Hub : Traits : Tibialis anterior weight : ← : →

chr2:90,475,129-95,173,253

Trait: Tibialis anterior weight

Best TWAS P=3.55e-12 · Best GWAS P=7.14e-12 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Snx16	alternative TSS	XM_039103035.1	0.03	1	0.01	7.5e-03	-5.53	3.15e-08	0.03	FALSE
Adipose	Fabp12	gene expression	Fabp12	0.09	1	0.06	1.2e-07	5.38	7.53e-08	0.28	FALSE
Adipose	Hey1	gene expression	Hey1	0.04	1	0	1.1e-01	6.75	1.46e-11	0.03	FALSE
Adipose	LOC102553210	gene expression	LOC102553210	0.07	2122	0.03	2.5e-04	5.64	1.67e-08	0.59	FALSE
Adipose	Snx16	isoform ratio	XM_006232135.4	0.03	2048	0.02	3.9e-03	-5.39	7.11e-08	0.28	FALSE
Adipose	Snx16	intron excision ratio	chr2_91354845_91356529	0.04	2048	0.02	2.2e-03	-5.44	5.25e-08	0.42	FALSE
Adipose	Fabp4	mRNA stability	Fabp4	0.08	1	0.05	1.9e-06	-5.5	3.88e-08	0.41	FALSE
Adipose	Tpd52	mRNA stability	Tpd52	0.04	2108	0.01	2.3e-02	-6.41	1.44e-10	0.32	FALSE
BLA	Fabp4	gene expression	Fabp4	0.43	28	0.25	1.9e-13	5.35	8.77e-08	0.45	FALSE
BLA	Fabp5	gene expression	Fabp5	0.21	1	0.12	3.9e-07	-5.49	4.06e-08	0.03	FALSE
BLA	Hey1	gene expression	Hey1	0.08	2629	0.03	1.4e-02	6.7	2.03e-11	0.38	FALSE
BLA	Pag1	gene expression	Pag1	0.12	1	0.04	2.8e-03	5.31	1.09e-07	0.04	FALSE
BLA	Pmp2	gene expression	Pmp2	0.1	1	0.04	2.6e-03	-5.73	1.01e-08	0.06	FALSE
Brain	Pkia	alternative TSS	XM_039101565.1	0.05	59	0.01	1.6e-02	-5.35	8.94e-08	0.43	FALSE
Brain	Zfp704	alternative TSS	XM_039103595.1	0.03	2	0.01	5.0e-02	5.74	9.46e-09	0.2	FALSE
Brain	Fabp4	gene expression	Fabp4	0.19	1917	0.08	1.5e-07	5.58	2.38e-08	0.56	FALSE
Brain	Fabp5	gene expression	Fabp5	0.22	2075	0.11	2.2e-10	6.17	6.62e-10	0.82	FALSE
Brain	Zbtb10	gene expression	Zbtb10	0.16	1	0.08	4.5e-08	-6.75	1.49e-11	0.7	FALSE
Brain	Snx16	isoform ratio	NM_022289.3	0.05	2050	0.02	9.2e-03	5.73	1.02e-08	0.43	FALSE
Brain	Snx16	isoform ratio	XM_006232135.4	0.09	2050	0.05	8.9e-06	-5.26	1.41e-07	0.46	FALSE
Brain	Zfp704	isoform ratio	XM_039103595.1	0.05	11	0.02	4.5e-03	6.16	7.45e-10	0.24	FALSE
Brain	Snx16	intron excision ratio	chr2_91354845_91356529	0.13	2050	0.06	1.8e-06	-5.56	2.77e-08	0.58	FALSE
Brain	Snx16	intron excision ratio	chr2_91355443_91356529	0.04	2050	0.01	4.1e-02	5.48	4.19e-08	0.25	FALSE
Brain	Tpd52	intron excision ratio	chr2_92804650_92812941	0.04	2	0.03	1.4e-03	-6.81	9.95e-12	0.24	FALSE
Brain	Tpd52	intron excision ratio	chr2_92805700_92811676	0.05	2109	0.02	4.0e-03	-6.44	1.23e-10	0.47	FALSE
Brain	Mrps28	mRNA stability	Mrps28	0.08	2056	0.02	4.8e-03	5.78	7.27e-09	0.43	FALSE
Brain	Tpd52	mRNA stability	Tpd52	0.36	2109	0.2	3.2e-18	-5.71	1.14e-08	0.37	FALSE
Eye	Tpd52	intron excision ratio	chr2_92804650_92812941	0.29	1	0.08	2.7e-02	6.75	1.46e-11	0.06	FALSE
IL	Impa1	alternative TSS	NM_032057.2	0.29	46	0.07	1.1e-02	-5.63	1.83e-08	0.35	FALSE
IL	Impa1	alternative TSS	XM_006232151.4	0.26	1	0.09	3.6e-03	5.48	4.28e-08	0.05	FALSE
IL	Fabp4	gene expression	Fabp4	0.75	4	0.12	7.0e-04	5.44	5.19e-08	0.58	FALSE
IL	Fabp5	gene expression	Fabp5	0.27	2075	0.09	4.0e-03	5.72	1.09e-08	0.14	FALSE
IL	Zfp704	gene expression	Zfp704	0.26	2018	0.07	9.3e-03	-5.97	2.44e-09	0.21	FALSE
IL	Tpd52	mRNA stability	Tpd52	0.59	1	0.27	3.5e-07	6.53	6.51e-11	0.12	FALSE
LHb	Fabp5	gene expression	Fabp5	0.4	97	0.1	2.8e-03	-5.34	9.29e-08	0.1	FALSE
LHb	Pag1	gene expression	Pag1	0.26	1	0.03	6.8e-02	5.37	7.88e-08	0.05	FALSE
LHb	Stmn2	gene expression	Stmn2	0.29	3009	0.04	5.2e-02	-5.75	9.18e-09	0.14	FALSE
LHb	Tpd52	gene expression	Tpd52	0.35	1	0.17	7.1e-05	6.67	2.58e-11	0.06	FALSE
LHb	Impa1	mRNA stability	Impa1	0.41	1	0.06	1.9e-02	-5.59	2.29e-08	0.05	FALSE
LHb	Tpd52	mRNA stability	Tpd52	0.47	5	0.2	1.6e-05	6.54	6.17e-11	0.5	FALSE
Liver	Fabp5	gene expression	Fabp5	0.05	2074	0.02	2.0e-03	5.29	1.22e-07	0.35	FALSE
Liver	Zbtb10	gene expression	Zbtb10	0.04	2325	0.02	4.1e-03	6.46	1.06e-10	0.44	FALSE
Liver	Chmp4c	mRNA stability	Chmp4c	0.03	2003	0.01	7.5e-03	-5.19	2.14e-07	0.27	FALSE
Liver	Tpd52	mRNA stability	Tpd52	0.13	1	0.07	3.9e-08	6.56	5.29e-11	0.39	FALSE
NAcc	Fabp4	gene expression	Fabp4	0.12	1	0.1	3.6e-11	-5.56	2.67e-08	0.54	FALSE
NAcc	Pag1	gene expression	Pag1	0.17	2135	0.11	9.7e-13	-5.96	2.49e-09	0.03	FALSE
NAcc	Pmp2	gene expression	Pmp2	0.09	1914	0.06	5.6e-08	5.63	1.75e-08	0.49	FALSE
NAcc	Tpd52	gene expression	Tpd52	0.09	2109	0.04	2.7e-05	5.65	1.61e-08	0.12	FALSE
NAcc	Zbtb10	gene expression	Zbtb10	0.1	1	0.07	3.4e-08	-6.65	2.88e-11	0.56	FALSE
NAcc	Snx16	isoform ratio	XM_006232135.4	0.04	2050	0.02	2.6e-03	-5.59	2.22e-08	0.44	FALSE
NAcc	Snx16	intron excision ratio	chr2_91354845_91356529	0.06	1	0.02	1.6e-03	5.27	1.36e-07	0.05	FALSE
NAcc	Tpd52	mRNA stability	Tpd52	0.25	2109	0.19	8.4e-22	-5.81	6.43e-09	0.57	FALSE
NAcc	Zc2hc1a	mRNA stability	Zc2hc1a	0.03	2443	0.01	3.2e-02	5.18	2.18e-07	0.46	FALSE
OFC	Fabp4	gene expression	Fabp4	0.36	1917	0.09	3.6e-03	5.7	1.17e-08	0.46	FALSE
OFC	Fabp5	gene expression	Fabp5	0.38	2075	0.13	5.4e-04	6.08	1.21e-09	0.61	FALSE
OFC	Mrps28	gene expression	Mrps28	0.37	53	0.17	6.5e-05	-6.95	3.55e-12	0.61	TRUE
OFC	Zbtb10	gene expression	Zbtb10	0.27	1	0.13	5.8e-04	-6.67	2.54e-11	0.06	FALSE
OFC	Tpd52	intron excision ratio	chr2_92804650_92805674	0.19	1	0.13	4.5e-04	6.73	1.74e-11	0.06	FALSE
OFC	Tpd52	mRNA stability	Tpd52	0.32	39	0.1	2.0e-03	6.28	3.49e-10	0.42	FALSE
PL	Tpd52	alternative TSS	NM_001401807.1	0.04	1	0.02	2.2e-03	6.57	5.10e-11	0.04	FALSE
PL	Fabp4	gene expression	Fabp4	0.43	1	0.33	9.4e-37	-5.59	2.27e-08	0.57	FALSE
PL	Fabp5	gene expression	Fabp5	0.35	2075	0.3	5.7e-33	5.7	1.20e-08	0.02	FALSE
PL	Hey1	gene expression	Hey1	0.22	17	0.09	2.1e-10	-6.75	1.51e-11	0.61	FALSE
PL	Mrps28	gene expression	Mrps28	0.11	1	0.05	3.3e-06	-6.55	5.86e-11	0.32	FALSE
PL	Pmp2	gene expression	Pmp2	0.1	1	0.06	2.8e-07	-5.49	4.06e-08	0.43	FALSE
PL	Zbtb10	gene expression	Zbtb10	0.09	1	0.03	1.2e-04	-6.67	2.58e-11	0.34	FALSE
PL	Snx16	isoform ratio	XM_006232135.4	0.03	3	0.01	2.8e-02	5.55	2.89e-08	0.41	FALSE
PL	Snx16	intron excision ratio	chr2_91354845_91356529	0.13	1	0.08	3.1e-09	5.56	2.67e-08	0.53	FALSE
PL	Tpd52	mRNA stability	Tpd52	0.33	10	0.23	8.8e-25	-6.1	1.07e-09	0.38	FALSE
pVTA	Fabp4	gene expression	Fabp4	0.17	23	0.18	2.2e-08	6.05	1.42e-09	0.5	FALSE
pVTA	Snx16	intron excision ratio	chr2_91354845_91356529	0.14	1	0.13	2.0e-06	5.69	1.30e-08	0.41	FALSE
RMTg	Tpd52	gene expression	Tpd52	0.24	47	0.13	2.3e-04	-5.28	1.29e-07	0.48	FALSE