Hub : Traits : Tibialis anterior weight : ← : →

chr10:58,773,413-61,528,656

Trait: Tibialis anterior weight

Best TWAS P=5.84e-11 · Best GWAS P=1.49e-10 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Slc43a2	alternative polyA	NM_001105812.1	0.15	1035	0.07	1.3e-08	-5.61	2.04e-08	0.78	FALSE
Adipose	Slc43a2	alternative polyA	XM_039085518.1	0.15	1035	0.07	1.8e-08	5.62	1.89e-08	0.78	FALSE
Adipose	Slc43a2	alternative polyA	NM_001105812.1	0.12	1	0.05	1.6e-06	6.32	2.57e-10	0.81	FALSE
Adipose	Slc43a2	alternative polyA	XM_039085518.1	0.12	1	0.05	1.5e-06	-6.32	2.57e-10	0.81	FALSE
Adipose	Mettl16	alternative TSS	XM_056984673.1	0.03	1	0.01	6.8e-02	-5.6	2.17e-08	0.03	FALSE
Adipose	Mettl16	alternative TSS	XM_056984674.1	0.03	1	0.01	8.4e-03	5.6	2.17e-08	0.03	FALSE
Adipose	Ccdc92b	gene expression	Ccdc92b	0.18	91	0.12	7.2e-13	-5.18	2.26e-07	0.57	FALSE
Adipose	Sgsm2	gene expression	Sgsm2	0.11	819	0.09	1.6e-10	-5.23	1.66e-07	0.7	FALSE
Adipose	Slc43a2	isoform ratio	NM_001105812.1	0.16	1035	0.06	6.6e-07	-5.85	4.79e-09	0.78	FALSE
Adipose	Slc43a2	isoform ratio	XM_006246893.4	0.04	1	0.02	1.9e-03	-6.32	2.57e-10	0.08	FALSE
Adipose	Myo1c	intron excision ratio	chr10_60499487_60505081	0.08	1	0.03	1.2e-04	-6.29	3.10e-10	0.32	FALSE
Adipose	Ccdc92b	mRNA stability	Ccdc92b	0.08	1165	0.03	3.1e-04	5.65	1.60e-08	0.86	FALSE
Adipose	Crk	mRNA stability	Crk	0.18	23	0.14	8.2e-16	6.15	7.72e-10	0.8	FALSE
Adipose	Mettl16	mRNA stability	Mettl16	0.07	1	0.03	4.4e-04	5.99	2.12e-09	0.08	FALSE
Adipose	Sgsm2	mRNA stability	Sgsm2	0.02	26	0.01	5.3e-02	5.47	4.47e-08	0.47	FALSE
BLA	Mettl16	alternative polyA	NM_001402033.1	0.52	734	0.27	1.8e-14	5.65	1.60e-08	0.87	FALSE
BLA	Mettl16	alternative polyA	XM_056984674.1	0.52	164	0.25	6.7e-14	6.14	8.40e-10	0.87	FALSE
BLA	Mettl16	alternative polyA	NM_001402033.1	0.56	734	0.25	1.7e-13	5.44	5.46e-08	0.87	FALSE
BLA	Mettl16	alternative polyA	XM_056984674.1	0.55	734	0.24	6.5e-13	-5.44	5.46e-08	0.87	FALSE
BLA	Rap1gap2	alternative TSS	NM_001401654.1	0.08	1	0.04	4.8e-03	6.03	1.67e-09	0.06	FALSE
BLA	Crk	gene expression	Crk	0.16	1	0.11	1.5e-06	-6.24	4.32e-10	0.56	FALSE
BLA	Inpp5k	gene expression	Inpp5k	0.2	1	0.17	1.7e-09	-6.28	3.46e-10	0.79	FALSE
BLA	Rap1gap2	gene expression	Rap1gap2	0.24	1	0.19	1.8e-10	-5.75	8.70e-09	0.47	FALSE
BLA	Rtn4rl1	gene expression	Rtn4rl1	0.17	1	0.09	1.4e-05	-6.11	9.72e-10	0.4	FALSE
BLA	Mettl16	isoform ratio	NM_001402033.1	0.43	111	0.29	7.1e-16	-5.97	2.36e-09	0.87	FALSE
BLA	Smyd4	intron excision ratio	chr10_60200371_60201453	0.07	812	0.04	5.6e-03	-6.19	6.16e-10	0.7	FALSE
BLA	Crk	mRNA stability	Crk	0.33	1	0.32	1.1e-17	-6.28	3.41e-10	0.8	FALSE
Brain	Rap1gap2	alternative TSS	XM_008767832.3	0.03	1	0.03	1.3e-03	6.1	1.08e-09	0.09	FALSE
Brain	Crk	gene expression	Crk	0.31	1179	0.27	1.3e-25	6.17	6.82e-10	0.83	FALSE
Brain	Doc2b	gene expression	Doc2b	0.66	71	0.56	3.4e-62	-5.67	1.39e-08	0.84	FALSE
Brain	Mnt	gene expression	Mnt	0.06	1	0.01	5.1e-02	5.81	6.22e-09	0.04	FALSE
Brain	Rap1gap2	gene expression	Rap1gap2	0.39	16	0.53	3.0e-58	6.04	1.51e-09	0.8	FALSE
Brain	Rtn4rl1	gene expression	Rtn4rl1	0.58	1	0.18	1.4e-16	-6.28	3.46e-10	0.78	FALSE
Brain	Serpinf1	gene expression	Serpinf1	0.25	14	0.23	3.4e-21	5.36	8.41e-08	0.03	FALSE
Brain	Slc43a2	gene expression	Slc43a2	0.19	1039	0.2	3.6e-18	5.97	2.44e-09	0.78	FALSE
Brain	Wdr81	gene expression	Wdr81	0.04	988	0.03	1.5e-03	-5.39	7.00e-08	0.53	FALSE
Brain	Rap1gap2	isoform ratio	XM_008767832.3	0.03	1	0.03	1.9e-03	6.1	1.08e-09	0.08	FALSE
Brain	Slc43a2	isoform ratio	XR_005489743.1	0.04	1039	0.03	7.9e-04	-5.85	4.82e-09	0.69	FALSE
Brain	Smyd4	isoform ratio	XM_006246674.4	0.05	812	0.04	1.1e-04	6.24	4.52e-10	0.77	FALSE
Brain	Doc2b	intron excision ratio	chr10_60633027_60636786	0.17	1286	0.09	2.5e-08	-5.82	5.97e-09	0.81	FALSE
Brain	Slc43a2	intron excision ratio	chr10_60406456_60409062	0.04	1039	0.03	9.7e-04	-5.47	4.39e-08	0.54	FALSE
Brain	Slc43a2	intron excision ratio	chr10_60406456_60409631	0.02	1039	0.01	2.4e-02	5.2	1.97e-07	0.3	FALSE
Brain	Smyd4	intron excision ratio	chr10_60200371_60201453	0.13	812	0.11	8.1e-11	-5.87	4.31e-09	0.79	FALSE
Brain	Smyd4	intron excision ratio	chr10_60201227_60201453	0.06	812	0.06	3.1e-06	5.38	7.25e-08	0.57	FALSE
Brain	Ccdc92b	mRNA stability	Ccdc92b	0.06	1	0.05	3.0e-05	-5.69	1.28e-08	0.15	FALSE
Brain	Crk	mRNA stability	Crk	0.46	3	0.27	3.5e-25	6.42	1.33e-10	0.83	FALSE
Brain	Doc2b	mRNA stability	Doc2b	0.65	51	0.43	2.3e-43	6.13	8.97e-10	0.84	FALSE
Brain	LOC102549294	mRNA stability	LOC102549294	0.04	1286	0.03	1.7e-03	-5.36	8.17e-08	0.58	FALSE
Brain	Rap1gap2	mRNA stability	Rap1gap2	0.15	5	0.18	7.8e-17	5.61	1.97e-08	0.83	FALSE
Brain	Serpinf1	mRNA stability	Serpinf1	0.04	3	0.02	4.1e-03	5.51	3.50e-08	0.69	FALSE
Brain	Slc43a2	mRNA stability	Slc43a2	0.11	3	0.1	6.1e-10	-6.26	3.86e-10	0.78	FALSE
Eye	Serpinf1	gene expression	Serpinf1	0.35	1	0.13	4.8e-03	6.32	2.69e-10	0.06	FALSE
Eye	Mettl16	isoform ratio	NM_001402033.1	0.45	171	0.22	2.5e-04	-5.39	7.23e-08	0.4	FALSE
Eye	LOC102549294	mRNA stability	LOC102549294	0.56	15	0.05	6.2e-02	-6.12	9.12e-10	0.24	FALSE
IL	Mettl16	alternative polyA	NM_001402033.1	0.64	13	0.25	1.4e-06	6.21	5.44e-10	0.85	FALSE
IL	Mettl16	alternative polyA	XM_056984674.1	0.69	161	0.23	2.4e-06	6.2	5.71e-10	0.86	FALSE
IL	Mettl16	alternative polyA	NM_001402033.1	0.67	4	0.24	1.4e-06	5.99	2.05e-09	0.82	FALSE
IL	Mettl16	alternative polyA	XM_056984674.1	0.7	134	0.25	1.3e-06	6.1	1.09e-09	0.84	FALSE
IL	Crk	gene expression	Crk	0.16	5	0.05	2.5e-02	6.16	7.14e-10	0.45	FALSE
IL	Doc2b	gene expression	Doc2b	0.24	1286	0.07	8.4e-03	5.39	7.05e-08	0.6	FALSE
IL	Rap1gap2	gene expression	Rap1gap2	0.89	68	0.39	1.8e-10	-6.09	1.11e-09	0.89	FALSE
IL	Rtn4rl1	gene expression	Rtn4rl1	0.34	29	0.19	2.1e-05	6.42	1.38e-10	0.73	FALSE
IL	Mettl16	isoform ratio	NM_001402033.1	0.55	17	0.17	8.2e-05	6.02	1.72e-09	0.78	FALSE
IL	Crk	mRNA stability	Crk	0.22	2	0.12	9.1e-04	6.24	4.25e-10	0.6	FALSE
LHb	Crk	gene expression	Crk	0.39	1179	0.28	2.1e-07	5.97	2.40e-09	0.79	FALSE
LHb	Mettl16	isoform ratio	NM_001402033.1	0.53	30	0.26	8.2e-07	6.28	3.48e-10	0.08	FALSE
Liver	Pitpna	alternative polyA	NM_017231.1	0.02	1073	0.01	2.7e-02	-6.03	1.67e-09	0.48	FALSE
Liver	Slc43a2	alternative polyA	NM_001105812.1	0.03	1	0.02	2.4e-03	5.18	2.28e-07	0.03	TRUE
Liver	Slc43a2	alternative polyA	XM_039085518.1	0.03	1	0.02	2.7e-03	-5.65	1.65e-08	0.03	FALSE
Liver	Slc43a2	alternative polyA	NM_001105812.1	0.03	1	0.01	6.7e-03	5.18	2.28e-07	0.03	FALSE
Liver	Slc43a2	alternative polyA	XM_039085518.1	0.03	1	0.01	7.8e-03	-5.18	2.28e-07	0.03	FALSE
Liver	Rpa1	gene expression	Rpa1	0.13	1	0.09	8.5e-10	-5.82	5.97e-09	0.18	FALSE
Liver	Slc43a2	isoform ratio	NM_001105812.1	0.04	1	0.02	2.7e-03	5.18	2.28e-07	0.03	FALSE
Liver	Smyd4	isoform ratio	NM_001105810.1	0.02	1	0.02	5.6e-03	6.21	5.26e-10	0.03	FALSE
Liver	Slc43a2	intron excision ratio	chr10_60413612_60414748	0.03	1035	0.01	6.7e-03	5.76	8.58e-09	0.43	FALSE
Liver	Smyd4	intron excision ratio	chr10_60200371_60201453	0.02	1	0.01	1.2e-02	6.22	4.82e-10	0.03	FALSE
Liver	Crk	mRNA stability	Crk	0.1	1	0.04	6.0e-05	-6.26	3.86e-10	0.59	FALSE
NAcc	Crk	alternative polyA	XM_006246913.2	0.03	3	0.03	5.0e-04	-5.26	1.41e-07	0.57	FALSE
NAcc	Mettl16	alternative polyA	XM_056984674.1	0.25	98	0.2	6.5e-23	5.61	2.06e-08	0.32	FALSE
NAcc	Mettl16	alternative polyA	NM_001402033.1	0.23	63	0.19	4.0e-21	-5.26	1.47e-07	0.04	FALSE
NAcc	Mettl16	alternative polyA	XM_056984674.1	0.26	5	0.21	1.2e-23	-5.72	1.06e-08	0.84	FALSE
NAcc	Pitpna	alternative polyA	NM_017231.1	0.15	10	0.03	1.7e-04	-5.32	1.04e-07	0.26	FALSE
NAcc	Pitpna	alternative polyA	XM_039085772.1	0.14	2	0.04	1.9e-05	5.48	4.19e-08	0.34	FALSE
NAcc	Crk	gene expression	Crk	0.29	8	0.2	1.7e-22	5.34	9.35e-08	0.43	TRUE
NAcc	Doc2b	gene expression	Doc2b	0.49	1	0.39	1.7e-48	-6.3	3.06e-10	0.84	FALSE
NAcc	Mnt	gene expression	Mnt	0.07	790	0.05	7.2e-07	-6.17	6.96e-10	0.84	FALSE
NAcc	Rap1gap2	gene expression	Rap1gap2	0.06	1165	0.05	1.3e-06	5.93	3.09e-09	0.74	FALSE
NAcc	Rpa1	gene expression	Rpa1	0.02	812	0.01	6.4e-03	-5.33	1.00e-07	0.47	FALSE
NAcc	Slc43a2	gene expression	Slc43a2	0.27	20	0.24	3.7e-27	5.59	2.33e-08	0.01	FALSE
NAcc	Mettl16	isoform ratio	NM_001402033.1	0.26	97	0.18	1.9e-20	-5.24	1.61e-07	0	FALSE
NAcc	Slc43a2	intron excision ratio	chr10_60406456_60409062	0.05	46	0.04	1.5e-05	5.53	3.20e-08	0.17	FALSE
NAcc	Slc43a2	intron excision ratio	chr10_60409073_60409631	0.04	1039	0.03	1.7e-04	-5.43	5.50e-08	0.63	FALSE
NAcc	Smyd4	intron excision ratio	chr10_60200371_60201453	0.09	164	0.09	3.5e-10	6.55	5.84e-11	0.65	TRUE
NAcc	Crk	mRNA stability	Crk	0.22	20	0.21	2.9e-24	6.22	5.09e-10	0.82	FALSE
NAcc	Doc2b	mRNA stability	Doc2b	0.04	1286	0.03	4.8e-04	-6.06	1.33e-09	0.78	FALSE
OFC	Mettl16	alternative polyA	NM_001402033.1	0.4	200	0.26	6.8e-07	-6.12	9.13e-10	0.86	FALSE
OFC	Mettl16	alternative polyA	XM_056984674.1	0.38	153	0.25	1.2e-06	6.14	8.28e-10	0.85	FALSE
OFC	Mettl16	alternative polyA	NM_001402033.1	0.37	203	0.24	2.5e-06	-6.06	1.35e-09	0.84	FALSE
OFC	Mettl16	alternative polyA	XM_056984674.1	0.36	734	0.23	3.9e-06	-5.93	3.01e-09	0.84	FALSE
OFC	Crk	gene expression	Crk	0.32	1179	0.26	5.4e-07	6.04	1.56e-09	0.8	FALSE
OFC	Rap1gap2	gene expression	Rap1gap2	0.63	35	0.5	1.4e-13	5.59	2.24e-08	0.78	FALSE
OFC	Rph3al	gene expression	Rph3al	0.25	48	0.17	6.6e-05	-6.33	2.44e-10	0.78	FALSE
OFC	Rtn4rl1	gene expression	Rtn4rl1	0.13	55	0.08	7.3e-03	-5.45	5.07e-08	0.47	TRUE
OFC	Serpinf1	gene expression	Serpinf1	0.15	922	0.1	2.4e-03	-6.24	4.47e-10	0.65	FALSE
OFC	Mettl16	isoform ratio	NM_001402033.1	0.3	734	0.11	1.5e-03	5.27	1.39e-07	0.57	FALSE
OFC	Crk	mRNA stability	Crk	0.17	5	0.16	1.1e-04	-5.85	5.03e-09	0.55	FALSE
PL	Mettl16	alternative polyA	NM_001402033.1	0.3	103	0.26	2.5e-28	-5.43	5.64e-08	0.02	FALSE
PL	Pitpna	alternative polyA	NM_017231.1	0.07	1075	0.06	7.2e-07	-5.35	8.97e-08	0.64	FALSE
PL	Pitpna	alternative polyA	XM_039085772.1	0.07	1075	0.06	6.2e-07	5.3	1.15e-07	0.64	FALSE
PL	Rap1gap2	alternative TSS	NM_001401654.1	0.04	1	0.04	6.4e-05	6.01	1.90e-09	0.41	FALSE
PL	Rap1gap2	alternative TSS	XM_008767832.3	0.04	1165	0.02	3.2e-03	-5.76	8.49e-09	0.7	FALSE
PL	Rap1gap2	alternative TSS	XM_039086003.1	0.05	1165	0.04	7.3e-05	5.52	3.33e-08	0.66	FALSE
PL	Rph3al	alternative TSS	NM_133591.2	0.02	220	0.03	3.3e-04	5.26	1.45e-07	0.02	FALSE
PL	Crk	gene expression	Crk	0.22	1179	0.22	1.3e-23	6.25	4.05e-10	0.82	FALSE
PL	Doc2b	gene expression	Doc2b	0.28	1	0.17	2.1e-18	-6.3	3.06e-10	0.84	FALSE
PL	Hic1	gene expression	Hic1	0.03	739	0.02	1.2e-03	-5.71	1.10e-08	0.61	FALSE
PL	Inpp5k	gene expression	Inpp5k	0.07	74	0.08	8.4e-09	-5.34	9.42e-08	0	FALSE
PL	Rap1gap2	gene expression	Rap1gap2	0.4	1	0.4	4.7e-47	-5.92	3.17e-09	0.7	FALSE
PL	Rph3al	gene expression	Rph3al	0.59	44	0.27	4.2e-29	5.18	2.17e-07	0.01	FALSE
PL	Rtn4rl1	gene expression	Rtn4rl1	0.1	1	0.1	7.5e-11	-5.89	3.80e-09	0.27	FALSE
PL	Inpp5k	isoform ratio	NM_001013859.1	0.05	135	0.03	2.0e-04	-5.98	2.17e-09	0.78	FALSE
PL	Inpp5k	isoform ratio	XM_039085519.1	0.04	69	0.03	3.3e-04	5.94	2.82e-09	0.76	FALSE
PL	Mettl16	isoform ratio	NM_001402033.1	0.33	734	0.28	1.0e-30	5.3	1.18e-07	0.88	FALSE
PL	Rap1gap2	isoform ratio	NM_001401654.1	0.04	1	0.05	2.2e-06	6.01	1.90e-09	0.69	FALSE
PL	Rap1gap2	isoform ratio	XM_008767832.3	0.02	1165	0.01	1.8e-02	-5.79	7.16e-09	0.49	FALSE
PL	Rap1gap2	isoform ratio	XM_039086003.1	0.05	1165	0.03	7.1e-04	5.26	1.45e-07	0.55	FALSE
PL	Rap1gap2	intron excision ratio	chr10_59356749_59394399	0.08	6	0.09	7.0e-10	5.25	1.56e-07	0.4	FALSE
PL	Ccdc92b	mRNA stability	Ccdc92b	0.03	3	0.03	2.0e-04	6.1	1.09e-09	0.64	FALSE
PL	Crk	mRNA stability	Crk	0.26	10	0.29	1.9e-32	6.19	6.07e-10	0.82	FALSE
PL	Myo1c	mRNA stability	Myo1c	0.03	1	0.02	3.4e-03	6.31	2.73e-10	0.07	FALSE
PL	Rap1gap2	mRNA stability	Rap1gap2	0.09	36	0.11	7.0e-12	5.65	1.64e-08	0.57	FALSE
pVTA	Rph3al	alternative TSS	XM_008767941.3	0.19	1	0.1	5.4e-05	-6.31	2.73e-10	0.24	FALSE
pVTA	Crk	gene expression	Crk	0.15	1179	0.15	6.3e-07	5.84	5.25e-09	0.78	FALSE
pVTA	Slc43a2	gene expression	Slc43a2	0.16	1039	0.14	1.1e-06	5.31	1.11e-07	0.65	FALSE
pVTA	Smyd4	intron excision ratio	chr10_60200371_60201453	0.12	1	0.09	9.2e-05	-6.29	3.22e-10	0.76	FALSE
pVTA	Crk	mRNA stability	Crk	0.21	1	0.18	2.1e-08	-5.17	2.29e-07	0.01	FALSE
RMTg	Mettl16	alternative polyA	XM_056984674.1	0.27	734	0.1	1.4e-03	-5.54	3.02e-08	0.66	FALSE
RMTg	Crk	gene expression	Crk	0.18	13	0.11	6.7e-04	6.26	3.86e-10	0.61	FALSE