Hub : Genes

Vps51

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver mRNA stability Vps51 0.09 0.04 7.6e-09 0.04 0.04 0.04 0.04 3.1e-05 9.1e-06 8.0e-05 3.6e-05
2 Liver intron excision ratio chr1_212793428_212798857 0.18 0.08 2.7e-15 0.1 0.09 0.09 0.09 2.0e-11 1.1e-09 7.3e-10 6.5e-10
3 Liver intron excision ratio chr1_212794727_212798857 0.13 0.06 3.7e-13 0.09 0.07 0.07 0.07 3.4e-10 2.2e-08 3.4e-08 2.2e-08
4 pVTA mRNA stability Vps51 0.03 0.02 3.5e-03 0.02 0.01 0.01 0.01 5.2e-03 4.8e-02 6.2e-02 8.2e-02
5 Liver gene expression Vps51 0.1 0.05 2.5e-10 0.06 0.08 0.07 0.08 2.7e-07 2.7e-09 2.9e-08 5.5e-09
6 Eye mRNA stability Vps51 0.31 0.15 6.0e-03 0.02 0 -0.02 0.01 1.4e-01 3.1e-01 6.5e-01 2.4e-01
7 pVTA gene expression Vps51 0.12 0.06 2.0e-07 0.1 0.09 0.08 0.09 2.2e-08 2.2e-07 2.6e-07 1.7e-07
8 RMTg mRNA stability Vps51 0.17 0.1 3.3e-03 0.02 0 -0.01 0.01 9.5e-02 3.0e-01 6.6e-01 1.5e-01
9 NAcc gene expression Vps51 0.16 0.07 0.0e+00 0.12 0.13 0.13 0.13 3.3e-17 5.5e-19 1.7e-18 5.2e-19
10 IC gene expression Vps51 0.34 0.13 7.7e-11 0.12 0.26 0.25 0.24 6.7e-06 2.1e-11 5.7e-11 1.1e-10
11 Brain gene expression Vps51 0.45 0.13 0.0e+00 0.25 0.29 0.28 0.29 1.2e-23 5.7e-27 1.1e-26 2.3e-27
12 BLA gene expression Vps51 0.51 0.15 6.6e-12 0.18 0.19 0.19 0.2 1.2e-09 3.0e-10 1.6e-10 8.4e-11
13 PL gene expression Vps51 0.47 0.13 0.0e+00 0.2 0.24 0.24 0.24 2.1e-21 8.4e-26 1.6e-26 7.7e-26
14 Adipose gene expression Vps51 0.11 0.05 9.6e-09 0.05 0.06 0.06 0.06 5.1e-06 9.3e-08 1.0e-07 2.9e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bone: apparent density0.91.73.70.80.9-0.9-0.9-1.5-0.70.80.6-1.9-1.6-1.5-1.91.8-1.4
Area under the delay curve0.20.31.0-0.2-0.30.3-0.0-0.0-0.30.81.0-0.6-0.5-0.2-0.20.5-0.9
BMI with tail3.110.723.52.22.6-2.6-2.3-3.6-2.01.51.5-4.7-3.6-3.9-4.84.4-3.5
BMI without tail0.52.76.21.31.4-1.4-1.5-1.7-1.60.61.0-2.5-1.5-1.7-2.21.9-1.9
Body weight1.98.114.43.63.7-3.7-3.7-3.8-3.6-1.2-1.1-2.8-1.3-1.8-3.42.2-1.0
Weight adjusted by age0.41.22.51.61.4-1.4-1.4-1.4-1.5-1.4-1.3-0.10.30.4-0.2-0.50.9
Bone surface3.16.115.13.23.2-3.2-3.0-3.9-2.2-0.5-1.3-2.6-1.8-1.3-2.81.9-0.5
Bone volume1.73.38.11.91.8-1.8-1.7-2.8-1.00.4-0.3-2.5-2.1-1.6-2.52.0-1.1
Breakpoint value in progressive ratio session1.22.24.92.22.2-2.2-2.0-2.2-1.6-0.9-1.3-1.2-0.30.3-0.60.00.4
Number of licking bursts0.10.20.60.70.6-0.6-0.6-0.8-0.4-0.2-0.4-0.5-0.20.0-0.20.00.1
Context. condit. distance diff. score1.11.43.0-1.7-1.71.71.61.51.11.11.40.3-0.2-0.50.20.3-0.8
Locomotion velocity, session 10.20.20.7-0.0-0.10.1-0.10.5-0.6-0.7-0.20.80.80.30.2-0.40.4
Locomotion distance, session 10.60.81.60.60.7-0.7-0.7-0.7-1.00.20.6-1.2-0.7-1.0-1.31.1-1.1
Locomotion velocity, session 21.61.93.71.81.8-1.8-1.8-1.8-1.9-0.6-0.6-1.4-0.5-0.6-1.30.9-0.4
Locomotion distance, session 20.50.71.40.80.9-0.9-0.9-0.8-1.2-0.10.3-1.2-0.4-0.7-0.80.7-0.8
Locomotion velocity, session 31.11.23.0-0.6-0.30.30.60.20.30.91.3-0.9-1.1-1.7-1.71.7-1.6
Locomotion distance, session 30.00.00.1-0.2-0.00.00.30.20.00.10.3-0.1-0.0-0.2-0.30.1-0.2
Stereotopy head waving bouts, day 31.31.53.7-1.0-0.90.91.00.60.51.01.5-0.5-1.0-1.9-1.71.8-1.7
Stereotopy head waving duration, day 30.81.01.7-1.0-1.01.00.90.50.81.01.2-0.4-0.9-1.3-1.01.2-1.2
Locomotion velocity, session 71.71.94.1-0.7-0.70.70.7-0.10.71.71.8-1.6-1.7-1.8-1.61.8-2.0
Locomotion distance, session 70.30.41.1-0.3-0.00.00.30.3-0.20.60.9-0.6-0.4-0.8-0.70.8-1.1
Stereotopy head waving bouts, day 70.50.61.7-0.0-0.20.20.0-0.70.50.90.5-1.1-1.3-1.0-1.00.9-0.8
Stereotopy head waving duration, day 70.70.92.61.00.8-0.8-1.0-1.6-0.50.4-0.0-1.4-1.2-0.6-0.90.7-0.6
Locomotion velocity, session 80.81.02.61.01.1-1.1-1.0-0.2-1.6-1.5-1.10.61.10.40.1-0.40.8
Locomotion distance, session 80.71.02.4-0.7-0.60.60.60.20.41.01.1-0.9-1.0-1.6-1.31.5-1.4
Degree of sensitization distance0.50.61.7-0.10.0-0.00.1-0.1-0.10.60.6-0.7-0.7-1.2-1.21.3-1.1
Degree of sensitization stereotypy0.50.62.10.80.7-0.7-0.8-1.4-0.10.4-0.2-1.3-1.1-0.4-0.70.6-0.4
Conditioned locomotion0.81.02.11.41.5-1.5-1.3-1.1-1.3-1.1-1.1-0.20.30.1-0.50.00.5
Cocaine response after cond. corrected0.71.12.8-1.5-1.41.41.51.70.90.51.20.80.3-0.40.00.3-0.6
Cocaine response after cond. not corrected0.50.81.9-1.3-1.21.21.21.40.70.41.00.60.1-0.5-0.20.4-0.6
Cocaine response before conditioning0.50.61.61.11.1-1.1-1.2-1.3-0.6-0.3-0.8-0.7-0.30.2-0.3-0.10.3
Saline control response2.33.27.12.42.5-2.5-2.6-1.8-2.7-2.0-1.8-0.20.70.4-0.5-0.20.9
Bone: connectivity density1.82.96.12.02.2-2.2-2.0-2.5-1.7-0.0-0.2-2.0-1.3-1.1-2.01.6-0.9
Bone: cortical apparent density0.40.62.00.30.4-0.4-0.20.1-0.2-0.5-0.40.50.81.41.4-1.40.9
Bone: cortical area0.50.81.71.21.1-1.1-1.2-1.3-0.8-0.6-0.9-0.6-0.3-0.2-0.80.50.3
Bone: cortical porosity0.10.10.40.40.3-0.3-0.4-0.6-0.30.20.1-0.6-0.4-0.2-0.30.3-0.3
Bone: cortical porosity0.30.40.80.80.7-0.7-0.8-0.9-0.8-0.1-0.2-0.7-0.3-0.2-0.50.4-0.2
Bone: cortical thickness2.44.06.22.22.2-2.2-2.4-1.1-2.4-2.5-2.30.81.82.01.1-1.72.0
Bone: cortical thickness1.11.32.90.60.8-0.8-0.70.4-1.2-1.4-1.01.11.71.51.2-1.41.2
Bone: cortical tissue density0.50.82.20.50.5-0.5-0.4-0.0-0.4-0.6-0.60.51.01.51.5-1.51.0
Condit. Reinf. active minus inactive responses0.10.10.40.30.3-0.3-0.4-0.4-0.50.10.2-0.6-0.20.0-0.00.1-0.3
Condit. Reinf. active-inactive response ratio0.10.10.60.1-0.10.1-0.2-0.0-0.2-0.00.1-0.10.20.80.8-0.60.2
Condit. Reinf. active responses0.30.41.00.00.1-0.10.0-0.40.00.60.5-1.0-0.8-0.7-0.70.8-0.8
Condit. Reinf. inactive responses0.91.23.1-0.3-0.20.20.4-0.40.61.10.8-1.1-1.4-1.8-1.71.7-1.3
Incentive salience index mean0.40.51.50.50.5-0.5-0.5-0.8-0.60.40.5-1.2-0.8-0.7-0.90.9-0.9
Condit. Reinf. lever presses0.71.02.50.80.8-0.8-0.7-1.3-0.40.3-0.0-1.4-1.2-1.2-1.61.4-0.9
Condit. Reinf. active minus inactive responses0.10.20.6-0.1-0.10.10.3-0.40.70.60.1-0.6-0.8-0.5-0.50.4-0.3
Condit. Reinf. active-inactive response ratio0.91.42.9-0.7-0.80.80.9-0.31.51.40.7-0.9-1.7-1.7-1.51.5-1.1
Condit. Reinf. active responses0.10.20.90.40.5-0.5-0.3-0.80.00.40.0-1.0-0.6-0.1-0.20.1-0.2
Condit. Reinf. inactive responses0.30.51.20.80.9-0.9-0.9-0.5-1.1-0.4-0.1-0.50.40.80.7-0.60.2
Condit. Reinf. lever presses1.21.85.11.81.8-1.8-1.6-2.3-0.9-0.5-1.2-1.5-0.9-0.3-1.20.60.1
Condit. Reinf. lever reinforcers received0.20.31.10.80.8-0.8-0.7-1.0-0.20.0-0.3-0.9-0.40.1-0.1-0.10.1
Conditioned reinforcement - actives0.10.20.80.3-0.10.1-0.1-0.90.6-0.2-0.90.0-0.7-0.4-0.50.10.5
Conditioned reinforcement - inactives0.71.96.5-1.8-1.91.92.01.02.61.50.90.6-0.9-0.50.30.1-0.2
Conditioned locomotion3.55.212.6-3.2-3.33.33.32.63.61.91.61.4-0.4-0.31.2-0.3-0.3
Patch foraging indifference point 0 sec0.00.00.1-0.20.1-0.1-0.00.00.10.30.3-0.3-0.2-0.1-0.00.2-0.3
Patch foraging indifference point AUC0.82.04.22.11.8-1.8-1.9-2.0-1.3-1.3-1.8-0.40.10.90.2-0.61.1
Delay disc. indifference point, 0s delay0.70.82.0-0.6-1.01.00.30.3-0.11.21.4-0.6-0.8-0.8-0.51.1-1.4
Delay disc. indifference point, 16s delay0.50.72.0-0.9-0.80.80.90.31.01.31.4-0.8-0.8-0.4-0.00.5-0.9
Delay disc. indifference point, 2s delay0.30.40.9-0.3-0.50.50.2-0.10.20.80.7-0.4-0.8-0.7-0.60.9-0.8
Delay disc. indifference point, 24s delay0.10.20.6-0.2-0.30.30.10.7-0.2-0.30.10.60.80.70.6-0.50.3
Delay disc. indifference point, 4s delay0.20.21.0-0.4-0.50.50.20.4-0.40.71.0-0.1-0.1-0.2-0.00.4-0.8
Delay disc. indifference point, 8s delay0.10.10.4-0.2-0.30.3-0.00.3-0.50.30.70.10.1-0.0-0.00.1-0.5
Indifference point function ln k2.26.715.1-3.9-3.53.53.63.92.82.02.91.40.2-1.00.50.6-1.5
Indifference point function log k2.26.715.1-3.9-3.53.53.63.92.82.02.91.40.2-1.00.50.6-1.5
Patch foraging total patch changes 0 sec0.00.10.2-0.10.2-0.2-0.10.3-0.2-0.2-0.10.30.40.30.4-0.30.2
Patch foraging total patch changes 12 sec2.43.37.32.62.6-2.6-2.7-2.4-2.4-1.3-1.6-1.30.00.7-0.3-0.30.6
Patch foraging total patch changes 18 sec0.20.51.61.00.9-0.9-1.1-1.3-0.8-0.1-0.4-0.8-0.6-0.2-0.50.4-0.1
Patch foraging total patch changes 24 sec0.62.13.81.81.8-1.8-1.9-1.3-1.7-1.8-1.90.20.91.00.3-0.81.3
Patch foraging total patch changes 6 sec0.50.82.21.21.5-1.5-1.3-0.9-1.3-0.7-0.6-0.40.20.2-0.20.10.1
Patch foraging time to switch 0 sec0.93.68.41.71.7-1.7-1.7-2.6-1.20.90.4-2.9-2.2-1.8-2.52.0-1.6
Patch foraging water rate 0 sec1.34.811.0-2.7-2.72.72.73.32.4-0.10.23.01.71.22.3-1.51.1
Patch foraging water rate 12 sec2.39.324.1-4.0-3.93.93.84.92.70.21.34.02.31.32.9-1.80.9
Patch foraging water rate 18 sec1.22.78.1-2.3-2.22.22.22.81.50.31.02.11.10.11.0-0.40.0
Patch foraging water rate 24 sec2.73.99.7-2.6-2.72.72.63.12.10.20.92.61.20.41.5-0.70.5
Patch foraging water rate 6 sec3.34.914.1-2.8-2.72.72.83.81.9-0.20.73.32.00.91.9-1.10.7
Seeking ratio, delayed vs. immediate footshock0.30.41.3-0.5-0.20.20.50.20.41.21.1-0.8-0.6-0.5-0.20.1-0.9
Distance traveled before self-admin0.40.92.71.10.9-0.9-1.0-1.7-0.40.3-0.2-1.4-1.1-0.6-1.00.8-0.4
Distance traveled after self-admin0.20.30.50.60.6-0.6-0.6-0.7-0.3-0.2-0.4-0.30.10.70.6-0.60.4
Extensor digitorum longus weight4.116.234.25.85.8-5.8-5.8-5.3-5.4-3.2-3.3-2.5-0.00.0-2.30.50.9
Bone: elastic displacement1.51.85.2-1.2-1.11.11.02.10.5-0.9-0.32.31.91.21.6-1.31.1
Bone: elastic work1.01.32.80.91.1-1.1-1.10.1-1.6-1.7-1.21.01.61.00.6-0.91.1
Bone: endosteal estimation1.84.410.4-1.2-1.11.11.1-0.11.32.22.0-1.7-2.5-3.2-2.93.2-2.6
Bone: endosteal perimeter2.15.211.4-1.3-1.41.41.4-0.31.92.52.0-1.9-3.0-3.4-3.13.3-2.7
Epididymis fat weight1.36.815.0-3.3-3.63.63.52.03.92.62.20.3-1.7-2.2-1.01.8-1.6
Delta time in closed arm before/after self-admin0.40.31.30.10.3-0.3-0.40.7-1.2-0.9-0.10.61.10.30.3-0.10.2
Delta time in open arm before/after self-admin0.20.31.40.70.5-0.5-0.5-1.20.20.0-0.7-0.5-0.50.3-0.0-0.20.5
Diff in mean of infusions in LGA sessions0.30.50.80.90.9-0.9-0.8-0.6-0.8-0.9-0.8-0.00.50.40.1-0.50.6
Delay discount exponential model param0.10.20.60.10.2-0.20.10.00.4-0.7-0.80.50.30.10.1-0.30.7
Extinction: sum of active levers before priming1.21.84.21.81.8-1.8-1.7-2.0-1.5-0.2-0.4-1.7-0.8-0.4-0.90.6-0.4
Active lever presses in extinction session 62.12.15.42.21.8-1.8-2.0-2.3-1.4-1.3-1.7-0.8-0.4-0.2-1.00.50.6
Bone: final force1.62.55.12.22.3-2.3-2.1-2.3-1.8-1.0-1.3-1.2-0.5-0.5-1.50.90.1
Bone: final moment1.42.34.72.12.2-2.2-2.1-2.1-1.7-1.0-1.2-1.1-0.5-0.5-1.50.90.1
Food consumed during 24 hour testing period0.20.41.20.30.1-0.1-0.2-0.20.2-0.6-1.00.50.50.90.8-1.01.1
Glucose2.74.38.2-2.2-2.12.12.11.21.82.42.9-1.0-1.8-2.3-1.62.2-2.5
Heart weight2.03.37.2-1.5-1.51.51.20.90.51.92.7-1.1-1.5-2.5-1.92.5-2.7
Delay discount hyperbolic model param0.20.20.70.10.2-0.20.10.10.3-0.7-0.80.50.40.20.3-0.50.8
Intermittent access intake day 1-15 change0.20.83.1-1.2-1.31.31.40.71.80.70.20.7-0.3-0.10.4-0.20.2
Intermittent access intake escalation0.10.72.9-1.0-1.11.11.20.51.70.5-0.10.7-0.3-0.10.4-0.30.4
Intermittent access intake escalation 20.40.62.5-0.9-1.01.01.10.51.60.5-0.10.6-0.30.00.5-0.30.4
Intermitt. access day 1 inactive lever presses0.00.20.4-0.4-0.40.40.40.30.40.30.30.30.10.60.6-0.60.2
Intermitt. access day 15 inactive lever presses0.31.64.1-1.5-1.61.61.60.62.01.71.2-0.2-1.3-1.0-0.40.7-0.9
Intermitt. access escalation Index0.82.55.0-2.2-2.22.22.01.91.81.82.00.2-0.4-0.40.50.5-1.1
Intermittent access day 1 total infusions1.95.69.5-1.9-2.02.01.90.32.23.02.7-1.6-2.8-3.1-2.22.9-2.8
Intermittent access day 15 total infusions2.05.011.8-2.6-2.92.92.81.23.42.61.9-0.0-2.1-2.1-0.91.6-1.5
Intermittent access terminal intake (last 3 days)3.05.210.4-2.4-2.62.62.50.73.22.82.0-0.6-2.6-2.7-1.62.3-1.9
Intermittent access total infusions4.25.08.0-2.1-2.32.32.20.62.72.72.2-0.9-2.6-2.8-1.92.5-2.2
Intermittent access day 1 locomotion1.83.35.7-1.7-1.81.81.70.51.92.42.2-1.0-2.1-2.2-1.42.0-2.1
Intermittent access day 15 total locomotion1.14.310.3-2.2-2.42.42.50.63.22.71.9-0.5-2.3-2.0-1.01.6-1.5
Intermittent access total locomotion6.57.713.8-2.8-3.03.02.90.73.73.72.9-1.1-3.3-3.0-1.82.7-2.6
Intermittent access standard deviation0.21.02.7-1.3-1.51.51.41.01.60.60.30.8-0.2-0.20.5-0.10.1
Left kidney weight0.32.53.9-1.7-2.02.01.40.71.52.01.8-0.9-1.6-1.6-1.01.6-1.7
Right kidney weight0.10.81.9-1.1-1.41.41.10.71.20.70.60.2-0.5-0.7-0.30.6-0.5
Cocaine induced anxiety0.00.10.30.30.2-0.2-0.2-0.60.00.1-0.1-0.2-0.4-0.1-0.2-0.00.0
Post-drug Anxiety0.40.51.11.01.0-1.0-0.9-1.0-0.7-0.5-0.7-0.4-0.2-0.1-0.60.10.3
Baseline Anxiety0.30.41.00.50.7-0.7-0.60.1-0.9-1.0-0.80.30.90.60.2-0.50.6
Tail length0.52.55.01.31.0-1.0-1.4-0.2-1.8-2.2-1.81.22.01.81.5-1.91.8
Length with tail1.35.611.43.02.9-2.9-3.0-1.8-3.4-3.1-2.80.41.71.30.1-1.31.9
Length without tail0.94.79.62.62.8-2.8-2.7-1.4-3.1-3.0-2.60.61.81.2-0.0-1.01.8
Times rat made contact with spout0.30.41.10.70.6-0.6-0.8-0.3-1.0-0.4-0.2-0.30.50.80.6-0.70.3
Lifetime Intake3.13.96.5-1.9-2.02.01.90.62.22.42.0-0.8-2.2-2.6-1.72.3-2.1
Liver weight, left0.50.82.0-1.3-1.31.31.21.40.80.30.71.00.2-0.6-0.10.5-0.3
Liver weight, right1.32.26.0-2.3-2.12.12.02.51.20.71.41.40.4-0.9-0.10.6-0.8
Locomotor activity1.72.67.7-2.1-1.81.81.92.81.2-0.20.52.41.60.81.5-0.90.6
Locomotor testing distance1.43.610.7-2.3-2.22.22.13.31.3-0.40.62.91.90.91.8-1.10.7
Locomotor testing rearing0.82.98.4-2.2-2.22.21.92.91.20.00.92.31.50.91.7-0.90.4
Locomotion in novel chamber2.83.88.5-2.7-2.72.72.81.92.92.01.60.6-1.0-1.4-0.20.9-1.0
Locomotion in novel chamber post-restriction0.82.45.8-2.1-2.22.22.11.42.41.91.40.3-0.8-0.60.30.6-0.8
Fecal boli incidents, locomotor time 10.10.31.00.30.0-0.0-0.3-1.00.50.6-0.3-0.6-1.0-0.5-0.50.3-0.1
Change in fecal boli incidents, locomotor task0.10.20.4-0.30.1-0.10.30.6-0.4-0.20.6-0.00.2-0.4-0.30.6-0.6
Time >=10cm from walls, locomotor time 12.73.37.2-0.7-0.80.80.7-0.81.32.31.5-1.9-2.7-2.7-2.32.6-2.1
Bouts of movement, locomotor time 11.62.14.81.61.4-1.4-1.4-1.2-0.8-1.2-1.40.10.92.21.7-2.11.5
Total resting periods, locomotor time 11.11.32.81.31.2-1.2-1.1-1.1-0.5-0.7-1.1-0.10.41.71.4-1.61.2
Rest time, locomotor task time 10.60.92.6-1.3-1.41.41.31.11.60.60.40.8-0.1-0.20.50.0-0.0
Distance moved, locomotor task time 10.20.61.80.30.4-0.4-0.3-0.6-0.50.60.6-0.9-0.8-0.9-1.31.0-1.0
Vertical activity count, locomotor time 10.10.61.4-1.2-1.01.01.11.10.90.71.00.3-0.1-0.4-0.20.2-0.5
Time >=10cm from walls, locomotor time 20.10.20.90.50.1-0.1-0.2-0.90.20.4-0.2-0.6-0.8-0.2-0.20.2-0.0
Bouts of movement, locomotor time 20.10.41.10.80.9-0.9-0.6-0.7-0.5-0.2-0.4-0.40.21.10.7-0.80.5
Total resting periods, locomotor time 20.00.20.60.50.6-0.6-0.3-0.6-0.10.2-0.0-0.5-0.10.70.6-0.50.1
Rest time, locomotor task time 21.11.83.4-1.8-1.81.81.81.31.71.41.50.3-0.7-0.8-0.10.8-1.0
Distance moved, locomotor task time 20.81.01.71.31.2-1.2-1.3-0.9-1.3-1.2-1.20.30.70.90.2-0.81.0
Vertical activity count, locomotor time 20.51.22.9-0.1-0.00.00.01.0-0.4-1.4-0.91.71.71.21.1-1.41.4
Light reinforcement 10.10.30.9-0.3-0.40.40.00.50.1-0.2-0.10.80.60.81.0-0.80.6
Light reinforcement 20.30.62.1-0.8-1.11.10.80.11.40.90.30.3-0.9-0.8-0.40.5-0.2
Bone: marrow area1.94.610.8-1.3-1.11.11.2-0.01.32.32.1-1.8-2.6-3.3-3.03.3-2.8
Bone: maximum diameter0.40.72.30.70.6-0.6-0.6-1.30.0-0.1-0.7-0.8-1.0-1.1-1.51.2-0.2
Bone: maximum force2.44.710.42.62.6-2.6-2.5-3.2-1.8-0.3-0.8-2.5-1.7-1.6-2.82.0-0.8
Bone: maximum moment2.34.39.32.42.5-2.5-2.4-3.1-1.8-0.3-0.7-2.4-1.6-1.6-2.72.0-0.8
Mean time between licks in bursts0.10.61.70.40.6-0.6-0.50.5-1.3-1.1-0.50.91.30.60.6-0.70.6
Mean num. licks in bursts0.10.20.7-0.6-0.50.50.50.80.10.10.50.40.50.50.8-0.50.0
Cd content in liver0.70.82.9-1.0-1.11.11.20.31.71.30.6-0.2-0.9-0.3-0.00.2-0.4
Co content in liver2.42.97.3-1.3-1.31.31.22.30.5-0.6-0.12.32.12.12.7-2.21.3
Cu content in liver0.20.20.6-0.1-0.10.10.1-0.10.10.80.8-0.8-0.50.10.30.0-0.5
Fe content in liver0.20.20.80.40.4-0.4-0.4-0.2-0.3-0.9-0.70.50.3-0.3-0.50.20.4
K content in liver0.50.51.40.60.7-0.7-0.6-0.6-0.90.10.2-0.8-0.5-0.8-1.21.0-0.8
Mg content in liver0.30.41.0-0.7-0.60.60.60.70.20.71.0-0.2-0.2-0.5-0.30.6-0.9
Mn content in liver2.02.24.82.22.1-2.1-2.0-2.2-1.4-1.2-1.6-0.9-0.2-0.0-0.90.20.6
Na content in liver0.50.51.50.70.7-0.7-0.8-0.4-0.8-1.1-1.20.60.70.50.1-0.40.9
Rb content in liver1.21.43.3-1.8-1.61.61.71.81.21.01.50.40.1-0.10.40.1-0.7
Se content in liver0.20.20.9-0.3-0.40.40.4-0.31.00.50.1-0.3-0.7-0.5-0.40.4-0.2
Sr content in liver2.21.93.31.81.6-1.6-1.7-1.3-1.5-1.5-1.80.30.81.20.5-1.01.5
Zn content in liver0.20.20.60.60.5-0.5-0.8-0.5-0.8-0.1-0.0-0.30.10.40.4-0.30.0
Bone: minimum diameter2.14.07.7-1.1-1.01.01.0-0.21.22.52.3-2.1-2.5-2.6-2.32.8-2.7
Time in familiar zone, hab. session 10.40.40.9-0.6-0.50.50.50.20.60.90.8-0.5-0.7-0.9-0.50.7-0.9
Time in novel zone, hab. session 10.60.72.0-0.4-0.40.40.41.1-0.1-0.8-0.31.41.30.90.9-0.90.8
Total zone transitions, hab. session 10.30.51.11.01.0-1.0-0.9-1.0-0.8-0.1-0.2-1.1-0.30.2-0.2-0.1-0.1
Total locomotion distance, hab. session 10.60.81.6-0.6-0.60.60.70.10.71.11.2-1.0-1.1-1.2-1.01.1-1.2
Locomotion velocity, hab. session 10.30.41.1-0.1-0.10.10.2-0.30.20.70.8-1.0-0.9-0.8-0.80.9-0.9
Time in familiar zone, hab. session 20.40.41.5-0.20.0-0.0-0.10.9-0.5-0.8-0.31.21.20.50.6-0.40.5
Time in novel zone, hab. session 20.20.21.20.30.2-0.2-0.1-0.70.00.60.4-1.1-0.8-0.2-0.30.2-0.5
Total zone transitions, hab. session 21.52.04.91.21.3-1.3-1.3-1.7-1.50.40.7-2.2-1.3-1.3-1.71.4-1.4
Total locomotion distance, hab. session 21.11.53.4-0.2-0.10.10.1-0.4-0.31.11.5-1.7-1.4-1.7-1.61.8-1.8
Locomotion velocity, hab. session 21.41.94.1-0.3-0.30.30.3-0.40.11.31.7-1.8-1.7-2.0-1.92.0-2.0
Novel to familiar place preference ratio0.70.93.61.31.1-1.1-1.0-1.9-0.40.1-0.7-1.4-1.0-0.2-0.70.3-0.0
Novelty place preference0.40.52.20.90.7-0.7-0.6-1.5-0.10.3-0.3-1.2-1.0-0.1-0.50.2-0.1
Time in novel zone, NPP test0.30.41.50.80.6-0.6-0.5-1.2-0.10.2-0.3-1.0-0.8-0.1-0.40.2-0.1
Total zone transitions, NPP test1.32.04.21.91.9-1.9-1.9-2.1-1.8-0.4-0.5-1.7-0.6-0.5-1.20.6-0.3
Total locomotion distance, NPP test0.40.51.30.10.2-0.2-0.1-0.5-0.30.60.8-1.2-0.8-1.0-1.01.0-1.1
Locomotion velocity, NPP test0.30.51.50.30.3-0.3-0.2-0.6-0.30.60.7-1.2-0.8-0.8-0.90.9-1.0
Intraocular pressure0.60.93.2-1.0-1.21.21.30.71.80.1-0.41.10.10.51.0-0.90.8
Delta distance traveled before/after self-admin0.80.92.4-0.5-0.30.30.41.3-0.1-0.7-0.11.21.41.31.6-1.30.8
Delta ambulatory time before/after self-admin0.50.82.1-0.3-0.10.10.21.1-0.4-0.9-0.21.21.51.21.4-1.30.9
Parametrial fat weight2.66.210.0-2.9-3.03.03.01.63.23.12.7-0.6-2.1-2.4-1.32.0-2.3
Pavlov. Cond. lever latency0.30.40.9-0.6-0.50.50.50.80.5-0.20.00.90.60.60.9-0.80.6
Pavlov. Cond. magazine entry latency0.70.93.10.70.5-0.5-0.7-1.3-0.30.80.5-1.8-1.3-0.7-1.01.0-1.0
Pavlov. Cond. change in total contacts0.60.62.40.50.3-0.3-0.3-1.20.21.00.3-1.5-1.3-0.4-0.60.6-0.7
Pavlov. Cond. index score0.20.30.90.70.5-0.5-0.6-0.9-0.30.2-0.2-0.9-0.6-0.1-0.40.3-0.2
Pavlov. Cond. latency score0.20.30.90.50.3-0.3-0.5-0.8-0.30.40.1-0.9-0.7-0.4-0.60.6-0.5
Pavlov. Cond. lever contacts0.30.30.80.30.3-0.3-0.3-0.6-0.30.40.3-0.9-0.7-0.7-0.90.9-0.7
Pavlov. Cond. magazine entry number0.20.31.1-0.8-0.60.60.71.00.30.00.50.70.3-0.5-0.20.3-0.3
Pavlov. Cond. intertrial magazine entries0.40.51.0-0.8-0.80.81.00.71.00.3-0.00.60.20.50.9-0.60.4
Pavlov. Cond. lever-magazine prob. diff.0.40.51.50.80.7-0.7-0.8-1.2-0.40.3-0.1-1.2-0.8-0.2-0.50.5-0.4
Pavlov. Cond. response bias0.20.20.70.60.5-0.5-0.6-0.9-0.20.1-0.3-0.7-0.40.2-0.1-0.00.1
Pavlov. Cond. lever latency0.40.61.8-1.1-0.90.90.91.40.30.40.90.60.60.30.9-0.5-0.2
Pavlov. Cond. magazine entry latency2.23.17.32.62.4-2.4-2.7-2.7-2.2-0.8-1.1-1.7-0.60.2-0.80.20.1
Pavlov. Cond. change in total contacts0.81.96.71.81.6-1.6-1.7-2.6-0.60.1-0.8-1.9-1.4-0.3-1.00.5-0.1
Pavlov. Cond. index score1.42.26.62.11.9-1.9-2.0-2.6-1.2-0.4-1.0-1.7-1.0-0.3-1.20.6-0.0
Pavlov. Cond. latency score1.22.06.01.91.7-1.7-1.8-2.4-1.0-0.3-0.9-1.7-1.1-0.5-1.30.8-0.1
Pavlov. Cond. lever contacts0.40.61.91.10.9-0.9-0.9-1.4-0.3-0.4-0.9-0.7-0.6-0.2-0.80.40.2
Pavlov. Cond. magazine entry number3.95.012.2-3.4-3.23.23.23.52.41.21.81.90.6-0.50.80.1-0.6
Pavlov. Cond. intertrial magazine entries0.30.71.7-1.3-1.21.21.31.11.30.60.60.4-0.1-0.40.10.2-0.3
Pavlov. Cond. lever-magazine prob. diff.1.62.57.52.32.1-2.1-2.2-2.7-1.4-0.5-1.1-1.7-1.0-0.1-1.10.50.1
Pavlov. Cond. response bias1.31.85.11.91.7-1.7-1.9-2.3-1.2-0.6-1.1-1.3-0.8-0.1-1.00.40.2
Time in closed arm before self-admin0.30.61.4-0.4-0.50.50.6-0.31.01.10.6-0.7-1.2-0.9-0.70.7-0.7
Time in closed arm after self-admin0.20.20.6-0.8-0.40.40.70.80.40.50.70.1-0.1-0.5-0.00.3-0.5
Time in open arm before self-admin0.81.03.3-0.7-0.60.60.41.8-0.7-0.70.41.41.71.01.1-1.00.3
Time in open arm after self-admin0.30.31.00.30.1-0.1-0.30.2-0.5-0.7-0.40.60.91.00.7-0.80.7
Bone: periosteal estimation0.81.95.90.10.1-0.1-0.1-1.00.30.90.5-1.6-1.9-2.2-2.42.4-1.5
Bone: periosteal perimeter0.61.33.90.50.4-0.4-0.4-1.20.10.60.2-1.4-1.5-1.6-2.01.8-1.0
Bone: post-yield work5.59.622.30.90.9-0.9-0.6-3.10.32.92.1-4.7-4.5-3.9-4.34.3-3.7
Progressive ratio test 1 active lever presses0.20.40.9-0.5-0.70.70.6-0.00.90.60.3-0.2-0.8-0.7-0.50.7-0.4
Progressive ratio test 1 breakpoint0.20.30.8-0.4-0.60.60.5-0.10.90.60.2-0.3-0.8-0.7-0.50.7-0.4
Progressive ratio test 1 inactive lever presses0.00.10.3-0.2-0.30.30.3-0.00.50.30.0-0.0-0.20.20.3-0.30.1
Progressive ratio test 2 active lever presses1.52.15.6-1.6-1.81.81.80.62.41.71.0-0.3-1.5-1.4-0.61.0-0.9
Progressive ratio test 2 breakpoint1.52.05.6-1.6-1.81.81.80.62.41.60.9-0.2-1.4-1.3-0.61.0-0.8
Progressive ratio test 2 inactive lever presses1.96.115.2-3.2-3.43.43.31.83.93.02.30.1-1.8-1.6-0.11.0-1.4
Incentive Sensitization - Responses0.30.71.7-0.1-0.10.10.2-0.70.50.90.4-1.0-1.3-1.3-1.21.2-0.9
Incentive Sensitization - Breakpoint0.30.71.7-0.3-0.30.30.4-0.50.81.00.5-1.0-1.3-1.3-1.21.2-0.9
Sum of active levers in priming session hrs 5-61.71.66.01.41.2-1.2-1.1-1.4-0.2-1.6-2.40.50.40.90.6-1.12.0
Progressive ratio1.03.06.01.21.1-1.1-1.3-2.2-0.91.00.9-2.4-2.2-2.0-2.42.2-1.8
Food seeking constrained by brief footshock0.00.10.20.10.4-0.4-0.20.2-0.3-0.2-0.20.10.4-0.10.1-0.20.1
Seeking ratio, punishment vs. effort1.22.76.7-1.6-1.31.31.52.60.8-0.6-0.22.42.11.52.2-1.91.2
Retroperitoneal fat weight5.223.447.7-6.9-6.96.96.95.76.24.44.91.8-1.3-2.60.01.8-2.8
Reaction time number correct0.10.51.80.60.5-0.5-0.4-0.2-0.6-1.3-1.10.80.80.50.3-0.50.9
Reaction time mean minus median0.52.98.52.52.3-2.3-2.2-2.9-1.4-0.7-1.4-1.7-0.9-0.3-1.40.30.3
Reaction time mean minus median AUC0.21.43.61.81.6-1.6-1.6-1.9-1.0-0.9-1.3-0.6-0.20.2-0.7-0.20.7
Reaction time num false alarms0.40.72.9-1.0-0.60.60.91.70.0-0.30.51.31.20.50.9-0.60.1
Reaction time num false alarms AUC0.20.41.3-0.30.1-0.10.21.1-0.6-0.70.21.11.20.60.8-0.60.2
Reaction time trials correct on left0.10.51.80.60.5-0.5-0.4-0.2-0.6-1.3-1.10.80.80.50.3-0.50.9
Reaction time trials on left0.20.62.10.70.6-0.6-0.5-0.2-0.7-1.5-1.20.80.80.60.3-0.61.0
Reaction time mean0.10.20.70.40.3-0.3-0.0-0.80.30.4-0.2-0.6-0.60.0-0.2-0.30.1
Reaction time mean AUC0.10.20.80.40.3-0.30.0-0.90.40.70.1-0.8-0.8-0.1-0.3-0.1-0.2
Median of all reaction times0.10.20.7-0.2-0.30.30.6-0.20.80.80.3-0.4-0.6-0.1-0.0-0.2-0.2
Reaction time omissions0.81.23.11.81.6-1.6-1.3-1.7-1.1-0.8-0.9-0.9-0.10.3-0.4-0.30.5
Reaction time false alarm rate0.30.41.7-0.9-0.50.50.71.3-0.00.10.80.80.60.10.5-0.2-0.3
Reaction time premature initiation rate1.62.56.21.81.8-1.8-1.9-0.6-2.5-2.2-1.50.71.71.30.5-0.91.2
Reaction time premature initiations1.54.59.52.42.3-2.3-2.3-0.9-2.9-3.1-2.41.12.31.90.9-1.52.0
Std. dev. reaction times0.30.93.01.51.3-1.3-1.0-1.7-0.5-0.3-0.8-0.9-0.60.0-0.6-0.20.3
Reaction time trials completed0.20.62.10.70.6-0.6-0.5-0.2-0.7-1.5-1.20.80.80.60.3-0.61.0
Reaction time trials AUC0.10.41.70.50.4-0.4-0.3-0.0-0.6-1.3-1.00.80.80.50.2-0.50.8
Run reversals in cocaine runway, females0.70.82.00.20.5-0.5-0.6-0.2-1.10.61.0-1.2-0.6-1.1-1.21.4-1.4
Run reversals in cocaine runway, males0.80.92.9-0.6-0.50.50.61.10.5-0.9-0.81.71.20.81.1-0.91.1
Latency to leave start box in cocaine runway0.71.02.0-0.3-0.20.20.2-0.40.21.21.3-1.3-1.4-1.3-1.11.3-1.4
Latency to leave start box in cocaine runway, F0.30.31.0-0.1-0.20.2-0.0-0.3-0.00.81.0-0.9-0.8-0.3-0.20.5-0.9
Latency to leave start box in cocaine runway, M0.70.62.1-0.00.2-0.20.1-0.30.10.50.4-0.9-0.9-1.5-1.51.3-0.9
Std. dev. time between licks in bursts0.30.61.9-0.3-0.10.10.21.2-0.6-0.9-0.11.41.40.50.7-0.50.5
Total sessions with >9 infusions0.81.02.5-0.1-0.20.20.1-0.50.31.00.8-1.1-1.4-1.6-1.51.6-1.3
Short access day 1 total inactive lever presses1.02.04.0-2.0-1.71.72.01.61.91.51.50.3-0.6-1.1-0.20.7-1.1
Short access day 10 total inactive lever presses0.10.51.5-1.0-0.80.80.91.20.50.50.80.50.40.20.7-0.5-0.2
Short access day 1 total infusions1.32.54.0-1.6-1.51.51.50.71.62.01.9-0.8-1.6-2.0-1.21.9-1.9
Short access day 10 total infusions2.43.98.3-0.8-0.80.80.8-0.61.12.42.1-2.0-2.7-2.9-2.42.8-2.6
Short access total infusions1.72.46.1-0.9-0.90.90.8-0.00.91.71.6-1.3-1.9-2.5-1.92.3-2.1
Short access day 1 locomotion1.01.73.1-1.5-1.51.51.50.81.51.81.6-0.3-1.2-1.3-0.51.2-1.3
Short access day 10 total locomotion0.52.03.6-1.1-1.21.21.20.01.51.91.6-0.9-1.8-1.7-1.21.5-1.6
Short access total locomotion1.42.13.8-1.4-1.51.51.40.41.62.01.7-0.8-1.7-1.7-1.11.6-1.6
One hour access (0.3 mA shock)3.94.79.7-3.0-3.03.03.02.13.12.22.00.6-1.1-1.4-0.11.0-1.2
Compulsive drug intake2.23.26.41.31.6-1.6-1.50.3-2.3-2.4-1.61.12.52.31.6-1.91.7
One hour access (shock baseline)2.46.314.8-3.1-3.33.33.21.53.93.02.3-0.0-2.2-2.1-0.71.6-1.7
Social response proportion0.40.51.31.01.1-1.1-0.8-1.1-0.8-0.3-0.8-0.4-0.20.1-0.3-0.20.3
Social responses0.30.40.70.60.6-0.6-0.5-0.2-0.7-0.8-0.70.60.60.60.4-0.70.8
Social time0.40.61.50.70.6-0.6-0.4-0.2-0.8-1.2-0.90.80.90.70.4-0.80.9
Soleus weight2.36.814.9-3.8-3.93.93.73.33.32.22.51.2-0.4-1.00.40.6-1.2
Bone: stiffness1.83.38.52.22.2-2.2-2.1-2.9-1.4-0.0-0.6-2.3-1.6-1.2-2.21.5-0.7
Tibialis anterior weight5.920.241.46.46.3-6.3-6.3-5.3-5.6-4.8-5.1-0.91.21.2-1.4-0.82.8
Time to tail flick, vehicle, before self-admin0.40.51.50.50.3-0.3-0.5-0.9-0.30.30.1-0.8-0.9-0.9-1.20.9-0.7
Time to tail flick, vehicle, after self-admin0.81.63.70.70.6-0.6-0.8-1.1-1.10.60.9-1.6-1.3-1.7-1.91.9-1.6
Time to tail flick, test, before self-admin2.02.34.8-1.7-1.51.51.51.11.22.02.2-0.5-1.2-1.6-0.81.6-2.0
Time to tail flick, test, after self-admin0.10.10.30.40.2-0.2-0.2-0.50.1-0.3-0.50.0-0.2-0.1-0.10.00.3
Delta time to tail flick, vehicle, before/after SA0.30.30.70.50.6-0.6-0.6-0.5-0.90.10.4-0.8-0.3-0.5-0.70.8-0.7
Delta time to tail flick, test, before/after SA2.83.48.01.81.4-1.4-1.5-1.0-0.9-2.4-2.81.21.62.11.4-2.22.7
Tibia length0.82.16.32.11.8-1.8-1.9-2.5-0.7-1.0-2.0-0.8-0.70.0-0.90.21.0
Ambulatory time before self-admin0.30.92.80.90.8-0.8-0.7-1.7-0.10.6-0.1-1.6-1.4-0.8-1.10.9-0.5
Ambulatory time after self-admin0.20.31.0-0.3-0.30.30.4-0.20.71.00.7-0.8-0.8-0.00.30.1-0.5
Bone: tissue strength0.10.10.20.00.1-0.10.1-0.30.30.30.2-0.4-0.4-0.3-0.20.2-0.2
Total heroin consumption3.13.77.92.82.7-2.7-2.7-2.5-2.5-1.7-1.9-1.10.30.9-0.1-0.61.0
Bone: trabecular number1.01.83.91.21.2-1.2-1.1-2.0-0.60.70.2-2.0-1.7-1.3-1.81.6-1.1
Bone: trabecular spacing0.50.71.9-0.9-0.90.90.91.40.3-0.20.31.00.90.71.1-0.80.2
Bone: trabecular thickness0.50.81.6-0.7-0.50.50.70.10.71.31.2-0.8-1.1-0.9-0.71.0-1.1
Bone: trabecular tissue density1.73.16.9-2.5-2.62.62.52.22.51.21.21.1-0.0-0.10.9-0.2-0.2
Water consumed over 24 hours0.71.32.41.31.1-1.1-1.3-0.7-1.3-1.2-1.10.21.01.61.1-1.41.2
Number of responses in last shaping day0.20.20.6-0.1-0.10.10.10.5-0.1-0.5-0.30.60.80.70.6-0.60.5