Hub : Genes

Cfap206

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc alternative TSS NM_001079701.1 0.06 0.04 2.4e-06 0.04 0.05 0.05 0.04 3.5e-05 1.0e-06 6.7e-07 7.0e-06
2 BLA gene expression Cfap206 0.74 0.09 0.0e+00 0.59 0.66 0.67 0.66 1.7e-38 4.6e-46 3.5e-47 4.3e-46
3 Brain intron excision ratio chr5_49298069_49298912 0.03 0.03 8.2e-03 0.02 0.02 0.03 0.02 5.2e-03 1.0e-02 1.6e-03 1.1e-02
4 Brain intron excision ratio chr5_49298069_49298969 0.03 0.03 8.5e-03 0.02 0.02 0.03 0.02 5.3e-03 9.7e-03 1.1e-03 9.0e-03
5 Brain gene expression Cfap206 0.55 0.1 0.0e+00 0.59 0.61 0.61 0.6 2.6e-68 1.1e-71 9.6e-71 1.9e-70
6 PL gene expression Cfap206 0.29 0.12 0.0e+00 0.31 0.34 0.34 0.33 1.2e-34 7.6e-39 2.4e-38 1.5e-37
7 pVTA gene expression Cfap206 0.6 0.14 0.0e+00 0.59 0.61 0.62 0.61 6.6e-31 4.5e-33 2.5e-33 1.3e-32
8 RMTg gene expression Cfap206 0.59 0.2 4.1e-14 0.48 0.45 0.47 0.47 8.2e-15 2.2e-13 2.8e-14 2.9e-14
9 LHb gene expression Cfap206 0.71 0.14 6.4e-15 0.4 0.4 0.38 0.4 1.6e-10 1.9e-10 4.6e-10 1.2e-10
10 NAcc gene expression Cfap206 0.87 0.03 0.0e+00 0.5 0.58 0.55 0.56 9.9e-67 5.2e-83 1.7e-76 2.4e-78
11 IL gene expression Cfap206 0.44 0.21 1.3e-06 0.22 0.21 0.2 0.2 5.8e-06 7.9e-06 1.2e-05 1.2e-05
12 Brain isoform ratio XM_017593532.2 0.03 0.02 3.7e-03 0 0.02 0.01 0.01 9.1e-02 4.8e-03 1.5e-02 2.3e-02
13 NAcc isoform ratio XM_017593532.2 0.07 0.04 4.7e-08 0.07 0.07 0.06 0.07 3.4e-08 1.5e-08 5.5e-08 3.2e-08
14 NAcc alternative TSS NM_001079701.1 0.06 0.04 1.9e-06 0.05 0.05 0.05 0.04 4.1e-06 7.2e-07 1.1e-06 7.3e-06
15 BLA isoform ratio XM_017593532.2 0.11 0.09 1.1e-04 0.03 0.07 0.18 0.11 9.3e-03 1.5e-04 4.5e-10 1.5e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Bone: apparent density0.40.81.8-0.70.91.2-1.2-0.9-0.90.90.9-0.7-0.90.9-1.3-0.40.10.5
Area under the delay curve0.00.00.1-0.00.00.3-0.30.10.0-0.1-0.00.0-0.1-0.10.0-0.00.0-0.1
BMI with tail2.99.416.1-3.93.31.2-1.2-3.2-3.13.23.2-3.7-3.83.2-1.4-3.94.00.9
BMI without tail2.55.26.4-2.42.52.3-2.3-2.5-2.52.52.2-2.5-2.42.3-2.4-2.01.71.1
Body weight5.723.829.6-5.45.34.5-4.5-5.1-5.25.35.1-5.4-5.35.2-4.0-5.14.81.7
Weight adjusted by age2.52.84.4-1.61.82.1-2.1-1.7-1.71.71.7-1.7-1.81.7-1.8-1.31.10.9
Bone surface1.52.75.9-1.31.72.1-2.2-1.7-1.81.71.5-1.4-1.61.7-2.4-0.80.30.8
Bone volume0.71.13.5-0.71.01.5-1.5-1.1-1.11.00.9-0.7-1.11.0-1.9-0.2-0.20.5
Breakpoint value in progressive ratio session0.10.10.60.2-0.10.3-0.3-0.2-0.20.10.20.1-0.20.1-0.80.4-0.60.3
Number of licking bursts0.10.10.40.4-0.1-0.10.10.50.4-0.4-0.60.30.3-0.20.10.5-0.50.3
Context. condit. distance diff. score0.80.91.40.9-0.9-1.21.21.01.0-1.0-1.10.70.9-1.11.20.7-0.5-0.7
Locomotion velocity, session 10.10.10.40.2-0.4-0.40.40.30.4-0.4-0.20.10.1-0.20.60.10.1-0.5
Locomotion distance, session 13.34.36.12.4-2.2-1.51.52.52.4-2.4-2.22.02.3-2.42.12.1-1.80.0
Locomotion velocity, session 20.10.10.3-0.10.00.0-0.10.20.1-0.10.1-0.20.1-0.10.6-0.30.50.2
Locomotion distance, session 24.76.510.12.6-2.8-2.82.82.92.9-2.9-2.82.42.6-2.63.22.0-1.5-0.2
Locomotion velocity, session 32.12.44.71.3-1.6-1.91.91.71.7-1.7-1.71.41.5-1.62.20.9-0.5-0.9
Locomotion distance, session 32.93.16.91.5-1.8-2.32.21.91.9-1.9-1.91.51.6-1.92.60.9-0.4-0.9
Stereotopy head waving bouts, day 30.70.81.7-0.60.81.2-1.3-0.9-1.00.91.0-0.8-0.80.8-1.3-0.50.20.4
Stereotopy head waving duration, day 31.72.02.7-1.51.51.3-1.3-1.5-1.51.51.6-1.6-1.41.5-1.3-1.41.20.7
Locomotion velocity, session 70.50.62.40.4-0.6-1.01.00.90.8-0.7-0.70.20.8-0.61.60.00.3-0.1
Locomotion distance, session 71.51.84.41.2-1.3-1.61.61.61.6-1.5-1.61.01.4-1.22.10.7-0.4-0.4
Stereotopy head waving bouts, day 70.70.82.8-1.20.7-0.00.0-0.7-0.70.70.7-1.1-0.70.90.3-1.41.7-0.1
Stereotopy head waving duration, day 71.92.34.6-2.01.50.6-0.6-1.6-1.51.61.7-1.9-1.61.6-0.6-2.02.2-0.0
Locomotion velocity, session 84.04.810.71.7-2.3-2.72.72.42.4-2.3-2.31.72.1-2.33.31.1-0.5-1.2
Locomotion distance, session 86.18.913.13.0-3.1-3.23.23.33.3-3.3-3.32.83.1-3.23.62.4-1.8-1.1
Degree of sensitization distance0.40.40.6-0.80.70.6-0.6-0.6-0.60.70.7-0.8-0.50.8-0.4-0.70.70.1
Degree of sensitization stereotypy0.80.83.6-1.30.6-0.60.6-0.6-0.50.60.6-1.0-0.70.70.8-1.51.9-0.2
Conditioned locomotion0.10.10.50.10.30.7-0.7-0.2-0.20.20.3-0.00.10.1-0.60.1-0.30.6
Cocaine response after cond. corrected0.80.91.3-0.91.01.1-1.1-0.9-1.01.00.7-1.0-1.01.1-0.9-0.80.70.7
Cocaine response after cond. not corrected0.40.41.3-0.50.71.1-1.1-0.5-0.60.60.2-0.6-0.40.5-0.5-0.40.40.7
Cocaine response before conditioning0.10.10.40.3-0.20.1-0.10.40.3-0.3-0.30.20.5-0.70.50.2-0.10.2
Saline control response1.52.04.8-1.11.32.2-2.2-1.4-1.51.41.2-1.0-1.31.4-1.8-0.80.50.5
Bone: connectivity density0.81.32.2-1.11.21.3-1.3-1.2-1.31.31.3-1.1-1.01.3-1.5-0.80.60.4
Bone: cortical apparent density0.10.10.40.3-0.1-0.40.40.40.3-0.3-0.60.20.2-0.30.00.6-0.70.2
Bone: cortical area3.65.47.9-2.42.62.8-2.8-2.4-2.52.42.3-2.4-2.32.0-2.4-2.11.71.3
Bone: cortical porosity0.40.41.50.40.11.2-1.2-0.2-0.20.10.20.40.1-0.3-1.10.6-0.90.2
Bone: cortical porosity0.70.82.8-0.40.81.7-1.7-0.8-0.80.80.8-0.5-0.50.3-1.2-0.30.00.5
Bone: cortical thickness0.91.62.9-1.21.51.7-1.7-1.2-1.31.21.0-1.3-1.10.8-1.2-1.00.81.1
Bone: cortical thickness0.40.51.2-1.00.90.5-0.5-0.6-0.60.60.5-0.9-0.80.40.0-1.01.10.5
Bone: cortical tissue density0.10.10.40.3-0.1-0.30.30.40.3-0.3-0.50.20.2-0.3-0.00.6-0.70.2
Condit. Reinf. active minus inactive responses2.42.73.71.5-1.9-1.91.91.81.8-1.8-1.61.51.6-1.71.91.3-1.0-1.2
Condit. Reinf. active-inactive response ratio0.70.71.00.7-1.0-0.90.90.90.9-0.9-0.80.90.9-0.90.80.8-0.7-0.9
Condit. Reinf. active responses1.51.83.11.2-1.4-1.61.61.51.5-1.4-1.31.11.4-1.41.80.9-0.6-0.7
Condit. Reinf. inactive responses0.60.71.50.8-0.7-1.11.10.90.9-0.9-0.70.60.9-0.91.20.5-0.20.2
Incentive salience index mean0.81.01.71.0-1.1-1.21.21.21.1-1.1-0.90.81.1-1.01.30.7-0.5-0.6
Condit. Reinf. lever presses0.10.10.40.00.2-0.20.20.20.2-0.1-0.0-0.50.10.00.6-0.30.40.3
Condit. Reinf. active minus inactive responses0.60.71.4-0.91.01.2-1.2-0.5-0.60.70.8-1.0-0.80.6-0.1-1.01.00.1
Condit. Reinf. active-inactive response ratio0.40.41.8-0.80.50.0-0.0-0.1-0.20.30.3-0.9-0.50.40.9-1.01.4-0.2
Condit. Reinf. active responses0.81.14.0-0.81.22.0-2.0-0.7-0.90.91.0-0.9-0.70.6-0.9-0.70.50.7
Condit. Reinf. inactive responses0.70.83.8-0.20.71.9-1.9-0.5-0.70.60.7-0.3-0.30.2-1.30.0-0.40.8
Condit. Reinf. lever presses1.41.93.2-1.51.51.8-1.8-1.2-1.31.31.6-1.6-1.21.0-0.9-1.41.30.3
Condit. Reinf. lever reinforcers received1.21.74.8-1.11.42.2-2.2-1.0-1.21.11.3-1.2-1.00.8-1.1-0.90.80.9
Conditioned reinforcement - actives0.20.20.8-0.50.4-0.10.1-0.4-0.40.50.6-0.5-0.70.30.1-0.80.90.0
Conditioned reinforcement - inactives0.10.10.50.1-0.00.7-0.70.40.2-0.1-0.10.0-0.1-0.40.4-0.10.20.3
Conditioned locomotion0.40.50.8-0.80.60.1-0.1-0.9-0.80.80.8-0.7-0.60.9-0.5-0.90.90.3
Patch foraging indifference point 0 sec0.20.30.5-0.40.50.7-0.7-0.6-0.60.50.7-0.3-0.30.2-0.7-0.30.20.4
Patch foraging indifference point AUC1.61.82.5-1.51.51.1-1.1-1.5-1.51.51.3-1.6-1.61.4-1.2-1.41.20.7
Delay disc. indifference point, 0s delay0.20.20.50.3-0.4-0.30.40.50.5-0.5-0.60.40.2-0.50.70.2-0.0-0.6
Delay disc. indifference point, 16s delay0.20.21.0-0.30.51.0-1.0-0.1-0.20.20.2-0.3-0.30.1-0.2-0.20.20.5
Delay disc. indifference point, 2s delay0.10.10.3-0.40.40.5-0.5-0.4-0.40.40.1-0.2-0.50.2-0.5-0.20.10.1
Delay disc. indifference point, 24s delay0.00.00.1-0.30.20.1-0.10.0-0.10.0-0.2-0.1-0.3-0.1-0.0-0.10.10.1
Delay disc. indifference point, 4s delay0.30.30.50.7-0.7-0.30.30.60.6-0.6-0.50.60.6-0.50.60.4-0.3-0.7
Delay disc. indifference point, 8s delay0.00.00.20.3-0.20.1-0.10.20.2-0.20.10.30.2-0.10.00.2-0.2-0.4
Indifference point function ln k0.50.70.90.9-0.9-0.90.90.90.9-0.9-0.50.90.8-0.80.90.6-0.5-0.5
Indifference point function log k0.50.70.90.9-0.9-0.90.90.90.9-0.9-0.50.90.8-0.80.90.6-0.5-0.5
Patch foraging total patch changes 0 sec0.10.20.4-0.40.40.7-0.6-0.5-0.50.40.6-0.4-0.30.2-0.5-0.40.30.2
Patch foraging total patch changes 12 sec1.41.83.6-1.71.40.7-0.7-1.4-1.41.41.6-1.6-1.21.3-0.5-1.81.90.0
Patch foraging total patch changes 18 sec0.40.50.8-0.90.80.9-0.9-0.7-0.70.70.5-0.7-0.60.3-0.7-0.60.50.3
Patch foraging total patch changes 24 sec1.62.04.0-1.41.42.0-2.0-1.5-1.51.41.4-1.3-1.21.3-1.6-1.10.90.5
Patch foraging total patch changes 6 sec0.50.71.3-0.80.81.1-1.1-0.9-0.90.90.9-0.7-0.90.6-1.0-0.60.50.3
Patch foraging time to switch 0 sec1.72.63.71.8-1.8-1.41.31.81.7-1.7-1.71.91.9-1.51.31.8-1.7-0.8
Patch foraging water rate 0 sec1.42.33.1-1.61.61.7-1.7-1.6-1.61.61.6-1.6-1.61.3-1.3-1.61.40.6
Patch foraging water rate 12 sec0.50.73.0-0.80.91.7-1.7-0.5-0.70.60.4-0.7-0.70.1-0.3-0.80.80.4
Patch foraging water rate 18 sec0.40.52.3-1.10.70.3-0.3-0.3-0.40.50.3-0.9-0.40.10.7-1.21.50.3
Patch foraging water rate 24 sec0.30.41.3-0.50.0-0.90.80.20.1-0.10.1-0.4-0.3-0.41.1-0.81.1-0.6
Patch foraging water rate 6 sec0.71.12.0-1.31.11.2-1.2-0.8-0.90.90.8-1.3-1.10.6-0.2-1.31.40.5
Seeking ratio, delayed vs. immediate footshock0.00.00.20.1-0.00.2-0.2-0.0-0.00.00.40.00.20.0-0.30.2-0.3-0.1
Distance traveled before self-admin0.50.51.6-0.70.2-0.70.7-0.6-0.50.50.7-0.4-0.60.60.3-1.11.3-0.9
Distance traveled after self-admin0.10.10.6-0.2-0.10.0-0.00.20.1-0.1-0.2-0.0-0.3-0.20.5-0.30.5-0.7
Extensor digitorum longus weight4.015.819.8-4.44.54.1-4.1-4.0-4.24.24.1-4.4-4.04.2-3.4-3.93.61.5
Bone: elastic displacement0.20.20.80.7-0.4-0.00.00.30.3-0.3-0.50.50.4-0.4-0.30.7-0.90.3
Bone: elastic work1.41.83.5-1.11.41.6-1.6-1.5-1.51.51.4-1.1-1.21.3-1.9-0.80.50.8
Bone: endosteal estimation4.08.711.3-3.43.12.9-2.9-3.3-3.23.23.3-3.1-3.02.9-2.7-3.02.80.8
Bone: endosteal perimeter2.75.67.5-2.52.42.4-2.4-2.7-2.62.62.7-2.3-2.42.3-2.5-2.21.90.6
Epididymis fat weight0.20.42.00.7-0.50.2-0.20.00.1-0.2-0.20.60.3-0.1-1.01.1-1.40.1
Delta time in closed arm before/after self-admin0.20.20.40.3-0.4-0.70.70.30.4-0.4-0.30.40.3-0.40.20.5-0.5-0.1
Delta time in open arm before/after self-admin0.10.10.4-0.30.1-0.00.0-0.0-0.10.10.2-0.3-0.10.10.4-0.50.6-0.2
Diff in mean of infusions in LGA sessions0.40.41.20.9-0.9-0.30.30.50.6-0.7-0.50.70.5-0.7-0.01.0-1.1-0.1
Delay discount exponential model param0.00.00.0-0.10.1-0.20.2-0.1-0.10.20.1-0.10.00.2-0.1-0.10.10.2
Extinction: sum of active levers before priming0.60.61.30.5-0.7-0.90.90.80.8-0.8-0.60.50.6-0.71.10.3-0.1-1.0
Active lever presses in extinction session 60.70.71.61.1-0.90.2-0.20.70.7-0.8-0.91.00.7-0.80.01.2-1.3-0.3
Bone: final force2.54.05.3-2.22.02.2-2.2-2.3-2.32.22.3-1.8-1.91.9-2.2-1.81.60.3
Bone: final moment3.25.36.8-2.52.32.6-2.6-2.6-2.62.52.6-2.1-2.22.1-2.5-2.11.70.3
Food consumed during 24 hour testing period1.82.13.2-1.61.51.8-1.8-1.4-1.61.51.3-1.5-1.41.6-1.4-1.31.2-0.2
Glucose0.00.00.1-0.20.20.00.0-0.2-0.20.20.0-0.1-0.10.3-0.2-0.20.2-0.1
Heart weight0.81.12.0-1.11.21.4-1.4-1.1-1.11.20.8-1.0-1.11.0-1.1-1.00.80.2
Delay discount hyperbolic model param0.00.00.1-0.10.1-0.10.1-0.1-0.10.20.1-0.10.00.2-0.1-0.10.00.2
Intermittent access intake day 1-15 change3.43.45.32.0-2.1-1.41.42.12.0-2.0-1.81.92.3-1.82.01.5-1.3-1.4
Intermittent access intake escalation2.72.74.61.8-1.9-1.11.11.91.8-1.8-1.61.72.1-1.61.81.4-1.2-1.3
Intermittent access intake escalation 21.31.32.81.2-1.3-0.90.91.41.3-1.2-0.91.01.7-1.01.50.8-0.5-1.0
Intermitt. access day 1 inactive lever presses0.50.51.60.3-0.4-0.80.80.80.7-0.7-1.30.50.1-1.10.90.5-0.30.4
Intermitt. access day 15 inactive lever presses1.92.13.31.6-1.50.2-0.21.81.6-1.6-1.81.61.5-1.81.11.6-1.6-0.4
Intermitt. access escalation Index0.10.10.50.1-0.1-0.70.70.00.2-0.20.10.20.2-0.1-0.10.3-0.3-0.3
Intermittent access day 1 total infusions2.02.33.0-1.51.71.7-1.6-1.6-1.71.61.4-1.5-1.61.7-1.5-1.41.21.0
Intermittent access day 15 total infusions0.10.10.3-0.30.30.4-0.4-0.2-0.30.30.3-0.3-0.00.5-0.0-0.50.50.0
Intermittent access terminal intake (last 3 days)0.10.10.40.10.10.6-0.60.10.0-0.0-0.00.00.40.20.1-0.00.10.1
Intermittent access total infusions1.41.52.3-1.21.31.5-1.5-1.1-1.21.31.2-1.3-0.81.5-0.9-1.31.20.6
Intermittent access day 1 locomotion0.30.31.2-0.20.50.5-0.5-0.7-0.60.60.3-0.1-0.60.5-1.1-0.0-0.20.8
Intermittent access day 15 total locomotion0.10.10.50.20.20.4-0.4-0.4-0.40.30.30.1-0.20.3-0.70.1-0.20.6
Intermittent access total locomotion0.40.51.2-0.40.70.7-0.7-0.9-0.80.80.7-0.5-0.70.8-1.1-0.40.20.7
Intermittent access standard deviation1.21.32.91.2-1.4-0.60.61.41.3-1.2-1.11.11.5-1.01.70.7-0.4-1.1
Left kidney weight2.98.011.0-3.33.22.6-2.6-3.0-3.03.12.7-3.2-3.02.8-2.3-3.02.71.5
Right kidney weight2.77.610.1-3.23.12.7-2.7-2.8-2.93.02.8-3.1-2.82.8-2.2-2.92.71.3
Cocaine induced anxiety0.20.20.90.5-0.6-0.90.90.10.2-0.3-0.10.50.1-0.20.30.2-0.1-0.4
Post-drug Anxiety0.10.10.3-0.0-0.1-0.60.6-0.5-0.30.20.30.1-0.40.2-0.3-0.20.1-0.2
Baseline Anxiety0.10.10.5-0.10.30.7-0.7-0.0-0.10.20.1-0.2-0.10.0-0.3-0.0-0.00.1
Tail length1.03.09.6-1.01.63.1-3.1-1.6-1.71.71.3-1.3-1.01.3-2.7-0.60.01.0
Length with tail2.48.916.1-2.73.14.0-4.0-3.1-3.23.22.9-2.8-2.73.0-3.5-2.31.71.4
Length without tail1.73.75.6-2.21.91.5-1.5-2.0-2.02.02.1-1.9-2.12.1-1.2-2.42.30.2
Times rat made contact with spout0.20.21.10.10.21.0-1.0-0.1-0.20.2-0.1-0.1-0.10.4-0.60.2-0.40.0
Lifetime Intake1.31.52.6-1.21.31.6-1.6-1.1-1.21.21.2-1.3-0.91.4-0.8-1.31.20.6
Liver weight, left0.71.03.60.70.11.8-1.8-0.0-0.10.0-0.30.50.2-0.2-1.71.3-1.90.2
Liver weight, right0.30.41.30.50.11.1-1.10.20.1-0.1-0.50.1-0.10.0-0.80.8-1.10.9
Locomotor activity0.71.01.91.1-1.3-1.11.10.70.9-1.0-1.21.40.8-1.00.70.9-0.8-1.0
Locomotor testing distance0.40.61.10.8-0.9-1.01.00.50.6-0.7-1.01.00.4-0.80.40.7-0.7-0.5
Locomotor testing rearing0.81.22.00.9-1.3-1.41.40.91.0-1.0-1.31.20.8-1.31.00.8-0.7-0.6
Locomotion in novel chamber0.60.71.8-0.80.90.1-0.1-1.1-1.01.01.4-0.9-0.71.1-1.1-0.70.50.7
Locomotion in novel chamber post-restriction0.70.81.61.2-1.0-0.70.70.80.8-0.9-0.51.10.9-0.90.21.2-1.3-0.7
Fecal boli incidents, locomotor time 10.10.10.50.10.10.7-0.7-0.2-0.20.20.0-0.00.40.4-0.60.3-0.5-0.0
Change in fecal boli incidents, locomotor task0.20.20.70.6-0.30.0-0.00.30.3-0.4-0.20.5-0.1-0.5-0.20.7-0.80.4
Time >=10cm from walls, locomotor time 10.20.21.6-0.10.31.3-1.30.1-0.10.10.2-0.20.10.1-0.0-0.20.20.0
Bouts of movement, locomotor time 10.30.30.60.6-0.6-0.70.70.60.6-0.6-0.50.60.8-0.50.50.6-0.6-0.4
Total resting periods, locomotor time 10.10.10.50.4-0.3-0.00.00.30.3-0.3-0.30.40.5-0.2-0.10.6-0.7-0.2
Rest time, locomotor task time 10.50.62.00.7-0.8-0.50.50.80.8-0.7-0.80.81.4-0.40.50.9-0.9-0.3
Distance moved, locomotor task time 10.50.51.2-0.70.5-0.70.7-0.8-0.60.60.9-0.7-1.00.5-0.1-1.01.1-0.1
Vertical activity count, locomotor time 10.20.30.9-0.20.2-1.01.0-0.3-0.20.20.2-0.3-0.60.10.4-0.60.8-0.2
Time >=10cm from walls, locomotor time 21.81.94.5-1.31.52.1-2.1-1.2-1.41.41.2-1.3-1.21.4-1.3-1.10.90.4
Bouts of movement, locomotor time 20.00.00.1-0.00.30.3-0.30.0-0.10.1-0.0-0.2-0.20.1-0.1-0.00.00.1
Total resting periods, locomotor time 20.00.00.00.10.20.0-0.00.0-0.00.0-0.1-0.1-0.10.1-0.10.0-0.10.1
Rest time, locomotor task time 20.60.71.71.0-0.9-0.80.80.80.8-0.8-0.40.91.3-0.50.41.0-1.0-0.0
Distance moved, locomotor task time 20.40.51.3-0.5-0.0-1.11.1-0.2-0.10.10.2-0.3-0.7-0.10.8-0.81.1-1.0
Vertical activity count, locomotor time 20.70.82.6-1.10.7-0.30.3-0.8-0.80.80.6-1.0-1.30.60.2-1.41.6-0.6
Light reinforcement 11.73.16.3-2.32.00.6-0.6-1.8-1.71.91.6-2.2-1.61.9-0.6-2.42.50.6
Light reinforcement 22.02.64.6-2.11.91.1-1.2-1.6-1.61.71.4-2.0-1.61.5-0.9-1.91.90.9
Bone: marrow area4.18.811.3-3.43.12.9-2.9-3.3-3.23.23.3-3.1-3.02.9-2.7-3.02.80.8
Bone: maximum diameter3.56.59.5-2.42.73.1-3.1-2.8-2.82.72.7-2.5-2.52.4-2.9-2.11.61.1
Bone: maximum force3.25.67.2-2.62.52.4-2.4-2.7-2.62.62.5-2.3-2.42.3-2.3-2.42.10.6
Bone: maximum moment3.76.38.1-2.72.62.7-2.7-2.8-2.82.82.7-2.4-2.52.3-2.6-2.42.10.6
Mean time between licks in bursts0.30.50.8-0.80.80.8-0.8-0.6-0.70.60.9-0.7-0.50.4-0.5-0.70.70.5
Mean num. licks in bursts0.20.20.7-0.30.30.8-0.8-0.4-0.40.40.5-0.3-0.30.4-0.5-0.30.2-0.3
Cd content in liver0.50.61.0-1.00.80.6-0.6-0.9-0.90.80.5-0.8-0.70.3-0.5-1.00.90.4
Co content in liver0.50.61.3-0.70.81.2-1.2-0.8-0.80.80.7-0.6-0.60.5-1.0-0.50.30.3
Cu content in liver0.40.51.20.9-0.7-0.00.00.60.6-0.7-0.60.80.6-0.8-0.11.0-1.1-0.3
Fe content in liver0.70.83.70.10.41.9-1.9-0.4-0.60.50.4-0.1-0.40.4-1.50.4-0.80.7
K content in liver1.91.92.41.5-1.6-1.21.21.31.4-1.5-1.51.61.3-1.61.21.3-1.2-1.0
Mg content in liver0.20.20.30.4-0.5-0.50.50.20.3-0.3-0.40.40.2-0.60.30.3-0.2-0.4
Mn content in liver0.00.10.20.10.10.4-0.4-0.2-0.20.20.2-0.1-0.10.4-0.40.0-0.10.1
Na content in liver2.02.13.31.8-1.6-0.90.91.51.5-1.6-1.71.71.5-1.51.11.6-1.6-0.2
Rb content in liver0.30.30.70.7-0.6-0.50.40.50.5-0.5-0.80.50.4-0.40.10.8-0.9-0.6
Se content in liver2.53.14.62.1-2.1-1.21.21.71.8-1.9-1.92.11.7-2.11.21.9-1.9-0.5
Sr content in liver4.74.35.82.2-2.3-1.81.82.32.3-2.3-2.22.22.3-2.41.92.1-1.9-0.1
Zn content in liver0.40.50.9-0.90.80.6-0.6-0.7-0.70.70.7-0.7-0.70.3-0.4-0.91.00.2
Bone: minimum diameter1.62.93.8-1.91.82.0-1.9-1.8-1.81.81.7-1.7-1.71.4-1.4-1.81.60.7
Time in familiar zone, hab. session 11.31.21.6-1.21.11.0-1.0-1.2-1.21.21.0-1.2-1.21.3-1.1-1.00.90.4
Time in novel zone, hab. session 14.14.07.61.6-2.1-2.72.72.02.0-2.0-2.12.01.8-2.12.41.2-0.8-1.2
Total zone transitions, hab. session 18.211.517.34.2-3.6-2.12.13.73.6-3.7-4.03.73.5-3.52.34.0-4.0-0.4
Total locomotion distance, hab. session 15.78.115.23.5-3.0-1.11.13.12.9-3.1-3.23.23.1-3.01.33.8-3.90.3
Locomotion velocity, hab. session 14.25.913.43.2-2.4-0.30.32.62.5-2.6-2.62.62.7-2.50.83.4-3.70.6
Time in familiar zone, hab. session 20.10.10.5-0.00.20.4-0.40.20.1-0.00.1-0.30.00.10.5-0.20.40.7
Time in novel zone, hab. session 20.20.21.2-0.2-0.2-1.01.0-0.3-0.10.10.10.3-0.2-0.0-0.1-0.10.1-1.1
Total zone transitions, hab. session 23.95.06.72.5-2.5-2.12.12.52.5-2.5-2.62.22.3-2.32.22.2-1.9-0.6
Total locomotion distance, hab. session 21.41.83.71.7-1.4-0.10.21.41.4-1.5-1.31.51.5-1.40.51.8-1.90.5
Locomotion velocity, hab. session 21.11.53.61.6-1.30.2-0.21.31.2-1.3-1.21.31.4-1.20.31.8-1.90.6
Novel to familiar place preference ratio0.30.31.50.30.10.7-0.7-0.2-0.20.1-0.20.4-0.10.1-1.20.7-1.10.4
Novelty place preference0.40.42.10.7-0.30.4-0.40.10.1-0.2-0.50.80.2-0.3-1.01.1-1.50.2
Time in novel zone, NPP test0.50.52.30.8-0.50.2-0.20.20.2-0.4-0.61.00.3-0.4-0.81.2-1.5-0.0
Total zone transitions, NPP test2.94.15.82.1-2.3-2.42.42.12.1-2.2-2.42.01.8-1.92.21.6-1.3-0.8
Total locomotion distance, NPP test0.70.91.41.1-1.2-1.01.01.01.0-1.1-0.91.11.1-0.90.81.0-0.90.1
Locomotion velocity, NPP test0.40.50.80.9-0.9-0.60.60.80.8-0.8-0.70.80.9-0.60.60.8-0.70.3
Intraocular pressure1.41.93.7-1.31.21.1-1.1-1.7-1.61.51.9-1.1-1.71.4-1.9-1.00.7-0.2
Delta distance traveled before/after self-admin0.30.30.70.5-0.30.6-0.60.80.6-0.7-0.80.30.3-0.80.40.6-0.70.1
Delta ambulatory time before/after self-admin0.70.71.50.8-0.60.0-0.11.21.0-1.0-1.10.71.0-1.00.81.0-1.00.1
Parametrial fat weight0.81.52.61.2-1.2-1.21.21.51.4-1.4-1.31.20.8-1.51.60.9-0.7-0.2
Pavlov. Cond. lever latency0.20.30.70.2-0.6-0.80.80.40.5-0.5-0.30.60.4-0.50.70.2-0.1-0.8
Pavlov. Cond. magazine entry latency0.20.31.10.5-0.10.7-0.7-0.1-0.1-0.0-0.00.40.1-0.1-1.00.8-1.10.6
Pavlov. Cond. change in total contacts0.30.30.50.7-0.5-0.40.40.40.5-0.5-0.50.50.6-0.50.10.7-0.70.6
Pavlov. Cond. index score0.10.20.70.20.20.7-0.7-0.3-0.30.20.1-0.1-0.10.2-0.90.3-0.50.7
Pavlov. Cond. latency score0.20.31.2-0.00.40.8-0.8-0.5-0.50.40.3-0.3-0.40.5-1.10.1-0.40.7
Pavlov. Cond. lever contacts0.30.40.9-0.30.80.8-0.8-0.6-0.70.60.5-0.7-0.50.7-0.9-0.30.10.7
Pavlov. Cond. magazine entry number0.20.21.3-0.0-0.3-0.60.60.50.4-0.4-0.30.10.2-0.31.1-0.30.5-0.7
Pavlov. Cond. intertrial magazine entries1.62.03.81.3-1.5-1.31.31.71.6-1.5-1.51.31.6-1.71.90.9-0.6-0.7
Pavlov. Cond. lever-magazine prob. diff.0.10.20.60.20.20.6-0.6-0.2-0.20.20.0-0.1-0.10.2-0.80.3-0.50.8
Pavlov. Cond. response bias0.20.21.0-0.00.40.6-0.6-0.4-0.40.40.2-0.2-0.30.4-1.00.1-0.40.7
Pavlov. Cond. lever latency0.50.61.30.9-0.8-1.21.20.70.8-0.7-0.80.90.6-0.40.40.9-0.9-0.2
Pavlov. Cond. magazine entry latency0.70.91.91.1-0.9-0.20.21.11.0-1.1-0.80.91.1-1.40.81.0-1.0-0.0
Pavlov. Cond. change in total contacts0.30.40.7-0.70.60.7-0.7-0.5-0.60.60.7-0.8-0.50.3-0.2-0.70.80.2
Pavlov. Cond. index score0.10.10.6-0.10.10.7-0.70.1-0.0-0.00.1-0.30.1-0.40.1-0.10.10.3
Pavlov. Cond. latency score0.30.41.5-0.40.61.2-1.2-0.4-0.50.40.6-0.7-0.30.1-0.4-0.40.40.4
Pavlov. Cond. lever contacts0.40.51.4-0.70.71.2-1.2-0.5-0.60.60.6-0.8-0.50.3-0.4-0.70.70.3
Pavlov. Cond. magazine entry number0.30.30.9-0.60.50.2-0.2-0.8-0.70.70.5-0.3-0.70.9-0.8-0.50.4-0.0
Pavlov. Cond. intertrial magazine entries0.10.10.20.30.00.5-0.5-0.1-0.10.1-0.00.30.10.1-0.50.2-0.40.1
Pavlov. Cond. lever-magazine prob. diff.0.10.10.50.00.10.7-0.70.20.1-0.10.0-0.30.1-0.40.2-0.10.10.4
Pavlov. Cond. response bias0.00.10.2-0.00.00.5-0.50.20.1-0.1-0.0-0.20.1-0.40.4-0.20.30.1
Time in closed arm before self-admin3.84.46.4-2.42.20.9-0.9-2.5-2.32.32.3-2.2-2.42.4-1.7-2.42.30.1
Time in closed arm after self-admin0.80.91.6-1.01.00.00.0-1.3-1.11.11.2-0.9-1.11.1-1.0-0.90.80.1
Time in open arm before self-admin0.40.41.30.5-0.20.6-0.50.50.4-0.4-0.50.40.6-0.4-0.31.0-1.11.1
Time in open arm after self-admin0.30.40.80.6-0.6-0.10.10.90.7-0.7-0.70.50.8-0.70.70.6-0.50.2
Bone: periosteal estimation5.010.312.4-3.43.53.5-3.5-3.4-3.53.43.4-3.3-3.22.9-3.1-3.12.71.4
Bone: periosteal perimeter5.89.612.5-3.13.33.5-3.5-3.4-3.43.33.3-3.0-3.22.9-3.3-2.72.31.4
Bone: post-yield work1.01.31.7-1.11.31.3-1.3-1.3-1.31.31.1-1.2-1.21.1-1.3-1.00.80.5
Progressive ratio test 1 active lever presses0.70.84.4-0.40.52.1-2.1-0.2-0.40.50.3-0.6-0.20.4-0.5-0.30.20.7
Progressive ratio test 1 breakpoint0.60.64.0-0.30.42.0-2.0-0.0-0.30.30.1-0.4-0.10.3-0.4-0.10.00.7
Progressive ratio test 1 inactive lever presses0.91.01.81.1-0.80.6-0.61.31.0-1.0-1.20.90.9-1.30.81.1-1.00.6
Progressive ratio test 2 active lever presses1.01.01.3-1.11.10.8-0.8-1.1-1.11.11.0-1.1-1.11.1-0.8-1.11.00.7
Progressive ratio test 2 breakpoint1.11.21.5-1.11.20.9-0.9-1.2-1.21.21.1-1.2-1.21.2-1.0-1.11.10.8
Progressive ratio test 2 inactive lever presses0.10.10.30.4-0.50.0-0.00.40.3-0.4-0.40.50.3-0.30.40.3-0.3-0.5
Incentive Sensitization - Responses0.60.61.3-0.80.8-0.30.3-0.9-0.80.80.9-0.7-1.10.6-0.5-0.80.80.7
Incentive Sensitization - Breakpoint1.01.02.0-1.11.0-0.10.1-1.2-1.11.11.2-1.0-1.40.9-0.7-1.11.10.7
Sum of active levers in priming session hrs 5-60.20.20.3-0.60.30.2-0.2-0.3-0.30.40.6-0.6-0.20.4-0.1-0.50.6-0.1
Progressive ratio0.40.51.2-0.60.70.1-0.1-1.0-0.80.90.6-0.6-0.71.0-1.1-0.40.20.2
Food seeking constrained by brief footshock10.212.516.7-4.03.74.1-4.1-3.3-3.53.63.6-4.0-3.43.6-2.3-3.93.70.6
Seeking ratio, punishment vs. effort1.51.94.1-1.61.42.0-2.0-0.8-1.11.11.2-1.6-1.21.0-0.2-1.61.70.2
Retroperitoneal fat weight0.61.82.91.5-1.4-1.21.21.51.5-1.5-1.71.40.9-1.51.31.4-1.2-0.2
Reaction time number correct0.81.11.8-1.21.20.6-0.6-1.3-1.21.21.1-1.0-1.11.1-1.1-1.00.90.4
Reaction time mean minus median1.21.62.51.5-1.6-1.01.01.41.4-1.4-1.21.21.2-1.21.31.2-1.0-0.9
Reaction time mean minus median AUC0.81.01.51.2-1.2-0.70.81.21.2-1.1-1.20.80.9-0.91.20.9-0.8-0.7
Reaction time num false alarms0.50.71.3-0.90.5-1.11.2-0.9-0.70.70.5-0.9-1.10.8-0.1-1.01.1-0.2
Reaction time num false alarms AUC0.50.71.3-1.00.7-0.90.9-1.0-0.80.80.6-0.9-1.10.9-0.3-1.01.1-0.1
Reaction time trials correct on left0.81.11.8-1.21.20.6-0.6-1.3-1.21.21.1-1.0-1.11.1-1.1-1.00.90.4
Reaction time trials on left0.91.32.0-1.31.30.7-0.7-1.4-1.31.31.2-1.1-1.21.2-1.2-1.10.90.5
Reaction time mean0.10.10.4-0.10.00.1-0.1-0.3-0.30.30.7-0.3-0.40.5-0.2-0.30.3-0.2
Reaction time mean AUC0.10.10.30.0-0.00.3-0.3-0.2-0.20.20.6-0.2-0.30.4-0.3-0.20.1-0.1
Median of all reaction times0.50.71.6-0.70.70.6-0.6-1.0-0.90.91.3-0.9-0.91.1-0.9-0.80.70.2
Reaction time omissions0.50.71.7-0.50.61.2-1.2-0.9-0.80.81.0-0.7-0.80.9-1.3-0.30.00.2
Reaction time false alarm rate0.20.31.70.2-0.4-1.31.30.10.2-0.2-0.30.1-0.1-0.10.40.00.1-0.3
Reaction time premature initiation rate0.20.20.8-0.10.3-0.90.9-0.5-0.40.40.8-0.2-0.20.5-0.5-0.20.10.4
Reaction time premature initiations0.81.12.3-1.01.2-0.40.4-1.4-1.21.21.5-1.0-1.01.3-1.2-1.00.90.6
Std. dev. reaction times0.60.81.41.0-1.1-1.21.20.90.9-0.9-0.60.80.7-0.71.00.7-0.5-0.7
Reaction time trials completed0.91.32.0-1.31.30.7-0.7-1.4-1.31.31.2-1.1-1.21.2-1.2-1.10.90.5
Reaction time trials AUC0.81.21.9-1.31.30.7-0.7-1.4-1.31.31.2-1.1-1.11.1-1.1-1.11.00.4
Run reversals in cocaine runway, females0.30.30.8-0.40.40.4-0.4-0.7-0.60.50.9-0.4-0.50.7-0.7-0.40.30.4
Run reversals in cocaine runway, males0.70.71.00.9-0.9-0.40.41.00.9-0.9-0.70.90.9-1.01.00.7-0.6-0.9
Latency to leave start box in cocaine runway0.91.02.3-0.81.11.0-1.0-1.0-1.11.01.1-0.7-0.90.9-1.5-0.40.21.1
Latency to leave start box in cocaine runway, F0.50.61.7-0.60.90.6-0.6-0.9-0.90.80.8-0.6-1.00.7-1.3-0.30.00.7
Latency to leave start box in cocaine runway, M0.50.40.9-0.60.70.9-0.9-0.6-0.70.70.5-0.5-0.70.5-0.8-0.50.30.7
Std. dev. time between licks in bursts0.50.50.8-0.90.90.9-0.9-0.7-0.70.70.9-0.8-0.60.6-0.5-0.80.70.1
Total sessions with >9 infusions0.00.00.10.1-0.10.3-0.30.10.0-0.0-0.0-0.00.10.10.1-0.10.10.2
Short access day 1 total inactive lever presses0.40.50.90.5-0.7-1.01.00.80.7-0.7-0.70.60.7-0.61.00.3-0.2-0.7
Short access day 10 total inactive lever presses0.80.81.30.8-0.8-1.21.11.01.0-1.0-1.10.80.8-1.11.10.7-0.50.3
Short access day 1 total infusions0.60.71.10.9-0.8-0.50.61.11.0-1.0-1.00.80.8-1.01.00.8-0.6-0.1
Short access day 10 total infusions0.70.82.6-0.60.91.6-1.6-0.7-0.80.80.6-0.8-0.50.9-1.0-0.50.30.9
Short access total infusions0.30.31.5-0.40.51.2-1.2-0.2-0.40.40.3-0.5-0.20.4-0.3-0.40.30.4
Short access day 1 locomotion0.50.51.91.1-0.5-0.10.10.50.5-0.6-0.60.90.6-0.7-0.41.2-1.40.5
Short access day 10 total locomotion0.30.31.50.10.30.5-0.5-0.5-0.50.40.20.1-0.30.3-1.20.4-0.70.9
Short access total locomotion0.30.30.90.5-0.10.7-0.70.10.1-0.1-0.30.50.3-0.1-0.60.7-0.90.7
One hour access (0.3 mA shock)0.50.62.2-0.90.80.1-0.1-0.5-0.60.70.7-0.9-0.60.70.3-1.31.5-0.1
Compulsive drug intake0.30.30.90.1-0.3-0.90.80.40.3-0.4-0.30.1-0.0-0.40.9-0.30.5-0.7
One hour access (shock baseline)0.81.01.4-1.01.11.2-1.2-1.0-1.01.11.1-1.0-0.61.1-0.9-0.90.80.7
Social response proportion2.32.55.41.3-1.7-1.81.81.71.8-1.6-1.61.41.7-1.92.30.9-0.4-0.6
Social responses0.30.41.3-0.4-0.0-1.11.10.10.2-0.1-0.1-0.30.2-0.21.2-0.60.90.4
Social time0.10.21.20.0-0.2-1.11.1-0.10.1-0.1-0.20.30.1-0.20.4-0.10.3-0.3
Soleus weight1.64.58.9-1.82.43.0-3.0-2.1-2.22.12.2-1.9-1.82.0-2.6-1.41.01.5
Bone: stiffness0.40.60.8-0.80.70.9-0.9-0.9-0.80.80.8-0.5-0.80.7-0.8-0.70.60.1
Tibialis anterior weight6.020.730.4-5.55.23.7-3.7-4.5-4.74.74.7-5.4-4.84.8-2.9-5.25.11.4
Time to tail flick, vehicle, before self-admin0.10.10.50.5-0.20.2-0.20.00.1-0.2-0.10.40.2-0.1-0.50.6-0.70.3
Time to tail flick, vehicle, after self-admin0.10.10.4-0.10.50.6-0.7-0.3-0.30.30.1-0.3-0.30.3-0.5-0.1-0.10.5
Time to tail flick, test, before self-admin1.51.52.7-1.51.30.4-0.4-1.4-1.31.31.6-1.3-1.31.2-0.9-1.41.4-0.2
Time to tail flick, test, after self-admin0.20.30.5-0.60.70.2-0.2-0.6-0.50.50.6-0.5-0.50.4-0.6-0.40.30.7
Delta time to tail flick, vehicle, before/after SA0.10.10.2-0.40.50.4-0.4-0.2-0.30.30.1-0.5-0.40.3-0.0-0.40.40.2
Delta time to tail flick, test, before/after SA0.90.81.61.1-0.9-0.40.40.90.9-0.9-1.11.00.9-0.90.31.2-1.30.6
Tibia length1.33.54.2-2.02.02.0-2.0-2.0-2.02.02.0-1.9-2.01.8-1.7-1.81.60.8
Ambulatory time before self-admin0.20.20.6-0.1-0.2-0.80.8-0.00.1-0.10.10.1-0.1-0.00.6-0.40.6-0.8
Ambulatory time after self-admin0.10.10.3-0.2-0.10.0-0.00.20.1-0.2-0.1-0.1-0.2-0.10.5-0.20.4-0.5
Bone: tissue strength0.90.91.30.9-1.1-1.11.10.90.9-0.9-0.81.11.0-1.10.80.8-0.7-0.8
Total heroin consumption0.10.10.90.1-0.10.3-0.2-0.5-0.40.20.40.3-0.30.2-1.00.2-0.4-0.2
Bone: trabecular number0.20.31.2-0.30.50.8-0.8-0.5-0.50.50.5-0.3-0.60.6-1.10.1-0.30.5
Bone: trabecular spacing0.71.03.5-1.21.0-0.30.3-0.8-0.70.80.9-1.2-1.10.80.5-1.61.9-0.0
Bone: trabecular thickness0.30.31.80.2-0.10.5-0.5-0.4-0.30.20.10.4-0.0-0.4-1.30.7-1.00.2
Bone: trabecular tissue density4.46.212.32.0-2.2-3.53.52.62.7-2.6-2.72.02.1-2.73.21.6-1.0-0.9
Water consumed over 24 hours2.02.33.5-1.51.81.9-1.9-1.6-1.71.71.3-1.6-1.41.6-1.7-1.20.90.6
Number of responses in last shaping day0.10.10.4-0.50.40.3-0.3-0.2-0.30.2-0.0-0.5-0.40.10.2-0.50.6-0.1