Best TWAS P = 3.35e-08 · Best GWAS P= 6.20e-07 conditioned to 1.62e-04
| Tissue | Gene | RNA modality | RNA phenotype | h2 | # weights | Model R2 | Model R2 P | TWAS Z | TWAS P | Coloc P | Joint |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Adipose | Zfyve26 | alternative polyA | NM_001108038.1 | 0.06 | 2510 | 0.02 | 1.4e-03 | -5.52 | 3.35e-08 | 0.67 | TRUE |
| Adipose | Zfyve26 | alternative polyA | XM_063261931.1 | 0.06 | 2510 | 0.02 | 1.6e-03 | 5.52 | 3.44e-08 | 0.67 | FALSE |
| Adipose | Pigh | gene expression | Pigh | 0.18 | 2222 | 0.12 | 4.6e-13 | 5.22 | 1.76e-07 | 0.75 | TRUE |
| Brain | Atp6v1d | mRNA stability | Atp6v1d | 0.07 | 1780 | 0.02 | 2.6e-03 | -5.22 | 1.79e-07 | 0.63 | FALSE |
| OFC | Pals1 | mRNA stability | Pals1 | 0.76 | 1675 | 0.4 | 1.7e-10 | 5.34 | 9.20e-08 | 0.85 | FALSE |
| PL | Pigh | gene expression | Pigh | 0.4 | 2222 | 0.36 | 1.8e-40 | 5.37 | 7.99e-08 | 0.62 | FALSE |
| PL | Pals1 | mRNA stability | Pals1 | 0.68 | 21 | 0.53 | 2.1e-67 | 5.25 | 1.50e-07 | 0.85 | TRUE |
| RMTg | Zfyve26 | gene expression | Zfyve26 | 0.23 | 2510 | 0.06 | 1.4e-02 | -5.23 | 1.73e-07 | 0.33 | FALSE |