Hub : Genes

Cbr1l2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression Cbr1l2 0.15 0.07 6.8e-14 0.16 0.17 0.17 0.17 1.4e-12 1.6e-13 5.0e-14 4.8e-14
2 Brain intron excision ratio chr11_46346786_46347257 0.06 0.03 1.2e-06 0.06 0.07 0.07 0.07 4.8e-06 4.7e-07 4.6e-07 3.4e-07
3 Liver gene expression Cbr1l2 0.22 0.09 0.0e+00 0.21 0.23 0.22 0.22 1.3e-22 5.7e-25 2.2e-24 3.0e-24
4 RMTg gene expression Cbr1l2 0.27 0.14 2.0e-06 0.26 0.24 0.25 0.25 2.0e-07 5.7e-07 3.0e-07 3.1e-07
5 BLA intron excision ratio chr11_46346786_46347257 0.05 0.04 6.5e-03 0.05 0.02 0.04 0.04 1.1e-03 3.3e-02 5.7e-03 4.3e-03
6 NAcc intron excision ratio chr11_46379646_46380552 0.09 0.04 1.0e-13 0.09 0.08 0.08 0.08 4.7e-13 1.6e-12 4.2e-12 1.1e-12
7 pVTA intron excision ratio chr11_46363568_46364473 0.23 0.09 0.0e+00 0.16 0.24 0.22 0.22 3.8e-13 5.4e-19 5.0e-18 1.6e-17
8 pVTA intron excision ratio chr11_46347364_46348270 0.07 0.05 7.2e-04 0.04 0.02 0.03 0.04 1.4e-04 6.2e-03 3.1e-03 1.7e-04
9 PL intron excision ratio chr11_46363568_46364473 0.04 0.03 4.8e-05 0.04 0.05 0.04 0.05 6.6e-05 8.6e-06 1.3e-05 4.9e-06
10 PL intron excision ratio chr11_46379646_46380552 0.03 0.02 1.6e-03 0.02 0.02 0.01 0.02 1.2e-03 2.9e-03 2.8e-02 3.7e-03
11 IC intron excision ratio chr11_46362976_46363461 0.1 0.07 9.9e-03 0.03 0.03 0 0.02 2.9e-02 2.0e-02 2.8e-01 5.4e-02
12 BLA intron excision ratio chr11_46363568_46364473 0.05 0.03 5.5e-03 0.04 0.03 0.01 0.03 4.3e-03 1.1e-02 8.3e-02 1.0e-02
13 Brain intron excision ratio chr11_46347364_46348270 0.06 0.04 8.9e-06 0.05 0.04 0.04 0.04 2.9e-05 4.8e-05 5.7e-05 2.9e-04
14 NAcc gene expression Cbr1l2 0.15 0.07 0.0e+00 0.13 0.11 0.12 0.06 3.1e-19 1.2e-16 9.0e-18 1.3e-09
15 pVTA intron excision ratio chr11_46379646_46380552 0.09 0.04 3.0e-05 0.05 0.06 0.05 0.05 1.3e-04 2.1e-05 3.8e-05 6.7e-05
16 LHb intron excision ratio chr11_46379646_46380552 0.17 0.11 9.7e-03 0.01 0.04 -0 0.01 2.3e-01 3.9e-02 3.7e-01 1.5e-01
17 Brain intron excision ratio chr11_46363568_46364473 0.15 0.07 1.3e-15 0.13 0.16 0.17 0.15 6.7e-12 4.5e-15 9.9e-16 4.7e-14
18 NAcc intron excision ratio chr11_46363568_46364473 0.17 0.07 0.0e+00 0.19 0.19 0.22 0.2 6.2e-28 3.0e-28 3.1e-33 2.3e-30
19 Adipose gene expression Cbr1l2 0.94 0.01 0.0e+00 0.51 0.59 0.61 0.61 1.0e-64 4.7e-81 8.0e-86 8.8e-86
20 Eye intron excision ratio chr11_46379646_46380552 0.46 0.16 4.8e-03 0.03 0.06 0.06 0.07 1.1e-01 5.2e-02 3.9e-02 2.8e-02
21 Brain intron excision ratio chr11_46379646_46380552 0.08 0.04 1.2e-04 0.03 0.04 0.03 0.03 6.9e-04 2.0e-04 2.1e-03 1.2e-03
22 Adipose mRNA stability Cbr1l2 0.17 0.08 2.8e-15 0.08 0.11 0.11 0.1 6.5e-09 1.5e-12 5.6e-12 1.9e-11
23 Brain mRNA stability Cbr1l2 0.03 0.02 6.3e-03 0.03 0.02 0.05 0.03 7.9e-04 2.6e-03 3.3e-05 5.9e-04
24 NAcc mRNA stability Cbr1l2 0.07 0.04 4.3e-06 0.04 0.03 0.03 0.04 1.3e-06 1.9e-05 2.8e-05 4.1e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density0.10.10.50.00.4-0.4-0.3-0.20.40.70.30.40.50.1-0.4-0.0-0.0-0.70.1-0.5-0.50.0-0.2-0.3-0.20.40.5
Area under the delay curve0.30.41.80.00.2-0.4-0.4-0.3-0.50.3-0.50.2-0.3-0.80.20.7-0.60.50.8-0.70.1-0.10.71.11.0-1.0-1.3
BMI with tail0.41.42.81.31.3-1.6-1.5-1.31.41.71.21.31.50.9-1.11.0-1.1-1.31.4-1.4-1.2-0.51.1-0.00.90.40.1
BMI without tail0.00.10.40.00.3-0.3-0.2-0.30.10.60.10.00.5-0.20.2-0.10.0-0.50.2-0.4-0.40.30.40.00.10.10.2
Body weight0.10.31.40.40.2-0.6-0.3-0.6-0.10.2-0.20.00.3-0.2-0.10.1-0.30.11.1-0.40.00.51.21.21.21.0-0.5
Weight adjusted by age0.30.82.1-1.0-0.90.80.40.4-1.4-1.1-1.4-1.0-1.1-1.31.1-0.70.81.3-0.10.51.00.70.31.40.50.4-0.9
Bone surface3.97.612.03.33.5-3.3-3.2-3.43.03.03.13.43.12.8-3.13.0-3.2-2.22.7-2.8-2.4-2.61.9-0.81.8-1.1-0.3
Bone volume2.04.06.32.32.5-2.4-2.4-2.42.22.32.22.52.32.0-2.22.1-2.3-1.72.0-2.2-1.9-1.81.4-0.61.2-0.7-0.0
Breakpoint value in progressive ratio session0.20.31.80.50.6-0.30.0-1.10.40.00.50.8-0.20.4-0.00.6-0.70.20.4-0.1-0.4-1.00.60.00.4-1.3-0.5
Number of licking bursts0.20.51.1-1.0-0.90.70.60.9-0.6-0.3-0.6-0.7-0.4-0.80.4-0.91.0-0.0-0.80.30.30.9-0.8-0.1-0.70.80.4
Context. condit. distance diff. score0.70.93.10.80.2-0.4-0.8-0.7-0.5-0.4-0.40.1-0.0-0.2-0.20.6-0.91.11.3-0.30.5-0.31.81.61.7-1.6-1.7
Locomotion velocity, session 10.10.10.70.20.0-0.00.20.10.20.10.10.10.30.4-0.4-0.10.1-0.4-0.3-0.1-0.4-0.2-0.6-0.5-0.4-0.90.6
Locomotion distance, session 10.81.05.71.40.9-0.9-0.9-0.80.90.40.71.11.01.0-0.91.2-1.2-0.20.9-0.7-0.6-1.20.7-0.10.7-2.4-0.7
Locomotion velocity, session 20.20.20.70.50.4-0.4-0.7-0.50.20.00.30.3-0.10.3-0.10.4-0.50.30.7-0.3-0.0-0.50.80.60.8-0.1-0.4
Locomotion distance, session 20.20.20.90.20.2-0.3-0.4-0.4-0.10.1-0.00.2-0.1-0.3-0.00.5-0.40.40.7-0.5-0.1-0.50.70.80.9-0.9-0.8
Locomotion velocity, session 32.83.27.52.32.2-1.8-1.7-2.02.11.52.41.92.02.7-2.41.7-2.0-1.71.0-1.4-1.5-2.00.4-1.60.3-1.40.6
Locomotion distance, session 30.81.02.21.00.9-1.0-0.5-0.71.01.21.20.91.31.2-1.50.6-0.8-1.40.3-0.9-1.1-0.7-0.3-1.1-0.2-1.40.7
Stereotopy head waving bouts, day 31.92.310.4-0.40.20.40.70.71.10.41.10.00.71.5-0.8-1.01.0-2.1-2.00.4-1.00.1-2.5-3.1-2.81.13.2
Stereotopy head waving duration, day 31.11.36.1-0.20.20.20.40.51.00.41.00.20.71.3-0.6-0.70.6-1.7-1.40.2-1.0-0.2-1.9-2.4-2.10.92.5
Locomotion velocity, session 70.80.91.7-1.2-1.31.11.11.0-1.2-1.1-1.3-1.2-0.7-1.01.1-1.11.10.9-0.80.90.90.9-0.70.5-0.4-0.3-0.1
Locomotion distance, session 70.81.02.5-0.9-1.20.80.80.6-1.3-1.0-1.5-1.0-0.8-1.61.3-0.80.71.3-0.00.51.10.80.31.50.6-0.7-0.9
Stereotopy head waving bouts, day 70.91.14.11.31.2-0.9-0.9-0.81.20.71.50.91.22.0-1.40.6-0.8-1.20.2-0.3-1.0-0.90.0-1.4-0.30.51.0
Stereotopy head waving duration, day 71.01.23.71.71.5-1.2-1.3-1.31.00.51.31.11.21.9-1.31.1-1.2-0.61.0-0.4-0.7-1.10.9-0.60.60.1-0.0
Locomotion velocity, session 82.32.86.02.32.0-1.9-1.8-1.81.81.41.91.82.22.5-2.31.5-1.7-1.51.4-1.4-1.5-1.70.7-0.80.8-1.40.4
Locomotion distance, session 80.81.24.10.90.2-0.7-0.9-0.9-0.3-0.1-0.10.30.1-0.2-0.30.9-1.11.11.6-0.60.3-0.61.91.82.0-1.9-2.0
Degree of sensitization distance1.41.53.4-1.3-1.41.20.80.8-1.4-1.5-1.8-1.2-1.4-1.71.7-1.01.01.7-0.31.01.60.90.41.60.40.9-1.0
Degree of sensitization stereotypy1.71.94.12.01.7-1.6-1.7-1.61.21.01.61.41.41.9-1.61.6-1.7-0.81.5-0.9-1.0-1.31.4-0.31.1-0.0-0.3
Conditioned locomotion0.70.92.0-1.1-1.11.20.90.7-1.0-1.2-0.9-1.1-1.4-1.01.2-0.91.01.1-0.81.01.10.6-0.30.5-0.40.2-0.0
Cocaine response after cond. corrected0.10.20.60.20.00.20.10.2-0.4-0.8-0.4-0.2-0.30.10.4-0.1-0.10.80.10.40.6-0.10.30.50.4-0.5-0.7
Cocaine response after cond. not corrected0.20.31.20.2-0.10.30.0-0.0-0.6-0.9-0.6-0.4-0.4-0.10.4-0.1-0.11.00.20.50.9-0.00.50.70.5-0.7-1.1
Cocaine response before conditioning0.20.20.80.30.2-0.2-0.4-0.8-0.10.1-0.10.20.1-0.20.00.5-0.40.30.5-0.30.2-0.20.80.50.6-0.7-0.9
Saline control response1.11.53.41.81.6-1.1-1.5-1.41.50.81.41.41.01.4-0.81.5-1.4-0.60.9-0.8-0.7-1.60.9-0.60.6-1.8-0.3
Bone: connectivity density0.91.42.61.21.5-1.5-1.2-1.21.41.61.31.51.61.1-1.61.2-1.2-1.31.0-1.4-1.3-0.90.5-0.50.5-0.10.1
Bone: cortical apparent density0.00.00.5-0.0-0.10.0-0.1-0.10.0-0.1-0.10.0-0.1-0.10.3-0.00.10.10.10.0-0.1-0.10.20.20.1-0.7-0.2
Bone: cortical area0.30.41.51.00.7-0.5-0.9-1.10.2-0.20.40.40.10.6-0.50.5-0.80.50.9-0.20.2-0.51.20.61.0-0.4-0.7
Bone: cortical porosity0.50.51.3-0.9-0.80.80.60.6-0.9-0.7-0.8-0.9-0.9-1.21.0-0.60.70.8-0.50.50.70.7-0.20.5-0.2-0.0-0.2
Bone: cortical porosity0.40.51.1-0.8-0.70.80.60.5-0.9-0.7-0.8-0.8-0.9-1.10.9-0.50.60.8-0.50.60.80.6-0.20.5-0.10.1-0.3
Bone: cortical thickness1.42.35.4-1.3-1.51.71.21.0-2.1-2.3-1.9-1.9-2.0-1.41.6-1.61.32.2-0.71.71.91.20.21.50.20.1-1.0
Bone: cortical thickness0.40.50.9-0.8-0.80.90.90.6-0.9-0.9-0.7-0.9-0.9-0.80.6-0.60.70.8-0.60.60.60.6-0.20.4-0.3-0.1-0.3
Bone: cortical tissue density0.00.00.5-0.0-0.0-0.0-0.0-0.10.10.0-0.00.1-0.0-0.10.2-0.00.1-0.00.0-0.0-0.1-0.10.10.10.0-0.7-0.1
Condit. Reinf. active minus inactive responses0.10.10.2-0.3-0.10.30.30.5-0.2-0.20.2-0.2-0.3-0.20.2-0.10.00.2-0.40.20.0-0.0-0.5-0.2-0.30.10.0
Condit. Reinf. active-inactive response ratio0.30.30.7-0.7-0.60.70.50.7-0.5-0.7-0.4-0.6-0.7-0.40.5-0.50.50.5-0.60.60.50.3-0.40.0-0.40.80.0
Condit. Reinf. active responses0.00.10.40.10.20.10.20.2-0.1-0.10.30.0-0.2-0.1-0.20.3-0.40.30.0-0.1-0.0-0.3-0.2-0.00.1-0.6-0.4
Condit. Reinf. inactive responses0.10.11.10.50.3-0.20.1-0.10.40.20.50.30.30.4-0.60.4-0.4-0.2-0.0-0.1-0.2-0.2-0.3-0.4-0.1-1.1-0.1
Incentive salience index mean0.10.10.6-0.5-0.50.40.40.8-0.5-0.4-0.1-0.4-0.6-0.50.3-0.20.10.5-0.20.20.20.1-0.20.30.00.1-0.3
Condit. Reinf. lever presses0.30.41.1-0.5-0.80.50.40.9-0.8-0.8-0.6-0.6-0.9-0.80.5-0.20.11.10.00.40.60.10.20.90.50.1-0.8
Condit. Reinf. active minus inactive responses1.21.84.51.61.1-1.3-1.6-1.70.70.60.61.20.60.7-0.81.6-1.70.31.8-1.2-0.4-1.51.91.01.9-2.1-1.5
Condit. Reinf. active-inactive response ratio0.40.61.60.60.4-0.7-0.9-0.90.10.40.10.60.0-0.2-0.20.9-0.90.41.1-0.9-0.1-0.61.11.01.3-1.3-1.1
Condit. Reinf. active responses1.21.73.71.91.5-1.3-1.7-1.81.20.71.21.41.11.5-1.21.6-1.6-0.41.4-1.0-0.7-1.61.4-0.01.1-1.6-0.6
Condit. Reinf. inactive responses0.71.02.81.61.3-1.0-1.3-1.41.20.51.21.11.11.7-1.11.0-1.0-0.70.7-0.4-0.5-1.00.8-0.70.3-0.20.3
Condit. Reinf. lever presses0.81.12.21.51.0-1.2-1.4-1.31.10.71.01.31.01.2-0.81.2-1.2-0.41.2-0.9-0.8-1.31.10.11.0-1.1-0.2
Condit. Reinf. lever reinforcers received1.52.14.42.11.6-1.5-1.9-1.91.30.91.31.61.21.6-1.31.7-1.8-0.41.6-1.2-0.8-1.71.60.11.4-1.7-0.7
Conditioned reinforcement - actives0.31.43.7-1.1-1.51.00.80.7-1.9-1.3-1.3-1.2-1.1-1.61.3-1.10.51.6-0.00.81.31.20.41.60.7-0.2-1.4
Conditioned reinforcement - inactives1.74.78.6-2.3-2.72.72.92.6-2.5-2.9-2.4-2.6-2.3-1.82.1-2.21.92.3-2.12.42.31.7-1.70.5-1.20.5-0.5
Conditioned locomotion0.30.40.9-0.8-0.51.00.60.5-0.6-0.9-0.3-0.7-0.7-0.60.9-0.30.50.7-0.90.60.50.0-0.3-0.2-0.6-0.7-0.0
Patch foraging indifference point 0 sec0.61.84.3-1.2-1.71.50.91.4-1.7-2.1-1.7-1.6-1.2-0.70.9-1.51.61.4-0.81.61.71.2-0.20.9-0.31.6-0.1
Patch foraging indifference point AUC0.51.22.91.51.5-1.1-1.6-1.71.00.50.71.00.81.1-0.51.3-1.3-0.11.4-0.8-0.4-1.31.60.41.30.0-0.5
Delay disc. indifference point, 0s delay0.50.61.90.40.6-0.7-0.6-0.6-0.20.50.00.60.0-0.3-0.10.9-1.00.31.1-1.0-0.2-0.51.31.01.2-1.4-1.3
Delay disc. indifference point, 16s delay0.00.00.2-0.3-0.20.0-0.00.2-0.20.3-0.2-0.00.0-0.50.1-0.00.0-0.1-0.1-0.2-0.10.2-0.3-0.0-0.1-0.3-0.1
Delay disc. indifference point, 2s delay0.20.30.90.20.4-0.60.0-0.50.00.70.10.50.3-0.1-0.60.4-0.6-0.20.7-0.9-0.5-0.10.20.50.6-0.9-0.8
Delay disc. indifference point, 24s delay0.40.71.9-0.6-0.60.80.40.5-1.0-0.8-1.1-0.6-1.1-1.41.2-0.30.21.3-0.20.51.00.4-0.21.00.3-0.6-1.2
Delay disc. indifference point, 4s delay0.80.83.00.80.9-0.8-1.2-1.10.10.60.00.8-0.2-0.50.21.2-0.80.41.4-0.80.0-0.41.71.41.5-0.5-1.1
Delay disc. indifference point, 8s delay0.30.51.8-0.4-0.40.2-0.00.3-1.2-0.4-1.2-0.6-0.8-0.90.50.3-0.11.00.5-0.20.70.30.61.30.9-0.6-1.2
Indifference point function ln k0.51.52.9-1.5-1.41.51.61.4-1.5-1.3-1.3-1.4-1.7-1.61.2-0.81.01.4-1.21.11.10.9-0.80.5-0.6-0.2-0.6
Indifference point function log k0.51.52.9-1.5-1.41.51.61.4-1.5-1.3-1.3-1.4-1.7-1.61.2-0.81.01.4-1.21.11.10.9-0.80.5-0.6-0.2-0.6
Patch foraging total patch changes 0 sec0.41.23.3-0.9-1.31.20.61.1-1.4-1.8-1.4-1.4-1.0-0.50.7-1.21.21.3-0.61.41.61.0-0.00.8-0.11.4-0.2
Patch foraging total patch changes 12 sec0.30.31.30.90.7-0.4-0.9-0.80.8-0.10.60.60.61.1-0.30.6-0.4-0.20.4-0.1-0.2-0.90.5-0.30.30.20.3
Patch foraging total patch changes 18 sec0.10.31.10.90.6-0.4-1.0-0.80.5-0.20.20.50.50.9-0.50.5-0.50.20.6-0.10.2-0.60.90.20.6-0.1-0.2
Patch foraging total patch changes 24 sec0.30.92.71.30.9-0.8-1.3-1.20.30.00.20.60.70.6-0.31.2-1.10.51.4-0.6-0.1-1.01.60.81.5-0.7-1.1
Patch foraging total patch changes 6 sec0.10.21.20.5-0.10.1-0.2-0.00.2-0.70.2-0.20.61.1-0.4-0.40.1-0.0-0.20.60.3-0.1-0.1-0.6-0.30.40.4
Patch foraging time to switch 0 sec0.00.20.70.2-0.1-0.4-0.00.30.50.80.50.50.50.1-0.30.00.0-0.80.0-0.3-0.60.3-0.4-0.4-0.2-0.20.3
Patch foraging water rate 0 sec0.20.93.40.80.9-0.9-0.6-1.01.10.61.01.01.51.8-1.90.5-0.7-1.00.3-0.7-1.0-1.1-0.0-1.1-0.1-0.20.6
Patch foraging water rate 12 sec0.31.42.9-1.0-1.51.10.80.8-1.7-1.7-1.6-1.3-1.2-1.10.7-1.11.11.7-0.21.01.51.00.61.60.50.3-1.1
Patch foraging water rate 18 sec0.20.31.10.30.4-0.6-0.0-0.50.30.70.60.31.00.6-1.00.3-0.4-0.80.3-0.8-1.0-0.50.0-0.5-0.0-1.00.2
Patch foraging water rate 24 sec0.40.63.70.0-0.40.20.2-0.1-0.7-0.8-0.8-0.2-0.6-0.6-0.10.2-0.31.30.50.00.90.10.81.31.0-1.0-1.9
Patch foraging water rate 6 sec0.10.22.30.1-0.20.00.2-0.1-0.3-0.4-0.30.00.30.1-0.50.1-0.20.40.2-0.20.0-0.40.20.30.4-1.5-0.6
Seeking ratio, delayed vs. immediate footshock0.50.82.7-1.3-0.90.51.51.3-0.00.2-0.2-0.4-0.5-0.7-0.2-1.21.1-0.5-0.9-0.0-0.40.9-1.6-0.4-1.01.10.9
Distance traveled before self-admin0.10.21.00.30.3-0.10.2-0.30.7-0.10.40.10.40.50.50.2-0.3-0.1-0.00.2-0.4-0.80.2-0.5-0.1-1.00.1
Distance traveled after self-admin0.10.20.80.20.4-0.6-0.5-0.60.60.90.40.40.9-0.10.30.4-0.3-0.60.6-0.5-0.9-0.10.30.10.4-0.10.1
Extensor digitorum longus weight3.313.121.84.04.3-4.0-3.7-3.84.64.44.64.44.74.3-4.23.5-3.4-4.22.2-3.5-3.8-3.11.1-3.00.4-0.61.6
Bone: elastic displacement0.60.82.5-1.1-0.81.01.21.2-0.6-0.6-0.6-0.9-0.4-0.50.3-1.00.9-0.0-1.30.80.40.9-1.6-0.7-1.31.10.6
Bone: elastic work0.20.31.7-0.4-0.30.50.70.5-0.1-0.20.0-0.30.10.2-0.4-0.50.4-0.3-0.90.4-0.00.3-1.3-0.9-1.00.70.6
Bone: endosteal estimation2.97.010.63.13.1-3.2-3.0-2.93.13.23.23.22.82.6-3.03.0-3.1-2.42.4-2.9-2.5-2.41.5-1.01.4-0.60.3
Bone: endosteal perimeter1.84.47.62.82.5-2.5-2.7-2.72.11.92.22.51.82.0-2.02.5-2.7-1.02.5-2.0-1.3-2.02.20.12.0-0.8-0.7
Epididymis fat weight0.52.66.52.31.8-1.6-2.0-2.31.00.81.11.40.80.9-0.92.0-2.10.22.2-1.3-0.5-1.42.61.12.3-1.6-1.7
Delta time in closed arm before/after self-admin0.40.41.00.10.2-0.7-0.8-0.30.20.90.40.40.5-0.60.30.3-0.3-0.40.9-0.6-0.30.61.00.80.81.0-0.1
Delta time in open arm before/after self-admin0.50.52.90.50.4-0.50.5-0.20.70.50.40.51.71.2-1.00.3-0.4-1.0-0.1-0.3-1.0-0.6-0.6-1.2-0.5-0.80.4
Diff in mean of infusions in LGA sessions0.50.92.41.21.4-0.6-0.4-1.41.30.21.31.50.41.3-0.71.3-1.4-0.10.4-0.3-0.5-1.50.3-0.70.3-1.0-0.4
Delay discount exponential model param0.30.31.6-0.0-0.10.30.30.20.5-0.20.6-0.20.30.7-0.2-0.60.5-0.5-0.80.6-0.10.0-0.7-1.1-1.00.91.2
Extinction: sum of active levers before priming0.30.41.30.70.2-0.2-1.0-1.00.1-0.40.00.5-0.40.40.10.5-0.50.70.6-0.10.4-0.71.10.60.8-1.1-0.8
Active lever presses in extinction session 61.01.02.9-0.8-0.81.30.81.0-0.4-1.3-0.3-0.8-0.90.21.0-1.31.20.3-1.71.50.70.3-1.2-1.1-1.60.21.1
Bone: final force0.30.61.21.10.9-0.8-1.0-1.10.80.40.80.90.70.9-0.90.8-0.9-0.30.8-0.6-0.4-0.90.6-0.00.7-0.2-0.1
Bone: final moment0.40.61.31.10.9-0.8-1.1-1.10.80.40.80.90.70.9-0.90.8-0.9-0.20.8-0.6-0.4-0.90.70.00.7-0.3-0.2
Food consumed during 24 hour testing period0.30.61.1-0.7-0.90.80.50.7-0.9-1.1-1.0-0.9-0.8-0.61.0-0.90.90.9-0.40.90.90.6-0.10.7-0.00.2-0.3
Glucose4.16.511.03.33.2-2.9-3.2-3.12.92.63.02.92.93.1-2.72.7-2.7-2.32.0-2.3-2.2-2.41.4-1.41.0-1.60.3
Heart weight0.10.10.6-0.10.1-0.10.2-0.20.20.3-0.00.3-0.6-0.70.80.1-0.20.20.3-0.1-0.10.00.20.40.4-0.0-0.2
Delay discount hyperbolic model param0.30.41.8-0.1-0.30.40.40.40.4-0.30.5-0.30.30.7-0.1-0.70.6-0.5-0.90.7-0.10.1-0.8-1.2-1.10.91.3
Intermittent access intake day 1-15 change0.31.43.7-1.2-1.21.51.91.4-1.0-1.4-0.8-1.0-1.3-1.01.5-1.11.20.9-1.41.70.81.0-0.9-0.2-1.01.00.3
Intermittent access intake escalation0.21.33.6-1.2-1.11.51.91.4-1.0-1.3-0.8-0.9-1.2-1.01.5-1.01.30.7-1.41.60.61.0-0.9-0.2-1.11.10.4
Intermittent access intake escalation 20.20.31.1-0.3-0.30.80.90.4-0.4-0.8-0.2-0.3-0.9-0.30.8-0.20.30.7-0.81.00.50.0-0.1-0.3-0.50.2-0.1
Intermitt. access day 1 inactive lever presses0.23.06.3-2.1-1.92.11.61.4-2.1-2.1-2.3-2.0-2.5-2.12.1-1.61.92.0-1.31.61.91.3-0.41.2-0.50.8-0.5
Intermitt. access day 15 inactive lever presses0.21.33.7-0.8-0.91.51.71.0-0.8-1.9-1.0-1.0-1.9-0.81.8-0.60.61.7-1.11.51.3-0.1-0.50.2-0.4-0.7-0.5
Intermitt. access escalation Index0.10.41.5-0.9-0.50.70.60.6-1.1-0.7-0.7-0.7-1.2-0.80.3-0.40.60.7-0.50.20.50.3-0.20.5-0.20.1-0.1
Intermittent access day 1 total infusions0.41.32.8-1.0-1.71.21.01.7-1.7-1.5-1.4-1.3-0.6-1.00.7-1.30.61.4-0.61.01.41.1-0.70.8-0.0-0.0-1.2
Intermittent access day 15 total infusions1.63.88.4-2.1-2.42.52.92.7-2.2-2.6-1.9-2.1-1.6-1.62.0-1.91.91.8-2.12.41.71.6-1.80.1-1.30.7-0.3
Intermittent access terminal intake (last 3 days)1.83.16.5-1.8-2.12.32.62.4-2.2-2.4-2.0-1.9-1.5-1.62.0-1.41.51.9-1.72.11.71.3-1.40.4-0.90.3-0.8
Intermittent access total infusions2.32.85.5-1.7-2.22.02.22.3-2.1-2.2-1.9-1.8-1.1-1.41.5-1.81.41.6-1.51.91.61.6-1.40.4-0.80.5-0.6
Intermittent access day 1 locomotion1.22.25.1-1.7-2.11.61.21.7-2.1-1.9-2.3-1.7-1.0-1.71.4-1.31.31.7-0.71.21.71.4-0.41.30.00.4-1.1
Intermittent access day 15 total locomotion0.31.03.6-0.7-1.01.30.30.7-1.2-1.9-1.3-0.9-1.3-0.71.0-0.60.61.8-0.61.11.50.30.40.70.0-0.2-0.9
Intermittent access total locomotion2.73.37.9-1.8-2.22.21.61.6-2.4-2.8-2.5-1.9-1.8-1.82.1-1.41.52.6-1.22.02.31.2-0.31.3-0.20.2-1.2
Intermittent access standard deviation0.10.51.3-0.4-0.50.81.11.0-0.4-0.9-0.3-0.5-0.10.30.1-0.70.70.1-1.00.90.30.3-1.1-0.8-1.00.40.5
Left kidney weight0.97.415.5-2.7-3.22.62.72.3-3.6-2.9-3.5-2.8-3.2-3.93.4-2.31.93.5-0.82.33.02.90.03.30.71.3-2.5
Right kidney weight1.17.513.1-2.7-3.32.72.72.3-3.6-3.1-3.6-3.0-3.1-3.43.4-2.72.33.2-1.12.63.12.9-0.32.80.21.7-2.0
Cocaine induced anxiety0.00.10.5-0.4-0.20.50.20.4-0.3-0.7-0.2-0.5-0.30.0-0.1-0.40.20.6-0.40.10.3-0.0-0.30.1-0.2-0.3-0.3
Post-drug Anxiety0.80.92.81.01.0-0.6-1.3-1.30.3-0.10.40.4-0.10.3-0.21.0-1.10.81.2-0.70.0-1.11.71.01.4-1.3-1.2
Baseline Anxiety0.30.62.60.60.3-0.7-0.8-0.9-0.00.60.10.5-0.2-0.60.50.6-0.60.31.3-0.6-0.2-0.01.61.31.4-0.1-0.7
Tail length0.84.37.4-2.4-2.32.62.62.0-2.5-2.7-2.6-2.7-2.2-2.02.4-2.22.12.1-2.02.22.01.5-1.30.7-1.10.2-0.3
Length with tail0.31.22.6-0.9-1.11.01.20.5-1.6-1.5-1.6-1.4-1.1-1.31.2-0.80.81.6-0.10.91.20.90.31.50.50.4-1.0
Length without tail0.10.31.00.70.4-0.5-0.3-0.60.2-0.00.20.30.40.4-0.60.6-0.60.30.9-0.20.0-0.20.90.71.00.9-0.6
Times rat made contact with spout7.78.913.4-3.5-3.33.63.63.2-3.4-3.6-3.7-3.6-3.2-3.03.3-3.03.12.8-2.73.33.12.6-1.91.2-1.52.0-0.6
Lifetime Intake1.62.04.5-1.6-1.91.71.92.1-1.7-1.6-1.4-1.6-0.8-1.21.2-1.71.31.0-1.41.51.21.6-1.50.1-1.00.6-0.1
Liver weight, left4.37.511.6-3.4-3.23.12.92.8-3.3-2.9-3.1-3.3-3.4-3.43.2-3.02.72.6-2.22.52.72.8-1.41.6-1.11.6-0.6
Liver weight, right2.23.97.2-2.5-2.52.12.32.7-1.9-1.6-2.1-2.2-1.4-2.01.6-2.52.60.8-2.01.81.52.5-1.60.3-1.62.10.6
Locomotor activity1.82.86.2-1.5-1.41.51.01.0-2.5-1.9-2.5-1.8-2.0-2.32.1-1.11.42.3-0.21.22.11.30.82.40.70.5-1.5
Locomotor testing distance0.51.33.1-1.0-1.31.10.71.1-1.7-1.4-1.7-1.4-0.6-1.11.0-1.21.31.1-0.41.01.41.3-0.01.20.00.8-0.6
Locomotor testing rearing0.10.51.7-0.6-0.60.40.10.3-1.2-0.7-1.1-0.6-0.5-1.00.9-0.20.51.00.30.30.80.60.71.30.70.5-0.9
Locomotion in novel chamber0.10.10.4-0.1-0.30.40.60.4-0.1-0.6-0.4-0.1-0.3-0.20.2-0.10.10.5-0.30.40.4-0.1-0.00.1-0.1-0.5-0.1
Locomotion in novel chamber post-restriction0.10.41.70.00.5-0.3-0.2-0.40.70.80.70.30.80.5-0.50.1-0.1-1.1-0.5-0.4-0.8-0.1-0.7-1.3-0.9-0.10.9
Fecal boli incidents, locomotor time 10.30.83.80.30.0-0.3-0.3-0.5-0.2-0.1-0.50.2-0.6-0.90.80.5-0.91.21.2-0.40.5-0.51.61.71.6-1.3-1.9
Change in fecal boli incidents, locomotor task2.02.14.1-2.0-1.31.91.61.4-1.7-1.6-1.8-1.7-1.9-1.82.0-1.01.81.2-1.61.31.10.8-1.30.4-1.00.60.3
Time >=10cm from walls, locomotor time 10.50.61.9-0.7-0.70.90.50.5-1.0-1.0-0.8-0.9-1.4-0.61.1-0.30.90.9-0.60.91.00.4-0.00.4-0.20.70.3
Bouts of movement, locomotor time 10.10.10.40.10.3-0.2-0.2-0.20.20.20.30.6-0.20.4-0.10.2-0.3-0.20.0-0.3-0.3-0.60.0-0.3-0.1-0.20.4
Total resting periods, locomotor time 10.10.10.50.20.3-0.1-0.3-0.40.30.00.20.6-0.30.30.00.3-0.30.10.1-0.3-0.2-0.70.2-0.10.1-0.40.2
Rest time, locomotor task time 11.52.45.71.61.5-1.5-1.6-1.80.91.00.51.90.40.2-0.42.0-1.90.42.3-1.7-0.8-1.62.21.62.4-2.0-1.5
Distance moved, locomotor task time 10.92.57.1-1.6-1.11.41.61.7-0.7-0.6-0.1-1.7-0.1-0.20.4-1.81.9-0.9-2.41.60.41.7-2.5-2.0-2.72.51.9
Vertical activity count, locomotor time 10.10.72.5-0.5-0.40.40.20.9-0.1-0.10.2-0.70.60.6-0.3-1.01.0-0.9-1.00.80.00.8-1.0-1.2-1.31.61.1
Time >=10cm from walls, locomotor time 20.10.41.70.20.7-0.5-0.4-0.10.50.90.80.30.70.6-0.60.4-0.0-1.1-0.1-0.7-0.9-0.4-0.4-0.9-0.5-0.01.3
Bouts of movement, locomotor time 20.82.55.21.82.0-1.7-1.8-2.10.71.00.81.31.01.2-1.22.3-2.1-0.12.0-1.7-0.7-2.11.90.61.8-2.1-1.4
Total resting periods, locomotor time 20.41.53.31.21.4-1.1-1.4-1.60.10.40.20.80.20.5-0.61.8-1.50.51.6-1.1-0.2-1.71.81.01.7-1.8-1.5
Rest time, locomotor task time 20.50.82.40.2-0.00.1-0.7-0.4-0.3-0.8-0.60.4-1.3-0.60.60.6-0.61.50.8-0.00.8-0.61.61.61.3-0.7-1.4
Distance moved, locomotor task time 21.21.55.7-0.7-0.10.10.70.70.51.01.0-0.51.30.6-0.9-0.70.7-2.0-1.4-0.0-1.10.8-2.2-2.4-2.21.12.2
Vertical activity count, locomotor time 20.40.93.50.30.6-0.9-0.7-0.20.61.41.10.31.81.2-1.40.2-0.0-1.90.0-0.9-1.3-0.1-0.6-1.4-0.70.21.1
Light reinforcement 10.20.72.30.90.8-1.0-1.0-0.90.40.80.20.70.5-0.0-0.21.0-0.8-0.11.4-0.9-0.5-0.51.51.01.4-0.5-0.6
Light reinforcement 22.65.89.22.83.0-2.9-2.5-2.72.62.62.42.92.22.1-2.12.9-2.9-1.52.8-2.5-2.4-2.72.30.02.2-1.4-0.4
Bone: marrow area3.17.611.43.23.3-3.3-3.1-3.13.23.33.33.42.92.7-3.13.2-3.2-2.52.6-3.0-2.6-2.51.6-1.01.6-0.60.2
Bone: maximum diameter1.22.44.62.11.7-1.7-2.0-2.01.41.11.61.71.21.5-1.31.7-2.0-0.41.9-1.3-0.9-1.61.90.31.7-1.2-0.6
Bone: maximum force0.30.51.40.90.9-0.7-0.8-0.90.90.61.00.90.91.1-1.20.6-0.6-0.70.4-0.5-0.6-0.60.2-0.60.10.50.5
Bone: maximum moment0.30.51.30.90.9-0.7-0.9-0.90.80.60.90.80.81.0-1.10.7-0.7-0.50.6-0.6-0.5-0.60.4-0.40.30.40.3
Mean time between licks in bursts0.42.54.1-1.9-1.91.92.02.0-1.6-1.6-1.7-1.8-1.8-1.71.7-1.91.71.2-1.51.61.41.6-1.30.5-1.01.00.1
Mean num. licks in bursts0.41.12.8-0.9-0.91.31.50.9-1.1-1.7-1.3-1.2-1.2-0.61.3-0.80.81.3-0.91.51.20.5-0.50.3-0.40.5-0.4
Cd content in liver0.91.03.00.40.9-0.6-0.1-0.11.31.31.30.81.21.0-1.10.3-0.2-1.7-0.4-0.6-1.2-0.2-1.0-1.7-1.10.51.5
Co content in liver0.40.41.50.70.5-0.7-0.6-0.50.10.50.10.50.4-0.2-0.20.8-0.80.21.1-0.7-0.3-0.31.00.91.2-0.6-1.0
Cu content in liver0.20.30.6-0.6-0.80.60.40.6-0.7-0.7-0.6-0.7-0.2-0.40.1-0.70.70.4-0.50.50.60.7-0.30.1-0.40.5-0.1
Fe content in liver0.20.30.7-0.2-0.50.60.40.7-0.1-0.7-0.2-0.5-0.00.50.1-0.50.6-0.0-0.80.80.20.2-0.7-0.8-0.90.70.6
K content in liver0.30.30.60.50.3-0.7-0.5-0.40.60.70.50.60.60.4-0.30.3-0.3-0.60.6-0.6-0.8-0.30.4-0.00.3-0.50.4
Mg content in liver0.40.41.40.70.5-0.8-0.6-0.60.70.90.70.70.70.5-0.60.5-0.5-0.70.6-0.9-0.8-0.60.3-0.20.3-1.20.3
Mn content in liver0.91.03.71.30.9-1.1-1.2-1.30.60.80.51.00.60.5-0.61.1-1.1-0.21.3-1.1-0.5-0.91.30.61.2-1.9-0.9
Na content in liver3.23.66.52.62.1-2.2-2.2-2.32.11.72.12.22.02.2-2.22.1-2.2-1.31.8-1.7-1.5-2.01.5-0.61.2-1.4-0.1
Rb content in liver0.40.41.0-0.9-1.00.60.60.9-1.0-0.5-0.8-0.9-0.7-0.90.6-0.80.70.6-0.40.40.60.9-0.10.5-0.10.5-0.4
Se content in liver0.81.02.3-1.2-1.11.20.91.1-0.6-0.9-0.8-1.0-0.6-0.40.7-1.31.50.1-1.51.00.60.8-1.2-0.7-1.50.71.1
Sr content in liver0.90.81.6-1.1-1.20.90.80.7-1.1-0.9-1.1-1.0-1.2-1.31.1-0.80.81.1-0.40.70.90.80.20.90.10.2-0.6
Zn content in liver0.00.00.2-0.1-0.20.1-0.10.2-0.0-0.1-0.1-0.10.00.00.2-0.30.4-0.1-0.20.10.10.2-0.2-0.1-0.30.20.4
Bone: minimum diameter3.46.610.93.33.1-2.9-2.8-2.93.02.83.23.13.03.1-3.12.6-2.9-2.42.0-2.4-2.3-2.31.2-1.61.0-1.10.5
Time in familiar zone, hab. session 10.50.52.20.70.2-0.5-0.8-0.70.00.0-0.10.40.2-0.10.50.6-0.70.61.1-0.20.2-0.31.51.21.4-0.7-1.3
Time in novel zone, hab. session 11.21.35.7-0.30.50.00.60.30.90.90.90.20.70.8-1.1-0.30.4-1.8-1.4-0.2-1.00.1-2.1-2.4-2.10.52.2
Total zone transitions, hab. session 10.81.13.4-0.5-0.90.70.50.6-1.4-1.3-1.5-1.0-1.1-1.31.0-0.50.41.70.30.71.50.80.71.91.0-0.1-1.7
Total locomotion distance, hab. session 10.81.12.3-1.0-1.11.10.90.9-1.5-1.3-1.5-1.3-1.3-1.41.1-0.91.01.4-0.40.91.31.00.01.30.20.2-0.9
Locomotion velocity, hab. session 10.91.22.4-1.1-1.21.10.90.9-1.5-1.3-1.5-1.3-1.3-1.51.1-1.01.11.4-0.30.91.31.00.01.40.30.1-0.9
Time in familiar zone, hab. session 21.41.55.91.61.2-1.2-1.2-1.30.90.90.61.30.70.3-0.31.7-1.50.11.6-1.0-0.4-1.21.50.71.6-2.4-1.6
Time in novel zone, hab. session 21.01.12.7-1.4-0.91.01.01.1-0.6-0.5-0.4-1.0-0.5-0.20.0-1.41.3-0.4-1.50.60.11.0-1.5-1.0-1.61.61.6
Total zone transitions, hab. session 21.01.25.30.2-0.40.0-0.4-0.2-0.9-0.6-0.9-0.3-1.0-1.20.90.5-0.51.71.2-0.01.10.01.62.31.9-1.1-2.3
Total locomotion distance, hab. session 21.31.75.0-0.9-1.30.90.60.6-1.7-1.2-1.6-1.1-1.8-2.11.5-0.50.62.00.30.61.50.90.92.21.1-0.4-1.9
Locomotion velocity, hab. session 21.21.65.5-0.9-1.20.80.40.5-1.6-1.1-1.5-1.1-1.7-2.01.5-0.40.51.90.40.51.50.91.02.31.2-0.1-1.8
Novel to familiar place preference ratio0.40.52.4-0.8-0.40.30.50.40.00.30.1-0.40.10.1-0.6-0.80.7-0.9-1.0-0.0-0.40.5-1.1-1.0-1.31.01.5
Novelty place preference0.40.52.6-0.5-0.1-0.00.20.10.40.70.4-0.00.40.3-0.9-0.50.5-1.2-0.7-0.4-0.70.4-1.0-1.2-1.20.91.6
Time in novel zone, NPP test0.40.52.3-0.30.2-0.20.0-0.20.50.90.60.10.50.4-1.0-0.30.2-1.3-0.6-0.5-0.80.1-0.9-1.2-1.10.41.5
Total zone transitions, NPP test0.40.63.70.60.1-0.2-0.5-0.5-0.3-0.4-0.30.1-0.4-0.30.20.7-0.71.10.9-0.30.4-0.61.01.21.2-1.9-1.7
Total locomotion distance, NPP test0.10.20.6-0.5-0.50.30.30.3-0.6-0.3-0.4-0.5-0.8-0.70.4-0.20.30.6-0.00.10.30.30.10.60.2-0.4-0.5
Locomotion velocity, NPP test0.20.30.9-0.7-0.80.50.30.5-0.8-0.5-0.6-0.6-1.0-0.90.6-0.40.50.7-0.00.20.50.40.20.90.3-0.1-0.6
Intraocular pressure0.30.52.1-0.30.00.10.70.40.40.60.2-0.31.00.3-0.5-0.40.4-1.2-0.8-0.2-0.90.1-1.5-1.4-1.20.11.1
Delta distance traveled before/after self-admin0.50.62.10.20.4-0.8-1.1-0.9-0.20.9-0.20.40.2-0.90.10.6-0.50.01.3-1.0-0.30.50.91.41.40.4-0.9
Delta ambulatory time before/after self-admin0.50.93.40.50.5-1.0-1.4-1.1-0.31.0-0.30.40.4-0.9-0.20.6-0.70.11.7-1.1-0.10.61.31.91.80.4-1.1
Parametrial fat weight3.37.714.83.03.1-3.7-3.3-2.93.13.83.03.43.72.6-3.12.4-2.2-3.32.8-3.2-3.2-1.71.8-0.61.5-0.41.1
Pavlov. Cond. lever latency0.00.00.20.10.2-0.2-0.3-0.40.10.30.00.10.10.0-0.2-0.10.0-0.30.1-0.3-0.10.10.3-0.00.0-0.30.2
Pavlov. Cond. magazine entry latency0.50.61.2-1.1-1.10.90.91.1-0.9-0.8-0.8-0.9-1.0-0.80.7-0.80.90.5-0.80.60.60.6-0.80.1-0.60.40.3
Pavlov. Cond. change in total contacts0.10.10.5-0.3-0.20.20.10.1-0.5-0.3-0.2-0.2-0.6-0.50.5-0.1-0.00.60.20.10.20.20.20.70.50.2-0.4
Pavlov. Cond. index score0.10.10.4-0.5-0.50.40.40.7-0.4-0.4-0.3-0.4-0.5-0.30.4-0.30.40.3-0.30.30.20.2-0.40.1-0.20.60.2
Pavlov. Cond. latency score0.20.20.5-0.6-0.60.40.50.7-0.5-0.4-0.4-0.4-0.5-0.40.5-0.30.40.4-0.30.40.30.3-0.40.3-0.10.70.1
Pavlov. Cond. lever contacts0.00.00.20.0-0.10.20.10.3-0.0-0.40.1-0.0-0.10.20.00.1-0.10.3-0.10.30.1-0.2-0.1-0.0-0.00.4-0.1
Pavlov. Cond. magazine entry number0.20.30.80.80.8-0.5-0.7-0.90.40.20.20.50.60.4-0.40.5-0.60.00.7-0.4-0.1-0.40.90.20.7-0.5-0.6
Pavlov. Cond. intertrial magazine entries2.02.56.91.61.8-1.0-0.7-0.92.31.22.41.61.72.4-1.71.3-1.2-1.8-0.2-0.7-1.8-1.8-0.6-2.6-1.0-0.81.4
Pavlov. Cond. lever-magazine prob. diff.0.10.10.3-0.4-0.40.30.30.5-0.2-0.3-0.1-0.2-0.4-0.20.3-0.30.30.2-0.30.30.10.1-0.40.0-0.20.60.2
Pavlov. Cond. response bias0.20.20.6-0.6-0.60.60.60.8-0.4-0.5-0.3-0.5-0.6-0.30.4-0.50.50.3-0.50.50.30.2-0.6-0.1-0.40.30.2
Pavlov. Cond. lever latency1.31.83.9-1.8-1.41.52.01.8-1.2-0.8-1.1-1.5-1.1-1.10.9-1.51.70.2-1.81.20.71.5-1.7-0.5-1.61.10.9
Pavlov. Cond. magazine entry latency0.20.31.50.4-0.00.0-0.3-0.2-0.2-0.5-0.40.0-0.3-0.20.60.3-0.30.80.50.10.4-0.40.90.80.8-1.2-1.0
Pavlov. Cond. change in total contacts0.71.73.61.71.3-1.5-1.9-1.71.01.00.81.41.10.9-0.91.4-1.5-0.21.9-1.3-0.7-1.21.90.81.8-0.9-1.0
Pavlov. Cond. index score0.30.51.21.00.5-0.5-1.0-0.90.3-0.10.20.60.30.5-0.00.7-0.80.40.9-0.20.1-0.81.10.61.0-0.9-0.9
Pavlov. Cond. latency score0.20.41.30.70.2-0.3-0.7-0.70.0-0.3-0.20.3-0.10.10.30.5-0.60.70.8-0.10.3-0.61.10.81.1-1.0-1.1
Pavlov. Cond. lever contacts1.42.04.31.91.5-1.6-2.1-1.91.31.01.21.61.21.3-1.01.6-1.7-0.41.8-1.2-0.8-1.51.70.41.6-1.0-0.9
Pavlov. Cond. magazine entry number0.30.31.0-0.7-0.40.50.70.5-0.2-0.2-0.0-0.4-0.2-0.0-0.2-0.60.7-0.3-0.90.40.10.5-0.9-0.7-1.00.90.9
Pavlov. Cond. intertrial magazine entries0.10.30.70.60.6-0.5-0.3-0.50.70.40.80.50.60.9-0.60.5-0.4-0.60.1-0.3-0.6-0.5-0.1-0.6-0.1-0.30.5
Pavlov. Cond. lever-magazine prob. diff.0.30.51.61.00.4-0.5-1.0-0.80.2-0.20.00.50.20.40.10.7-0.80.61.0-0.20.1-0.71.30.81.2-1.0-1.0
Pavlov. Cond. response bias1.21.73.61.81.3-1.5-1.9-1.71.20.81.11.41.11.2-0.81.4-1.6-0.31.7-1.1-0.7-1.31.70.41.5-0.9-0.8
Time in closed arm before self-admin0.40.61.91.01.0-0.7-1.0-1.00.80.70.51.0-0.30.3-0.61.1-1.0-0.10.8-0.8-0.2-1.01.00.20.7-1.4-0.3
Time in closed arm after self-admin1.41.54.20.91.2-1.6-1.8-1.31.02.11.01.50.6-0.5-0.51.2-1.2-0.81.8-1.8-1.0-0.01.81.11.60.0-0.4
Time in open arm before self-admin0.10.20.9-0.2-0.2-0.0-0.4-0.1-0.4-0.1-0.1-0.2-0.3-0.50.4-0.1-0.00.40.5-0.10.20.20.70.90.70.6-0.3
Time in open arm after self-admin0.30.41.90.70.5-0.30.1-0.40.4-0.00.40.21.11.4-0.90.3-0.5-0.4-0.0-0.0-0.4-0.9-0.3-0.9-0.2-0.80.2
Bone: periosteal estimation1.33.25.52.32.2-2.1-2.2-2.21.91.82.22.11.72.0-2.12.0-2.2-1.31.8-1.7-1.3-1.71.3-0.51.2-0.4-0.0
Bone: periosteal perimeter0.81.63.21.81.4-1.4-1.8-1.81.00.71.21.30.81.3-1.11.3-1.6-0.21.7-0.9-0.4-1.21.70.41.5-0.5-0.7
Bone: post-yield work0.40.71.81.01.1-0.9-1.0-0.91.00.61.10.91.11.3-1.20.7-0.6-0.80.6-0.5-0.6-0.60.6-0.60.21.30.4
Progressive ratio test 1 active lever presses1.52.65.6-1.8-2.31.71.82.4-2.1-1.8-2.0-1.7-1.6-1.91.5-1.81.31.7-0.91.41.51.7-0.61.3-0.10.6-0.8
Progressive ratio test 1 breakpoint1.42.45.2-1.7-2.31.61.82.3-2.0-1.7-1.9-1.6-1.6-1.81.4-1.71.21.7-0.81.31.41.6-0.51.3-0.00.5-0.8
Progressive ratio test 1 inactive lever presses1.64.28.1-2.3-2.42.52.52.9-2.0-2.3-2.1-2.1-2.2-1.92.1-2.32.31.6-2.32.21.91.9-1.80.1-1.61.3-0.0
Progressive ratio test 2 active lever presses3.14.37.1-2.4-2.52.72.52.6-2.2-2.6-2.1-2.3-2.4-1.92.1-2.42.02.0-2.22.32.11.9-1.60.3-1.40.9-0.0
Progressive ratio test 2 breakpoint3.24.06.7-2.3-2.42.62.52.5-2.1-2.5-2.1-2.2-2.3-1.82.0-2.32.01.9-2.22.22.01.8-1.60.2-1.40.90.0
Progressive ratio test 2 inactive lever presses1.44.310.3-1.9-2.12.82.02.1-2.3-3.2-2.2-2.3-2.9-1.92.7-1.61.42.9-2.02.52.71.0-0.80.6-0.8-0.1-1.1
Incentive Sensitization - Responses0.71.84.0-1.3-1.22.01.71.2-1.1-1.9-0.9-1.2-2.0-1.01.5-1.41.11.3-1.91.81.50.9-1.2-0.5-1.40.20.2
Incentive Sensitization - Breakpoint0.92.04.3-1.4-1.22.11.71.2-1.2-2.0-1.0-1.3-2.1-1.01.6-1.31.11.5-2.01.81.60.8-1.2-0.5-1.40.10.1
Sum of active levers in priming session hrs 5-60.20.20.5-0.4-0.40.50.30.3-0.1-0.6-0.0-0.2-0.50.20.6-0.40.70.2-0.60.70.2-0.1-0.2-0.3-0.60.10.6
Progressive ratio0.10.41.20.10.5-0.20.60.30.50.40.60.30.70.9-1.10.2-0.0-0.9-0.4-0.3-0.8-0.5-1.0-1.1-0.70.31.0
Food seeking constrained by brief footshock0.91.23.4-1.3-1.21.10.71.2-0.7-1.0-1.4-1.2-0.9-1.00.6-1.61.50.5-0.80.91.11.6-0.50.6-0.61.90.4
Seeking ratio, punishment vs. effort0.40.81.7-1.0-1.21.00.10.7-0.5-0.8-1.0-0.8-1.1-1.21.1-1.11.10.8-0.70.91.11.30.00.6-0.40.8-0.1
Retroperitoneal fat weight1.77.612.53.43.2-3.5-2.7-2.93.03.53.13.43.22.4-2.92.9-2.9-2.63.0-3.1-3.0-2.11.9-0.41.9-1.30.2
Reaction time number correct0.00.10.20.40.4-0.2-0.3-0.4-0.1-0.20.0-0.00.30.5-0.30.0-0.50.10.3-0.10.2-0.00.20.00.30.2-0.4
Reaction time mean minus median0.10.72.1-0.9-0.51.20.90.8-0.6-1.2-0.7-0.9-1.3-0.81.4-0.10.71.0-1.01.00.7-0.1-0.40.0-0.6-0.4-0.2
Reaction time mean minus median AUC0.00.31.2-0.30.10.70.40.3-0.1-1.0-0.1-0.4-0.9-0.21.10.40.00.9-0.60.80.4-0.7-0.0-0.1-0.2-0.7-0.4
Reaction time num false alarms1.83.15.3-2.2-2.01.91.51.8-2.0-1.6-1.9-2.3-1.7-1.61.7-2.32.20.9-1.61.81.72.1-1.10.4-1.22.30.9
Reaction time num false alarms AUC1.22.84.7-2.1-1.91.71.31.6-2.0-1.5-2.1-2.2-1.6-1.71.7-2.12.21.0-1.21.51.62.1-0.70.9-0.82.20.5
Reaction time trials correct on left0.00.10.20.40.4-0.2-0.3-0.4-0.1-0.20.0-0.00.30.5-0.30.0-0.50.10.3-0.10.2-0.00.20.00.30.2-0.4
Reaction time trials on left0.00.10.30.40.4-0.2-0.3-0.5-0.1-0.10.00.00.40.5-0.40.1-0.50.10.3-0.10.2-0.10.30.00.30.2-0.4
Reaction time mean0.20.51.9-0.70.10.40.80.70.70.30.5-0.0-0.1-0.00.3-0.10.5-0.8-1.10.3-0.6-0.1-1.4-1.3-1.40.51.3
Reaction time mean AUC0.20.51.8-0.7-0.00.60.80.80.5-0.00.3-0.2-0.3-0.00.5-0.20.6-0.5-1.20.5-0.3-0.1-1.3-1.2-1.30.31.1
Median of all reaction times0.50.72.5-0.40.3-0.00.60.61.00.90.90.40.30.3-0.2-0.00.3-1.3-0.9-0.1-1.1-0.1-1.5-1.6-1.40.71.6
Reaction time omissions0.10.10.5-0.30.00.40.50.30.1-0.00.2-0.0-0.1-0.30.50.5-0.0-0.0-0.60.2-0.1-0.3-0.7-0.6-0.6-0.3-0.0
Reaction time false alarm rate2.02.75.1-2.2-2.01.71.51.8-1.9-1.3-1.9-2.1-1.6-1.81.7-2.02.30.8-1.41.51.41.9-0.90.7-0.92.00.7
Reaction time premature initiation rate1.32.05.11.51.7-1.5-1.2-1.71.21.41.21.80.50.8-1.31.9-1.4-0.51.6-1.8-1.4-1.71.30.41.3-2.3-0.6
Reaction time premature initiations0.51.74.21.51.7-1.3-1.2-1.70.90.91.01.50.50.9-1.21.7-1.4-0.31.4-1.5-1.1-1.61.20.41.2-2.0-0.7
Std. dev. reaction times0.30.92.1-1.2-0.61.31.31.2-0.5-1.0-0.6-1.0-1.1-0.81.3-0.41.10.5-1.41.10.50.3-1.2-0.5-1.20.40.3
Reaction time trials completed0.00.10.30.40.4-0.2-0.3-0.5-0.1-0.10.00.00.40.5-0.40.1-0.50.10.3-0.10.2-0.10.30.00.30.2-0.4
Reaction time trials AUC0.10.20.70.70.6-0.5-0.6-0.70.20.20.30.30.70.8-0.70.2-0.7-0.20.4-0.3-0.1-0.20.3-0.20.30.2-0.2
Run reversals in cocaine runway, females0.80.93.4-1.0-0.61.10.60.6-0.8-1.1-0.9-1.0-1.9-1.31.8-0.20.51.4-0.70.81.00.0-0.10.5-0.2-0.5-0.6
Run reversals in cocaine runway, males0.50.52.30.70.5-0.2-1.1-0.9-0.1-0.4-0.2-0.0-0.1-0.10.50.6-0.60.90.90.00.6-0.41.51.01.2-0.5-1.1
Latency to leave start box in cocaine runway0.10.10.40.10.3-0.30.0-0.4-0.00.30.10.20.1-0.30.20.6-0.20.00.4-0.2-0.3-0.10.30.50.50.3-0.5
Latency to leave start box in cocaine runway, F0.10.10.6-0.4-0.00.10.40.1-0.10.3-0.2-0.20.0-0.60.30.00.3-0.3-0.2-0.0-0.30.5-0.40.0-0.20.80.1
Latency to leave start box in cocaine runway, M0.50.51.40.80.4-0.5-0.5-0.70.20.00.40.70.10.20.01.0-0.80.51.0-0.20.0-0.81.10.81.2-0.6-1.1
Std. dev. time between licks in bursts0.30.51.6-0.6-0.81.00.70.7-0.8-1.3-0.4-0.9-0.9-0.40.9-0.70.60.9-0.81.11.00.4-0.50.0-0.5-0.1-0.1
Total sessions with >9 infusions0.70.91.6-1.2-1.21.01.01.2-0.6-0.5-0.4-0.9-0.3-0.80.8-1.31.1-0.1-1.20.90.31.2-1.2-0.6-1.20.90.8
Short access day 1 total inactive lever presses1.32.75.9-2.0-1.62.12.42.0-1.2-1.6-1.3-1.7-1.5-1.01.1-1.72.00.6-2.41.71.01.0-2.2-0.9-2.10.71.2
Short access day 10 total inactive lever presses0.21.05.0-0.5-0.00.71.71.10.5-0.00.3-0.10.10.4-0.3-0.20.5-0.8-1.70.6-0.3-0.2-2.2-2.1-1.9-0.11.3
Short access day 1 total infusions0.81.53.4-1.6-1.31.11.21.8-0.7-0.4-0.7-1.1-0.6-0.80.7-1.81.5-0.4-1.51.00.41.7-1.6-0.7-1.61.51.5
Short access day 10 total infusions0.50.82.7-1.1-1.10.61.41.5-0.4-0.1-0.3-0.60.4-0.4-0.0-1.11.0-0.6-1.10.4-0.21.1-1.7-0.8-1.20.71.0
Short access total infusions0.71.02.9-1.2-1.20.81.31.7-0.7-0.3-0.4-0.8-0.0-0.60.4-1.31.1-0.3-1.20.70.11.4-1.6-0.6-1.21.00.8
Short access day 1 locomotion1.42.35.2-2.3-1.71.81.51.5-1.1-1.0-1.3-1.5-1.2-1.41.5-1.92.10.2-2.11.30.91.4-1.6-0.7-1.91.21.3
Short access day 10 total locomotion0.00.20.70.20.2-0.1-0.2-0.50.20.00.10.70.2-0.30.30.8-0.40.40.5-0.2-0.2-0.40.60.50.6-0.7-0.7
Short access total locomotion0.10.10.7-0.6-0.50.60.30.1-0.3-0.4-0.3-0.2-0.1-0.60.80.00.40.3-0.50.40.20.1-0.2-0.0-0.3-0.2-0.1
One hour access (0.3 mA shock)1.82.24.8-1.4-1.72.02.01.3-1.6-2.2-1.3-1.7-1.7-1.41.7-1.40.71.9-1.51.81.70.9-0.80.2-0.7-0.6-0.8
Compulsive drug intake0.60.91.91.21.2-1.1-1.3-1.41.21.01.11.10.70.6-0.71.1-1.2-0.51.0-1.0-0.6-0.91.0-0.00.7-0.9-0.4
One hour access (shock baseline)1.43.77.5-2.0-2.22.62.72.2-2.1-2.6-1.8-2.2-1.9-1.41.9-2.21.71.8-2.32.41.91.5-1.7-0.2-1.50.60.1
Social response proportion0.70.81.8-1.1-1.00.80.90.8-1.4-1.0-1.3-1.0-1.3-1.21.2-0.31.01.1-0.30.70.60.50.11.10.20.4-0.8
Social responses0.60.82.9-0.4-0.80.30.10.4-1.3-0.7-1.3-0.7-0.6-1.00.8-0.20.71.10.50.40.91.00.81.70.91.1-1.2
Social time0.10.20.90.90.3-0.4-0.3-0.20.00.10.10.10.80.3-0.20.6-0.50.00.60.0-0.1-0.10.60.20.6-0.7-0.9
Soleus weight1.23.67.12.52.1-2.2-2.7-2.21.71.81.72.31.71.7-1.92.3-2.2-0.92.2-1.9-1.2-1.82.10.21.8-1.3-0.8
Bone: stiffness0.00.00.20.20.2-0.1-0.3-0.40.1-0.10.10.1-0.00.2-0.2-0.0-0.00.10.2-0.00.1-0.10.50.20.20.40.2
Tibialis anterior weight6.020.834.74.95.3-5.0-4.6-4.55.95.65.85.55.95.5-5.54.4-4.1-5.52.7-4.4-4.9-3.91.1-3.90.4-0.62.3
Time to tail flick, vehicle, before self-admin2.12.56.3-1.7-1.61.71.42.0-0.9-1.3-1.0-1.0-1.2-0.61.0-2.32.40.0-2.11.81.02.0-1.7-0.8-2.02.51.4
Time to tail flick, vehicle, after self-admin0.51.02.81.01.4-1.0-0.8-1.01.01.11.11.00.40.4-0.51.3-1.5-0.40.8-1.1-1.1-1.40.7-0.20.7-1.7-0.3
Time to tail flick, test, before self-admin0.91.03.8-1.2-1.00.90.81.0-1.1-0.6-1.3-1.0-1.1-2.01.8-0.61.01.0-0.30.50.71.00.21.20.10.6-0.3
Time to tail flick, test, after self-admin0.60.72.7-0.1-0.30.1-0.6-0.3-0.7-0.3-0.9-0.2-0.6-1.41.10.1-0.11.10.70.11.00.71.31.61.20.5-1.2
Delta time to tail flick, vehicle, before/after SA2.02.16.81.61.7-1.4-1.1-1.61.01.21.21.10.90.6-0.82.2-2.4-0.11.6-1.5-1.1-2.01.20.21.5-2.6-1.1
Delta time to tail flick, test, before/after SA0.10.10.30.50.2-0.2-0.3-0.60.1-0.0-0.00.30.50.4-0.40.1-0.40.00.30.00.2-0.10.1-0.00.3-0.1-0.4
Tibia length0.00.10.5-0.4-0.20.30.30.5-0.4-0.2-0.1-0.4-0.4-0.40.1-0.30.10.3-0.20.10.20.3-0.20.2-0.00.70.0
Ambulatory time before self-admin0.20.51.70.60.7-0.20.1-0.51.30.30.90.60.81.10.10.3-0.5-0.7-0.30.1-0.7-1.1-0.2-1.3-0.6-1.00.6
Ambulatory time after self-admin0.40.61.90.70.9-1.0-0.7-1.11.11.20.80.71.40.5-0.30.6-0.7-1.00.8-0.8-1.1-0.40.3-0.20.4-0.50.4
Bone: tissue strength0.40.41.0-0.7-0.70.70.70.5-0.7-0.6-0.8-0.6-0.9-1.00.7-0.50.50.8-0.30.50.60.4-0.30.60.0-0.1-0.3
Total heroin consumption0.80.93.0-0.2-0.70.50.7-0.3-1.1-1.3-1.3-0.5-0.8-0.81.30.00.01.70.50.91.00.21.01.71.2-0.3-1.6
Bone: trabecular number0.10.10.40.30.6-0.5-0.5-0.50.50.60.20.60.40.1-0.30.3-0.2-0.40.4-0.5-0.4-0.20.3-0.00.2-0.00.0
Bone: trabecular spacing2.23.25.9-1.9-2.12.02.11.8-2.3-2.1-2.1-2.1-2.4-2.42.3-1.41.42.3-1.11.61.81.3-0.61.5-0.1-0.1-1.1
Bone: trabecular thickness0.81.12.21.01.2-1.2-1.5-1.11.21.31.21.11.41.3-1.40.7-0.8-1.30.7-1.1-1.1-0.60.5-0.70.20.20.6
Bone: trabecular tissue density0.71.22.8-0.9-1.10.80.30.4-1.5-1.1-1.4-1.0-1.5-1.61.3-0.80.71.50.00.71.41.20.71.70.70.0-1.1
Water consumed over 24 hours0.20.51.4-0.6-0.80.60.40.6-1.0-1.0-1.2-0.8-0.5-0.60.7-0.60.70.9-0.10.70.80.60.20.90.20.3-0.5
Number of responses in last shaping day1.41.84.7-1.7-1.51.51.11.3-1.3-1.2-1.9-1.5-2.0-2.21.8-1.21.41.4-0.91.11.41.3-0.31.1-0.20.9-0.0