Hub : Traits : TA weight in grams : ← →

chr7:130,684,861-134,288,889

Best TWAS P=1.237246e-10 · Best GWAS P=1.336057e-10 conditioned to NaN

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	Adipose	Scn8a	gene expression	ENSRNOG00000005309	0.66	0.63	top1	1	0.63	1.7e-89	-6.3	6.3	4.1e-10	-0.95	0.23	0.77	FALSE
2	Adipose	Atg101	gene expression	ENSRNOG00000007756	0.08	0.04	blup	1112	0.04	2.4e-05	-6.2	6.4	1.3e-10	-0.99	0.48	0.52	FALSE
3	Adipose	Krt86	gene expression	ENSRNOG00000008367	0.03	0.01	blup	1318	0.01	5.1e-02	-6.1	6.2	4.4e-10	-0.98	0.43	0.52	FALSE
4	Adipose	Slc11a2	gene expression	ENSRNOG00000019550	0.41	0.16	lasso	56	0.22	4.7e-24	-5.0	-5.5	4.2e-08	0.75	0.35	0.65	FALSE
5	Adipose	Krt80	gene expression	ENSRNOG00000025994	0.11	0.02	blup	1100	0.03	1.2e-04	-6.0	6.3	2.7e-10	-0.93	0.48	0.51	FALSE
6	Adipose	Acvrl1	gene expression	ENSRNOG00000028713	0.06	0.02	enet	258	0.03	1.1e-04	-6.3	-5.1	3.1e-07	0.12	0.38	0.57	TRUE
7	Adipose	Slc4a8	gene expression	ENSRNOG00000028879	0.09	0.10	blup	1377	0.10	1.1e-11	-5.3	5.7	1.1e-08	-0.91	0.89	0.11	FALSE
8	Adipose	Krt1	gene expression	ENSRNOG00000028996	0.04	0.04	top1	1	0.04	2.8e-05	-5.3	5.3	1.3e-07	-0.93	0.27	0.02	FALSE
9	Adipose	Krt79	gene expression	ENSRNOG00000058340	0.12	0.20	lasso	34	0.21	1.0e-22	-5.2	5.4	5.4e-08	-0.88	0.99	0.01	FALSE
10	Adipose	NA	gene expression	ENSRNOG00000065340	0.05	0.04	top1	1	0.04	1.4e-05	-6.1	-6.1	1.1e-09	0.98	0.22	0.12	FALSE
11	Adipose	NA	gene expression	ENSRNOG00000070769	0.26	0.17	top1	1	0.17	4.7e-18	-5.2	5.2	2.3e-07	-0.85	0.98	0.02	FALSE
12	Adipose	Mettl7a	isoform ratio	ENSRNOT00000052075	0.04	0.01	blup	1594	0.03	3.1e-04	-4.4	5.1	3.1e-07	-0.73	0.48	0.47	FALSE
13	Adipose	Scn8a	isoform ratio	ENSRNOT00000008160	0.06	0.02	blup	1327	0.04	2.3e-05	-4.7	5.9	3.6e-09	-0.94	0.33	0.66	FALSE
14	Adipose	Csad	isoform ratio	ENSRNOT00000016205	0.09	0.03	lasso	5	0.04	1.9e-05	-4.0	6.3	3.2e-10	-0.93	0.68	0.31	FALSE
15	BLA	Krt86	gene expression	ENSRNOG00000008367	0.08	0.11	top1	1	0.11	1.6e-06	-5.1	-5.1	3.0e-07	0.97	0.67	0.01	FALSE
16	BLA	Krt1	gene expression	ENSRNOG00000028996	0.23	0.27	lasso	15	0.28	4.3e-15	-6.0	5.7	9.4e-09	-0.97	0.62	0.38	FALSE
17	BLA	Galnt6	gene expression	ENSRNOG00000033059	0.42	0.37	blup	1453	0.46	8.1e-27	-6.1	5.9	3.7e-09	-0.87	0.26	0.74	FALSE
18	BLA	Atg101	intron excision ratio	chr7:132398752:132401420	0.06	0.04	blup	1112	0.04	4.0e-03	-6.0	-6.1	1.2e-09	0.98	0.52	0.40	FALSE
19	BLA	Atg101	intron excision ratio	chr7:132398752:132401715	0.08	0.07	top1	1	0.07	1.5e-04	-6.3	6.3	2.9e-10	-0.98	0.11	0.16	FALSE
20	BLA	Atg101	intron excision ratio	chr7:132401594:132401715	0.07	0.02	enet	50	0.03	9.4e-03	-6.3	-6.1	1.3e-09	-0.15	0.41	0.40	TRUE
21	BLA	Scn8a	mRNA stability	ENSRNOG00000005309	0.05	0.02	blup	1331	0.05	8.9e-04	3.8	6.0	2.5e-09	-0.82	0.44	0.37	FALSE
22	Brain	Atg101	gene expression	ENSRNOG00000007756	0.06	0.05	top1	1	0.05	1.0e-05	-6.3	6.3	2.9e-10	-0.98	0.23	0.39	FALSE
23	Brain	Krt1	gene expression	ENSRNOG00000028996	0.12	0.13	top1	1	0.13	5.1e-12	-6.1	6.1	1.2e-09	-0.96	0.58	0.42	FALSE
24	Brain	Galnt6	gene expression	ENSRNOG00000033059	0.47	0.44	enet	73	0.62	3.8e-73	-5.4	5.7	1.4e-08	-0.81	0.30	0.70	FALSE
25	Brain	NA	gene expression	ENSRNOG00000065340	0.07	0.06	blup	987	0.08	6.2e-08	-5.0	-5.9	2.7e-09	0.98	0.52	0.48	FALSE
26	Brain	Dazap2	intron excision ratio	chr7:131716432:131717118	0.05	0.02	blup	1583	0.04	6.2e-05	-6.2	5.6	1.9e-08	-0.83	0.36	0.64	FALSE
27	Brain	Dazap2	intron excision ratio	chr7:131717363:131718880	0.04	0.01	blup	1583	0.03	1.2e-03	-6.2	-5.6	2.4e-08	0.81	0.39	0.57	FALSE
28	Brain	Atg101	intron excision ratio	chr7:132398752:132401420	0.04	0.03	blup	1112	0.05	2.8e-05	-6.3	-6.1	1.2e-09	0.98	0.50	0.49	FALSE
29	Brain	Atg101	intron excision ratio	chr7:132398752:132401715	0.08	0.09	top1	1	0.09	2.2e-08	-5.2	5.2	2.3e-07	-0.98	0.98	0.00	FALSE
30	Brain	Igfbp6	mRNA stability	ENSRNOG00000010977	0.03	0.02	blup	1027	0.02	3.6e-03	-4.2	5.9	4.7e-09	-0.85	0.44	0.40	TRUE
31	Brain	Tfcp2	mRNA stability	ENSRNOG00000032395	0.11	0.11	top1	1	0.11	4.6e-10	-5.5	-5.5	4.5e-08	0.83	0.89	0.11	FALSE
32	Brain	NA	mRNA stability	ENSRNOG00000070769	0.13	0.04	top1	1	0.04	6.4e-05	-6.3	-6.3	4.1e-10	0.88	0.08	0.64	FALSE
33	Eye	NA	gene expression	ENSRNOG00000008057	0.84	0.05	blup	1127	0.06	4.5e-02	-6.3	5.8	5.0e-09	-0.89	0.20	0.26	TRUE
34	Eye	Krt4	gene expression	ENSRNOG00000032332	0.32	0.05	blup	1107	0.12	6.6e-03	-5.3	-5.6	1.6e-08	0.82	0.24	0.18	FALSE
35	Eye	Krt6a	gene expression	ENSRNOG00000068586	0.66	0.20	lasso	24	0.22	2.8e-04	-6.2	6.2	4.4e-10	-0.97	0.46	0.38	FALSE
36	Eye	NA	gene expression	ENSRNOG00000068784	0.45	0.04	blup	1332	0.11	8.5e-03	-6.2	6.1	1.2e-09	-0.89	0.40	0.27	FALSE
37	Eye	Krt6a	gene expression	ENSRNOG00000070470	0.81	0.28	enet	92	0.28	3.0e-05	-6.1	-6.1	8.5e-10	0.98	0.47	0.44	FALSE
38	IL	Krt1	gene expression	ENSRNOG00000028996	0.13	0.10	top1	1	0.10	2.4e-03	-6.1	6.1	1.0e-09	-0.96	0.07	0.06	FALSE
39	IL	Krt77	gene expression	ENSRNOG00000036865	0.19	0.04	blup	1261	0.06	1.7e-02	-5.0	-5.7	1.3e-08	0.83	0.33	0.17	FALSE
40	IL	NA	gene expression	ENSRNOG00000070769	0.47	0.21	blup	1606	0.28	2.2e-07	4.1	5.8	5.3e-09	-0.81	0.64	0.32	FALSE
41	LHb	Dazap2	gene expression	ENSRNOG00000004628	0.36	0.11	blup	1577	0.17	6.3e-05	-5.2	5.3	9.8e-08	-0.86	0.34	0.53	TRUE
42	LHb	Galnt6	gene expression	ENSRNOG00000033059	0.68	0.14	enet	9	0.31	4.3e-08	-5.2	5.7	1.6e-08	-0.79	0.44	0.55	FALSE
43	LHb	Krt77	gene expression	ENSRNOG00000036865	0.16	0.06	enet	5	0.09	3.4e-03	-5.1	-5.6	1.9e-08	0.87	0.47	0.33	FALSE
44	LHb	NA	gene expression	ENSRNOG00000065340	0.22	0.22	top1	1	0.22	7.4e-06	-6.1	-6.1	1.1e-09	0.98	0.07	0.06	FALSE
45	Liver	Atg101	gene expression	ENSRNOG00000007756	0.02	0.01	blup	1112	0.01	2.2e-02	-6.1	6.1	1.2e-09	-0.98	0.37	0.33	FALSE
46	Liver	Krt71	gene expression	ENSRNOG00000049495	0.23	0.10	enet	26	0.11	6.6e-12	-6.0	-6.4	1.2e-10	0.87	0.42	0.58	TRUE
47	Liver	NA	gene expression	ENSRNOG00000070294	0.06	0.06	top1	1	0.06	5.9e-07	-5.5	-5.5	3.4e-08	0.97	0.84	0.02	FALSE
48	Liver	Prr13	isoform ratio	ENSRNOT00000113574	0.05	0.03	enet	5	0.04	2.9e-05	-4.4	-5.3	1.5e-07	0.82	0.29	0.70	FALSE
49	Liver	Atg101	intron excision ratio	chr7:132398752:132401420	0.02	0.01	blup	1112	0.02	4.9e-03	-5.5	-5.9	4.1e-09	0.98	0.42	0.27	FALSE
50	Liver	Atg101	intron excision ratio	chr7:132398752:132401715	0.03	0.02	enet	17	0.03	6.5e-04	-6.1	6.0	1.5e-09	-0.97	0.52	0.43	FALSE
51	Liver	Atg101	mRNA stability	ENSRNOG00000007756	0.04	0.05	top1	1	0.05	3.2e-06	-5.8	-5.8	5.2e-09	0.98	0.42	0.06	FALSE
52	NAcc	Krt1	gene expression	ENSRNOG00000028996	0.42	0.20	lasso	3	0.20	3.0e-05	-5.3	5.5	4.4e-08	-0.95	0.38	0.52	FALSE
53	NAcc	Galnt6	gene expression	ENSRNOG00000033059	0.30	0.02	blup	1448	0.03	6.1e-02	4.2	5.2	2.2e-07	-0.66	0.36	0.09	FALSE
54	NAcc	Krt71	gene expression	ENSRNOG00000049495	0.23	0.07	blup	1432	0.07	1.0e-02	-6.1	5.9	2.9e-09	-0.96	0.34	0.34	FALSE
55	NAcc	NA	gene expression	ENSRNOG00000070769	0.79	0.19	enet	11	0.25	2.3e-06	-5.1	5.3	1.1e-07	-0.72	0.78	0.13	FALSE
56	NAcc	Slc11a2	intron excision ratio	chr7:131513908:131515584	0.22	0.00	blup	1544	0.01	1.7e-01	3.8	-5.2	1.9e-07	0.71	0.26	0.18	FALSE
57	NAcc	Scn8a	mRNA stability	ENSRNOG00000005309	0.43	0.03	enet	6	0.07	1.1e-02	-6.2	6.3	3.3e-10	-0.80	0.22	0.51	FALSE
58	NAcc2	Tns2	gene expression	ENSRNOG00000010588	0.12	0.06	lasso	10	0.06	3.3e-04	-3.4	-5.2	1.7e-07	-0.35	0.79	0.08	TRUE
59	NAcc2	Krt1	gene expression	ENSRNOG00000028996	0.18	0.21	blup	1333	0.26	4.7e-14	-5.3	5.5	3.9e-08	-0.96	0.61	0.39	FALSE
60	NAcc2	Galnt6	gene expression	ENSRNOG00000033059	0.43	0.32	enet	65	0.49	9.7e-30	-6.1	5.8	7.1e-09	-0.67	0.34	0.66	FALSE
61	NAcc2	Krt71	gene expression	ENSRNOG00000049495	0.14	0.14	blup	1440	0.18	4.7e-10	-6.1	6.2	5.2e-10	-0.97	0.38	0.62	FALSE
62	NAcc2	NA	gene expression	ENSRNOG00000065340	0.11	0.07	top1	1	0.07	1.1e-04	-6.4	-6.4	1.8e-10	0.98	0.07	0.15	FALSE
63	NAcc2	NA	gene expression	ENSRNOG00000068784	0.04	0.02	blup	1385	0.04	4.7e-03	-6.1	6.0	1.7e-09	-0.95	0.46	0.41	FALSE
64	NAcc2	NA	gene expression	ENSRNOG00000070769	0.25	0.20	blup	1611	0.26	2.9e-14	-4.8	5.6	2.2e-08	-0.85	0.70	0.30	FALSE
65	NAcc2	Aaas	intron excision ratio	chr7:133465036:133465316	0.06	0.02	blup	805	0.03	6.9e-03	-5.0	5.1	3.1e-07	-0.77	0.36	0.54	FALSE
66	NAcc2	Krt71	mRNA stability	ENSRNOG00000049495	0.04	0.00	blup	1440	0.01	5.1e-02	-6.1	6.1	9.8e-10	-0.95	0.46	0.27	FALSE
67	OFC	Galnt6	gene expression	ENSRNOG00000033059	0.29	0.11	enet	13	0.16	1.2e-04	4.0	5.1	2.8e-07	-0.64	0.64	0.12	FALSE
68	OFC	Atg101	intron excision ratio	chr7:132398752:132401420	0.12	0.08	top1	1	0.08	6.5e-03	-6.1	-6.1	8.9e-10	0.98	0.06	0.05	FALSE
69	OFC	Atg101	intron excision ratio	chr7:132398752:132401715	0.26	0.18	top1	1	0.18	5.9e-05	-6.1	6.1	8.9e-10	-0.98	0.07	0.06	FALSE
70	PL	NA	gene expression	ENSRNOG00000070769	0.53	0.08	blup	1606	0.27	3.4e-07	4.2	5.5	4.6e-08	-0.72	0.89	0.09	FALSE
71	PL	Atg101	intron excision ratio	chr7:132398752:132401715	0.75	0.07	top1	1	0.06	1.2e-02	-5.2	5.2	2.3e-07	-0.98	0.06	0.05	FALSE
72	PL	Galnt6	mRNA stability	ENSRNOG00000033059	0.28	0.15	top1	1	0.15	2.4e-04	-5.2	5.2	2.2e-07	-0.88	0.08	0.05	FALSE
73	PL2	Csad	alternative polyA	ENSRNOT00000016205	0.25	0.16	lasso	5	0.18	6.4e-10	-4.0	5.8	5.8e-09	-0.88	0.90	0.10	FALSE
74	PL2	Csad	alternative polyA	ENSRNOT00000079678	0.27	0.18	lasso	9	0.18	6.7e-10	-4.0	-5.4	7.5e-08	0.83	0.98	0.02	FALSE
75	PL2	Znf740	gene expression	ENSRNOG00000012192	0.07	0.01	blup	1120	0.03	1.0e-02	-4.0	-5.4	5.8e-08	0.67	0.58	0.26	TRUE
76	PL2	Krt1	gene expression	ENSRNOG00000028996	0.08	0.09	top1	1	0.09	8.2e-06	-6.2	6.2	4.4e-10	-0.94	0.23	0.41	FALSE
77	PL2	Galnt6	gene expression	ENSRNOG00000033059	0.16	0.12	blup	1453	0.16	3.8e-09	-6.1	5.8	6.9e-09	-0.90	0.36	0.64	FALSE
78	PL2	NA	gene expression	ENSRNOG00000065340	0.47	0.02	blup	987	0.03	7.1e-03	-5.4	-5.7	1.4e-08	0.96	0.42	0.50	FALSE
79	PL2	NA	gene expression	ENSRNOG00000070769	0.46	0.34	blup	1611	0.41	3.3e-24	4.1	5.6	2.4e-08	-0.78	0.78	0.22	FALSE
80	PL2	Atg101	intron excision ratio	chr7:132398752:132401715	0.06	0.06	top1	1	0.06	2.3e-04	-6.4	6.4	1.8e-10	-0.98	0.06	0.09	FALSE
81	PL2	Slc11a2	intron excision ratio	chr7:131527869:131538125	0.11	0.09	blup	1550	0.11	2.3e-06	4.1	5.2	2.0e-07	-0.69	0.69	0.31	FALSE
82	PL2	Atf1	mRNA stability	ENSRNOG00000061088	0.21	0.15	enet	38	0.16	3.1e-09	4.3	5.3	1.0e-07	-0.78	0.98	0.02	FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.