Rasgrp2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain isoform ratio XM_039084004.1 0.12 0.08 1.8e-07 0.04 0.06 0.05 0.08 8.9e-05 1.3e-06 1.7e-05 8.5e-08
2 pVTA isoform ratio XM_039084004.1 0.09 0.06 3.0e-03 0.01 0.04 0.02 0.01 1.4e-01 9.3e-03 5.2e-02 7.0e-02
3 Brain gene expression Rasgrp2 0.06 0.04 2.6e-04 0.02 0.04 0.02 0.02 5.3e-03 9.5e-05 1.1e-02 2.7e-03
4 BLA isoform ratio XM_039084004.1 0.12 0.07 3.2e-04 0.04 0.05 0.03 0.04 3.1e-03 9.6e-04 7.9e-03 3.9e-03
5 Eye alternative TSS XM_006230853.3 0.32 0.16 2.2e-03 0.13 0.06 0 0.08 5.8e-03 4.9e-02 3.1e-01 2.7e-02
6 Brain isoform ratio NM_001082977.2 0.06 0.04 7.3e-05 0.03 0.05 0.04 0.04 1.3e-03 4.2e-05 1.3e-04 2.3e-04
7 Liver alternative TSS XM_039083991.1 0.04 0.03 8.5e-03 0.02 0.01 0 0.01 3.9e-03 4.5e-02 8.5e-02 8.2e-03
8 Liver alternative TSS XM_039083991.1 0.04 0.03 7.9e-03 0.02 0.01 0.01 0.02 2.6e-03 1.1e-02 1.3e-02 4.8e-03
9 Liver gene expression Rasgrp2 0.08 0.04 2.4e-04 0.02 0.01 0.03 0.01 2.1e-03 4.2e-02 6.2e-04 1.3e-02
10 PL isoform ratio XM_039084004.1 0.1 0.07 4.2e-05 0.05 0.04 0.04 0.04 5.8e-06 5.5e-05 4.0e-05 1.7e-05
11 Liver isoform ratio NM_001082977.2 0.05 0.03 2.9e-03 0.01 0 0 0 2.8e-02 1.1e-01 1.7e-01 9.3e-02
12 NAcc intron excision ratio chr1_203707570_203708658 0.05 0.03 2.9e-03 0.02 0.01 0.01 0.01 1.9e-03 1.3e-02 1.2e-02 6.7e-03
13 BLA gene expression Rasgrp2 0.08 0.06 7.6e-03 0.03 0.03 0.02 0.02 1.7e-02 1.2e-02 3.6e-02 2.2e-02
14 NAcc isoform ratio XM_006230855.4 0.08 0.06 8.5e-04 0.02 0.01 0.01 0.01 2.7e-03 1.9e-02 2.3e-02 1.7e-02
15 Liver alternative TSS NM_001082977.2 0.04 0.02 4.3e-03 0.01 0.02 0.01 0.01 2.1e-02 3.3e-03 8.0e-03 1.5e-02
16 NAcc isoform ratio XM_039084004.1 0.07 0.04 1.2e-05 0.05 0.04 0.04 0.05 1.3e-06 8.3e-06 1.1e-05 1.2e-06
17 IL isoform ratio XM_039084004.1 0.42 0.17 8.2e-05 0.16 0.1 0.16 0.04 1.2e-04 2.9e-03 1.2e-04 3.3e-02
18 RMTg gene expression Rasgrp2 0.18 0.11 9.3e-03 0.08 0.04 0.05 0.06 4.5e-03 2.7e-02 1.7e-02 1.1e-02
19 Liver alternative TSS NM_001082977.2 0.05 0.03 6.0e-04 0.03 0.03 0.03 0.02 7.9e-04 2.5e-04 6.0e-04 1.1e-03
20 PL gene expression Rasgrp2 0.04 0.03 3.6e-04 0.02 0.03 0.04 0.03 2.5e-03 2.3e-04 5.4e-05 3.3e-04
21 Liver alternative TSS XM_006230853.3 0.1 0.05 1.9e-06 0.04 0.05 0.05 0.05 1.4e-05 1.5e-06 1.4e-06 1.6e-06
22 Adipose isoform ratio XM_039084004.1 0.19 0.08 3.3e-12 0.09 0.09 0.1 0.09 1.0e-09 1.4e-10 6.7e-11 1.6e-10
23 Liver isoform ratio XM_039084004.1 0.21 0.08 8.2e-13 0.09 0.09 0.1 0.1 1.9e-10 7.2e-10 2.4e-11 8.1e-11
24 Liver mRNA stability Rasgrp2 0.04 0.03 2.4e-03 0 0 0 -0 2.1e-01 1.5e-01 2.6e-01 4.0e-01
25 Liver alternative TSS XM_039083985.1 0.11 0.05 5.9e-07 0.04 0.06 0.06 0.06 2.4e-05 5.6e-07 7.5e-07 5.6e-07
26 Adipose gene expression Rasgrp2 0.05 0.03 6.4e-03 0 0.01 0.01 0.01 1.8e-01 1.5e-02 4.2e-02 5.5e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26
Bone: apparent density0.61.03.2-0.10.1-0.2-0.30.60.3-0.9-0.90.90.9-1.1-1.0-1.0-1.11.5-0.21.00.41.60.21.81.11.40.1-1.7-1.7
Area under the delay curve0.30.30.8-0.3-0.2-0.2-0.50.4-0.1-0.9-0.90.60.3-0.20.1-0.2-0.2-0.2-0.90.80.2-0.10.70.60.90.70.6-0.4-0.7
BMI with tail1.85.920.30.81.20.50.02.8-0.5-1.5-1.52.12.1-2.0-2.2-1.5-2.13.3-1.11.31.43.60.54.53.13.71.9-4.4-4.3
BMI without tail0.71.55.81.01.00.70.22.4-0.9-0.6-0.60.80.5-0.7-0.5-0.2-0.81.1-0.30.50.61.31.62.01.61.72.0-1.9-2.2
Body weight0.93.716.02.73.22.52.34.0-2.40.60.6-0.4-0.40.60.31.00.52.51.6-1.6-1.32.4-1.52.30.11.42.4-2.2-1.8
Weight adjusted by age1.11.22.81.61.71.51.71.5-1.11.31.3-1.1-0.80.81.50.90.81.11.4-1.4-0.81.0-1.00.1-0.9-0.50.3-0.00.3
Bone surface1.32.312.31.41.91.21.71.9-0.50.20.20.00.4-0.4-0.5-0.3-0.43.51.7-0.3-0.73.4-1.42.5-0.01.3-0.1-2.2-1.6
Bone volume1.01.79.30.30.70.20.70.80.4-0.3-0.30.61.0-1.0-1.1-1.1-1.03.10.70.60.13.0-0.82.30.51.4-0.8-2.1-1.7
Breakpoint value in progressive ratio session1.41.63.61.81.91.71.91.6-1.31.41.4-1.3-1.11.01.20.91.01.41.8-1.0-1.31.2-1.20.0-0.9-0.60.20.10.3
Number of licking bursts0.10.10.30.40.50.40.50.3-0.30.40.4-0.4-0.40.20.40.10.20.60.2-0.1-0.00.5-0.2-0.0-0.2-0.3-0.20.00.1
Context. condit. distance diff. score1.01.24.0-1.3-1.5-1.5-1.6-0.91.1-1.3-1.31.31.0-0.9-1.1-0.9-0.9-0.9-1.21.20.9-0.72.00.41.00.8-0.1-0.3-0.6
Locomotion velocity, session 10.20.20.9-0.00.20.0-0.20.3-0.4-0.7-0.70.2-0.20.40.10.50.4-0.70.3-0.7-0.6-0.70.30.2-0.30.41.00.1-0.1
Locomotion distance, session 10.40.51.7-0.10.30.0-0.30.7-0.3-1.2-1.20.60.1-0.4-0.1-0.3-0.30.3-0.60.20.50.40.01.21.01.21.2-0.9-1.3
Locomotion velocity, session 20.70.83.01.41.51.31.11.7-1.20.40.4-0.5-0.70.30.90.50.41.00.7-0.7-0.50.9-0.90.70.10.31.2-0.6-0.7
Locomotion distance, session 20.20.31.70.40.60.50.10.9-0.7-0.5-0.50.1-0.40.10.40.20.20.1-0.5-0.10.20.1-0.40.70.80.61.3-0.4-0.8
Locomotion velocity, session 32.02.35.7-1.6-1.1-1.4-1.6-0.61.1-2.4-2.42.01.5-1.5-1.8-1.4-1.40.3-1.20.90.90.51.02.01.52.30.4-1.8-2.0
Locomotion distance, session 30.10.10.4-0.4-0.3-0.4-0.4-0.20.2-0.6-0.60.50.3-0.2-0.3-0.2-0.2-0.2-0.30.10.0-0.10.60.50.20.50.2-0.3-0.4
Stereotopy head waving bouts, day 32.53.06.4-1.9-1.4-1.7-2.0-0.71.3-2.5-2.52.31.9-1.7-2.2-1.5-1.6-0.1-1.81.01.50.31.01.81.92.40.5-1.8-2.1
Stereotopy head waving duration, day 31.31.52.8-1.5-1.3-1.4-1.5-1.11.2-1.7-1.71.51.3-1.3-1.6-1.3-1.2-0.0-1.21.01.20.20.61.11.21.4-0.2-1.1-1.2
Locomotion velocity, session 72.22.44.9-1.5-1.4-1.5-1.7-0.81.4-1.8-1.81.71.5-1.7-1.7-1.8-1.70.5-2.01.81.80.80.71.52.21.7-0.2-1.6-1.9
Locomotion distance, session 70.50.61.7-0.7-0.6-0.6-1.10.00.2-1.2-1.20.90.5-0.7-0.6-0.5-0.6-0.5-1.20.70.5-0.40.40.61.31.00.9-0.6-1.1
Stereotopy head waving bouts, day 70.70.81.4-0.8-0.7-0.8-0.5-0.71.1-0.7-0.70.70.9-0.9-1.1-1.1-0.91.1-0.61.11.11.20.81.00.70.7-1.1-0.9-0.8
Stereotopy head waving duration, day 70.30.42.70.60.70.60.80.7-0.20.40.4-0.3-0.0-0.1-0.2-0.2-0.21.70.50.40.31.6-0.30.90.20.2-0.4-0.7-0.5
Locomotion velocity, session 80.60.72.40.91.10.90.61.4-1.20.10.1-0.3-0.70.80.71.10.8-0.51.0-1.5-1.6-0.5-0.00.0-0.70.21.60.10.1
Locomotion distance, session 81.21.73.3-1.1-0.9-1.2-1.3-0.31.0-1.8-1.81.51.2-1.4-1.2-1.3-1.40.4-1.41.01.30.61.81.71.51.70.2-1.4-1.7
Degree of sensitization distance0.80.81.8-0.7-0.6-0.7-1.00.00.5-1.2-1.21.10.8-1.0-1.0-0.8-1.00.1-1.00.60.80.30.40.91.31.20.5-1.0-1.3
Degree of sensitization stereotypy0.30.32.70.20.40.20.60.20.20.20.2-0.20.2-0.2-0.3-0.4-0.21.60.40.40.31.6-0.20.8-0.00.1-0.9-0.6-0.3
Conditioned locomotion0.70.81.91.21.31.21.11.4-1.10.70.7-0.6-0.80.80.50.90.80.41.1-1.3-1.20.3-1.00.1-0.8-0.10.9-0.10.1
Cocaine response after cond. corrected0.91.02.7-1.4-1.3-1.3-1.6-0.80.8-1.5-1.51.30.8-0.8-1.0-0.6-0.8-1.3-1.20.50.4-1.11.00.30.91.00.5-0.3-0.6
Cocaine response after cond. not corrected0.91.02.4-1.2-1.2-1.2-1.5-0.60.7-1.5-1.51.41.0-0.9-0.9-0.7-0.9-1.1-1.20.50.5-0.81.00.51.01.10.5-0.5-0.8
Cocaine response before conditioning0.30.41.11.00.90.81.00.7-0.50.90.9-0.7-0.20.30.60.30.31.00.5-0.2-0.10.9-0.90.0-0.3-0.4-0.3-0.10.2
Saline control response1.72.36.92.32.32.21.92.6-2.21.31.3-1.3-1.41.31.51.61.30.41.1-1.8-1.10.3-1.6-0.3-0.7-0.51.80.20.2
Bone: connectivity density0.61.03.81.01.20.90.91.6-0.6-0.0-0.00.10.1-0.4-0.1-0.2-0.42.00.90.1-0.42.0-0.71.70.41.00.6-1.5-1.4
Bone: cortical apparent density0.91.22.31.10.91.21.10.7-1.21.31.3-1.3-1.31.41.51.21.4-0.60.5-0.5-0.7-0.8-0.9-1.5-0.6-1.40.41.41.3
Bone: cortical area0.20.41.70.60.80.60.80.5-0.20.50.5-0.20.1-0.0-0.20.0-0.01.30.9-0.5-0.71.2-0.60.7-0.50.2-0.3-0.7-0.2
Bone: cortical porosity0.00.00.20.10.00.20.10.1-0.10.20.20.00.1-0.3-0.3-0.2-0.30.3-0.10.40.00.3-0.00.00.40.10.1-0.3-0.3
Bone: cortical porosity0.20.20.50.70.60.70.60.7-0.60.60.6-0.4-0.30.10.20.30.20.40.4-0.1-0.50.3-0.5-0.20.1-0.20.5-0.2-0.1
Bone: cortical thickness2.74.57.92.72.52.62.42.3-2.52.32.3-2.2-2.12.22.32.42.3-0.32.4-2.2-2.8-0.6-1.8-1.6-2.0-1.71.51.41.6
Bone: cortical thickness1.51.74.51.21.21.20.91.2-1.60.70.7-0.9-1.21.61.41.71.6-1.31.4-1.5-2.1-1.4-1.0-1.2-1.2-0.81.51.21.1
Bone: cortical tissue density1.11.52.71.31.11.31.20.8-1.31.41.4-1.4-1.41.61.61.41.6-0.70.6-0.6-0.8-0.8-1.0-1.6-0.7-1.50.51.51.4
Condit. Reinf. active minus inactive responses0.10.10.20.50.30.40.30.5-0.50.40.4-0.2-0.40.20.40.20.3-0.1-0.40.10.3-0.10.3-0.40.4-0.20.40.2-0.0
Condit. Reinf. active-inactive response ratio0.30.30.90.60.40.60.50.2-0.60.80.8-0.7-0.60.70.60.60.7-0.40.20.0-0.2-0.4-0.1-0.9-0.1-0.80.10.80.7
Condit. Reinf. active responses0.20.20.7-0.1-0.2-0.2-0.2-0.00.2-0.2-0.20.40.2-0.6-0.1-0.5-0.40.5-0.70.60.80.50.60.30.80.4-0.0-0.5-0.6
Condit. Reinf. inactive responses1.11.42.5-0.9-0.9-1.0-1.0-0.51.1-1.2-1.21.31.1-1.6-1.0-1.4-1.41.0-1.11.01.21.20.71.41.21.4-0.5-1.4-1.5
Incentive salience index mean0.20.20.80.30.20.30.10.6-0.3-0.0-0.00.20.0-0.30.1-0.2-0.20.4-0.60.40.60.40.60.40.90.40.6-0.5-0.7
Condit. Reinf. lever presses0.30.41.30.10.1-0.0-0.00.40.2-0.3-0.30.50.5-0.8-0.3-0.6-0.71.1-0.10.20.51.10.41.10.60.90.1-1.1-1.1
Condit. Reinf. active minus inactive responses0.50.61.4-0.8-0.6-0.7-0.4-0.91.0-0.6-0.60.61.0-0.7-0.9-1.0-0.71.0-0.60.81.01.00.50.60.40.5-1.2-0.8-0.5
Condit. Reinf. active-inactive response ratio2.62.74.2-1.7-1.4-1.7-1.1-1.62.1-1.3-1.31.52.0-1.9-1.9-2.1-1.91.7-1.21.41.91.81.11.71.01.4-1.9-1.8-1.4
Condit. Reinf. active responses0.10.10.5-0.00.00.00.1-0.20.2-0.0-0.00.00.3-0.1-0.1-0.3-0.10.7-0.40.50.70.70.20.20.30.1-0.5-0.3-0.2
Condit. Reinf. inactive responses0.50.61.51.10.81.00.71.0-1.20.70.7-0.8-1.01.01.11.01.0-0.60.1-0.2-0.4-0.7-0.2-0.80.0-0.61.00.80.5
Condit. Reinf. lever presses0.60.94.81.01.31.01.41.0-0.40.60.6-0.6-0.10.30.20.10.32.21.2-0.6-0.42.0-1.20.9-0.60.1-0.5-0.8-0.3
Condit. Reinf. lever reinforcers received0.10.10.90.40.40.40.60.1-0.10.30.3-0.4-0.00.30.2-0.00.30.9-0.00.20.40.8-0.30.1-0.0-0.2-0.6-0.10.1
Conditioned reinforcement - actives0.40.42.6-0.7-0.5-0.6-0.1-1.01.1-0.3-0.30.30.6-0.6-0.6-0.7-0.61.00.30.10.51.0-0.30.4-0.30.1-1.6-0.30.1
Conditioned reinforcement - inactives2.42.79.4-2.4-2.5-2.3-1.7-3.12.6-1.1-1.11.21.6-1.5-1.1-1.8-1.40.0-1.11.91.40.11.80.10.40.1-2.90.10.3
Conditioned locomotion3.03.613.7-3.1-3.0-2.8-2.3-3.72.9-1.7-1.71.51.7-1.5-1.7-1.8-1.5-1.0-1.71.61.6-0.81.0-0.40.40.2-2.60.40.5
Patch foraging indifference point 0 sec0.00.00.2-0.1-0.3-0.1-0.1-0.30.20.10.1-0.00.1-0.2-0.3-0.2-0.1-0.00.10.4-0.0-0.00.1-0.20.1-0.2-0.30.10.1
Patch foraging indifference point AUC2.22.56.12.32.22.02.32.2-1.52.12.1-1.5-1.11.31.21.31.21.52.5-1.5-1.91.2-1.0-0.1-1.6-1.00.10.20.7
Delay disc. indifference point, 0s delay0.91.03.4-0.7-0.6-0.8-1.20.20.2-1.8-1.81.40.9-0.7-0.3-0.5-0.6-0.5-1.20.90.7-0.31.40.91.31.51.0-0.8-1.2
Delay disc. indifference point, 16s delay0.70.72.0-1.0-1.0-0.9-0.9-1.01.0-0.7-0.70.70.7-0.7-0.6-0.9-0.80.1-1.41.40.90.20.90.30.90.3-0.9-0.2-0.3
Delay disc. indifference point, 2s delay0.40.51.0-0.6-0.4-0.6-0.6-0.00.5-1.0-1.00.80.6-0.7-0.7-0.6-0.80.3-0.60.60.70.40.60.90.70.90.1-0.7-0.9
Delay disc. indifference point, 24s delay0.40.41.50.50.20.40.00.3-0.70.30.3-0.3-0.50.71.20.70.6-1.2-0.0-0.3-0.5-1.20.5-0.8-0.1-0.40.80.70.6
Delay disc. indifference point, 4s delay0.40.52.2-0.0-0.2-0.2-0.70.6-0.3-0.9-0.90.60.0-0.20.80.1-0.1-0.9-1.10.50.1-0.81.50.20.90.61.3-0.1-0.6
Delay disc. indifference point, 8s delay0.20.21.2-0.2-0.0-0.0-0.40.6-0.4-0.8-0.80.4-0.00.20.10.20.2-0.8-0.40.2-0.4-0.70.40.20.50.61.10.0-0.4
Indifference point function ln k4.36.014.0-3.4-3.5-3.2-3.7-2.92.3-3.0-3.02.62.0-1.9-2.0-1.7-1.9-2.8-3.52.02.4-2.42.50.02.21.50.1-0.2-0.9
Indifference point function log k4.36.014.0-3.4-3.5-3.2-3.7-2.92.3-3.0-3.02.62.0-1.9-2.0-1.7-1.9-2.8-3.52.02.4-2.42.50.02.21.50.1-0.2-0.9
Patch foraging total patch changes 0 sec0.10.10.30.1-0.10.10.0-0.1-0.20.30.3-0.3-0.30.20.10.30.3-0.50.3-0.1-0.4-0.6-0.0-0.6-0.2-0.50.10.50.4
Patch foraging total patch changes 12 sec2.33.07.02.62.52.42.42.6-2.02.12.1-1.8-1.51.41.31.51.41.32.4-1.3-1.81.1-1.5-0.1-1.2-1.00.80.20.5
Patch foraging total patch changes 18 sec0.30.41.11.00.70.70.91.0-0.41.01.0-0.4-0.0-0.10.20.1-0.11.10.7-0.0-0.31.00.00.2-0.1-0.3-0.2-0.3-0.1
Patch foraging total patch changes 24 sec1.82.24.62.12.01.92.01.9-1.71.91.9-1.6-1.41.41.51.51.40.61.9-1.8-1.60.3-0.7-0.5-1.4-1.10.70.60.9
Patch foraging total patch changes 6 sec0.30.41.81.01.00.90.71.3-0.90.40.4-0.4-0.40.50.30.60.40.21.1-0.6-1.00.2-0.20.1-0.2-0.00.9-0.1-0.2
Patch foraging time to switch 0 sec0.81.25.80.50.80.50.51.0-0.1-0.6-0.60.40.6-0.8-0.6-0.8-0.82.4-0.00.80.72.4-0.51.91.01.30.1-1.8-1.7
Patch foraging water rate 0 sec0.91.44.9-1.6-1.9-1.6-1.5-2.21.3-0.2-0.20.30.3-0.2-0.4-0.2-0.1-2.2-0.7-0.00.1-2.11.0-1.5-0.6-0.9-1.01.41.4
Patch foraging water rate 12 sec2.13.315.0-2.5-2.7-2.2-2.5-2.91.4-1.3-1.30.90.2-0.3-0.5-0.1-0.1-3.9-1.50.10.5-3.72.1-2.0-0.2-0.6-0.21.91.4
Patch foraging water rate 18 sec1.11.55.2-1.8-1.9-1.6-2.0-1.61.0-1.5-1.51.20.7-0.8-0.7-0.5-0.6-2.3-1.40.30.8-2.01.2-0.50.60.50.30.40.0
Patch foraging water rate 24 sec1.11.54.7-1.8-2.0-1.7-1.9-1.91.2-1.2-1.21.10.8-0.7-0.9-0.5-0.5-2.2-1.20.20.7-2.01.1-0.60.20.2-0.30.50.5
Patch foraging water rate 6 sec1.11.79.2-1.6-1.9-1.6-1.9-1.70.8-0.9-0.90.80.3-0.3-0.3-0.1-0.2-3.0-1.4-0.20.3-2.81.3-1.30.1-0.20.41.10.7
Seeking ratio, delayed vs. immediate footshock0.20.20.9-0.2-0.3-0.1-0.3-0.30.00.00.0-0.1-0.20.1-0.2-0.20.1-0.4-0.90.90.7-0.3-0.8-0.40.9-0.20.10.3-0.1
Distance traveled before self-admin0.30.31.80.50.70.50.80.2-0.10.40.4-0.4-0.40.10.2-0.10.11.40.7-0.2-0.21.3-0.60.4-0.4-0.1-0.6-0.2-0.1
Distance traveled after self-admin0.30.30.90.40.40.50.7-0.0-0.20.80.8-0.8-0.70.40.40.20.40.60.7-0.1-0.60.5-1.0-0.2-0.7-0.7-0.60.40.5
Extensor digitorum longus weight2.39.227.84.65.14.54.35.3-4.12.52.5-2.2-2.12.32.02.62.22.83.4-3.0-2.82.4-3.21.1-1.4-0.13.0-1.1-0.5
Bone: elastic displacement0.70.85.4-0.3-0.6-0.3-0.6-0.5-0.20.10.1-0.2-0.40.60.50.80.6-2.30.0-0.8-0.7-2.30.2-1.5-0.7-0.80.71.31.2
Bone: elastic work1.11.53.31.31.21.30.81.4-1.60.80.8-0.8-1.01.31.11.61.3-1.31.0-1.6-1.7-1.4-0.7-1.0-1.1-0.61.80.80.8
Bone: endosteal estimation3.57.511.9-2.7-2.2-2.7-2.5-1.62.7-3.0-3.03.23.2-3.2-3.5-3.1-3.21.6-2.42.22.72.02.03.42.63.3-1.1-3.2-3.1
Bone: endosteal perimeter4.38.915.1-3.0-2.5-3.0-2.5-2.23.3-3.1-3.13.33.5-3.5-3.9-3.5-3.52.4-2.12.52.82.71.93.72.43.3-2.1-3.5-3.1
Epididymis fat weight2.55.89.2-3.0-2.9-3.0-2.8-2.52.9-2.7-2.72.72.9-2.6-2.6-2.6-2.70.2-2.22.32.20.52.71.81.92.1-1.7-1.8-1.7
Delta time in closed arm before/after self-admin0.60.63.90.10.10.1-0.50.8-0.8-0.7-0.70.3-0.30.30.60.70.3-1.70.1-0.7-0.5-1.6-0.1-0.50.00.42.00.3-0.2
Delta time in open arm before/after self-admin0.50.51.90.60.50.41.0-0.30.11.21.2-1.0-0.40.30.50.00.31.20.80.0-0.51.00.3-0.1-0.9-1.0-1.40.40.7
Diff in mean of infusions in LGA sessions0.70.82.91.10.91.01.10.8-0.80.90.9-1.0-0.90.81.70.90.90.11.4-0.8-0.9-0.1-0.1-0.7-1.1-0.90.10.70.8
Delay discount exponential model param0.20.20.60.10.10.10.4-0.40.20.70.7-0.4-0.10.1-0.30.10.10.30.7-0.7-0.00.2-0.7-0.4-0.7-0.5-0.60.20.5
Extinction: sum of active levers before priming1.61.64.22.02.01.91.92.1-1.61.41.4-1.2-1.00.91.00.80.91.51.3-0.5-1.01.3-1.10.3-0.3-0.40.7-0.3-0.2
Active lever presses in extinction session 61.81.84.71.81.71.52.01.4-1.01.71.7-1.5-1.10.91.10.90.81.52.2-1.7-1.11.2-1.0-0.1-1.6-1.0-0.30.20.7
Bone: final force0.71.23.61.41.81.41.51.8-1.00.50.5-0.4-0.20.30.10.40.31.91.3-1.0-0.91.8-1.31.3-0.40.60.6-1.2-0.8
Bone: final moment0.71.13.21.31.71.31.41.7-1.00.50.5-0.3-0.20.20.10.40.21.81.3-0.9-0.91.7-1.21.2-0.40.60.6-1.1-0.7
Food consumed during 24 hour testing period0.50.61.50.60.50.50.9-0.1-0.21.01.0-1.0-0.70.70.80.50.70.31.0-0.6-0.60.1-0.7-0.7-1.2-1.1-0.80.81.1
Glucose2.94.36.0-2.4-2.3-2.4-2.4-1.82.3-2.4-2.42.42.2-2.4-2.2-2.4-2.30.4-2.12.22.00.71.11.92.12.1-0.9-1.8-2.0
Heart weight2.02.96.3-2.3-2.4-2.3-2.5-1.91.8-2.2-2.21.91.7-1.6-1.5-1.5-1.6-1.3-2.21.61.6-1.01.20.61.61.2-0.3-0.5-0.9
Delay discount hyperbolic model param0.20.20.60.10.00.10.4-0.50.20.80.8-0.4-0.10.1-0.20.10.10.20.7-0.6-0.00.1-0.7-0.5-0.7-0.6-0.70.30.5
Intermittent access intake day 1-15 change0.30.32.6-0.4-0.5-0.50.0-1.00.80.40.4-0.20.1-0.20.1-0.3-0.20.30.3-0.00.20.20.7-0.4-0.7-0.7-1.60.50.8
Intermittent access intake escalation0.30.32.1-0.5-0.6-0.6-0.1-0.90.90.20.2-0.00.3-0.30.0-0.5-0.40.4-0.00.30.50.30.7-0.2-0.3-0.4-1.50.30.5
Intermittent access intake escalation 20.40.42.00.0-0.1-0.00.5-0.60.40.80.8-0.7-0.30.30.60.10.30.40.6-0.3-0.20.30.0-0.5-1.0-0.9-1.40.71.0
Intermitt. access day 1 inactive lever presses1.21.33.3-1.7-1.7-1.6-1.4-1.81.6-1.2-1.21.11.2-1.0-1.2-1.2-1.0-0.2-0.91.50.8-0.11.10.20.60.5-1.4-0.2-0.2
Intermitt. access day 15 inactive lever presses1.82.05.3-2.0-1.9-1.9-1.4-2.32.2-1.3-1.31.31.7-1.4-1.2-1.7-1.40.5-1.11.51.40.60.90.50.60.6-2.3-0.5-0.2
Intermitt. access escalation Index2.21.95.1-1.7-1.8-1.6-2.0-1.31.1-1.5-1.51.41.0-1.3-1.8-1.1-1.3-1.3-2.31.91.8-1.00.9-0.01.70.80.2-0.2-0.8
Intermittent access day 1 total infusions8.910.315.1-3.8-3.4-3.6-3.4-2.93.5-3.8-3.83.83.9-3.8-3.6-3.5-3.70.7-3.03.43.31.22.32.63.13.2-1.8-2.7-2.7
Intermittent access day 15 total infusions7.48.314.8-3.9-3.6-3.7-3.1-3.63.8-3.1-3.13.13.5-3.3-3.0-3.3-3.30.6-2.42.93.00.92.61.71.92.1-3.0-1.7-1.5
Intermittent access terminal intake (last 3 days)7.58.213.6-3.6-3.1-3.4-2.8-3.13.7-3.1-3.13.23.6-3.4-3.1-3.3-3.41.3-2.12.72.91.62.62.32.02.4-2.9-2.3-1.9
Intermittent access total infusions7.38.112.6-3.4-3.1-3.3-2.8-2.93.5-3.2-3.23.23.5-3.4-3.1-3.3-3.41.1-2.23.02.91.52.12.22.42.5-2.4-2.4-2.1
Intermittent access day 1 locomotion7.17.512.2-3.1-2.8-3.0-3.2-2.02.6-3.5-3.53.43.2-3.2-3.1-2.8-3.20.1-2.92.92.70.52.02.22.92.9-0.6-2.4-2.6
Intermittent access day 15 total locomotion4.44.78.4-2.8-2.7-2.8-2.3-2.72.9-2.2-2.22.32.6-2.5-2.3-2.5-2.40.6-2.02.42.20.81.91.41.61.5-2.4-1.3-1.1
Intermittent access total locomotion9.611.016.5-3.9-3.6-3.8-3.4-3.13.9-3.7-3.73.84.1-4.0-3.6-3.8-4.01.3-3.03.63.31.72.52.73.03.0-2.6-2.8-2.6
Intermittent access standard deviation0.50.52.3-1.1-1.1-1.1-0.7-1.51.3-0.5-0.50.50.7-0.6-0.5-0.8-0.70.1-0.20.50.30.10.8-0.0-0.2-0.0-1.50.10.3
Left kidney weight0.41.22.4-1.4-1.4-1.5-1.2-1.51.6-1.0-1.01.01.2-1.1-1.3-1.3-1.20.3-0.91.21.00.40.30.70.60.6-1.4-0.6-0.5
Right kidney weight0.20.73.3-0.8-0.6-0.8-0.2-1.21.3-0.4-0.40.41.0-0.6-1.3-0.9-0.71.20.30.40.31.1-0.30.9-0.40.3-1.8-0.6-0.1
Cocaine induced anxiety0.10.10.6-0.00.0-0.10.2-0.00.30.00.00.10.2-0.30.1-0.3-0.30.80.3-0.10.60.80.70.5-0.20.1-0.7-0.3-0.1
Post-drug Anxiety0.60.62.00.91.10.91.30.8-0.40.80.8-0.7-0.40.50.50.40.51.41.2-1.3-0.11.3-0.50.5-0.9-0.2-0.5-0.30.2
Baseline Anxiety1.41.52.71.61.61.61.41.5-1.51.11.1-1.2-1.31.31.11.31.30.11.3-1.6-1.5-0.0-1.4-0.3-1.0-0.61.10.40.5
Tail length1.54.77.82.52.32.22.12.3-2.41.91.9-2.3-2.42.52.52.62.4-1.02.6-2.8-2.5-1.3-0.4-1.8-2.5-1.91.61.91.9
Length with tail1.45.19.82.93.12.82.82.8-2.71.91.9-2.2-2.22.42.42.52.30.42.9-3.1-2.80.1-2.0-0.7-2.4-1.21.60.91.2
Length without tail0.71.66.81.41.91.61.71.5-1.30.80.8-0.9-0.71.10.81.11.01.11.4-1.9-1.60.9-2.60.4-1.1-0.10.7-0.40.2
Times rat made contact with spout0.80.92.01.10.91.10.91.1-1.30.90.9-1.0-1.31.11.41.11.1-0.60.4-0.4-0.8-0.7-0.1-1.0-0.4-0.91.01.00.7
Lifetime Intake6.67.511.2-3.3-3.0-3.1-2.9-2.63.2-3.2-3.23.23.4-3.3-3.0-3.1-3.20.8-2.32.92.81.22.02.22.42.6-1.8-2.3-2.2
Liver weight, left0.30.51.2-0.7-0.4-0.7-0.7-0.10.6-1.1-1.10.90.8-0.6-0.9-0.6-0.60.2-0.20.20.10.30.90.90.31.00.0-0.8-0.8
Liver weight, right0.50.83.3-0.7-0.4-0.7-1.00.30.3-1.4-1.41.20.8-0.7-0.8-0.4-0.7-0.4-0.7-0.20.1-0.21.81.20.51.51.0-1.0-1.1
Locomotor activity0.61.06.0-1.2-1.3-1.1-1.4-1.20.5-0.9-0.90.50.1-0.00.00.10.1-2.4-0.6-0.3-0.4-2.31.2-1.1-0.2-0.20.51.00.6
Locomotor testing distance1.01.610.5-1.4-1.5-1.3-1.8-1.10.4-1.2-1.20.70.10.10.10.30.2-3.2-0.8-0.5-0.4-3.01.7-1.3-0.3-0.11.01.20.7
Locomotor testing rearing0.71.16.3-1.3-1.4-1.2-1.6-1.10.5-1.3-1.30.80.2-0.1-0.20.10.1-2.5-0.70.1-0.4-2.31.5-0.8-0.10.20.60.90.5
Locomotion in novel chamber3.44.29.0-2.8-2.7-2.7-2.1-3.03.0-1.9-1.92.02.2-2.3-1.9-2.4-2.20.5-1.61.82.30.72.01.01.11.1-2.7-0.9-0.7
Locomotion in novel chamber post-restriction1.72.14.5-2.0-2.1-2.0-1.8-2.01.9-1.5-1.51.31.5-1.5-2.1-1.5-1.5-0.3-1.41.61.4-0.11.00.20.90.6-1.4-0.4-0.5
Fecal boli incidents, locomotor time 10.50.63.30.10.1-0.20.4-0.30.70.20.20.10.8-0.7-0.8-0.8-0.61.80.50.50.61.70.10.9-0.20.2-1.4-0.9-0.4
Change in fecal boli incidents, locomotor task0.60.52.9-0.2-0.3-0.2-0.80.5-0.3-1.0-1.00.90.5-0.3-0.10.1-0.4-1.2-0.8-0.20.4-1.00.40.21.01.01.7-0.5-0.8
Time >=10cm from walls, locomotor time 14.84.88.9-1.8-1.6-1.9-1.5-1.12.3-1.9-1.92.43.0-2.8-1.7-2.6-2.82.1-1.82.22.62.32.02.52.02.3-1.6-2.8-2.3
Bouts of movement, locomotor time 13.84.28.62.01.72.22.30.8-1.72.92.9-2.8-2.32.12.41.72.30.11.4-1.0-2.0-0.3-2.9-2.2-1.6-2.7-0.22.02.2
Total resting periods, locomotor time 12.62.96.71.71.41.82.00.5-1.32.62.6-2.4-2.01.62.11.31.70.41.0-0.6-1.50.0-2.5-1.7-1.3-2.4-0.51.61.8
Rest time, locomotor task time 10.40.41.3-0.7-1.1-0.9-0.7-1.20.90.10.10.30.5-0.80.1-0.5-0.7-0.6-0.60.20.3-0.51.0-0.6-0.1-0.4-0.80.20.4
Distance moved, locomotor task time 10.40.41.1-0.3-0.0-0.2-0.30.20.1-0.8-0.80.60.4-0.4-0.5-0.5-0.50.5-0.30.60.90.61.01.10.90.90.4-0.8-1.0
Vertical activity count, locomotor time 10.91.02.3-1.5-1.3-1.4-1.4-1.31.1-1.5-1.51.10.9-0.6-1.1-0.8-0.7-0.5-0.80.80.9-0.41.20.50.70.8-0.5-0.2-0.4
Time >=10cm from walls, locomotor time 20.20.21.30.20.10.20.5-0.10.30.50.5-0.30.1-0.10.4-0.3-0.11.10.10.40.11.00.20.1-0.1-0.3-1.1-0.20.1
Bouts of movement, locomotor time 20.91.02.01.11.01.11.10.6-1.01.31.3-1.3-0.91.41.10.91.3-0.00.4-0.1-1.0-0.2-1.4-0.9-0.5-1.10.10.91.0
Total resting periods, locomotor time 20.40.41.10.70.60.80.70.4-0.70.90.9-0.8-0.51.00.80.60.90.00.10.2-0.7-0.1-1.1-0.6-0.2-0.8-0.00.50.7
Rest time, locomotor task time 21.92.14.3-1.9-1.9-1.9-1.9-1.61.8-1.7-1.71.92.1-1.8-1.3-1.5-1.5-0.4-1.41.30.9-0.21.30.61.01.3-0.8-1.0-0.8
Distance moved, locomotor task time 21.01.22.11.41.41.41.41.0-1.21.41.4-1.4-1.51.21.31.11.20.21.3-1.0-0.80.1-0.8-0.6-0.9-1.00.40.80.8
Vertical activity count, locomotor time 20.80.92.40.60.40.50.30.1-0.80.60.6-0.8-1.11.11.11.21.1-1.50.6-1.4-0.8-1.5-0.1-1.3-1.0-1.00.71.31.2
Light reinforcement 10.20.31.20.1-0.10.10.1-0.2-0.10.40.4-0.6-0.60.60.60.50.6-0.80.5-0.2-0.4-0.80.5-1.1-0.7-0.9-0.21.00.9
Light reinforcement 21.01.35.2-1.6-1.3-1.4-0.7-2.01.9-0.8-0.80.61.1-1.1-1.5-1.4-1.11.2-0.50.71.11.2-0.50.50.00.3-2.3-0.6-0.2
Bone: marrow area3.57.611.8-2.7-2.3-2.7-2.6-1.62.7-3.1-3.13.23.2-3.3-3.4-3.1-3.31.5-2.52.32.81.92.13.42.73.3-1.0-3.2-3.2
Bone: maximum diameter0.50.94.5-0.30.1-0.30.3-0.20.9-0.3-0.30.61.1-1.0-1.2-0.9-0.92.10.4-0.10.22.1-0.01.7-0.11.0-1.2-1.6-0.9
Bone: maximum force1.11.99.20.91.50.91.11.7-0.4-0.2-0.20.50.8-0.6-0.9-0.5-0.63.00.7-0.1-0.03.0-1.12.60.61.70.2-2.4-1.9
Bone: maximum moment1.01.77.80.91.40.81.01.6-0.4-0.2-0.20.50.8-0.7-0.8-0.5-0.62.80.6-0.1-0.02.8-1.02.40.61.60.3-2.3-1.8
Mean time between licks in bursts0.91.34.41.21.01.10.61.7-1.60.60.6-0.6-1.01.11.21.51.1-1.50.6-1.4-1.3-1.5-0.6-0.9-0.5-0.42.10.80.5
Mean num. licks in bursts0.10.21.0-0.0-0.20.0-0.20.0-0.30.10.1-0.1-0.30.40.40.40.4-1.0-0.20.1-0.2-1.00.2-0.70.1-0.30.50.60.4
Cd content in liver0.50.62.9-0.9-0.9-1.0-0.4-1.41.2-0.2-0.20.40.8-0.5-0.7-0.7-0.50.30.00.40.40.31.70.2-0.5-0.1-1.70.00.4
Co content in liver1.72.08.40.1-0.30.2-0.2-0.5-0.70.80.8-0.9-1.31.31.21.41.5-2.80.1-0.6-1.0-2.90.7-2.5-1.1-1.70.62.42.1
Cu content in liver0.30.30.90.90.60.80.70.5-0.70.90.9-0.7-0.70.50.70.40.50.20.40.2-0.40.1-0.4-0.5-0.1-0.60.20.40.4
Fe content in liver0.10.10.80.20.30.00.30.20.1-0.0-0.00.10.4-0.4-0.1-0.2-0.20.90.2-0.40.10.90.20.7-0.20.3-0.4-0.6-0.3
K content in liver0.70.72.50.60.70.40.21.3-0.4-0.4-0.40.70.5-0.7-0.5-0.3-0.61.20.00.20.11.30.11.50.91.31.0-1.5-1.6
Mg content in liver1.01.03.0-0.4-0.3-0.4-0.60.20.4-0.9-0.91.11.0-1.1-1.0-1.0-1.00.8-1.21.31.20.90.31.31.71.30.3-1.4-1.5
Mn content in liver0.91.03.11.41.51.31.71.1-0.81.21.2-0.8-0.30.40.50.50.51.81.1-0.8-0.51.6-1.40.4-0.6-0.3-0.3-0.50.1
Na content in liver0.40.52.20.71.00.71.00.8-0.50.50.5-0.4-0.30.20.10.40.31.01.5-0.9-1.10.9-0.60.3-0.90.00.1-0.3-0.0
Rb content in liver1.31.63.0-1.6-1.6-1.6-1.7-1.31.3-1.7-1.71.51.5-1.0-1.5-1.2-1.1-0.5-1.31.71.0-0.30.90.61.41.2-0.3-0.7-0.9
Se content in liver0.60.73.7-0.3-0.3-0.40.2-0.81.00.30.30.00.6-0.9-0.4-1.1-0.81.9-0.20.70.91.8-0.00.80.20.0-1.9-0.8-0.4
Sr content in liver3.53.25.72.12.22.22.41.7-1.82.02.0-2.0-1.91.81.71.81.90.52.3-1.9-2.10.2-1.9-1.1-2.1-1.60.31.21.5
Zn content in liver0.60.61.71.21.11.11.11.0-0.91.01.0-0.9-0.80.70.70.60.70.70.7-0.2-0.60.6-1.3-0.1-0.2-0.50.20.20.2
Bone: minimum diameter2.95.48.6-2.3-2.0-2.2-2.2-1.52.3-2.5-2.52.62.6-2.7-2.9-2.7-2.71.4-2.22.52.21.71.72.72.52.6-1.0-2.6-2.6
Time in familiar zone, hab. session 10.70.61.7-0.6-0.7-0.7-0.8-0.30.7-0.5-0.50.81.1-0.9-1.0-0.8-1.00.1-1.10.91.30.30.90.51.10.7-0.2-0.8-0.8
Time in novel zone, hab. session 10.50.41.8-0.20.00.0-0.2-0.1-0.4-0.4-0.4-0.2-0.60.70.60.70.8-1.30.6-0.8-1.2-1.3-0.1-0.5-0.8-0.20.70.90.7
Total zone transitions, hab. session 10.20.30.70.70.80.80.80.6-0.70.40.4-0.6-0.80.60.70.40.60.50.4-0.2-0.10.40.20.0-0.1-0.20.30.20.1
Total locomotion distance, hab. session 10.81.12.3-1.2-1.0-1.1-1.1-0.81.0-1.4-1.41.10.9-1.2-1.0-1.2-1.10.4-1.11.11.00.51.51.11.11.2-0.3-1.0-1.2
Locomotion velocity, hab. session 10.30.41.4-0.6-0.5-0.5-0.5-0.40.5-0.7-0.70.50.3-0.7-0.4-0.7-0.60.4-0.60.70.60.51.20.70.60.7-0.1-0.6-0.8
Time in familiar zone, hab. session 20.40.52.10.40.20.3-0.10.8-0.80.20.2-0.1-0.40.40.60.80.2-1.40.1-0.8-0.9-1.40.5-0.8-0.3-0.31.40.50.3
Time in novel zone, hab. session 20.10.10.7-0.10.10.00.2-0.30.2-0.1-0.1-0.00.1-0.0-0.2-0.30.10.8-0.10.60.70.8-0.50.60.40.2-0.6-0.3-0.2
Total zone transitions, hab. session 20.50.62.00.40.70.50.21.0-0.5-0.5-0.50.4-0.1-0.3-0.2-0.2-0.31.0-0.70.40.71.1-0.21.31.31.11.1-1.1-1.4
Total locomotion distance, hab. session 21.11.43.5-0.8-0.6-0.7-1.1-0.10.5-1.4-1.41.30.9-1.2-1.1-1.1-1.20.4-1.71.11.40.61.21.41.91.60.7-1.4-1.8
Locomotion velocity, hab. session 21.52.03.9-1.1-0.9-1.1-1.3-0.51.0-1.6-1.61.61.2-1.6-1.4-1.5-1.60.7-1.91.41.70.91.31.72.01.80.2-1.7-2.0
Novel to familiar place preference ratio0.60.74.00.80.90.71.20.6-0.20.80.8-0.6-0.10.10.1-0.10.22.00.50.10.31.8-1.30.7-0.1-0.1-1.0-0.5-0.1
Novelty place preference0.40.42.80.50.60.50.90.30.00.60.6-0.40.00.10.0-0.20.21.70.30.30.31.5-1.10.6-0.0-0.2-1.1-0.4-0.0
Time in novel zone, NPP test0.30.32.00.50.50.40.70.40.00.50.5-0.30.10.0-0.0-0.20.21.40.20.20.31.3-0.90.60.0-0.1-0.9-0.4-0.1
Total zone transitions, NPP test0.50.72.21.21.51.21.11.5-1.10.20.2-0.5-0.70.40.70.50.51.30.9-0.5-0.51.2-0.50.90.10.40.9-0.6-0.7
Total locomotion distance, NPP test0.40.51.4-0.5-0.2-0.4-0.6-0.00.3-1.1-1.10.80.5-0.6-0.5-0.6-0.60.4-0.70.60.50.50.61.11.01.10.5-0.9-1.2
Locomotion velocity, NPP test0.20.30.9-0.4-0.1-0.2-0.3-0.10.2-0.8-0.80.50.2-0.5-0.3-0.5-0.40.5-0.50.60.50.50.40.80.90.80.3-0.7-0.9
Intraocular pressure0.50.74.6-0.3-0.7-0.50.2-1.61.01.01.0-0.50.2-0.20.9-0.4-0.20.30.60.20.10.20.2-0.8-1.0-1.2-2.10.61.2
Delta distance traveled before/after self-admin0.10.10.9-0.0-0.10.0-0.2-0.0-0.30.10.1-0.2-0.30.30.00.40.3-0.90.1-0.3-0.5-0.9-0.0-0.4-0.3-0.30.50.40.3
Delta ambulatory time before/after self-admin0.30.31.30.10.10.2-0.10.1-0.50.00.0-0.3-0.60.50.40.60.6-1.20.2-0.5-0.7-1.10.1-0.5-0.5-0.30.90.60.4
Parametrial fat weight3.46.79.5-2.6-2.7-2.8-2.8-1.82.7-2.7-2.73.03.0-2.9-2.7-2.9-3.00.7-2.73.12.91.03.02.42.72.6-1.2-2.3-2.4
Pavlov. Cond. lever latency0.20.20.7-0.3-0.3-0.2-0.2-0.60.10.00.0-0.2-0.20.50.10.30.4-0.80.3-0.2-0.6-0.8-0.1-0.6-0.6-0.5-0.20.70.8
Pavlov. Cond. magazine entry latency0.30.31.20.20.20.10.10.40.0-0.1-0.10.20.4-0.4-0.3-0.5-0.31.1-0.60.90.91.10.30.81.00.5-0.1-0.8-0.8
Pavlov. Cond. change in total contacts0.40.42.0-0.1-0.0-0.10.2-0.40.50.20.2-0.00.2-0.4-0.2-0.7-0.31.4-0.31.00.91.4-0.40.50.60.1-1.1-0.5-0.4
Pavlov. Cond. index score0.10.10.60.50.40.40.50.3-0.20.50.5-0.3-0.20.00.3-0.00.10.80.00.30.40.7-0.00.10.1-0.2-0.3-0.1-0.1
Pavlov. Cond. latency score0.10.10.40.30.20.20.20.3-0.10.10.10.00.1-0.20.1-0.2-0.20.6-0.40.40.70.60.30.30.50.1-0.1-0.4-0.4
Pavlov. Cond. lever contacts0.10.10.30.1-0.0-0.0-0.10.3-0.0-0.2-0.20.30.2-0.4-0.1-0.2-0.20.2-0.40.30.50.30.50.30.50.40.3-0.4-0.5
Pavlov. Cond. magazine entry number0.30.41.0-0.7-0.7-0.7-1.0-0.20.3-1.0-1.00.80.5-0.5-0.5-0.3-0.6-0.9-0.60.00.1-0.80.60.30.50.70.7-0.3-0.5
Pavlov. Cond. intertrial magazine entries0.30.31.2-0.3-0.6-0.3-0.1-1.00.50.70.7-0.5-0.3-0.00.2-0.1-0.0-0.3-0.10.30.0-0.4-0.2-1.0-0.4-1.0-1.10.90.9
Pavlov. Cond. lever-magazine prob. diff.0.20.20.90.60.60.60.70.5-0.30.60.6-0.4-0.20.10.30.00.20.90.10.20.30.9-0.20.20.1-0.2-0.2-0.2-0.1
Pavlov. Cond. response bias0.10.10.40.40.40.40.60.1-0.20.50.5-0.4-0.30.20.20.10.30.60.30.20.10.5-0.2-0.1-0.1-0.4-0.40.10.2
Pavlov. Cond. lever latency0.30.42.5-0.2-0.5-0.2-0.5-0.3-0.20.10.1-0.0-0.40.30.30.40.3-1.6-0.50.2-0.1-1.50.5-1.10.2-0.50.61.00.6
Pavlov. Cond. magazine entry latency1.41.63.81.92.01.81.91.9-1.51.41.4-1.3-1.10.91.10.90.91.31.5-0.7-1.21.2-1.20.3-0.6-0.50.6-0.10.0
Pavlov. Cond. change in total contacts0.81.17.20.91.21.01.50.5-0.20.90.9-0.8-0.10.20.2-0.20.22.71.10.1-0.12.5-1.51.0-0.4-0.2-1.3-0.8-0.2
Pavlov. Cond. index score0.81.04.81.21.51.21.51.1-0.60.90.9-0.8-0.30.30.40.10.32.21.2-0.4-0.52.0-1.40.9-0.5-0.1-0.4-0.8-0.3
Pavlov. Cond. latency score0.60.84.50.91.20.91.20.9-0.40.60.6-0.5-0.10.00.2-0.10.02.11.0-0.2-0.32.0-1.01.1-0.20.2-0.4-0.9-0.6
Pavlov. Cond. lever contacts0.30.41.60.60.70.50.90.4-0.10.50.5-0.5-0.20.20.30.10.21.21.1-0.7-0.51.1-1.00.4-0.9-0.2-0.6-0.30.1
Pavlov. Cond. magazine entry number2.53.07.4-2.5-2.7-2.5-2.7-2.21.9-2.0-2.01.81.5-1.4-1.4-1.2-1.4-2.2-2.01.11.4-1.92.2-0.41.00.8-0.30.1-0.3
Pavlov. Cond. intertrial magazine entries0.60.72.0-1.1-1.2-1.2-1.1-1.11.1-0.8-0.80.90.9-0.9-0.8-0.9-0.9-0.4-0.90.70.9-0.31.40.00.50.4-0.6-0.3-0.3
Pavlov. Cond. lever-magazine prob. diff.1.01.24.51.51.71.41.71.4-0.91.11.1-1.0-0.50.50.60.40.52.11.3-0.5-0.71.9-1.50.8-0.5-0.2-0.2-0.6-0.2
Pavlov. Cond. response bias0.81.03.01.31.51.21.61.0-0.71.11.1-1.0-0.60.60.60.40.61.71.5-0.8-0.91.6-1.50.5-1.0-0.4-0.4-0.30.1
Time in closed arm before self-admin0.30.31.6-0.10.0-0.10.2-0.30.50.20.20.10.4-0.5-0.4-0.6-0.51.3-0.00.40.41.20.70.90.20.2-0.9-0.7-0.4
Time in closed arm after self-admin0.30.30.5-0.5-0.5-0.4-0.7-0.20.1-0.7-0.70.70.3-0.50.0-0.3-0.5-0.6-0.70.30.7-0.50.50.20.70.60.7-0.3-0.6
Time in open arm before self-admin0.80.96.3-0.2-0.4-0.1-0.90.3-0.7-0.7-0.70.3-0.40.70.10.80.7-2.5-0.6-0.1-0.0-2.4-0.4-1.30.5-0.01.81.00.4
Time in open arm after self-admin0.70.82.00.50.20.40.4-0.1-0.50.90.9-1.0-1.01.00.40.81.1-1.00.6-0.4-0.9-1.1-0.7-1.4-1.0-1.3-0.01.41.3
Bone: periosteal estimation1.53.07.2-1.3-0.9-1.3-1.0-0.71.6-1.6-1.61.82.1-2.1-2.4-2.0-2.02.1-0.81.01.32.20.82.71.22.2-1.0-2.5-2.1
Bone: periosteal perimeter0.81.33.9-0.7-0.3-0.7-0.3-0.31.0-0.9-0.91.01.3-1.3-1.6-1.3-1.31.9-0.20.50.61.90.22.00.61.4-0.9-1.8-1.4
Bone: post-yield work6.08.218.7-1.6-1.0-1.6-1.2-0.62.2-2.3-2.32.63.0-3.1-3.1-3.3-3.14.1-2.23.03.24.30.44.23.33.4-1.6-4.1-3.8
Progressive ratio test 1 active lever presses1.81.94.9-2.1-2.0-1.9-1.7-2.22.0-1.5-1.51.31.5-1.4-1.4-1.5-1.4-0.1-0.81.40.90.01.10.30.60.7-1.6-0.4-0.4
Progressive ratio test 1 breakpoint1.41.54.4-1.9-1.8-1.8-1.5-2.11.8-1.3-1.31.11.3-1.2-1.4-1.3-1.2-0.2-0.61.20.8-0.11.10.30.40.5-1.5-0.3-0.2
Progressive ratio test 1 inactive lever presses0.50.61.5-1.2-1.2-1.1-1.1-1.20.9-0.8-0.80.70.6-0.6-0.6-0.7-0.6-0.7-0.51.10.4-0.60.80.00.50.3-0.40.1-0.1
Progressive ratio test 2 active lever presses3.84.08.2-2.8-2.6-2.6-2.1-2.82.9-2.0-2.02.02.4-2.2-1.9-2.4-2.20.6-1.42.11.90.81.81.01.21.2-2.5-1.0-0.8
Progressive ratio test 2 breakpoint3.23.69.5-2.8-2.7-2.7-2.2-3.12.8-1.8-1.81.82.1-2.0-1.7-2.1-2.0-0.0-1.41.91.80.11.60.30.90.7-2.5-0.5-0.3
Progressive ratio test 2 inactive lever presses6.17.115.0-3.6-3.5-3.5-2.9-3.93.7-2.5-2.52.63.0-2.8-2.7-3.0-2.80.3-2.43.13.10.62.41.11.81.4-3.2-1.1-0.9
Incentive Sensitization - Responses0.80.81.8-1.0-1.0-1.0-0.7-1.11.3-0.7-0.70.81.1-1.1-0.7-1.1-1.10.8-0.51.01.00.80.80.60.60.5-1.4-0.6-0.5
Incentive Sensitization - Breakpoint0.91.02.3-1.2-1.1-1.2-0.8-1.31.4-0.7-0.70.91.2-1.2-0.8-1.2-1.10.7-0.71.11.00.80.90.60.60.5-1.5-0.6-0.4
Sum of active levers in priming session hrs 5-62.22.14.61.51.41.32.10.4-0.42.12.1-1.8-1.10.91.70.70.81.72.1-1.5-1.11.4-1.3-0.5-2.1-1.6-1.50.61.3
Progressive ratio0.91.04.30.81.00.70.61.3-0.4-0.1-0.10.20.3-0.60.0-0.5-0.62.1-0.20.60.92.1-0.11.71.11.10.5-1.7-1.7
Food seeking constrained by brief footshock0.30.41.60.60.50.50.20.8-0.90.00.0-0.4-0.70.61.20.80.7-0.90.2-0.6-0.4-0.90.0-0.4-0.2-0.21.20.50.2
Seeking ratio, punishment vs. effort1.01.27.6-0.6-0.9-0.5-0.8-0.8-0.1-0.1-0.1-0.1-0.50.70.40.80.7-2.8-0.3-0.5-0.8-2.70.2-1.8-0.6-0.90.61.81.4
Retroperitoneal fat weight4.213.924.6-5.0-4.9-4.9-4.7-4.54.6-4.1-4.14.14.2-3.9-4.3-4.0-3.8-0.5-4.13.83.80.03.31.93.12.8-2.5-2.0-2.2
Reaction time number correct0.40.62.20.90.80.80.80.7-0.70.70.7-0.6-0.60.61.00.80.7-0.21.1-1.5-1.0-0.3-0.8-0.5-0.9-0.50.50.30.6
Reaction time mean minus median1.01.35.91.51.81.51.91.3-0.81.11.1-0.8-0.20.70.50.40.62.40.7-0.5-0.02.2-1.30.9-0.3-0.0-0.4-0.8-0.2
Reaction time mean minus median AUC0.70.92.61.31.51.31.61.0-0.81.21.2-0.9-0.40.80.80.60.71.50.8-0.8-0.31.3-0.80.2-0.7-0.4-0.2-0.20.3
Reaction time num false alarms0.40.64.5-0.1-0.4-0.1-0.70.2-0.5-0.3-0.30.2-0.30.30.40.60.4-2.1-0.6-0.2-0.1-2.0-0.1-1.20.3-0.21.50.80.3
Reaction time num false alarms AUC0.50.73.30.60.20.5-0.10.9-1.00.20.2-0.3-0.70.70.91.00.8-1.8-0.2-0.5-0.4-1.8-0.5-1.20.1-0.41.70.80.4
Reaction time trials correct on left0.40.62.20.90.80.80.80.7-0.70.70.7-0.6-0.60.61.00.80.7-0.21.1-1.5-1.0-0.3-0.8-0.5-0.9-0.50.50.30.6
Reaction time trials on left0.50.72.61.00.90.90.90.8-0.80.80.8-0.7-0.70.71.10.90.8-0.11.2-1.6-1.1-0.3-1.0-0.6-1.0-0.50.50.40.6
Reaction time mean0.10.21.3-0.10.20.10.5-0.50.30.20.2-0.20.10.2-0.1-0.20.31.1-0.20.50.41.0-0.50.30.0-0.1-1.1-0.10.2
Reaction time mean AUC0.20.21.5-0.20.1-0.00.4-0.60.40.10.1-0.10.20.1-0.2-0.40.11.2-0.30.70.61.1-0.30.40.20.0-1.2-0.20.1
Median of all reaction times0.20.21.3-0.6-0.3-0.3-0.0-0.90.6-0.2-0.20.10.2-0.0-0.4-0.50.10.7-0.40.70.50.7-0.20.40.20.1-1.1-0.10.1
Reaction time omissions0.60.94.91.01.21.31.30.7-1.00.90.9-0.9-0.81.20.80.81.20.60.6-0.8-0.60.5-2.2-0.2-0.4-0.50.20.30.5
Reaction time false alarm rate0.30.42.7-0.2-0.5-0.3-0.80.2-0.3-0.5-0.50.3-0.10.00.00.30.1-1.6-0.90.30.3-1.50.3-0.70.60.11.20.4-0.1
Reaction time premature initiation rate2.43.16.72.12.22.21.62.6-2.51.21.2-1.3-1.82.11.62.32.0-1.11.5-2.2-2.3-1.2-1.4-1.0-1.2-0.72.61.00.8
Reaction time premature initiations4.15.89.92.92.92.92.43.0-3.22.02.0-2.1-2.52.82.53.02.7-1.12.4-3.1-3.0-1.3-2.1-1.5-2.0-1.42.71.51.5
Std. dev. reaction times0.40.52.30.71.00.91.30.3-0.30.80.8-0.7-0.20.60.30.20.61.50.2-0.10.21.3-1.30.2-0.2-0.3-0.8-0.20.3
Reaction time trials completed0.50.72.61.00.90.90.90.8-0.80.80.8-0.7-0.70.71.10.90.8-0.11.2-1.6-1.1-0.3-1.0-0.6-1.0-0.50.50.40.6
Reaction time trials AUC0.30.42.00.80.70.70.60.7-0.70.60.6-0.4-0.50.50.80.70.6-0.31.0-1.4-0.9-0.4-0.7-0.5-0.8-0.30.60.30.5
Run reversals in cocaine runway, females0.90.94.10.00.10.0-0.71.1-0.5-1.2-1.21.00.5-0.7-0.8-0.2-0.7-0.5-1.10.60.8-0.2-0.20.91.61.42.0-1.1-1.6
Run reversals in cocaine runway, males0.30.32.3-0.2-0.1-0.3-0.1-0.40.1-0.2-0.2-0.00.00.40.00.40.4-0.80.7-0.9-0.8-0.81.5-0.4-1.0-0.2-0.00.50.6
Latency to leave start box in cocaine runway0.80.92.4-0.8-0.6-0.7-0.7-0.20.7-1.1-1.11.01.0-0.9-1.6-1.0-0.90.7-0.91.21.10.80.40.91.21.1-0.2-1.0-1.2
Latency to leave start box in cocaine runway, F0.10.10.7-0.1-0.1-0.1-0.00.10.2-0.1-0.10.00.1-0.2-0.6-0.4-0.10.5-0.50.90.30.5-0.30.10.50.1-0.3-0.1-0.3
Latency to leave start box in cocaine runway, M0.80.81.8-0.8-0.6-0.8-0.8-0.20.7-1.3-1.31.11.0-0.9-1.3-0.8-0.90.4-0.20.30.90.50.91.10.71.30.1-1.2-1.1
Std. dev. time between licks in bursts0.40.53.40.1-0.00.1-0.40.6-0.7-0.2-0.20.1-0.30.50.40.80.5-1.9-0.1-0.8-0.7-1.80.0-0.7-0.1-0.01.50.60.4
Total sessions with >9 infusions3.64.07.5-2.5-2.1-2.3-2.4-1.62.0-2.7-2.72.52.3-2.3-2.3-2.0-2.3-0.1-1.81.81.70.21.61.52.02.2-0.3-1.7-1.9
Short access day 1 total inactive lever presses2.73.06.3-2.5-2.5-2.3-2.4-2.42.1-2.1-2.11.91.8-1.7-1.4-1.8-1.7-0.8-2.02.01.8-0.50.80.31.51.1-1.1-0.5-0.8
Short access day 10 total inactive lever presses1.31.53.9-1.6-1.9-1.6-1.9-1.71.1-1.2-1.21.10.8-0.7-0.8-0.7-0.7-2.0-1.61.31.0-1.81.1-0.70.80.2-0.10.50.1
Short access day 1 total infusions4.54.87.2-2.7-2.5-2.4-2.5-2.02.3-2.6-2.62.52.3-2.5-2.6-2.4-2.50.1-2.62.72.50.41.11.42.42.0-0.8-1.6-1.9
Short access day 10 total infusions6.26.910.6-2.7-2.3-2.5-2.6-1.62.5-3.3-3.33.23.1-3.1-2.8-2.9-3.11.1-2.42.92.81.41.42.52.93.0-0.8-2.7-2.8
Short access total infusions4.04.57.7-2.4-2.0-2.2-2.3-1.42.0-2.8-2.82.72.5-2.5-2.4-2.2-2.50.4-1.92.22.20.71.21.92.32.4-0.4-2.1-2.2
Short access day 1 locomotion4.24.56.8-2.4-2.2-2.3-2.5-1.52.0-2.6-2.62.62.3-2.4-2.5-2.1-2.4-0.1-2.62.32.40.31.31.62.42.2-0.4-1.7-1.9
Short access day 10 total locomotion2.73.04.7-1.9-1.9-1.9-2.0-1.31.7-2.0-2.02.01.8-2.2-1.9-1.9-2.20.1-2.12.21.80.41.11.22.11.6-0.5-1.3-1.7
Short access total locomotion3.13.25.5-2.0-1.8-1.9-2.1-1.21.6-2.3-2.32.21.9-2.0-2.3-1.8-2.0-0.0-2.02.01.70.30.71.42.11.9-0.2-1.5-1.8
One hour access (0.3 mA shock)6.37.315.2-3.8-3.8-3.7-3.2-3.93.7-2.8-2.82.93.1-3.0-2.6-2.9-3.0-0.3-2.32.62.60.02.80.91.51.5-2.8-1.0-0.9
Compulsive drug intake5.15.28.12.62.22.51.92.3-2.82.42.4-2.4-2.82.72.52.72.7-1.61.9-2.2-2.6-1.8-1.5-2.0-1.8-2.02.42.01.7
One hour access (shock baseline)7.68.818.0-4.0-3.7-3.8-2.9-4.24.2-2.9-2.92.93.5-3.3-3.0-3.5-3.31.0-2.33.03.01.32.41.61.61.7-3.9-1.6-1.1
Social response proportion0.30.40.90.81.00.81.00.9-0.60.60.6-0.6-0.70.40.30.40.41.00.6-0.4-0.40.9-0.60.2-0.4-0.20.0-0.00.0
Social responses0.50.61.01.00.80.80.80.8-0.80.90.9-0.9-1.00.71.00.80.7-0.10.8-0.9-0.8-0.20.4-0.6-0.8-0.70.40.60.6
Social time0.50.61.70.90.90.90.80.8-0.90.70.7-0.7-0.90.80.80.90.8-0.31.3-1.2-1.1-0.3-0.4-0.3-0.9-0.50.70.50.5
Soleus weight2.05.713.0-3.5-3.6-3.4-3.4-3.33.0-2.5-2.52.42.2-2.3-2.3-2.3-2.3-1.5-2.72.32.5-1.12.80.21.71.2-1.4-0.5-0.8
Bone: stiffness0.81.38.00.91.30.91.21.3-0.30.10.10.00.4-0.4-0.5-0.5-0.42.80.80.10.02.8-1.01.90.41.0-0.2-1.8-1.4
Tibialis anterior weight4.515.537.55.76.15.55.65.8-4.83.93.9-3.6-3.33.33.23.73.22.85.0-4.7-4.12.3-3.90.2-3.3-1.42.7-0.00.8
Time to tail flick, vehicle, before self-admin0.60.62.30.10.4-0.00.10.80.1-0.7-0.70.60.6-0.6-0.6-0.5-0.61.3-0.60.11.01.40.31.50.91.10.1-1.2-1.2
Time to tail flick, vehicle, after self-admin0.70.74.30.91.00.70.32.1-1.1-0.2-0.20.3-0.0-0.1-0.20.3-0.20.40.1-0.4-0.00.40.81.30.71.01.9-1.0-1.3
Time to tail flick, test, before self-admin2.42.34.1-1.4-1.3-1.4-1.8-0.61.0-2.0-2.02.01.7-1.6-1.5-1.3-1.7-0.3-1.81.41.9-0.01.51.52.01.90.5-1.5-1.7
Time to tail flick, test, after self-admin0.10.10.20.20.30.20.20.1-0.20.20.2-0.4-0.30.3-0.20.20.3-0.00.1-0.5-0.1-0.0-0.40.1-0.3-0.20.10.20.1
Delta time to tail flick, vehicle, before/after SA0.20.21.60.60.60.60.21.1-0.80.20.2-0.1-0.30.20.20.50.2-0.30.5-0.3-0.7-0.20.30.20.00.21.3-0.2-0.4
Delta time to tail flick, test, before/after SA4.43.97.01.81.81.82.20.8-1.52.42.4-2.6-2.42.21.41.92.30.12.2-2.1-2.2-0.3-2.5-1.7-2.6-2.4-0.32.02.2
Tibia length0.61.78.41.31.51.12.00.6-0.11.41.4-1.0-0.30.20.50.10.22.92.0-1.0-0.72.6-1.30.9-1.6-0.4-1.6-0.70.2
Ambulatory time before self-admin0.40.43.00.30.40.30.8-0.10.30.50.5-0.30.1-0.2-0.1-0.4-0.31.70.50.10.01.6-0.30.6-0.3-0.1-1.2-0.5-0.1
Ambulatory time after self-admin0.30.41.6-0.6-0.5-0.5-0.2-0.90.8-0.1-0.10.10.2-0.6-0.6-0.8-0.61.0-0.21.00.51.0-0.10.50.20.0-1.3-0.3-0.3
Bone: tissue strength0.10.10.5-0.1-0.1-0.00.1-0.30.30.20.2-0.10.2-0.2-0.1-0.3-0.20.7-0.30.20.70.6-0.60.10.2-0.1-0.6-0.2-0.1
Total heroin consumption3.13.67.42.72.72.72.62.5-2.32.22.2-2.1-1.91.81.91.71.81.12.1-1.7-1.80.8-2.4-0.2-1.3-1.21.10.40.7
Bone: trabecular number0.60.94.3-0.00.2-0.10.20.30.5-0.4-0.40.50.7-1.0-0.9-1.0-0.92.10.20.80.42.1-0.21.70.71.0-0.6-1.5-1.3
Bone: trabecular spacing0.40.52.70.2-0.20.2-0.20.0-0.50.40.4-0.3-0.50.50.70.70.5-1.6-0.3-0.3-0.2-1.60.2-1.30.0-0.70.81.00.7
Bone: trabecular thickness0.91.01.9-1.2-1.1-1.2-1.1-1.01.2-1.1-1.11.01.0-1.1-1.1-1.3-1.10.5-0.91.40.80.60.50.90.90.9-0.8-0.8-0.9
Bone: trabecular tissue density1.21.75.2-1.9-2.1-1.9-1.7-2.31.8-1.0-1.01.01.1-1.1-1.0-1.2-1.0-0.8-1.51.21.4-0.71.5-0.40.50.1-1.50.20.1
Water consumed over 24 hours1.82.13.31.61.51.71.61.1-1.61.61.6-1.7-1.71.71.81.61.8-0.51.3-1.1-1.4-0.7-1.1-1.5-1.2-1.60.61.51.5
Number of responses in last shaping day0.40.41.7-0.9-1.0-0.8-0.9-1.10.5-0.5-0.50.30.2-0.1-0.1-0.1-0.0-1.3-0.40.30.4-1.20.4-0.5-0.0-0.1-0.10.60.4