Hub : Genes

Fabp4

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression Fabp4 0.15 0.07 0.0e+00 0.17 0.16 0.17 0.17 8.1e-25 7.4e-24 4.2e-25 1.2e-24
2 IL gene expression Fabp4 0.71 0.16 5.9e-07 0.04 0.06 0.05 0.04 3.8e-02 1.3e-02 2.8e-02 3.8e-02
3 Adipose alternative TSS XM_063282611.1 0.17 0.1 1.1e-15 0.11 0.1 0.1 0.1 6.5e-12 1.4e-11 1.1e-11 1.9e-11
4 Adipose mRNA stability Fabp4 0.08 0.05 6.7e-08 0.04 0.04 0.04 0.03 1.0e-05 5.2e-05 5.4e-05 9.5e-05
5 PL gene expression Fabp4 0.44 0.14 0.0e+00 0.33 0.32 0.34 0.33 8.4e-37 8.2e-36 8.0e-38 3.5e-37
6 IC gene expression Fabp4 0.1 0.07 1.7e-03 0.05 0.04 0.01 0.04 3.2e-03 9.9e-03 8.0e-02 6.5e-03
7 OFC gene expression Fabp4 0.41 0.18 3.7e-05 0.14 0.11 0.07 0.11 4.3e-04 1.5e-03 1.1e-02 1.4e-03
8 Brain gene expression Fabp4 0.18 0.1 2.3e-12 0.1 0.08 0.09 0.09 1.9e-09 4.7e-08 2.1e-08 5.5e-09
9 BLA gene expression Fabp4 0.42 0.15 0.0e+00 0.26 0.25 0.26 0.27 3.1e-14 1.2e-13 3.1e-14 1.1e-14
10 Adipose alternative TSS NM_053365.3 0.18 0.11 5.0e-16 0.11 0.11 0.11 0.11 3.7e-12 8.1e-12 7.5e-12 9.1e-12
11 pVTA gene expression Fabp4 0.1 0.06 1.3e-07 0.08 0.09 0.11 0.08 3.4e-07 1.1e-07 3.2e-09 7.9e-07
12 Adipose gene expression Fabp4 0.05 0.04 2.1e-03 0.02 0.02 0.01 0.02 2.1e-03 2.5e-03 1.5e-02 3.8e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density1.01.82.61.6-1.41.31.31.51.51.31.4-1.4-1.31.20.6
Area under the delay curve0.50.81.0-0.80.9-0.9-0.9-1.0-1.0-0.9-0.80.90.9-0.7-0.5
BMI with tail0.72.53.4-1.81.7-1.6-1.6-1.7-1.6-1.4-1.61.71.5-1.80.8
BMI without tail0.73.64.2-2.02.1-1.8-1.8-2.0-1.9-1.9-2.02.01.9-2.11.3
Body weight1.25.26.3-2.42.5-2.3-2.3-2.3-2.2-2.4-2.22.12.0-2.52.0
Weight adjusted by age0.10.30.5-0.40.3-0.2-0.2-0.5-0.5-0.6-0.50.70.7-0.70.6
Bone surface1.63.24.52.1-1.71.81.81.81.81.71.9-1.7-1.71.41.8
Bone volume1.42.83.92.0-1.71.71.71.81.81.61.6-1.5-1.41.31.9
Breakpoint value in progressive ratio session0.51.01.5-0.71.0-1.0-1.0-1.0-1.1-0.9-1.21.11.0-0.90.6
Number of licking bursts0.10.50.70.8-0.70.60.60.80.80.80.6-0.6-0.70.6-0.0
Context. condit. distance diff. score0.10.10.3-0.30.4-0.3-0.3-0.2-0.2-0.10.1-0.00.10.0-0.5
Locomotion velocity, session 12.42.73.3-1.81.8-1.8-1.8-1.7-1.7-1.7-1.61.61.6-1.70.3
Locomotion distance, session 11.21.62.0-1.21.4-1.3-1.3-1.2-1.2-1.3-1.21.21.2-1.41.1
Locomotion velocity, session 22.32.83.2-1.81.7-1.7-1.7-1.7-1.7-1.7-1.81.81.8-1.70.5
Locomotion distance, session 21.72.43.7-1.41.5-1.5-1.5-1.4-1.4-1.5-1.61.51.5-1.71.9
Locomotion velocity, session 30.00.00.3-0.10.0-0.1-0.1-0.0-0.0-0.1-0.0-0.00.00.0-0.5
Locomotion distance, session 30.20.20.30.6-0.50.50.50.50.50.50.3-0.5-0.40.30.4
Stereotopy head waving bouts, day 30.10.21.0-0.20.4-0.2-0.2-0.3-0.3-0.3-0.20.30.4-0.41.0
Stereotopy head waving duration, day 30.40.50.7-0.80.8-0.8-0.8-0.8-0.8-0.7-0.60.80.8-0.70.3
Locomotion velocity, session 73.94.36.12.5-1.91.81.82.22.22.12.2-2.2-2.21.82.0
Locomotion distance, session 74.65.87.92.8-2.42.32.32.62.62.52.7-2.6-2.62.50.5
Stereotopy head waving bouts, day 70.91.01.4-1.11.0-0.9-0.9-1.1-1.1-1.0-1.11.11.1-1.20.7
Stereotopy head waving duration, day 71.21.41.9-1.31.2-1.1-1.1-1.3-1.3-1.2-1.31.21.2-1.40.3
Locomotion velocity, session 84.04.86.1-2.52.4-2.3-2.3-2.3-2.3-2.3-2.12.22.2-2.20.2
Locomotion distance, session 81.31.93.0-1.51.7-1.6-1.6-1.5-1.5-1.4-1.11.21.3-1.30.8
Degree of sensitization distance0.40.40.70.7-0.50.50.50.70.70.60.8-0.7-0.70.80.1
Degree of sensitization stereotypy1.92.12.6-1.61.4-1.4-1.4-1.6-1.6-1.4-1.61.51.5-1.60.5
Conditioned locomotion0.20.20.3-0.50.4-0.5-0.5-0.4-0.4-0.4-0.50.40.5-0.50.2
Cocaine response after cond. corrected0.60.91.11.0-0.91.01.01.01.00.91.0-0.9-0.91.0-0.4
Cocaine response after cond. not corrected1.21.72.21.4-1.41.51.51.31.41.21.3-1.2-1.21.3-0.5
Cocaine response before conditioning0.20.30.50.6-0.70.70.70.50.50.50.4-0.4-0.50.30.2
Saline control response0.30.41.70.6-0.60.60.60.50.50.50.6-0.5-0.50.31.3
Bone: connectivity density1.52.43.31.8-1.41.41.41.61.71.61.8-1.8-1.71.60.3
Bone: cortical apparent density0.81.21.9-1.31.2-1.4-1.4-1.1-1.1-1.0-1.21.00.9-1.0-0.4
Bone: cortical area0.20.41.9-0.30.1-0.2-0.2-0.3-0.3-0.6-0.50.80.7-0.71.4
Bone: cortical porosity0.10.10.30.2-0.30.30.30.10.10.20.1-0.0-0.1-0.00.5
Bone: cortical porosity0.10.10.4-0.10.0-0.0-0.0-0.2-0.2-0.1-0.20.30.3-0.30.6
Bone: cortical thickness0.71.12.0-0.80.8-0.9-0.9-0.9-0.9-1.1-1.11.21.2-1.21.4
Bone: cortical thickness4.15.06.9-2.31.9-2.2-2.2-2.2-2.2-2.5-2.52.62.6-2.30.7
Bone: cortical tissue density0.81.21.9-1.31.2-1.4-1.4-1.1-1.1-1.0-1.21.00.9-1.0-0.5
Condit. Reinf. active minus inactive responses5.76.48.3-2.52.4-2.4-2.4-2.4-2.4-2.5-2.72.62.6-2.92.6
Condit. Reinf. active-inactive response ratio7.47.910.2-2.72.7-2.6-2.6-2.8-2.8-2.8-2.92.82.8-3.22.8
Condit. Reinf. active responses4.25.57.4-2.22.2-2.2-2.2-2.2-2.2-2.3-2.42.42.3-2.72.7
Condit. Reinf. inactive responses0.00.10.1-0.20.2-0.2-0.2-0.2-0.2-0.3-0.20.20.3-0.20.3
Incentive salience index mean5.67.29.3-2.62.6-2.6-2.6-2.6-2.6-2.7-2.82.72.7-3.02.7
Condit. Reinf. lever presses2.53.84.6-2.02.0-2.1-2.1-1.9-1.9-1.9-1.91.91.9-2.21.7
Condit. Reinf. active minus inactive responses1.42.14.41.7-1.41.61.61.41.31.31.3-1.2-1.31.02.1
Condit. Reinf. active-inactive response ratio0.60.93.41.1-0.81.01.00.80.80.80.7-0.7-0.80.51.8
Condit. Reinf. active responses2.33.34.82.1-1.82.02.01.71.71.61.7-1.6-1.71.32.2
Condit. Reinf. inactive responses0.10.20.30.4-0.30.50.50.40.30.30.6-0.4-0.40.30.6
Condit. Reinf. lever presses1.01.42.11.5-1.21.11.11.31.31.11.1-0.9-1.10.91.5
Condit. Reinf. lever reinforcers received2.43.44.72.2-1.92.12.11.81.81.71.8-1.6-1.71.42.1
Conditioned reinforcement - actives1.66.28.52.9-2.32.22.22.82.72.92.7-2.7-2.62.11.0
Conditioned reinforcement - inactives0.10.30.60.7-0.50.60.60.40.50.80.5-0.5-0.40.50.5
Conditioned locomotion2.02.94.81.8-1.51.31.32.02.02.22.0-1.9-1.91.20.8
Patch foraging indifference point 0 sec0.51.52.01.2-1.41.21.21.11.01.21.3-1.1-0.91.4-1.3
Patch foraging indifference point AUC0.10.20.4-0.60.4-0.5-0.5-0.4-0.3-0.6-0.50.40.5-0.4-0.2
Delay disc. indifference point, 0s delay0.10.10.30.1-0.20.20.20.40.30.50.6-0.5-0.40.2-0.4
Delay disc. indifference point, 16s delay0.40.60.8-0.60.8-0.8-0.8-0.9-0.9-0.9-0.80.90.8-0.3-0.3
Delay disc. indifference point, 2s delay1.01.22.5-0.91.1-1.2-1.2-0.9-1.0-1.0-0.90.80.9-1.21.6
Delay disc. indifference point, 24s delay0.10.10.2-0.10.2-0.1-0.1-0.4-0.4-0.4-0.30.50.3-0.0-0.3
Delay disc. indifference point, 4s delay1.71.82.2-1.41.4-1.4-1.4-1.4-1.5-1.4-1.31.31.4-1.3-0.3
Delay disc. indifference point, 8s delay0.10.11.0-0.1-0.10.10.1-0.2-0.2-0.1-0.10.30.1-0.1-1.0
Indifference point function ln k0.00.00.1-0.10.3-0.2-0.2-0.2-0.3-0.00.10.00.10.0-0.4
Indifference point function log k0.00.00.1-0.10.3-0.2-0.2-0.2-0.3-0.00.10.00.10.0-0.4
Patch foraging total patch changes 0 sec0.30.92.10.9-1.00.90.90.80.70.81.0-0.8-0.61.2-1.5
Patch foraging total patch changes 12 sec0.30.41.40.4-0.70.60.60.50.40.50.6-0.5-0.30.7-1.2
Patch foraging total patch changes 18 sec0.20.51.2-0.70.5-0.6-0.6-0.6-0.7-0.9-0.80.91.1-0.5-0.6
Patch foraging total patch changes 24 sec0.00.10.90.0-0.1-0.1-0.10.20.20.10.3-0.3-0.10.3-1.0
Patch foraging total patch changes 6 sec0.10.11.2-0.2-0.10.00.0-0.2-0.2-0.1-0.00.10.30.2-1.1
Patch foraging time to switch 0 sec0.72.54.9-1.21.6-1.5-1.5-1.6-1.6-1.4-1.51.61.5-1.72.2
Patch foraging water rate 0 sec0.10.32.60.1-0.40.40.40.30.30.20.3-0.4-0.40.7-1.6
Patch foraging water rate 12 sec0.62.43.21.7-1.71.71.71.51.61.41.6-1.5-1.51.8-1.0
Patch foraging water rate 18 sec0.20.50.60.6-0.70.80.80.70.70.70.7-0.7-0.70.6-0.2
Patch foraging water rate 24 sec0.10.21.7-0.0-0.10.30.30.20.20.00.3-0.1-0.40.5-1.3
Patch foraging water rate 6 sec2.13.23.61.9-1.91.81.81.91.81.71.9-1.9-1.91.9-0.8
Seeking ratio, delayed vs. immediate footshock7.010.011.73.1-3.43.33.33.33.23.33.4-3.3-3.43.2-1.4
Distance traveled before self-admin0.30.61.1-0.81.0-1.1-1.1-0.8-0.7-0.7-0.70.70.8-0.7-0.1
Distance traveled after self-admin0.10.10.20.3-0.30.40.40.20.30.30.3-0.3-0.30.4-0.4
Extensor digitorum longus weight11.244.753.7-7.17.3-7.2-7.2-7.1-7.1-6.9-6.56.66.7-6.62.7
Bone: elastic displacement0.20.32.6-0.10.3-0.2-0.2-0.2-0.3-0.2-0.30.20.3-0.51.6
Bone: elastic work0.20.33.00.2-0.00.10.10.00.0-0.0-0.10.10.1-0.41.7
Bone: endosteal estimation0.40.94.11.0-0.70.90.90.80.80.80.8-0.7-0.70.42.0
Bone: endosteal perimeter0.30.81.01.0-0.91.01.00.90.90.90.9-0.8-1.00.70.8
Epididymis fat weight0.21.22.0-1.31.4-1.4-1.4-1.0-1.0-1.2-1.20.90.9-1.0-0.1
Delta time in closed arm before/after self-admin0.10.10.6-0.4-0.1-0.0-0.00.40.30.30.4-0.4-0.3-0.1-0.7
Delta time in open arm before/after self-admin0.20.20.50.7-0.40.50.50.20.30.30.5-0.4-0.20.60.1
Diff in mean of infusions in LGA sessions1.11.92.8-0.91.4-1.3-1.3-1.4-1.5-1.4-1.51.51.5-1.11.7
Delay discount exponential model param0.40.60.80.7-0.80.80.80.90.90.80.8-0.8-0.80.60.5
Extinction: sum of active levers before priming0.10.20.3-0.30.1-0.3-0.3-0.3-0.4-0.5-0.60.50.4-0.60.4
Active lever presses in extinction session 60.20.20.60.5-0.50.40.40.40.20.30.0-0.2-0.30.4-0.8
Bone: final force0.30.53.0-0.40.3-0.2-0.2-0.4-0.4-0.6-0.60.80.7-0.91.7
Bone: final moment0.20.32.70.0-0.10.10.1-0.1-0.1-0.2-0.20.40.3-0.41.6
Food consumed during 24 hour testing period1.22.42.8-1.71.6-1.5-1.5-1.6-1.6-1.6-1.71.61.6-1.60.7
Glucose1.21.92.7-1.41.3-1.2-1.2-1.5-1.5-1.5-1.51.71.5-1.40.6
Heart weight0.30.50.7-0.90.6-0.7-0.7-0.7-0.7-0.7-0.80.60.5-0.6-0.6
Delay discount hyperbolic model param0.81.11.41.0-1.11.11.11.11.21.11.0-1.1-1.11.00.1
Intermittent access intake day 1-15 change0.84.65.32.3-2.22.22.22.32.32.22.2-2.2-2.22.1-0.6
Intermittent access intake escalation1.05.56.32.5-2.42.42.42.52.52.52.4-2.4-2.52.4-1.0
Intermittent access intake escalation 24.47.48.52.9-2.92.92.92.92.92.82.8-2.8-2.82.6-0.8
Intermitt. access day 1 inactive lever presses0.22.03.3-1.81.5-1.4-1.4-1.5-1.4-1.3-1.51.41.4-1.2-0.9
Intermitt. access day 15 inactive lever presses0.10.63.6-0.70.3-0.1-0.1-0.7-0.7-0.6-0.50.70.7-0.1-1.9
Intermitt. access escalation Index0.20.71.7-1.00.8-0.8-0.8-0.9-1.0-0.8-0.80.80.8-0.2-1.3
Intermittent access day 1 total infusions1.13.24.52.1-2.12.12.11.81.81.81.8-1.7-1.61.60.5
Intermittent access day 15 total infusions4.410.713.83.7-3.53.53.53.43.43.33.3-3.3-3.23.3-0.4
Intermittent access terminal intake (last 3 days)6.411.114.73.8-3.83.83.83.53.53.23.2-3.1-3.23.3-0.5
Intermittent access total infusions5.76.88.93.0-2.92.92.92.82.72.62.5-2.5-2.52.4-0.2
Intermittent access day 1 locomotion0.61.02.11.2-1.21.41.40.90.80.90.9-0.8-0.61.10.2
Intermittent access day 15 total locomotion0.31.11.91.1-1.31.41.41.11.11.20.9-0.9-0.90.70.5
Intermittent access total locomotion2.02.44.21.7-1.92.02.01.51.51.61.4-1.3-1.31.30.0
Intermittent access standard deviation1.47.28.52.7-2.82.62.62.92.92.82.8-2.8-2.92.8-1.4
Left kidney weight0.00.21.00.2-0.40.50.50.20.30.20.3-0.5-0.50.7-1.0
Right kidney weight0.00.30.6-0.60.6-0.4-0.4-0.8-0.8-0.7-0.60.50.6-0.3-0.4
Cocaine induced anxiety0.10.40.5-0.60.5-0.6-0.6-0.6-0.6-0.7-0.70.70.7-0.4-0.5
Post-drug Anxiety1.92.13.3-1.51.7-1.8-1.8-1.4-1.4-1.4-1.41.41.3-1.40.5
Baseline Anxiety0.30.41.2-0.60.7-0.8-0.8-0.5-0.6-0.5-0.50.40.2-0.81.1
Tail length0.42.23.4-1.51.6-1.3-1.3-1.6-1.5-1.8-1.51.31.5-1.41.3
Length with tail0.41.82.7-1.31.5-1.5-1.5-1.3-1.3-1.6-1.21.01.0-1.31.6
Length without tail0.00.20.60.2-0.1-0.2-0.20.30.40.30.4-0.4-0.60.20.8
Times rat made contact with spout0.10.10.20.4-0.40.40.40.30.30.20.2-0.2-0.20.3-0.2
Lifetime Intake4.75.97.52.7-2.72.72.72.62.52.52.4-2.3-2.32.3-0.7
Liver weight, left0.50.81.2-0.80.9-0.8-0.8-0.9-0.9-0.9-0.90.90.9-0.91.1
Liver weight, right0.20.31.9-0.50.2-0.4-0.4-0.4-0.4-0.5-0.20.40.4-0.1-1.4
Locomotor activity0.00.00.0-0.20.1-0.2-0.2-0.1-0.0-0.00.0-0.00.1-0.10.0
Locomotor testing distance0.00.00.2-0.10.2-0.3-0.3-0.2-0.1-0.2-0.10.20.2-0.20.4
Locomotor testing rearing0.31.21.71.1-1.31.31.31.11.10.91.2-1.0-1.01.0-0.5
Locomotion in novel chamber0.91.22.2-1.00.8-1.0-1.0-0.9-1.1-0.9-1.11.31.2-1.51.0
Locomotion in novel chamber post-restriction0.00.00.3-0.40.0-0.0-0.0-0.1-0.2-0.1-0.10.10.1-0.0-0.6
Fecal boli incidents, locomotor time 10.10.20.4-0.50.5-0.4-0.4-0.6-0.6-0.6-0.40.50.6-0.40.0
Change in fecal boli incidents, locomotor task2.72.93.61.8-1.81.61.61.91.81.81.7-1.9-1.91.5-0.5
Time >=10cm from walls, locomotor time 10.91.11.51.1-1.21.21.21.11.11.21.1-1.0-1.00.60.2
Bouts of movement, locomotor time 10.50.76.7-0.1-0.30.20.20.40.40.30.4-0.4-0.50.4-2.6
Total resting periods, locomotor time 10.50.54.5-0.0-0.40.20.20.50.50.40.5-0.5-0.60.4-2.1
Rest time, locomotor task time 10.10.20.9-0.2-0.20.10.10.40.40.40.4-0.5-0.40.3-1.0
Distance moved, locomotor task time 10.00.00.10.10.2-0.2-0.2-0.2-0.2-0.3-0.30.30.2-0.20.2
Vertical activity count, locomotor time 10.00.22.00.20.3-0.4-0.4-0.2-0.2-0.1-0.30.30.2-0.31.4
Time >=10cm from walls, locomotor time 20.20.51.00.6-0.70.90.90.60.60.60.7-0.5-0.70.21.0
Bouts of movement, locomotor time 20.20.53.9-0.70.5-0.5-0.5-0.5-0.5-0.5-0.30.40.3-0.2-2.0
Total resting periods, locomotor time 20.10.64.5-0.70.4-0.5-0.5-0.4-0.5-0.5-0.30.40.3-0.2-2.1
Rest time, locomotor task time 20.10.20.9-0.30.2-0.4-0.4-0.2-0.3-0.3-0.30.30.3-0.2-1.0
Distance moved, locomotor task time 20.00.00.10.0-0.20.10.10.10.1-0.10.10.1-0.10.1-0.2
Vertical activity count, locomotor time 20.61.41.9-1.21.1-1.1-1.1-1.2-1.2-1.2-1.21.21.1-1.41.0
Light reinforcement 10.41.62.5-1.51.0-1.1-1.1-1.3-1.3-1.4-1.41.41.6-1.2-0.8
Light reinforcement 21.63.54.4-2.01.8-1.9-1.9-2.0-2.0-1.9-2.02.12.1-1.70.1
Bone: marrow area0.30.74.30.9-0.50.70.70.70.70.60.7-0.5-0.60.32.1
Bone: maximum diameter0.00.10.20.3-0.50.50.50.20.30.00.10.20.1-0.00.3
Bone: maximum force0.20.43.2-0.20.1-0.1-0.1-0.3-0.3-0.5-0.50.70.5-0.81.8
Bone: maximum moment0.10.32.80.3-0.20.30.30.10.1-0.1-0.00.20.1-0.31.7
Mean time between licks in bursts0.21.02.9-0.81.1-1.0-1.0-0.9-0.8-0.8-0.90.80.7-1.11.7
Mean num. licks in bursts0.10.20.3-0.50.4-0.3-0.3-0.5-0.6-0.6-0.40.40.5-0.3-0.2
Cd content in liver0.40.50.9-0.80.4-0.5-0.5-0.6-0.6-0.6-0.90.70.7-0.6-1.0
Co content in liver0.20.32.8-0.30.2-0.3-0.3-0.1-0.1-0.1-0.10.10.30.2-1.7
Cu content in liver3.23.84.32.0-2.12.12.12.02.02.02.0-2.0-1.92.0-1.2
Fe content in liver0.50.60.70.8-0.80.80.80.70.70.80.8-0.8-0.80.60.6
K content in liver0.70.71.00.8-0.60.70.70.80.80.81.0-1.0-0.91.0-0.8
Mg content in liver0.60.60.90.8-0.60.60.60.80.80.81.0-0.9-0.80.9-0.4
Mn content in liver0.00.10.1-0.20.4-0.3-0.3-0.2-0.2-0.20.1-0.10.10.1-0.2
Na content in liver1.11.31.61.2-1.11.31.31.01.01.01.2-1.2-1.21.3-0.6
Rb content in liver0.10.10.30.2-0.30.10.10.30.30.20.2-0.10.10.2-0.6
Se content in liver0.00.10.40.00.10.10.1-0.0-0.00.00.3-0.20.00.3-0.6
Sr content in liver0.30.20.7-0.30.8-0.6-0.6-0.5-0.6-0.20.1-0.2-0.1-0.20.8
Zn content in liver2.93.44.01.9-1.91.81.81.81.81.91.9-1.9-1.92.0-1.3
Bone: minimum diameter0.81.612.1-0.40.7-0.5-0.5-0.7-0.7-0.9-0.81.00.9-1.33.5
Time in familiar zone, hab. session 10.60.71.90.6-0.60.50.50.80.80.80.9-0.8-0.81.0-1.4
Time in novel zone, hab. session 10.10.10.2-0.1-0.10.20.2-0.3-0.3-0.3-0.40.30.4-0.30.3
Total zone transitions, hab. session 11.21.72.2-1.31.4-1.5-1.5-1.3-1.3-1.2-1.31.21.2-1.51.1
Total locomotion distance, hab. session 10.40.62.6-0.50.7-0.8-0.8-0.6-0.6-0.6-0.60.60.6-0.81.6
Locomotion velocity, hab. session 10.91.33.3-0.91.1-1.1-1.1-1.0-1.0-1.0-1.01.01.0-1.31.8
Time in familiar zone, hab. session 21.72.05.01.1-1.31.11.11.41.41.41.3-1.3-1.31.6-2.2
Time in novel zone, hab. session 20.60.62.8-0.50.5-0.3-0.3-0.8-0.8-0.8-0.70.70.7-0.91.7
Total zone transitions, hab. session 20.40.60.9-1.00.9-1.0-1.0-0.7-0.7-0.7-0.60.60.7-0.7-0.5
Total locomotion distance, hab. session 20.20.30.5-0.60.5-0.5-0.5-0.5-0.5-0.5-0.60.50.6-0.70.6
Locomotion velocity, hab. session 20.10.20.3-0.40.4-0.4-0.4-0.4-0.3-0.4-0.40.40.5-0.60.5
Novel to familiar place preference ratio0.00.00.30.00.10.10.1-0.2-0.2-0.2-0.10.10.1-0.10.5
Novelty place preference0.00.00.10.2-0.10.30.3-0.0-0.0-0.10.1-0.0-0.00.10.2
Time in novel zone, NPP test0.00.00.10.0-0.00.30.3-0.1-0.1-0.2-0.00.10.10.1-0.1
Total zone transitions, NPP test1.01.52.4-1.41.5-1.5-1.5-1.2-1.2-1.1-1.01.01.0-1.20.0
Total locomotion distance, NPP test0.50.70.9-0.80.9-0.9-0.9-0.7-0.7-0.8-0.80.80.8-0.91.0
Locomotion velocity, NPP test0.20.31.2-0.40.5-0.6-0.6-0.4-0.4-0.5-0.50.50.5-0.71.1
Intraocular pressure2.03.34.3-1.91.9-1.9-1.9-1.8-1.8-1.8-1.71.71.7-2.11.4
Delta distance traveled before/after self-admin3.33.65.22.1-2.02.32.31.81.91.81.9-1.8-2.01.9-0.0
Delta ambulatory time before/after self-admin2.23.85.62.1-2.12.42.41.91.91.92.0-1.9-2.01.9-0.1
Parametrial fat weight0.10.10.3-0.30.4-0.5-0.5-0.3-0.3-0.2-0.20.30.3-0.50.5
Pavlov. Cond. lever latency0.60.71.00.8-0.90.90.90.80.80.80.8-0.8-0.91.0-1.0
Pavlov. Cond. magazine entry latency0.30.40.6-0.60.6-0.7-0.7-0.5-0.5-0.6-0.60.60.7-0.80.8
Pavlov. Cond. change in total contacts2.83.03.7-1.81.8-1.8-1.8-1.7-1.7-1.7-1.71.71.8-1.91.3
Pavlov. Cond. index score0.91.11.3-1.11.1-1.1-1.1-1.0-1.0-1.0-1.01.01.1-1.20.6
Pavlov. Cond. latency score0.81.01.2-1.01.0-1.1-1.1-0.9-0.9-1.0-1.01.01.1-1.10.5
Pavlov. Cond. lever contacts0.80.91.9-0.81.0-1.0-1.0-0.9-0.9-0.8-0.80.80.9-1.11.4
Pavlov. Cond. magazine entry number0.91.21.41.2-1.11.21.21.01.01.11.1-1.1-1.21.2-0.5
Pavlov. Cond. intertrial magazine entries0.50.60.80.8-0.70.70.70.80.80.80.9-0.9-0.80.70.2
Pavlov. Cond. lever-magazine prob. diff.0.81.01.2-1.01.0-1.0-1.0-0.9-0.9-1.0-1.01.01.1-1.10.6
Pavlov. Cond. response bias0.91.11.5-1.01.1-1.1-1.1-1.0-1.0-1.0-1.01.01.1-1.21.2
Pavlov. Cond. lever latency1.21.72.4-1.51.4-1.3-1.3-1.5-1.5-1.4-1.31.11.4-1.4-0.0
Pavlov. Cond. magazine entry latency0.00.00.10.1-0.20.10.10.20.2-0.0-0.10.20.0-0.10.3
Pavlov. Cond. change in total contacts0.10.33.40.5-0.20.20.20.30.20.20.2-0.0-0.3-0.11.8
Pavlov. Cond. index score0.20.31.30.7-0.50.40.40.60.60.40.3-0.1-0.40.21.2
Pavlov. Cond. latency score0.30.50.90.9-0.70.60.60.80.80.60.5-0.4-0.60.50.9
Pavlov. Cond. lever contacts0.71.01.51.2-1.00.90.91.21.21.11.1-0.8-1.11.00.3
Pavlov. Cond. magazine entry number0.00.10.5-0.0-0.00.10.10.00.00.10.2-0.3-0.10.2-0.7
Pavlov. Cond. intertrial magazine entries0.20.40.7-0.50.7-0.7-0.7-0.6-0.6-0.5-0.40.40.5-0.60.8
Pavlov. Cond. lever-magazine prob. diff.0.20.31.10.7-0.50.40.40.60.60.50.4-0.2-0.50.31.0
Pavlov. Cond. response bias0.30.40.90.8-0.60.60.60.70.70.60.5-0.3-0.60.51.0
Time in closed arm before self-admin0.71.22.41.1-1.11.21.20.91.01.01.0-1.0-0.91.6-0.8
Time in closed arm after self-admin0.40.42.10.1-0.50.50.50.60.60.60.5-0.6-0.50.7-1.4
Time in open arm before self-admin0.10.11.10.10.0-0.1-0.10.0-0.1-0.1-0.10.10.2-0.41.0
Time in open arm after self-admin0.50.51.1-0.30.8-0.7-0.7-0.8-0.8-0.8-0.60.71.0-0.50.7
Bone: periosteal estimation0.30.67.00.2-0.10.20.20.00.0-0.2-0.10.40.3-0.62.6
Bone: periosteal perimeter0.10.20.80.5-0.60.60.60.40.40.30.4-0.1-0.20.20.9
Bone: post-yield work2.95.06.22.4-2.52.52.52.42.42.12.3-2.2-2.22.2-0.6
Progressive ratio test 1 active lever presses1.42.43.51.6-1.81.91.91.51.51.51.5-1.4-1.51.5-0.7
Progressive ratio test 1 breakpoint1.42.43.61.6-1.81.91.91.61.51.51.5-1.4-1.51.5-0.7
Progressive ratio test 1 inactive lever presses0.00.00.10.1-0.10.30.30.00.10.00.0-0.00.1-0.10.2
Progressive ratio test 2 active lever presses4.05.77.42.7-2.52.42.42.62.52.62.5-2.5-2.42.10.4
Progressive ratio test 2 breakpoint4.25.47.12.7-2.52.42.42.52.42.62.4-2.4-2.42.00.4
Progressive ratio test 2 inactive lever presses0.51.62.51.6-1.51.51.51.31.21.31.2-1.2-1.01.3-0.2
Incentive Sensitization - Responses1.02.84.22.1-1.71.51.51.91.81.91.7-1.8-1.61.11.4
Incentive Sensitization - Breakpoint1.32.94.42.1-1.71.51.51.91.82.01.8-1.8-1.61.21.3
Sum of active levers in priming session hrs 5-60.70.61.01.0-0.80.50.51.00.91.00.6-0.8-0.80.60.8
Progressive ratio0.41.13.90.5-1.11.11.11.00.90.80.8-1.1-1.10.9-2.0
Food seeking constrained by brief footshock3.54.45.3-2.02.2-2.3-2.3-2.0-2.0-2.0-1.92.22.0-2.22.0
Seeking ratio, punishment vs. effort1.84.06.7-1.52.2-2.2-2.2-1.9-1.8-1.7-1.72.01.9-1.92.6
Retroperitoneal fat weight0.20.81.3-1.01.0-1.1-1.1-0.8-0.7-0.9-0.90.80.8-1.00.5
Reaction time number correct0.10.51.70.7-0.60.70.70.70.70.70.7-0.6-0.50.41.3
Reaction time mean minus median0.63.65.1-2.21.7-1.8-1.8-2.0-2.0-1.8-2.02.32.0-1.9-0.9
Reaction time mean minus median AUC0.74.66.7-2.41.9-2.0-2.0-2.3-2.3-2.1-2.42.62.3-2.3-0.4
Reaction time num false alarms0.91.62.11.5-1.21.41.41.31.21.21.2-1.2-1.10.91.3
Reaction time num false alarms AUC0.71.72.31.5-1.31.51.51.31.31.31.2-1.2-1.11.01.1
Reaction time trials correct on left0.10.51.70.7-0.60.70.70.70.70.70.7-0.6-0.50.41.3
Reaction time trials on left0.10.41.80.6-0.50.60.60.60.60.60.6-0.5-0.40.31.3
Reaction time mean1.32.94.6-1.71.5-1.7-1.7-1.6-1.7-1.5-1.92.11.9-1.90.4
Reaction time mean AUC1.33.15.0-1.71.6-1.6-1.6-1.7-1.8-1.6-2.02.22.0-2.00.6
Median of all reaction times1.32.13.3-1.31.3-1.4-1.4-1.3-1.3-1.3-1.61.81.6-1.71.0
Reaction time omissions4.16.78.2-2.82.5-2.5-2.5-2.8-2.8-2.9-2.82.92.8-2.60.3
Reaction time false alarm rate0.30.40.60.8-0.70.80.80.70.60.60.6-0.6-0.60.6-0.1
Reaction time premature initiation rate1.42.22.91.3-1.51.41.41.41.31.51.4-1.6-1.61.5-1.7
Reaction time premature initiations0.82.32.71.5-1.61.51.51.51.41.61.6-1.6-1.61.5-1.0
Std. dev. reaction times0.72.33.9-1.71.2-1.4-1.4-1.6-1.6-1.5-1.72.01.7-1.5-0.7
Reaction time trials completed0.10.41.80.6-0.50.60.60.60.60.60.6-0.5-0.40.31.3
Reaction time trials AUC0.10.32.00.5-0.40.50.50.50.50.50.5-0.4-0.30.21.4
Run reversals in cocaine runway, females0.40.40.8-0.60.7-0.9-0.9-0.6-0.6-0.5-0.80.60.5-0.60.3
Run reversals in cocaine runway, males2.42.63.0-1.51.6-1.7-1.7-1.7-1.7-1.7-1.71.71.7-1.71.0
Latency to leave start box in cocaine runway0.81.01.31.0-1.01.11.11.01.01.11.1-1.0-1.11.1-0.3
Latency to leave start box in cocaine runway, F3.13.94.72.0-2.02.02.02.12.12.22.1-2.1-2.12.0-0.5
Latency to leave start box in cocaine runway, M2.62.53.2-1.81.6-1.6-1.6-1.6-1.6-1.6-1.61.71.6-1.60.4
Std. dev. time between licks in bursts0.00.10.80.10.1-0.2-0.2-0.00.00.10.10.0-0.1-0.20.9
Total sessions with >9 infusions2.12.63.61.8-1.81.91.91.61.61.71.5-1.4-1.31.6-1.1
Short access day 1 total inactive lever presses0.81.63.21.0-1.31.21.21.11.21.31.1-1.2-1.21.3-1.8
Short access day 10 total inactive lever presses0.10.40.9-0.90.8-0.8-0.8-0.4-0.3-0.2-0.30.20.2-0.4-1.0
Short access day 1 total infusions1.53.03.71.7-1.91.61.61.91.91.81.7-1.7-1.61.6-1.5
Short access day 10 total infusions2.13.54.92.2-2.02.22.21.81.81.81.9-1.8-1.71.9-0.6
Short access total infusions1.92.73.81.8-1.92.02.01.61.61.61.5-1.5-1.51.6-0.9
Short access day 1 locomotion0.20.40.60.6-0.80.80.80.50.50.50.4-0.3-0.30.6-0.8
Short access day 10 total locomotion0.10.30.5-0.50.5-0.4-0.4-0.7-0.7-0.6-0.70.70.7-0.5-0.3
Short access total locomotion0.40.61.30.8-1.01.21.20.70.60.70.6-0.5-0.50.7-0.3
One hour access (0.3 mA shock)5.56.57.92.8-2.62.62.62.72.72.72.8-2.7-2.62.30.4
Compulsive drug intake0.50.81.6-1.01.3-1.2-1.2-0.9-1.0-0.7-0.60.60.6-0.6-0.0
One hour access (shock baseline)4.010.413.33.6-3.63.63.63.43.43.23.2-3.2-3.13.00.4
Social response proportion0.30.40.7-0.70.5-0.4-0.4-0.8-0.8-0.6-0.50.70.8-0.3-0.4
Social responses0.70.91.4-1.10.8-0.8-0.8-1.0-1.1-1.0-1.01.11.2-0.7-0.7
Social time0.10.10.20.1-0.30.50.5-0.2-0.1-0.2-0.30.40.5-0.10.3
Soleus weight1.02.93.8-1.71.7-1.6-1.6-1.8-1.8-1.9-1.81.82.0-1.70.9
Bone: stiffness0.10.30.7-0.40.2-0.2-0.2-0.4-0.4-0.6-0.50.70.6-0.60.8
Tibialis anterior weight9.231.737.3-5.86.1-5.8-5.8-5.9-5.9-5.8-5.65.55.7-5.83.3
Time to tail flick, vehicle, before self-admin0.30.40.70.5-0.50.20.20.80.80.80.7-0.8-0.70.40.7
Time to tail flick, vehicle, after self-admin1.73.44.52.1-1.71.71.71.92.02.12.0-2.0-2.11.9-0.2
Time to tail flick, test, before self-admin0.10.10.8-0.10.0-0.1-0.10.0-0.0-0.20.1-0.10.30.3-0.9
Time to tail flick, test, after self-admin1.51.62.71.3-1.51.61.61.21.21.01.1-1.2-1.11.4-0.6
Delta time to tail flick, vehicle, before/after SA2.72.83.51.9-1.71.91.91.61.71.81.7-1.6-1.91.6-0.5
Delta time to tail flick, test, before/after SA0.00.00.10.1-0.20.30.3-0.1-0.10.1-0.20.2-0.10.0-0.2
Tibia length1.23.44.31.9-1.81.81.82.02.01.82.1-1.9-1.92.1-1.0
Ambulatory time before self-admin0.41.42.2-1.21.3-1.5-1.5-1.2-1.0-1.1-1.11.11.2-1.20.1
Ambulatory time after self-admin0.20.40.70.8-0.60.80.80.40.60.60.7-0.6-0.60.60.2
Bone: tissue strength3.13.34.81.8-1.92.22.21.71.61.81.8-1.9-2.01.7-0.8
Total heroin consumption0.10.10.90.5-0.20.30.30.20.10.10.2-0.2-0.10.11.0
Bone: trabecular number0.50.91.31.1-1.00.80.81.11.10.90.9-1.0-0.90.90.1
Bone: trabecular spacing0.91.31.8-1.31.2-1.1-1.1-1.3-1.3-1.2-1.21.21.2-1.1-0.5
Bone: trabecular thickness1.42.02.81.7-1.61.51.51.61.61.41.1-1.2-1.31.01.0
Bone: trabecular tissue density2.33.95.4-2.21.7-1.8-1.8-2.1-2.1-2.1-2.32.32.2-2.1-0.5
Water consumed over 24 hours0.10.10.2-0.40.3-0.3-0.3-0.3-0.3-0.3-0.50.50.4-0.40.0
Number of responses in last shaping day0.60.81.20.9-1.11.01.00.90.80.90.7-0.8-0.90.8-0.5