinf. active-inactive response ratio0.20.20.40.20.2-0.40.4-0.30.5-0.60.5-0.50.2
Condit. Reinf. active responses0.00.10.30.10.1-0.1-0.1-0.1-0.30.3-0.60.1-0.4
Condit. Reinf. inactive responses0.30.41.2-0.4-0.40.5-0.70.4-0.60.7-1.10.3-0.5
Incentive salience index mean0.40.51.00.50.6-0.60.5-0.4-0.80.8-1.00.6-1.0
Condit. Reinf. lever presses0.50.81.80.70.7-0.80.5-0.8-1.21.2-1.30.5-0.9
Condit. Reinf. active minus inactive responses0.10.10.5-0.3-0.20.3-0.6-0.20.0-0.1-0.3-0.70.2
Condit. Reinf. active-inactive response ratio0.40.62.3-1.0-0.80.9-1.50.3-0.10.2-0.8-0.80.0
Condit. Reinf. active responses0.10.10.40.30.4-0.40.1-0.7-0.1-0.0-0.1-0.40.1
Condit. Reinf. inactive responses0.30.51.50.90.8-1.01.2-0.6-0.2-0.00.30.4-0.3
Condit. Reinf. lever presses1.31.84.11.61.7-1.61.1-2.0-1.41.2-1.10.2-0.3
Condit. Reinf. lever reinforcers received0.20.31.10.60.7-0.70.5-1.0-0.20.0-0.1-0.50.2
Conditioned reinforcement - actives0.10.41.60.10.0-0.2-0.5-1.00.1-0.2-0.1-1.30.9
Conditioned reinforcement - inactives1.13.15.0-2.0-2.11.9-2.20.81.5-1.31.3-2.21.8
Conditioned locomotion5.78.512.7-3.3-3.43.5-3.62.52.9-2.52.0-2.62.2
Patch foraging indifference point 0 sec0.00.00.1-0.0-0.1-0.0-0.10.00.1-0.20.1-0.3-0.1
Patch foraging indifference point AUC1.02.35.91.91.8-2.41.7-2.4-0.70.3-0.4-0.30.6
Delay disc. indifference point, 0s delay1.21.32.9-0.3-0.40.1-0.31.0-1.41.5-1.41.7-1.7
Delay disc. indifference point, 16s delay0.30.50.9-0.9-0.90.9-0.90.60.5-0.50.3-0.60.3
Delay disc. indifference point, 2s delay0.20.20.4-0.2-0.30.2-0.40.3-0.60.6-0.50.7-0.7
Delay disc. indifference point, 24s delay0.00.00.1-0.1-0.20.10.30.40.1-0.10.10.2-0.2
Delay disc. indifference point, 4s delay0.70.72.0-0.2-0.20.10.20.7-1.01.0-0.91.4-1.4
Delay disc. indifference point, 8s delay0.30.51.70.0-0.00.20.20.6-0.80.9-0.71.2-1.3
Indifference point function ln k2.47.117.6-3.6-3.53.7-3.14.21.6-1.10.9-0.0-0.5
Indifference point function log k2.47.117.6-3.6-3.53.7-3.14.21.6-1.10.9-0.0-0.5
Patch foraging total patch changes 0 sec0.00.00.10.0-0.0-0.10.10.10.2-0.40.3-0.2-0.1
Patch foraging total patch changes 12 sec3.14.18.72.72.5-2.92.6-2.6-1.71.3-1.00.8-0.5
Patch foraging total patch changes 18 sec0.30.82.11.00.8-1.41.0-1.4-0.60.3-0.6-0.2-0.1
Patch foraging total patch changes 24 sec0.61.94.21.91.7-2.01.9-1.9-0.90.5-0.30.3-0.2
Patch foraging total patch changes 6 sec0.81.32.01.31.2-1.41.3-0.9-1.21.0-1.01.1-1.1
Patch foraging time to switch 0 sec0.72.84.91.71.6-1.11.0-1.5-2.12.2-2.21.3-1.5
Patch foraging water rate 0 sec1.65.98.0-2.8-2.72.4-2.12.32.8-2.82.5-2.01.6
Patch foraging water rate 12 sec2.510.315.5-3.8-3.73.9-3.03.93.4-3.13.0-1.51.5
Patch foraging water rate 18 sec1.22.86.8-2.2-2.12.4-1.72.61.2-1.00.7-0.1-0.1
Patch foraging water rate 24 sec2.84.06.8-2.6-2.62.6-2.02.51.7-1.71.6-0.90.7
Patch foraging water rate 6 sec3.45.09.7-2.9-2.72.6-2.03.12.2-2.11.9-0.70.6
Seeking ratio, delayed vs. immediate footshock0.10.20.3-0.5-0.50.5-0.40.60.3-0.3-0.1-0.2-0.2
Distance traveled before self-admin0.30.72.01.00.9-1.00.6-1.4-0.90.8-0.60.00.1
Distance traveled after self-admin0.30.61.40.60.5-0.40.6-0.90.5-0.61.1-0.71.2
Extensor digitorum longus weight5.923.434.95.85.9-5.85.5-5.0-4.74.2-3.73.5-3.2
Bone: elastic displacement0.91.22.3-1.0-1.01.0-0.51.41.4-1.31.5-0.20.5
Bone: elastic work0.70.92.11.11.0-1.01.5-0.2-0.60.6-0.31.3-1.1
Bone: endosteal estimation1.02.56.0-1.2-1.31.3-1.91.3-1.51.9-2.41.0-1.8
Bone: endosteal perimeter0.92.35.3-1.4-1.41.5-2.31.1-1.21.6-2.20.4-1.3
Epididymis fat weight1.26.214.6-3.5-3.53.2-3.82.51.2-0.90.2-1.70.7
Delta time in closed arm before/after self-admin0.70.72.50.40.3-0.10.60.8-0.70.8-0.71.6-1.1
Delta time in open arm before/after self-admin0.50.62.40.50.4-0.90.4-1.50.1-0.30.4-1.11.0
Diff in mean of infusions in LGA sessions0.20.41.00.80.8-0.71.0-0.8-0.50.3-0.10.3-0.3
Delay discount exponential model param0.30.41.2-0.1-0.0-0.0-0.2-0.20.8-0.80.7-1.01.1
Extinction: sum of active levers before priming1.42.23.51.71.6-1.91.6-1.7-1.61.4-1.31.0-0.5
Active lever presses in extinction session 62.62.66.12.02.0-2.31.7-2.5-1.41.1-1.00.30.1
Bone: final force2.33.74.82.22.2-2.01.7-1.9-2.22.0-2.11.3-1.4
Bone: final moment2.13.54.52.12.1-1.91.7-1.9-2.12.0-2.01.3-1.4
Food consumed during 24 hour testing period0.30.71.70.20.2-0.20.1-0.70.9-1.01.2-1.11.3
Glucose1.62.65.5-2.2-2.12.0-2.32.3-0.20.5-0.90.6-0.7
Heart weight1.62.64.2-1.3-1.21.0-1.02.0-1.41.8-1.92.0-2.0
Delay discount hyperbolic model param0.40.51.3-0.1-0.0-0.0-0.2-0.20.9-0.90.9-1.01.1
Intermittent access intake day 1-15 change0.31.94.0-1.4-1.41.1-1.40.31.4-1.41.2-2.01.6
Intermittent access intake escalation0.31.74.1-1.2-1.21.0-1.30.11.4-1.31.1-2.01.7
Intermittent access intake escalation 21.01.63.7-1.1-1.11.1-1.30.11.3-1.31.1-1.91.7
Intermitt. access day 1 inactive lever presses0.00.40.6-0.3-0.40.4-0.40.10.8-0.70.7-0.80.8
Intermitt. access day 15 inactive lever presses0.42.04.5-1.6-1.62.0-2.10.81.1-1.00.5-1.51.2
Intermitt. access escalation Index0.82.64.1-2.0-2.01.8-1.72.01.6-1.41.4-0.80.6
Intermittent access day 1 total infusions0.92.67.1-1.9-1.92.0-2.71.7-0.50.8-1.50.2-1.0
Intermittent access day 15 total infusions1.84.411.9-2.8-2.82.7-3.41.71.1-0.80.1-1.80.9
Intermittent access terminal intake (last 3 days)1.93.310.6-2.6-2.52.3-3.31.40.3-0.0-0.6-1.30.3
Intermittent access total infusions2.42.88.8-2.3-2.22.2-3.01.6-0.10.4-1.1-0.6-0.3
Intermittent access day 1 locomotion0.91.74.7-1.7-1.71.8-2.21.5-0.20.5-0.9-0.0-0.6
Intermittent access day 15 total locomotion0.93.49.4-2.5-2.52.4-3.11.20.8-0.70.0-1.90.9
Intermittent access total locomotion3.94.714.3-3.0-3.02.9-3.81.70.6-0.3-0.5-1.60.4
Intermittent access standard deviation0.31.52.6-1.4-1.41.6-1.60.91.0-0.90.8-1.21.1
Left kidney weight0.21.33.2-1.5-1.71.4-1.81.3-0.10.3-0.7-0.1-0.5
Right kidney weight0.10.71.9-1.1-1.21.1-1.40.90.1-0.0-0.5-0.4-0.1
Cocaine induced anxiety0.00.10.40.20.2-0.10.0-0.6-0.0-0.10.0-0.40.5
Post-drug Anxiety0.40.40.90.90.9-0.70.6-0.9-0.60.6-0.30.2-0.1
Baseline Anxiety0.20.30.80.60.6-0.60.80.0-0.30.5-0.00.9-0.7
Tail length0.21.13.41.61.5-1.41.8-1.0-0.1-0.30.50.50.1
Length with tail1.35.810.13.23.1-3.03.2-2.3-2.01.6-1.32.0-1.3
Length without tail0.94.87.52.72.6-2.72.7-1.9-2.11.8-1.42.0-1.4
Times rat made contact with spout0.30.31.10.80.8-0.71.1-0.50.0-0.10.30.3-0.1
Lifetime Intake1.82.26.4-1.9-1.91.9-2.51.6-0.30.6-1.2-0.1-0.6
Liver weight, left0.50.92.4-1.2-1.31.1-1.11.50.00.2-0.40.4-0.7
Liver weight, right1.42.57.2-2.0-2.12.0-1.72.70.10.3-0.41.0-1.0
Locomotor activity1.42.25.0-1.9-2.01.8-1.32.21.3-1.11.1-0.30.4
Locomotor testing distance1.02.67.2-2.2-2.21.9-1.42.71.1-1.01.00.10.1
Locomotor testing rearing0.62.26.1-2.0-2.01.9-1.42.51.0-0.80.90.10.1
Locomotion in novel chamber3.14.28.5-2.8-2.62.6-2.92.11.5-1.20.8-1.50.9
Locomotion in novel chamber post-restriction1.13.25.7-2.2-2.22.1-2.41.61.6-1.51.0-1.51.1
Fecal boli incidents, locomotor time 10.10.20.90.20.2-0.4-0.1-1.0-0.20.0-0.1-0.80.7
Change in fecal boli incidents, locomotor task0.60.61.8-0.3-0.10.6-0.11.1-0.40.5-0.81.2-1.3
Time >=10cm from walls, locomotor time 10.50.72.0-0.6-0.70.9-1.40.1-0.60.7-1.4-0.4-0.2
Bouts of movement, locomotor time 11.72.23.71.21.3-1.11.6-1.91.0-1.31.7-1.61.9
Total resting periods, locomotor time 11.72.04.10.91.1-0.91.2-1.71.1-1.31.6-1.72.0
Rest time, locomotor task time 11.01.72.2-1.5-1.41.1-1.40.91.4-1.51.0-1.51.0
Distance moved, locomotor task time 10.30.82.00.50.3-0.40.3-0.1-1.21.4-0.91.2-1.3
Vertical activity count, locomotor time 10.10.71.5-1.0-1.21.2-1.11.2-0.00.3-0.20.3-0.5
Time >=10cm from walls, locomotor time 20.20.51.30.40.40.0-0.0-1.00.4-0.60.5-1.21.1
Bouts of movement, locomotor time 20.10.40.80.60.7-0.90.8-0.90.2-0.30.4-0.40.5
Total resting periods, locomotor time 20.00.20.40.30.4-0.60.4-0.60.2-0.30.4-0.40.5
Rest time, locomotor task time 21.01.73.8-1.8-1.81.6-1.91.80.5-0.4-0.2-0.5-0.1
Distance moved, locomotor task time 20.70.92.01.41.3-1.21.4-1.3-0.30.20.30.20.2
Vertical activity count, locomotor time 20.10.10.50.0-0.10.20.30.30.5-0.60.70.00.3
Light reinforcement 10.10.30.7-0.1-0.30.3-0.10.10.8-0.80.8-0.70.7
Light reinforcement 20.61.32.7-0.8-0.91.4-1.60.21.0-0.90.4-1.71.3
Bone: marrow area1.12.75.9-1.3-1.31.4-1.91.4-1.41.8-2.41.0-1.8
Bone: maximum diameter0.20.41.10.60.6-0.5-0.0-1.1-0.90.8-0.9-0.1-0.2
Bone: maximum force3.36.511.52.52.6-2.31.7-2.4-3.23.0-3.41.7-2.1
Bone: maximum moment3.15.910.22.42.4-2.21.6-2.2-3.02.9-3.21.7-2.0
Mean time between licks in bursts0.10.41.40.50.5-0.51.00.3-0.30.3-0.11.2-0.8
Mean num. licks in bursts0.10.20.4-0.5-0.50.4-0.20.60.6-0.50.4-0.10.1
Cd content in liver0.91.02.0-1.2-1.21.0-1.30.30.9-0.90.5-1.40.7
Co content in liver1.72.04.8-1.3-1.21.0-0.41.42.0-1.92.2-0.80.9
Cu content in liver0.10.20.5-0.1-0.10.0-0.0-0.00.6-0.60.7-0.40.5
Fe content in liver0.30.41.00.30.3-0.50.3-0.3-0.90.9-1.00.7-0.7
K content in liver1.41.42.70.80.6-0.80.8-0.2-1.51.5-1.41.5-1.7
Mg content in liver0.40.41.1-0.5-0.60.5-0.41.0-0.30.5-0.50.8-1.0
Mn content in liver2.02.35.01.92.0-1.91.7-2.2-1.21.0-1.00.2-0.3
Na content in liver0.30.30.60.70.8-0.70.7-0.6-0.40.3-0.40.3-0.4
Rb content in liver1.31.64.4-1.7-1.71.6-1.52.10.6-0.3-0.00.2-0.6
Se content in liver0.30.41.1-0.4-0.40.3-0.6-0.40.5-0.50.4-1.00.9
Sr content in liver1.91.63.71.71.7-1.81.7-1.9-0.30.10.3-0.10.5
Zn content in liver0.30.30.80.80.7-0.90.9-0.70.1-0.10.60.20.3
Bone: minimum diameter0.81.53.0-1.1-1.11.2-1.71.1-1.01.2-1.70.6-1.2
Time in familiar zone, hab. session 10.20.20.5-0.6-0.60.5-0.50.5-0.20.1-0.60.0-0.7
Time in novel zone, hab. session 10.20.20.7-0.3-0.30.4-0.20.80.3-0.20.60.50.2
Total zone transitions, hab. session 10.30.50.91.01.0-0.70.7-0.8-0.60.5-0.40.4-0.4
Total locomotion distance, hab. session 10.40.60.9-0.6-0.60.9-0.90.8-0.40.7-0.90.4-0.9
Locomotion velocity, hab. session 10.10.20.6-0.1-0.10.3-0.40.3-0.40.6-0.70.3-0.7
Time in familiar zone, hab. session 20.20.20.7-0.1-0.1-0.10.60.5-0.20.10.00.8-0.7
Time in novel zone, hab. session 20.10.10.20.30.3-0.1-0.2-0.4-0.10.1-0.1-0.20.4
Total zone transitions, hab. session 21.82.43.91.41.4-1.11.0-0.7-1.92.0-1.91.7-1.8
Total locomotion distance, hab. session 20.91.23.30.00.00.2-0.30.6-1.31.5-1.71.3-1.8
Locomotion velocity, hab. session 20.81.12.8-0.2-0.20.4-0.60.7-1.21.4-1.71.1-1.7
Novel to familiar place preference ratio0.71.03.41.21.2-1.20.8-1.8-0.70.5-0.3-0.40.7
Novelty place preference0.40.52.10.80.8-0.80.4-1.4-0.30.2-0.0-0.60.9
Time in novel zone, NPP test0.30.41.50.70.6-0.70.4-1.2-0.40.3-0.1-0.40.7
Total zone transitions, NPP test1.92.84.02.02.0-1.71.6-1.6-1.91.8-1.51.4-1.2
Total locomotion distance, NPP test0.50.71.60.30.30.1-0.10.3-1.11.2-1.31.1-1.3
Locomotion velocity, NPP test0.30.41.00.40.30.0-0.00.1-0.80.9-1.00.7-0.9
Intraocular pressure2.23.67.6-1.3-1.20.9-1.0-0.12.2-2.42.3-2.72.8
Delta distance traveled before/after self-admin0.50.51.6-0.4-0.40.60.00.91.0-1.01.3-0.10.5
Delta ambulatory time before/after self-admin0.20.31.2-0.2-0.20.40.20.70.8-0.71.10.20.2
Parametrial fat weight1.84.210.2-3.0-3.02.7-3.22.40.8-0.5-0.1-0.80.2
Pavlov. Cond. lever latency0.30.40.6-0.6-0.60.7-0.60.50.8-0.80.7-0.50.6
Pavlov. Cond. magazine entry latency0.40.51.00.60.6-0.70.4-0.8-1.00.9-0.90.4-0.6
Pavlov. Cond. change in total contacts0.20.20.90.30.3-0.50.0-0.9-0.1-0.0-0.0-0.70.7
Pavlov. Cond. index score0.20.30.80.60.6-0.80.6-0.9-0.30.1-0.0-0.30.1
Pavlov. Cond. latency score0.10.20.40.50.4-0.60.4-0.6-0.50.4-0.30.0-0.2
Pavlov. Cond. lever contacts0.30.30.60.30.3-0.50.3-0.2-0.80.8-0.80.6-0.7
Pavlov. Cond. magazine entry number0.40.51.5-0.7-0.70.8-0.61.2-0.10.3-0.50.7-0.7
Pavlov. Cond. intertrial magazine entries1.51.83.3-0.9-0.90.8-0.70.21.8-1.81.7-1.81.8
Pavlov. Cond. lever-magazine prob. diff.0.30.41.20.80.8-1.00.7-1.1-0.50.3-0.2-0.1-0.0
Pavlov. Cond. response bias0.20.30.90.60.6-0.70.5-0.9-0.1-0.00.1-0.40.3
Pavlov. Cond. lever latency0.40.61.7-0.9-0.90.8-0.51.30.8-0.60.60.1-0.1
Pavlov. Cond. magazine entry latency2.73.96.82.52.5-2.52.3-2.6-1.81.5-1.20.8-0.5
Pavlov. Cond. change in total contacts0.61.65.51.61.6-1.51.0-2.3-0.80.6-0.5-0.50.5
Pavlov. Cond. index score1.52.45.82.02.0-1.91.5-2.4-1.41.2-1.10.2-0.1
Pavlov. Cond. latency score1.32.14.91.81.8-1.71.3-2.2-1.41.2-1.20.2-0.1
Pavlov. Cond. lever contacts0.40.61.90.90.9-0.90.6-1.4-0.70.6-0.6-0.20.2
Pavlov. Cond. magazine entry number4.55.812.2-3.2-3.23.2-2.83.51.9-1.51.3-0.60.2
Pavlov. Cond. intertrial magazine entries0.41.01.7-1.3-1.31.1-1.21.00.9-0.90.7-0.80.3
Pavlov. Cond. lever-magazine prob. diff.1.92.96.72.12.2-2.11.7-2.6-1.51.2-1.10.2-0.0
Pavlov. Cond. response bias1.52.14.71.81.8-1.81.5-2.2-1.41.1-1.00.3-0.1
Time in closed arm before self-admin0.20.30.7-0.6-0.50.5-0.8-0.10.3-0.2-0.2-0.80.6
Time in closed arm after self-admin0.30.41.2-0.7-0.61.0-0.71.10.3-0.0-0.20.2-0.2
Time in open arm before self-admin0.60.72.8-0.4-0.40.40.21.70.10.10.41.4-1.2
Time in open arm after self-admin0.10.20.50.30.3-0.70.7-0.3-0.0-0.10.50.2-0.2
Bone: periosteal estimation0.51.24.30.1-0.00.1-0.7-0.1-1.51.6-2.10.7-1.4
Bone: periosteal perimeter0.40.82.40.50.4-0.2-0.2-0.5-1.31.3-1.50.6-1.0
Bone: post-yield work2.23.713.20.70.8-0.5-0.5-1.0-2.82.9-3.61.1-2.0
Progressive ratio test 1 active lever presses0.10.21.0-0.6-0.60.5-1.00.3-0.10.2-0.4-0.2-0.1
Progressive ratio test 1 breakpoint0.10.20.9-0.5-0.60.5-0.90.2-0.20.3-0.4-0.3-0.0
Progressive ratio test 1 inactive lever presses0.00.10.3-0.3-0.30.3-0.3-0.10.2-0.00.3-0.60.5
Progressive ratio test 2 active lever presses1.42.05.3-1.8-1.91.6-2.30.90.8-0.80.1-1.50.8
Progressive ratio test 2 breakpoint1.52.05.3-1.8-1.81.6-2.30.90.9-0.80.1-1.50.8
Progressive ratio test 2 inactive lever presses2.37.214.0-3.4-3.33.4-3.72.02.1-1.91.3-2.71.8
Incentive Sensitization - Responses0.10.20.7-0.2-0.2-0.1-0.5-0.3-0.50.4-0.8-0.3-0.2
Incentive Sensitization - Breakpoint0.10.20.6-0.5-0.40.1-0.8-0.1-0.30.2-0.7-0.4-0.1
Sum of active levers in priming session hrs 5-62.22.15.31.11.0-1.00.8-2.30.7-1.01.0-2.02.2
Progressive ratio0.82.24.31.21.3-1.40.7-1.1-2.01.9-2.11.3-1.4
Food seeking constrained by brief footshock0.10.10.40.10.1-0.20.30.2-0.30.3-0.20.7-0.2
Seeking ratio, punishment vs. effort0.91.93.3-1.5-1.61.5-0.71.81.7-1.51.7-0.40.7
Retroperitoneal fat weight5.323.846.4-6.8-6.76.6-6.56.33.1-2.41.2-2.00.8
Reaction time number correct0.10.20.50.60.6-0.60.7-0.6-0.0-0.00.2-0.00.2
Reaction time mean minus median0.63.68.02.32.5-2.21.8-2.8-1.71.4-1.70.2-0.5
Reaction time mean minus median AUC0.31.84.31.61.8-1.71.5-2.1-1.00.8-0.9-0.1-0.2
Reaction time num false alarms0.30.52.4-0.9-0.70.8-0.21.50.5-0.40.40.6-0.5
Reaction time num false alarms AUC0.10.20.8-0.2-0.10.00.50.90.1-0.00.10.8-0.5
Reaction time trials correct on left0.10.20.50.60.6-0.60.7-0.6-0.0-0.00.2-0.00.2
Reaction time trials on left0.10.30.70.70.8-0.70.8-0.7-0.10.00.2-0.00.2
Reaction time mean0.10.10.60.10.4-0.2-0.1-0.7-0.00.0-0.1-0.60.4
Reaction time mean AUC0.10.10.50.00.3-0.1-0.2-0.7-0.00.1-0.1-0.70.4
Median of all reaction times0.10.20.4-0.5-0.20.4-0.6-0.00.3-0.20.3-0.70.4
Reaction time omissions0.81.33.31.61.8-1.31.3-1.6-0.70.7-0.40.00.0
Reaction time false alarm rate0.30.41.8-0.8-0.70.6-0.21.40.1-0.0-0.10.7-0.7
Reaction time premature initiation rate1.92.95.21.92.0-2.02.3-0.8-1.41.3-0.92.1-1.5
Reaction time premature initiations1.23.58.22.42.5-2.52.9-1.5-1.21.0-0.51.7-1.0
Std. dev. reaction times0.30.92.91.21.4-1.10.9-1.7-0.50.4-0.7-0.50.2
Reaction time trials completed0.10.30.70.70.8-0.70.8-0.7-0.10.00.2-0.00.2
Reaction time trials AUC0.00.10.40.50.5-0.50.6-0.4-0.10.10.10.10.0
Run reversals in cocaine runway, females1.71.95.30.60.4-0.20.50.6-1.51.7-1.72.1-2.3
Run reversals in cocaine runway, males0.20.20.5-0.6-0.70.2-0.30.50.2-0.20.4-0.1-0.4
Latency to leave start box in cocaine runway0.20.31.1-0.1-0.40.4-0.70.4-0.40.6-1.10.3-0.4
Latency to leave start box in cocaine runway, F0.00.00.20.1-0.2-0.0-0.20.0-0.10.2-0.5-0.00.1
Latency to leave start box in cocaine runway, M0.50.41.4-0.1-0.00.3-0.40.3-0.70.8-1.20.7-0.9
Std. dev. time between licks in bursts0.10.20.9-0.2-0.20.30.31.00.10.10.20.9-0.6
Total sessions with >9 infusions0.50.71.9-0.2-0.20.2-0.60.3-1.01.1-1.40.7-1.3
Short access day 1 total inactive lever presses1.22.35.2-2.0-2.02.3-2.12.10.9-0.60.3-0.5-0.0
Short access day 10 total inactive lever presses0.10.71.2-0.8-0.81.0-0.61.11.0-0.90.7-0.30.6
Short access day 1 total infusions0.81.53.5-1.6-1.51.7-1.91.6-0.10.3-0.80.1-0.8
Short access day 10 total infusions0.91.63.8-0.8-0.80.8-1.50.8-1.31.4-2.00.8-1.6
Short access total infusions1.11.63.2-0.9-0.80.9-1.41.2-1.21.5-1.81.1-1.6
Short access day 1 locomotion0.71.12.6-1.5-1.51.5-1.61.20.30.0-0.3-0.4-0.1
Short access day 10 total locomotion0.20.72.2-1.2-1.21.2-1.50.70.10.2-0.3-0.40.1
Short access total locomotion0.71.13.3-1.4-1.51.5-1.81.10.10.2-0.5-0.4-0.1
One hour access (0.3 mA shock)4.14.810.0-3.0-3.02.9-3.22.31.4-1.20.7-1.51.0
Compulsive drug intake1.01.55.11.61.6-1.62.2-0.6-0.10.00.41.1-0.3
One hour access (shock baseline)2.36.114.1-3.3-3.33.2-3.82.01.6-1.30.7-2.21.4
Social response proportion0.40.61.21.01.0-1.00.8-1.1-0.60.5-0.30.1-0.2
Social responses0.20.30.90.60.6-0.90.9-0.7-0.40.10.1-0.0-0.1
Social time0.20.30.70.70.8-0.70.8-0.5-0.40.3-0.10.3-0.2
Soleus weight2.88.214.3-3.7-3.73.8-3.53.62.5-2.11.4-1.50.7
Bone: stiffness2.13.86.32.12.2-1.91.4-2.3-2.32.1-2.50.8-1.4
Tibialis anterior weight6.823.541.36.36.3-6.46.0-6.0-4.03.3-2.52.4-2.0
Time to tail flick, vehicle, before self-admin0.60.82.00.50.5-0.60.1-0.5-1.21.3-1.40.9-0.9
Time to tail flick, vehicle, after self-admin1.73.46.80.80.8-1.21.0-0.4-2.62.6-2.42.3-2.4
Time to tail flick, test, before self-admin1.51.73.7-1.5-1.51.5-1.51.9-0.40.6-1.00.7-1.4
Time to tail flick, test, after self-admin0.10.10.50.20.3-0.40.2-0.7-0.50.4-0.1-0.20.3
Delta time to tail flick, vehicle, before/after SA1.01.02.00.60.6-0.80.9-0.2-1.41.4-1.01.3-1.3
Delta time to tail flick, test, before/after SA2.02.55.11.51.5-1.51.5-2.20.7-1.01.6-1.42.2
Tibia length0.82.17.81.81.7-1.81.1-2.8-0.60.2-0.4-1.00.9
Ambulatory time before self-admin0.20.52.10.70.7-0.90.4-1.5-0.70.6-0.5-0.40.4
Ambulatory time after self-admin0.40.62.0-0.4-0.40.5-0.5-0.10.8-0.91.1-0.91.4
Bone: tissue strength0.00.10.2-0.1-0.00.1-0.2-0.10.2-0.3-0.0-0.50.4
Total heroin consumption3.44.07.82.72.7-2.62.7-2.8-1.41.1-0.60.60.1
Bone: trabecular number0.71.32.61.01.1-1.10.6-1.3-1.61.5-1.40.7-0.6
Bone: trabecular spacing0.40.61.3-0.9-0.80.8-0.31.11.0-1.00.6-0.2-0.0
Bone: trabecular thickness0.20.30.9-0.7-0.70.8-1.00.60.00.1-0.1-0.10.1
Bone: trabecular tissue density2.74.76.7-2.5-2.62.4-2.42.02.2-2.11.7-1.91.5
Water consumed over 24 hours0.50.92.31.31.3-1.21.5-1.20.1-0.30.7-0.00.4
Number of responses in last shaping day0.00.00.1-0.1-0.10.10.20.30.2-0.20.20.00.1