Hub : Genes

Rig1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver intron excision ratio chr5_60143745_60145181 0.04 0.02 2.4e-05 0.02 0.03 0.03 0.02 8.7e-04 1.4e-04 5.4e-04 1.4e-03
2 LHb gene expression Rig1 0.35 0.17 3.5e-05 0.19 0.14 0.17 0.18 2.3e-05 2.7e-04 9.4e-05 3.9e-05
3 Eye gene expression Rig1 0.43 0.19 8.6e-04 0.25 0.12 0.24 0.2 1.1e-04 6.0e-03 1.5e-04 4.6e-04
4 Adipose gene expression Rig1 0.23 0.08 0.0e+00 0.23 0.27 0.28 0.28 1.2e-25 1.8e-30 4.5e-31 9.4e-32
5 OFC gene expression Rig1 0.47 0.16 4.4e-09 0.25 0.19 0.26 0.26 1.1e-06 3.1e-05 6.0e-07 7.2e-07
6 Adipose intron excision ratio chr5_60141006_60143641 0.04 0.03 1.7e-03 0.01 0.01 0.01 0 1.3e-02 1.1e-02 2.1e-02 8.1e-02
7 NAcc mRNA stability Rig1 0.04 0.04 2.8e-04 0.03 0.03 0.03 0.01 1.3e-05 4.8e-05 7.2e-06 2.3e-03
8 Liver mRNA stability Rig1 0.05 0.03 7.6e-05 0.01 0.01 0.01 0.01 7.9e-03 1.0e-02 1.3e-02 8.2e-03
9 Adipose mRNA stability Rig1 0.06 0.04 1.1e-05 0.04 0.04 0.04 0.04 1.3e-05 2.3e-05 8.0e-05 7.0e-05
10 IL gene expression Rig1 0.31 0.15 7.5e-07 0.17 0.21 0.17 0.22 6.3e-05 9.0e-06 8.8e-05 4.3e-06
11 PL gene expression Rig1 0.54 0.13 0.0e+00 0.48 0.47 0.49 0.49 9.1e-59 9.4e-58 5.9e-61 5.5e-61
12 NAcc gene expression Rig1 0.5 0.12 0.0e+00 0.44 0.42 0.46 0.35 3.7e-73 1.4e-69 2.9e-77 1.7e-55
13 Brain gene expression Rig1 0.32 0.08 0.0e+00 0.41 0.35 0.42 0.19 1.7e-41 3.3e-34 2.8e-42 1.6e-17
14 IC gene expression Rig1 0.46 0.13 5.6e-16 0.31 0.27 0.3 0.3 2.3e-13 1.2e-11 3.7e-13 2.5e-13
15 pVTA gene expression Rig1 0.36 0.11 0.0e+00 0.34 0.29 0.32 0.33 9.0e-28 6.2e-24 5.0e-26 3.6e-27
16 BLA gene expression Rig1 0.35 0.11 0.0e+00 0.37 0.36 0.36 0.37 1.2e-20 7.8e-20 6.3e-20 1.1e-20
17 Liver intron excision ratio chr5_60141006_60143641 0.04 0.02 4.5e-03 0.01 0.01 0 0.01 1.0e-02 2.9e-02 7.6e-02 6.1e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
Bone: apparent density1.32.23.01.0-1.2-1.4-1.4-1.51.6-1.51.0-1.4-1.7-1.6-1.6-1.7-1.6-1.6-1.7-1.5
Area under the delay curve0.40.50.8-0.40.70.60.80.6-0.70.7-0.20.20.80.80.80.90.90.90.8-0.2
BMI with tail1.13.86.42.2-1.9-1.6-2.0-1.92.5-2.11.9-1.7-2.1-1.9-2.0-2.1-2.1-1.9-2.00.3
BMI without tail1.75.37.22.6-2.5-1.9-2.6-2.12.7-2.62.0-1.4-2.5-2.5-2.4-2.3-2.5-2.5-2.4-0.6
Body weight2.410.718.54.3-3.8-3.4-3.5-3.53.3-3.53.6-3.3-3.2-3.2-3.2-3.1-2.9-2.7-2.8-1.1
Weight adjusted by age0.20.30.60.7-0.6-0.8-0.5-0.5-0.3-0.60.6-0.6-0.4-0.4-0.4-0.3-0.2-0.3-0.2-0.8
Bone surface1.01.83.31.5-1.3-1.2-1.3-1.21.5-1.31.4-1.1-1.3-1.3-1.3-1.3-1.2-1.1-1.2-1.8
Bone volume0.91.63.01.2-1.2-1.1-1.2-1.21.5-1.30.8-1.0-1.3-1.3-1.2-1.3-1.3-1.2-1.3-1.7
Breakpoint value in progressive ratio session1.82.24.80.20.60.41.21.0-1.71.3-0.50.41.71.51.71.72.12.12.0-2.2
Number of licking bursts5.58.910.72.5-3.0-2.9-3.2-3.12.9-3.22.3-3.0-3.2-3.3-3.2-3.3-3.3-3.2-3.20.9
Context. condit. distance diff. score0.20.20.8-0.90.40.50.30.4-0.70.2-0.70.30.10.10.30.20.20.10.10.9
Locomotion velocity, session 10.70.75.01.3-1.0-0.8-0.6-0.5-1.4-0.30.2-0.8-0.1-0.10.20.50.40.30.6-2.2
Locomotion distance, session 10.50.67.10.8-0.8-0.7-0.5-0.5-0.8-0.4-0.1-0.5-0.4-0.4-0.10.10.1-0.00.1-2.7
Locomotion velocity, session 22.42.84.51.2-1.7-1.4-1.8-1.61.6-1.90.9-1.5-2.0-2.0-1.8-1.7-1.9-2.1-1.8-0.3
Locomotion distance, session 21.62.23.81.5-1.9-1.7-1.8-1.70.4-1.71.1-1.6-1.6-1.6-1.4-1.3-1.3-1.3-1.2-1.2
Locomotion velocity, session 30.30.42.5-0.2-0.1-0.20.1-0.0-1.50.2-0.3-0.40.10.10.30.40.60.60.5-1.6
Locomotion distance, session 30.80.81.71.0-1.1-1.1-1.0-1.00.0-0.90.8-1.3-1.1-1.1-0.9-0.8-0.5-0.6-0.7-0.7
Stereotopy head waving bouts, day 30.20.20.80.9-0.5-0.4-0.5-0.40.2-0.40.2-0.6-0.3-0.4-0.2-0.1-0.3-0.2-0.1-0.7
Stereotopy head waving duration, day 30.20.20.50.7-0.4-0.4-0.5-0.50.7-0.50.3-0.5-0.4-0.4-0.4-0.3-0.5-0.5-0.4-0.7
Locomotion velocity, session 70.20.20.6-0.50.40.50.40.5-0.50.5-0.80.20.50.50.50.40.50.20.50.1
Locomotion distance, session 70.10.10.6-0.2-0.2-0.2-0.1-0.3-0.8-0.0-0.6-0.7-0.1-0.00.1-0.00.10.20.10.5
Stereotopy head waving bouts, day 72.93.24.41.8-2.1-1.8-2.1-1.91.5-2.01.4-1.7-1.9-1.9-1.9-1.8-1.9-1.9-1.80.4
Stereotopy head waving duration, day 72.42.93.81.9-1.8-1.6-1.8-1.72.0-1.81.6-1.5-1.8-1.8-1.8-1.7-1.8-1.9-1.7-0.1
Locomotion velocity, session 80.30.30.90.5-1.0-0.7-0.7-0.6-0.8-0.7-0.1-0.6-0.5-0.5-0.3-0.1-0.3-0.3-0.1-0.4
Locomotion distance, session 80.20.21.00.1-0.8-0.6-0.6-0.5-1.0-0.5-0.1-0.7-0.5-0.5-0.3-0.2-0.1-0.2-0.1-0.5
Degree of sensitization distance0.60.72.0-1.00.80.70.70.7-0.60.7-0.90.60.90.90.80.70.60.70.71.4
Degree of sensitization stereotypy2.62.83.81.5-1.9-1.7-1.9-1.81.5-1.91.4-1.5-1.8-1.8-1.8-1.8-1.9-1.7-1.80.4
Conditioned locomotion0.50.67.40.1-0.1-0.10.20.0-1.00.3-0.4-0.30.40.40.40.60.60.50.7-2.7
Cocaine response after cond. corrected1.31.69.5-0.20.70.51.00.8-1.31.1-1.00.31.11.11.11.41.51.31.3-3.1
Cocaine response after cond. not corrected1.11.311.80.30.40.10.70.5-1.10.8-0.80.10.80.80.81.11.21.01.0-3.4
Cocaine response before conditioning1.31.62.01.3-1.2-1.2-1.3-1.21.4-1.41.2-1.0-1.3-1.4-1.4-1.3-1.3-1.4-1.40.2
Saline control response1.92.56.02.4-1.9-2.0-1.7-1.91.5-1.61.6-1.8-1.4-1.4-1.4-1.3-1.2-1.1-1.2-0.9
Bone: connectivity density0.60.92.40.6-0.6-0.8-0.7-0.81.3-0.80.7-0.6-1.0-1.0-1.0-1.0-0.9-1.0-1.1-1.5
Bone: cortical apparent density0.20.32.3-0.20.00.1-0.2-0.10.8-0.30.00.2-0.5-0.5-0.5-0.4-0.6-0.5-0.71.5
Bone: cortical area4.16.212.72.5-2.2-2.0-2.5-2.23.6-2.62.8-1.8-2.6-2.5-2.6-2.7-2.7-2.6-2.61.0
Bone: cortical porosity0.10.21.8-0.70.10.10.10.1-0.40.1-1.30.20.10.10.10.1-0.10.1-0.10.5
Bone: cortical porosity0.10.10.50.0-0.4-0.4-0.4-0.4-0.0-0.3-0.6-0.3-0.3-0.3-0.3-0.3-0.4-0.2-0.30.7
Bone: cortical thickness2.03.47.21.2-1.5-1.2-1.8-1.52.7-2.01.5-1.0-2.1-2.0-2.0-2.2-2.3-2.1-2.21.2
Bone: cortical thickness0.10.20.4-0.4-0.10.1-0.3-0.00.5-0.40.30.3-0.4-0.4-0.3-0.6-0.6-0.4-0.5-0.4
Bone: cortical tissue density0.20.22.1-0.30.10.2-0.10.00.7-0.2-0.10.3-0.4-0.4-0.3-0.3-0.4-0.3-0.51.5
Condit. Reinf. active minus inactive responses0.30.30.50.4-0.7-0.6-0.7-0.60.3-0.60.6-0.6-0.5-0.5-0.5-0.6-0.6-0.5-0.50.3
Condit. Reinf. active-inactive response ratio1.11.12.3-1.31.11.01.01.1-1.01.1-0.71.11.11.11.00.90.90.81.01.5
Condit. Reinf. active responses2.43.03.61.8-1.9-1.8-1.9-1.81.6-1.81.9-1.6-1.8-1.8-1.8-1.8-1.7-1.6-1.7-0.3
Condit. Reinf. inactive responses3.74.55.32.1-2.1-2.1-2.2-2.12.3-2.22.1-1.9-2.3-2.3-2.2-2.2-2.1-2.1-2.2-1.2
Incentive salience index mean3.23.95.22.2-2.3-2.3-2.2-2.31.6-2.12.0-2.2-1.9-1.9-2.0-2.0-1.8-1.7-1.8-0.7
Condit. Reinf. lever presses9.012.717.34.1-4.1-4.2-3.9-4.12.7-3.63.6-4.1-3.5-3.5-3.6-3.4-3.1-3.1-3.1-2.4
Condit. Reinf. active minus inactive responses0.50.72.01.0-0.7-0.7-0.7-0.81.3-0.81.4-0.7-0.6-0.6-0.7-0.8-0.7-0.5-0.70.4
Condit. Reinf. active-inactive response ratio0.00.00.2-0.0-0.00.1-0.1-0.20.4-0.20.2-0.0-0.0-0.0-0.1-0.2-0.30.1-0.20.4
Condit. Reinf. active responses1.42.04.31.8-1.2-1.4-1.3-1.42.0-1.42.1-1.3-1.2-1.2-1.3-1.4-1.3-1.1-1.20.4
Condit. Reinf. inactive responses2.43.16.62.0-1.4-1.6-1.6-1.62.6-1.72.2-1.3-1.8-1.8-1.9-1.8-1.7-1.9-1.80.1
Condit. Reinf. lever presses1.82.58.41.9-0.9-1.3-1.1-1.42.9-1.32.1-1.3-1.3-1.3-1.6-1.6-1.4-1.4-1.61.6
Condit. Reinf. lever reinforcers received1.62.35.32.0-1.3-1.5-1.3-1.52.2-1.42.3-1.5-1.3-1.3-1.4-1.5-1.3-1.2-1.30.5
Conditioned reinforcement - actives0.10.10.60.30.4-0.20.4-0.10.60.40.8-0.10.40.30.10.10.50.40.10.3
Conditioned reinforcement - inactives0.10.11.0-0.10.0-0.20.10.1-0.30.11.00.40.30.30.20.10.20.10.1-0.3
Conditioned locomotion0.10.10.5-0.50.20.00.3-0.1-0.70.40.10.00.40.40.20.30.60.50.3-0.2
Patch foraging indifference point 0 sec0.30.63.61.2-0.7-0.8-0.2-0.5-0.90.10.1-1.10.30.20.30.40.70.70.6-1.9
Patch foraging indifference point AUC4.36.210.72.9-2.6-2.5-2.6-2.42.5-2.73.3-2.2-2.5-2.6-2.5-2.5-2.3-2.5-2.3-0.3
Delay disc. indifference point, 0s delay0.70.81.9-0.60.70.30.90.5-1.11.1-0.60.31.11.00.90.91.21.40.9-0.2
Delay disc. indifference point, 16s delay1.21.42.5-0.11.11.01.31.0-1.11.20.20.41.41.21.41.51.61.51.4-1.2
Delay disc. indifference point, 2s delay0.20.21.90.2-0.0-0.3-0.1-0.40.8-0.1-0.1-0.1-0.2-0.1-0.5-0.3-0.2-0.1-0.41.4
Delay disc. indifference point, 24s delay0.20.30.4-0.30.70.50.60.5-0.30.6-0.30.00.60.60.60.60.60.60.60.1
Delay disc. indifference point, 4s delay0.10.10.2-0.50.50.40.40.4-0.50.3-0.10.30.40.30.30.30.30.40.20.3
Delay disc. indifference point, 8s delay0.00.00.30.1-0.00.1-0.1-0.10.2-0.10.3-0.5-0.1-0.1-0.1-0.0-0.1-0.1-0.10.2
Indifference point function ln k1.32.33.3-1.41.41.41.61.3-1.61.7-1.61.01.71.81.71.61.71.81.7-0.6
Indifference point function log k1.32.33.3-1.41.41.41.61.3-1.61.7-1.61.01.71.81.71.61.71.81.7-0.6
Patch foraging total patch changes 0 sec0.50.93.51.5-1.3-1.3-0.8-1.1-0.5-0.50.3-1.6-0.3-0.4-0.3-0.20.10.1-0.0-1.9
Patch foraging total patch changes 12 sec0.70.92.01.3-1.0-1.1-1.0-0.91.0-1.01.4-1.0-0.8-0.9-0.8-1.1-0.8-0.9-0.9-0.2
Patch foraging total patch changes 18 sec0.10.10.70.9-0.4-0.2-0.2-0.10.3-0.20.6-0.3-0.0-0.2-0.1-0.0-0.0-0.1-0.1-0.6
Patch foraging total patch changes 24 sec1.01.83.61.9-1.6-1.8-1.5-1.51.1-1.41.1-1.6-1.2-1.3-1.2-1.2-1.1-1.1-1.1-0.6
Patch foraging total patch changes 6 sec1.42.15.32.3-1.7-1.7-1.5-1.50.8-1.42.1-1.8-1.2-1.4-1.1-1.0-0.9-0.9-0.9-1.4
Patch foraging time to switch 0 sec1.53.15.5-2.32.12.21.92.1-1.31.8-1.42.31.61.61.61.61.41.41.30.7
Patch foraging water rate 0 sec0.71.43.21.7-1.6-1.7-1.4-1.60.4-1.21.0-1.8-1.0-1.0-1.0-1.0-0.8-0.8-0.7-0.5
Patch foraging water rate 12 sec0.10.10.30.4-0.6-0.5-0.4-0.5-0.1-0.3-0.1-0.5-0.2-0.1-0.2-0.2-0.10.00.00.5
Patch foraging water rate 18 sec0.81.22.70.5-0.7-0.9-1.0-1.01.4-1.10.3-0.7-1.1-1.1-1.2-1.3-1.3-1.3-1.31.6
Patch foraging water rate 24 sec0.30.51.1-0.3-0.6-0.4-0.8-0.60.5-0.6-0.6-0.3-0.6-0.6-0.7-0.9-1.0-0.8-0.91.1
Patch foraging water rate 6 sec1.72.54.51.3-1.9-2.1-1.8-2.01.0-1.70.8-1.8-1.6-1.5-1.7-1.6-1.6-1.5-1.5-0.2
Seeking ratio, delayed vs. immediate footshock1.01.23.11.0-0.9-1.8-0.9-1.30.7-1.01.6-1.3-0.9-0.9-1.1-1.1-0.9-0.8-1.0-0.2
Distance traveled before self-admin4.55.99.62.0-3.0-3.1-2.8-3.10.9-2.61.4-3.1-2.6-2.6-2.4-2.4-2.3-2.3-2.2-0.9
Distance traveled after self-admin5.87.110.51.5-2.7-2.3-3.0-2.72.0-3.11.8-2.5-3.1-3.0-3.0-3.0-3.2-3.2-3.10.7
Extensor digitorum longus weight5.120.226.25.1-4.6-4.6-4.6-4.75.0-4.65.0-4.7-4.5-4.6-4.7-4.5-4.2-4.3-4.3-0.1
Bone: elastic displacement6.47.410.6-3.32.93.12.93.0-2.42.8-3.03.02.62.72.72.62.52.42.50.8
Bone: elastic work2.22.86.4-2.22.02.11.71.90.01.5-2.32.11.41.51.41.10.90.90.92.5
Bone: endosteal estimation0.81.85.12.2-1.4-1.3-1.2-1.31.3-1.32.3-1.3-1.1-1.2-1.2-1.0-0.8-1.0-0.9-1.0
Bone: endosteal perimeter0.81.86.22.5-1.4-1.4-1.2-1.31.6-1.22.2-1.6-0.8-0.9-1.0-1.0-0.8-0.9-0.7-0.3
Epididymis fat weight0.20.71.40.7-0.8-0.7-0.9-0.90.8-0.90.5-0.9-0.9-0.8-0.9-0.8-1.0-1.2-0.90.3
Delta time in closed arm before/after self-admin0.10.10.5-0.20.10.6-0.10.10.5-0.20.20.4-0.3-0.3-0.3-0.2-0.4-0.4-0.40.7
Delta time in open arm before/after self-admin0.30.20.50.50.3-0.10.50.40.20.60.5-0.10.60.70.60.50.70.60.7-0.3
Diff in mean of infusions in LGA sessions0.20.31.1-0.50.61.00.40.80.40.20.40.90.30.30.30.00.10.00.11.0
Delay discount exponential model param0.40.40.70.4-0.7-0.6-0.7-0.60.7-0.70.2-0.2-0.7-0.7-0.7-0.8-0.8-0.8-0.80.2
Extinction: sum of active levers before priming2.22.43.5-1.71.51.31.61.6-1.91.6-1.11.11.71.81.81.61.71.61.8-0.3
Active lever presses in extinction session 60.00.00.20.1-0.20.2-0.20.20.2-0.1-0.10.4-0.1-0.0-0.10.0-0.2-0.2-0.1-0.5
Bone: final force2.23.56.22.1-1.8-1.8-1.9-1.82.5-2.01.5-1.7-1.9-1.8-1.9-1.9-1.9-1.8-1.80.7
Bone: final moment1.82.96.41.9-1.5-1.5-1.7-1.62.5-1.81.4-1.3-1.7-1.7-1.8-1.8-1.8-1.7-1.81.1
Food consumed during 24 hour testing period1.41.95.51.9-1.5-1.4-1.3-1.41.3-1.42.3-1.5-1.3-1.4-1.3-1.3-1.0-1.0-1.1-0.1
Glucose1.32.14.12.0-1.5-1.4-1.4-1.51.6-1.52.0-1.6-1.3-1.4-1.4-1.4-1.3-1.1-1.3-0.2
Heart weight0.71.13.11.7-0.9-0.8-0.9-0.81.7-1.01.7-0.5-1.0-0.9-1.0-0.9-0.7-1.0-0.7-0.4
Delay discount hyperbolic model param0.40.40.70.4-0.6-0.6-0.7-0.50.7-0.60.2-0.2-0.7-0.7-0.7-0.8-0.8-0.8-0.70.1
Intermittent access intake day 1-15 change0.30.53.31.0-0.3-0.3-0.4-0.21.3-0.61.8-0.3-0.5-0.6-0.5-0.7-0.6-0.5-0.50.5
Intermittent access intake escalation0.40.73.30.9-0.4-0.3-0.6-0.31.5-0.81.8-0.3-0.7-0.8-0.6-0.8-0.8-0.8-0.70.8
Intermittent access intake escalation 21.41.63.10.7-0.8-0.7-1.1-0.81.8-1.31.7-0.7-1.4-1.4-1.3-1.5-1.5-1.5-1.51.3
Intermitt. access day 1 inactive lever presses0.20.61.40.3-0.9-1.2-0.9-1.0-0.6-0.80.5-1.1-0.7-0.6-0.7-0.7-0.5-0.7-0.6-0.5
Intermitt. access day 15 inactive lever presses0.10.20.50.3-0.5-0.7-0.6-0.30.1-0.50.7-0.1-0.6-0.5-0.5-0.6-0.4-0.4-0.50.4
Intermitt. access escalation Index0.20.20.40.4-0.6-0.4-0.6-0.30.4-0.6-0.1-0.1-0.6-0.7-0.5-0.5-0.6-0.6-0.50.1
Intermittent access day 1 total infusions1.42.33.7-1.11.21.71.51.6-1.51.5-1.41.61.61.61.61.91.61.61.6-0.3
Intermittent access day 15 total infusions0.10.21.00.10.30.60.20.50.70.11.00.50.10.10.10.1-0.0-0.00.01.0
Intermittent access terminal intake (last 3 days)0.20.21.00.3-0.3-0.2-0.4-0.20.6-0.41.0-0.3-0.5-0.4-0.4-0.3-0.5-0.5-0.40.7
Intermittent access total infusions0.10.10.40.30.00.30.10.30.3-0.00.60.30.00.10.10.30.10.10.10.3
Intermittent access day 1 locomotion1.31.62.5-1.20.91.41.11.3-1.61.2-1.61.41.31.31.31.61.21.21.3-0.1
Intermittent access day 15 total locomotion1.32.33.5-1.01.41.91.51.8-1.21.5-0.71.81.71.61.71.71.71.61.70.2
Intermittent access total locomotion1.11.42.8-1.21.21.71.11.5-0.81.1-1.11.71.11.11.11.20.90.81.00.9
Intermittent access standard deviation0.10.11.50.1-0.2-0.1-0.1-0.1-0.2-0.21.2-0.3-0.1-0.10.0-0.10.00.0-0.0-0.1
Left kidney weight0.73.29.93.1-2.4-2.0-2.0-1.91.5-1.81.9-1.8-1.7-1.7-1.6-1.3-1.0-1.3-1.0-1.4
Right kidney weight0.41.87.52.7-1.3-1.1-1.1-1.12.2-1.11.9-0.9-1.0-1.1-1.1-0.9-0.6-1.0-0.7-0.8
Cocaine induced anxiety0.60.91.90.4-1.1-1.3-1.0-1.3-0.0-0.8-0.5-1.4-1.0-0.8-1.0-0.7-0.9-1.0-0.9-1.0
Post-drug Anxiety2.83.06.31.6-2.0-2.3-1.9-2.20.9-1.70.6-2.5-1.6-1.6-1.7-1.5-1.5-1.4-1.5-1.7
Baseline Anxiety0.91.02.41.1-0.8-0.7-0.9-0.81.3-1.11.5-0.8-0.9-1.0-0.9-1.2-1.1-0.8-1.1-0.1
Tail length1.55.88.62.9-2.6-2.5-2.6-2.52.5-2.52.7-2.1-2.4-2.4-2.5-2.3-2.1-2.2-2.3-1.0
Length with tail1.14.711.03.3-2.7-2.7-2.3-2.51.6-2.22.5-2.6-1.8-1.8-1.9-1.7-1.3-1.3-1.4-2.0
Length without tail0.10.41.31.1-0.6-0.7-0.2-0.6-0.3-0.10.6-1.10.10.10.10.20.60.60.5-1.1
Times rat made contact with spout0.50.60.90.2-0.8-0.7-0.9-0.80.7-0.90.1-0.9-0.8-0.9-0.9-0.9-0.9-1.0-0.9-0.1
Lifetime Intake0.10.11.00.5-0.10.10.00.20.2-0.01.00.20.10.10.10.30.20.20.2-0.3
Liver weight, left0.20.41.11.1-0.7-0.6-0.5-0.60.6-0.50.9-0.6-0.6-0.6-0.6-0.3-0.3-0.3-0.5-0.4
Liver weight, right0.50.91.6-0.51.01.31.11.1-0.11.0-0.41.21.01.00.90.91.11.00.9-0.9
Locomotor activity0.10.10.3-0.30.30.50.30.3-0.20.2-0.50.30.30.30.30.10.10.30.20.6
Locomotor testing distance0.10.20.6-0.00.10.50.30.3-0.80.3-0.10.20.50.50.60.40.50.60.6-0.5
Locomotor testing rearing0.30.51.70.9-0.9-0.6-0.7-0.80.4-0.81.3-0.6-0.6-0.7-0.6-0.8-0.5-0.5-0.6-0.3
Locomotion in novel chamber0.50.61.4-0.0-0.9-0.4-1.0-0.80.3-0.9-0.6-0.5-0.9-1.0-1.0-0.8-1.2-1.0-1.20.2
Locomotion in novel chamber post-restriction2.64.26.81.5-2.0-1.1-2.3-1.72.5-2.31.4-0.8-2.4-2.3-2.4-2.2-2.6-2.5-2.41.2
Fecal boli incidents, locomotor time 12.84.16.3-1.52.52.12.42.2-1.22.3-0.41.92.42.52.32.12.12.22.20.0
Change in fecal boli incidents, locomotor task1.41.43.30.7-1.8-1.3-1.6-1.1-0.2-1.5-0.2-0.6-1.4-1.5-1.2-1.0-1.3-1.2-1.2-0.1
Time >=10cm from walls, locomotor time 10.10.21.10.2-0.1-0.2-0.0-0.0-0.40.1-0.90.10.10.20.20.40.20.30.3-1.0
Bouts of movement, locomotor time 11.21.42.6-1.41.61.11.51.2-1.21.2-0.60.81.31.41.21.11.11.01.10.2
Total resting periods, locomotor time 12.22.44.5-1.82.11.72.01.7-1.11.6-1.11.41.71.71.51.41.41.31.40.7
Rest time, locomotor task time 11.01.32.7-1.41.51.61.21.20.41.1-1.61.40.80.90.70.60.40.50.41.7
Distance moved, locomotor task time 10.81.24.21.2-1.4-1.8-1.0-1.3-0.4-0.91.1-1.8-0.6-0.8-0.6-0.7-0.3-0.3-0.3-2.0
Vertical activity count, locomotor time 10.51.23.51.2-1.6-1.9-1.2-1.3-0.6-1.00.6-1.8-0.8-0.9-0.7-0.5-0.3-0.4-0.4-1.5
Time >=10cm from walls, locomotor time 20.20.41.1-0.20.3-0.40.5-0.1-0.80.6-0.4-0.40.60.70.40.60.80.80.7-1.1
Bouts of movement, locomotor time 21.11.87.81.4-1.4-0.9-1.3-0.81.4-1.42.8-0.6-1.3-1.4-1.1-1.2-1.3-1.3-1.2-0.5
Total resting periods, locomotor time 20.61.05.41.1-1.0-0.5-0.9-0.41.2-1.02.3-0.1-0.9-1.0-0.8-0.9-1.0-0.9-0.9-0.3
Rest time, locomotor task time 20.50.62.0-1.10.81.20.70.9-0.40.7-1.41.00.50.70.60.60.40.60.50.1
Distance moved, locomotor task time 20.00.00.2-0.00.3-0.40.2-0.20.20.10.0-0.50.20.1-0.0-0.20.0-0.0-0.10.3
Vertical activity count, locomotor time 20.10.21.20.7-0.2-1.1-0.1-0.60.0-0.10.4-1.00.00.0-0.2-0.10.00.1-0.0-0.4
Light reinforcement 10.81.96.92.6-1.5-1.5-1.0-1.20.6-1.02.6-1.9-0.7-0.8-0.7-0.7-0.2-0.5-0.3-2.1
Light reinforcement 20.61.04.91.9-1.2-1.2-0.7-0.9-0.1-0.51.2-1.3-0.4-0.4-0.2-0.10.20.10.2-2.2
Bone: marrow area0.91.95.22.1-1.4-1.3-1.3-1.31.5-1.42.3-1.3-1.2-1.3-1.3-1.2-0.9-1.1-1.0-0.7
Bone: maximum diameter3.46.312.03.0-2.4-2.2-2.6-2.33.5-2.63.0-2.1-2.4-2.4-2.6-2.5-2.6-2.6-2.40.7
Bone: maximum force4.27.512.43.1-2.6-2.7-2.8-2.73.5-2.92.4-2.6-2.8-2.8-2.8-2.9-2.7-2.7-2.81.0
Bone: maximum moment3.66.211.82.8-2.3-2.3-2.5-2.43.4-2.62.2-2.2-2.6-2.6-2.6-2.6-2.5-2.5-2.61.3
Mean time between licks in bursts0.20.51.2-0.10.70.90.70.8-0.20.7-0.01.10.60.50.70.80.80.70.6-1.1
Mean num. licks in bursts3.14.85.6-2.12.32.22.32.3-2.12.3-1.92.22.32.42.32.32.32.22.3-0.7
Cd content in liver2.12.33.91.7-1.4-1.3-1.5-1.42.0-1.61.9-1.3-1.6-1.7-1.6-1.5-1.5-1.5-1.60.5
Co content in liver0.70.94.90.10.60.70.80.8-0.60.80.00.60.90.80.91.01.11.00.9-2.2
Cu content in liver1.11.32.2-1.01.41.11.31.1-0.61.2-1.51.01.31.21.11.11.11.11.0-0.4
Fe content in liver0.81.02.3-0.00.70.70.90.8-1.01.0-0.20.61.11.11.11.31.21.31.3-1.5
K content in liver0.40.41.2-0.30.50.30.50.5-0.80.5-0.50.30.60.60.60.70.70.60.7-1.1
Mg content in liver1.31.42.1-0.91.11.01.21.1-1.01.2-1.31.01.21.21.11.21.31.21.2-1.4
Mn content in liver2.52.83.81.2-1.4-1.5-1.6-1.71.9-1.71.8-1.5-1.8-1.7-1.8-1.9-1.8-1.8-1.9-0.6
Na content in liver0.80.91.4-1.01.21.11.11.1-0.61.0-0.71.21.01.00.91.00.80.80.9-0.2
Rb content in liver5.46.37.6-2.22.52.52.72.6-2.52.8-1.92.62.72.82.72.72.72.72.7-0.2
Se content in liver3.13.75.41.4-1.7-1.8-1.9-2.12.0-1.91.9-2.1-2.0-2.0-2.1-2.3-2.1-2.0-2.20.2
Sr content in liver0.40.40.60.4-0.6-0.8-0.6-0.80.6-0.60.1-0.8-0.6-0.6-0.7-0.7-0.5-0.5-0.60.6
Zn content in liver0.00.00.30.10.1-0.0-0.0-0.10.6-0.1-0.3-0.2-0.0-0.0-0.2-0.2-0.1-0.3-0.2-0.1
Bone: minimum diameter0.10.20.70.20.40.50.30.40.80.20.40.60.20.20.10.10.20.10.10.8
Time in familiar zone, hab. session 10.40.41.1-1.10.70.80.20.41.1-0.0-0.40.6-0.3-0.2-0.3-0.5-0.6-1.0-0.70.7
Time in novel zone, hab. session 12.62.65.2-0.10.80.81.31.2-2.01.5-1.01.01.81.71.92.02.02.32.2-1.8
Total zone transitions, hab. session 10.10.21.3-0.80.10.20.10.1-0.80.1-1.2-0.20.20.20.30.10.00.20.20.5
Total locomotion distance, hab. session 10.71.02.1-0.4-0.7-0.5-1.0-0.80.7-1.1-0.4-0.7-1.0-1.0-1.0-1.3-1.5-1.3-1.31.2
Locomotion velocity, hab. session 11.72.44.00.5-1.4-1.3-1.7-1.61.4-1.70.5-1.5-1.6-1.6-1.6-1.9-2.0-1.7-1.81.4
Time in familiar zone, hab. session 20.60.71.7-1.01.21.20.91.00.50.8-0.61.10.50.60.50.40.40.10.31.3
Time in novel zone, hab. session 21.11.23.3-0.30.40.40.70.7-1.80.9-1.00.61.11.01.21.31.21.41.3-1.6
Total zone transitions, hab. session 20.81.06.10.7-1.3-1.2-1.1-1.0-0.6-0.90.4-1.0-0.6-0.6-0.6-0.6-0.6-0.7-0.3-2.5
Total locomotion distance, hab. session 21.11.42.10.9-1.4-1.3-1.5-1.40.8-1.40.8-1.2-1.2-1.2-1.2-1.3-1.3-1.3-1.1-0.6
Locomotion velocity, hab. session 21.21.52.20.9-1.5-1.3-1.5-1.40.9-1.40.8-1.4-1.2-1.2-1.2-1.4-1.4-1.3-1.2-0.5
Novel to familiar place preference ratio4.85.27.1-1.71.91.92.22.1-2.72.4-2.32.02.62.62.52.62.62.62.60.3
Novelty place preference6.06.48.4-2.12.22.22.52.4-2.92.7-2.82.32.82.82.72.92.82.82.80.4
Time in novel zone, NPP test7.07.59.9-2.22.42.42.72.6-3.12.9-2.92.53.03.03.03.13.03.03.10.5
Total zone transitions, NPP test0.60.91.90.9-1.4-1.2-1.2-1.1-0.2-1.10.2-0.9-1.0-1.0-0.9-0.8-0.8-0.9-0.7-1.1
Total locomotion distance, NPP test1.82.44.11.4-2.0-1.7-1.9-1.70.6-1.81.1-1.6-1.7-1.8-1.5-1.6-1.5-1.6-1.4-0.6
Locomotion velocity, NPP test2.13.04.51.5-2.1-1.9-2.1-1.90.9-2.01.2-1.8-1.9-1.9-1.7-1.8-1.7-1.8-1.6-0.7
Intraocular pressure1.42.03.41.8-1.6-1.7-1.5-1.61.4-1.50.8-1.6-1.4-1.5-1.4-1.4-1.2-1.1-1.3-0.2
Delta distance traveled before/after self-admin0.40.40.80.3-0.50.0-0.7-0.20.8-0.90.7-0.1-0.8-0.7-0.7-0.7-0.9-0.8-0.90.3
Delta ambulatory time before/after self-admin0.50.61.3-0.1-0.70.2-0.9-0.10.4-1.00.30.2-1.0-1.0-0.8-0.7-1.2-1.1-1.00.3
Parametrial fat weight0.20.53.2-0.0-0.10.20.20.4-1.10.30.40.50.60.40.60.60.70.70.7-1.8
Pavlov. Cond. lever latency7.19.011.9-3.33.43.33.33.4-2.43.2-3.03.43.03.03.02.92.82.82.71.1
Pavlov. Cond. magazine entry latency0.40.51.41.2-0.8-0.7-0.7-0.70.9-0.60.6-0.6-0.6-0.5-0.6-0.5-0.5-0.5-0.4-0.8
Pavlov. Cond. change in total contacts2.02.13.71.5-1.9-1.8-1.8-1.70.6-1.61.5-1.6-1.5-1.4-1.4-1.3-1.3-1.4-1.1-0.9
Pavlov. Cond. index score3.24.15.32.3-2.3-2.2-2.2-2.31.9-2.11.8-2.2-2.0-1.9-2.0-1.9-1.9-1.9-1.8-1.2
Pavlov. Cond. latency score2.93.74.92.2-2.1-2.1-2.1-2.21.8-2.01.8-2.1-1.9-1.8-1.9-1.8-1.8-1.7-1.6-1.3
Pavlov. Cond. lever contacts6.77.910.83.0-3.2-3.2-3.1-3.32.3-3.02.7-3.3-2.8-2.8-2.9-2.8-2.7-2.6-2.5-1.0
Pavlov. Cond. magazine entry number0.50.61.1-1.00.90.80.90.9-1.00.8-0.50.60.70.60.80.70.80.80.60.7
Pavlov. Cond. intertrial magazine entries0.10.20.40.2-0.3-0.3-0.3-0.30.3-0.40.5-0.2-0.5-0.6-0.5-0.5-0.3-0.6-0.60.3
Pavlov. Cond. lever-magazine prob. diff.3.03.84.72.1-2.1-2.1-2.1-2.22.0-2.01.7-2.1-1.9-1.8-2.0-1.9-1.9-1.9-1.8-1.0
Pavlov. Cond. response bias3.64.56.02.5-2.5-2.4-2.4-2.41.8-2.22.0-2.3-2.1-2.0-2.1-2.0-2.0-2.0-1.8-1.1
Pavlov. Cond. lever latency1.62.16.5-1.60.91.31.11.3-2.51.3-1.71.31.21.31.51.51.31.41.5-1.3
Pavlov. Cond. magazine entry latency0.30.30.7-0.20.90.60.70.60.50.6-0.10.50.60.50.50.50.50.50.40.8
Pavlov. Cond. change in total contacts0.40.73.80.30.0-0.2-0.3-0.41.9-0.50.8-0.4-0.5-0.5-0.7-0.8-0.8-0.7-0.81.9
Pavlov. Cond. index score0.30.33.10.30.4-0.00.2-0.01.40.00.5-0.1-0.0-0.1-0.2-0.3-0.2-0.2-0.31.7
Pavlov. Cond. latency score0.40.53.40.30.2-0.20.0-0.21.6-0.20.7-0.2-0.2-0.2-0.4-0.5-0.4-0.4-0.51.8
Pavlov. Cond. lever contacts1.21.66.01.4-0.7-1.1-0.9-1.12.4-1.01.5-1.1-1.0-1.1-1.2-1.3-1.1-1.1-1.31.3
Pavlov. Cond. magazine entry number0.20.32.30.1-0.4-0.1-0.1-0.0-1.20.0-0.10.00.10.10.20.30.30.40.4-1.5
Pavlov. Cond. intertrial magazine entries0.20.30.60.5-0.7-0.8-0.7-0.70.1-0.60.7-0.4-0.5-0.5-0.5-0.5-0.5-0.4-0.5-0.4
Pavlov. Cond. lever-magazine prob. diff.0.30.43.50.20.40.00.2-0.01.5-0.00.5-0.1-0.0-0.1-0.3-0.3-0.3-0.3-0.41.9
Pavlov. Cond. response bias0.50.74.00.8-0.1-0.6-0.3-0.62.0-0.50.7-0.6-0.5-0.6-0.8-0.8-0.7-0.7-0.91.4
Time in closed arm before self-admin0.40.51.0-0.50.80.70.90.8-0.20.8-0.70.70.70.80.80.70.91.00.70.5
Time in closed arm after self-admin0.20.20.8-0.80.40.90.20.4-0.20.2-0.60.70.10.10.20.1-0.00.00.00.8
Time in open arm before self-admin0.70.72.00.4-1.3-1.2-1.0-1.2-0.8-0.80.1-1.2-0.7-0.6-0.7-0.4-0.5-0.5-0.5-1.4
Time in open arm after self-admin0.80.92.31.3-1.1-1.3-0.8-0.90.6-0.71.5-1.4-0.7-0.6-0.7-0.6-0.5-0.5-0.5-1.0
Bone: periosteal estimation2.24.68.52.7-2.1-1.9-2.1-2.02.8-2.22.9-1.8-2.1-2.1-2.1-2.1-2.0-2.1-2.00.0
Bone: periosteal perimeter0.91.55.02.2-1.2-1.1-1.1-1.01.8-1.12.2-1.0-0.9-0.9-1.0-0.9-0.8-0.8-0.7-0.2
Bone: post-yield work2.73.98.83.0-2.0-1.9-1.9-2.12.3-1.92.5-2.2-1.9-1.9-1.9-1.7-1.5-1.6-1.7-0.9
Progressive ratio test 1 active lever presses0.20.20.60.00.20.20.40.4-0.50.5-0.20.20.50.60.60.80.70.60.7-0.4
Progressive ratio test 1 breakpoint0.10.10.40.10.10.10.30.3-0.40.3-0.10.10.40.40.50.60.50.40.6-0.4
Progressive ratio test 1 inactive lever presses0.30.51.21.0-0.9-1.1-0.6-0.6-0.1-0.61.1-0.8-0.4-0.3-0.3-0.2-0.1-0.2-0.1-1.1
Progressive ratio test 2 active lever presses0.60.71.20.00.50.60.80.9-0.60.70.60.70.80.90.91.11.11.11.1-0.8
Progressive ratio test 2 breakpoint0.60.71.40.00.60.70.80.9-0.60.80.60.70.91.01.01.11.21.11.1-0.8
Progressive ratio test 2 inactive lever presses0.00.10.80.3-0.3-0.1-0.20.0-0.0-0.30.90.2-0.1-0.1-0.00.00.00.1-0.0-0.1
Incentive Sensitization - Responses0.20.20.60.20.20.30.30.5-0.20.30.70.50.40.50.40.60.60.60.5-0.6
Incentive Sensitization - Breakpoint0.30.40.70.10.40.50.50.7-0.30.40.70.70.50.60.60.70.80.80.7-0.5
Sum of active levers in priming session hrs 5-64.94.57.5-1.11.81.72.22.0-2.12.3-0.61.32.52.52.52.42.72.72.6-1.5
Progressive ratio0.10.21.50.20.10.20.20.3-0.10.11.20.30.20.20.30.20.30.30.4-0.4
Food seeking constrained by brief footshock7.49.015.83.9-3.4-4.0-3.1-3.62.4-2.93.8-3.4-2.7-2.8-2.8-2.6-2.1-2.1-2.3-1.7
Seeking ratio, punishment vs. effort2.23.15.82.0-2.0-2.4-1.8-2.31.6-1.71.3-2.1-1.8-1.8-1.9-1.7-1.5-1.5-1.6-0.3
Retroperitoneal fat weight0.31.34.0-1.71.11.61.01.5-1.20.9-1.32.00.90.80.91.10.60.50.60.6
Reaction time number correct0.10.20.50.10.20.20.40.3-0.50.5-0.20.10.50.50.40.60.70.60.50.1
Reaction time mean minus median0.30.84.8-0.40.50.70.10.11.9-0.30.60.6-0.4-0.4-0.6-0.8-0.9-1.0-0.92.2
Reaction time mean minus median AUC0.51.24.70.2-0.20.0-0.6-0.52.2-0.91.2-0.2-1.0-0.9-1.1-1.2-1.3-1.3-1.31.9
Reaction time num false alarms0.30.41.20.10.00.2-0.3-0.11.1-0.50.20.2-0.6-0.5-0.6-0.6-0.8-0.9-0.81.0
Reaction time num false alarms AUC0.50.81.90.8-0.6-0.4-0.8-0.61.4-1.00.7-0.4-1.0-1.0-1.0-1.0-1.1-1.2-1.20.5
Reaction time trials correct on left0.10.20.50.10.20.20.40.3-0.50.5-0.20.10.50.50.40.60.70.60.50.1
Reaction time trials on left0.10.30.60.00.30.30.50.4-0.50.6-0.30.30.60.60.50.70.80.70.60.2
Reaction time mean1.11.86.2-1.61.72.21.31.60.41.0-1.22.00.91.00.90.80.40.40.52.5
Reaction time mean AUC1.22.06.3-1.71.82.31.41.60.51.1-1.32.01.01.10.90.80.50.50.62.5
Median of all reaction times1.92.86.2-1.91.92.51.72.0-0.41.5-1.82.31.41.51.51.41.11.01.22.0
Reaction time omissions2.13.05.7-1.01.92.41.92.1-0.61.8-1.22.21.91.81.91.81.81.81.7-0.3
Reaction time false alarm rate0.30.41.00.1-0.20.1-0.4-0.21.0-0.60.00.1-0.7-0.6-0.6-0.7-0.9-1.0-0.80.6
Reaction time premature initiation rate4.05.59.0-2.63.02.62.72.6-1.72.4-2.02.42.52.42.42.22.12.12.01.6
Reaction time premature initiations3.05.37.9-2.32.82.52.72.4-1.82.5-1.82.22.52.42.42.32.22.32.01.5
Std. dev. reaction times0.50.95.7-1.21.21.50.80.91.10.4-0.61.20.30.40.2-0.0-0.2-0.2-0.22.4
Reaction time trials completed0.10.30.60.00.30.30.50.4-0.50.6-0.30.30.60.60.50.70.80.70.60.2
Reaction time trials AUC0.10.30.6-0.10.30.30.50.4-0.60.6-0.30.30.60.60.50.70.80.70.60.3
Run reversals in cocaine runway, females0.30.31.6-0.8-0.20.4-0.40.2-0.1-0.4-0.10.5-0.5-0.5-0.4-0.4-0.6-0.5-0.61.3
Run reversals in cocaine runway, males0.20.20.7-0.70.60.40.50.3-0.60.5-0.80.50.60.60.40.20.40.40.3-0.0
Latency to leave start box in cocaine runway1.51.72.51.0-1.4-1.3-1.4-1.31.0-1.40.3-1.4-1.4-1.4-1.4-1.4-1.5-1.6-1.40.3
Latency to leave start box in cocaine runway, F0.10.10.30.20.00.00.20.2-0.40.2-0.5-0.10.30.30.40.40.30.20.4-0.5
Latency to leave start box in cocaine runway, M5.55.16.91.5-2.6-2.5-2.6-2.51.3-2.61.2-2.5-2.6-2.6-2.5-2.4-2.5-2.5-2.40.1
Std. dev. time between licks in bursts0.60.81.2-0.61.11.01.11.1-0.21.0-0.81.11.00.91.01.00.90.70.8-0.7
Total sessions with >9 infusions0.10.11.50.7-0.3-0.1-0.1-0.00.2-0.01.2-0.10.1-0.00.10.20.20.20.1-0.3
Short access day 1 total inactive lever presses0.60.93.00.7-1.3-1.3-1.0-1.0-0.8-0.81.5-1.0-0.6-0.6-0.5-0.3-0.2-0.3-0.3-1.7
Short access day 10 total inactive lever presses0.30.71.60.3-0.8-1.2-0.9-1.0-0.1-0.90.9-1.0-0.7-0.8-0.9-1.1-0.8-0.6-0.90.1
Short access day 1 total infusions0.20.31.80.6-0.7-0.5-0.3-0.2-0.4-0.31.3-0.3-0.1-0.10.00.10.20.20.2-1.1
Short access day 10 total infusions0.40.51.1-0.10.30.40.60.6-0.80.7-0.00.40.80.80.91.10.90.91.0-0.4
Short access total infusions0.30.30.80.40.00.20.40.4-0.40.40.90.20.60.50.60.80.70.70.7-0.8
Short access day 1 locomotion1.51.82.8-1.31.11.61.31.5-1.71.3-0.21.51.41.41.41.61.41.31.50.0
Short access day 10 total locomotion0.61.23.2-1.51.31.81.01.5-0.50.9-0.71.50.80.90.80.80.50.30.61.6
Short access total locomotion0.70.91.7-0.90.91.30.91.1-1.00.9-0.51.01.01.01.01.10.90.81.00.4
One hour access (0.3 mA shock)0.50.51.10.30.60.40.70.7-0.00.70.40.60.80.80.80.91.01.10.9-0.5
Compulsive drug intake0.10.10.5-0.20.50.10.40.30.30.5-0.40.20.50.20.30.10.20.40.10.7
One hour access (shock baseline)0.30.41.70.50.20.20.50.4-0.50.40.80.30.60.60.60.81.00.80.9-1.3
Social response proportion1.01.11.8-1.31.10.81.11.0-1.11.1-1.11.31.01.11.01.00.90.91.0-0.9
Social responses0.30.41.60.8-0.5-0.8-0.5-0.70.6-0.51.0-0.5-0.4-0.4-0.6-0.6-0.4-0.5-0.4-1.2
Social time0.40.62.30.50.70.40.80.50.10.70.70.50.70.70.70.80.90.70.8-1.5
Soleus weight0.20.72.91.6-0.2-0.30.3-0.0-0.30.50.8-0.40.70.60.60.91.11.21.0-1.7
Bone: stiffness5.59.012.33.2-2.9-3.0-3.1-3.03.5-3.22.9-2.7-3.1-3.1-3.2-3.2-3.1-3.0-3.10.3
Tibialis anterior weight7.123.933.75.8-5.2-5.3-5.1-5.44.9-5.05.2-5.5-4.9-5.0-5.0-4.7-4.4-4.5-4.5-0.7
Time to tail flick, vehicle, before self-admin1.31.42.6-0.91.31.61.31.5-0.61.2-1.11.31.31.41.31.01.11.11.10.5
Time to tail flick, vehicle, after self-admin0.30.41.50.7-0.2-0.1-0.30.11.2-0.51.20.7-0.4-0.4-0.5-0.5-0.5-0.6-0.50.8
Time to tail flick, test, before self-admin0.50.50.70.5-0.8-0.8-0.8-0.60.6-0.80.7-0.3-0.8-0.7-0.7-0.7-0.8-0.8-0.70.2
Time to tail flick, test, after self-admin0.40.42.80.50.2-0.2-0.1-0.41.7-0.2-0.4-0.1-0.4-0.4-0.8-0.5-0.6-0.6-0.91.0
Delta time to tail flick, vehicle, before/after SA1.11.12.61.2-1.0-1.0-1.0-0.81.3-1.11.6-0.4-1.1-1.1-1.1-0.9-1.0-1.0-1.0-0.2
Delta time to tail flick, test, before/after SA0.50.61.3-0.51.20.91.00.70.30.9-0.90.60.80.70.50.70.70.70.40.7
Tibia length0.41.03.31.8-1.2-1.2-1.0-1.00.6-1.01.6-1.0-0.9-0.9-0.8-0.5-0.4-0.4-0.5-0.8
Ambulatory time before self-admin2.94.38.71.6-2.6-2.7-2.4-2.70.5-2.21.5-2.9-2.2-2.2-2.0-1.9-1.9-1.8-1.7-1.0
Ambulatory time after self-admin4.65.58.01.5-2.6-2.1-2.7-2.41.1-2.81.8-2.5-2.8-2.7-2.4-2.4-2.7-2.6-2.4-0.5
Bone: tissue strength0.40.45.10.4-0.2-0.3-0.3-0.30.6-0.3-0.5-0.3-0.5-0.4-0.4-0.3-0.4-0.4-0.42.3
Total heroin consumption1.61.93.3-0.61.20.71.51.2-1.21.5-0.70.91.71.61.61.51.71.81.7-1.0
Bone: trabecular number1.01.62.40.9-0.9-1.3-1.1-1.31.5-1.20.7-1.2-1.4-1.4-1.4-1.4-1.3-1.4-1.5-1.3
Bone: trabecular spacing0.30.42.70.2-0.3-0.3-0.4-0.30.7-0.40.40.1-0.5-0.5-0.6-0.5-0.6-0.6-0.61.6
Bone: trabecular thickness0.20.21.1-0.70.30.30.20.3-0.50.2-1.00.30.20.20.30.20.10.30.2-1.1
Bone: trabecular tissue density4.66.89.02.0-2.8-2.6-3.0-2.81.9-3.02.3-2.5-2.9-2.9-2.8-2.8-2.9-2.7-2.7-1.1
Water consumed over 24 hours1.82.42.91.6-1.7-1.7-1.7-1.71.5-1.71.2-1.7-1.6-1.6-1.6-1.6-1.5-1.5-1.5-0.4
Number of responses in last shaping day0.80.95.11.5-0.8-0.6-0.1-0.4-0.50.11.2-1.00.40.30.40.61.01.00.9-2.3