Cd72

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression Cd72 0.04 0.04 7.9e-03 0.03 0.02 0.03 0.02 1.0e-02 3.0e-02 1.1e-02 2.0e-02
2 Liver gene expression Cd72 0.02 0.02 8.4e-03 0.01 0.01 0 0.01 3.8e-02 3.1e-02 1.3e-01 5.4e-02
3 NAcc gene expression Cd72 0.05 0.03 5.2e-08 0.05 0.07 0.06 0.06 2.8e-06 2.3e-08 8.1e-08 2.5e-07
4 PL gene expression Cd72 0.04 0.03 2.0e-05 0.05 0.04 0.04 0.04 7.2e-06 7.4e-05 6.5e-05 5.8e-05
5 Adipose gene expression Cd72 0.04 0.07 1.4e-03 0.03 0.02 0.03 0.02 3.7e-04 2.8e-03 3.6e-04 1.7e-03
6 Adipose isoform ratio NM_001015016.1 0.08 0.05 2.7e-11 0.1 0.09 0.09 0.09 7.4e-11 9.7e-10 6.0e-10 9.2e-10
7 Adipose isoform ratio XR_005504445.1 0.15 0.08 0.0e+00 0.21 0.21 0.22 0.22 8.2e-23 2.7e-23 9.5e-24 5.8e-24
8 Adipose mRNA stability Cd72 0.02 0.02 7.2e-03 0.02 0.02 0.01 0.02 2.1e-03 4.7e-03 4.7e-02 3.7e-03
9 IL gene expression Cd72 0.16 0.1 4.3e-04 0.17 0.16 0.16 0.16 8.7e-05 1.1e-04 9.5e-05 1.3e-04
10 LHb gene expression Cd72 0.23 0.15 5.4e-03 0 0.02 0.03 0.01 3.1e-01 1.1e-01 7.5e-02 1.6e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density1.42.32.8-1.31.61.7-1.61.5-1.4-1.6-1.6-1.6-1.4
Area under the delay curve0.60.61.10.6-0.8-0.81.0-0.50.80.80.90.71.0
BMI with tail3.09.712.6-2.73.13.3-3.22.9-2.9-3.3-3.5-3.4-2.6
BMI without tail5.411.215.0-3.93.83.7-3.53.3-3.3-3.5-3.4-3.2-1.2
Body weight3.414.217.9-4.24.24.2-3.83.8-3.7-3.9-3.9-3.6-1.7
Weight adjusted by age0.20.21.0-0.90.30.30.30.0-0.1-0.00.00.11.0
Bone surface0.61.01.4-1.21.21.2-1.00.9-0.9-1.0-1.1-1.1-0.3
Bone volume0.61.11.5-1.01.21.2-1.10.9-1.0-1.1-1.1-1.1-0.7
Breakpoint value in progressive ratio session0.80.92.90.1-0.7-0.71.3-1.00.90.90.80.81.7
Number of licking bursts4.45.27.3-2.32.52.5-2.72.4-2.3-2.2-2.0-2.0-1.5
Context. condit. distance diff. score0.10.10.20.4-0.3-0.20.3-0.20.20.20.10.1-0.4
Locomotion velocity, session 10.80.86.2-1.20.30.10.4-0.40.40.30.10.12.5
Locomotion distance, session 10.20.31.8-0.90.40.30.00.00.0-0.1-0.1-0.11.4
Locomotion velocity, session 23.23.74.8-1.71.91.9-1.82.0-2.2-2.2-2.1-2.1-1.4
Locomotion distance, session 21.21.63.8-1.91.61.3-1.41.3-1.3-1.0-0.7-0.70.9
Locomotion velocity, session 30.20.21.6-0.4-0.0-0.10.3-0.30.40.30.30.31.3
Locomotion distance, session 32.02.13.3-1.81.71.7-1.31.2-1.2-1.5-1.7-1.7-0.2
Stereotopy head waving bouts, day 31.01.13.70.1-0.6-0.70.8-0.80.61.11.41.51.9
Stereotopy head waving duration, day 31.01.22.30.5-0.8-0.90.9-0.90.71.21.51.51.4
Locomotion velocity, session 70.00.00.10.3-0.3-0.20.2-0.20.30.20.10.10.0
Locomotion distance, session 70.20.20.3-0.50.50.5-0.40.3-0.5-0.5-0.5-0.5-0.0
Stereotopy head waving bouts, day 71.82.13.0-1.71.71.7-1.51.4-1.3-1.4-1.4-1.4-0.2
Stereotopy head waving duration, day 70.30.40.9-0.90.80.7-0.70.6-0.5-0.4-0.3-0.30.4
Locomotion velocity, session 80.40.52.6-0.3-0.1-0.40.2-0.30.30.60.80.81.6
Locomotion distance, session 80.10.21.0-0.70.30.2-0.10.1-0.20.00.20.21.0
Degree of sensitization distance1.21.21.91.2-1.2-1.31.0-1.00.71.11.41.40.4
Degree of sensitization stereotypy1.31.52.0-1.21.31.4-1.21.1-0.9-1.2-1.4-1.4-0.5
Conditioned locomotion0.20.21.20.1-0.3-0.20.6-0.60.50.3-0.0-0.01.1
Cocaine response after cond. corrected2.83.14.01.2-1.6-1.71.9-2.01.91.91.71.71.9
Cocaine response after cond. not corrected2.93.35.51.0-1.5-1.61.7-1.81.81.92.02.02.4
Cocaine response before conditioning0.60.71.3-1.01.00.9-1.11.1-0.9-0.7-0.3-0.3-0.2
Saline control response0.30.41.1-1.10.90.7-0.70.4-0.4-0.2-0.0-0.00.9
Bone: connectivity density1.01.62.3-0.91.11.3-1.11.2-1.1-1.4-1.5-1.5-1.4
Bone: cortical apparent density0.30.32.20.6-0.10.0-0.40.2-0.3-0.4-0.4-0.4-1.5
Bone: cortical area2.43.74.8-1.62.02.0-2.22.0-1.9-2.0-1.9-1.9-1.5
Bone: cortical porosity0.40.50.60.7-0.7-0.70.7-0.60.70.70.70.70.3
Bone: cortical porosity0.00.00.0-0.00.00.00.10.00.10.0-0.0-0.00.0
Bone: cortical thickness1.32.13.5-0.71.31.4-1.61.3-1.2-1.5-1.7-1.7-1.9
Bone: cortical thickness0.10.10.40.7-0.3-0.3-0.0-0.30.30.1-0.0-0.1-0.2
Bone: cortical tissue density0.20.31.80.7-0.2-0.1-0.30.1-0.2-0.2-0.3-0.3-1.3
Condit. Reinf. active minus inactive responses0.60.60.9-0.80.80.8-0.91.0-0.9-0.8-0.7-0.7-0.5
Condit. Reinf. active-inactive response ratio0.50.51.01.0-0.8-0.80.5-0.70.80.70.60.60.1
Condit. Reinf. active responses3.13.85.1-2.02.12.0-2.12.2-2.2-2.0-1.7-1.7-1.1
Condit. Reinf. inactive responses3.84.56.8-2.22.32.2-2.32.5-2.6-2.2-1.7-1.7-1.4
Incentive salience index mean4.25.17.0-2.62.52.4-2.32.5-2.4-2.3-2.1-2.0-0.9
Condit. Reinf. lever presses9.112.119.7-4.44.03.8-3.43.8-3.7-3.5-3.1-3.0-0.9
Condit. Reinf. active minus inactive responses0.81.01.1-1.01.01.1-1.01.0-0.9-1.0-0.9-0.9-1.0
Condit. Reinf. active-inactive response ratio0.40.41.0-0.30.50.5-0.40.5-0.5-0.6-0.7-0.7-1.0
Condit. Reinf. active responses2.23.04.0-2.02.01.9-1.92.0-1.8-1.7-1.5-1.5-1.1
Condit. Reinf. inactive responses3.03.75.1-2.02.12.0-2.22.2-2.0-1.9-1.6-1.6-1.3
Condit. Reinf. lever presses3.04.15.4-1.82.02.0-2.12.2-2.3-2.1-1.8-1.8-1.9
Condit. Reinf. lever reinforcers received2.63.74.7-2.22.12.1-2.02.1-2.0-1.9-1.7-1.6-1.2
Conditioned reinforcement - actives0.50.51.2-0.50.50.6-0.20.4-0.5-0.8-1.0-1.1-1.0
Conditioned reinforcement - inactives0.00.00.10.2-0.3-0.20.3-0.30.20.1-0.1-0.1-0.1
Conditioned locomotion0.70.82.3-0.70.70.9-0.30.4-0.4-1.0-1.4-1.5-1.1
Patch foraging indifference point 0 sec0.30.41.6-1.20.50.60.4-0.1-0.0-0.2-0.5-0.31.3
Patch foraging indifference point AUC7.89.013.0-3.63.43.3-3.03.2-3.2-3.1-2.6-2.9-1.1
Delay disc. indifference point, 0s delay1.71.82.31.1-1.3-1.41.5-1.31.41.41.41.41.3
Delay disc. indifference point, 16s delay1.81.83.00.8-1.2-1.21.5-1.31.71.41.31.11.7
Delay disc. indifference point, 2s delay0.10.10.40.10.20.2-0.20.4-0.2-0.3-0.2-0.3-0.6
Delay disc. indifference point, 24s delay0.20.20.50.5-0.4-0.50.3-0.30.30.40.70.50.4
Delay disc. indifference point, 4s delay0.10.10.10.4-0.3-0.30.3-0.10.30.20.20.00.2
Delay disc. indifference point, 8s delay0.00.00.2-0.10.10.1-0.10.5-0.3-0.20.1-0.00.2
Indifference point function ln k2.73.84.72.2-2.1-2.12.0-2.02.02.01.82.01.1
Indifference point function log k2.73.84.72.2-2.1-2.12.0-2.02.02.01.82.01.1
Patch foraging total patch changes 0 sec0.40.72.4-1.50.91.0-0.00.2-0.4-0.7-0.9-0.80.8
Patch foraging total patch changes 12 sec2.53.24.5-1.92.02.1-1.61.6-1.6-1.9-1.9-2.0-1.1
Patch foraging total patch changes 18 sec0.60.71.6-1.31.01.0-0.80.8-0.9-0.9-0.7-0.5-0.1
Patch foraging total patch changes 24 sec2.42.95.1-2.31.92.0-1.31.5-1.5-1.7-1.9-1.9-0.4
Patch foraging total patch changes 6 sec2.43.66.9-2.62.12.2-1.31.7-1.7-2.0-2.1-2.00.0
Patch foraging time to switch 0 sec2.64.07.32.7-2.3-2.31.7-1.91.72.02.02.10.2
Patch foraging water rate 0 sec1.72.74.5-2.11.81.9-1.21.1-1.0-1.6-2.1-2.1-0.2
Patch foraging water rate 12 sec0.00.10.4-0.20.10.10.0-0.20.10.20.00.20.7
Patch foraging water rate 18 sec0.60.91.8-0.60.81.0-0.70.7-0.4-0.9-1.3-1.3-1.1
Patch foraging water rate 24 sec0.30.51.70.20.20.4-0.40.2-0.1-0.7-1.1-0.9-1.3
Patch foraging water rate 6 sec0.40.60.9-1.00.90.9-0.90.5-0.2-0.6-0.9-0.8-0.0
Seeking ratio, delayed vs. immediate footshock4.85.67.3-2.12.32.4-2.02.7-2.4-2.5-2.7-2.6-1.6
Distance traveled before self-admin3.03.26.7-2.62.22.1-1.81.7-1.8-1.6-1.6-1.30.2
Distance traveled after self-admin0.50.61.1-0.60.80.7-1.11.1-1.0-0.8-0.5-0.5-0.4
Extensor digitorum longus weight4.417.323.8-4.94.64.6-4.34.3-4.2-4.2-4.0-4.0-1.5
Bone: elastic displacement3.13.67.12.7-2.3-2.12.0-2.02.11.81.41.3-0.2
Bone: elastic work1.01.34.22.1-1.3-1.00.7-0.81.00.60.20.1-1.7
Bone: endosteal estimation0.61.22.7-1.61.41.3-1.21.1-1.2-0.9-0.6-0.60.6
Bone: endosteal perimeter0.61.33.1-1.81.41.3-1.01.1-1.2-1.0-0.7-0.70.8
Epididymis fat weight0.30.81.9-1.41.10.9-1.31.0-0.9-0.6-0.3-0.30.4
Delta time in closed arm before/after self-admin3.53.45.1-1.41.81.8-1.92.3-2.0-1.9-1.8-1.7-1.8
Delta time in open arm before/after self-admin0.70.71.10.5-0.8-0.80.8-0.60.80.91.00.81.0
Diff in mean of infusions in LGA sessions0.00.00.10.2-0.2-0.2-0.2-0.10.20.10.00.1-0.1
Delay discount exponential model param0.50.50.9-0.50.70.7-0.80.5-0.7-0.7-0.8-0.5-0.9
Extinction: sum of active levers before priming1.91.92.51.6-1.5-1.61.5-1.11.21.41.41.51.0
Active lever presses in extinction session 60.30.30.80.5-0.6-0.50.9-0.50.60.40.10.10.4
Bone: final force0.91.52.6-1.41.51.3-1.61.3-1.2-1.1-0.9-0.9-0.6
Bone: final moment0.71.12.2-1.11.31.1-1.51.2-1.0-1.0-0.8-0.8-0.6
Food consumed during 24 hour testing period0.50.61.0-1.01.00.9-1.00.8-0.7-0.7-0.6-0.60.3
Glucose1.11.62.3-1.51.41.4-1.31.3-1.2-1.2-1.2-1.4-0.4
Heart weight0.50.81.1-1.01.00.9-0.91.0-1.0-0.8-0.7-0.80.1
Delay discount hyperbolic model param0.40.40.8-0.50.60.6-0.80.4-0.6-0.6-0.7-0.5-0.9
Intermittent access intake day 1-15 change1.21.22.4-0.50.90.9-1.21.2-1.1-1.0-1.0-1.1-1.5
Intermittent access intake escalation1.71.62.3-0.81.21.2-1.41.3-1.3-1.2-1.2-1.3-1.5
Intermittent access intake escalation 22.32.34.6-0.71.21.3-1.71.4-1.4-1.5-1.6-1.7-2.1
Intermitt. access day 1 inactive lever presses0.80.91.1-0.90.91.0-1.00.9-0.9-1.0-1.0-1.1-0.6
Intermitt. access day 15 inactive lever presses0.00.00.3-0.20.10.10.2-0.0-0.00.00.10.10.6
Intermitt. access escalation Index0.50.41.7-1.30.90.8-0.70.5-0.4-0.2-0.1-0.10.4
Intermittent access day 1 total infusions0.40.41.50.3-0.7-0.51.2-0.80.90.50.1-0.00.7
Intermittent access day 15 total infusions0.80.92.0-0.70.81.0-0.60.8-0.8-1.0-1.3-1.4-1.0
Intermittent access terminal intake (last 3 days)1.11.22.7-0.90.91.1-0.70.8-0.8-1.1-1.5-1.6-1.1
Intermittent access total infusions1.11.33.0-1.01.01.2-0.60.8-0.8-1.2-1.6-1.7-0.9
Intermittent access day 1 locomotion0.60.62.10.6-0.9-0.71.5-1.01.10.5-0.0-0.10.3
Intermittent access day 15 total locomotion0.40.51.30.9-0.8-0.61.1-0.70.90.4-0.2-0.4-0.2
Intermittent access total locomotion0.40.40.90.8-0.5-0.20.8-0.40.5-0.2-0.8-0.9-1.0
Intermittent access standard deviation0.60.60.9-0.40.70.7-0.80.8-0.9-0.8-0.7-0.9-0.8
Left kidney weight0.30.81.6-1.31.11.1-0.80.9-0.8-0.8-0.8-0.80.5
Right kidney weight0.00.10.7-0.40.1-0.10.10.1-0.00.10.10.10.8
Cocaine induced anxiety1.51.82.51.2-1.3-1.31.2-1.61.51.51.51.20.8
Post-drug Anxiety0.20.30.6-0.80.40.2-0.60.2-0.30.20.60.50.7
Baseline Anxiety2.02.13.5-1.31.51.4-1.61.9-1.7-1.5-1.4-1.0-1.0
Tail length1.95.910.7-3.32.92.6-2.62.5-2.5-2.4-2.0-1.80.2
Length with tail0.51.84.6-2.11.71.6-1.31.4-1.3-1.0-0.6-0.60.8
Length without tail0.40.91.30.9-1.0-0.91.1-0.91.01.11.10.90.6
Times rat made contact with spout0.50.61.4-0.30.70.8-0.90.7-0.7-0.7-0.8-0.8-1.2
Lifetime Intake0.70.82.1-1.20.81.0-0.20.5-0.5-0.9-1.3-1.5-0.2
Liver weight, left0.30.41.1-0.80.70.5-1.00.8-0.7-0.10.50.50.5
Liver weight, right0.30.61.50.2-0.4-0.50.4-0.40.60.91.11.21.1
Locomotor activity0.00.00.1-0.10.10.0-0.10.30.0-0.1-0.1-0.10.1
Locomotor testing distance0.30.51.7-0.2-0.3-0.40.5-0.40.80.80.80.81.3
Locomotor testing rearing0.30.51.6-1.30.90.8-0.80.8-0.3-0.3-0.2-0.10.3
Locomotion in novel chamber0.20.31.60.20.10.2-0.20.4-0.3-0.5-0.7-0.6-1.3
Locomotion in novel chamber post-restriction2.53.04.7-0.91.61.6-1.91.8-1.9-1.9-1.8-1.6-2.2
Fecal boli incidents, locomotor time 10.30.41.01.0-0.8-0.70.7-0.40.40.50.40.5-0.1
Change in fecal boli incidents, locomotor task0.50.51.8-1.30.90.9-0.60.0-0.1-0.5-0.7-0.50.2
Time >=10cm from walls, locomotor time 10.20.21.0-0.4-0.1-0.10.3-0.50.50.50.40.41.0
Bouts of movement, locomotor time 11.71.82.71.6-1.5-1.51.4-1.41.21.21.21.40.8
Total resting periods, locomotor time 11.82.03.71.9-1.6-1.71.4-1.41.21.21.31.50.4
Rest time, locomotor task time 10.80.93.41.9-1.1-1.10.5-0.50.30.40.50.8-1.2
Distance moved, locomotor task time 11.01.13.7-1.91.31.3-0.90.6-0.4-0.7-0.7-1.00.7
Vertical activity count, locomotor time 10.60.62.4-1.60.80.6-0.40.10.20.20.40.21.4
Time >=10cm from walls, locomotor time 20.10.10.2-0.40.30.2-0.20.4-0.5-0.20.10.20.4
Bouts of movement, locomotor time 20.60.71.0-0.90.80.8-0.71.0-0.8-0.9-1.0-0.9-0.1
Total resting periods, locomotor time 20.30.40.7-0.50.50.5-0.40.7-0.6-0.7-0.8-0.8-0.1
Rest time, locomotor task time 20.70.81.51.1-1.0-0.91.0-1.21.00.80.70.7-0.0
Distance moved, locomotor task time 20.50.61.1-0.40.70.7-1.11.0-0.9-0.7-0.4-0.5-0.7
Vertical activity count, locomotor time 20.20.30.6-0.60.70.5-0.80.7-0.5-0.20.20.30.3
Light reinforcement 10.61.26.5-1.70.80.5-0.40.00.10.40.70.72.6
Light reinforcement 21.31.79.4-1.20.1-0.20.7-0.80.81.11.41.33.1
Bone: marrow area0.71.42.8-1.71.51.4-1.31.2-1.3-1.1-0.7-0.70.4
Bone: maximum diameter2.03.74.8-2.12.22.1-2.22.1-2.2-2.0-1.6-1.6-0.7
Bone: maximum force2.54.46.2-2.22.42.2-2.52.3-2.2-2.1-1.9-1.8-1.2
Bone: maximum moment2.03.55.1-1.82.11.9-2.32.0-1.9-1.9-1.7-1.6-1.2
Mean time between licks in bursts0.71.02.00.8-0.9-1.10.6-0.70.81.11.41.40.8
Mean num. licks in bursts1.82.23.41.8-1.8-1.71.7-1.61.41.41.21.20.5
Cd content in liver0.90.91.3-0.50.90.9-1.20.9-1.1-1.0-0.9-0.9-1.2
Co content in liver2.12.53.61.3-1.4-1.41.4-1.81.51.81.91.91.4
Cu content in liver1.01.22.41.6-1.2-1.20.6-1.00.91.21.31.20.2
Fe content in liver0.60.83.8-0.7-0.1-0.30.5-0.60.50.81.00.91.9
K content in liver0.60.61.00.4-0.6-0.70.8-0.90.80.80.90.91.0
Mg content in liver0.60.61.10.6-0.7-0.71.0-0.80.70.80.80.80.4
Mn content in liver0.40.41.1-0.30.50.5-0.60.7-0.8-0.7-0.5-0.6-1.0
Na content in liver2.22.43.81.4-1.4-1.61.1-1.41.41.71.91.91.1
Rb content in liver4.86.07.72.7-2.5-2.52.4-2.72.82.62.42.51.2
Se content in liver2.12.64.3-1.71.61.4-1.82.0-2.1-1.7-1.3-1.4-1.0
Sr content in liver0.70.61.2-1.10.80.7-0.61.1-1.1-0.7-0.4-0.4-0.4
Zn content in liver0.40.41.20.10.40.4-0.50.5-0.5-0.7-0.8-0.8-1.1
Bone: minimum diameter0.00.00.10.2-0.1-0.00.1-0.0-0.1-0.2-0.2-0.2-0.3
Time in familiar zone, hab. session 10.90.95.61.0-0.20.1-0.20.2-0.4-0.6-0.8-0.9-2.4
Time in novel zone, hab. session 14.94.810.80.8-1.6-1.91.9-1.82.02.42.62.63.3
Total zone transitions, hab. session 10.00.00.0-0.10.10.0-0.10.1-0.2-0.2-0.1-0.10.1
Total locomotion distance, hab. session 10.81.11.9-0.60.80.8-1.11.2-1.4-1.2-0.9-0.9-1.4
Locomotion velocity, hab. session 12.13.04.5-1.51.71.6-1.82.0-2.1-1.9-1.6-1.6-1.5
Time in familiar zone, hab. session 20.40.41.11.1-0.7-0.60.2-0.30.30.30.40.4-1.0
Time in novel zone, hab. session 22.42.44.40.9-1.3-1.41.7-1.71.81.61.41.32.1
Total zone transitions, hab. session 20.30.41.1-1.00.80.6-0.50.5-0.6-0.6-0.5-0.50.5
Total locomotion distance, hab. session 20.81.11.5-1.11.11.1-1.01.1-1.2-1.2-1.1-1.1-0.5
Locomotion velocity, hab. session 21.21.62.1-1.31.31.3-1.21.3-1.5-1.4-1.3-1.3-0.7
Novel to familiar place preference ratio4.64.85.91.7-2.1-2.12.4-2.32.42.32.12.12.2
Novelty place preference5.85.97.32.1-2.4-2.42.7-2.62.72.62.32.32.1
Time in novel zone, NPP test7.27.48.82.3-2.7-2.73.0-2.82.92.92.72.62.4
Total zone transitions, NPP test0.40.51.6-1.30.90.7-0.60.6-0.5-0.5-0.4-0.40.8
Total locomotion distance, NPP test1.41.93.8-1.91.61.6-1.21.4-1.4-1.4-1.2-1.20.1
Locomotion velocity, NPP test2.13.04.8-2.22.01.9-1.61.7-1.8-1.8-1.7-1.7-0.3
Intraocular pressure1.72.34.6-2.21.91.8-1.31.3-1.5-1.5-1.4-1.4-0.0
Delta distance traveled before/after self-admin0.70.81.31.0-0.9-1.00.6-0.60.80.91.11.10.2
Delta ambulatory time before/after self-admin1.71.92.71.7-1.5-1.61.0-1.11.31.41.61.60.5
Parametrial fat weight0.10.20.4-0.60.50.4-0.60.1-0.1-0.1-0.0-0.00.6
Pavlov. Cond. lever latency6.68.312.33.5-3.3-3.23.0-3.13.02.92.62.61.0
Pavlov. Cond. magazine entry latency0.40.60.9-0.80.80.7-0.90.9-0.9-0.7-0.6-0.5-0.5
Pavlov. Cond. change in total contacts2.42.53.8-1.91.81.7-1.71.7-1.6-1.6-1.5-1.4-0.5
Pavlov. Cond. index score3.14.05.3-2.32.22.1-2.22.3-2.2-2.0-1.7-1.7-1.0
Pavlov. Cond. latency score2.93.74.9-2.22.12.0-2.02.2-2.0-2.0-1.7-1.7-1.0
Pavlov. Cond. lever contacts5.46.48.4-2.92.82.7-2.52.7-2.6-2.6-2.5-2.4-1.2
Pavlov. Cond. magazine entry number0.81.01.41.1-1.1-1.01.2-1.11.11.00.90.80.6
Pavlov. Cond. intertrial magazine entries0.20.30.5-0.60.60.5-0.60.7-0.7-0.5-0.3-0.3-0.2
Pavlov. Cond. lever-magazine prob. diff.3.23.95.1-2.12.12.0-2.22.3-2.2-2.0-1.8-1.7-1.3
Pavlov. Cond. response bias3.13.85.0-2.22.12.0-2.12.1-2.0-2.0-1.8-1.8-0.9
Pavlov. Cond. lever latency3.24.46.01.9-2.1-2.12.3-2.42.42.11.81.71.9
Pavlov. Cond. magazine entry latency0.40.51.00.7-0.7-0.80.4-0.40.50.81.01.00.2
Pavlov. Cond. change in total contacts1.21.63.5-0.71.11.1-1.61.5-1.6-1.2-0.9-0.8-1.9
Pavlov. Cond. index score0.40.51.3-0.30.50.5-0.90.9-0.9-0.6-0.3-0.3-1.1
Pavlov. Cond. latency score0.70.82.0-0.40.70.7-1.01.1-1.1-0.9-0.7-0.7-1.4
Pavlov. Cond. lever contacts1.62.23.5-1.51.51.5-1.61.8-1.9-1.5-1.1-1.1-1.3
Pavlov. Cond. magazine entry number0.20.31.5-0.2-0.2-0.20.6-0.60.50.30.20.11.2
Pavlov. Cond. intertrial magazine entries0.40.60.9-0.80.80.9-0.60.6-0.6-0.8-0.9-1.0-0.4
Pavlov. Cond. lever-magazine prob. diff.0.40.51.4-0.30.50.5-0.90.9-0.9-0.6-0.3-0.3-1.2
Pavlov. Cond. response bias0.71.01.8-0.80.90.9-1.11.2-1.3-0.9-0.6-0.5-1.0
Time in closed arm before self-admin1.92.13.31.8-1.8-1.61.7-1.81.61.30.90.80.4
Time in closed arm after self-admin0.10.10.50.4-0.2-0.20.1-0.20.10.1-0.2-0.2-0.7
Time in open arm before self-admin1.41.53.9-2.01.61.4-1.21.2-1.1-1.1-0.9-0.60.4
Time in open arm after self-admin0.80.92.0-1.41.11.1-0.81.0-0.7-0.9-0.8-0.80.3
Bone: periosteal estimation1.12.33.4-1.81.81.7-1.81.6-1.7-1.5-1.2-1.2-0.2
Bone: periosteal perimeter0.30.51.1-1.00.90.8-0.60.6-0.6-0.5-0.4-0.40.6
Bone: post-yield work0.91.22.8-1.71.41.2-1.21.2-1.2-0.9-0.6-0.50.5
Progressive ratio test 1 active lever presses0.30.31.4-0.50.30.50.4-0.00.0-0.4-1.0-1.2-0.1
Progressive ratio test 1 breakpoint0.40.41.6-0.70.50.70.20.2-0.1-0.6-1.1-1.3-0.2
Progressive ratio test 1 inactive lever presses0.20.31.1-1.00.40.40.3-0.10.1-0.0-0.3-0.50.9
Progressive ratio test 2 active lever presses0.10.10.4-0.2-0.2-0.00.6-0.40.50.2-0.2-0.30.3
Progressive ratio test 2 breakpoint0.20.20.70.0-0.4-0.20.8-0.60.60.3-0.1-0.20.3
Progressive ratio test 2 inactive lever presses0.20.31.0-0.50.40.5-0.20.2-0.4-0.5-0.7-1.0-0.4
Incentive Sensitization - Responses0.10.10.20.1-0.2-0.20.3-0.40.40.30.10.20.5
Incentive Sensitization - Breakpoint0.20.20.30.2-0.4-0.30.4-0.50.60.40.20.30.5
Sum of active levers in priming session hrs 5-63.53.45.11.7-1.9-1.92.2-1.91.91.91.61.61.5
Progressive ratio0.00.00.10.3-0.1-0.10.3-0.0-0.0-0.0-0.0-0.10.1
Food seeking constrained by brief footshock5.26.411.8-3.43.03.0-2.32.5-2.3-2.4-2.4-2.3-0.1
Seeking ratio, punishment vs. effort1.41.73.5-1.91.61.6-1.41.2-1.1-1.1-1.1-1.1-0.2
Retroperitoneal fat weight0.00.10.30.6-0.5-0.50.2-0.30.30.40.30.30.0
Reaction time number correct0.00.10.1-0.20.30.3-0.10.1-0.0-0.1-0.3-0.40.2
Reaction time mean minus median1.41.85.1-0.21.01.0-1.51.6-1.7-1.4-1.1-1.0-2.3
Reaction time mean minus median AUC1.82.43.9-0.91.41.4-1.71.8-1.9-1.6-1.3-1.2-2.0
Reaction time num false alarms0.20.20.7-0.00.20.2-0.20.6-0.5-0.6-0.6-0.6-0.8
Reaction time num false alarms AUC0.50.71.1-0.70.70.7-0.60.9-0.8-1.0-1.0-1.0-0.7
Reaction time trials correct on left0.00.10.1-0.20.30.3-0.10.1-0.0-0.1-0.3-0.40.2
Reaction time trials on left0.00.00.1-0.10.20.2-0.00.00.0-0.1-0.2-0.30.3
Reaction time mean0.60.93.01.7-1.1-1.10.4-0.50.30.60.81.0-0.8
Reaction time mean AUC0.71.03.41.9-1.2-1.20.5-0.60.40.70.81.0-0.8
Median of all reaction times2.02.75.62.4-1.9-2.01.3-1.51.31.61.61.80.2
Reaction time omissions1.31.72.51.6-1.5-1.51.1-1.20.91.21.41.50.8
Reaction time false alarm rate0.10.10.40.1-0.00.00.00.3-0.3-0.3-0.3-0.3-0.7
Reaction time premature initiation rate1.52.04.22.0-1.7-1.51.3-1.51.51.41.21.0-0.5
Reaction time premature initiations0.91.32.91.7-1.3-1.21.1-1.21.31.10.80.7-0.4
Std. dev. reaction times0.30.52.20.60.00.0-0.70.7-0.9-0.5-0.2-0.1-1.5
Reaction time trials completed0.00.00.1-0.10.20.2-0.00.00.0-0.1-0.2-0.30.3
Reaction time trials AUC0.00.00.1-0.10.20.2-0.00.00.0-0.1-0.3-0.30.2
Run reversals in cocaine runway, females0.30.31.30.00.30.3-0.60.4-0.3-0.4-0.4-0.5-1.1
Run reversals in cocaine runway, males0.00.00.10.3-0.10.00.10.2-0.1-0.2-0.4-0.3-0.3
Latency to leave start box in cocaine runway0.90.91.2-0.80.91.0-1.10.8-0.9-1.0-1.1-1.1-0.9
Latency to leave start box in cocaine runway, F0.00.00.00.0-0.1-0.00.0-0.20.20.0-0.1-0.20.0
Latency to leave start box in cocaine runway, M0.90.92.0-1.41.11.1-1.10.7-0.8-0.8-0.8-0.8-0.0
Std. dev. time between licks in bursts0.30.40.60.7-0.7-0.80.7-0.60.70.60.50.50.4
Total sessions with >9 infusions0.30.31.1-0.4-0.2-0.20.8-0.50.60.3-0.1-0.31.0
Short access day 1 total inactive lever presses1.71.93.7-1.61.41.6-0.90.9-0.8-1.4-1.8-1.9-0.7
Short access day 10 total inactive lever presses0.10.10.5-0.50.50.4-0.70.3-0.4-0.2-0.0-0.2-0.1
Short access day 1 total infusions0.60.61.9-1.40.80.9-0.10.2-0.3-0.7-1.0-1.00.5
Short access day 10 total infusions0.40.41.3-1.10.60.70.10.1-0.1-0.5-1.0-1.00.3
Short access total infusions0.20.20.6-0.80.10.20.5-0.30.3-0.1-0.6-0.60.7
Short access day 1 locomotion0.20.20.70.1-0.4-0.30.8-0.70.60.1-0.3-0.3-0.1
Short access day 10 total locomotion0.30.30.90.9-0.7-0.60.6-0.50.40.1-0.2-0.3-0.8
Short access total locomotion0.10.10.4-0.40.00.10.3-0.30.3-0.2-0.6-0.6-0.0
One hour access (0.3 mA shock)0.40.51.3-1.10.70.8-0.20.6-0.4-0.7-0.8-1.0-0.1
Compulsive drug intake0.30.30.7-0.70.60.6-0.30.8-0.7-0.4-0.3-0.20.0
One hour access (shock baseline)0.30.41.2-0.80.50.7-0.10.1-0.1-0.6-0.9-1.1-0.0
Social response proportion2.02.23.31.8-1.6-1.81.1-1.31.11.51.81.80.3
Social responses0.50.71.1-1.00.90.8-1.00.9-1.1-0.8-0.5-0.5-0.3
Social time0.60.82.30.3-0.5-0.90.1-0.40.20.91.51.51.2
Soleus weight0.82.411.2-0.3-0.6-0.90.9-1.11.01.51.81.83.3
Bone: stiffness3.25.07.7-2.52.62.3-2.82.5-2.5-2.2-1.7-1.6-0.9
Tibialis anterior weight5.518.829.9-5.55.14.9-4.74.4-4.4-4.2-3.9-3.8-0.7
Time to tail flick, vehicle, before self-admin0.80.81.71.3-1.2-1.01.1-1.01.00.70.40.30.1
Time to tail flick, vehicle, after self-admin0.00.00.10.1-0.0-0.00.1-0.10.00.1-0.1-0.20.1
Time to tail flick, test, before self-admin0.40.40.7-0.50.60.7-0.40.6-0.5-0.7-0.8-0.8-0.8
Time to tail flick, test, after self-admin1.51.52.6-0.61.01.2-1.11.1-1.1-1.3-1.4-1.6-1.6
Delta time to tail flick, vehicle, before/after SA0.10.10.3-0.50.40.4-0.40.4-0.6-0.2-0.0-0.00.0
Delta time to tail flick, test, before/after SA0.10.00.20.4-0.2-0.1-0.1-0.10.1-0.0-0.1-0.3-0.4
Tibia length0.41.25.0-0.1-0.4-0.70.4-0.71.01.11.31.32.2
Ambulatory time before self-admin2.32.35.4-2.31.91.8-1.31.4-1.4-1.4-1.4-1.20.4
Ambulatory time after self-admin0.10.10.3-0.40.30.2-0.20.5-0.4-0.2-0.1-0.10.5
Bone: tissue strength0.10.10.3-0.30.30.0-0.60.5-0.4-0.00.40.5-0.1
Total heroin consumption0.81.01.90.5-0.8-0.81.1-0.91.21.11.00.91.4
Bone: trabecular number1.62.52.9-1.31.61.6-1.61.6-1.6-1.7-1.6-1.6-1.5
Bone: trabecular spacing0.10.10.40.30.00.1-0.20.1-0.1-0.2-0.2-0.2-0.6
Bone: trabecular thickness0.00.00.10.2-0.3-0.20.3-0.10.10.20.20.2-0.1
Bone: trabecular tissue density1.72.44.1-2.01.91.6-2.01.9-1.9-1.4-0.8-0.70.0
Water consumed over 24 hours0.91.01.4-0.81.11.1-1.10.9-0.9-1.0-1.2-1.2-0.9
Number of responses in last shaping day0.50.52.2-0.7-0.1-0.10.6-0.70.70.60.60.51.5