Hub : Genes

Fabp4

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression Fabp4 0.17 0.1 2.3e-07 0.17 0.14 0.18 0.18 1.0e-07 1.3e-06 2.7e-08 2.2e-08
2 Adipose mRNA stability Fabp4 0.08 0.06 1.1e-08 0.05 0.04 0.03 0.04 1.9e-06 1.2e-05 3.4e-04 1.1e-05
3 NAcc gene expression Fabp4 0.12 0.07 2.3e-13 0.1 0.08 0.09 0.09 3.6e-11 6.7e-10 1.1e-10 1.9e-10
4 IL gene expression Fabp4 0.75 0.15 5.8e-07 0.08 0.06 0.06 0.12 6.7e-03 1.3e-02 1.9e-02 7.0e-04
5 PL gene expression Fabp4 0.43 0.15 0.0e+00 0.33 0.31 0.31 0.32 9.4e-37 9.4e-35 3.6e-35 2.8e-35
6 OFC gene expression Fabp4 0.36 0.18 2.5e-04 0.06 0.09 0.06 0.06 1.6e-02 3.6e-03 1.7e-02 2.0e-02
7 Brain gene expression Fabp4 0.19 0.11 1.5e-11 0.07 0.08 0.06 0.07 5.6e-07 1.5e-07 1.8e-06 5.7e-07
8 BLA gene expression Fabp4 0.43 0.17 0.0e+00 0.23 0.22 0.24 0.25 1.8e-12 4.4e-12 2.6e-13 1.9e-13
9 Adipose gene expression Fabp4 0.1 0.06 1.5e-06 0.06 0.05 0.05 0.05 6.7e-07 2.1e-06 2.5e-06 2.0e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density1.32.12.8-1.51.51.7-1.61.6-1.4-1.5-1.50.6
Area under the delay curve1.01.01.31.0-1.0-1.11.0-1.11.01.11.1-0.3
BMI with tail2.27.39.93.2-2.6-2.62.6-2.62.92.82.92.1
BMI without tail5.411.215.03.9-3.1-3.53.1-3.53.63.53.61.8
Body weight0.83.33.91.9-1.8-1.81.7-1.71.91.81.62.0
Weight adjusted by age0.20.20.50.7-0.2-0.50.2-0.40.40.40.60.1
Bone surface2.13.64.5-1.92.11.9-2.11.9-1.6-1.9-2.01.8
Bone volume1.93.34.0-1.61.92.0-2.01.9-1.5-1.8-1.81.7
Breakpoint value in progressive ratio session1.61.82.41.6-1.2-1.41.2-1.41.41.41.50.6
Number of licking bursts0.40.50.7-0.70.80.7-0.80.7-0.6-0.7-0.70.2
Context. condit. distance diff. score0.10.10.4-0.1-0.2-0.30.2-0.2-0.00.0-0.1-0.6
Locomotion velocity, session 12.72.93.81.8-1.9-1.81.9-1.81.71.81.70.5
Locomotion distance, session 11.31.71.91.4-1.4-1.21.3-1.31.41.31.21.3
Locomotion velocity, session 22.32.73.51.9-1.8-1.61.8-1.61.71.71.80.6
Locomotion distance, session 21.72.43.51.8-1.4-1.31.4-1.31.61.51.51.9
Locomotion velocity, session 30.00.00.1-0.0-0.10.00.1-0.0-0.0-0.0-0.1-0.3
Locomotion distance, session 30.10.20.3-0.20.30.4-0.40.4-0.3-0.4-0.40.6
Stereotopy head waving bouts, day 30.30.31.40.6-0.3-0.30.3-0.30.50.40.31.2
Stereotopy head waving duration, day 30.50.70.90.9-0.8-0.80.8-0.80.90.80.80.5
Locomotion velocity, session 73.74.04.7-2.01.92.2-2.02.2-1.7-2.0-2.12.0
Locomotion distance, session 73.94.96.6-2.62.22.4-2.22.4-2.2-2.3-2.40.4
Stereotopy head waving bouts, day 70.70.81.31.1-0.8-0.90.8-0.90.90.90.90.9
Stereotopy head waving duration, day 71.21.41.91.4-1.2-1.31.2-1.31.21.21.20.2
Locomotion velocity, session 83.94.65.72.4-2.3-2.42.3-2.42.22.22.10.2
Locomotion distance, session 81.21.72.21.4-1.4-1.51.4-1.51.41.31.10.7
Degree of sensitization distance0.40.40.7-0.80.60.6-0.60.6-0.6-0.6-0.6-0.0
Degree of sensitization stereotypy1.82.02.71.6-1.4-1.51.4-1.51.51.51.50.4
Conditioned locomotion0.20.20.30.5-0.5-0.50.5-0.40.50.50.50.2
Cocaine response after cond. corrected0.91.01.4-1.21.11.0-1.01.1-1.1-1.1-1.0-0.4
Cocaine response after cond. not corrected1.71.92.3-1.51.51.4-1.51.4-1.4-1.4-1.3-0.5
Cocaine response before conditioning0.20.20.4-0.40.60.5-0.70.4-0.4-0.5-0.40.3
Saline control response0.81.11.8-0.91.01.1-1.01.1-0.8-1.0-1.01.3
Bone: connectivity density1.62.53.7-1.91.61.7-1.61.6-1.6-1.7-1.80.2
Bone: cortical apparent density0.91.12.11.0-1.4-1.11.4-1.10.91.00.9-0.5
Bone: cortical area0.20.21.80.40.20.2-0.30.20.20.10.11.4
Bone: cortical porosity0.10.10.60.30.1-0.0-0.2-0.00.20.10.20.8
Bone: cortical porosity0.10.10.50.5-0.1-0.20.1-0.20.40.30.30.7
Bone: cortical thickness0.40.61.81.1-0.6-0.50.5-0.50.80.70.71.4
Bone: cortical thickness3.43.96.32.5-1.8-2.01.8-2.02.12.12.20.6
Bone: cortical tissue density0.91.22.21.0-1.5-1.11.5-1.10.91.01.0-0.5
Condit. Reinf. active minus inactive responses5.96.79.13.0-2.3-2.42.2-2.42.82.62.62.7
Condit. Reinf. active-inactive response ratio7.98.511.43.4-2.7-2.82.6-2.83.13.02.92.9
Condit. Reinf. active responses4.65.78.12.8-2.0-2.21.9-2.22.62.42.42.9
Condit. Reinf. inactive responses0.10.10.20.3-0.1-0.20.0-0.20.30.20.20.5
Incentive salience index mean6.17.410.03.2-2.5-2.62.4-2.62.92.72.72.9
Condit. Reinf. lever presses2.63.54.42.1-1.9-1.81.8-1.82.01.91.71.7
Condit. Reinf. active minus inactive responses1.92.44.6-1.21.61.5-1.71.5-1.1-1.4-1.42.1
Condit. Reinf. active-inactive response ratio1.01.03.3-0.71.00.9-1.10.9-0.6-0.8-0.81.8
Condit. Reinf. active responses2.63.65.0-1.62.12.0-2.22.0-1.5-1.8-1.82.2
Condit. Reinf. inactive responses0.20.30.3-0.40.50.6-0.60.5-0.4-0.5-0.60.6
Condit. Reinf. lever presses1.01.42.5-0.91.11.2-1.21.4-0.9-1.1-1.01.6
Condit. Reinf. lever reinforcers received2.94.15.3-1.72.22.1-2.32.1-1.6-1.9-1.92.2
Conditioned reinforcement - actives3.43.45.0-2.21.52.2-1.52.2-1.8-2.0-2.10.5
Conditioned reinforcement - inactives0.00.10.1-0.20.30.1-0.30.3-0.2-0.3-0.20.1
Conditioned locomotion1.92.33.3-1.81.11.8-1.11.8-1.5-1.6-1.70.7
Patch foraging indifference point 0 sec0.91.51.7-1.31.21.2-1.11.2-1.3-1.2-1.1-1.3
Patch foraging indifference point AUC0.50.61.01.0-0.7-0.80.7-0.70.70.70.8-0.7
Delay disc. indifference point, 0s delay0.10.10.1-0.3-0.00.30.00.3-0.2-0.2-0.3-0.3
Delay disc. indifference point, 16s delay1.01.01.31.1-1.0-1.11.0-1.11.01.11.1-0.3
Delay disc. indifference point, 2s delay0.91.02.41.1-0.9-0.80.9-0.81.00.90.71.6
Delay disc. indifference point, 24s delay0.10.10.20.1-0.1-0.30.1-0.30.20.20.4-0.5
Delay disc. indifference point, 4s delay1.81.92.31.5-1.3-1.51.4-1.51.41.41.5-0.3
Delay disc. indifference point, 8s delay0.20.21.20.00.0-0.3-0.0-0.20.00.10.4-1.1
Indifference point function ln k0.00.10.2-0.0-0.4-0.20.4-0.20.10.10.0-0.3
Indifference point function log k0.00.10.2-0.0-0.4-0.20.4-0.20.10.10.0-0.3
Patch foraging total patch changes 0 sec0.60.92.3-0.90.80.9-0.80.8-1.0-0.9-0.7-1.5
Patch foraging total patch changes 12 sec0.50.61.9-0.70.80.6-0.70.6-0.8-0.7-0.6-1.4
Patch foraging total patch changes 18 sec0.50.71.51.2-0.7-0.80.7-0.80.70.81.0-0.7
Patch foraging total patch changes 24 sec0.20.31.9-0.3-0.10.30.10.1-0.4-0.3-0.3-1.4
Patch foraging total patch changes 6 sec0.10.21.70.20.0-0.20.0-0.1-0.10.10.2-1.3
Patch foraging time to switch 0 sec1.82.85.01.9-1.4-1.61.3-1.61.81.61.52.2
Patch foraging water rate 0 sec0.30.42.3-0.60.30.4-0.20.3-0.5-0.4-0.4-1.5
Patch foraging water rate 12 sec1.52.32.8-1.71.61.6-1.61.6-1.6-1.6-1.5-0.9
Patch foraging water rate 18 sec0.60.71.1-1.10.81.0-0.80.9-0.9-0.9-0.9-0.1
Patch foraging water rate 24 sec0.20.31.6-0.5-0.00.30.10.3-0.4-0.2-0.3-1.3
Patch foraging water rate 6 sec2.23.24.3-2.11.81.9-1.81.9-1.9-1.9-1.9-0.8
Seeking ratio, delayed vs. immediate footshock9.310.713.8-3.73.53.3-3.53.3-3.4-3.4-3.4-1.3
Distance traveled before self-admin0.10.10.3-0.4-0.00.20.00.4-0.3-0.3-0.5-0.4
Distance traveled after self-admin0.20.21.1-0.40.30.1-0.30.3-0.4-0.3-0.3-1.0
Extensor digitorum longus weight10.842.449.47.0-6.9-6.96.9-7.06.86.86.52.6
Bone: elastic displacement0.30.42.60.5-0.1-0.30.0-0.20.40.30.31.6
Bone: elastic work0.30.32.70.20.20.0-0.20.10.20.10.11.7
Bone: endosteal estimation0.51.24.5-0.71.00.9-1.10.9-0.5-0.8-0.92.1
Bone: endosteal perimeter0.51.11.5-1.01.21.1-1.21.1-0.9-1.0-1.00.7
Epididymis fat weight0.10.21.8-0.2-0.40.10.40.0-0.2-0.1-0.1-1.3
Delta time in closed arm before/after self-admin0.20.20.5-0.60.20.5-0.10.3-0.5-0.4-0.5-0.7
Delta time in open arm before/after self-admin0.10.10.20.10.5-0.1-0.50.0-0.1-0.1-0.1-0.1
Diff in mean of infusions in LGA sessions2.42.73.92.0-1.5-1.61.4-1.81.71.61.61.4
Delay discount exponential model param0.70.71.0-0.90.81.0-0.81.0-0.9-0.9-1.00.3
Extinction: sum of active levers before priming1.01.01.61.3-0.9-1.00.9-1.11.01.11.20.0
Active lever presses in extinction session 60.30.30.5-0.60.50.7-0.50.5-0.6-0.6-0.6-0.1
Bone: final force0.20.32.20.50.0-0.1-0.1-0.10.40.30.31.5
Bone: final moment0.20.31.90.00.40.3-0.40.30.0-0.1-0.21.4
Food consumed during 24 hour testing period2.02.43.31.8-1.4-1.71.4-1.61.71.61.50.9
Glucose1.52.33.41.8-1.3-1.71.3-1.61.61.61.60.8
Heart weight1.82.53.9-2.01.41.7-1.41.6-1.7-1.7-1.7-1.1
Delay discount hyperbolic model param1.01.11.4-1.11.01.2-1.01.1-1.1-1.1-1.20.2
Intermittent access intake day 1-15 change5.65.57.3-2.72.32.5-2.32.5-2.5-2.4-2.3-1.6
Intermittent access intake escalation4.44.35.6-2.42.12.2-2.12.2-2.2-2.1-2.0-1.3
Intermittent access intake escalation 26.16.17.5-2.72.72.5-2.72.6-2.5-2.5-2.4-1.0
Intermitt. access day 1 inactive lever presses1.01.11.70.8-1.1-1.11.2-1.00.80.90.9-1.3
Intermitt. access day 15 inactive lever presses0.40.43.6-0.00.1-0.4-0.1-0.3-0.20.10.2-1.9
Intermitt. access escalation Index0.10.10.20.0-0.2-0.20.2-0.20.10.10.1-0.5
Intermittent access day 1 total infusions1.41.72.8-1.21.61.3-1.71.3-1.2-1.3-1.20.3
Intermittent access day 15 total infusions7.28.19.8-3.03.13.0-3.13.1-2.9-2.9-2.8-0.5
Intermittent access terminal intake (last 3 days)7.17.811.3-2.73.43.0-3.43.0-2.8-2.8-2.5-0.8
Intermittent access total infusions4.34.86.4-2.22.52.4-2.52.3-2.2-2.2-2.0-0.5
Intermittent access day 1 locomotion0.40.41.0-0.41.00.5-1.00.5-0.5-0.5-0.40.1
Intermittent access day 15 total locomotion0.70.71.4-0.71.10.9-1.20.9-0.8-0.8-0.70.4
Intermittent access total locomotion0.91.12.2-0.91.50.9-1.50.9-1.0-1.0-0.7-0.2
Intermittent access standard deviation5.45.88.2-2.92.32.4-2.22.4-2.5-2.4-2.3-2.2
Left kidney weight1.23.34.3-2.12.01.7-2.01.6-1.9-1.8-1.7-1.5
Right kidney weight0.61.83.9-1.41.41.1-1.31.0-1.3-1.2-1.1-2.0
Cocaine induced anxiety0.20.20.70.4-0.1-0.40.2-0.40.30.40.6-0.8
Post-drug Anxiety2.02.22.91.5-1.7-1.51.7-1.61.51.51.50.0
Baseline Anxiety0.20.20.80.3-0.5-0.50.4-0.50.40.30.10.9
Tail length0.51.42.21.3-1.1-1.51.1-1.41.21.21.10.3
Length with tail0.00.00.2-0.2-0.1-0.00.10.0-0.1-0.1-0.40.4
Length without tail0.71.62.7-1.60.91.4-0.91.4-1.2-1.4-1.60.4
Times rat made contact with spout0.10.10.2-0.20.50.2-0.50.2-0.3-0.3-0.2-0.1
Lifetime Intake4.24.76.3-2.32.52.3-2.52.3-2.2-2.2-2.0-0.7
Liver weight, left1.72.74.42.1-1.4-1.61.4-1.61.81.81.81.1
Liver weight, right0.20.30.60.7-0.4-0.50.4-0.50.50.60.8-0.6
Locomotor activity0.00.00.00.0-0.1-0.10.10.10.00.0-0.1-0.1
Locomotor testing distance0.00.00.00.1-0.1-0.10.10.10.0-0.0-0.10.2
Locomotor testing rearing0.81.31.5-1.21.21.1-1.21.1-1.2-1.2-1.2-0.7
Locomotion in novel chamber1.01.22.01.4-1.1-1.01.0-1.01.11.11.20.7
Locomotion in novel chamber post-restriction0.00.00.3-0.1-0.00.00.00.0-0.1-0.10.1-0.5
Fecal boli incidents, locomotor time 10.20.30.40.6-0.2-0.60.2-0.60.50.50.60.2
Change in fecal boli incidents, locomotor task2.62.53.4-1.81.51.7-1.51.7-1.6-1.6-1.8-0.3
Time >=10cm from walls, locomotor time 11.31.32.4-1.11.51.1-1.51.1-1.0-1.1-1.00.6
Bouts of movement, locomotor time 10.70.86.0-0.70.20.3-0.20.3-0.6-0.4-0.3-2.5
Total resting periods, locomotor time 10.60.64.1-0.70.30.4-0.20.4-0.6-0.4-0.4-2.0
Rest time, locomotor task time 10.50.62.3-0.80.30.6-0.30.6-0.7-0.6-0.7-1.5
Distance moved, locomotor task time 10.00.00.1-0.00.00.1-0.00.1-0.0-0.00.10.3
Vertical activity count, locomotor time 10.30.32.30.2-0.1-0.00.1-0.00.20.1-0.01.5
Time >=10cm from walls, locomotor time 20.60.71.6-0.61.00.6-1.00.7-0.5-0.7-0.71.3
Bouts of movement, locomotor time 20.60.64.50.0-0.4-0.40.4-0.40.10.30.4-2.1
Total resting periods, locomotor time 20.60.74.80.1-0.4-0.40.5-0.40.10.30.5-2.2
Rest time, locomotor task time 20.20.30.90.4-0.6-0.30.6-0.30.30.40.4-0.9
Distance moved, locomotor task time 20.00.00.1-0.20.20.2-0.20.3-0.2-0.2-0.0-0.3
Vertical activity count, locomotor time 20.91.01.31.2-1.0-0.90.9-0.91.11.00.91.1
Light reinforcement 10.91.62.41.5-1.2-1.31.3-1.31.11.31.5-0.8
Light reinforcement 22.63.54.62.1-1.8-2.01.8-2.01.92.02.10.2
Bone: marrow area0.51.04.6-0.60.90.8-1.00.8-0.4-0.7-0.82.2
Bone: maximum diameter0.20.30.7-0.30.80.7-0.80.6-0.5-0.5-0.40.3
Bone: maximum force0.20.42.80.40.20.0-0.30.10.30.10.21.7
Bone: maximum moment0.30.42.5-0.10.60.5-0.70.5-0.1-0.3-0.31.6
Mean time between licks in bursts1.11.53.01.4-1.1-1.11.1-1.01.31.21.01.7
Mean num. licks in bursts0.20.20.30.5-0.5-0.50.5-0.60.40.50.5-0.3
Cd content in liver1.01.11.90.8-1.0-1.11.0-1.10.81.01.0-1.4
Co content in liver0.30.31.40.1-0.6-0.50.7-0.50.20.30.2-1.2
Cu content in liver4.04.86.1-2.52.32.3-2.32.3-2.3-2.3-2.2-1.2
Fe content in liver0.50.64.3-0.10.40.4-0.50.4-0.1-0.3-0.42.1
K content in liver0.70.71.3-1.20.60.7-0.50.7-0.9-0.9-1.0-0.9
Mg content in liver0.40.40.7-0.80.50.7-0.50.7-0.7-0.7-0.8-0.1
Mn content in liver0.20.30.60.3-0.6-0.70.6-0.70.50.50.20.0
Na content in liver1.11.11.5-1.21.11.1-1.11.1-1.1-1.1-1.0-0.8
Rb content in liver0.00.00.20.1-0.1-0.00.2-0.00.00.10.2-0.5
Se content in liver0.10.20.4-0.50.40.2-0.30.2-0.5-0.4-0.5-0.6
Sr content in liver0.70.71.10.4-1.1-1.11.0-1.10.70.70.20.5
Zn content in liver1.51.72.7-1.61.21.2-1.21.2-1.4-1.4-1.4-1.0
Bone: minimum diameter1.01.912.51.3-0.4-0.50.3-0.51.10.80.73.5
Time in familiar zone, hab. session 10.80.82.2-1.00.40.7-0.40.7-0.9-0.8-0.9-1.5
Time in novel zone, hab. session 10.10.10.20.40.2-0.3-0.2-0.30.30.30.40.5
Total zone transitions, hab. session 11.21.72.01.4-1.4-1.21.4-1.21.31.31.21.1
Total locomotion distance, hab. session 10.50.72.40.9-0.8-0.60.7-0.60.80.70.61.5
Locomotion velocity, hab. session 11.01.42.91.3-1.1-0.91.1-1.01.21.01.01.7
Time in familiar zone, hab. session 22.32.45.1-1.71.11.4-1.01.4-1.6-1.5-1.5-2.3
Time in novel zone, hab. session 20.90.93.01.0-0.4-0.80.4-0.80.90.80.91.7
Total zone transitions, hab. session 20.40.50.90.6-0.9-0.61.0-0.70.60.60.6-0.4
Total locomotion distance, hab. session 20.20.30.50.7-0.5-0.40.5-0.40.50.50.50.6
Locomotion velocity, hab. session 20.10.20.30.6-0.4-0.30.4-0.30.40.40.40.5
Novel to familiar place preference ratio0.10.10.60.20.1-0.2-0.1-0.20.20.20.20.7
Novelty place preference0.00.00.20.00.3-0.1-0.3-0.00.10.00.10.4
Time in novel zone, NPP test0.00.00.10.10.3-0.1-0.3-0.10.10.10.10.2
Total zone transitions, NPP test0.91.22.01.1-1.4-1.21.4-1.11.11.11.00.0
Total locomotion distance, NPP test0.50.71.01.0-0.8-0.70.8-0.70.80.80.81.0
Locomotion velocity, NPP test0.20.31.20.7-0.5-0.40.4-0.40.60.50.51.1
Intraocular pressure2.53.44.22.0-1.9-1.91.9-1.81.91.91.71.4
Delta distance traveled before/after self-admin0.50.61.1-0.81.00.6-1.00.7-0.7-0.7-0.6-0.2
Delta ambulatory time before/after self-admin1.11.21.9-1.21.41.0-1.41.0-1.1-1.1-1.0-0.5
Parametrial fat weight0.20.40.70.5-0.8-0.80.9-0.80.60.60.5-0.4
Pavlov. Cond. lever latency0.70.91.2-1.10.90.9-0.90.9-1.0-0.9-0.8-1.0
Pavlov. Cond. magazine entry latency0.40.50.90.9-0.6-0.60.6-0.60.80.70.71.0
Pavlov. Cond. change in total contacts3.03.24.42.1-1.8-1.71.7-1.71.91.81.81.5
Pavlov. Cond. index score0.91.21.71.3-1.1-1.11.1-1.11.11.11.10.7
Pavlov. Cond. latency score0.81.11.61.3-1.1-1.01.1-1.11.11.01.00.6
Pavlov. Cond. lever contacts0.91.12.01.2-1.0-0.90.9-1.01.11.00.91.4
Pavlov. Cond. magazine entry number0.91.11.6-1.31.11.0-1.11.0-1.1-1.1-1.1-0.5
Pavlov. Cond. intertrial magazine entries0.50.60.8-0.80.70.8-0.80.8-0.8-0.8-0.90.1
Pavlov. Cond. lever-magazine prob. diff.0.91.11.61.3-1.1-1.01.1-1.11.11.11.00.7
Pavlov. Cond. response bias0.91.11.51.2-1.0-1.01.0-1.01.11.01.01.2
Pavlov. Cond. lever latency1.31.72.21.4-1.4-1.41.4-1.51.31.41.30.0
Pavlov. Cond. magazine entry latency0.00.00.10.10.20.1-0.20.1-0.0-0.00.10.3
Pavlov. Cond. change in total contacts0.40.54.10.00.40.2-0.40.30.0-0.2-0.32.0
Pavlov. Cond. index score0.30.41.6-0.20.60.5-0.60.6-0.3-0.4-0.41.3
Pavlov. Cond. latency score0.40.41.0-0.40.70.7-0.70.8-0.5-0.6-0.51.0
Pavlov. Cond. lever contacts0.81.11.6-1.01.11.2-1.11.2-1.0-1.1-1.00.3
Pavlov. Cond. magazine entry number0.10.10.6-0.2-0.00.10.10.0-0.2-0.1-0.1-0.7
Pavlov. Cond. intertrial magazine entries0.30.40.60.6-0.7-0.50.7-0.50.60.50.40.8
Pavlov. Cond. lever-magazine prob. diff.0.30.41.2-0.40.60.6-0.70.6-0.4-0.5-0.51.1
Pavlov. Cond. response bias0.40.61.2-0.50.80.8-0.90.9-0.5-0.7-0.61.1
Time in closed arm before self-admin0.40.50.8-0.90.70.6-0.70.7-0.8-0.7-0.7-0.5
Time in closed arm after self-admin0.60.61.4-1.00.40.7-0.30.7-0.8-0.7-0.7-1.2
Time in open arm before self-admin0.20.21.80.30.10.1-0.1-0.10.20.10.01.3
Time in open arm after self-admin1.11.22.41.6-0.8-1.20.8-1.21.21.21.10.7
Bone: periosteal estimation0.40.96.90.10.60.4-0.70.40.1-0.2-0.22.6
Bone: periosteal perimeter0.40.61.1-0.51.00.8-1.00.8-0.6-0.7-0.70.9
Bone: post-yield work3.24.45.4-2.32.32.2-2.32.2-2.1-2.2-2.1-0.4
Progressive ratio test 1 active lever presses3.23.34.4-1.92.11.6-2.01.6-1.9-1.7-1.5-1.9
Progressive ratio test 1 breakpoint3.03.24.7-1.82.21.7-2.11.6-1.8-1.6-1.4-1.7
Progressive ratio test 1 inactive lever presses0.10.10.7-0.20.40.0-0.30.2-0.3-0.2-0.1-0.8
Progressive ratio test 2 active lever presses3.03.24.0-1.92.01.9-2.01.8-1.8-1.9-1.8-0.4
Progressive ratio test 2 breakpoint2.62.93.6-1.91.91.8-1.91.8-1.7-1.8-1.7-0.1
Progressive ratio test 2 inactive lever presses1.72.02.8-1.41.71.5-1.71.4-1.4-1.4-1.3-0.4
Incentive Sensitization - Responses1.41.41.8-1.11.11.3-1.21.2-1.1-1.2-1.21.0
Incentive Sensitization - Breakpoint1.41.41.9-1.21.11.4-1.21.3-1.1-1.3-1.30.8
Sum of active levers in priming session hrs 5-60.10.10.5-0.30.10.5-0.20.4-0.2-0.3-0.30.7
Progressive ratio1.31.53.6-1.41.21.0-1.21.0-1.2-1.0-0.8-1.9
Food seeking constrained by brief footshock3.44.25.72.4-2.0-1.91.9-1.92.22.02.02.0
Seeking ratio, punishment vs. effort4.25.27.32.6-2.4-2.02.3-2.02.32.11.92.7
Retroperitoneal fat weight0.00.10.3-0.50.20.3-0.10.3-0.3-0.3-0.3-0.4
Reaction time number correct0.30.51.7-0.40.60.6-0.70.6-0.4-0.5-0.61.3
Reaction time mean minus median2.53.34.62.0-1.7-2.01.7-1.91.71.92.2-0.9
Reaction time mean minus median AUC3.24.26.02.4-1.8-2.31.8-2.22.12.22.4-0.4
Reaction time num false alarms1.01.42.7-1.01.31.1-1.41.1-0.8-1.0-1.01.6
Reaction time num false alarms AUC0.91.31.9-1.01.31.1-1.31.1-0.9-1.0-1.01.4
Reaction time trials correct on left0.30.51.7-0.40.60.6-0.70.6-0.4-0.5-0.61.3
Reaction time trials on left0.30.41.8-0.20.50.5-0.60.5-0.3-0.4-0.51.3
Reaction time mean2.23.04.32.1-1.7-1.81.7-1.81.81.82.10.2
Reaction time mean AUC2.53.34.92.2-1.7-1.91.7-1.91.91.92.20.5
Median of all reaction times1.92.73.82.0-1.7-1.61.6-1.51.71.71.90.8
Reaction time omissions4.35.88.62.9-2.3-2.52.3-2.52.52.62.8-0.1
Reaction time false alarm rate0.20.30.4-0.60.60.5-0.60.5-0.5-0.5-0.50.1
Reaction time premature initiation rate1.92.54.0-2.01.51.4-1.41.5-1.7-1.6-1.5-1.5
Reaction time premature initiations1.82.53.8-1.91.61.5-1.61.6-1.7-1.7-1.6-0.8
Std. dev. reaction times1.72.33.51.8-1.4-1.71.4-1.61.51.61.9-0.8
Reaction time trials completed0.30.41.8-0.20.50.5-0.60.5-0.3-0.4-0.51.3
Reaction time trials AUC0.20.32.1-0.10.40.4-0.50.4-0.2-0.3-0.41.4
Run reversals in cocaine runway, females0.80.81.20.8-1.1-0.91.1-0.90.90.90.9-0.0
Run reversals in cocaine runway, males3.43.34.52.1-1.8-1.81.8-1.81.91.91.81.1
Latency to leave start box in cocaine runway0.80.81.2-1.10.90.9-0.90.9-0.9-1.0-1.0-0.3
Latency to leave start box in cocaine runway, F3.33.65.1-2.31.91.9-1.91.9-2.0-2.0-2.1-0.6
Latency to leave start box in cocaine runway, M2.32.22.91.7-1.6-1.61.5-1.61.51.61.50.5
Std. dev. time between licks in bursts0.10.10.7-0.0-0.10.10.10.20.1-0.0-0.20.8
Total sessions with >9 infusions1.01.11.7-1.01.30.9-1.30.9-1.1-1.0-0.7-1.3
Short access day 1 total inactive lever presses0.40.51.1-0.60.80.5-0.80.5-0.7-0.6-0.5-1.0
Short access day 10 total inactive lever presses0.20.31.5-0.0-0.5-0.30.6-0.30.10.20.1-1.2
Short access day 1 total infusions2.22.32.7-1.61.51.6-1.51.6-1.6-1.5-1.4-1.3
Short access day 10 total infusions2.73.04.0-1.92.01.6-2.01.6-1.8-1.7-1.6-1.2
Short access total infusions2.93.34.7-1.92.21.8-2.21.8-1.9-1.8-1.6-1.0
Short access day 1 locomotion0.30.30.7-0.30.70.4-0.70.4-0.5-0.3-0.0-0.9
Short access day 10 total locomotion1.01.11.51.2-0.9-1.20.9-1.21.01.11.2-0.5
Short access total locomotion0.40.51.1-0.51.10.6-1.00.5-0.6-0.6-0.3-0.5
One hour access (0.3 mA shock)5.15.97.9-2.82.42.7-2.42.7-2.5-2.6-2.6-0.1
Compulsive drug intake1.61.63.51.1-1.9-1.21.9-1.31.21.10.80.2
One hour access (shock baseline)8.19.412.2-3.33.53.3-3.53.3-3.1-3.1-2.9-0.7
Social response proportion0.20.20.40.6-0.3-0.60.3-0.50.40.40.5-0.5
Social responses0.60.81.21.1-0.7-0.90.7-1.00.80.91.0-0.7
Social time0.00.10.20.20.5-0.0-0.50.1-0.0-0.10.10.3
Soleus weight0.92.53.51.9-1.5-1.61.5-1.71.71.71.70.7
Bone: stiffness0.10.10.50.30.1-0.1-0.1-0.10.20.20.20.7
Tibialis anterior weight8.529.036.66.1-5.5-5.65.4-5.65.75.65.43.2
Time to tail flick, vehicle, before self-admin0.80.91.4-1.10.51.2-0.51.2-0.9-1.0-1.10.5
Time to tail flick, vehicle, after self-admin2.32.43.7-1.91.51.6-1.51.7-1.6-1.7-1.80.1
Time to tail flick, test, before self-admin0.20.22.0-0.1-0.1-0.00.1-0.1-0.2-0.0-0.1-1.4
Time to tail flick, test, after self-admin0.80.81.4-0.81.20.8-1.10.9-0.9-0.9-0.7-0.8
Delta time to tail flick, vehicle, before/after SA1.11.11.5-1.21.21.0-1.21.0-1.0-1.1-1.1-0.0
Delta time to tail flick, test, before/after SA0.10.10.2-0.10.30.0-0.30.1-0.2-0.10.1-0.5
Tibia length1.44.15.5-2.32.12.1-2.02.2-2.1-2.1-2.0-0.8
Ambulatory time before self-admin0.10.10.2-0.3-0.20.10.20.3-0.2-0.2-0.3-0.4
Ambulatory time after self-admin0.40.50.7-0.80.80.4-0.80.6-0.7-0.7-0.7-0.6
Bone: tissue strength2.82.73.9-1.92.01.5-2.01.5-1.7-1.6-1.5-1.0
Total heroin consumption0.20.20.60.5-0.2-0.30.2-0.40.40.40.30.8
Bone: trabecular number0.81.21.7-1.21.11.3-1.11.2-1.1-1.1-1.10.1
Bone: trabecular spacing1.21.51.81.3-1.3-1.31.3-1.31.21.31.4-0.4
Bone: trabecular thickness1.82.12.9-1.41.41.7-1.51.7-1.3-1.5-1.50.9
Bone: trabecular tissue density2.33.24.72.2-1.7-1.91.7-1.91.71.92.1-0.5
Water consumed over 24 hours0.10.10.20.5-0.2-0.40.2-0.40.40.40.30.2
Number of responses in last shaping day0.10.10.4-0.00.30.1-0.30.1-0.2-0.10.1-0.7