Hub : Genes

Cbr1l2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression Cbr1l2 0.15 0.07 6.8e-14 0.16 0.17 0.18 0.17 1.4e-12 1.6e-13 4.6e-14 4.7e-14
2 Brain intron excision ratio chr11_46346786_46347257 0.06 0.03 1.2e-06 0.06 0.07 0.07 0.07 4.8e-06 4.7e-07 4.6e-07 3.7e-07
3 Liver gene expression Cbr1l2 0.22 0.09 0.0e+00 0.21 0.23 0.22 0.22 1.3e-22 5.7e-25 2.1e-24 2.8e-24
4 RMTg gene expression Cbr1l2 0.27 0.14 2.0e-06 0.26 0.24 0.25 0.25 2.0e-07 5.7e-07 3.0e-07 3.0e-07
5 BLA intron excision ratio chr11_46346786_46347257 0.05 0.04 6.5e-03 0.05 0.02 0.04 0.04 1.1e-03 3.3e-02 5.7e-03 4.1e-03
6 NAcc intron excision ratio chr11_46379646_46380552 0.09 0.04 1.0e-13 0.09 0.08 0.08 0.08 4.7e-13 1.6e-12 4.2e-12 1.1e-12
7 pVTA intron excision ratio chr11_46363568_46364473 0.23 0.09 0.0e+00 0.16 0.24 0.22 0.22 3.8e-13 5.4e-19 5.0e-18 1.6e-17
8 pVTA intron excision ratio chr11_46347364_46348270 0.07 0.05 7.2e-04 0.04 0.02 0.03 0.04 1.4e-04 6.2e-03 3.1e-03 2.0e-04
9 PL intron excision ratio chr11_46363568_46364473 0.04 0.03 4.8e-05 0.04 0.05 0.04 0.05 6.6e-05 8.6e-06 1.3e-05 5.1e-06
10 PL intron excision ratio chr11_46379646_46380552 0.03 0.02 1.6e-03 0.02 0.02 0.01 0.02 1.2e-03 2.9e-03 2.8e-02 3.5e-03
11 IC intron excision ratio chr11_46362976_46363461 0.1 0.07 9.9e-03 0.03 0.03 0 0.02 2.9e-02 2.0e-02 2.8e-01 5.6e-02
12 BLA intron excision ratio chr11_46363568_46364473 0.05 0.03 5.5e-03 0.04 0.03 0.01 0.03 4.3e-03 1.1e-02 8.3e-02 1.0e-02
13 Brain intron excision ratio chr11_46347364_46348270 0.06 0.04 8.9e-06 0.05 0.04 0.04 0.04 2.9e-05 4.8e-05 5.7e-05 2.9e-04
14 NAcc gene expression Cbr1l2 0.15 0.07 0.0e+00 0.13 0.11 0.12 0.06 3.1e-19 1.2e-16 9.0e-18 2.4e-09
15 pVTA intron excision ratio chr11_46379646_46380552 0.09 0.04 3.0e-05 0.05 0.06 0.05 0.05 1.3e-04 2.1e-05 3.8e-05 7.4e-05
16 LHb intron excision ratio chr11_46379646_46380552 0.17 0.11 9.7e-03 0.01 0.04 -0 0.01 2.3e-01 3.9e-02 3.7e-01 1.5e-01
17 Brain intron excision ratio chr11_46363568_46364473 0.15 0.07 1.3e-15 0.13 0.16 0.17 0.15 6.7e-12 4.5e-15 9.9e-16 4.6e-14
18 NAcc intron excision ratio chr11_46363568_46364473 0.17 0.07 0.0e+00 0.19 0.19 0.22 0.2 6.2e-28 3.0e-28 3.1e-33 2.5e-30
19 Adipose gene expression Cbr1l2 0.94 0.01 0.0e+00 0.51 0.59 0.61 0.61 1.0e-64 4.7e-81 7.8e-86 9.0e-86
20 Eye intron excision ratio chr11_46379646_46380552 0.46 0.16 4.8e-03 0.03 0.06 0.06 0.07 1.1e-01 5.2e-02 3.9e-02 3.1e-02
21 Brain intron excision ratio chr11_46379646_46380552 0.08 0.04 1.2e-04 0.03 0.04 0.03 0.03 6.9e-04 2.0e-04 2.1e-03 1.2e-03
22 Adipose mRNA stability Cbr1l2 0.17 0.08 2.8e-15 0.08 0.11 0.11 0.1 6.5e-09 1.5e-12 5.6e-12 2.1e-11
23 Brain mRNA stability Cbr1l2 0.03 0.02 6.3e-03 0.03 0.02 0.05 0.03 7.9e-04 2.6e-03 3.2e-05 5.9e-04
24 NAcc mRNA stability Cbr1l2 0.07 0.04 4.3e-06 0.04 0.03 0.03 0.04 1.3e-06 1.9e-05 2.8e-05 4.5e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density0.10.10.50.00.4-0.40.30.2-0.40.7-0.30.5-0.50.10.40.00.0-0.70.10.50.5-0.0-0.2-0.3-0.2-0.4-0.5
Area under the delay curve0.30.41.8-0.20.2-0.40.40.30.50.30.50.20.3-0.8-0.2-0.70.60.50.80.7-0.10.10.71.11.01.01.3
BMI with tail0.41.42.81.41.3-1.61.51.3-1.41.7-1.21.4-1.50.91.1-1.01.1-1.31.41.41.20.51.1-0.00.9-0.4-0.1
BMI without tail0.00.10.40.10.3-0.30.20.3-0.10.6-0.10.0-0.5-0.2-0.20.1-0.0-0.50.20.40.4-0.30.40.00.1-0.1-0.2
Body weight0.10.41.40.60.2-0.60.30.60.10.20.20.0-0.3-0.20.1-0.10.30.11.10.4-0.0-0.51.21.21.2-1.00.5
Weight adjusted by age0.60.82.1-0.9-0.90.8-0.4-0.41.4-1.11.4-1.01.1-1.3-1.10.7-0.81.3-0.1-0.5-1.0-0.70.31.40.5-0.40.9
Bone surface4.27.612.03.43.5-3.33.23.4-3.03.0-3.13.4-3.12.83.1-3.03.2-2.22.72.82.42.61.9-0.81.81.10.3
Bone volume2.34.06.32.32.5-2.42.42.4-2.22.3-2.22.5-2.32.02.2-2.12.3-1.72.02.21.91.81.4-0.61.20.70.0
Breakpoint value in progressive ratio session0.30.31.80.40.6-0.3-0.01.1-0.40.0-0.50.80.20.40.0-0.60.70.20.40.10.40.90.60.00.41.30.5
Number of licking bursts0.30.51.2-1.1-0.90.7-0.6-0.90.6-0.30.6-0.70.4-0.8-0.40.9-1.0-0.0-0.8-0.3-0.3-0.9-0.8-0.1-0.7-0.8-0.4
Context. condit. distance diff. score0.70.93.10.90.2-0.40.80.70.5-0.40.40.10.0-0.20.2-0.60.91.11.30.3-0.50.31.81.61.71.61.7
Locomotion velocity, session 10.10.10.70.10.0-0.0-0.2-0.1-0.20.1-0.10.1-0.30.40.40.1-0.1-0.4-0.30.10.40.2-0.6-0.5-0.40.9-0.6
Locomotion distance, session 10.81.05.71.40.9-0.90.90.8-0.90.4-0.71.0-1.01.00.9-1.21.2-0.20.90.70.61.20.7-0.10.72.40.7
Locomotion velocity, session 20.20.20.70.40.4-0.40.70.5-0.20.0-0.30.30.10.30.1-0.40.50.30.70.30.00.50.80.60.80.10.4
Locomotion distance, session 20.20.20.90.10.2-0.30.40.40.10.10.00.20.1-0.30.0-0.50.40.40.70.50.10.50.70.80.90.90.8
Locomotion velocity, session 32.83.27.52.42.2-1.81.72.0-2.11.5-2.41.9-2.02.72.4-1.72.0-1.71.01.41.52.00.4-1.60.31.4-0.6
Locomotion distance, session 30.91.02.21.10.9-1.00.50.7-1.01.2-1.20.9-1.31.21.5-0.60.8-1.40.30.91.10.7-0.3-1.1-0.21.4-0.7
Stereotopy head waving bouts, day 31.92.310.4-0.40.20.4-0.7-0.7-1.10.4-1.10.0-0.71.50.81.0-1.0-2.1-2.0-0.41.0-0.1-2.5-3.1-2.8-1.1-3.2
Stereotopy head waving duration, day 31.11.36.1-0.10.20.2-0.4-0.5-1.00.4-1.00.2-0.71.30.60.7-0.6-1.7-1.4-0.21.00.1-1.9-2.4-2.1-0.9-2.5
Locomotion velocity, session 70.80.91.7-1.1-1.31.1-1.1-1.01.2-1.11.3-1.20.7-1.0-1.11.1-1.10.9-0.8-0.9-0.9-0.9-0.70.5-0.40.30.1
Locomotion distance, session 70.81.02.5-0.9-1.20.8-0.8-0.61.3-1.01.5-0.90.8-1.6-1.30.8-0.71.3-0.0-0.5-1.1-0.80.31.50.60.70.9
Stereotopy head waving bouts, day 71.01.14.11.41.2-0.90.90.8-1.20.7-1.50.9-1.22.01.4-0.60.8-1.20.20.31.00.90.0-1.4-0.3-0.5-1.0
Stereotopy head waving duration, day 71.01.23.71.91.5-1.21.31.3-1.00.5-1.31.0-1.21.91.3-1.11.2-0.61.00.40.71.10.9-0.60.6-0.10.0
Locomotion velocity, session 82.42.96.02.42.0-1.91.81.8-1.81.4-1.91.8-2.22.52.3-1.51.7-1.51.41.41.51.70.7-0.80.81.4-0.4
Locomotion distance, session 80.81.24.10.90.2-0.70.90.90.3-0.10.10.3-0.1-0.20.3-0.91.11.11.60.6-0.30.61.91.82.01.92.0
Degree of sensitization distance1.51.63.4-1.3-1.41.2-0.8-0.81.4-1.51.8-1.21.4-1.7-1.71.0-1.01.7-0.3-1.0-1.6-0.90.41.60.4-0.91.0
Degree of sensitization stereotypy1.81.94.72.21.7-1.61.71.6-1.21.0-1.61.4-1.41.91.6-1.61.7-0.81.50.91.01.31.4-0.31.10.00.3
Conditioned locomotion0.80.92.0-1.2-1.11.2-0.9-0.71.0-1.20.9-1.11.4-1.0-1.20.9-1.01.1-0.8-1.0-1.1-0.6-0.30.5-0.4-0.20.0
Cocaine response after cond. corrected0.10.20.60.30.00.2-0.1-0.20.4-0.80.4-0.20.30.1-0.40.10.10.80.1-0.4-0.60.10.30.50.40.50.7
Cocaine response after cond. not corrected0.20.31.20.2-0.10.3-0.00.00.6-0.90.6-0.40.4-0.1-0.40.10.11.00.2-0.5-0.9-0.00.50.70.50.71.1
Cocaine response before conditioning0.20.20.80.30.2-0.20.40.80.10.10.10.2-0.1-0.2-0.0-0.50.40.30.50.3-0.20.20.80.50.60.70.9
Saline control response1.11.53.41.81.6-1.11.51.4-1.50.8-1.41.4-1.01.40.8-1.51.4-0.60.90.80.71.60.9-0.60.61.80.3
Bone: connectivity density0.91.42.61.21.5-1.51.21.2-1.41.6-1.31.5-1.61.11.6-1.21.2-1.31.01.41.30.90.5-0.50.50.1-0.1
Bone: cortical apparent density0.00.00.50.0-0.10.00.10.1-0.0-0.10.10.00.1-0.1-0.30.0-0.10.10.1-0.00.10.10.20.20.10.70.2
Bone: cortical area0.30.51.51.10.7-0.50.91.1-0.2-0.2-0.40.4-0.10.60.5-0.50.80.50.90.2-0.20.51.20.61.00.40.7
Bone: cortical porosity0.50.51.3-0.9-0.80.8-0.6-0.60.9-0.70.8-0.80.9-1.2-1.00.6-0.70.8-0.5-0.5-0.7-0.7-0.20.5-0.20.00.2
Bone: cortical porosity0.40.51.1-0.8-0.70.8-0.6-0.50.9-0.70.8-0.80.9-1.1-0.90.5-0.60.8-0.5-0.6-0.8-0.6-0.20.5-0.1-0.10.3
Bone: cortical thickness1.42.35.4-1.2-1.51.7-1.2-1.02.1-2.31.9-1.92.0-1.4-1.61.6-1.32.2-0.7-1.7-1.9-1.20.21.50.2-0.11.0
Bone: cortical thickness0.40.50.9-0.8-0.80.9-0.9-0.60.9-0.90.7-0.90.9-0.8-0.60.6-0.70.8-0.6-0.6-0.6-0.6-0.20.4-0.30.10.3
Bone: cortical tissue density0.00.00.50.0-0.0-0.00.00.1-0.10.00.00.10.0-0.1-0.20.0-0.1-0.00.00.00.10.10.10.10.00.70.1
Condit. Reinf. active minus inactive responses0.10.10.2-0.4-0.10.3-0.3-0.50.2-0.2-0.2-0.20.3-0.2-0.20.1-0.00.2-0.4-0.2-0.00.0-0.5-0.2-0.3-0.1-0.0
Condit. Reinf. active-inactive response ratio0.30.30.7-0.7-0.60.7-0.5-0.70.5-0.70.4-0.60.7-0.4-0.50.5-0.50.5-0.6-0.6-0.5-0.3-0.40.0-0.4-0.8-0.0
Condit. Reinf. active responses0.00.10.40.10.20.1-0.2-0.20.1-0.1-0.30.00.2-0.10.2-0.30.40.30.00.10.00.3-0.2-0.00.10.60.4
Condit. Reinf. inactive responses0.10.11.10.50.3-0.2-0.10.1-0.40.2-0.50.3-0.30.40.6-0.40.4-0.2-0.00.10.20.2-0.3-0.4-0.11.10.1
Incentive salience index mean0.10.10.6-0.6-0.50.4-0.4-0.80.5-0.40.1-0.40.6-0.5-0.30.2-0.10.5-0.2-0.2-0.2-0.1-0.20.30.0-0.10.3
Condit. Reinf. lever presses0.30.41.1-0.6-0.80.5-0.4-0.90.8-0.80.6-0.60.9-0.8-0.50.2-0.11.10.0-0.4-0.6-0.10.20.90.5-0.10.8
Condit. Reinf. active minus inactive responses1.41.84.51.51.1-1.31.61.7-0.70.6-0.61.2-0.60.70.8-1.61.70.31.81.20.41.51.91.01.92.11.5
Condit. Reinf. active-inactive response ratio0.50.61.60.40.4-0.70.90.9-0.10.4-0.10.6-0.0-0.20.2-0.90.90.41.10.90.10.71.11.01.31.31.1
Condit. Reinf. active responses1.21.73.71.91.5-1.31.71.8-1.20.7-1.21.4-1.11.51.2-1.61.6-0.41.41.00.71.61.4-0.01.11.60.6
Condit. Reinf. inactive responses0.81.03.11.81.3-1.01.31.4-1.20.5-1.21.1-1.11.71.1-1.01.0-0.70.70.40.51.00.8-0.70.30.2-0.3
Condit. Reinf. lever presses0.81.12.21.51.0-1.21.41.3-1.10.7-1.01.2-1.01.20.8-1.21.2-0.41.20.80.81.31.10.11.01.10.2
Condit. Reinf. lever reinforcers received1.52.14.42.11.6-1.51.91.9-1.30.9-1.31.6-1.21.61.3-1.71.8-0.41.61.20.81.71.60.11.41.70.7
Conditioned reinforcement - actives0.81.43.7-1.1-1.51.0-0.8-0.71.9-1.31.3-1.21.1-1.6-1.31.1-0.51.6-0.0-0.8-1.3-1.20.41.60.70.21.4
Conditioned reinforcement - inactives3.24.78.6-2.4-2.72.7-2.9-2.62.5-2.92.4-2.62.3-1.8-2.12.2-1.92.3-2.1-2.4-2.3-1.7-1.70.5-1.2-0.50.5
Conditioned locomotion0.30.40.9-1.0-0.51.0-0.6-0.50.6-0.90.3-0.70.7-0.6-0.90.3-0.50.7-0.9-0.6-0.5-0.0-0.3-0.2-0.60.70.0
Patch foraging indifference point 0 sec0.91.74.3-1.0-1.71.5-0.9-1.41.7-2.11.7-1.71.2-0.7-0.91.5-1.61.4-0.8-1.6-1.7-1.2-0.20.9-0.3-1.60.1
Patch foraging indifference point AUC0.81.22.91.61.5-1.11.61.7-1.00.5-0.71.0-0.81.10.5-1.31.3-0.11.40.80.41.31.60.41.3-0.00.5
Delay disc. indifference point, 0s delay0.60.61.90.20.6-0.70.60.60.20.5-0.00.6-0.0-0.30.1-0.91.00.31.11.00.20.61.31.01.21.41.3
Delay disc. indifference point, 16s delay0.00.00.2-0.3-0.20.00.0-0.20.20.30.2-0.0-0.0-0.5-0.10.0-0.0-0.1-0.10.20.1-0.2-0.3-0.0-0.10.30.1
Delay disc. indifference point, 2s delay0.20.30.9-0.00.4-0.6-0.00.5-0.00.7-0.10.5-0.3-0.10.6-0.40.6-0.20.70.90.50.20.20.50.60.90.8
Delay disc. indifference point, 24s delay0.60.71.9-0.8-0.60.8-0.4-0.51.0-0.81.1-0.61.1-1.4-1.20.3-0.21.3-0.2-0.5-1.0-0.4-0.21.00.30.61.2
Delay disc. indifference point, 4s delay0.80.83.00.70.9-0.81.21.1-0.10.6-0.00.80.2-0.5-0.2-1.20.80.41.40.8-0.00.41.71.41.50.51.1
Delay disc. indifference point, 8s delay0.40.51.8-0.6-0.40.20.0-0.31.2-0.41.2-0.60.8-0.9-0.5-0.30.11.00.50.2-0.7-0.30.61.30.90.61.2
Indifference point function ln k0.81.52.9-1.6-1.41.5-1.6-1.41.5-1.31.3-1.41.7-1.6-1.20.8-1.01.4-1.2-1.1-1.1-0.8-0.80.5-0.60.20.6
Indifference point function log k0.81.52.9-1.6-1.41.5-1.6-1.41.5-1.31.3-1.41.7-1.6-1.20.8-1.01.4-1.2-1.1-1.1-0.8-0.80.5-0.60.20.6
Patch foraging total patch changes 0 sec0.61.23.3-0.8-1.31.2-0.6-1.11.4-1.81.4-1.41.0-0.5-0.71.2-1.21.3-0.6-1.4-1.6-1.0-0.00.8-0.1-1.40.2
Patch foraging total patch changes 12 sec0.30.31.31.00.7-0.40.90.8-0.8-0.1-0.60.6-0.61.10.3-0.60.4-0.20.40.10.20.90.5-0.30.3-0.2-0.3
Patch foraging total patch changes 18 sec0.20.31.11.00.6-0.41.00.8-0.5-0.2-0.20.4-0.50.90.5-0.50.50.20.60.1-0.20.60.90.20.60.10.2
Patch foraging total patch changes 24 sec0.50.92.71.40.9-0.81.31.2-0.30.0-0.20.6-0.70.60.3-1.21.10.51.40.60.11.01.60.81.50.71.1
Patch foraging total patch changes 6 sec0.10.21.20.7-0.10.10.20.0-0.2-0.7-0.2-0.2-0.61.10.40.4-0.1-0.0-0.2-0.6-0.30.1-0.1-0.6-0.3-0.4-0.4
Patch foraging time to switch 0 sec0.10.10.70.2-0.1-0.40.0-0.3-0.50.8-0.50.5-0.50.10.3-0.0-0.0-0.80.00.30.6-0.3-0.4-0.4-0.20.2-0.3
Patch foraging water rate 0 sec0.40.93.40.90.9-0.90.61.0-1.10.6-1.01.0-1.51.81.9-0.50.7-1.00.30.71.01.1-0.0-1.1-0.10.2-0.6
Patch foraging water rate 12 sec0.61.42.9-1.0-1.51.1-0.8-0.81.7-1.71.6-1.31.2-1.1-0.71.1-1.11.7-0.2-1.0-1.5-1.10.61.60.5-0.31.1
Patch foraging water rate 18 sec0.20.31.10.30.4-0.60.00.5-0.30.7-0.60.3-1.00.61.0-0.30.4-0.80.30.71.00.50.0-0.5-0.01.0-0.2
Patch foraging water rate 24 sec0.40.63.7-0.1-0.40.2-0.20.10.7-0.80.8-0.20.6-0.60.1-0.20.31.30.5-0.0-0.9-0.10.81.31.01.01.9
Patch foraging water rate 6 sec0.10.22.30.1-0.20.0-0.20.10.3-0.40.30.0-0.30.10.5-0.10.20.40.20.2-0.00.40.20.30.41.50.6
Seeking ratio, delayed vs. immediate footshock0.60.82.7-1.4-0.90.5-1.5-1.30.00.20.2-0.40.5-0.70.21.2-1.1-0.5-0.90.00.4-0.9-1.6-0.4-1.0-1.1-0.9
Distance traveled before self-admin0.10.21.00.30.3-0.1-0.20.3-0.7-0.1-0.40.1-0.40.5-0.5-0.20.3-0.1-0.0-0.20.40.80.2-0.5-0.11.0-0.1
Distance traveled after self-admin0.20.20.80.20.4-0.60.50.6-0.60.9-0.40.4-0.9-0.1-0.3-0.40.3-0.60.60.50.90.10.30.10.40.1-0.1
Extensor digitorum longus weight3.313.221.84.24.3-4.03.73.8-4.64.4-4.64.4-4.74.34.2-3.53.4-4.22.23.53.83.21.1-3.00.40.6-1.6
Bone: elastic displacement0.70.82.5-1.1-0.81.0-1.2-1.20.6-0.60.6-0.90.4-0.5-0.31.0-0.9-0.0-1.3-0.8-0.4-0.9-1.6-0.7-1.3-1.1-0.6
Bone: elastic work0.20.31.7-0.4-0.30.5-0.7-0.50.1-0.2-0.0-0.3-0.10.20.40.5-0.4-0.3-0.9-0.40.0-0.3-1.3-0.9-1.0-0.7-0.6
Bone: endosteal estimation3.27.010.63.03.1-3.23.02.9-3.13.2-3.23.3-2.82.63.0-3.03.1-2.42.42.92.52.41.5-1.01.40.6-0.3
Bone: endosteal perimeter2.14.47.62.82.5-2.52.72.7-2.11.9-2.22.5-1.82.02.0-2.52.7-1.02.52.01.32.02.20.12.00.80.7
Epididymis fat weight0.82.66.52.41.8-1.62.02.3-1.00.8-1.11.4-0.80.90.9-2.02.10.22.21.30.51.42.61.12.31.61.7
Delta time in closed arm before/after self-admin0.40.41.00.20.2-0.70.80.3-0.20.9-0.40.5-0.5-0.6-0.3-0.30.3-0.40.90.70.3-0.61.00.80.8-1.00.1
Delta time in open arm before/after self-admin0.50.52.90.50.4-0.5-0.50.2-0.70.5-0.40.5-1.71.21.0-0.30.4-1.0-0.10.31.00.6-0.6-1.2-0.50.8-0.4
Diff in mean of infusions in LGA sessions0.70.92.41.11.4-0.60.41.4-1.30.2-1.31.5-0.41.30.7-1.31.4-0.10.40.20.51.50.3-0.70.31.00.4
Delay discount exponential model param0.30.41.60.2-0.10.3-0.3-0.2-0.5-0.2-0.6-0.2-0.30.70.20.6-0.5-0.5-0.8-0.60.1-0.1-0.7-1.1-1.0-0.9-1.2
Extinction: sum of active levers before priming0.40.41.30.70.2-0.21.01.0-0.1-0.4-0.00.50.40.4-0.1-0.50.50.70.60.1-0.40.71.10.60.81.10.8
Active lever presses in extinction session 61.01.02.9-0.7-0.81.3-0.8-1.00.4-1.30.3-0.80.90.2-1.01.3-1.20.3-1.7-1.5-0.7-0.3-1.2-1.1-1.6-0.2-1.1
Bone: final force0.40.61.31.10.9-0.81.01.1-0.80.4-0.80.9-0.70.90.9-0.80.9-0.30.80.60.40.90.6-0.00.70.20.1
Bone: final moment0.40.61.41.20.9-0.81.11.1-0.80.4-0.80.9-0.70.90.9-0.80.9-0.20.80.60.40.90.70.00.70.30.2
Food consumed during 24 hour testing period0.40.61.1-0.7-0.90.8-0.5-0.70.9-1.11.0-0.90.8-0.6-1.00.9-0.90.9-0.4-0.9-0.9-0.6-0.10.7-0.0-0.20.3
Glucose4.16.512.23.53.2-2.93.23.1-2.92.6-3.02.9-2.93.12.7-2.72.7-2.32.02.32.22.41.4-1.41.01.6-0.3
Heart weight0.10.10.6-0.10.1-0.1-0.20.2-0.20.30.00.30.6-0.7-0.8-0.10.20.20.30.10.10.00.20.40.40.00.2
Delay discount hyperbolic model param0.40.41.80.1-0.30.4-0.4-0.4-0.4-0.3-0.5-0.3-0.30.70.10.7-0.6-0.5-0.9-0.70.1-0.1-0.8-1.2-1.1-0.9-1.3
Intermittent access intake day 1-15 change0.71.43.7-1.2-1.21.5-1.9-1.41.0-1.40.8-1.01.3-1.0-1.51.1-1.20.9-1.4-1.7-0.8-1.0-0.9-0.2-1.0-1.0-0.3
Intermittent access intake escalation0.61.33.6-1.2-1.11.5-1.9-1.41.0-1.30.8-0.91.2-1.0-1.51.0-1.30.7-1.4-1.6-0.6-1.0-1.0-0.2-1.1-1.1-0.4
Intermittent access intake escalation 20.30.31.1-0.3-0.30.8-0.9-0.40.4-0.80.2-0.30.9-0.3-0.80.2-0.30.7-0.8-1.0-0.5-0.0-0.1-0.3-0.5-0.20.1
Intermitt. access day 1 inactive lever presses0.83.06.3-2.2-1.92.1-1.6-1.42.1-2.12.3-2.02.5-2.1-2.11.6-1.92.0-1.3-1.6-1.9-1.3-0.41.2-0.5-0.80.5
Intermitt. access day 15 inactive lever presses0.61.33.7-0.9-0.91.5-1.7-1.00.8-1.91.0-1.01.9-0.8-1.80.6-0.61.7-1.1-1.5-1.30.1-0.50.2-0.40.70.5
Intermitt. access escalation Index0.30.41.5-1.0-0.50.7-0.6-0.61.1-0.70.7-0.71.2-0.8-0.30.4-0.60.7-0.5-0.2-0.5-0.3-0.20.5-0.2-0.10.1
Intermittent access day 1 total infusions0.81.32.8-1.1-1.71.2-1.0-1.71.7-1.51.4-1.30.6-1.0-0.71.3-0.61.4-0.6-0.9-1.4-1.1-0.70.8-0.00.01.2
Intermittent access day 15 total infusions2.63.88.4-2.1-2.42.5-2.9-2.72.2-2.61.9-2.11.6-1.6-2.01.9-1.91.8-2.1-2.4-1.7-1.6-1.80.1-1.3-0.70.3
Intermittent access terminal intake (last 3 days)2.43.26.5-1.8-2.12.3-2.6-2.42.2-2.42.0-1.91.5-1.6-2.01.4-1.51.9-1.7-2.1-1.7-1.3-1.40.4-0.9-0.30.8
Intermittent access total infusions2.32.85.5-1.7-2.22.0-2.2-2.32.1-2.21.9-1.81.1-1.4-1.51.8-1.41.6-1.5-1.9-1.6-1.6-1.40.4-0.8-0.50.6
Intermittent access day 1 locomotion1.72.25.1-1.7-2.11.6-1.2-1.72.1-1.92.3-1.71.0-1.7-1.41.3-1.31.7-0.7-1.2-1.7-1.4-0.41.30.0-0.41.1
Intermittent access day 15 total locomotion0.61.03.6-0.8-1.01.3-0.3-0.71.2-1.91.3-0.91.3-0.7-1.00.6-0.61.8-0.6-1.1-1.5-0.30.40.70.00.20.9
Intermittent access total locomotion2.73.37.9-1.8-2.22.2-1.6-1.62.4-2.82.5-1.91.8-1.8-2.11.4-1.52.6-1.2-2.0-2.3-1.2-0.41.3-0.2-0.21.2
Intermittent access standard deviation0.20.51.3-0.3-0.50.8-1.1-1.00.4-0.90.3-0.50.10.3-0.10.7-0.70.1-1.0-0.9-0.3-0.3-1.1-0.8-1.0-0.4-0.5
Left kidney weight1.67.515.5-2.8-3.22.6-2.7-2.33.6-2.93.5-2.73.2-3.9-3.42.3-1.93.5-0.8-2.3-3.0-2.90.03.30.7-1.32.5
Right kidney weight1.67.513.1-2.7-3.32.7-2.7-2.33.6-3.13.6-3.03.1-3.4-3.42.7-2.33.2-1.1-2.6-3.1-2.9-0.32.80.2-1.72.0
Cocaine induced anxiety0.10.10.5-0.4-0.20.5-0.2-0.40.3-0.70.2-0.50.30.00.10.4-0.20.6-0.4-0.2-0.30.0-0.30.1-0.20.30.3
Post-drug Anxiety0.80.92.80.91.0-0.61.31.3-0.3-0.1-0.40.40.10.30.2-1.01.10.81.20.7-0.01.11.71.01.41.31.2
Baseline Anxiety0.50.52.50.50.3-0.70.80.90.00.6-0.10.50.2-0.6-0.5-0.60.60.31.30.60.20.01.61.31.40.10.7
Tail length1.14.37.4-2.4-2.32.6-2.6-2.02.5-2.72.6-2.72.2-2.0-2.42.2-2.12.1-2.0-2.2-2.0-1.5-1.30.7-1.1-0.20.3
Length with tail0.31.22.6-0.8-1.11.0-1.2-0.51.6-1.51.6-1.41.1-1.3-1.20.8-0.81.6-0.1-0.9-1.2-0.90.31.50.5-0.41.0
Length without tail0.10.31.00.80.4-0.50.30.6-0.2-0.0-0.20.3-0.40.40.6-0.60.60.30.90.2-0.00.20.90.71.0-0.90.6
Times rat made contact with spout7.78.913.4-3.5-3.33.6-3.6-3.23.4-3.63.7-3.63.2-3.0-3.33.0-3.12.8-2.7-3.3-3.1-2.6-1.91.2-1.5-2.00.6
Lifetime Intake1.62.04.5-1.6-1.91.7-1.9-2.11.7-1.61.4-1.60.8-1.2-1.21.7-1.31.0-1.4-1.5-1.2-1.6-1.50.1-1.0-0.60.1
Liver weight, left4.57.512.3-3.5-3.23.1-2.9-2.83.3-2.93.1-3.33.4-3.4-3.23.0-2.72.6-2.2-2.5-2.7-2.8-1.41.6-1.1-1.60.6
Liver weight, right2.23.97.2-2.5-2.52.1-2.3-2.71.9-1.62.1-2.21.4-2.0-1.62.5-2.60.8-2.0-1.8-1.5-2.5-1.60.3-1.6-2.1-0.6
Locomotor activity1.82.86.2-1.4-1.41.5-1.0-1.02.5-1.92.5-1.82.0-2.3-2.11.1-1.42.3-0.2-1.2-2.1-1.40.82.40.7-0.51.5
Locomotor testing distance0.71.23.1-0.9-1.31.1-0.7-1.11.7-1.41.7-1.40.6-1.1-1.01.2-1.31.1-0.4-1.0-1.4-1.3-0.01.20.0-0.80.6
Locomotor testing rearing0.30.51.7-0.6-0.60.4-0.1-0.31.2-0.71.1-0.60.5-1.0-0.90.2-0.51.00.3-0.3-0.8-0.60.71.30.7-0.50.9
Locomotion in novel chamber0.10.10.4-0.1-0.30.4-0.6-0.40.1-0.60.4-0.10.3-0.2-0.20.1-0.10.5-0.3-0.4-0.40.1-0.00.1-0.10.50.1
Locomotion in novel chamber post-restriction0.20.41.70.00.5-0.30.20.4-0.70.8-0.70.3-0.80.50.5-0.10.1-1.1-0.50.40.80.1-0.7-1.3-0.90.1-0.9
Fecal boli incidents, locomotor time 10.60.83.80.00.0-0.30.30.50.2-0.10.50.20.6-0.9-0.8-0.50.91.21.20.4-0.50.51.61.71.61.31.9
Change in fecal boli incidents, locomotor task2.22.14.1-2.0-1.31.9-1.6-1.41.7-1.61.8-1.71.9-1.8-2.01.0-1.81.2-1.6-1.3-1.1-0.8-1.30.4-1.0-0.6-0.3
Time >=10cm from walls, locomotor time 10.50.61.9-0.7-0.70.9-0.5-0.51.0-1.00.8-0.91.4-0.6-1.10.3-0.90.9-0.6-0.9-1.0-0.4-0.00.4-0.2-0.7-0.3
Bouts of movement, locomotor time 10.10.10.40.00.3-0.20.20.2-0.20.2-0.30.60.20.40.1-0.20.3-0.20.00.30.30.60.0-0.3-0.10.2-0.4
Total resting periods, locomotor time 10.10.10.50.10.3-0.10.30.4-0.30.0-0.20.60.30.3-0.0-0.30.30.10.10.30.20.70.2-0.10.10.4-0.2
Rest time, locomotor task time 11.92.35.71.41.5-1.51.61.8-0.91.0-0.51.9-0.40.20.4-2.01.90.42.31.70.81.62.21.62.42.01.5
Distance moved, locomotor task time 11.72.57.1-1.3-1.11.4-1.6-1.70.7-0.60.1-1.70.1-0.2-0.41.8-1.9-0.9-2.4-1.6-0.4-1.7-2.5-2.0-2.7-2.5-1.9
Vertical activity count, locomotor time 10.30.72.5-0.2-0.40.4-0.2-0.90.1-0.1-0.2-0.8-0.60.60.31.0-1.0-0.9-1.0-0.8-0.0-0.8-1.0-1.2-1.3-1.6-1.1
Time >=10cm from walls, locomotor time 20.30.41.70.30.7-0.50.40.1-0.50.9-0.80.3-0.70.60.6-0.40.0-1.1-0.10.70.90.5-0.4-0.9-0.50.0-1.3
Bouts of movement, locomotor time 21.62.55.21.82.0-1.71.82.1-0.71.0-0.81.3-1.01.21.2-2.32.1-0.12.01.70.72.11.90.61.82.11.4
Total resting periods, locomotor time 20.81.53.31.21.4-1.11.41.6-0.10.4-0.20.8-0.20.50.6-1.81.50.51.61.10.21.61.81.01.71.81.5
Rest time, locomotor task time 20.60.82.40.0-0.00.10.70.40.3-0.80.60.41.3-0.6-0.6-0.60.61.50.80.0-0.80.61.61.61.30.71.4
Distance moved, locomotor task time 21.31.55.7-0.4-0.10.1-0.7-0.7-0.51.0-1.0-0.5-1.30.60.90.7-0.7-2.0-1.40.01.1-0.7-2.2-2.4-2.2-1.1-2.2
Vertical activity count, locomotor time 20.70.93.50.40.6-0.90.70.2-0.61.4-1.10.3-1.81.21.4-0.20.0-1.90.00.91.30.2-0.6-1.4-0.7-0.2-1.1
Light reinforcement 10.30.72.31.00.8-1.01.00.9-0.40.8-0.20.7-0.5-0.00.2-1.00.8-0.11.40.90.50.51.51.01.40.50.6
Light reinforcement 23.75.89.22.83.0-2.92.52.7-2.62.6-2.42.9-2.22.12.1-2.92.9-1.52.82.52.42.72.30.02.21.40.4
Bone: marrow area3.57.611.53.23.3-3.33.13.1-3.23.3-3.33.4-2.92.73.1-3.23.2-2.52.63.02.62.51.6-1.01.60.6-0.2
Bone: maximum diameter1.32.44.92.21.7-1.72.02.0-1.41.1-1.61.7-1.21.51.3-1.72.0-0.41.91.30.91.61.90.31.71.20.6
Bone: maximum force0.30.61.41.00.9-0.70.80.9-0.90.6-1.00.8-0.91.11.2-0.60.6-0.70.40.50.60.60.2-0.60.1-0.5-0.5
Bone: maximum moment0.30.51.31.00.9-0.70.90.9-0.80.6-0.90.8-0.81.01.1-0.70.7-0.50.60.50.50.60.4-0.40.3-0.4-0.3
Mean time between licks in bursts1.02.54.1-2.0-1.91.9-2.0-2.01.6-1.61.7-1.81.8-1.7-1.71.9-1.71.2-1.5-1.6-1.4-1.6-1.30.5-1.0-1.0-0.1
Mean num. licks in bursts0.71.12.8-0.8-0.91.3-1.5-0.91.1-1.71.3-1.21.2-0.6-1.30.8-0.81.3-0.9-1.6-1.2-0.5-0.50.3-0.4-0.50.4
Cd content in liver0.91.03.00.40.9-0.60.10.1-1.31.3-1.30.8-1.21.01.1-0.30.2-1.7-0.40.61.20.2-1.0-1.7-1.1-0.5-1.5
Co content in liver0.40.41.50.70.5-0.70.60.5-0.10.5-0.10.5-0.4-0.20.2-0.80.80.21.10.70.30.31.00.91.20.61.0
Cu content in liver0.20.30.6-0.5-0.80.6-0.4-0.60.7-0.70.6-0.70.2-0.4-0.10.7-0.70.4-0.5-0.5-0.6-0.7-0.30.1-0.4-0.50.1
Fe content in liver0.30.30.7-0.1-0.50.6-0.4-0.70.1-0.70.2-0.50.00.5-0.10.5-0.6-0.0-0.8-0.8-0.2-0.2-0.7-0.8-0.9-0.7-0.6
K content in liver0.30.30.60.50.3-0.70.50.4-0.60.7-0.50.6-0.60.40.3-0.30.3-0.60.60.70.80.30.4-0.00.30.5-0.4
Mg content in liver0.40.41.40.70.5-0.80.60.6-0.70.9-0.70.7-0.70.50.6-0.50.5-0.70.60.90.80.60.3-0.20.31.2-0.3
Mn content in liver0.91.03.71.30.9-1.11.21.3-0.60.8-0.51.0-0.60.50.6-1.11.1-0.21.31.10.50.91.30.61.21.90.9
Na content in liver3.33.66.92.62.1-2.22.22.3-2.11.7-2.12.2-2.02.22.2-2.12.2-1.31.81.71.52.01.5-0.61.21.40.1
Rb content in liver0.40.41.0-0.8-1.00.6-0.6-0.91.0-0.50.8-0.80.7-0.9-0.60.8-0.70.6-0.4-0.4-0.6-0.9-0.10.5-0.1-0.50.4
Se content in liver0.81.02.3-1.1-1.11.2-0.9-1.10.6-0.90.8-1.00.6-0.4-0.71.3-1.50.1-1.5-1.0-0.6-0.8-1.2-0.7-1.5-0.7-1.1
Sr content in liver0.90.81.6-1.1-1.20.9-0.8-0.71.1-0.91.1-1.01.2-1.3-1.10.8-0.81.1-0.4-0.7-0.9-0.80.20.90.1-0.20.6
Zn content in liver0.00.00.2-0.0-0.20.10.1-0.20.0-0.10.1-0.1-0.00.0-0.20.3-0.4-0.1-0.2-0.1-0.1-0.2-0.2-0.1-0.3-0.2-0.4
Bone: minimum diameter3.66.711.93.43.1-2.92.82.9-3.02.8-3.23.1-3.03.13.1-2.62.9-2.42.02.42.32.31.2-1.61.01.1-0.5
Time in familiar zone, hab. session 10.60.52.20.80.2-0.50.80.7-0.00.00.10.4-0.2-0.1-0.5-0.60.70.61.10.2-0.20.31.51.21.40.71.3
Time in novel zone, hab. session 11.31.35.7-0.30.50.0-0.6-0.3-0.90.9-0.90.2-0.70.81.10.3-0.4-1.8-1.40.21.0-0.0-2.1-2.4-2.1-0.5-2.2
Total zone transitions, hab. session 10.81.13.4-0.5-0.90.7-0.5-0.61.4-1.31.5-1.01.1-1.3-1.00.5-0.41.70.3-0.7-1.5-0.80.71.91.00.11.7
Total locomotion distance, hab. session 10.81.12.3-1.0-1.11.1-0.9-0.91.5-1.31.5-1.31.3-1.4-1.10.9-1.01.4-0.4-0.9-1.3-1.00.01.30.2-0.20.9
Locomotion velocity, hab. session 10.91.22.4-1.1-1.21.1-0.9-0.91.5-1.31.5-1.31.3-1.5-1.11.0-1.11.4-0.3-0.9-1.3-1.10.01.40.3-0.10.9
Time in familiar zone, hab. session 21.51.55.91.61.2-1.21.21.3-0.90.9-0.61.3-0.70.30.3-1.71.50.11.61.00.41.21.50.71.62.41.6
Time in novel zone, hab. session 21.11.12.7-1.3-0.91.0-1.0-1.10.6-0.50.4-1.00.5-0.2-0.01.4-1.3-0.4-1.5-0.6-0.1-1.0-1.5-1.0-1.6-1.6-1.6
Total zone transitions, hab. session 21.01.25.30.1-0.40.00.40.20.9-0.60.9-0.31.0-1.2-0.9-0.50.51.71.20.0-1.1-0.01.62.31.91.12.3
Total locomotion distance, hab. session 21.31.75.0-1.1-1.30.9-0.6-0.61.7-1.21.6-1.11.8-2.1-1.50.5-0.62.00.3-0.6-1.5-0.90.92.21.10.41.9
Locomotion velocity, hab. session 21.21.65.5-1.0-1.20.8-0.4-0.51.6-1.11.5-1.11.7-2.0-1.50.4-0.51.90.4-0.5-1.5-0.91.02.31.20.11.8
Novel to familiar place preference ratio0.50.52.4-0.8-0.40.3-0.5-0.4-0.00.3-0.1-0.4-0.10.10.60.8-0.7-0.9-1.00.00.4-0.5-1.1-1.0-1.3-1.0-1.5
Novelty place preference0.50.52.6-0.5-0.1-0.0-0.2-0.1-0.40.7-0.4-0.0-0.40.30.90.5-0.5-1.2-0.70.40.7-0.3-1.0-1.2-1.2-0.9-1.6
Time in novel zone, NPP test0.50.52.3-0.30.2-0.2-0.00.2-0.50.9-0.60.2-0.50.41.00.3-0.2-1.3-0.60.60.8-0.1-0.9-1.2-1.1-0.4-1.5
Total zone transitions, NPP test0.40.63.70.50.1-0.20.50.50.3-0.40.30.10.4-0.3-0.2-0.70.71.10.90.3-0.40.61.01.21.21.91.7
Total locomotion distance, NPP test0.10.20.6-0.6-0.50.3-0.3-0.30.6-0.30.4-0.50.8-0.7-0.40.2-0.30.6-0.0-0.1-0.3-0.30.00.60.20.40.5
Locomotion velocity, NPP test0.20.30.9-0.8-0.80.5-0.3-0.50.8-0.50.6-0.61.0-0.9-0.60.4-0.50.7-0.0-0.2-0.5-0.40.20.90.30.10.6
Intraocular pressure0.40.52.1-0.30.00.1-0.7-0.4-0.40.6-0.2-0.3-1.00.30.50.4-0.4-1.2-0.80.20.9-0.1-1.5-1.4-1.2-0.1-1.1
Delta distance traveled before/after self-admin0.60.62.10.20.4-0.81.10.90.20.90.20.4-0.2-0.9-0.1-0.60.50.01.31.10.3-0.50.91.41.4-0.40.9
Delta ambulatory time before/after self-admin0.80.93.40.50.5-1.01.41.10.31.00.30.4-0.4-0.90.2-0.60.70.11.71.10.1-0.61.31.91.8-0.41.1
Parametrial fat weight3.37.814.83.23.1-3.73.32.9-3.13.8-3.03.4-3.72.63.1-2.42.2-3.32.83.33.21.71.8-0.61.50.4-1.1
Pavlov. Cond. lever latency0.00.00.20.10.2-0.20.30.4-0.10.3-0.00.1-0.10.00.20.1-0.0-0.30.10.30.1-0.10.3-0.00.00.3-0.2
Pavlov. Cond. magazine entry latency0.50.61.4-1.2-1.10.9-0.9-1.10.9-0.80.8-0.91.0-0.8-0.70.8-0.90.5-0.8-0.6-0.6-0.6-0.80.1-0.6-0.4-0.3
Pavlov. Cond. change in total contacts0.10.10.5-0.3-0.20.2-0.1-0.10.5-0.30.2-0.20.6-0.5-0.50.10.00.60.2-0.1-0.2-0.20.20.70.5-0.20.4
Pavlov. Cond. index score0.10.10.4-0.6-0.50.4-0.4-0.70.4-0.40.3-0.40.5-0.3-0.40.3-0.40.3-0.3-0.3-0.2-0.2-0.40.1-0.2-0.6-0.2
Pavlov. Cond. latency score0.20.20.5-0.6-0.60.4-0.5-0.70.5-0.40.4-0.40.5-0.4-0.50.3-0.40.4-0.3-0.4-0.3-0.3-0.40.3-0.1-0.7-0.1
Pavlov. Cond. lever contacts0.00.00.20.0-0.10.2-0.1-0.30.0-0.4-0.1-0.00.10.2-0.0-0.10.10.3-0.1-0.3-0.10.2-0.1-0.0-0.0-0.40.1
Pavlov. Cond. magazine entry number0.20.30.80.90.8-0.50.70.9-0.40.2-0.20.5-0.60.40.4-0.50.60.00.70.30.10.40.90.20.70.50.6
Pavlov. Cond. intertrial magazine entries2.12.56.91.71.8-1.00.70.9-2.31.2-2.41.5-1.72.41.7-1.31.2-1.8-0.20.71.81.8-0.6-2.6-1.00.8-1.4
Pavlov. Cond. lever-magazine prob. diff.0.10.10.3-0.5-0.40.3-0.3-0.50.2-0.30.1-0.20.4-0.2-0.30.3-0.30.2-0.3-0.3-0.1-0.1-0.40.0-0.2-0.6-0.2
Pavlov. Cond. response bias0.20.20.6-0.6-0.60.6-0.6-0.80.4-0.50.3-0.50.6-0.3-0.40.5-0.50.3-0.5-0.5-0.3-0.2-0.6-0.1-0.4-0.3-0.2
Pavlov. Cond. lever latency1.31.83.9-1.8-1.41.5-2.0-1.81.2-0.81.1-1.51.1-1.1-0.91.5-1.70.2-1.8-1.2-0.7-1.5-1.7-0.5-1.6-1.1-0.9
Pavlov. Cond. magazine entry latency0.30.31.50.4-0.00.00.30.20.2-0.50.40.00.3-0.2-0.6-0.30.30.80.5-0.1-0.40.30.90.80.81.21.0
Pavlov. Cond. change in total contacts1.11.73.61.71.3-1.51.91.7-1.01.0-0.81.4-1.10.90.9-1.41.5-0.21.91.30.71.21.90.81.80.91.0
Pavlov. Cond. index score0.30.51.21.00.5-0.51.00.9-0.3-0.1-0.20.5-0.30.50.0-0.70.80.40.90.2-0.10.81.10.61.00.90.9
Pavlov. Cond. latency score0.30.41.30.70.2-0.30.70.7-0.0-0.30.20.30.10.1-0.3-0.50.60.70.80.1-0.30.61.10.81.11.01.1
Pavlov. Cond. lever contacts1.42.04.31.91.5-1.62.11.9-1.31.0-1.21.6-1.21.31.0-1.61.7-0.41.81.20.81.51.70.41.61.00.9
Pavlov. Cond. magazine entry number0.30.31.0-0.6-0.40.5-0.7-0.50.2-0.20.0-0.40.2-0.00.20.6-0.7-0.3-0.9-0.4-0.1-0.5-0.9-0.7-1.0-0.9-0.9
Pavlov. Cond. intertrial magazine entries0.20.30.70.70.6-0.50.30.5-0.70.4-0.80.5-0.60.90.6-0.50.4-0.60.10.30.60.5-0.0-0.6-0.10.3-0.5
Pavlov. Cond. lever-magazine prob. diff.0.40.51.61.00.4-0.51.00.8-0.2-0.2-0.00.5-0.20.4-0.1-0.70.80.61.00.2-0.10.71.30.81.21.01.0
Pavlov. Cond. response bias1.21.73.61.81.3-1.51.91.7-1.20.8-1.11.4-1.11.20.8-1.41.6-0.31.71.10.71.31.70.41.50.90.8
Time in closed arm before self-admin0.50.61.90.91.0-0.71.01.0-0.80.7-0.51.00.30.30.6-1.11.0-0.10.80.80.21.01.00.20.71.40.3
Time in closed arm after self-admin1.51.64.20.91.2-1.61.81.3-1.02.1-1.01.5-0.6-0.50.5-1.21.2-0.81.81.91.00.01.81.11.6-0.00.4
Time in open arm before self-admin0.10.20.9-0.2-0.2-0.00.40.10.4-0.10.1-0.20.3-0.5-0.40.10.00.40.50.1-0.2-0.20.70.90.7-0.60.3
Time in open arm after self-admin0.30.41.90.70.5-0.3-0.10.4-0.4-0.0-0.40.2-1.11.40.9-0.30.5-0.4-0.00.00.40.9-0.2-0.9-0.20.8-0.2
Bone: periosteal estimation1.53.25.82.42.2-2.12.22.2-1.91.8-2.22.1-1.72.02.1-2.02.2-1.31.81.71.31.61.3-0.51.20.40.0
Bone: periosteal perimeter0.91.63.51.91.4-1.41.81.8-1.00.7-1.21.3-0.81.31.1-1.31.6-0.21.70.90.41.21.70.41.50.50.7
Bone: post-yield work0.50.81.81.11.1-0.91.00.9-1.00.6-1.10.9-1.11.31.2-0.70.6-0.80.60.40.60.60.6-0.60.2-1.3-0.4
Progressive ratio test 1 active lever presses2.12.65.6-1.9-2.31.7-1.8-2.42.1-1.82.0-1.71.6-1.9-1.51.8-1.31.7-0.9-1.4-1.5-1.7-0.61.3-0.1-0.60.8
Progressive ratio test 1 breakpoint1.92.45.2-1.8-2.31.6-1.8-2.32.0-1.71.9-1.61.6-1.8-1.41.7-1.21.7-0.8-1.3-1.4-1.6-0.61.3-0.0-0.50.8
Progressive ratio test 1 inactive lever presses2.94.28.1-2.3-2.42.5-2.5-2.92.0-2.32.1-2.12.2-1.9-2.12.3-2.31.6-2.3-2.2-1.9-1.9-1.80.1-1.6-1.30.0
Progressive ratio test 2 active lever presses3.74.37.1-2.4-2.52.7-2.5-2.62.2-2.62.1-2.32.4-1.9-2.12.4-2.02.0-2.2-2.3-2.1-1.9-1.60.3-1.4-0.90.0
Progressive ratio test 2 breakpoint3.54.06.7-2.3-2.42.6-2.5-2.52.1-2.52.1-2.22.3-1.8-2.02.3-2.01.9-2.2-2.2-2.0-1.8-1.60.2-1.4-0.9-0.0
Progressive ratio test 2 inactive lever presses2.74.410.3-2.0-2.22.8-2.0-2.12.3-3.22.2-2.32.9-1.9-2.71.6-1.42.9-2.0-2.5-2.7-1.1-0.80.6-0.80.11.1
Incentive Sensitization - Responses1.31.94.0-1.4-1.22.0-1.7-1.21.1-1.90.9-1.22.0-1.0-1.51.4-1.11.3-1.9-1.8-1.5-0.9-1.2-0.5-1.4-0.2-0.2
Incentive Sensitization - Breakpoint1.52.04.3-1.4-1.22.1-1.7-1.21.2-2.01.0-1.32.1-1.0-1.61.3-1.11.5-2.0-1.8-1.6-0.8-1.2-0.5-1.4-0.1-0.1
Sum of active levers in priming session hrs 5-60.20.20.5-0.4-0.40.5-0.3-0.30.1-0.60.0-0.20.50.2-0.60.4-0.70.2-0.6-0.7-0.20.1-0.2-0.3-0.6-0.1-0.6
Progressive ratio0.30.41.20.10.5-0.2-0.6-0.3-0.50.4-0.60.3-0.70.91.1-0.20.0-0.9-0.40.30.80.5-1.0-1.1-0.7-0.3-1.0
Food seeking constrained by brief footshock0.91.23.4-1.2-1.21.1-0.7-1.20.7-1.01.4-1.20.9-1.0-0.61.6-1.50.5-0.8-0.9-1.1-1.7-0.50.6-0.6-1.9-0.4
Seeking ratio, punishment vs. effort0.50.81.7-1.0-1.21.0-0.1-0.70.5-0.81.0-0.81.1-1.2-1.11.1-1.10.8-0.7-0.9-1.1-1.30.00.6-0.4-0.80.1
Retroperitoneal fat weight1.87.612.53.53.2-3.52.72.9-3.03.5-3.13.4-3.22.42.9-2.92.9-2.63.03.13.02.11.9-0.41.91.3-0.2
Reaction time number correct0.00.10.20.40.4-0.20.30.40.1-0.2-0.0-0.0-0.30.50.3-0.00.50.10.30.1-0.20.00.30.00.3-0.20.4
Reaction time mean minus median0.30.72.1-0.9-0.51.2-0.9-0.80.6-1.20.7-0.91.3-0.8-1.40.1-0.71.0-1.0-1.0-0.70.1-0.40.0-0.60.40.2
Reaction time mean minus median AUC0.10.31.2-0.30.10.7-0.4-0.30.1-1.00.1-0.40.9-0.2-1.1-0.4-0.00.9-0.6-0.8-0.40.7-0.0-0.1-0.20.70.4
Reaction time num false alarms2.23.15.3-2.2-2.01.9-1.5-1.82.0-1.61.9-2.31.7-1.6-1.72.3-2.20.9-1.6-1.8-1.7-2.1-1.10.4-1.2-2.3-0.9
Reaction time num false alarms AUC1.82.84.7-2.0-1.91.7-1.3-1.62.0-1.52.1-2.21.6-1.7-1.72.1-2.21.0-1.2-1.5-1.6-2.1-0.70.9-0.8-2.2-0.5
Reaction time trials correct on left0.00.10.20.40.4-0.20.30.40.1-0.2-0.0-0.0-0.30.50.3-0.00.50.10.30.1-0.20.00.30.00.3-0.20.4
Reaction time trials on left0.00.10.30.50.4-0.20.30.50.1-0.1-0.00.0-0.40.50.4-0.10.50.10.30.1-0.20.10.30.00.3-0.20.4
Reaction time mean0.30.51.9-0.80.10.4-0.8-0.7-0.70.3-0.5-0.00.1-0.0-0.30.1-0.5-0.8-1.1-0.20.60.1-1.4-1.3-1.4-0.5-1.3
Reaction time mean AUC0.30.51.8-0.8-0.00.6-0.8-0.8-0.5-0.0-0.3-0.20.3-0.0-0.50.2-0.6-0.5-1.2-0.50.30.1-1.3-1.2-1.3-0.3-1.1
Median of all reaction times0.50.72.5-0.60.3-0.0-0.6-0.6-1.00.9-0.90.4-0.30.30.20.0-0.3-1.3-0.90.11.10.1-1.5-1.6-1.4-0.7-1.6
Reaction time omissions0.10.10.5-0.30.00.4-0.5-0.3-0.1-0.0-0.2-0.00.1-0.3-0.5-0.50.0-0.0-0.6-0.20.10.3-0.7-0.6-0.60.30.0
Reaction time false alarm rate2.02.75.1-2.2-2.01.7-1.5-1.81.9-1.31.9-2.11.6-1.8-1.72.0-2.30.8-1.4-1.5-1.4-1.9-0.90.7-0.9-2.0-0.7
Reaction time premature initiation rate1.42.05.11.41.7-1.51.21.7-1.21.4-1.21.8-0.50.81.3-1.91.4-0.51.61.81.41.71.30.41.32.30.6
Reaction time premature initiations0.91.64.21.41.7-1.31.21.7-0.90.9-1.01.5-0.50.91.2-1.71.4-0.31.41.51.11.61.20.41.22.00.7
Std. dev. reaction times0.50.92.1-1.3-0.61.3-1.3-1.20.5-1.00.6-1.01.1-0.8-1.30.4-1.10.5-1.4-1.1-0.5-0.3-1.2-0.5-1.2-0.4-0.3
Reaction time trials completed0.00.10.30.50.4-0.20.30.50.1-0.1-0.00.0-0.40.50.4-0.10.50.10.30.1-0.20.10.30.00.3-0.20.4
Reaction time trials AUC0.10.20.70.70.6-0.50.60.7-0.20.2-0.30.3-0.70.80.7-0.20.7-0.20.40.30.10.20.3-0.20.3-0.20.2
Run reversals in cocaine runway, females0.90.93.4-1.1-0.61.1-0.6-0.60.8-1.10.9-1.01.9-1.3-1.80.2-0.51.4-0.7-0.8-1.0-0.0-0.10.5-0.20.50.6
Run reversals in cocaine runway, males0.50.52.30.80.5-0.21.10.90.1-0.40.2-0.00.1-0.1-0.5-0.60.60.90.9-0.0-0.60.41.51.01.20.51.1
Latency to leave start box in cocaine runway0.10.10.40.00.3-0.3-0.00.40.00.3-0.10.2-0.1-0.3-0.2-0.60.20.00.40.20.30.10.30.50.5-0.30.5
Latency to leave start box in cocaine runway, F0.10.10.6-0.4-0.00.1-0.4-0.10.10.30.2-0.1-0.0-0.6-0.3-0.0-0.3-0.3-0.20.00.3-0.4-0.40.0-0.2-0.8-0.1
Latency to leave start box in cocaine runway, M0.50.51.40.70.4-0.50.50.7-0.20.0-0.40.7-0.10.2-0.0-1.00.80.51.00.2-0.00.81.10.81.20.61.1
Std. dev. time between licks in bursts0.40.51.6-0.6-0.81.0-0.7-0.70.8-1.30.4-0.90.9-0.4-0.90.7-0.60.9-0.8-1.1-1.0-0.4-0.50.0-0.50.10.1
Total sessions with >9 infusions0.70.81.6-1.2-1.21.0-1.0-1.20.6-0.50.4-0.90.3-0.8-0.81.3-1.1-0.1-1.2-0.9-0.3-1.2-1.2-0.6-1.2-0.9-0.8
Short access day 1 total inactive lever presses2.02.75.9-2.1-1.62.1-2.4-2.01.2-1.61.3-1.71.5-1.0-1.11.7-2.00.6-2.4-1.7-1.0-1.0-2.2-0.9-2.1-0.7-1.2
Short access day 10 total inactive lever presses0.41.05.0-0.5-0.00.7-1.7-1.1-0.5-0.0-0.3-0.1-0.10.40.30.2-0.5-0.8-1.7-0.60.30.2-2.2-2.1-1.90.1-1.3
Short access day 1 total infusions1.11.53.4-1.5-1.31.1-1.2-1.80.7-0.40.7-1.10.6-0.8-0.71.8-1.5-0.4-1.5-1.0-0.4-1.7-1.6-0.7-1.6-1.5-1.5
Short access day 10 total infusions0.60.82.7-1.1-1.10.6-1.4-1.50.4-0.10.3-0.6-0.4-0.40.01.1-1.0-0.6-1.1-0.40.2-1.1-1.7-0.8-1.2-0.7-1.0
Short access total infusions0.81.02.9-1.1-1.20.8-1.3-1.70.7-0.30.4-0.80.0-0.6-0.41.3-1.1-0.3-1.2-0.7-0.1-1.4-1.6-0.6-1.2-1.0-0.8
Short access day 1 locomotion1.82.35.3-2.3-1.71.8-1.5-1.51.1-1.01.3-1.51.2-1.4-1.51.9-2.10.2-2.1-1.2-0.9-1.4-1.6-0.7-1.9-1.2-1.3
Short access day 10 total locomotion0.10.20.70.20.2-0.10.20.5-0.20.0-0.10.7-0.2-0.3-0.3-0.80.40.40.50.20.20.40.60.50.60.70.7
Short access total locomotion0.10.10.7-0.6-0.50.6-0.3-0.10.3-0.40.3-0.20.1-0.6-0.8-0.0-0.40.3-0.5-0.4-0.2-0.1-0.2-0.0-0.30.20.1
One hour access (0.3 mA shock)1.92.24.8-1.4-1.72.0-2.0-1.31.6-2.21.3-1.81.7-1.4-1.71.4-0.71.9-1.5-1.8-1.7-0.9-0.80.2-0.70.60.8
Compulsive drug intake0.80.91.91.21.2-1.11.31.4-1.21.0-1.11.1-0.70.60.7-1.11.2-0.51.01.00.61.01.0-0.00.70.90.4
One hour access (shock baseline)2.53.87.5-2.0-2.22.6-2.7-2.22.1-2.61.8-2.21.9-1.4-1.92.2-1.71.8-2.3-2.4-1.9-1.5-1.7-0.2-1.5-0.6-0.1
Social response proportion0.70.81.8-1.1-1.00.8-0.9-0.81.4-1.01.3-1.01.3-1.2-1.20.3-1.01.1-0.3-0.7-0.6-0.50.11.10.2-0.40.8
Social responses0.60.82.9-0.3-0.80.3-0.1-0.41.3-0.71.3-0.70.6-1.0-0.80.2-0.71.10.5-0.4-0.9-1.00.81.70.9-1.11.2
Social time0.20.21.11.00.3-0.40.30.2-0.00.1-0.10.1-0.80.30.2-0.60.50.00.6-0.00.10.10.60.20.60.70.9
Soleus weight1.23.67.12.62.1-2.22.72.2-1.71.8-1.72.3-1.71.71.9-2.32.2-0.92.21.91.21.92.10.21.81.30.8
Bone: stiffness0.00.00.20.30.2-0.10.30.4-0.1-0.1-0.10.10.00.20.20.00.00.10.20.0-0.10.10.50.20.2-0.4-0.2
Tibialis anterior weight6.220.934.75.15.3-5.04.64.5-5.95.6-5.85.5-5.95.55.5-4.44.1-5.52.74.44.93.91.1-3.90.40.6-2.3
Time to tail flick, vehicle, before self-admin2.42.56.3-1.5-1.61.7-1.4-2.00.9-1.31.0-1.01.2-0.6-1.02.3-2.40.0-2.1-1.8-1.0-2.0-1.7-0.8-2.0-2.5-1.4
Time to tail flick, vehicle, after self-admin0.71.02.80.91.4-1.00.81.0-1.01.1-1.11.0-0.40.40.5-1.31.5-0.40.81.21.11.40.7-0.20.71.70.3
Time to tail flick, test, before self-admin1.01.03.8-1.3-1.00.9-0.8-1.01.1-0.61.3-1.01.1-2.0-1.80.6-1.01.0-0.3-0.5-0.7-1.00.21.20.1-0.60.3
Time to tail flick, test, after self-admin0.60.72.7-0.1-0.30.10.60.30.7-0.30.9-0.20.6-1.4-1.1-0.10.11.10.7-0.1-1.0-0.71.31.61.2-0.51.2
Delta time to tail flick, vehicle, before/after SA2.22.16.81.51.7-1.41.11.6-1.01.2-1.21.1-0.90.60.8-2.22.4-0.11.61.51.12.01.20.21.52.61.1
Delta time to tail flick, test, before/after SA0.10.10.30.50.2-0.20.30.6-0.1-0.00.00.3-0.50.40.4-0.10.40.00.3-0.0-0.20.10.1-0.00.30.10.4
Tibia length0.00.10.5-0.4-0.20.3-0.3-0.50.4-0.20.1-0.40.4-0.4-0.10.3-0.10.3-0.2-0.1-0.2-0.3-0.20.2-0.0-0.7-0.0
Ambulatory time before self-admin0.30.51.70.60.7-0.2-0.10.5-1.30.3-0.90.6-0.81.1-0.1-0.30.5-0.7-0.3-0.10.71.1-0.2-1.3-0.61.0-0.6
Ambulatory time after self-admin0.50.61.90.70.9-1.00.71.1-1.11.2-0.80.8-1.40.50.3-0.60.7-1.00.80.81.10.40.3-0.20.40.5-0.4
Bone: tissue strength0.40.41.0-0.7-0.70.7-0.7-0.50.7-0.60.8-0.60.9-1.0-0.70.5-0.50.8-0.3-0.4-0.6-0.4-0.30.60.00.10.3
Total heroin consumption0.80.93.0-0.2-0.70.5-0.70.31.1-1.31.3-0.60.8-0.8-1.3-0.0-0.01.70.5-0.9-1.0-0.21.01.71.20.31.6
Bone: trabecular number0.10.10.40.30.6-0.50.50.5-0.50.6-0.20.6-0.40.10.3-0.30.2-0.40.40.50.40.20.3-0.00.20.0-0.0
Bone: trabecular spacing2.53.35.9-2.1-2.12.0-2.1-1.82.3-2.12.1-2.12.4-2.4-2.31.4-1.42.3-1.1-1.6-1.8-1.3-0.61.5-0.10.11.1
Bone: trabecular thickness0.91.12.21.11.2-1.21.51.1-1.21.3-1.21.2-1.41.31.4-0.70.8-1.30.71.11.10.60.5-0.70.2-0.2-0.6
Bone: trabecular tissue density0.81.22.8-0.8-1.10.8-0.3-0.41.5-1.11.4-1.01.5-1.6-1.30.8-0.71.50.0-0.7-1.4-1.20.71.70.7-0.01.1
Water consumed over 24 hours0.40.51.4-0.5-0.80.6-0.4-0.61.0-1.01.2-0.80.5-0.6-0.70.6-0.70.9-0.1-0.7-0.8-0.60.20.90.2-0.30.5
Number of responses in last shaping day1.71.94.7-1.8-1.51.5-1.1-1.31.3-1.21.9-1.42.0-2.2-1.81.2-1.41.4-0.9-1.1-1.4-1.3-0.31.1-0.2-0.90.0