Hub : Genes

Rab27a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Rab27a 0.11 0.06 1.9e-10 0.08 0.06 0.07 0.08 8.3e-09 1.1e-07 2.2e-08 6.9e-09
2 OFC gene expression Rab27a 0.33 0.14 9.1e-04 0.11 0.05 0.01 0.07 1.3e-03 3.0e-02 2.2e-01 1.0e-02
3 Brain gene expression Rab27a 0.15 0.07 3.5e-13 0.16 0.14 0.14 0.16 5.3e-15 3.4e-13 1.5e-12 1.8e-14
4 BLA gene expression Rab27a 0.41 0.11 0.0e+00 0.34 0.32 0.35 0.37 3.2e-19 2.3e-17 8.8e-20 8.9e-21
5 PL gene expression Rab27a 0.25 0.08 0.0e+00 0.3 0.29 0.31 0.31 2.7e-33 4.4e-32 5.8e-35 1.5e-34
6 IL gene expression Rab27a 0.33 0.15 7.3e-05 0.22 0.1 0.17 0.19 4.5e-06 2.0e-03 7.6e-05 3.1e-05
7 NAcc gene expression Rab27a 0.09 0.04 4.2e-10 0.09 0.09 0.08 0.09 1.1e-10 3.3e-10 1.2e-09 3.9e-10

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density0.10.20.3-0.20.30.3-0.40.40.50.5
Area under the delay curve0.00.00.1-0.4-0.0-0.1-0.0-0.0-0.20.1
BMI with tail7.022.726.03.6-5.0-4.94.7-4.8-5.1-5.1
BMI without tail3.87.89.81.3-2.8-2.92.9-2.9-3.1-3.1
Body weight3.313.815.53.3-3.9-3.93.7-3.8-3.7-3.7
Weight adjusted by age5.86.57.72.4-2.5-2.52.6-2.5-2.8-2.7
Bone surface0.20.40.70.8-0.6-0.60.6-0.6-0.5-0.6
Bone volume0.20.40.70.9-0.6-0.60.6-0.5-0.5-0.5
Breakpoint value in progressive ratio session0.00.00.1-0.3-0.2-0.20.2-0.20.00.0
Number of licking bursts2.02.42.6-1.61.61.6-1.51.61.41.4
Context. condit. distance diff. score0.20.20.3-0.40.40.4-0.50.50.50.5
Locomotion velocity, session 11.51.61.91.1-1.4-1.41.4-1.3-1.1-1.1
Locomotion distance, session 10.10.10.5-0.70.10.1-0.10.10.20.1
Locomotion velocity, session 20.20.20.3-0.3-0.6-0.60.4-0.6-0.3-0.4
Locomotion distance, session 20.71.01.4-0.2-1.2-1.21.1-1.1-1.0-1.0
Locomotion velocity, session 30.20.20.4-0.2-0.6-0.60.6-0.6-0.3-0.3
Locomotion distance, session 31.82.03.4-1.81.31.3-1.31.31.31.3
Stereotopy head waving bouts, day 30.40.51.61.3-0.7-0.70.7-0.6-0.3-0.2
Stereotopy head waving duration, day 31.01.23.31.8-1.1-1.11.1-1.1-0.6-0.5
Locomotion velocity, session 70.70.80.9-1.00.90.9-0.90.90.80.8
Locomotion distance, session 70.70.91.6-1.30.80.8-0.80.80.90.9
Stereotopy head waving bouts, day 71.11.21.70.9-1.3-1.31.3-1.3-0.8-0.8
Stereotopy head waving duration, day 71.31.62.01.0-1.3-1.31.4-1.4-1.1-1.1
Locomotion velocity, session 80.60.70.90.5-0.9-0.90.9-0.9-0.7-0.7
Locomotion distance, session 80.10.21.4-1.2-0.0-0.0-0.1-0.00.20.2
Degree of sensitization distance0.00.00.00.10.10.1-0.10.00.20.2
Degree of sensitization stereotypy1.21.31.70.7-1.3-1.31.3-1.3-1.0-1.0
Conditioned locomotion0.10.10.2-0.0-0.3-0.40.2-0.3-0.3-0.3
Cocaine response after cond. corrected4.75.38.93.0-2.2-2.12.2-2.1-2.2-2.2
Cocaine response after cond. not corrected3.03.46.72.6-1.7-1.71.7-1.6-1.7-1.8
Cocaine response before conditioning1.11.32.3-1.51.11.1-1.11.11.01.0
Saline control response0.10.10.60.80.10.1-0.00.00.40.4
Bone: connectivity density0.81.31.5-1.21.11.1-1.01.11.21.2
Bone: cortical apparent density0.50.70.8-0.80.90.9-0.90.90.80.8
Bone: cortical area0.30.53.21.8-0.2-0.20.2-0.2-0.3-0.3
Bone: cortical porosity0.91.01.3-0.71.01.0-1.11.01.11.1
Bone: cortical porosity1.82.02.3-1.21.41.4-1.51.51.41.4
Bone: cortical thickness0.81.31.60.11.21.2-1.21.31.21.2
Bone: cortical thickness0.60.71.00.11.01.0-0.91.00.70.8
Bone: cortical tissue density0.60.70.8-0.90.90.9-0.90.90.80.8
Condit. Reinf. active minus inactive responses0.60.62.9-1.70.50.4-0.60.50.40.4
Condit. Reinf. active-inactive response ratio1.11.21.7-0.71.21.1-1.31.21.01.0
Condit. Reinf. active responses0.40.52.7-1.7-0.4-0.40.3-0.4-0.3-0.4
Condit. Reinf. inactive responses1.31.51.9-1.0-1.3-1.31.3-1.4-1.1-1.1
Incentive salience index mean0.30.42.5-1.60.20.1-0.40.20.20.1
Condit. Reinf. lever presses0.20.31.9-1.4-0.1-0.1-0.1-0.1-0.1-0.2
Condit. Reinf. active minus inactive responses2.43.03.41.8-1.8-1.81.7-1.7-1.6-1.6
Condit. Reinf. active-inactive response ratio1.61.73.61.9-1.1-1.21.1-1.2-1.1-1.2
Condit. Reinf. active responses1.41.92.51.1-1.5-1.61.4-1.4-1.3-1.3
Condit. Reinf. inactive responses0.20.21.2-1.10.00.1-0.10.10.40.5
Condit. Reinf. lever presses0.50.71.00.00.80.8-0.90.91.01.0
Condit. Reinf. lever reinforcers received0.91.21.71.0-1.2-1.31.1-1.2-0.9-0.9
Conditioned reinforcement - actives0.10.10.10.1-0.1-0.20.2-0.3-0.3-0.4
Conditioned reinforcement - inactives0.10.10.40.7-0.0-0.10.1-0.2-0.2-0.1
Conditioned locomotion0.40.40.6-0.70.80.7-0.80.70.40.5
Patch foraging indifference point 0 sec0.10.20.40.0-0.4-0.30.4-0.4-0.6-0.4
Patch foraging indifference point AUC0.60.73.8-2.00.20.4-0.40.40.60.5
Delay disc. indifference point, 0s delay0.70.82.7-1.60.70.6-0.70.70.70.7
Delay disc. indifference point, 16s delay0.20.20.4-0.30.50.5-0.50.50.30.6
Delay disc. indifference point, 2s delay0.10.10.1-0.30.30.3-0.30.30.20.2
Delay disc. indifference point, 24s delay0.20.20.5-0.40.40.4-0.40.30.40.7
Delay disc. indifference point, 4s delay0.30.30.7-0.80.50.5-0.60.60.30.5
Delay disc. indifference point, 8s delay0.50.50.8-0.0-0.8-0.80.7-0.8-0.9-0.5
Indifference point function ln k0.91.34.72.2-0.6-0.80.8-0.9-1.1-1.1
Indifference point function log k0.91.34.72.2-0.6-0.80.8-0.9-1.1-1.1
Patch foraging total patch changes 0 sec0.20.30.60.3-0.6-0.50.6-0.5-0.8-0.6
Patch foraging total patch changes 12 sec0.20.31.1-1.00.20.4-0.30.40.50.5
Patch foraging total patch changes 18 sec0.00.10.2-0.40.00.2-0.10.20.20.3
Patch foraging total patch changes 24 sec0.10.10.8-0.9-0.00.10.1-0.0-0.10.1
Patch foraging total patch changes 6 sec0.30.51.2-1.1-0.6-0.50.6-0.5-0.8-0.6
Patch foraging time to switch 0 sec0.71.11.5-0.71.21.1-1.11.20.90.9
Patch foraging water rate 0 sec1.82.93.21.8-1.7-1.71.7-1.7-1.7-1.6
Patch foraging water rate 12 sec3.14.76.32.5-2.1-2.22.3-2.5-1.8-1.7
Patch foraging water rate 18 sec0.30.40.70.9-0.6-0.70.6-0.7-0.3-0.3
Patch foraging water rate 24 sec0.10.10.2-0.10.40.4-0.30.10.40.3
Patch foraging water rate 6 sec0.30.41.11.0-0.6-0.60.6-0.7-0.4-0.4
Seeking ratio, delayed vs. immediate footshock1.82.13.31.0-1.3-1.31.3-1.4-1.8-1.8
Distance traveled before self-admin0.00.00.10.20.20.0-0.10.2-0.3-0.3
Distance traveled after self-admin2.02.34.92.2-1.4-1.41.4-1.1-1.3-1.4
Extensor digitorum longus weight8.131.834.14.8-5.8-5.85.7-5.7-5.8-5.8
Bone: elastic displacement0.00.00.10.0-0.2-0.20.2-0.2-0.3-0.2
Bone: elastic work0.00.10.1-0.10.30.3-0.30.30.10.1
Bone: endosteal estimation2.55.35.62.4-2.3-2.32.2-2.3-2.3-2.4
Bone: endosteal perimeter3.77.79.13.0-2.7-2.72.6-2.8-2.7-2.8
Epididymis fat weight0.00.10.3-0.5-0.2-0.10.0-0.00.40.6
Delta time in closed arm before/after self-admin0.00.00.20.5-0.10.0-0.0-0.00.10.1
Delta time in open arm before/after self-admin1.01.01.6-0.60.90.9-0.81.11.21.3
Diff in mean of infusions in LGA sessions0.80.91.4-0.1-1.0-1.00.9-0.9-1.2-1.0
Delay discount exponential model param0.00.00.10.20.10.1-0.10.10.3-0.0
Extinction: sum of active levers before priming0.90.91.2-0.41.01.1-0.90.91.11.0
Active lever presses in extinction session 60.10.10.2-0.10.10.1-0.10.1-0.3-0.5
Bone: final force0.71.22.61.6-1.0-1.00.9-0.9-1.0-1.0
Bone: final moment0.50.72.41.6-0.7-0.70.6-0.6-0.7-0.7
Food consumed during 24 hour testing period0.60.72.81.7-0.6-0.60.6-0.6-0.7-0.6
Glucose0.50.81.00.8-0.9-0.81.0-0.9-0.9-1.0
Heart weight0.40.61.00.7-1.0-1.00.8-0.9-0.4-0.3
Delay discount hyperbolic model param0.00.00.10.3-0.0-0.00.1-0.10.2-0.1
Intermittent access intake day 1-15 change0.00.00.10.3-0.0-0.10.2-0.2-0.00.1
Intermittent access intake escalation0.00.00.0-0.00.20.1-0.00.00.10.1
Intermittent access intake escalation 20.20.20.30.4-0.3-0.40.4-0.4-0.4-0.5
Intermitt. access day 1 inactive lever presses0.40.40.90.30.90.8-0.70.70.30.4
Intermitt. access day 15 inactive lever presses0.20.20.6-0.10.30.3-0.40.20.70.8
Intermitt. access escalation Index0.50.50.80.5-0.6-0.60.5-0.6-0.9-0.9
Intermittent access day 1 total infusions1.01.21.70.11.31.2-1.21.21.10.9
Intermittent access day 15 total infusions0.80.91.4-0.21.21.1-1.01.01.10.9
Intermittent access terminal intake (last 3 days)0.70.81.3-0.21.21.0-1.01.00.80.7
Intermittent access total infusions0.80.91.30.31.11.1-1.01.01.00.9
Intermittent access day 1 locomotion2.02.02.9-0.61.71.7-1.61.51.41.2
Intermittent access day 15 total locomotion1.51.62.30.11.51.4-1.41.41.21.2
Intermittent access total locomotion0.30.30.50.50.70.7-0.50.60.60.5
Intermittent access standard deviation0.60.60.9-0.11.00.9-0.80.80.70.7
Left kidney weight2.15.98.93.0-2.4-2.42.3-2.4-2.3-2.1
Right kidney weight1.33.64.31.6-2.1-2.11.9-2.0-1.8-1.7
Cocaine induced anxiety0.30.31.6-1.20.20.2-0.30.30.30.3
Post-drug Anxiety1.61.86.1-2.51.11.1-1.01.11.11.0
Baseline Anxiety0.60.60.9-1.00.80.8-0.70.70.70.9
Tail length0.10.20.6-0.80.50.4-0.30.30.20.3
Length with tail0.10.30.91.0-0.4-0.40.4-0.4-0.3-0.2
Length without tail0.92.06.42.5-1.4-1.41.1-1.2-0.8-0.7
Times rat made contact with spout0.20.20.60.00.40.3-0.50.40.70.7
Lifetime Intake0.91.01.40.11.21.1-1.01.11.10.9
Liver weight, left1.11.71.91.1-1.3-1.21.4-1.4-1.4-1.4
Liver weight, right2.74.55.71.2-2.1-2.12.2-2.2-2.4-2.3
Locomotor activity4.36.89.03.0-2.6-2.52.5-2.5-2.7-2.4
Locomotor testing distance2.64.36.82.6-2.1-2.02.1-2.0-2.0-1.9
Locomotor testing rearing1.01.51.71.2-1.3-1.11.3-1.2-1.2-1.2
Locomotion in novel chamber0.91.11.7-0.21.31.2-1.21.30.90.9
Locomotion in novel chamber post-restriction0.10.20.4-0.70.30.4-0.30.30.40.4
Fecal boli incidents, locomotor time 10.30.40.6-0.80.50.5-0.60.60.70.6
Change in fecal boli incidents, locomotor task1.51.44.02.0-0.8-0.70.9-0.9-1.3-1.1
Time >=10cm from walls, locomotor time 10.91.01.60.6-1.0-1.01.0-0.9-1.0-1.3
Bouts of movement, locomotor time 10.10.10.3-0.1-0.5-0.50.4-0.4-0.3-0.2
Total resting periods, locomotor time 10.00.00.1-0.1-0.3-0.30.2-0.1-0.00.0
Rest time, locomotor task time 10.40.40.6-0.30.70.7-0.70.80.50.7
Distance moved, locomotor task time 10.10.10.2-0.2-0.2-0.20.2-0.3-0.2-0.4
Vertical activity count, locomotor time 10.00.00.2-0.40.00.0-0.00.0-0.1-0.3
Time >=10cm from walls, locomotor time 20.00.00.10.1-0.2-0.20.1-0.00.0-0.1
Bouts of movement, locomotor time 21.21.31.60.4-1.3-1.21.2-1.3-1.1-1.2
Total resting periods, locomotor time 21.21.31.60.4-1.2-1.21.2-1.3-1.1-1.1
Rest time, locomotor task time 20.50.60.9-0.40.90.9-0.80.90.50.8
Distance moved, locomotor task time 20.20.30.60.0-0.4-0.40.5-0.6-0.6-0.8
Vertical activity count, locomotor time 20.50.50.7-0.60.80.9-0.70.80.60.5
Light reinforcement 12.13.95.11.1-2.3-2.32.0-2.0-1.8-2.0
Light reinforcement 21.11.41.9-0.01.41.3-1.41.31.21.1
Bone: marrow area2.65.66.22.5-2.3-2.32.3-2.4-2.3-2.4
Bone: maximum diameter2.34.38.93.0-1.9-1.81.8-1.9-1.9-1.9
Bone: maximum force0.81.52.51.6-1.2-1.21.1-1.1-1.1-1.1
Bone: maximum moment0.61.02.51.6-0.9-0.90.8-0.8-0.8-0.9
Mean time between licks in bursts1.11.52.1-0.81.41.3-1.31.41.21.2
Mean num. licks in bursts1.41.63.11.8-1.3-1.31.2-1.3-1.0-0.9
Cd content in liver0.10.10.6-0.8-0.0-0.0-0.0-0.0-0.1-0.1
Co content in liver0.10.21.0-1.00.10.1-0.20.20.20.2
Cu content in liver0.50.60.90.3-0.8-0.80.7-0.7-0.9-0.9
Fe content in liver0.30.40.9-1.00.50.5-0.50.50.60.6
K content in liver1.01.01.20.9-1.1-1.11.0-1.1-0.8-0.8
Mg content in liver3.03.13.31.4-1.8-1.81.7-1.8-1.8-1.8
Mn content in liver0.10.10.70.8-0.1-0.10.00.0-0.2-0.2
Na content in liver1.61.72.20.8-1.3-1.31.3-1.3-1.5-1.5
Rb content in liver2.73.33.71.6-1.9-1.91.9-1.9-1.8-1.7
Se content in liver0.40.50.8-0.10.70.7-0.70.70.90.9
Sr content in liver0.60.51.0-1.00.70.7-0.70.70.60.6
Zn content in liver0.30.30.4-0.50.60.6-0.60.60.50.5
Bone: minimum diameter0.10.10.91.0-0.1-0.1-0.1-0.0-0.0-0.1
Time in familiar zone, hab. session 10.10.10.4-0.6-0.1-0.1-0.00.00.30.2
Time in novel zone, hab. session 10.10.10.30.60.40.4-0.30.30.30.3
Total zone transitions, hab. session 10.10.10.8-0.90.00.0-0.10.00.40.3
Total locomotion distance, hab. session 10.10.10.3-0.6-0.4-0.40.3-0.4-0.0-0.0
Locomotion velocity, hab. session 10.10.20.4-0.3-0.6-0.60.5-0.6-0.2-0.2
Time in familiar zone, hab. session 20.00.00.1-0.20.20.2-0.10.20.30.2
Time in novel zone, hab. session 20.10.10.50.7-0.0-0.0-0.10.0-0.1-0.0
Total zone transitions, hab. session 20.40.51.0-1.0-0.7-0.70.5-0.7-0.4-0.5
Total locomotion distance, hab. session 20.50.70.9-0.8-1.0-1.00.8-0.9-0.6-0.7
Locomotion velocity, hab. session 20.30.50.6-0.8-0.8-0.80.6-0.8-0.5-0.5
Novel to familiar place preference ratio1.11.11.20.8-1.1-1.11.0-1.1-1.1-1.0
Novelty place preference1.21.21.50.9-1.2-1.21.1-1.1-1.1-1.1
Time in novel zone, NPP test1.41.41.61.2-1.3-1.31.1-1.2-1.2-1.1
Total zone transitions, NPP test0.30.40.6-0.6-0.8-0.80.7-0.8-0.4-0.5
Total locomotion distance, NPP test0.60.81.2-0.3-1.1-1.11.0-1.1-0.7-0.7
Locomotion velocity, NPP test0.30.50.6-0.8-0.8-0.80.7-0.8-0.4-0.4
Intraocular pressure0.00.00.10.10.0-0.0-0.00.00.30.2
Delta distance traveled before/after self-admin3.13.36.02.4-1.9-1.81.9-1.5-1.5-1.6
Delta ambulatory time before/after self-admin1.71.95.52.3-1.3-1.21.3-1.0-0.9-1.0
Parametrial fat weight0.40.71.0-0.71.00.9-0.80.70.91.0
Pavlov. Cond. lever latency0.30.32.11.40.30.2-0.10.20.10.2
Pavlov. Cond. magazine entry latency2.33.09.2-3.01.31.3-1.61.51.41.3
Pavlov. Cond. change in total contacts0.30.42.3-1.50.20.2-0.30.30.20.2
Pavlov. Cond. index score1.62.07.9-2.80.91.0-1.21.01.00.9
Pavlov. Cond. latency score1.11.56.6-2.60.70.7-0.90.80.80.7
Pavlov. Cond. lever contacts0.30.42.5-1.60.20.2-0.40.30.30.1
Pavlov. Cond. magazine entry number2.43.08.22.9-1.4-1.41.6-1.5-1.5-1.4
Pavlov. Cond. intertrial magazine entries0.40.50.70.0-0.6-0.60.8-0.8-0.8-0.8
Pavlov. Cond. lever-magazine prob. diff.1.41.77.3-2.70.80.8-1.10.90.90.7
Pavlov. Cond. response bias1.31.55.8-2.40.80.9-1.11.00.90.7
Pavlov. Cond. lever latency0.60.91.11.1-0.8-0.80.9-0.9-0.9-1.0
Pavlov. Cond. magazine entry latency4.45.15.7-1.82.32.3-2.42.42.32.3
Pavlov. Cond. change in total contacts0.81.21.3-1.11.11.1-1.11.11.01.1
Pavlov. Cond. index score1.62.12.4-1.31.41.4-1.51.41.51.5
Pavlov. Cond. latency score1.31.61.9-0.91.31.2-1.31.31.31.4
Pavlov. Cond. lever contacts0.40.60.9-0.90.70.7-0.80.70.70.7
Pavlov. Cond. magazine entry number3.44.14.51.6-2.1-2.02.1-2.1-2.1-2.1
Pavlov. Cond. intertrial magazine entries0.70.91.41.2-1.0-1.01.1-1.1-0.6-0.6
Pavlov. Cond. lever-magazine prob. diff.2.02.52.8-1.41.61.6-1.71.61.61.7
Pavlov. Cond. response bias1.62.13.1-1.81.41.4-1.51.41.41.4
Time in closed arm before self-admin0.20.20.7-0.80.40.4-0.40.20.30.4
Time in closed arm after self-admin0.00.00.00.1-0.2-0.10.1-0.2-0.10.1
Time in open arm before self-admin1.31.42.51.6-1.2-1.21.1-1.0-1.0-1.0
Time in open arm after self-admin0.10.10.40.70.20.2-0.10.30.30.2
Bone: periosteal estimation1.93.96.82.6-1.8-1.81.8-1.9-1.9-1.9
Bone: periosteal perimeter2.64.36.42.5-1.9-1.91.9-2.0-2.1-2.1
Bone: post-yield work0.40.50.70.2-0.8-0.80.8-0.7-0.7-0.7
Progressive ratio test 1 active lever presses0.10.10.60.8-0.1-0.00.2-0.2-0.0-0.2
Progressive ratio test 1 breakpoint0.10.10.20.40.40.4-0.20.30.30.1
Progressive ratio test 1 inactive lever presses0.80.81.40.31.21.1-0.90.91.10.6
Progressive ratio test 2 active lever presses0.40.41.41.2-0.4-0.50.5-0.6-0.4-0.6
Progressive ratio test 2 breakpoint0.50.62.31.5-0.5-0.60.6-0.7-0.4-0.6
Progressive ratio test 2 inactive lever presses0.91.01.60.41.11.0-1.11.01.31.1
Incentive Sensitization - Responses1.31.32.41.6-1.0-1.21.1-1.1-1.1-1.0
Incentive Sensitization - Breakpoint1.11.11.81.4-0.9-1.11.0-1.0-1.0-0.9
Sum of active levers in priming session hrs 5-60.20.20.40.6-0.5-0.40.4-0.3-0.3-0.5
Progressive ratio0.50.51.9-1.40.60.4-0.70.70.50.3
Food seeking constrained by brief footshock0.81.01.50.7-0.9-1.11.0-1.2-1.2-1.0
Seeking ratio, punishment vs. effort3.34.05.52.3-1.9-1.82.1-2.2-2.0-1.8
Retroperitoneal fat weight0.10.20.4-0.1-0.6-0.50.3-0.40.50.6
Reaction time number correct2.33.33.81.7-1.9-1.91.9-1.9-1.7-1.8
Reaction time mean minus median0.50.60.8-0.60.80.8-0.80.80.90.7
Reaction time mean minus median AUC1.21.52.4-0.91.21.2-1.21.21.51.4
Reaction time num false alarms0.10.20.3-0.40.30.4-0.30.30.60.6
Reaction time num false alarms AUC0.00.00.10.2-0.2-0.20.3-0.30.20.2
Reaction time trials correct on left2.33.33.81.7-1.9-1.91.9-1.9-1.7-1.8
Reaction time trials on left2.33.33.81.7-1.9-1.91.9-1.9-1.6-1.8
Reaction time mean3.65.05.9-1.72.42.4-2.42.42.32.2
Reaction time mean AUC3.64.85.6-1.82.32.3-2.32.42.12.0
Median of all reaction times4.46.17.0-1.82.62.6-2.62.72.52.4
Reaction time omissions0.00.00.0-0.0-0.00.00.0-0.00.0-0.2
Reaction time false alarm rate0.81.11.6-0.91.01.0-1.01.01.21.3
Reaction time premature initiation rate1.01.31.50.8-1.2-1.21.2-1.2-1.1-1.1
Reaction time premature initiations2.73.84.31.6-2.1-2.12.1-2.1-1.8-1.9
Std. dev. reaction times1.92.73.0-1.31.71.7-1.71.71.71.5
Reaction time trials completed2.33.33.81.7-1.9-1.91.9-1.9-1.6-1.8
Reaction time trials AUC2.02.93.41.6-1.8-1.81.8-1.8-1.5-1.6
Run reversals in cocaine runway, females0.20.10.50.7-0.3-0.40.3-0.20.30.3
Run reversals in cocaine runway, males0.50.50.9-0.2-0.8-0.80.8-0.9-0.7-0.6
Latency to leave start box in cocaine runway2.02.13.71.2-1.4-1.21.4-1.2-1.8-1.9
Latency to leave start box in cocaine runway, F0.70.71.40.4-0.8-0.60.9-0.7-1.1-1.2
Latency to leave start box in cocaine runway, M2.22.12.71.4-1.4-1.41.3-1.4-1.5-1.6
Std. dev. time between licks in bursts0.10.10.30.2-0.2-0.40.4-0.2-0.5-0.5
Total sessions with >9 infusions0.20.20.70.8-0.1-0.00.3-0.1-0.5-0.4
Short access day 1 total inactive lever presses0.91.04.42.1-0.4-0.50.7-0.5-0.7-1.0
Short access day 10 total inactive lever presses0.60.71.00.20.90.8-0.80.80.91.0
Short access day 1 total infusions0.20.20.50.30.60.7-0.50.70.0-0.0
Short access day 10 total infusions1.01.12.0-0.11.11.1-1.11.21.40.9
Short access total infusions1.21.31.8-0.21.41.3-1.21.31.21.0
Short access day 1 locomotion0.10.10.30.4-0.10.00.2-0.1-0.6-0.5
Short access day 10 total locomotion0.10.10.70.90.30.3-0.20.20.10.1
Short access total locomotion1.11.21.8-0.11.31.3-1.11.20.91.0
One hour access (0.3 mA shock)0.10.10.50.70.1-0.0-0.00.0-0.2-0.1
Compulsive drug intake0.50.51.10.8-0.5-0.50.6-0.4-1.1-0.8
One hour access (shock baseline)0.70.81.3-0.30.90.8-0.90.81.21.0
Social response proportion0.20.20.50.7-0.3-0.30.2-0.4-0.5-0.4
Social responses0.10.10.30.2-0.4-0.40.3-0.6-0.20.0
Social time0.20.20.60.8-0.5-0.50.4-0.6-0.1-0.0
Soleus weight16.949.454.35.8-7.1-7.27.1-7.1-7.4-7.3
Bone: stiffness1.72.73.81.9-1.6-1.61.6-1.6-1.5-1.6
Tibialis anterior weight13.546.247.86.9-6.7-6.86.8-6.7-6.8-6.8
Time to tail flick, vehicle, before self-admin0.40.53.0-1.70.30.2-0.2-0.2-0.0-0.1
Time to tail flick, vehicle, after self-admin0.30.31.31.1-0.2-0.20.2-0.3-0.4-0.7
Time to tail flick, test, before self-admin0.70.72.0-1.40.60.7-0.70.70.70.8
Time to tail flick, test, after self-admin1.11.21.6-0.81.21.3-1.11.20.91.1
Delta time to tail flick, vehicle, before/after SA0.40.42.11.50.30.3-0.30.40.2-0.0
Delta time to tail flick, test, before/after SA0.20.20.91.00.40.4-0.20.20.10.2
Tibia length0.10.20.40.60.40.4-0.60.60.50.4
Ambulatory time before self-admin0.30.30.6-0.40.60.6-0.60.70.40.4
Ambulatory time after self-admin1.31.45.02.2-1.0-1.01.0-0.6-0.8-1.0
Bone: tissue strength1.51.41.8-0.71.21.2-1.21.21.31.3
Total heroin consumption1.61.92.60.7-1.5-1.51.6-1.4-1.3-1.4
Bone: trabecular number0.60.91.2-0.90.90.9-0.90.91.11.0
Bone: trabecular spacing0.00.10.2-0.50.20.2-0.20.2-0.0-0.0
Bone: trabecular thickness0.20.21.51.2-0.1-0.10.1-0.00.10.1
Bone: trabecular tissue density6.99.719.74.4-2.9-2.92.9-2.7-2.9-2.7
Water consumed over 24 hours0.40.50.6-0.30.70.7-0.80.70.60.7
Number of responses in last shaping day0.00.00.10.30.00.20.10.1-0.0-0.2