Hub : Traits : Tibialis anterior weight : ← : →

chr6:71,700,454-74,473,370

Trait: Tibialis anterior weight

Best TWAS P = 1.52e-09 · Best GWAS P= 4.02e-09 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
BLA	LOC102546421	intron excision ratio	chr6_72408014_72424302	0.26	1	0.19	2.5e-10	5.34	9.35e-08	0.58	FALSE
Brain	LOC102546421	alternative TSS	XR_005505932.2	0.11	9	0.09	7.6e-09	5.35	8.75e-08	0.55	FALSE
Brain	LOC102546421	alternative TSS	XR_010052655.1	0.19	1	0.19	1.4e-17	-5.3	1.15e-07	0.54	FALSE
Brain	LOC120103531	gene expression	LOC120103531	0.31	2219	0.31	6.1e-29	-5.47	4.49e-08	0.55	FALSE
Brain	Prkd1	gene expression	Prkd1	0.22	26	0.1	3.5e-09	-6.04	1.52e-09	0.47	TRUE
Brain	LOC102546421	isoform ratio	XR_005505932.2	0.1	2	0.08	3.7e-08	5.22	1.79e-07	0.55	FALSE
Brain	LOC102546421	isoform ratio	XR_010052655.1	0.17	1	0.18	1.3e-16	-5.28	1.31e-07	0.5	FALSE
Brain	LOC102546421	mRNA stability	LOC102546421	0.28	35	0.33	1.4e-31	5.32	1.05e-07	0.56	FALSE
IC	LOC134479380	alternative polyA	XR_010052657.1	0.15	28	0.11	1.7e-05	-5.35	8.64e-08	0.54	FALSE
IC	LOC134479380	alternative polyA	XR_010052663.1	0.15	31	0.12	1.4e-05	5.35	8.64e-08	0.54	FALSE
IC	Prkd1	gene expression	Prkd1	0.11	1229	0.07	5.0e-04	5.25	1.52e-07	0.34	FALSE
IC	LOC102546421	intron excision ratio	chr6_72408014_72424302	0.37	1	0.19	2.8e-08	5.35	8.83e-08	0.55	FALSE
IL	LOC102546421	alternative TSS	XR_001838399.3	0.31	28	0.29	1.2e-07	-5.3	1.16e-07	0.55	FALSE
IL	LOC120103531	gene expression	LOC120103531	0.22	2219	0.17	5.7e-05	-5.53	3.17e-08	0.52	FALSE
IL	LOC102546421	isoform ratio	XR_001838399.3	0.31	2	0.24	2.0e-06	-5.3	1.18e-07	0.54	FALSE
IL	LOC102546421	mRNA stability	LOC102546421	0.54	292	0.45	3.5e-12	-5.52	3.38e-08	0.55	FALSE
Liver	Prkd1	alternative polyA	XM_063262561.1	0.03	1229	0.02	1.5e-03	-5.42	6.06e-08	0.43	FALSE
Liver	Prkd1	gene expression	Prkd1	0.11	1	0.18	6.4e-20	-5.34	9.33e-08	0.42	FALSE
NAcc	LOC134479380	alternative polyA	XR_010052657.1	0.02	38	0.01	3.3e-03	-5.39	7.01e-08	0.49	FALSE
NAcc	LOC134479380	alternative polyA	XR_010052663.1	0.02	36	0.01	2.6e-03	5.42	5.88e-08	0.5	FALSE
NAcc	LOC102546421	alternative TSS	XR_010052655.1	0.05	51	0.03	1.9e-05	5.54	3.10e-08	0.53	FALSE
NAcc	LOC120103531	gene expression	LOC120103531	0.08	2219	0.1	1.6e-14	-5.43	5.74e-08	0.54	FALSE
NAcc	LOC102546421	isoform ratio	XR_010052655.1	0.04	2260	0.03	4.0e-05	5.54	3.02e-08	0.53	FALSE
NAcc	LOC102546421	intron excision ratio	chr6_72408014_72422522	0.04	1	0.04	7.6e-07	-5.33	1.00e-07	0.55	FALSE
OFC	LOC102546421	alternative TSS	XR_005505932.2	0.21	2260	0.03	8.0e-02	-5.42	5.87e-08	0.27	FALSE
OFC	LOC102546421	isoform ratio	XR_005505932.2	0.29	2260	0.03	6.1e-02	-5.4	6.53e-08	0.23	FALSE
PL	LOC102546421	alternative TSS	XR_010052655.1	0.06	2260	0.06	2.4e-07	5.25	1.49e-07	0.55	FALSE
PL	LOC120103531	gene expression	LOC120103531	0.09	12	0.11	1.8e-12	5.63	1.84e-08	0.52	FALSE
PL	Prkd1	gene expression	Prkd1	0.03	1	0.03	7.3e-04	-5.35	9.01e-08	0.04	FALSE
PL	LOC102546421	isoform ratio	XR_010052655.1	0.06	2260	0.07	7.7e-08	5.44	5.32e-08	0.55	FALSE
PL	LOC134479380	isoform ratio	XR_010052659.1	0.05	2301	0.02	1.1e-03	5.57	2.51e-08	0.43	FALSE
PL	LOC102546421	mRNA stability	LOC102546421	0.25	1	0.3	1.1e-33	-5.35	8.83e-08	0.6	FALSE
PL	LOC134479380	mRNA stability	LOC134479380	0.03	1	0.02	4.6e-03	5.22	1.82e-07	0.04	FALSE
pVTA	Prkd1	isoform ratio	NM_001276715.2	0.03	1229	0.03	3.7e-03	5.31	1.10e-07	0.31	FALSE