Hub : Traits

One hour access (0.3 mA shock)

Tags: Behavior · Cocaine

Project: p50_paul_meyer_2020

5 loci · 5 genes with independent associations · 5 total associated genes

Significant Loci

#	Chr	Start pos	End pos	# assoc genes	# joint models	Best TWAS P	Best GWAS P	Cond GWAS P	Joint genes
1	chr1	88613126	89913275	1	1	1.64e-08	1.05e-01	1.25e-01	Zfp575
2	chr4	176059677	177381574	1	1	1.80e-07	1.10e-01	1.44e-05	Slco1a1
3	chr8	41432021	42517271	1	1	1.04e-17	1.43e-01	2.10e-05	Foxred1
4	chr9	83390749	84777604	1	1	0.00e+00	2.09e-01	1.00e+00	Retreg2
5	chr17	61510864	62906219	1	1	4.88e-14	4.33e-02	3.83e-02	Ccny

Pleiotropic Associations

Trait	Chi2 ratio	# genes+	# genes++	% genes++	Corr	Corr P	Genes
BMI with tail	1281.74	3	1	20	0	1.00e+00	Foxred1 Retreg2 Slco1a1
BMI without tail	72013.97	2	2	40	0	1.00e+00	Ccny Retreg2
Body weight	3.43	2	0	0	0	1.00e+00	Retreg2 Slco1a1
Epididymis fat weight	54253.01	2	2	40	0	1.00e+00	Ccny Retreg2
Glucose	2366.35	1	1	20	0	1.00e+00	Retreg2
Heart weight	6763.89	2	2	40	0	1.00e+00	Ccny Retreg2
Left kidney weight	47087.73	3	1	20	0	1.00e+00	Ccny Foxred1 Retreg2
Right kidney weight	38954.96	3	2	40	0	1.00e+00	Ccny Foxred1 Retreg2
Tail length	46066.56	2	2	40	0	1.00e+00	Ccny Retreg2
Length with tail	3070.34	2	1	20	0	1.00e+00	Foxred1 Retreg2
Length without tail	32334.37	4	2	40	-0.99	6.40e-03	Ccny Retreg2 Slco1a1 Zfp575
Liver weight, left	7265.45	2	2	40	0	1.00e+00	Ccny Retreg2
Liver weight, right	129.69	2	1	20	0	1.00e+00	Ccny Retreg2
Parametrial fat weight	209.08	3	1	20	0	1.00e+00	Ccny Foxred1 Retreg2
Retroperitoneal fat weight	16055.76	1	1	20	0	1.00e+00	Retreg2
Intraocular pressure	40071.91	1	1	20	0	1.00e+00	Retreg2
Extensor digitorum longus weight	4682.69	1	1	20	0	1.00e+00	Retreg2
Soleus weight	40.27	3	1	20	0	1.00e+00	Ccny Retreg2 Slco1a1
Tibialis anterior weight	4881.94	1	1	20	0	1.00e+00	Retreg2
Tibia length	3259.43	1	1	20	0	1.00e+00	Retreg2
Number of licking bursts	78561.42	2	1	20	0	1.00e+00	Ccny Retreg2
Food consumed during 24 hour testing period	53104.21	2	1	20	0	1.00e+00	Ccny Retreg2
Times rat made contact with spout	305.36	1	1	20	0	1.00e+00	Retreg2
Mean time between licks in bursts	99755.05	2	1	20	0	1.00e+00	Ccny Retreg2
Mean num. licks in bursts	71302.54	2	1	20	0	1.00e+00	Ccny Retreg2
Std. dev. time between licks in bursts	94042.02	1	1	20	0	1.00e+00	Retreg2
Water consumed over 24 hours	51711.02	2	1	20	0	1.00e+00	Ccny Retreg2
Patch foraging indifference point 0 sec	115003.89	1	1	20	0	1.00e+00	Retreg2
Patch foraging indifference point AUC	66593.63	2	2	40	0	1.00e+00	Ccny Retreg2
Indifference point function ln k	71038.09	2	2	40	0	1.00e+00	Ccny Retreg2
Indifference point function log k	71038.09	2	2	40	0	1.00e+00	Ccny Retreg2
Patch foraging total patch changes 0 sec	60133.23	2	1	20	0	1.00e+00	Foxred1 Retreg2
Patch foraging total patch changes 12 sec	3670.27	3	2	40	0	1.00e+00	Ccny Foxred1 Retreg2
Patch foraging total patch changes 18 sec	58887.78	2	1	20	0	1.00e+00	Ccny Retreg2
Patch foraging total patch changes 24 sec	83555.1	2	2	40	0	1.00e+00	Ccny Retreg2
Patch foraging total patch changes 6 sec	16352.42	2	2	40	0	1.00e+00	Ccny Retreg2
Patch foraging time to switch 0 sec	156618.53	1	1	20	0	1.00e+00	Retreg2
Patch foraging water rate 0 sec	148807.58	1	1	20	0	1.00e+00	Retreg2
Patch foraging water rate 12 sec	80953.12	2	2	40	0	1.00e+00	Ccny Retreg2
Patch foraging water rate 18 sec	51643.12	2	1	20	0	1.00e+00	Ccny Retreg2
Patch foraging water rate 24 sec	2357.13	2	2	40	0	1.00e+00	Ccny Retreg2
Patch foraging water rate 6 sec	1353.95	3	2	40	0	1.00e+00	Ccny Retreg2 Zfp575
Locomotor activity	26.33	3	1	20	0	1.00e+00	Ccny Foxred1 Retreg2
Locomotor testing distance	22391.77	4	2	40	-1	4.96e-03	Ccny Foxred1 Retreg2 Slco1a1
Locomotor testing rearing	76209.02	2	1	20	0	1.00e+00	Foxred1 Retreg2
Light reinforcement 1	77669.42	2	2	40	0	1.00e+00	Ccny Retreg2
Light reinforcement 2	54020.7	2	2	40	0	1.00e+00	Ccny Retreg2
Reaction time number correct	76747.74	2	2	40	0	1.00e+00	Ccny Retreg2
Reaction time mean minus median	102906.71	2	1	20	0	1.00e+00	Ccny Retreg2
Reaction time mean minus median AUC	208396.98	1	1	20	0	1.00e+00	Retreg2
Reaction time num false alarms	28557.11	2	2	40	0	1.00e+00	Ccny Retreg2
Reaction time num false alarms AUC	53265.52	2	2	40	0	1.00e+00	Ccny Retreg2
Reaction time trials correct on left	76747.74	2	2	40	0	1.00e+00	Ccny Retreg2
Reaction time trials on left	75015.72	2	2	40	0	1.00e+00	Ccny Retreg2
Reaction time mean	47192.43	2	1	20	0	1.00e+00	Ccny Retreg2
Reaction time mean AUC	56674.13	2	1	20	0	1.00e+00	Ccny Retreg2
Median of all reaction times	31417.12	1	1	20	0	1.00e+00	Retreg2
Reaction time omissions	34267.91	1	1	20	0	1.00e+00	Retreg2
Reaction time false alarm rate	891.26	1	1	20	0	1.00e+00	Retreg2
Reaction time premature initiation rate	18442.81	2	1	20	0	1.00e+00	Ccny Retreg2
Reaction time premature initiations	69362.16	2	1	20	0	1.00e+00	Ccny Retreg2
Std. dev. reaction times	149487.71	1	1	20	0	1.00e+00	Retreg2
Reaction time trials completed	75015.72	2	2	40	0	1.00e+00	Ccny Retreg2
Reaction time trials AUC	75869.15	2	2	40	0	1.00e+00	Ccny Retreg2
Social response proportion	35302.65	1	1	20	0	1.00e+00	Retreg2
Social responses	2856.43	2	2	40	0	1.00e+00	Ccny Retreg2
Social time	22121.54	2	1	20	0	1.00e+00	Ccny Retreg2
Conditioned locomotion	3044.63	2	1	20	0	1.00e+00	Ccny Retreg2
Cocaine response after cond. corrected	32913.12	2	1	20	0	1.00e+00	Ccny Retreg2
Cocaine response after cond. not corrected	32126.2	2	1	20	0	1.00e+00	Ccny Retreg2
Cocaine response before conditioning	1409.02	2	1	20	0	1.00e+00	Ccny Retreg2
Saline control response	12962.78	1	1	20	0	1.00e+00	Retreg2
Condit. Reinf. active minus inactive responses	53410.48	1	1	20	0	1.00e+00	Retreg2
Condit. Reinf. active-inactive response ratio	91582.24	1	1	20	0	1.00e+00	Retreg2
Condit. Reinf. active responses	9691.24	1	1	20	0	1.00e+00	Retreg2
Condit. Reinf. inactive responses	21056.03	2	1	20	0	1.00e+00	Ccny Retreg2
Condit. Reinf. lever presses	15873.43	1	1	20	0	1.00e+00	Retreg2
Condit. Reinf. lever reinforcers received	2000.77	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. lever latency	10912.53	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry latency	24714.14	2	1	20	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. change in total contacts	114781.94	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. index score	23998.4	2	1	20	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. latency score	29242.48	2	1	20	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. lever contacts	22069.78	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry number	16773.11	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. intertrial magazine entries	104933.78	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. lever-magazine prob. diff.	22438.69	2	1	20	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. response bias	5169.79	1	1	20	0	1.00e+00	Retreg2
Conditioned reinforcement - actives	95753.16	2	2	40	0	1.00e+00	Ccny Retreg2
Conditioned reinforcement - inactives	51686.28	3	2	40	0	1.00e+00	Ccny Foxred1 Retreg2
Conditioned locomotion	13824.85	3	2	40	0	1.00e+00	Ccny Foxred1 Retreg2
Intermittent access intake day 1-15 change	70209.02	3	3	60	0	1.00e+00	Ccny Foxred1 Retreg2
Intermittent access intake escalation	104787.33	2	2	40	0	1.00e+00	Foxred1 Retreg2
Intermittent access intake escalation 2	36059.12	3	3	60	0	1.00e+00	Ccny Foxred1 Retreg2
Intermitt. access day 1 inactive lever presses	118272.07	2	1	20	0	1.00e+00	Ccny Retreg2
Intermitt. access day 15 inactive lever presses	104128.18	2	2	40	0	1.00e+00	Foxred1 Retreg2
Intermitt. access escalation Index	92502.05	2	1	20	0	1.00e+00	Ccny Retreg2
Intermittent access day 1 total infusions	38884.3	4	1	20	-0.99	8.50e-03	Ccny Foxred1 Retreg2 Slco1a1
Intermittent access day 15 total infusions	32884.11	4	2	40	0.99	7.56e-03	Ccny Foxred1 Retreg2 Zfp575
Intermittent access terminal intake (last 3 days)	20812.82	4	2	40	0.99	6.95e-03	Ccny Foxred1 Retreg2 Zfp575
Intermittent access total infusions	179.48	4	1	20	-0.93	7.28e-02	Ccny Foxred1 Retreg2 Zfp575
Intermittent access day 1 locomotion	26127.03	4	2	40	-0.99	5.83e-03	Ccny Foxred1 Retreg2 Slco1a1
Intermittent access day 15 total locomotion	88947.95	2	2	40	0	1.00e+00	Ccny Retreg2
Intermittent access total locomotion	359.59	2	1	20	0	1.00e+00	Retreg2 Zfp575
Intermittent access standard deviation	50490.97	4	2	40	0.99	5.85e-03	Ccny Foxred1 Retreg2 Slco1a1
Cocaine induced anxiety	40077.34	4	2	40	-0.99	1.11e-02	Ccny Foxred1 Retreg2 Zfp575
Post-drug Anxiety	10235.68	2	1	20	0	1.00e+00	Retreg2 Zfp575
Baseline Anxiety	34515.07	3	2	40	0	1.00e+00	Ccny Foxred1 Retreg2
Lifetime Intake	1724.95	4	2	40	-0.97	2.79e-02	Ccny Foxred1 Retreg2 Zfp575
Incentive Sensitization - Responses	54535.28	3	3	60	0	1.00e+00	Ccny Retreg2 Zfp575
Incentive Sensitization - Breakpoint	35706.63	4	3	60	-0.99	1.12e-02	Ccny Foxred1 Retreg2 Zfp575
Progressive ratio test 1 active lever presses	33314.65	3	2	40	0	1.00e+00	Ccny Retreg2 Slco1a1
Progressive ratio test 1 breakpoint	32105.26	3	2	40	0	1.00e+00	Ccny Retreg2 Slco1a1
Progressive ratio test 1 inactive lever presses	37783.15	4	3	60	0.99	6.21e-03	Ccny Foxred1 Retreg2 Slco1a1
Progressive ratio test 2 active lever presses	19092.31	3	2	40	0	1.00e+00	Ccny Retreg2 Zfp575
Progressive ratio test 2 breakpoint	11684.3	3	2	40	0	1.00e+00	Ccny Retreg2 Zfp575
Progressive ratio test 2 inactive lever presses	41032.59	4	2	40	0.99	6.28e-03	Ccny Foxred1 Retreg2 Slco1a1
Total sessions with >9 infusions	2016.76	4	2	40	-0.98	2.34e-02	Ccny Retreg2 Slco1a1 Zfp575
Short access day 1 total inactive lever presses	28607.93	4	3	60	-0.99	7.93e-03	Ccny Foxred1 Retreg2 Zfp575
Short access day 10 total inactive lever presses	108624.06	2	2	40	0	1.00e+00	Ccny Retreg2
Short access day 1 total infusions	22348.8	5	2	40	-0.98	2.60e-03	Ccny Foxred1 Retreg2 Slco1a1 Zfp575
Short access day 10 total infusions	38150.26	2	1	20	0	1.00e+00	Ccny Retreg2
Short access total infusions	17026.24	2	2	40	0	1.00e+00	Ccny Retreg2
Short access day 1 locomotion	16829.38	5	3	60	0.99	8.88e-04	Ccny Foxred1 Retreg2 Slco1a1 Zfp575
Short access day 10 total locomotion	60541.98	3	3	60	0	1.00e+00	Ccny Foxred1 Retreg2
Short access total locomotion	22766.65	3	2	40	0	1.00e+00	Foxred1 Retreg2 Slco1a1
Compulsive drug intake	16369.62	4	2	40	-0.99	1.14e-02	Ccny Foxred1 Retreg2 Zfp575
One hour access (shock baseline)	28058.45	5	1	20	0.99	1.08e-03	Ccny Foxred1 Retreg2 Slco1a1 Zfp575
Number of responses in last shaping day	10288.03	5	2	40	0.99	1.75e-03	Ccny Foxred1 Retreg2 Slco1a1 Zfp575
Context. condit. distance diff. score	488.1	2	1	20	0	1.00e+00	Ccny Retreg2
Locomotion velocity, session 1	14615.25	1	1	20	0	1.00e+00	Retreg2
Locomotion distance, session 1	2213.01	2	1	20	0	1.00e+00	Ccny Retreg2
Locomotion velocity, session 2	9358	1	1	20	0	1.00e+00	Retreg2
Locomotion distance, session 2	1206.44	2	1	20	0	1.00e+00	Ccny Retreg2
Locomotion velocity, session 3	2332.53	1	1	20	0	1.00e+00	Retreg2
Locomotion distance, session 3	16615.78	1	1	20	0	1.00e+00	Retreg2
Stereotopy head waving bouts, day 3	5866.4	1	1	20	0	1.00e+00	Retreg2
Stereotopy head waving duration, day 3	12131.92	1	1	20	0	1.00e+00	Retreg2
Locomotion velocity, session 7	1310.17	1	1	20	0	1.00e+00	Retreg2
Locomotion distance, session 7	3744.54	1	1	20	0	1.00e+00	Retreg2
Stereotopy head waving bouts, day 7	10466.92	1	1	20	0	1.00e+00	Retreg2
Stereotopy head waving duration, day 7	8847.36	1	1	20	0	1.00e+00	Retreg2
Locomotion velocity, session 8	950.4	2	1	20	0	1.00e+00	Ccny Retreg2
Locomotion distance, session 8	673.32	1	1	20	0	1.00e+00	Retreg2
Degree of sensitization distance	15309.16	1	1	20	0	1.00e+00	Retreg2
Degree of sensitization stereotypy	8496.38	1	1	20	0	1.00e+00	Retreg2
Condit. Reinf. active minus inactive responses	2066.34	2	1	20	0	1.00e+00	Ccny Retreg2
Condit. Reinf. active-inactive response ratio	1097.66	1	1	20	0	1.00e+00	Retreg2
Condit. Reinf. active responses	5839.15	2	1	20	0	1.00e+00	Ccny Retreg2
Condit. Reinf. inactive responses	19375.3	1	1	20	0	1.00e+00	Retreg2
Incentive salience index mean	7397.37	2	1	20	0	1.00e+00	Ccny Retreg2
Condit. Reinf. lever presses	21433.81	1	1	20	0	1.00e+00	Retreg2
Time in familiar zone, hab. session 1	41873.03	1	1	20	0	1.00e+00	Retreg2
Time in novel zone, hab. session 1	35522.88	1	1	20	0	1.00e+00	Retreg2
Total zone transitions, hab. session 1	1818.53	1	1	20	0	1.00e+00	Retreg2
Total locomotion distance, hab. session 1	849.35	2	1	20	0	1.00e+00	Ccny Retreg2
Locomotion velocity, hab. session 1	571.33	2	1	20	0	1.00e+00	Ccny Retreg2
Time in familiar zone, hab. session 2	23379.25	1	1	20	0	1.00e+00	Retreg2
Time in novel zone, hab. session 2	24924.95	1	1	20	0	1.00e+00	Retreg2
Total zone transitions, hab. session 2	280.53	1	1	20	0	1.00e+00	Retreg2
Total locomotion distance, hab. session 2	51.92	2	1	20	0	1.00e+00	Ccny Retreg2
Locomotion velocity, hab. session 2	77.91	2	1	20	0	1.00e+00	Ccny Retreg2
Novel to familiar place preference ratio	27759.88	2	1	20	0	1.00e+00	Ccny Retreg2
Novelty place preference	27195.73	2	1	20	0	1.00e+00	Ccny Retreg2
Time in novel zone, NPP test	40844.77	1	1	20	0	1.00e+00	Retreg2
Total zone transitions, NPP test	8230.03	1	1	20	0	1.00e+00	Retreg2
Total locomotion distance, NPP test	3566.83	2	2	40	0	1.00e+00	Ccny Retreg2
Locomotion velocity, NPP test	2031.76	2	2	40	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. lever latency	2195.61	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry latency	8.04	1	0	0	0	1.00e+00	Ccny
Pavlov. Cond. change in total contacts	2273.55	2	1	20	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. index score	1769.33	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. latency score	1841.19	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. lever contacts	3029.77	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry number	1086.53	2	1	20	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. intertrial magazine entries	524.02	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. lever-magazine prob. diff.	1940.27	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. response bias	2606.99	1	1	20	0	1.00e+00	Retreg2
Bone: apparent density	22268.03	1	1	20	0	1.00e+00	Retreg2
Bone surface	25125.6	1	1	20	0	1.00e+00	Retreg2
Bone volume	33831.7	1	1	20	0	1.00e+00	Retreg2
Bone: connectivity density	7098.55	1	1	20	0	1.00e+00	Retreg2
Bone: cortical apparent density	22635.68	2	1	20	0	1.00e+00	Ccny Retreg2
Bone: cortical area	18930.98	1	1	20	0	1.00e+00	Retreg2
Bone: cortical porosity	1837.29	1	1	20	0	1.00e+00	Retreg2
Bone: cortical porosity	4807.78	1	1	20	0	1.00e+00	Retreg2
Bone: cortical thickness	1627.26	1	1	20	0	1.00e+00	Retreg2
Bone: cortical thickness	12190.6	1	1	20	0	1.00e+00	Retreg2
Bone: cortical tissue density	24229.43	2	1	20	0	1.00e+00	Ccny Retreg2
Bone: elastic displacement	29626.25	1	1	20	0	1.00e+00	Retreg2
Bone: elastic work	1494.59	1	1	20	0	1.00e+00	Retreg2
Bone: endosteal estimation	35257.61	1	1	20	0	1.00e+00	Retreg2
Bone: endosteal perimeter	44697.39	1	1	20	0	1.00e+00	Retreg2
Bone: final force	7031.22	1	1	20	0	1.00e+00	Retreg2
Bone: final moment	1042.62	1	1	20	0	1.00e+00	Retreg2
Bone: marrow area	37067.95	1	1	20	0	1.00e+00	Retreg2
Bone: maximum diameter	24401.62	1	1	20	0	1.00e+00	Retreg2
Bone: maximum force	34553.99	1	1	20	0	1.00e+00	Retreg2
Bone: maximum moment	24715.64	1	1	20	0	1.00e+00	Retreg2
Bone: minimum diameter	17196.64	1	1	20	0	1.00e+00	Retreg2
Bone: periosteal estimation	38190.5	1	1	20	0	1.00e+00	Retreg2
Bone: periosteal perimeter	43183.28	1	1	20	0	1.00e+00	Retreg2
Bone: post-yield work	50847.58	1	1	20	0	1.00e+00	Retreg2
Bone: stiffness	35564.91	1	1	20	0	1.00e+00	Retreg2
Bone: tissue strength	12264.67	1	1	20	0	1.00e+00	Retreg2
Bone: trabecular number	41138.39	1	1	20	0	1.00e+00	Retreg2
Bone: trabecular spacing	31287.85	1	1	20	0	1.00e+00	Retreg2
Bone: trabecular thickness	33264.33	1	1	20	0	1.00e+00	Retreg2
Bone: trabecular tissue density	26819.29	2	2	40	0	1.00e+00	Ccny Retreg2
Breakpoint value in progressive ratio session	56221.29	2	1	20	0	1.00e+00	Ccny Retreg2
Distance traveled before self-admin	33523.09	4	2	40	0.99	1.24e-02	Ccny Foxred1 Retreg2 Zfp575
Distance traveled after self-admin	25239.07	4	2	40	0.99	1.41e-02	Ccny Foxred1 Retreg2 Zfp575
Delta time in closed arm before/after self-admin	696.27	3	2	40	0	1.00e+00	Ccny Foxred1 Retreg2
Delta time in open arm before/after self-admin	27441.91	2	2	40	0	1.00e+00	Ccny Retreg2
Diff in mean of infusions in LGA sessions	108490.77	1	1	20	0	1.00e+00	Retreg2
Extinction: sum of active levers before priming	30592.19	3	3	60	0	1.00e+00	Ccny Foxred1 Retreg2
Active lever presses in extinction session 6	1120.26	3	2	40	0	1.00e+00	Ccny Foxred1 Retreg2
Delta distance traveled before/after self-admin	4197.63	3	2	40	0	1.00e+00	Ccny Foxred1 Retreg2
Delta ambulatory time before/after self-admin	32038.95	3	2	40	0	1.00e+00	Ccny Foxred1 Retreg2
Time in closed arm before self-admin	22074.06	4	2	40	-0.99	1.07e-02	Ccny Foxred1 Retreg2 Slco1a1
Time in closed arm after self-admin	9901.19	2	2	40	0	1.00e+00	Ccny Retreg2
Time in open arm before self-admin	11582.65	3	2	40	0	1.00e+00	Ccny Retreg2 Zfp575
Time in open arm after self-admin	657.22	3	2	40	0	1.00e+00	Ccny Foxred1 Retreg2
Sum of active levers in priming session hrs 5-6	3877.89	1	1	20	0	1.00e+00	Retreg2
Time to tail flick, vehicle, before self-admin	12970.42	4	2	40	0.98	2.08e-02	Ccny Foxred1 Retreg2 Slco1a1
Time to tail flick, vehicle, after self-admin	29582.1	4	2	40	0.99	6.92e-03	Ccny Foxred1 Retreg2 Zfp575
Time to tail flick, test, before self-admin	8209.19	4	1	20	-0.99	8.87e-03	Ccny Foxred1 Retreg2 Zfp575
Time to tail flick, test, after self-admin	1999.21	3	2	40	0	1.00e+00	Ccny Foxred1 Retreg2
Delta time to tail flick, vehicle, before/after SA	12304.47	3	2	40	0	1.00e+00	Ccny Retreg2 Slco1a1
Delta time to tail flick, test, before/after SA	28423.85	2	1	20	0	1.00e+00	Ccny Retreg2
Ambulatory time before self-admin	57052.95	3	3	60	0	1.00e+00	Ccny Foxred1 Retreg2
Ambulatory time after self-admin	44153.3	2	2	40	0	1.00e+00	Ccny Retreg2
Total heroin consumption	373.08	3	3	60	0	1.00e+00	Ccny Foxred1 Retreg2
Area under the delay curve	40810.48	2	1	20	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 0s delay	4741.82	2	1	20	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 16s delay	37437.33	2	2	40	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 2s delay	416.46	2	1	20	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 24s delay	50025	2	2	40	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 4s delay	1298.29	2	2	40	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 8s delay	101423.99	1	1	20	0	1.00e+00	Retreg2
Delay discount exponential model param	30110.07	2	1	20	0	1.00e+00	Ccny Retreg2
Delay discount hyperbolic model param	45715.54	1	1	20	0	1.00e+00	Retreg2
Fecal boli incidents, locomotor time 1	75084.64	2	1	20	0	1.00e+00	Ccny Retreg2
Change in fecal boli incidents, locomotor task	11821.21	2	2	40	0	1.00e+00	Ccny Retreg2
Time >=10cm from walls, locomotor time 1	16439.48	3	2	40	0	1.00e+00	Ccny Retreg2 Slco1a1
Bouts of movement, locomotor time 1	20842.46	2	2	40	0	1.00e+00	Ccny Retreg2
Total resting periods, locomotor time 1	5936.78	2	2	40	0	1.00e+00	Ccny Retreg2
Rest time, locomotor task time 1	37983.55	2	1	20	0	1.00e+00	Ccny Retreg2
Distance moved, locomotor task time 1	79651.82	2	2	40	0	1.00e+00	Ccny Retreg2
Vertical activity count, locomotor time 1	109532.09	2	1	20	0	1.00e+00	Retreg2 Zfp575
Time >=10cm from walls, locomotor time 2	80995.71	2	1	20	0	1.00e+00	Ccny Retreg2
Bouts of movement, locomotor time 2	58110.85	3	2	40	0	1.00e+00	Ccny Foxred1 Retreg2
Total resting periods, locomotor time 2	63368.4	3	2	40	0	1.00e+00	Ccny Foxred1 Retreg2
Rest time, locomotor task time 2	41900.71	2	2	40	0	1.00e+00	Ccny Retreg2
Distance moved, locomotor task time 2	17217.33	2	2	40	0	1.00e+00	Ccny Retreg2
Vertical activity count, locomotor time 2	69238.05	2	2	40	0	1.00e+00	Ccny Retreg2
Weight adjusted by age	54019.35	3	2	40	0	1.00e+00	Ccny Retreg2 Zfp575
Seeking ratio, delayed vs. immediate footshock	16476.57	3	2	40	0	1.00e+00	Ccny Retreg2 Zfp575
Locomotion in novel chamber	8161.06	2	2	40	0	1.00e+00	Ccny Retreg2
Locomotion in novel chamber post-restriction	77324.49	2	1	20	0	1.00e+00	Ccny Retreg2
Progressive ratio	78975.01	2	2	40	0	1.00e+00	Ccny Retreg2
Food seeking constrained by brief footshock	3674.99	2	1	20	0	1.00e+00	Retreg2 Zfp575
Seeking ratio, punishment vs. effort	59148.59	2	2	40	0	1.00e+00	Ccny Retreg2
Run reversals in cocaine runway, females	12403.43	3	1	20	0	1.00e+00	Ccny Foxred1 Retreg2
Run reversals in cocaine runway, males	9965.89	3	1	20	0	1.00e+00	Ccny Foxred1 Retreg2
Latency to leave start box in cocaine runway	29317.55	2	2	40	0	1.00e+00	Ccny Retreg2
Latency to leave start box in cocaine runway, F	28379.24	1	1	20	0	1.00e+00	Retreg2
Latency to leave start box in cocaine runway, M	1842.99	4	2	40	-0.97	2.52e-02	Ccny Foxred1 Retreg2 Zfp575
Co content in liver	4721.74	1	1	20	0	1.00e+00	Retreg2
Cu content in liver	162.43	1	1	20	0	1.00e+00	Retreg2
Fe content in liver	5656.2	1	1	20	0	1.00e+00	Retreg2
K content in liver	6593.53	1	1	20	0	1.00e+00	Retreg2
Mg content in liver	24493.99	1	1	20	0	1.00e+00	Retreg2
Mn content in liver	4374.36	1	1	20	0	1.00e+00	Retreg2
Na content in liver	16641.94	1	1	20	0	1.00e+00	Retreg2
Rb content in liver	428.45	1	1	20	0	1.00e+00	Retreg2
Zn content in liver	15755.62	1	1	20	0	1.00e+00	Retreg2

Associations by panel

Tissue	RNA modality	# hits	% hits/tests	Avg chisq
Adipose	alternative polyA	0	0	1.09
Adipose	alternative TSS	0	0	1.1
Adipose	gene expression	0	0	1.14
Adipose	isoform ratio	0	0	1.08
Adipose	intron excision ratio	0	0	1.04
Adipose	mRNA stability	0	0	1.14
BLA	alternative polyA	0	0	1.18
BLA	alternative TSS	0	0	1.09
BLA	gene expression	0	0	1.16
BLA	isoform ratio	0	0	1.14
BLA	intron excision ratio	0	0	1.16
BLA	mRNA stability	0	0	1.16
Brain	alternative polyA	0	0	1.11
Brain	alternative TSS	0	0	1.12
Brain	gene expression	0	0	1.12
Brain	isoform ratio	0	0	1.14
Brain	intron excision ratio	0	0	1.1
Brain	mRNA stability	0	0	1.15
Eye	alternative polyA	0	0	1.2
Eye	alternative TSS	0	0	1.17
Eye	gene expression	0	0	1.15
Eye	isoform ratio	0	0	1.21
Eye	intron excision ratio	0	0	1.21
Eye	mRNA stability	0	0	1.17
IC	alternative polyA	0	0	1.17
IC	alternative TSS	0	0	1.05
IC	gene expression	0	0	1.18
IC	isoform ratio	0	0	1.17
IC	intron excision ratio	0	0	1.17
IC	mRNA stability	0	0	1.17
IL	alternative polyA	0	0	1.16
IL	alternative TSS	0	0	1.16
IL	gene expression	0	0	1.13
IL	isoform ratio	0	0	1.24
IL	intron excision ratio	0	0	1.17
IL	mRNA stability	0	0	1.2
LHb	alternative polyA	0	0	1.12
LHb	alternative TSS	0	0	1.27
LHb	gene expression	0	0	1.17
LHb	isoform ratio	0	0	1.25
LHb	intron excision ratio	0	0	1.14
LHb	mRNA stability	0	0	1.18
Liver	alternative polyA	0	0	1.11
Liver	alternative TSS	0	0	1.13
Liver	gene expression	0	0	1.15
Liver	isoform ratio	0	0	1.16
Liver	intron excision ratio	0	0	1.13
Liver	mRNA stability	1	0	1.17
NAcc	alternative polyA	1	0	4.33
NAcc	alternative TSS	0	0	1.11
NAcc	gene expression	0	0	1.15
NAcc	isoform ratio	0	0	1.16
NAcc	intron excision ratio	1	0	1.15
NAcc	mRNA stability	0	0	1.18
OFC	alternative polyA	0	0	1.17
OFC	alternative TSS	0	0	1.14
OFC	gene expression	0	0	1.13
OFC	isoform ratio	0	0	1.17
OFC	intron excision ratio	0	0	1.18
OFC	mRNA stability	0	0	1.21
PL	alternative polyA	0	0	1.19
PL	alternative TSS	0	0	1.09
PL	gene expression	0	0	1.14
PL	isoform ratio	0	0	1.16
PL	intron excision ratio	0	0	1.14
PL	mRNA stability	1	0	1.19
pVTA	alternative polyA	0	0	1.14
pVTA	alternative TSS	0	0	1.18
pVTA	gene expression	1	0	1.17
pVTA	isoform ratio	0	0	1.18
pVTA	intron excision ratio	0	0	1.2
pVTA	mRNA stability	0	0	1.19
RMTg	alternative polyA	0	0	1.07
RMTg	alternative TSS	0	0	1.03
RMTg	gene expression	0	0	1.2
RMTg	isoform ratio	0	0	1.23
RMTg	intron excision ratio	0	0	1.16
RMTg	mRNA stability	0	0	1.26