Sdhaf2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain alternative polyA XM_017589442.3 0.03 0.02 4.7e-03 0.03 0.02 0.02 0.03 4.2e-04 6.3e-03 5.1e-03 1.3e-03
2 Brain alternative polyA XM_017589442.3 0.04 0.02 1.6e-03 0.04 0.03 0.02 0.03 2.3e-04 1.0e-03 1.2e-02 1.3e-03
3 Brain alternative polyA XM_063268376.1 0.04 0.03 2.5e-03 0.04 0.03 0.02 0.03 2.7e-04 1.4e-03 1.0e-02 8.8e-04
4 Liver alternative TSS XM_063268380.1 0.06 0.04 1.0e-03 0.01 0.01 0 0.01 3.8e-02 2.0e-02 1.8e-01 4.2e-02
5 Adipose alternative TSS XM_063268380.1 0.03 0.02 7.3e-03 0 0 -0 0 1.6e-01 1.1e-01 4.5e-01 2.7e-01
6 Liver intron excision ratio chr1_216569300_216586657 0.05 0.03 9.3e-05 0.03 0.03 0.02 0.02 7.0e-04 7.6e-04 8.8e-04 3.7e-03
7 NAcc alternative polyA XM_063268376.1 0.03 0.03 1.8e-03 0.01 0.01 0.01 0.01 8.3e-03 2.0e-02 4.0e-02 3.0e-02
8 Liver alternative polyA XM_063268367.1 0.05 0.03 5.6e-04 0.01 0.02 0.01 0.01 2.7e-02 4.9e-03 7.4e-03 1.1e-02
9 Liver alternative polyA XM_006231042.3 0.07 0.04 6.5e-05 0.02 0.03 0.02 0.02 8.8e-04 4.3e-04 8.8e-04 2.7e-03
10 Liver gene expression Sdhaf2 0.12 0.06 1.4e-06 0.04 0.04 0.04 0.04 1.2e-05 2.2e-05 5.3e-05 4.1e-05
11 Liver isoform ratio NM_001008371.1 0.16 0.1 5.2e-03 -0 0.02 0.02 -0 5.5e-01 6.1e-03 2.6e-03 4.4e-01
12 PL gene expression Sdhaf2 0.09 0.06 4.7e-05 0.04 0.04 0.04 0.04 9.6e-06 5.9e-05 7.3e-05 1.0e-04
13 NAcc isoform ratio NM_001008371.1 0.07 0.07 9.7e-04 0.02 0.02 0.02 0.01 1.5e-03 4.7e-04 1.0e-03 7.1e-03
14 pVTA alternative TSS XM_039084172.2 0.04 0.03 4.3e-03 0.03 0.02 0 0.01 3.5e-03 1.7e-02 1.2e-01 3.5e-02
15 NAcc isoform ratio XR_010055127.1 0.03 0.02 2.7e-04 0.03 0.02 0.02 0.03 5.3e-05 2.7e-04 1.6e-04 6.4e-05
16 Liver isoform ratio XM_063268376.1 0.03 0.02 5.2e-03 -0 0.01 0 -0 9.1e-01 3.5e-02 9.1e-02 4.8e-01
17 BLA gene expression Sdhaf2 0.11 0.06 1.3e-05 0.11 0.1 0.06 0.11 1.3e-06 3.4e-06 3.4e-04 1.6e-06
18 Liver alternative TSS XM_039084172.2 0.11 0.06 1.4e-03 0.01 0.02 0.01 0.01 7.0e-03 6.4e-03 1.2e-02 2.9e-02
19 Adipose gene expression Sdhaf2 0.33 0.1 1.7e-08 0.01 0.07 0.07 0.05 8.2e-03 2.2e-08 3.2e-08 5.2e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density0.10.30.60.60.6-0.6-0.1-0.7-0.8-0.30.5-0.60.30.60.40.2-0.10.5-0.80.10.7-0.5
Area under the delay curve0.10.21.30.30.3-0.30.1-0.9-1.10.20.0-0.0-0.3-0.2-0.10.20.2-0.5-0.5-0.40.8-0.2
BMI with tail2.89.920.22.82.8-2.8-2.4-1.7-0.8-3.34.0-4.23.43.23.52.4-3.53.0-4.52.94.1-1.9
BMI without tail0.31.75.31.11.1-1.1-1.4-0.50.3-1.31.6-1.51.30.81.51.5-1.60.8-1.81.02.3-0.8
Body weight3.113.624.63.93.9-3.9-3.5-0.8-0.1-3.74.2-4.23.52.74.13.6-3.74.2-4.63.85.0-3.2
Weight adjusted by age0.92.54.91.31.3-1.3-1.70.81.5-1.92.0-2.02.22.01.71.3-2.01.3-1.51.61.2-1.0
Bone surface0.81.63.81.91.9-1.9-0.8-0.8-0.9-1.01.3-1.31.01.31.01.2-0.80.7-1.60.71.3-1.3
Bone volume0.40.81.41.21.2-1.2-0.2-1.0-1.1-0.50.8-0.80.51.00.80.6-0.20.9-1.20.70.9-0.9
Breakpoint value in progressive ratio session1.62.84.71.91.9-1.9-2.22.01.9-1.81.5-1.31.81.41.72.0-1.91.6-0.81.41.0-1.2
Number of licking bursts0.10.21.0-0.1-0.10.1-0.4-0.3-0.5-0.20.3-0.30.0-0.20.50.5-0.10.8-0.50.61.0-0.6
Context. condit. distance diff. score0.10.10.2-0.3-0.30.3-0.1-0.30.1-0.10.2-0.20.20.30.50.1-0.20.2-0.40.20.4-0.4
Locomotion velocity, session 10.20.21.70.10.1-0.1-0.00.40.5-0.50.3-0.50.6-0.2-0.1-0.5-0.6-0.30.1-0.2-0.51.3
Locomotion distance, session 10.81.12.31.01.0-1.0-1.00.50.7-1.31.3-1.51.50.31.20.4-1.41.1-1.01.20.7-0.1
Locomotion velocity, session 22.22.63.61.91.9-1.9-1.70.40.5-1.81.9-1.91.91.71.51.6-1.81.2-1.71.21.6-1.2
Locomotion distance, session 20.81.12.40.60.6-0.6-1.20.71.0-1.31.2-1.21.40.11.30.7-1.51.6-0.81.61.1-0.2
Locomotion velocity, session 31.01.13.60.60.6-0.6-0.5-1.5-1.0-0.81.2-1.20.61.50.60.5-0.50.7-1.81.01.9-1.3
Locomotion distance, session 30.20.30.80.10.1-0.10.5-0.5-0.50.6-0.50.6-0.70.1-0.8-0.30.9-0.60.3-0.7-0.1-0.2
Stereotopy head waving bouts, day 30.30.41.7-0.2-0.20.20.1-1.3-1.1-0.20.5-0.70.30.2-0.0-0.4-0.4-0.1-1.00.31.10.3
Stereotopy head waving duration, day 30.30.42.2-0.1-0.10.1-0.4-0.9-0.4-0.40.7-0.70.50.50.30.4-0.70.3-1.10.51.5-0.3
Locomotion velocity, session 70.20.20.70.10.1-0.10.1-0.8-0.80.2-0.00.0-0.20.5-0.30.20.4-0.7-0.4-0.70.6-0.3
Locomotion distance, session 70.10.10.6-0.2-0.20.20.1-0.7-0.40.3-0.10.1-0.2-0.1-0.30.10.2-0.8-0.3-0.60.7-0.1
Stereotopy head waving bouts, day 70.20.20.50.60.6-0.6-0.2-0.1-0.3-0.50.5-0.50.50.70.40.2-0.60.0-0.40.30.1-0.0
Stereotopy head waving duration, day 70.81.02.31.51.5-1.5-1.00.30.1-1.01.0-0.91.00.90.91.1-1.10.8-0.91.00.9-0.7
Locomotion velocity, session 80.20.21.00.00.0-0.0-0.10.60.50.5-0.50.7-0.3-1.00.10.20.30.50.60.5-0.10.2
Locomotion distance, session 80.10.10.3-0.4-0.40.4-0.1-0.5-0.3-0.20.4-0.50.30.10.5-0.1-0.40.4-0.60.30.6-0.0
Degree of sensitization distance0.70.82.2-0.0-0.00.0-0.5-0.9-0.4-0.91.2-1.41.00.51.10.3-1.20.4-1.50.61.40.1
Degree of sensitization stereotypy0.80.91.71.31.3-1.3-0.80.30.1-1.11.1-1.01.11.31.10.9-1.10.8-0.90.80.5-0.6
Conditioned locomotion0.40.50.90.70.7-0.7-0.90.20.4-0.80.8-0.80.60.30.41.0-1.0-0.5-0.7-0.40.9-0.8
Cocaine response after cond. corrected0.20.21.0-0.8-0.80.80.0-0.10.1-0.50.3-0.50.4-0.40.3-0.4-0.30.2-0.20.00.11.0
Cocaine response after cond. not corrected0.20.21.0-0.6-0.60.60.3-0.1-0.1-0.50.3-0.60.40.10.1-0.8-0.1-0.2-0.1-0.3-0.61.0
Cocaine response before conditioning0.30.42.50.90.9-0.90.40.4-0.1-0.00.0-0.10.31.3-0.0-0.50.4-0.30.3-0.3-1.6-0.5
Saline control response1.62.24.32.12.1-2.1-1.71.31.1-1.51.3-1.21.50.21.71.6-1.51.5-0.81.60.9-1.0
Bone: connectivity density0.81.32.61.61.6-1.6-0.9-0.4-0.4-1.11.4-1.41.21.31.01.0-1.00.7-1.50.61.2-1.1
Bone: cortical apparent density0.20.31.00.70.7-0.7-0.71.00.9-0.40.2-0.10.50.80.30.7-0.40.00.1-0.1-0.1-0.6
Bone: cortical area0.20.31.51.21.2-1.2-0.2-0.0-0.2-0.20.4-0.40.30.50.30.3-0.20.1-0.40.10.0-0.7
Bone: cortical porosity0.30.31.70.10.1-0.1-0.71.21.3-0.2-0.10.30.1-0.90.40.7-0.10.30.50.2-0.1-0.5
Bone: cortical porosity0.30.31.60.30.3-0.3-0.81.21.3-0.40.10.10.4-0.80.40.9-0.40.20.30.20.0-0.4
Bone: cortical thickness1.52.55.92.42.4-2.4-1.92.42.2-1.41.0-0.81.40.11.41.7-1.31.0-0.11.00.1-1.2
Bone: cortical thickness0.20.31.10.60.6-0.6-0.30.91.00.0-0.10.20.10.5-0.30.40.0-0.70.4-0.7-0.5-0.8
Bone: cortical tissue density0.30.51.30.90.9-0.9-0.91.21.1-0.60.4-0.30.70.90.50.9-0.60.2-0.00.10.0-0.8
Condit. Reinf. active minus inactive responses1.21.42.91.21.2-1.2-1.10.91.0-1.61.4-1.61.71.01.30.4-1.71.0-0.81.20.30.1
Condit. Reinf. active-inactive response ratio1.01.13.20.80.8-0.8-1.01.61.8-1.51.0-1.21.50.21.10.3-1.50.8-0.20.9-0.20.6
Condit. Reinf. active responses1.21.53.51.11.1-1.1-1.00.30.4-1.71.7-1.91.71.61.40.3-1.61.1-1.31.20.6-0.3
Condit. Reinf. inactive responses0.30.41.5-0.1-0.10.10.2-1.1-0.9-0.30.6-0.70.31.20.4-0.4-0.20.5-0.90.40.5-0.5
Incentive salience index mean0.81.02.41.31.3-1.3-0.70.10.1-1.31.3-1.51.41.30.90.2-1.40.6-1.10.80.5-0.1
Condit. Reinf. lever presses0.30.51.71.01.0-1.0-0.0-0.8-1.0-0.40.7-0.80.41.30.1-0.0-0.3-0.2-0.90.00.4-0.6
Condit. Reinf. active minus inactive responses0.10.10.7-0.2-0.20.20.20.2-0.2-0.50.3-0.50.20.30.2-0.5-0.2-0.20.1-0.4-0.80.5
Condit. Reinf. active-inactive response ratio0.30.51.1-0.6-0.60.6-0.0-1.0-0.8-0.70.8-0.90.51.10.70.1-0.50.7-1.00.40.6-0.3
Condit. Reinf. active responses0.10.10.50.40.4-0.4-0.00.4-0.0-0.60.4-0.50.40.20.3-0.2-0.3-0.10.0-0.3-0.70.3
Condit. Reinf. inactive responses0.40.62.50.50.5-0.50.50.80.30.4-0.70.7-0.4-0.8-0.7-0.80.6-1.01.2-0.9-1.60.9
Condit. Reinf. lever presses0.91.22.41.11.1-1.1-0.7-0.3-0.5-1.31.4-1.41.21.51.40.8-1.01.2-1.31.10.7-0.9
Condit. Reinf. lever reinforcers received0.20.31.00.60.6-0.6-0.40.60.2-1.00.7-0.80.80.50.70.1-0.60.4-0.20.3-0.50.1
Conditioned reinforcement - actives0.10.21.5-0.2-0.20.20.40.30.3-0.1-0.20.1-0.00.8-0.1-0.60.4-0.20.5-0.5-1.20.4
Conditioned reinforcement - inactives0.10.41.60.10.1-0.10.2-1.0-0.9-0.40.6-0.70.41.30.5-0.3-0.20.8-0.90.60.2-0.5
Conditioned locomotion1.01.53.9-1.3-1.31.31.8-2.0-1.81.2-0.80.6-1.2-0.2-1.1-1.71.3-1.00.2-1.0-0.70.6
Patch foraging indifference point 0 sec0.10.40.90.90.9-0.9-0.80.30.1-0.50.6-0.50.6-0.20.80.8-0.50.6-0.50.50.7-0.7
Patch foraging indifference point AUC0.41.02.01.41.4-1.4-1.01.10.6-0.90.9-0.80.90.80.70.9-0.81.2-0.41.00.1-1.1
Delay disc. indifference point, 0s delay0.30.42.3-0.3-0.30.30.4-1.5-1.2-0.10.3-0.5-0.3-0.30.1-0.30.10.1-0.80.11.00.4
Delay disc. indifference point, 16s delay0.10.10.40.40.4-0.40.0-0.5-0.6-0.10.3-0.30.20.50.20.1-0.3-0.1-0.40.00.2-0.4
Delay disc. indifference point, 2s delay0.60.74.1-0.3-0.30.31.2-1.7-2.00.8-0.40.3-0.8-0.3-0.4-0.80.7-0.7-0.2-0.5-0.00.5
Delay disc. indifference point, 24s delay0.00.10.20.20.2-0.20.1-0.4-0.40.2-0.10.1-0.2-0.1-0.00.00.1-0.5-0.2-0.40.4-0.1
Delay disc. indifference point, 4s delay0.40.42.30.50.5-0.5-0.2-1.0-1.10.10.2-0.1-0.2-0.50.10.60.1-0.1-0.80.01.5-0.5
Delay disc. indifference point, 8s delay0.40.61.5-0.5-0.50.50.5-0.7-0.81.0-0.80.9-0.9-1.1-1.10.00.7-1.20.3-1.10.40.2
Indifference point function ln k0.82.55.7-2.4-2.42.41.9-1.9-1.41.4-1.21.0-1.4-0.9-1.1-1.91.4-1.50.5-1.4-0.41.6
Indifference point function log k0.82.55.7-2.4-2.42.41.9-1.9-1.41.4-1.21.0-1.4-0.9-1.1-1.91.4-1.50.5-1.4-0.41.6
Patch foraging total patch changes 0 sec0.10.40.80.90.9-0.9-0.80.70.4-0.50.5-0.40.6-0.30.80.7-0.40.5-0.30.40.5-0.7
Patch foraging total patch changes 12 sec4.35.79.13.03.0-3.0-3.02.22.2-2.52.3-2.02.51.42.22.9-2.32.3-1.52.21.7-2.5
Patch foraging total patch changes 18 sec0.20.61.31.01.0-1.0-0.81.10.8-0.70.6-0.60.6-0.50.80.6-0.70.9-0.10.9-0.0-0.3
Patch foraging total patch changes 24 sec1.86.18.32.92.9-2.9-2.90.80.9-2.52.7-2.52.31.32.32.8-2.62.7-2.42.52.8-2.9
Patch foraging total patch changes 6 sec0.60.92.51.31.3-1.3-1.00.20.1-0.60.8-0.70.70.40.91.1-0.61.3-0.81.20.9-1.6
Patch foraging time to switch 0 sec0.10.51.40.70.7-0.7-0.3-0.8-0.6-0.70.9-0.90.61.20.50.6-0.60.2-1.10.40.7-0.8
Patch foraging water rate 0 sec0.31.02.0-0.9-0.90.91.00.40.21.2-1.31.3-0.9-1.0-0.6-1.21.4-0.71.4-1.0-1.40.7
Patch foraging water rate 12 sec0.41.73.4-1.8-1.81.81.3-0.5-0.21.5-1.51.4-1.4-1.6-0.9-1.51.4-0.71.2-0.8-0.81.4
Patch foraging water rate 18 sec0.40.81.5-1.0-1.01.00.9-0.7-0.21.2-1.01.0-1.0-0.9-0.9-1.01.0-1.10.6-1.1-0.30.5
Patch foraging water rate 24 sec0.91.32.3-1.5-1.51.51.1-0.20.11.4-1.41.4-1.2-0.9-0.7-1.11.4-1.01.1-1.0-0.90.7
Patch foraging water rate 6 sec0.91.43.0-1.4-1.41.40.9-0.10.11.4-1.51.5-1.3-1.7-1.0-1.11.3-1.01.3-1.0-0.51.2
Seeking ratio, delayed vs. immediate footshock0.20.30.90.00.0-0.0-0.3-0.8-0.8-0.50.6-0.70.20.00.70.4-0.70.4-1.00.61.0-0.8
Distance traveled before self-admin0.92.03.11.81.8-1.8-1.10.00.0-1.41.6-1.61.41.71.71.1-1.01.5-1.51.71.0-1.2
Distance traveled after self-admin0.30.61.60.70.7-0.7-0.90.70.7-0.80.7-0.70.70.61.30.7-0.60.7-0.40.80.4-0.7
Extensor digitorum longus weight5.019.825.25.05.0-5.0-4.91.21.8-4.85.0-4.84.93.64.84.8-4.94.2-4.64.14.8-4.1
Bone: elastic displacement0.50.71.6-0.7-0.70.70.21.11.20.5-0.80.8-0.4-1.2-0.6-0.50.4-0.81.3-0.9-1.11.0
Bone: elastic work0.60.82.31.01.0-1.0-1.21.51.5-0.80.5-0.40.7-0.40.90.9-0.81.00.00.70.4-0.2
Bone: endosteal estimation0.92.210.6-1.5-1.51.51.9-3.3-2.81.4-0.70.5-1.40.4-1.3-1.41.3-0.9-0.6-1.10.50.3
Bone: endosteal perimeter1.33.314.2-1.9-1.91.92.4-3.8-3.31.7-1.00.8-1.80.7-1.7-1.71.7-1.3-0.5-1.40.20.7
Epididymis fat weight0.42.110.6-1.6-1.61.62.0-3.1-3.21.3-0.50.3-1.2-0.3-0.3-1.61.3-0.5-0.6-0.30.00.3
Delta time in closed arm before/after self-admin2.32.25.61.11.1-1.1-2.11.01.4-1.51.4-1.31.2-0.21.51.8-1.51.9-1.21.92.4-1.0
Delta time in open arm before/after self-admin1.51.85.81.61.6-1.6-1.30.70.7-1.51.5-1.41.62.41.31.2-1.50.6-1.10.60.4-1.5
Diff in mean of infusions in LGA sessions1.52.74.81.81.8-1.8-2.21.51.3-1.91.6-1.51.61.21.62.1-1.81.9-1.11.51.5-1.3
Delay discount exponential model param0.20.21.4-0.3-0.30.3-0.21.01.2-0.2-0.0-0.00.30.20.1-0.2-0.20.60.50.4-0.80.2
Extinction: sum of active levers before priming1.92.84.52.12.1-2.1-1.90.40.5-1.51.7-1.51.91.81.52.0-1.91.3-1.61.31.9-1.8
Active lever presses in extinction session 61.91.93.91.81.8-1.8-1.40.90.7-1.41.3-1.21.62.01.11.5-1.31.1-0.91.10.6-1.5
Bone: final force0.61.02.51.61.6-1.6-0.8-0.00.1-1.01.1-1.11.01.10.90.8-0.80.6-1.00.50.7-0.9
Bone: final moment0.61.02.51.61.6-1.6-0.80.00.1-1.01.1-1.11.01.00.90.8-0.90.6-1.00.50.7-0.9
Food consumed during 24 hour testing period0.20.41.6-0.4-0.40.40.70.20.20.7-0.70.7-0.6-0.3-0.6-0.80.9-0.50.9-0.8-1.30.5
Glucose1.92.96.5-2.2-2.22.22.1-2.3-2.11.4-1.20.9-1.6-2.0-0.7-2.31.6-0.50.4-0.9-0.22.5
Heart weight0.50.84.9-0.7-0.70.70.7-2.2-1.60.40.0-0.1-0.6-0.6-0.5-0.40.2-0.7-1.0-0.91.30.2
Delay discount hyperbolic model param0.20.31.8-0.2-0.20.2-0.31.11.3-0.40.1-0.10.40.20.2-0.0-0.30.70.40.5-0.60.1
Intermittent access intake day 1-15 change0.31.63.8-1.2-1.21.21.7-0.5-0.81.2-1.31.1-1.2-0.6-1.0-1.81.3-1.11.2-1.3-2.01.1
Intermittent access intake escalation0.31.74.3-1.3-1.31.31.7-0.5-0.81.2-1.31.1-1.2-0.4-1.0-1.91.3-1.21.3-1.2-2.11.3
Intermittent access intake escalation 20.20.41.5-0.5-0.50.50.9-0.3-0.60.6-0.50.4-0.50.2-0.3-1.00.7-0.40.5-0.5-1.20.4
Intermitt. access day 1 inactive lever presses0.00.20.7-0.8-0.80.80.6-0.3-0.00.2-0.30.1-0.20.4-0.4-0.80.3-0.00.3-0.2-0.70.4
Intermitt. access day 15 inactive lever presses0.42.14.61.21.2-1.2-0.3-1.7-1.5-1.31.7-1.91.12.01.30.2-0.91.7-2.11.81.2-1.4
Intermitt. access escalation Index0.31.12.3-1.0-1.01.01.0-0.7-1.01.1-1.01.0-1.1-1.2-1.3-0.91.1-1.50.7-1.5-0.70.2
Intermittent access day 1 total infusions0.51.510.1-0.3-0.30.30.9-3.2-2.7-0.30.9-1.20.31.10.1-0.8-0.0-0.1-1.90.21.1-0.2
Intermittent access day 15 total infusions1.22.98.2-1.7-1.71.72.6-2.8-2.91.3-1.00.6-1.3-0.1-1.3-2.61.6-1.60.1-1.3-1.31.2
Intermittent access terminal intake (last 3 days)0.71.27.2-0.7-0.70.71.5-2.7-2.60.20.2-0.5-0.20.9-0.1-1.50.6-0.4-1.0-0.1-0.20.2
Intermittent access total infusions1.11.38.5-0.7-0.70.71.6-2.9-2.80.30.2-0.5-0.30.8-0.3-1.40.7-0.8-1.1-0.40.00.1
Intermittent access day 1 locomotion0.50.94.40.10.1-0.10.3-2.1-1.6-0.51.0-1.20.61.30.3-0.3-0.40.2-1.60.51.0-0.6
Intermittent access day 15 total locomotion0.31.25.00.30.3-0.30.5-2.2-1.8-0.71.2-1.50.71.90.8-0.6-0.50.7-1.80.80.7-0.3
Intermittent access total locomotion1.72.111.90.00.0-0.01.1-3.4-3.0-0.51.2-1.60.62.30.5-1.1-0.20.2-2.20.50.7-0.5
Intermittent access standard deviation0.00.20.7-0.6-0.60.60.50.00.00.3-0.30.3-0.20.1-0.1-0.80.5-0.10.50.1-0.80.5
Left kidney weight0.21.38.1-0.6-0.60.61.4-2.8-2.70.9-0.30.2-1.0-0.3-0.7-0.80.8-0.2-0.8-0.50.7-0.2
Right kidney weight0.10.74.2-0.5-0.50.51.0-2.0-2.00.5-0.1-0.0-0.6-0.5-0.5-0.80.4-0.2-0.6-0.50.50.2
Cocaine induced anxiety0.10.10.50.30.3-0.3-0.30.70.7-0.40.2-0.20.40.6-0.00.1-0.40.40.20.1-0.50.1
Post-drug Anxiety0.30.30.70.60.6-0.6-0.40.10.2-0.60.6-0.70.60.60.50.3-0.70.9-0.50.70.2-0.0
Baseline Anxiety0.10.21.00.50.5-0.5-0.3-0.5-0.4-0.20.4-0.40.2-0.30.40.4-0.20.1-0.70.51.0-0.3
Tail length0.20.92.31.11.1-1.1-1.31.51.5-0.50.20.00.2-0.80.71.3-0.51.10.11.10.9-0.7
Length with tail1.04.58.42.52.5-2.5-2.50.91.1-1.81.9-1.61.50.72.52.6-1.82.9-1.82.62.6-2.3
Length without tail1.47.313.73.13.1-3.1-2.90.80.8-2.72.8-2.72.61.23.52.7-2.73.7-2.53.33.0-1.9
Times rat made contact with spout0.40.41.70.40.4-0.4-0.81.31.3-0.60.2-0.10.4-0.50.80.6-0.60.90.20.50.20.0
Lifetime Intake0.70.96.2-0.6-0.60.61.2-2.5-2.20.10.3-0.5-0.10.6-0.2-1.10.4-0.6-1.1-0.20.30.1
Liver weight, left0.71.22.2-1.4-1.41.41.0-0.2-0.21.0-1.11.0-1.0-1.5-0.5-1.10.7-1.51.1-1.2-0.91.5
Liver weight, right1.42.45.9-1.7-1.71.71.9-1.2-1.31.5-1.41.1-1.4-2.4-1.0-2.21.5-1.01.1-0.8-1.22.2
Locomotor activity0.91.47.6-1.0-1.01.00.70.5-0.21.2-1.41.4-1.3-2.8-0.8-1.01.2-0.31.5-0.3-0.61.5
Locomotor testing distance0.61.45.5-1.0-1.01.01.00.1-0.31.1-1.21.0-1.0-2.4-1.3-1.50.9-0.51.3-0.5-0.92.1
Locomotor testing rearing0.31.23.7-1.2-1.21.21.00.30.10.8-1.10.9-0.8-1.9-1.0-1.60.9-0.21.3-0.4-1.31.7
Locomotion in novel chamber1.31.73.4-1.3-1.31.31.8-1.5-1.81.5-1.21.1-1.3-0.6-1.0-1.61.4-1.10.7-0.8-1.11.4
Locomotion in novel chamber post-restriction0.51.42.5-1.6-1.61.61.1-0.00.01.1-1.31.2-1.2-1.0-1.2-1.20.8-1.11.3-1.0-1.31.3
Fecal boli incidents, locomotor time 10.10.31.2-0.4-0.40.40.10.2-0.0-0.80.5-0.60.20.51.0-0.40.01.1-0.11.0-0.60.2
Change in fecal boli incidents, locomotor task1.92.03.9-1.1-1.11.11.6-1.5-1.22.0-1.61.5-1.7-1.7-1.7-1.31.3-1.70.8-1.6-0.31.3
Time >=10cm from walls, locomotor time 10.60.82.2-1.1-1.11.11.3-1.5-1.30.5-0.30.2-0.61.0-0.6-1.20.8-0.7-0.1-0.6-0.80.0
Bouts of movement, locomotor time 11.92.47.50.90.9-0.9-2.02.72.4-1.91.1-1.01.10.31.91.6-1.02.40.02.30.2-0.9
Total resting periods, locomotor time 11.41.74.80.90.9-0.9-1.62.21.8-1.61.0-0.80.80.31.61.2-0.72.10.01.90.0-0.8
Rest time, locomotor task time 10.50.71.8-1.4-1.41.40.9-0.3-0.70.4-0.70.7-1.1-1.1-0.6-0.71.0-0.20.7-0.3-0.90.5
Distance moved, locomotor task time 10.10.21.40.40.4-0.40.1-0.5-0.00.30.1-0.10.51.2-0.40.0-0.3-0.7-0.3-0.70.2-0.1
Vertical activity count, locomotor time 10.21.74.9-0.9-0.90.91.3-0.6-0.41.9-1.51.5-0.9-0.1-1.8-1.11.0-2.11.1-2.2-1.10.9
Time >=10cm from walls, locomotor time 20.10.21.3-0.4-0.40.40.50.10.10.3-0.40.4-0.20.7-0.2-0.40.1-0.50.5-0.5-1.1-0.1
Bouts of movement, locomotor time 21.44.79.01.51.5-1.5-2.41.72.1-3.02.6-2.72.61.62.71.7-2.42.6-1.72.71.2-1.6
Total resting periods, locomotor time 21.04.08.61.11.1-1.1-2.21.51.8-2.92.5-2.62.41.52.61.4-2.22.4-1.72.61.1-1.4
Rest time, locomotor task time 20.50.83.0-1.7-1.71.70.7-0.5-0.50.4-0.60.4-0.7-1.2-0.4-1.00.7-0.10.50.0-0.30.9
Distance moved, locomotor task time 20.30.41.30.60.6-0.6-0.00.70.60.4-0.40.6-0.00.7-0.50.40.2-1.10.6-1.1-0.8-0.2
Vertical activity count, locomotor time 20.61.43.5-0.3-0.30.30.60.80.71.7-1.61.8-0.9-0.8-1.3-0.30.9-1.81.7-1.9-1.20.6
Light reinforcement 10.10.31.6-0.3-0.30.30.70.2-0.20.2-0.40.3-0.5-0.5-0.5-1.00.5-0.20.7-0.3-1.31.1
Light reinforcement 20.30.73.2-0.3-0.30.31.2-1.6-1.80.6-0.30.2-1.00.7-1.1-0.90.9-0.6-0.2-0.7-0.4-0.2
Bone: marrow area1.02.511.0-1.7-1.71.72.0-3.3-2.91.6-0.90.7-1.60.2-1.5-1.61.5-1.0-0.5-1.20.50.5
Bone: maximum diameter0.20.31.50.50.5-0.50.3-1.2-1.10.10.3-0.3-0.10.8-0.10.10.10.0-0.80.00.5-0.9
Bone: maximum force1.12.24.12.02.0-2.0-1.0-0.9-0.7-1.31.7-1.71.32.01.21.3-1.30.9-2.00.81.6-1.6
Bone: maximum moment1.22.24.12.02.0-2.0-1.0-0.7-0.6-1.31.7-1.71.31.91.21.3-1.31.0-1.90.81.6-1.6
Mean time between licks in bursts0.10.51.90.30.3-0.3-0.90.71.1-1.00.8-0.91.10.40.10.5-1.4-0.5-0.5-0.30.4-0.3
Mean num. licks in bursts0.10.42.0-0.0-0.00.0-0.01.31.40.0-0.40.40.1-0.4-0.2-0.3-0.2-0.41.0-0.4-1.10.8
Cd content in liver1.01.12.2-0.8-0.80.81.3-0.5-0.61.0-1.00.9-0.9-0.7-1.1-1.10.9-1.40.9-1.3-1.31.5
Co content in liver0.91.02.2-0.9-0.90.90.60.80.91.0-1.31.4-1.0-0.9-1.2-0.50.9-1.11.5-1.2-1.10.8
Cu content in liver0.10.10.6-0.1-0.10.1-0.00.30.40.5-0.50.7-0.5-0.4-0.70.20.4-0.20.4-0.20.1-0.3
Fe content in liver0.00.00.1-0.1-0.10.10.0-0.20.10.00.00.0-0.00.1-0.10.1-0.10.2-0.20.00.2-0.1
K content in liver0.20.20.70.50.5-0.5-0.1-0.6-0.8-0.20.5-0.50.30.7-0.10.3-0.10.2-0.7-0.00.4-0.6
Mg content in liver0.10.21.00.00.0-0.00.4-0.6-1.00.10.1-0.2-0.1-0.3-0.0-0.60.10.3-0.20.20.20.8
Mn content in liver2.02.33.61.91.9-1.9-1.60.30.4-1.61.7-1.61.71.81.11.8-1.50.5-1.60.51.4-1.9
Na content in liver0.20.20.50.70.7-0.70.20.2-0.1-0.40.4-0.50.40.3-0.4-0.4-0.30.2-0.10.0-0.70.4
Rb content in liver2.12.53.7-1.9-1.91.91.7-0.7-0.61.6-1.71.5-1.6-1.5-1.6-1.81.5-1.51.4-1.4-1.31.8
Se content in liver0.30.41.40.30.3-0.3-0.4-0.5-0.3-0.50.7-0.60.51.20.20.7-0.40.4-0.90.10.5-1.2
Sr content in liver4.43.85.92.22.2-2.2-2.41.41.6-2.32.1-2.02.30.92.12.2-2.41.7-1.61.71.7-1.4
Zn content in liver1.82.13.61.91.9-1.9-1.70.90.8-1.61.6-1.61.71.21.11.4-1.61.2-1.21.31.2-1.0
Bone: minimum diameter0.81.57.1-0.9-0.90.91.6-2.7-2.71.0-0.40.2-1.10.4-1.0-1.41.0-0.9-0.6-1.10.20.3
Time in familiar zone, hab. session 10.10.10.30.20.2-0.2-0.1-0.10.1-0.20.3-0.30.20.20.5-0.2-0.20.5-0.30.50.2-0.3
Time in novel zone, hab. session 11.11.22.2-1.3-1.31.31.2-0.2-0.21.0-1.21.1-1.0-1.1-1.1-1.21.1-0.91.1-0.8-1.31.5
Total zone transitions, hab. session 10.20.30.80.70.7-0.7-0.70.90.6-0.60.4-0.30.6-0.00.40.6-0.50.3-0.00.40.2-0.1
Total locomotion distance, hab. session 10.20.30.7-0.1-0.10.1-0.2-0.6-0.5-0.50.7-0.80.60.80.40.0-0.60.4-0.80.40.70.1
Locomotion velocity, hab. session 10.40.61.20.50.5-0.5-0.80.00.0-1.01.0-1.11.00.90.80.6-1.10.8-0.90.71.0-0.2
Time in familiar zone, hab. session 20.80.91.9-0.7-0.70.70.90.40.10.9-1.11.1-1.0-1.1-1.0-0.91.0-0.81.3-0.9-1.41.2
Time in novel zone, hab. session 20.60.61.20.80.8-0.8-0.7-0.20.0-0.81.0-1.10.90.80.90.5-0.90.8-1.00.80.9-0.5
Total zone transitions, hab. session 20.50.71.71.31.3-1.3-0.70.70.2-1.00.9-1.01.00.20.80.3-1.00.7-0.40.60.20.3
Total locomotion distance, hab. session 20.20.30.90.40.4-0.4-0.3-0.0-0.2-0.80.8-1.00.80.40.5-0.1-0.90.7-0.60.60.40.3
Locomotion velocity, hab. session 20.20.20.70.20.2-0.2-0.1-0.3-0.4-0.60.7-0.90.60.40.4-0.2-0.70.5-0.60.50.40.3
Novel to familiar place preference ratio1.11.53.71.51.5-1.5-1.40.00.4-1.01.1-0.90.91.01.11.7-1.00.8-1.30.91.9-1.5
Novelty place preference0.81.03.11.11.1-1.1-1.1-0.20.3-0.70.9-0.70.70.80.81.4-0.70.7-1.10.81.8-1.4
Time in novel zone, NPP test1.11.43.91.11.1-1.1-1.3-0.10.5-1.01.2-1.01.00.81.21.5-1.01.0-1.41.22.0-1.4
Total zone transitions, NPP test0.71.12.01.41.4-1.4-1.21.31.0-1.10.9-0.91.30.11.00.9-1.31.0-0.41.00.3-0.1
Total locomotion distance, NPP test0.10.10.30.40.4-0.4-0.40.40.3-0.30.3-0.30.4-0.10.20.0-0.50.3-0.10.30.30.3
Locomotion velocity, NPP test0.00.10.20.30.3-0.3-0.10.40.20.1-0.10.1-0.0-0.3-0.3-0.1-0.1-0.20.3-0.3-0.10.3
Intraocular pressure0.10.11.0-0.4-0.40.4-0.20.71.0-0.2-0.00.10.1-0.1-0.10.2-0.2-0.30.30.1-0.4-0.1
Delta distance traveled before/after self-admin0.40.41.4-0.9-0.90.90.00.70.90.3-0.70.7-0.4-1.2-0.2-0.20.1-0.80.8-0.7-0.20.5
Delta ambulatory time before/after self-admin0.40.71.4-1.1-1.11.10.20.80.90.5-0.90.9-0.6-1.2-0.4-0.40.4-0.91.1-0.9-0.70.8
Parametrial fat weight1.94.518.6-1.8-1.81.82.7-4.1-4.32.4-1.41.4-2.5-0.2-2.0-1.62.3-1.6-0.3-1.90.1-0.5
Pavlov. Cond. lever latency0.30.31.3-1.1-1.11.10.20.10.40.3-0.60.6-0.5-0.9-0.2-0.10.40.20.5-0.00.00.5
Pavlov. Cond. magazine entry latency0.70.93.41.31.3-1.3-0.4-0.3-0.5-1.01.2-1.31.01.80.80.4-1.00.4-1.10.70.3-0.4
Pavlov. Cond. change in total contacts0.30.31.20.80.8-0.8-0.1-0.0-0.3-0.60.6-0.70.61.10.2-0.1-0.4-0.4-0.4-0.1-0.4-0.4
Pavlov. Cond. index score0.30.41.21.01.0-1.0-0.30.1-0.1-0.60.6-0.70.61.10.50.2-0.60.1-0.40.4-0.2-0.4
Pavlov. Cond. latency score0.20.20.90.90.9-0.9-0.0-0.1-0.4-0.30.4-0.50.40.90.2-0.0-0.3-0.1-0.30.2-0.3-0.1
Pavlov. Cond. lever contacts0.20.20.50.70.7-0.70.2-0.4-0.6-0.00.2-0.30.10.7-0.1-0.2-0.0-0.5-0.3-0.3-0.3-0.2
Pavlov. Cond. magazine entry number0.60.72.3-1.2-1.21.20.6-0.5-0.30.9-0.90.9-0.9-1.5-0.6-0.71.0-0.30.6-0.40.10.7
Pavlov. Cond. intertrial magazine entries0.20.21.10.30.3-0.3-0.11.10.40.0-0.30.20.1-0.80.2-0.30.20.40.80.3-0.70.6
Pavlov. Cond. lever-magazine prob. diff.0.40.51.51.11.1-1.1-0.40.2-0.1-0.70.7-0.80.71.20.50.3-0.70.1-0.50.3-0.2-0.5
Pavlov. Cond. response bias0.60.72.61.21.2-1.2-0.50.20.0-0.90.9-1.00.91.60.60.5-0.90.1-0.70.3-0.1-0.7
Pavlov. Cond. lever latency1.11.53.4-0.9-0.90.90.90.20.11.6-1.71.8-1.5-1.7-1.6-0.61.4-1.31.5-1.4-0.90.9
Pavlov. Cond. magazine entry latency5.47.610.82.82.8-2.8-2.71.11.7-3.23.2-3.23.33.33.22.4-3.02.8-2.52.81.7-2.7
Pavlov. Cond. change in total contacts1.12.75.41.51.5-1.5-1.10.30.3-2.02.0-2.22.02.32.00.8-1.61.9-1.62.00.4-1.3
Pavlov. Cond. index score3.55.59.12.12.1-2.1-2.00.30.7-2.82.9-2.92.73.02.91.7-2.52.8-2.52.71.5-2.2
Pavlov. Cond. latency score3.35.38.72.02.0-2.0-1.90.20.5-2.62.8-2.92.63.02.81.7-2.42.7-2.52.71.6-2.1
Pavlov. Cond. lever contacts1.21.73.50.80.8-0.8-1.00.10.3-1.81.7-1.91.61.71.80.6-1.41.5-1.41.70.7-1.0
Pavlov. Cond. magazine entry number9.211.916.1-3.4-3.43.43.5-1.3-2.03.9-4.03.9-4.0-4.0-4.0-3.23.7-3.73.2-3.7-2.43.4
Pavlov. Cond. intertrial magazine entries1.22.65.8-1.5-1.51.51.7-0.3-0.91.8-1.91.8-1.7-2.0-1.5-1.51.7-1.21.8-1.2-1.52.4
Pavlov. Cond. lever-magazine prob. diff.3.96.09.52.32.3-2.3-2.10.50.9-2.93.0-3.02.93.13.11.8-2.62.9-2.52.91.5-2.2
Pavlov. Cond. response bias2.83.86.91.71.7-1.7-1.70.30.6-2.52.5-2.62.42.52.31.4-2.21.9-2.22.01.3-1.7
Time in closed arm before self-admin0.20.31.6-0.1-0.10.10.9-0.9-1.30.3-0.20.1-0.50.50.0-0.60.7-0.6-0.0-0.5-0.70.3
Time in closed arm after self-admin0.50.51.7-0.9-0.90.90.7-0.4-0.60.7-0.70.6-1.0-1.3-0.2-0.70.90.20.5-0.0-0.30.7
Time in open arm before self-admin1.31.66.4-1.2-1.21.20.70.20.51.6-1.71.8-1.3-2.5-1.6-0.80.9-1.01.4-1.1-0.31.1
Time in open arm after self-admin0.30.41.30.70.7-0.7-0.91.01.1-0.30.10.00.60.2-0.10.8-0.8-0.30.1-0.20.4-0.6
Bone: periosteal estimation0.30.74.6-0.1-0.10.11.0-2.2-2.00.6-0.1-0.0-0.60.8-0.6-0.60.6-0.4-0.8-0.60.5-0.5
Bone: periosteal perimeter0.20.31.90.00.0-0.00.8-1.4-1.40.3-0.0-0.1-0.40.4-0.3-0.70.4-0.1-0.4-0.1-0.10.3
Bone: post-yield work0.81.410.6-0.2-0.20.21.3-3.0-3.30.70.1-0.2-0.81.1-0.5-0.70.7-0.3-1.2-0.20.7-0.3
Progressive ratio test 1 active lever presses0.10.11.0-0.2-0.20.20.5-1.0-0.90.10.1-0.1-0.10.3-0.1-0.40.2-0.5-0.4-0.10.1-0.0
Progressive ratio test 1 breakpoint0.10.10.9-0.2-0.20.20.4-1.0-0.80.10.1-0.2-0.10.3-0.1-0.40.1-0.5-0.4-0.00.10.0
Progressive ratio test 1 inactive lever presses1.02.64.51.41.4-1.4-1.3-0.6-0.1-1.72.0-2.01.72.11.81.1-1.61.8-2.11.81.9-1.3
Progressive ratio test 2 active lever presses0.50.63.5-0.6-0.60.61.2-1.9-1.80.4-0.1-0.2-0.40.5-0.1-1.20.6-0.2-0.5-0.3-0.30.3
Progressive ratio test 2 breakpoint0.50.73.8-0.5-0.50.51.2-1.9-1.90.30.0-0.3-0.30.50.0-1.20.6-0.2-0.6-0.2-0.20.3
Progressive ratio test 2 inactive lever presses0.20.63.6-0.3-0.30.30.9-1.9-1.8-0.10.4-0.6-0.11.00.3-1.10.20.6-0.90.30.0-0.1
Incentive Sensitization - Responses0.41.12.60.80.8-0.8-0.3-1.1-1.0-1.01.3-1.41.01.61.20.2-0.91.2-1.60.81.0-0.8
Incentive Sensitization - Breakpoint0.51.02.50.70.7-0.7-0.1-1.4-1.2-0.91.2-1.40.81.61.10.1-0.71.2-1.60.70.9-0.8
Sum of active levers in priming session hrs 5-60.70.61.61.01.0-1.0-0.91.30.9-0.70.5-0.40.91.20.60.8-0.70.4-0.00.3-0.3-0.9
Progressive ratio0.10.31.8-0.0-0.00.00.3-1.4-1.1-0.30.5-0.60.01.0-0.1-0.1-0.2-0.3-0.9-0.40.4-0.3
Food seeking constrained by brief footshock0.10.20.7-0.2-0.20.20.3-0.10.3-0.1-0.10.1-0.2-0.2-0.8-0.5-0.0-0.70.2-0.8-0.40.4
Seeking ratio, punishment vs. effort0.10.21.2-0.1-0.10.1-0.30.70.9-0.0-0.20.2-0.0-1.1-0.1-0.1-0.10.20.40.20.20.3
Retroperitoneal fat weight2.310.320.8-4.0-4.04.04.0-4.4-4.63.6-2.82.5-3.6-2.6-2.5-3.33.3-2.30.9-2.6-0.91.6
Reaction time number correct0.20.72.90.70.7-0.7-0.50.91.0-0.50.2-0.10.2-0.81.50.4-0.31.70.21.60.30.6
Reaction time mean minus median0.10.72.20.90.9-0.9-0.81.21.1-0.80.7-0.61.11.50.80.9-0.80.4-0.10.5-0.4-0.2
Reaction time mean minus median AUC0.10.63.10.40.4-0.4-0.71.81.7-0.60.2-0.20.80.60.80.6-0.60.60.60.7-0.90.4
Reaction time num false alarms0.30.63.8-0.6-0.60.60.10.50.60.7-0.91.0-0.8-2.0-0.2-0.30.6-0.50.9-0.6-0.10.7
Reaction time num false alarms AUC0.20.53.6-0.1-0.10.1-0.31.01.00.4-0.70.9-0.5-1.9-0.10.30.3-0.50.9-0.60.10.5
Reaction time trials correct on left0.20.72.90.70.7-0.7-0.50.91.0-0.50.2-0.10.2-0.81.50.4-0.31.70.21.60.30.6
Reaction time trials on left0.20.73.10.70.7-0.7-0.61.01.1-0.50.2-0.10.2-0.91.60.4-0.31.70.21.60.20.6
Reaction time mean0.10.31.50.20.2-0.2-0.00.70.7-0.30.3-0.40.81.2-0.0-0.1-0.6-0.20.2-0.2-1.20.5
Reaction time mean AUC0.10.32.20.00.0-0.00.30.50.6-0.10.1-0.20.51.1-0.2-0.4-0.3-0.40.4-0.3-1.50.6
Median of all reaction times0.10.21.50.30.3-0.30.10.30.4-0.30.3-0.40.71.2-0.1-0.2-0.5-0.1-0.0-0.1-1.00.2
Reaction time omissions0.30.51.50.70.7-0.7-0.81.21.2-0.40.3-0.10.70.51.00.9-0.50.80.20.7-0.2-0.3
Reaction time false alarm rate0.40.51.8-0.5-0.50.50.20.10.10.7-0.80.8-0.7-1.2-0.9-0.20.6-1.30.6-1.30.00.1
Reaction time premature initiation rate2.23.46.52.32.3-2.3-1.6-0.7-0.3-1.41.9-1.81.62.51.22.1-1.31.1-2.31.02.4-2.4
Reaction time premature initiations1.34.07.22.72.7-2.7-2.10.40.8-1.71.9-1.71.71.82.12.3-1.52.0-1.92.02.3-2.0
Std. dev. reaction times0.10.41.80.10.1-0.1-0.21.31.2-0.0-0.20.20.40.70.00.1-0.2-0.30.8-0.2-1.30.7
Reaction time trials completed0.20.73.10.70.7-0.7-0.61.01.1-0.50.2-0.10.2-0.91.60.4-0.31.70.21.60.20.6
Reaction time trials AUC0.20.73.00.60.6-0.6-0.50.91.0-0.40.2-0.10.2-1.01.60.3-0.21.70.21.60.20.8
Run reversals in cocaine runway, females0.30.31.50.40.4-0.4-0.0-1.2-1.0-0.00.4-0.40.20.30.30.3-0.1-0.1-1.00.21.2-0.3
Run reversals in cocaine runway, males1.81.95.7-0.7-0.70.71.2-0.2-0.81.6-1.61.6-1.4-1.3-1.9-0.91.3-2.31.4-2.4-1.21.0
Latency to leave start box in cocaine runway0.71.04.7-0.6-0.60.61.3-2.1-2.21.0-0.60.5-1.1-0.1-0.7-0.91.1-0.9-0.2-1.10.20.3
Latency to leave start box in cocaine runway, F0.20.21.30.20.2-0.20.1-1.0-1.1-0.00.3-0.3-0.20.10.40.00.20.1-0.7-0.00.8-0.3
Latency to leave start box in cocaine runway, M2.32.23.3-1.6-1.61.61.8-1.6-1.61.6-1.51.4-1.8-0.4-1.7-1.41.8-1.70.8-1.7-0.81.0
Std. dev. time between licks in bursts0.20.41.8-0.6-0.60.60.5-0.3-0.10.5-0.50.5-0.5-0.5-1.1-0.60.3-1.30.4-1.2-0.40.5
Total sessions with >9 infusions0.10.20.7-0.6-0.60.60.4-0.8-0.5-0.10.1-0.20.00.4-0.2-0.40.1-0.6-0.3-0.30.00.2
Short access day 1 total inactive lever presses0.00.10.7-0.1-0.10.10.2-0.8-0.70.00.1-0.2-0.1-0.00.0-0.1-0.1-0.1-0.4-0.10.5-0.1
Short access day 10 total inactive lever presses0.00.30.8-0.8-0.80.80.20.60.90.1-0.30.3-0.1-0.2-0.4-0.60.1-0.30.6-0.7-0.70.5
Short access day 1 total infusions0.30.71.2-1.1-1.11.11.0-1.0-0.90.7-0.60.5-0.7-0.6-0.6-1.00.8-0.90.3-0.8-0.40.7
Short access day 10 total infusions0.50.85.4-0.3-0.30.30.7-2.3-1.9-0.20.7-0.90.31.0-0.2-0.7-0.1-0.2-1.40.10.6-0.2
Short access total infusions0.30.53.4-0.6-0.60.60.7-1.8-1.50.10.2-0.4-0.10.2-0.2-0.60.2-0.5-0.8-0.10.50.1
Short access day 1 locomotion0.00.10.3-0.2-0.20.20.3-0.5-0.50.1-0.10.1-0.20.3-0.2-0.20.5-0.3-0.1-0.2-0.0-0.4
Short access day 10 total locomotion0.31.24.30.10.1-0.1-0.0-1.7-1.0-1.11.4-1.71.12.10.5-0.2-0.90.8-1.90.71.1-0.7
Short access total locomotion0.40.62.40.00.0-0.00.2-1.5-1.0-0.60.9-1.10.61.40.2-0.3-0.40.3-1.40.50.7-0.5
One hour access (0.3 mA shock)0.80.94.8-1.0-1.01.01.3-2.2-2.20.4-0.1-0.1-0.60.3-0.5-1.20.8-0.3-0.6-0.30.00.0
Compulsive drug intake0.71.14.50.50.5-0.5-1.61.92.1-0.90.5-0.40.9-0.30.81.3-0.81.20.11.30.8-0.2
One hour access (shock baseline)1.23.29.8-1.6-1.61.62.6-2.8-3.11.6-1.21.0-1.7-0.2-1.7-2.41.8-1.70.3-1.7-1.40.8
Social response proportion0.30.41.10.10.1-0.10.6-0.2-0.40.9-0.91.0-0.9-0.3-0.2-0.31.0-0.70.7-0.6-0.40.2
Social responses0.40.51.50.10.1-0.10.11.00.80.6-1.01.2-0.8-0.8-0.3-0.10.8-0.71.2-0.6-0.7-0.0
Social time0.30.53.0-0.0-0.00.0-0.31.71.70.1-0.60.7-0.2-1.0-0.10.10.2-0.11.2-0.0-0.80.6
Soleus weight2.47.010.7-3.1-3.13.13.0-0.9-1.52.9-2.82.6-2.6-2.2-2.7-3.32.9-2.32.5-2.5-2.92.3
Bone: stiffness0.20.41.50.90.9-0.9-0.2-0.6-0.6-0.30.5-0.50.31.20.30.5-0.30.1-0.70.10.4-0.9
Tibialis anterior weight6.622.833.55.85.8-5.8-5.63.02.9-5.25.0-4.75.52.45.05.4-5.34.7-3.94.84.1-3.7
Time to tail flick, vehicle, before self-admin0.30.31.10.30.3-0.3-0.0-1.1-1.0-0.40.6-0.70.30.90.40.3-0.1-0.2-1.0-0.10.7-0.5
Time to tail flick, vehicle, after self-admin0.40.91.80.70.7-0.7-0.8-0.5-0.2-1.11.2-1.20.90.61.10.9-1.11.0-1.41.11.4-0.4
Time to tail flick, test, before self-admin0.30.31.70.10.1-0.1-0.0-1.2-1.1-0.10.4-0.4-0.1-0.30.30.2-0.00.2-0.90.31.3-0.1
Time to tail flick, test, after self-admin0.10.10.5-0.0-0.00.00.10.30.20.1-0.10.2-0.10.40.1-0.10.40.00.3-0.1-0.7-0.2
Delta time to tail flick, vehicle, before/after SA0.60.61.60.60.6-0.6-0.90.60.8-0.90.8-0.80.70.01.00.7-0.91.2-0.51.30.7-0.2
Delta time to tail flick, test, before/after SA0.40.53.20.30.3-0.3-0.51.81.6-0.3-0.10.10.50.8-0.00.2-0.20.00.8-0.1-1.3-0.6
Tibia length0.92.55.12.32.3-2.3-1.30.1-0.2-1.21.5-1.41.41.91.61.7-1.01.7-1.51.51.1-2.1
Ambulatory time before self-admin0.41.43.21.61.6-1.6-0.80.0-0.1-1.01.3-1.31.21.81.40.8-0.71.0-1.11.20.5-1.1
Ambulatory time after self-admin0.10.20.90.50.5-0.5-0.1-0.1-0.2-0.40.5-0.50.40.71.00.1-0.00.2-0.40.40.0-0.5
Bone: tissue strength0.80.81.4-0.9-0.90.91.0-0.2-0.50.9-0.90.9-0.9-0.8-0.9-1.01.0-1.00.9-1.2-1.10.7
Total heroin consumption4.45.29.42.82.8-2.8-3.12.72.6-2.11.9-1.52.41.72.03.0-2.32.0-1.01.91.6-2.0
Bone: trabecular number0.61.12.21.11.1-1.1-0.7-0.7-0.5-0.91.2-1.21.01.40.90.9-0.80.6-1.50.51.3-1.3
Bone: trabecular spacing0.60.92.6-0.7-0.70.70.41.31.40.3-0.80.7-0.4-1.4-0.3-1.00.4-0.31.4-0.2-1.61.4
Bone: trabecular thickness0.20.31.1-0.5-0.50.50.7-0.8-1.10.7-0.40.4-0.60.1-0.2-0.50.80.20.10.1-0.1-0.1
Bone: trabecular tissue density2.84.97.1-2.7-2.72.72.2-0.3-0.62.4-2.52.5-2.4-2.0-2.2-2.22.3-1.92.4-2.2-2.31.8
Water consumed over 24 hours0.30.51.50.80.8-0.8-0.90.60.8-0.30.3-0.10.30.50.81.0-0.20.9-0.30.60.8-1.2
Number of responses in last shaping day0.40.61.40.80.8-0.8-1.20.91.2-0.60.5-0.40.70.30.61.1-0.80.4-0.30.50.9-0.7