Hub : Genes

Pitpna

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver alternative polyA NM_017231.1 0.02 0.02 6.2e-03 0.01 0.01 0.01 0 3.9e-02 2.7e-02 6.0e-02 8.0e-02
2 PL alternative polyA NM_017231.1 0.07 0.05 1.1e-07 0.04 0.06 0.05 0.05 3.6e-05 7.2e-07 1.6e-06 5.9e-06
3 PL alternative polyA XM_039085772.1 0.07 0.05 1.3e-07 0.04 0.06 0.05 0.05 4.0e-05 6.2e-07 1.5e-06 4.6e-06
4 NAcc alternative polyA XM_039085772.1 0.14 0.19 3.5e-05 0.03 0.04 0.04 0.04 6.0e-04 4.3e-05 5.8e-05 1.9e-05
5 NAcc alternative polyA NM_017231.1 0.15 0.23 1.1e-04 0.02 0.03 0.03 0.03 2.3e-03 2.4e-04 5.3e-04 1.7e-04
6 PL isoform ratio XM_039085772.1 0.02 0.02 1.0e-02 0.01 0.01 0.01 0 3.6e-02 4.5e-02 5.8e-02 9.7e-02
7 Brain alternative polyA XM_039085772.1 0.09 0.07 1.6e-07 0.08 0.08 0.08 0.08 6.1e-08 3.5e-08 8.8e-08 8.0e-08
8 Liver gene expression Pitpna 0.03 0.02 1.5e-03 0.01 0.01 0.02 0.01 1.9e-02 7.5e-03 6.3e-03 9.5e-03
9 Eye intron excision ratio chr10_60434887_60440812 0.34 0.18 7.5e-04 0.3 0.24 0.21 0.3 1.5e-05 1.5e-04 3.7e-04 1.6e-05
10 Eye intron excision ratio chr10_60430987_60434857 0.3 0.17 1.5e-03 0.28 0.21 0.22 0.28 2.7e-05 3.6e-04 2.6e-04 3.3e-05
11 Brain alternative polyA NM_017231.1 0.08 0.06 8.3e-07 0.07 0.07 0.07 0.07 2.0e-07 2.3e-07 5.7e-07 5.0e-07
12 Adipose gene expression Pitpna 0.04 0.03 1.3e-04 0.02 0.03 0.03 0.03 1.0e-03 3.7e-04 7.6e-04 4.1e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density3.45.78.6-2.9-2.82.82.7-2.7-2.62.11.92.0-2.01.9-1.6
Area under the delay curve1.61.73.41.61.6-1.6-1.41.31.8-0.9-1.1-1.11.1-0.90.6
BMI with tail0.61.94.0-2.0-1.71.71.8-1.7-1.41.21.20.9-0.90.7-0.7
BMI without tail0.30.71.2-0.8-0.90.91.0-1.0-0.70.91.10.7-0.70.6-0.9
Body weight1.87.410.9-2.4-2.52.53.1-3.0-0.83.33.22.5-2.52.8-3.0
Weight adjusted by age0.50.61.3-1.0-0.90.91.0-0.9-1.20.60.50.5-0.50.3-0.4
Bone surface2.13.67.2-2.7-2.32.32.4-2.4-1.91.61.21.5-1.51.1-1.0
Bone volume2.33.97.6-2.7-2.42.42.5-2.4-2.11.71.31.6-1.61.2-1.0
Breakpoint value in progressive ratio session1.61.72.4-1.0-1.21.21.3-1.4-0.21.51.41.5-1.51.4-1.5
Number of licking bursts0.40.51.50.80.8-0.8-0.70.71.2-0.4-0.7-0.30.3-0.00.4
Context. condit. distance diff. score1.41.72.5-1.5-1.61.61.4-1.4-1.11.21.01.2-1.21.4-1.0
Locomotion velocity, session 14.24.66.1-2.1-2.22.22.3-2.3-1.62.12.52.2-2.22.0-1.9
Locomotion distance, session 10.40.51.0-1.0-0.70.70.9-0.9-0.40.60.60.6-0.60.2-0.3
Locomotion velocity, session 20.70.81.5-1.1-1.01.01.1-1.1-0.60.81.20.7-0.70.6-0.6
Locomotion distance, session 21.01.42.8-1.7-1.41.41.5-1.5-1.01.01.01.0-1.00.6-0.6
Locomotion velocity, session 33.33.88.52.62.5-2.5-2.32.22.9-1.5-1.3-0.80.8-1.61.0
Locomotion distance, session 30.20.20.90.10.3-0.3-0.20.20.2-0.5-0.5-0.20.2-1.00.5
Stereotopy head waving bouts, day 30.20.30.60.1-0.10.10.1-0.20.60.60.50.8-0.80.7-0.7
Stereotopy head waving duration, day 30.30.41.50.70.7-0.7-0.60.61.2-0.4-0.4-0.50.5-0.30.5
Locomotion velocity, session 70.50.61.8-1.2-1.01.00.9-0.9-1.30.30.50.4-0.4-0.1-0.1
Locomotion distance, session 71.01.33.7-1.6-1.51.51.3-1.3-1.90.60.70.6-0.60.4-0.4
Stereotopy head waving bouts, day 70.80.91.3-1.0-0.90.91.1-1.10.11.11.00.9-0.90.9-0.8
Stereotopy head waving duration, day 71.01.31.8-1.3-1.11.11.3-1.3-0.01.31.21.1-1.11.0-0.9
Locomotion velocity, session 80.20.20.6-0.8-0.60.60.7-0.7-0.40.30.70.1-0.10.1-0.1
Locomotion distance, session 82.33.34.5-2.0-2.02.02.1-2.1-0.81.91.91.8-1.81.6-1.5
Degree of sensitization distance1.61.62.0-1.3-1.41.41.3-1.3-1.41.21.30.9-0.91.4-1.1
Degree of sensitization stereotypy1.51.62.1-1.3-1.31.31.4-1.5-0.31.41.41.2-1.21.3-1.2
Conditioned locomotion0.50.61.30.70.6-0.6-1.01.0-0.3-1.0-1.1-0.60.6-0.60.9
Cocaine response after cond. corrected0.40.41.2-0.3-0.60.60.4-0.4-0.60.60.50.5-0.51.1-0.8
Cocaine response after cond. not corrected0.80.91.8-0.7-0.90.90.8-0.9-0.71.00.71.0-1.01.3-1.1
Cocaine response before conditioning0.80.91.8-1.2-0.90.91.3-1.3-0.41.00.90.9-0.90.4-0.7
Saline control response0.20.20.7-0.8-0.50.50.8-0.7-0.30.40.20.2-0.20.1-0.0
Bone: connectivity density4.26.611.3-3.4-3.13.13.0-3.0-2.92.11.92.0-2.01.7-1.5
Bone: cortical apparent density0.50.71.30.50.6-0.6-0.80.80.0-1.1-1.2-1.01.0-0.81.1
Bone: cortical area1.52.23.21.81.8-1.8-1.71.71.3-1.5-1.2-0.90.9-1.71.1
Bone: cortical porosity0.20.20.4-0.4-0.40.40.5-0.4-0.40.40.60.3-0.30.4-0.4
Bone: cortical porosity0.00.00.2-0.00.0-0.00.1-0.1-0.10.20.40.0-0.00.0-0.2
Bone: cortical thickness3.45.510.33.23.0-3.0-2.92.72.9-2.0-1.5-1.31.3-2.01.2
Bone: cortical thickness0.40.41.21.10.9-0.9-0.80.71.0-0.20.1-0.00.0-0.2-0.2
Bone: cortical tissue density0.40.51.00.40.4-0.5-0.60.6-0.1-0.9-1.0-0.80.8-0.60.9
Condit. Reinf. active minus inactive responses0.10.10.30.40.2-0.2-0.20.20.60.10.30.1-0.10.0-0.3
Condit. Reinf. active-inactive response ratio0.70.83.21.41.0-1.0-0.90.91.8-0.00.30.2-0.20.0-0.6
Condit. Reinf. active responses0.20.31.1-0.7-0.70.70.5-0.5-1.00.30.20.4-0.40.3-0.2
Condit. Reinf. inactive responses1.41.79.1-1.9-1.51.41.2-1.1-3.00.1-0.4-0.10.10.10.6
Incentive salience index mean0.10.20.50.1-0.10.10.1-0.20.30.40.70.5-0.50.2-0.6
Condit. Reinf. lever presses1.01.42.6-0.8-1.11.11.1-1.2-0.51.21.61.3-1.31.0-1.4
Condit. Reinf. active minus inactive responses0.30.30.5-0.7-0.60.60.7-0.7-0.40.50.40.6-0.60.3-0.3
Condit. Reinf. active-inactive response ratio0.10.10.10.1-0.00.00.0-0.10.00.20.40.4-0.40.3-0.4
Condit. Reinf. active responses0.30.31.2-1.1-0.70.70.9-0.9-0.30.40.00.2-0.2-0.20.1
Condit. Reinf. inactive responses0.50.62.0-1.4-0.70.71.0-0.9-0.5-0.0-0.6-0.40.4-0.80.8
Condit. Reinf. lever presses0.91.22.40.61.0-1.0-0.70.80.8-1.0-1.3-1.41.4-1.51.3
Condit. Reinf. lever reinforcers received0.20.30.9-1.0-0.50.50.8-0.8-0.20.2-0.20.1-0.1-0.40.3
Conditioned reinforcement - actives1.21.24.2-1.6-1.41.41.2-1.2-2.10.50.30.3-0.30.4-0.1
Conditioned reinforcement - inactives0.30.31.2-0.8-0.70.60.6-0.6-1.1-0.00.0-0.30.3-0.10.2
Conditioned locomotion0.40.51.10.40.7-0.7-0.60.60.7-0.6-0.6-0.80.8-1.10.7
Patch foraging indifference point 0 sec0.10.10.6-0.5-0.30.30.6-0.5-0.80.10.2-0.10.1-0.3-0.0
Patch foraging indifference point AUC0.70.82.00.40.6-0.6-0.70.80.4-1.0-1.4-1.01.0-0.81.1
Delay disc. indifference point, 0s delay0.00.00.2-0.10.0-0.00.2-0.20.50.30.00.3-0.30.1-0.1
Delay disc. indifference point, 16s delay0.90.91.81.11.1-1.1-1.01.01.3-0.7-0.8-1.01.0-0.50.6
Delay disc. indifference point, 2s delay1.31.52.91.41.5-1.4-1.21.21.7-0.8-1.0-1.21.2-0.80.6
Delay disc. indifference point, 24s delay0.30.30.70.60.6-0.6-0.50.50.9-0.4-0.4-0.50.5-0.50.3
Delay disc. indifference point, 4s delay0.60.72.31.11.0-1.0-0.80.81.5-0.3-0.5-0.60.6-0.30.1
Delay disc. indifference point, 8s delay0.70.71.51.11.0-1.0-0.90.81.2-0.5-0.7-0.80.8-0.50.3
Indifference point function ln k0.60.81.3-1.1-1.01.01.0-1.1-1.10.81.10.7-0.70.4-0.6
Indifference point function log k0.60.81.3-1.1-1.01.01.0-1.1-1.10.81.10.7-0.70.4-0.6
Patch foraging total patch changes 0 sec0.10.20.7-0.5-0.30.30.5-0.4-0.80.00.0-0.20.2-0.40.1
Patch foraging total patch changes 12 sec0.50.60.80.90.9-0.9-0.80.80.9-0.6-0.7-0.80.8-0.80.4
Patch foraging total patch changes 18 sec0.60.72.61.11.1-1.1-0.70.81.6-0.4-0.6-0.40.4-0.50.3
Patch foraging total patch changes 24 sec1.01.31.71.11.3-1.3-1.01.01.2-1.1-1.0-1.11.1-1.30.9
Patch foraging total patch changes 6 sec0.60.81.60.40.7-0.7-0.50.6-0.1-0.9-1.2-1.31.3-1.21.1
Patch foraging time to switch 0 sec0.40.62.41.20.9-0.9-0.80.71.50.30.4-0.20.20.5-0.7
Patch foraging water rate 0 sec0.20.30.7-0.5-0.20.20.3-0.2-0.7-0.5-0.6-0.10.1-0.80.9
Patch foraging water rate 12 sec0.00.00.1-0.1-0.10.10.3-0.30.10.10.3-0.10.1-0.1-0.1
Patch foraging water rate 18 sec1.82.44.4-2.1-1.91.82.0-1.9-1.61.31.31.1-1.11.0-0.7
Patch foraging water rate 24 sec0.10.10.2-0.4-0.20.10.3-0.2-0.4-0.1-0.3-0.40.4-0.50.4
Patch foraging water rate 6 sec0.30.51.30.50.6-0.7-0.60.70.2-0.9-0.7-0.60.6-1.10.9
Seeking ratio, delayed vs. immediate footshock2.52.93.51.51.8-1.8-1.61.61.5-1.6-1.8-1.91.9-1.91.6
Distance traveled before self-admin1.92.03.21.61.7-1.7-1.61.61.8-1.3-0.8-1.11.1-1.31.1
Distance traveled after self-admin0.00.00.20.20.1-0.1-0.10.10.30.10.40.3-0.30.0-0.2
Extensor digitorum longus weight2.911.324.4-4.9-4.34.34.1-3.9-4.52.31.92.1-2.11.8-1.1
Bone: elastic displacement0.91.02.50.70.8-0.8-0.90.90.4-1.0-0.9-1.61.6-1.01.0
Bone: elastic work3.34.36.72.62.5-2.5-2.32.32.4-1.7-1.3-1.71.7-2.11.1
Bone: endosteal estimation0.00.00.1-0.3-0.10.10.2-0.1-0.2-0.1-0.4-0.00.0-0.20.2
Bone: endosteal perimeter0.20.51.9-1.1-0.80.70.7-0.5-1.4-0.1-0.5-0.00.0-0.20.6
Epididymis fat weight3.68.511.0-3.1-3.13.13.3-3.3-1.73.12.72.9-2.92.8-2.5
Delta time in closed arm before/after self-admin0.50.40.70.50.6-0.6-0.70.70.4-0.7-0.9-0.70.7-0.60.8
Delta time in open arm before/after self-admin1.11.12.0-1.0-1.01.01.2-1.2-0.31.21.40.9-0.90.7-1.1
Diff in mean of infusions in LGA sessions1.01.11.8-0.6-0.90.90.9-1.0-0.61.11.21.2-1.21.1-1.4
Delay discount exponential model param1.41.43.2-1.5-1.51.51.3-1.2-1.80.81.00.9-0.90.8-0.5
Extinction: sum of active levers before priming1.71.72.7-1.6-1.51.51.6-1.5-1.51.11.30.8-0.80.9-0.8
Active lever presses in extinction session 61.11.01.6-1.3-1.21.21.2-1.2-0.90.91.10.8-0.80.6-0.7
Bone: final force0.30.62.20.90.8-0.8-0.50.41.50.10.20.7-0.7-0.6-0.5
Bone: final moment0.30.51.80.90.8-0.8-0.50.51.4-0.10.00.5-0.5-0.8-0.4
Food consumed during 24 hour testing period0.30.40.6-0.7-0.70.70.7-0.7-0.70.40.80.7-0.70.1-0.4
Glucose3.24.96.62.62.6-2.6-2.52.42.3-1.9-2.0-2.12.1-1.81.6
Heart weight0.30.41.2-0.3-0.20.30.5-0.50.30.70.71.1-1.10.3-0.6
Delay discount hyperbolic model param1.41.53.1-1.5-1.51.51.3-1.3-1.80.81.11.0-1.00.9-0.6
Intermittent access intake day 1-15 change1.11.02.40.10.4-0.4-0.50.6-0.8-1.3-1.3-1.31.3-1.41.5
Intermittent access intake escalation1.81.72.90.81.1-1.1-1.11.20.0-1.6-1.5-1.61.6-1.51.7
Intermittent access intake escalation 22.32.33.51.21.4-1.4-1.51.50.6-1.7-1.9-1.71.7-1.41.8
Intermitt. access day 1 inactive lever presses2.72.93.81.91.9-1.9-1.91.91.3-1.7-1.8-1.51.5-1.61.4
Intermitt. access day 15 inactive lever presses1.11.21.80.91.0-1.0-1.21.20.6-1.1-1.4-1.31.3-0.81.1
Intermitt. access escalation Index5.14.58.6-0.9-1.51.61.5-1.6-0.02.52.32.8-2.82.9-2.8
Intermittent access day 1 total infusions0.30.30.8-0.9-0.70.70.8-0.7-0.40.50.5-0.00.00.3-0.3
Intermittent access day 15 total infusions0.50.51.3-0.6-0.20.20.2-0.1-0.8-0.6-0.7-1.21.2-0.91.0
Intermittent access terminal intake (last 3 days)0.60.71.7-1.3-1.01.01.1-1.0-1.20.40.3-0.20.20.30.0
Intermittent access total infusions0.20.30.8-0.6-0.20.20.3-0.2-0.6-0.3-0.1-0.90.9-0.50.6
Intermittent access day 1 locomotion0.30.31.20.60.6-0.6-0.50.51.1-0.20.1-0.50.5-0.60.1
Intermittent access day 15 total locomotion0.80.81.50.60.8-0.8-0.80.80.7-0.9-0.8-1.21.2-1.11.0
Intermittent access total locomotion0.20.20.50.30.4-0.4-0.30.30.4-0.4-0.2-0.70.7-0.70.4
Intermittent access standard deviation3.03.26.10.51.0-1.0-1.21.3-0.9-2.2-2.3-2.32.3-2.22.5
Left kidney weight1.33.815.72.92.5-2.5-2.01.94.0-0.4-0.3-0.30.3-0.6-0.4
Right kidney weight1.02.711.92.52.2-2.1-1.61.53.5-0.0-0.10.1-0.1-0.2-0.6
Cocaine induced anxiety0.40.51.20.10.2-0.2-0.50.5-0.1-0.9-1.0-1.01.0-0.71.1
Post-drug Anxiety0.10.10.2-0.4-0.30.30.2-0.1-0.1-0.10.1-0.50.50.10.3
Baseline Anxiety0.10.10.3-0.1-0.20.20.2-0.30.10.50.60.4-0.40.5-0.5
Tail length1.95.913.4-0.5-1.21.21.8-1.91.13.23.22.8-2.83.1-3.7
Length with tail1.45.09.7-0.8-1.41.41.8-1.90.52.92.82.6-2.63.0-3.1
Length without tail1.32.94.3-1.5-1.51.51.9-1.8-0.32.11.81.7-1.71.9-1.8
Times rat made contact with spout0.50.61.91.10.9-0.9-0.70.71.4-0.10.40.6-0.6-0.4-0.3
Lifetime Intake0.30.30.9-0.5-0.20.20.1-0.1-0.8-0.4-0.3-1.01.0-0.70.7
Liver weight, left0.91.43.6-0.1-0.60.60.7-0.80.11.51.61.5-1.51.6-1.9
Liver weight, right0.91.52.8-0.5-0.90.91.0-1.0-0.31.41.61.4-1.41.6-1.7
Locomotor activity0.00.10.2-0.2-0.00.00.4-0.30.40.30.00.2-0.20.0-0.2
Locomotor testing distance0.00.00.1-0.10.0-0.00.3-0.20.20.20.20.3-0.3-0.1-0.0
Locomotor testing rearing0.10.10.3-0.5-0.30.20.3-0.3-0.20.1-0.2-0.30.30.00.3
Locomotion in novel chamber4.55.58.71.52.0-2.0-2.12.20.4-2.8-2.4-3.03.0-2.82.9
Locomotion in novel chamber post-restriction0.10.10.3-0.3-0.10.10.1-0.0-0.6-0.3-0.1-0.40.4-0.40.4
Fecal boli incidents, locomotor time 10.10.10.2-0.3-0.20.30.3-0.3-0.10.30.40.3-0.30.4-0.4
Change in fecal boli incidents, locomotor task0.10.10.40.60.4-0.4-0.50.40.5-0.1-0.1-0.00.00.1-0.2
Time >=10cm from walls, locomotor time 10.20.20.8-0.4-0.30.20.2-0.2-0.9-0.4-0.3-0.30.3-0.90.2
Bouts of movement, locomotor time 10.10.10.6-0.4-0.50.50.3-0.3-0.80.10.20.0-0.00.1-0.1
Total resting periods, locomotor time 10.20.21.2-0.4-0.50.50.2-0.2-1.1-0.1-0.1-0.10.10.10.1
Rest time, locomotor task time 10.30.30.70.00.1-0.1-0.30.4-0.7-0.7-0.8-0.80.8-0.30.7
Distance moved, locomotor task time 10.00.00.1-0.2-0.10.10.2-0.2-0.4-0.0-0.0-0.00.0-0.20.1
Vertical activity count, locomotor time 10.30.40.7-0.9-0.70.60.8-0.7-0.80.40.50.4-0.40.0-0.2
Time >=10cm from walls, locomotor time 20.80.82.11.01.0-1.0-0.90.90.7-0.9-0.9-0.50.5-1.50.5
Bouts of movement, locomotor time 20.10.10.20.40.3-0.3-0.40.30.5-0.1-0.2-0.30.30.10.0
Total resting periods, locomotor time 20.00.00.10.0-0.00.0-0.0-0.00.20.10.1-0.10.10.3-0.1
Rest time, locomotor task time 20.20.20.9-0.5-0.60.60.3-0.3-1.00.2-0.20.0-0.00.7-0.0
Distance moved, locomotor task time 20.60.71.20.50.7-0.8-0.60.60.6-0.8-0.9-1.11.1-1.01.0
Vertical activity count, locomotor time 20.40.40.80.80.8-0.8-0.70.70.9-0.5-0.3-0.50.5-0.60.4
Light reinforcement 10.00.10.3-0.00.2-0.20.2-0.20.60.20.2-0.40.4-0.10.1
Light reinforcement 21.62.16.02.01.9-1.9-1.61.52.4-0.7-0.3-1.01.0-0.80.4
Bone: marrow area0.00.00.1-0.3-0.10.10.2-0.1-0.2-0.1-0.4-0.10.1-0.20.2
Bone: maximum diameter0.30.61.70.00.3-0.3-0.40.4-0.9-1.1-0.9-0.60.6-1.31.1
Bone: maximum force0.40.72.61.21.1-1.1-0.80.71.6-0.3-0.00.4-0.4-0.7-0.2
Bone: maximum moment0.40.72.11.11.1-1.1-0.80.81.5-0.4-0.20.2-0.2-0.90.0
Mean time between licks in bursts0.50.71.5-0.1-0.30.40.5-0.51.11.10.81.0-1.01.2-1.1
Mean num. licks in bursts0.20.21.0-0.0-0.20.20.2-0.3-0.40.31.00.7-0.7-0.2-0.7
Cd content in liver0.70.81.7-1.1-1.11.11.0-0.9-0.70.80.20.6-0.61.3-0.4
Co content in liver0.20.20.60.50.6-0.6-0.40.40.8-0.3-0.6-0.20.2-0.40.2
Cu content in liver0.30.41.11.00.8-0.8-0.80.81.0-0.3-0.2-0.30.3-0.2-0.1
Fe content in liver0.70.82.0-0.1-0.40.40.5-0.50.21.00.91.4-1.41.2-1.1
K content in liver0.60.62.10.40.2-0.20.1-0.31.40.91.00.9-0.90.5-1.2
Mg content in liver0.10.10.40.20.3-0.3-0.20.20.3-0.3-0.4-0.50.5-0.70.3
Mn content in liver0.10.10.4-0.6-0.50.50.5-0.5-0.20.20.10.0-0.0-0.1-0.1
Na content in liver1.92.05.02.01.8-1.8-1.61.52.2-0.8-0.5-1.01.0-0.80.4
Rb content in liver0.50.62.3-1.2-1.00.90.9-0.9-1.50.20.20.0-0.0-0.10.2
Se content in liver0.50.71.41.21.0-1.0-1.01.01.1-0.6-0.9-0.20.2-0.30.3
Sr content in liver0.60.51.1-1.0-0.90.90.9-0.9-1.00.50.60.1-0.10.5-0.4
Zn content in liver0.20.31.2-0.7-0.60.60.4-0.3-1.1-0.1-0.3-0.20.2-0.20.3
Bone: minimum diameter0.40.72.01.31.1-1.1-1.01.01.4-0.3-0.30.0-0.0-0.10.0
Time in familiar zone, hab. session 10.50.52.5-0.9-0.60.50.4-0.3-1.6-0.5-0.5-0.50.5-0.60.8
Time in novel zone, hab. session 10.50.52.40.90.6-0.6-0.40.41.50.40.40.2-0.20.5-0.6
Total zone transitions, hab. session 10.30.52.0-1.4-0.80.81.0-1.0-0.50.30.0-0.10.1-0.20.5
Total locomotion distance, hab. session 10.20.30.8-0.9-0.60.60.8-0.70.10.60.10.4-0.40.6-0.1
Locomotion velocity, hab. session 10.20.30.9-0.9-0.60.60.7-0.7-0.10.40.00.3-0.30.30.1
Time in familiar zone, hab. session 20.80.82.1-1.4-1.21.21.1-1.0-1.20.60.30.4-0.40.6-0.1
Time in novel zone, hab. session 22.22.25.12.32.0-2.0-1.81.72.0-1.0-0.6-0.70.7-1.10.3
Total zone transitions, hab. session 20.60.81.5-1.2-0.90.91.2-1.2-0.21.00.70.9-0.90.6-0.5
Total locomotion distance, hab. session 20.20.20.5-0.4-0.30.30.5-0.50.30.60.30.7-0.70.5-0.4
Locomotion velocity, hab. session 20.10.20.4-0.3-0.20.20.4-0.40.30.50.20.7-0.70.4-0.3
Novel to familiar place preference ratio0.50.51.00.30.4-0.4-0.60.6-0.6-0.9-0.8-0.80.8-1.00.8
Novelty place preference0.10.10.40.10.2-0.2-0.30.3-0.6-0.5-0.3-0.40.4-0.60.4
Time in novel zone, NPP test0.10.10.5-0.1-0.10.1-0.00.0-0.7-0.2-0.1-0.20.2-0.30.2
Total zone transitions, NPP test0.20.31.2-1.1-0.60.60.9-0.90.30.50.20.1-0.10.10.1
Total locomotion distance, NPP test0.10.20.6-0.30.1-0.10.1-0.10.7-0.2-0.5-0.60.6-0.30.6
Locomotion velocity, NPP test0.40.61.20.10.5-0.5-0.40.40.9-0.7-0.9-1.01.0-0.81.1
Intraocular pressure0.60.82.4-0.00.3-0.4-0.50.6-0.3-1.1-1.3-1.21.2-1.01.6
Delta distance traveled before/after self-admin2.32.52.8-1.5-1.71.71.7-1.7-1.41.61.61.6-1.61.4-1.6
Delta ambulatory time before/after self-admin1.82.02.3-1.3-1.51.51.5-1.5-1.31.41.51.4-1.41.4-1.4
Parametrial fat weight9.318.222.9-4.2-4.44.44.8-4.8-2.84.74.53.9-3.94.3-4.1
Pavlov. Cond. lever latency0.10.20.6-0.3-0.10.1-0.00.1-0.5-0.3-0.8-0.60.6-0.20.7
Pavlov. Cond. magazine entry latency0.70.91.4-0.7-0.91.00.9-0.9-1.00.91.01.1-1.11.0-1.2
Pavlov. Cond. change in total contacts0.30.30.70.80.7-0.7-0.70.70.8-0.5-0.3-0.20.2-0.30.2
Pavlov. Cond. index score0.60.71.6-0.4-0.60.70.7-0.8-0.30.91.31.0-1.00.8-1.2
Pavlov. Cond. latency score0.70.92.0-0.3-0.60.60.7-0.8-0.11.11.41.2-1.20.9-1.4
Pavlov. Cond. lever contacts0.10.20.70.20.0-0.00.1-0.20.40.40.80.5-0.50.2-0.7
Pavlov. Cond. magazine entry number0.20.30.40.40.6-0.6-0.50.50.6-0.5-0.4-0.40.4-0.60.6
Pavlov. Cond. intertrial magazine entries0.20.20.8-0.30.1-0.1-0.00.10.1-0.4-0.8-0.70.7-0.50.9
Pavlov. Cond. lever-magazine prob. diff.0.50.61.2-0.5-0.70.70.7-0.8-0.40.81.10.9-0.90.7-1.0
Pavlov. Cond. response bias0.30.40.7-0.4-0.60.60.6-0.6-0.50.70.70.6-0.60.7-0.8
Pavlov. Cond. lever latency1.52.12.8-1.5-1.71.71.4-1.4-1.61.31.21.3-1.31.5-1.2
Pavlov. Cond. magazine entry latency0.80.93.91.31.3-1.3-0.90.82.0-0.2-0.2-0.20.2-0.40.0
Pavlov. Cond. change in total contacts0.81.12.61.31.4-1.4-1.11.01.6-0.8-0.7-0.40.4-1.20.6
Pavlov. Cond. index score1.92.54.41.71.9-1.9-1.61.62.1-1.2-1.3-1.21.2-1.41.2
Pavlov. Cond. latency score2.32.94.81.92.1-2.1-1.81.82.2-1.4-1.4-1.41.4-1.61.4
Pavlov. Cond. lever contacts0.91.22.71.31.4-1.4-1.11.01.6-0.7-0.7-0.90.9-0.90.7
Pavlov. Cond. magazine entry number1.01.23.3-1.5-1.51.51.2-1.1-1.80.60.60.4-0.40.8-0.4
Pavlov. Cond. intertrial magazine entries1.52.03.8-1.9-1.81.81.6-1.5-2.01.00.71.0-1.01.1-0.6
Pavlov. Cond. lever-magazine prob. diff.1.72.23.71.61.8-1.8-1.51.51.9-1.2-1.2-1.21.2-1.41.1
Pavlov. Cond. response bias1.11.53.61.51.6-1.6-1.31.21.9-0.8-0.8-0.90.9-0.90.6
Time in closed arm before self-admin2.93.34.3-1.7-1.81.81.9-1.9-1.02.02.11.9-1.91.9-1.8
Time in closed arm after self-admin0.00.00.10.30.2-0.2-0.30.30.3-0.10.20.0-0.00.30.1
Time in open arm before self-admin5.76.27.72.82.7-2.7-2.82.81.9-2.4-2.4-2.42.4-2.22.0
Time in open arm after self-admin1.21.32.21.21.2-1.2-1.21.20.8-1.2-1.0-1.11.1-1.50.9
Bone: periosteal estimation0.30.60.90.90.9-0.9-0.80.90.7-0.8-0.8-0.40.4-0.90.6
Bone: periosteal perimeter0.30.41.10.30.5-0.5-0.60.6-0.2-0.9-0.9-0.50.5-1.00.9
Bone: post-yield work0.60.82.2-0.6-0.70.70.7-0.7-0.10.90.91.5-1.50.8-0.9
Progressive ratio test 1 active lever presses0.20.20.4-0.6-0.50.50.5-0.5-0.30.30.6-0.10.10.1-0.2
Progressive ratio test 1 breakpoint0.50.51.0-1.0-0.90.90.9-0.9-0.70.60.70.2-0.20.4-0.4
Progressive ratio test 1 inactive lever presses0.91.01.60.80.9-0.9-0.90.90.3-1.1-1.1-1.21.2-1.30.9
Progressive ratio test 2 active lever presses0.20.20.4-0.5-0.30.20.2-0.2-0.7-0.3-0.2-0.60.6-0.50.5
Progressive ratio test 2 breakpoint0.20.20.5-0.4-0.20.20.1-0.1-0.7-0.4-0.4-0.70.7-0.60.6
Progressive ratio test 2 inactive lever presses0.60.71.70.10.4-0.4-0.30.4-0.3-0.9-0.5-1.31.3-1.21.1
Incentive Sensitization - Responses0.10.10.2-0.2-0.10.10.0-0.0-0.4-0.3-0.5-0.30.3-0.40.4
Incentive Sensitization - Breakpoint0.10.10.3-0.1-0.00.0-0.00.0-0.4-0.3-0.5-0.30.3-0.40.4
Sum of active levers in priming session hrs 5-62.72.63.6-1.5-1.61.61.7-1.8-1.01.61.91.6-1.61.4-1.6
Progressive ratio0.30.31.0-0.4-0.0-0.00.1-0.0-0.6-0.5-0.6-0.80.8-1.00.8
Food seeking constrained by brief footshock0.10.10.20.40.4-0.4-0.40.40.4-0.3-0.2-0.40.4-0.10.3
Seeking ratio, punishment vs. effort0.30.41.60.90.5-0.5-0.60.51.30.10.30.4-0.40.7-0.4
Retroperitoneal fat weight0.00.10.70.10.1-0.10.0-0.10.80.2-0.10.5-0.50.3-0.1
Reaction time number correct0.10.10.4-0.3-0.30.30.4-0.4-0.10.40.10.6-0.60.2-0.3
Reaction time mean minus median0.20.31.10.10.2-0.2-0.50.5-0.1-0.7-1.0-0.40.4-0.20.8
Reaction time mean minus median AUC0.30.41.1-1.0-0.80.80.5-0.5-1.0-0.1-0.50.1-0.10.20.5
Reaction time num false alarms0.50.72.0-0.10.3-0.3-0.30.4-0.4-1.0-1.2-0.90.9-1.11.4
Reaction time num false alarms AUC0.50.72.1-0.10.4-0.4-0.40.5-0.4-1.1-1.2-0.80.8-1.31.4
Reaction time trials correct on left0.10.10.4-0.3-0.30.30.4-0.4-0.10.40.10.6-0.60.2-0.3
Reaction time trials on left0.10.10.4-0.3-0.30.30.4-0.3-0.20.40.00.6-0.60.2-0.3
Reaction time mean0.10.10.40.30.2-0.2-0.60.5-0.1-0.4-0.6-0.30.30.20.3
Reaction time mean AUC0.30.51.10.60.5-0.5-1.00.8-0.1-0.8-1.0-0.70.7-0.20.7
Median of all reaction times0.10.20.60.60.4-0.4-0.80.60.2-0.4-0.5-0.30.30.20.2
Reaction time omissions0.00.00.10.10.0-0.0-0.10.1-0.3-0.2-0.30.2-0.2-0.00.0
Reaction time false alarm rate0.40.61.7-0.10.3-0.3-0.40.4-0.5-1.0-0.9-0.90.9-1.11.3
Reaction time premature initiation rate0.30.41.1-0.9-0.80.80.6-0.6-1.00.30.60.4-0.40.2-0.2
Reaction time premature initiations0.40.51.1-1.0-0.90.90.7-0.8-1.10.40.60.7-0.70.2-0.2
Std. dev. reaction times0.20.31.10.10.2-0.2-0.50.4-0.5-0.8-1.1-0.50.5-0.40.8
Reaction time trials completed0.10.10.4-0.3-0.30.30.4-0.3-0.20.40.00.6-0.60.2-0.3
Reaction time trials AUC0.10.10.3-0.3-0.30.30.4-0.3-0.20.3-0.00.6-0.60.1-0.3
Run reversals in cocaine runway, females0.90.92.20.40.7-0.7-0.60.70.5-0.9-1.5-1.21.2-0.81.2
Run reversals in cocaine runway, males0.20.10.7-0.3-0.20.2-0.10.1-0.8-0.4-0.3-0.30.3-0.10.7
Latency to leave start box in cocaine runway0.10.10.30.40.4-0.4-0.30.30.5-0.0-0.20.0-0.0-0.1-0.0
Latency to leave start box in cocaine runway, F0.10.10.40.30.3-0.3-0.10.00.70.30.20.1-0.10.2-0.4
Latency to leave start box in cocaine runway, M0.00.00.1-0.0-0.10.10.1-0.1-0.00.20.40.4-0.40.0-0.3
Std. dev. time between licks in bursts0.10.10.4-0.6-0.50.40.5-0.5-0.20.30.20.4-0.40.1-0.1
Total sessions with >9 infusions0.10.10.2-0.3-0.20.20.2-0.2-0.40.10.2-0.20.2-0.2-0.0
Short access day 1 total inactive lever presses0.20.20.4-0.6-0.60.50.6-0.6-0.60.40.30.2-0.20.2-0.4
Short access day 10 total inactive lever presses0.10.10.20.50.3-0.3-0.20.20.0-0.1-0.30.0-0.0-0.3-0.2
Short access day 1 total infusions1.11.22.20.30.6-0.6-0.70.8-0.5-1.3-1.3-1.41.4-1.51.4
Short access day 10 total infusions0.20.31.0-0.8-0.50.50.5-0.4-1.0-0.1-0.2-0.50.5-0.30.4
Short access total infusions0.50.61.3-0.30.0-0.0-0.20.3-0.8-0.8-0.9-1.21.2-0.91.0
Short access day 1 locomotion0.70.71.70.50.7-0.7-0.60.70.2-0.9-0.9-1.01.0-1.31.0
Short access day 10 total locomotion0.60.71.30.90.9-0.9-0.90.90.5-0.9-0.7-0.70.7-1.20.7
Short access total locomotion0.80.81.80.50.7-0.8-0.70.80.1-1.0-1.0-1.11.1-1.41.0
One hour access (0.3 mA shock)0.40.51.9-1.1-0.70.70.6-0.6-1.4-0.1-0.1-0.70.7-0.50.6
Compulsive drug intake0.40.41.9-0.0-0.20.20.3-0.30.10.71.40.8-0.80.6-0.9
One hour access (shock baseline)0.30.40.9-0.7-0.40.40.3-0.2-0.9-0.4-0.7-0.80.8-0.50.8
Social response proportion3.84.16.3-1.5-1.81.81.9-2.0-0.92.12.42.5-2.51.9-2.3
Social responses2.02.63.3-1.5-1.61.61.8-1.8-0.61.81.81.8-1.81.4-1.6
Social time3.24.35.1-2.2-2.22.22.2-2.2-1.52.11.92.1-2.12.1-1.8
Soleus weight4.412.815.1-3.5-3.63.63.8-3.9-1.93.93.93.6-3.63.6-3.4
Bone: stiffness1.32.14.3-1.1-1.21.21.4-1.4-0.41.51.52.1-2.11.1-1.6
Tibialis anterior weight5.518.836.3-6.0-5.35.35.5-5.3-5.13.63.12.7-2.72.5-2.3
Time to tail flick, vehicle, before self-admin5.65.78.1-2.8-2.82.82.8-2.8-2.32.31.92.0-2.02.0-1.8
Time to tail flick, vehicle, after self-admin0.20.20.8-0.9-0.60.60.6-0.5-0.80.0-0.2-0.10.1-0.10.4
Time to tail flick, test, before self-admin0.40.40.6-0.8-0.70.70.7-0.7-0.80.50.50.3-0.30.4-0.3
Time to tail flick, test, after self-admin0.40.41.1-0.4-0.60.60.5-0.5-0.50.71.00.6-0.60.8-0.7
Delta time to tail flick, vehicle, before/after SA1.71.72.51.01.2-1.2-1.31.30.6-1.5-1.3-1.41.4-1.41.6
Delta time to tail flick, test, before/after SA0.00.00.2-0.1-0.10.1-0.00.0-0.5-0.2-0.1-0.00.0-0.00.2
Tibia length0.41.02.90.60.2-0.10.1-0.21.41.10.91.3-1.31.0-1.7
Ambulatory time before self-admin1.81.94.51.81.7-1.7-1.61.52.1-1.0-0.8-0.80.8-0.90.7
Ambulatory time after self-admin0.80.92.3-0.0-0.30.40.5-0.60.51.11.51.2-1.21.1-1.4
Bone: tissue strength1.51.43.31.61.5-1.5-1.31.31.8-0.8-0.9-0.10.1-1.10.4
Total heroin consumption4.35.06.3-2.3-2.42.42.5-2.5-1.72.32.42.2-2.21.8-2.1
Bone: trabecular number3.14.98.4-2.9-2.72.72.6-2.6-2.41.91.61.5-1.51.8-1.3
Bone: trabecular spacing0.70.91.31.11.1-1.1-1.01.00.6-0.9-0.8-0.80.8-1.10.7
Bone: trabecular thickness0.30.30.4-0.7-0.60.60.6-0.6-0.50.50.40.6-0.60.4-0.3
Bone: trabecular tissue density2.02.94.12.01.9-1.9-1.91.91.7-1.6-1.6-1.61.6-1.21.2
Water consumed over 24 hours0.30.41.00.30.1-0.10.1-0.20.70.61.00.9-0.90.5-0.9
Number of responses in last shaping day1.81.82.81.11.3-1.3-1.21.30.7-1.3-1.3-1.71.7-1.71.2