Hub : Genes

Fabp5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression Fabp5 0.4 0.14 0.0e+00 0.3 0.32 0.32 0.32 2.6e-33 8.3e-36 4.4e-36 5.3e-36
2 BLA gene expression Fabp5 0.21 0.11 4.5e-09 0.12 0.1 0.1 0.1 1.1e-06 4.8e-06 3.7e-06 3.3e-06
3 IL gene expression Fabp5 0.31 0.14 1.2e-04 0.1 0.1 0.08 0.09 1.9e-03 1.8e-03 5.9e-03 4.0e-03
4 IC gene expression Fabp5 0.56 0.17 1.1e-14 0.23 0.28 0.3 0.28 2.8e-10 2.0e-12 7.4e-13 5.3e-12
5 OFC gene expression Fabp5 0.39 0.17 4.0e-05 0.06 0.12 0.03 0.04 1.4e-02 9.9e-04 8.2e-02 3.7e-02
6 Brain gene expression Fabp5 0.22 0.12 5.3e-14 0.14 0.12 0.13 0.13 1.5e-12 2.2e-11 9.1e-12 7.1e-12
7 NAcc gene expression Fabp5 0.03 0.02 1.2e-04 0.01 0.02 0.02 0.02 3.7e-02 2.2e-04 1.6e-03 1.7e-03
8 Liver gene expression Fabp5 0.05 0.03 2.4e-04 0.01 0.02 0.02 0.02 5.2e-02 1.6e-03 1.1e-03 1.6e-03
9 Adipose gene expression Fabp5 0.21 0.09 0.0e+00 0.13 0.17 0.17 0.16 1.9e-14 4.0e-18 1.1e-18 1.6e-17
10 NAcc alternative TSS XM_063281209.1 0.03 0.02 7.5e-03 0.01 0.01 0.01 0.01 1.5e-02 2.3e-02 2.6e-03 8.2e-03
11 pVTA gene expression Fabp5 0.11 0.06 2.8e-05 0.06 0.05 0.06 0.06 9.6e-06 1.0e-04 3.1e-05 1.6e-05
12 NAcc alternative TSS NM_145878.2 0.03 0.02 5.5e-03 0.02 0.01 0.01 0.01 1.6e-03 2.0e-02 2.4e-03 6.1e-03
13 LHb gene expression Fabp5 0.37 0.15 4.5e-04 0.07 0.02 0.06 0.03 8.8e-03 1.3e-01 1.8e-02 6.8e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density0.61.02.1-1.2-1.4-1.1-1.2-0.9-1.3-0.4-0.40.2-1.50.71.01.0
Area under the delay curve0.40.41.20.90.80.70.70.61.10.30.30.00.7-0.5-0.5-0.5
BMI with tail0.72.36.81.91.61.71.02.02.61.51.81.2-0.40.71.01.0
BMI without tail1.23.78.52.32.02.11.42.42.92.02.51.7-0.71.11.31.1
Body weight1.46.011.22.72.22.51.92.83.12.73.32.5-1.52.02.12.0
Weight adjusted by age0.30.41.40.40.50.60.60.60.30.71.20.8-0.50.70.50.6
Bone surface1.22.16.7-1.2-1.9-1.0-1.7-0.8-0.90.10.41.0-2.61.81.81.7
Bone volume1.12.06.5-1.0-1.6-0.9-1.4-0.6-0.80.20.51.1-2.61.81.91.8
Breakpoint value in progressive ratio session0.80.91.31.01.11.20.81.11.01.11.11.1-0.60.70.60.6
Number of licking bursts0.10.20.6-0.6-0.6-0.5-0.7-0.4-0.6-0.3-0.4-0.2-0.30.2-0.0-0.1
Context. condit. distance diff. score0.10.10.3-0.1-0.1-0.10.1-0.2-0.5-0.3-0.4-0.50.5-0.6-0.5-0.5
Locomotion velocity, session 11.21.23.41.51.61.61.81.40.71.30.50.90.20.50.3-0.0
Locomotion distance, session 11.11.42.21.21.21.41.51.30.41.51.01.4-0.71.31.00.8
Locomotion velocity, session 21.51.73.31.71.81.71.81.71.51.51.01.00.10.60.50.4
Locomotion distance, session 21.92.74.11.61.61.81.91.70.72.01.52.0-1.31.91.61.5
Locomotion velocity, session 30.20.21.00.10.0-0.0-0.2-0.00.2-0.20.2-0.40.8-0.3-0.9-1.0
Locomotion distance, session 30.10.10.4-0.4-0.3-0.3-0.4-0.2-0.30.00.10.2-0.70.50.50.4
Stereotopy head waving bouts, day 30.50.51.40.60.20.60.30.50.40.81.21.0-0.71.20.50.6
Stereotopy head waving duration, day 30.40.51.51.00.60.80.60.71.10.61.20.50.30.4-0.3-0.3
Locomotion velocity, session 72.83.18.8-1.7-2.2-1.4-1.6-1.3-1.9-0.20.11.0-3.01.92.12.0
Locomotion distance, session 72.43.07.2-2.4-2.7-2.2-2.1-2.2-2.6-1.4-1.1-0.5-1.30.30.40.3
Stereotopy head waving bouts, day 70.70.81.31.11.11.11.01.10.81.10.90.9-0.30.70.60.6
Stereotopy head waving duration, day 70.70.91.71.21.31.21.11.21.31.00.90.60.20.30.30.3
Locomotion velocity, session 81.92.34.62.12.12.02.11.91.91.51.30.90.60.20.10.1
Locomotion distance, session 80.71.02.51.21.11.31.61.20.31.21.01.0-0.30.80.70.6
Degree of sensitization distance0.30.30.8-0.7-0.8-0.6-0.4-0.8-0.9-0.5-0.4-0.2-0.2-0.0-0.00.0
Degree of sensitization stereotypy1.11.22.51.51.61.51.41.51.31.21.00.80.20.50.30.3
Conditioned locomotion0.10.20.20.50.50.40.50.40.40.40.30.3-0.20.20.40.4
Cocaine response after cond. corrected0.60.81.3-1.1-1.0-1.0-0.9-1.1-1.1-1.0-0.4-0.70.4-0.4-0.9-0.8
Cocaine response after cond. not corrected1.11.32.5-1.5-1.3-1.3-1.2-1.5-1.6-1.2-0.8-0.80.4-0.5-1.0-0.9
Cocaine response before conditioning0.10.10.3-0.4-0.4-0.3-0.5-0.3-0.4-0.1-0.10.1-0.50.30.30.4
Saline control response0.60.82.4-0.1-0.6-0.1-0.60.20.40.51.21.0-1.51.21.21.3
Bone: connectivity density0.91.43.3-1.5-1.8-1.4-1.5-1.3-1.6-0.8-0.8-0.3-1.30.40.80.8
Bone: cortical apparent density0.30.41.40.91.20.81.00.70.80.40.1-0.00.6-0.4-0.1-0.1
Bone: cortical area0.91.42.51.00.50.90.51.21.51.31.61.5-1.21.41.21.1
Bone: cortical porosity0.10.10.4-0.1-0.10.1-0.10.0-0.60.20.10.4-0.30.60.10.2
Bone: cortical porosity0.20.20.50.20.20.40.30.3-0.40.50.20.6-0.40.70.30.3
Bone: cortical thickness1.11.83.31.41.11.41.01.51.61.61.81.6-0.91.41.00.9
Bone: cortical thickness3.23.88.52.62.52.42.32.42.92.01.91.50.30.70.40.4
Bone: cortical tissue density0.30.41.40.91.20.81.00.70.70.4-0.0-0.10.7-0.5-0.2-0.1
Condit. Reinf. active minus inactive responses7.17.910.72.82.73.02.83.12.43.32.43.1-2.22.72.93.0
Condit. Reinf. active-inactive response ratio8.69.212.63.12.93.33.03.32.63.52.63.4-2.32.93.23.1
Condit. Reinf. active responses6.27.610.52.62.42.82.62.92.13.22.43.2-2.42.93.03.0
Condit. Reinf. inactive responses0.10.10.20.30.20.30.40.40.20.50.30.4-0.40.50.50.2
Incentive salience index mean7.18.712.02.92.83.12.93.22.33.52.43.3-2.42.93.13.2
Condit. Reinf. lever presses2.73.85.42.01.92.22.12.21.32.31.32.0-1.51.82.12.2
Condit. Reinf. active minus inactive responses1.51.95.9-0.8-1.3-0.6-1.2-0.3-0.40.41.31.3-2.42.21.71.8
Condit. Reinf. active-inactive response ratio1.21.44.3-0.3-0.7-0.1-0.60.10.00.71.21.3-2.11.91.61.7
Condit. Reinf. active responses1.82.57.6-1.2-1.7-0.9-1.4-0.7-0.90.31.01.3-2.82.31.92.0
Condit. Reinf. inactive responses0.20.20.8-0.3-0.6-0.2-0.2-0.2-0.20.10.30.4-0.90.70.70.8
Condit. Reinf. lever presses0.71.02.9-0.6-1.1-0.5-1.1-0.4-0.00.21.11.0-1.71.61.01.1
Condit. Reinf. lever reinforcers received1.72.37.0-1.2-1.8-0.9-1.5-0.8-0.90.21.01.3-2.62.31.71.9
Conditioned reinforcement - actives1.83.17.5-2.2-2.7-2.1-2.6-1.9-2.1-1.00.1-0.0-2.11.11.01.0
Conditioned reinforcement - inactives0.10.20.6-0.5-0.5-0.3-0.6-0.3-0.3-0.00.40.3-0.80.50.40.5
Conditioned locomotion1.11.53.8-1.4-2.0-1.5-1.9-1.2-1.2-0.60.0-0.0-1.50.90.80.8
Patch foraging indifference point 0 sec0.71.42.0-1.2-1.3-1.4-1.3-1.4-0.5-1.4-1.3-1.30.7-1.2-1.0-1.1
Patch foraging indifference point AUC0.10.10.70.20.50.30.90.1-0.50.0-0.5-0.10.3-0.50.10.0
Delay disc. indifference point, 0s delay0.20.30.7-0.2-0.6-0.5-0.3-0.5-0.3-0.5-0.8-0.80.5-0.4-0.4-0.4
Delay disc. indifference point, 16s delay0.40.41.50.80.80.70.60.71.20.30.50.20.5-0.4-0.4-0.3
Delay disc. indifference point, 2s delay1.71.92.61.30.91.21.11.31.11.61.51.5-1.31.61.61.6
Delay disc. indifference point, 24s delay0.10.10.20.10.30.20.20.20.4-0.00.3-0.00.4-0.4-0.4-0.3
Delay disc. indifference point, 4s delay0.90.92.51.31.31.11.11.11.60.61.00.40.6-0.3-0.3-0.3
Delay disc. indifference point, 8s delay0.40.41.1-0.00.1-0.1-0.1-0.20.1-0.6-0.8-0.61.0-1.0-1.0-1.0
Indifference point function ln k0.10.20.90.2-0.10.1-0.40.21.0-0.00.6-0.20.6-0.1-0.7-0.7
Indifference point function log k0.10.20.90.2-0.10.1-0.40.21.0-0.00.6-0.20.6-0.1-0.7-0.7
Patch foraging total patch changes 0 sec0.71.21.8-0.9-0.9-1.1-1.0-1.1-0.2-1.3-1.2-1.31.0-1.3-1.2-1.3
Patch foraging total patch changes 12 sec0.70.91.9-0.9-0.5-0.8-0.3-1.1-0.9-1.1-1.4-1.11.0-1.2-0.9-1.0
Patch foraging total patch changes 18 sec0.20.31.10.70.80.61.10.40.90.2-0.0-0.00.7-0.4-0.2-0.4
Patch foraging total patch changes 24 sec0.30.61.6-0.4-0.3-0.5-0.0-0.7-0.8-0.8-1.3-0.90.8-1.0-0.7-0.8
Patch foraging total patch changes 6 sec0.30.41.4-0.00.1-0.20.2-0.30.1-0.5-1.1-0.70.8-1.2-0.5-0.6
Patch foraging time to switch 0 sec1.93.85.61.61.51.91.81.91.22.32.02.4-1.92.42.12.1
Patch foraging water rate 0 sec0.61.23.0-0.3-0.3-0.7-0.6-0.70.1-1.1-1.0-1.51.6-1.7-1.5-1.5
Patch foraging water rate 12 sec0.81.62.7-1.4-1.6-1.6-1.5-1.5-1.0-1.4-1.6-1.20.3-0.8-0.7-0.7
Patch foraging water rate 18 sec0.20.31.1-0.6-0.7-0.7-0.6-0.5-0.4-0.5-1.1-0.4-0.4-0.30.40.3
Patch foraging water rate 24 sec0.40.62.0-0.1-0.4-0.5-0.5-0.50.6-0.9-0.5-1.11.1-1.4-0.8-0.9
Patch foraging water rate 6 sec1.11.74.1-1.5-1.9-1.8-2.0-1.6-0.3-1.6-0.5-1.30.2-0.8-0.7-0.8
Seeking ratio, delayed vs. immediate footshock5.87.111.5-3.4-3.4-3.3-3.2-3.3-3.4-2.9-2.6-2.30.4-1.4-1.3-1.4
Distance traveled before self-admin0.40.52.51.00.70.70.30.91.60.61.20.40.1-0.10.00.1
Distance traveled after self-admin0.10.10.3-0.2-0.3-0.3-0.4-0.10.4-0.3-0.1-0.50.4-0.4-0.4-0.3
Extensor digitorum longus weight7.429.249.27.06.56.76.36.87.05.96.04.4-0.32.52.42.3
Bone: elastic displacement0.80.92.70.30.30.60.50.6-0.51.00.81.3-1.21.61.01.3
Bone: elastic work0.70.93.00.30.10.50.10.6-0.31.01.11.3-1.31.70.91.1
Bone: endosteal estimation0.92.06.6-0.1-0.8-0.1-0.70.30.60.91.21.5-2.61.92.32.2
Bone: endosteal perimeter0.20.51.4-0.6-0.9-0.5-0.8-0.4-0.4-0.0-0.10.3-1.20.61.00.8
Epididymis fat weight0.20.51.21.11.10.80.70.90.90.61.00.20.4-0.0-0.1-0.0
Delta time in closed arm before/after self-admin0.50.41.2-0.0-0.4-0.4-0.5-0.30.2-0.6-0.6-1.01.1-0.8-0.9-0.7
Delta time in open arm before/after self-admin0.10.10.4-0.4-0.4-0.2-0.3-0.2-0.3-0.10.10.3-0.70.20.50.3
Diff in mean of infusions in LGA sessions2.63.25.91.71.51.81.41.91.82.02.42.1-1.41.71.71.6
Delay discount exponential model param0.30.31.0-0.7-0.8-0.6-0.6-0.6-1.0-0.2-0.3-0.0-0.70.50.50.5
Extinction: sum of active levers before priming0.30.30.70.40.60.50.40.50.40.50.80.6-0.40.60.40.6
Active lever presses in extinction session 60.30.30.8-0.4-0.2-0.4-0.5-0.5-0.3-0.7-0.2-0.70.6-0.7-0.9-0.8
Bone: final force1.22.03.61.10.61.10.51.31.71.51.91.7-1.51.61.51.4
Bone: final moment1.01.53.30.80.20.70.01.01.51.21.81.5-1.51.51.51.4
Food consumed during 24 hour testing period1.41.93.41.81.71.71.41.71.81.51.51.10.10.90.30.2
Glucose0.91.53.31.61.51.51.31.51.81.21.30.90.40.6-0.1-0.0
Heart weight0.20.30.70.70.70.50.60.40.80.1-0.5-0.30.8-0.6-0.4-0.5
Delay discount hyperbolic model param0.50.61.4-1.1-1.0-0.9-0.9-0.9-1.2-0.6-0.6-0.4-0.40.10.10.1
Intermittent access intake day 1-15 change1.22.55.1-2.2-2.2-2.1-2.2-2.0-1.8-1.7-0.8-1.2-0.1-0.6-0.6-0.6
Intermittent access intake escalation1.73.46.6-2.4-2.4-2.4-2.6-2.3-2.0-2.1-1.0-1.60.1-1.0-0.9-1.0
Intermittent access intake escalation 23.74.37.7-2.8-2.8-2.7-2.7-2.6-2.6-2.2-1.8-1.6-0.2-0.6-0.7-0.8
Intermitt. access day 1 inactive lever presses0.31.33.11.41.51.11.11.01.70.30.2-0.51.7-0.9-1.0-0.9
Intermitt. access day 15 inactive lever presses0.91.75.2-0.20.5-0.10.6-0.5-0.7-0.9-1.6-1.42.3-1.7-2.0-1.9
Intermitt. access escalation Index0.71.03.50.40.80.30.90.10.2-0.4-1.1-1.01.9-1.4-1.4-1.3
Intermittent access day 1 total infusions1.11.75.4-2.0-1.8-1.5-1.4-1.5-2.3-0.9-0.6-0.0-1.30.60.50.5
Intermittent access day 15 total infusions3.85.611.7-3.4-3.3-3.1-3.3-3.0-3.2-2.4-1.4-1.3-0.8-0.4-0.5-0.4
Intermittent access terminal intake (last 3 days)4.35.712.6-3.6-3.2-3.1-3.0-3.0-3.4-2.4-1.9-1.3-0.7-0.4-0.5-0.5
Intermittent access total infusions2.93.57.6-2.8-2.5-2.4-2.5-2.4-2.7-1.8-1.3-0.8-0.9-0.1-0.2-0.2
Intermittent access day 1 locomotion0.40.51.5-1.2-0.9-0.8-0.6-0.8-1.2-0.5-0.4-0.0-0.50.10.10.2
Intermittent access day 15 total locomotion0.20.40.9-0.9-0.9-0.7-0.7-0.7-0.9-0.3-0.1-0.0-0.80.50.50.5
Intermittent access total locomotion0.91.12.8-1.6-1.4-1.3-1.2-1.3-1.7-1.0-0.9-0.5-0.50.10.00.0
Intermittent access standard deviation2.55.29.1-2.9-2.8-2.9-3.0-2.8-2.6-2.6-1.7-2.00.4-1.4-1.3-1.4
Left kidney weight0.20.82.1-0.4-0.4-0.5-0.7-0.60.0-0.9-0.6-1.11.3-1.2-1.4-1.4
Right kidney weight0.10.30.80.60.60.50.40.50.90.10.2-0.20.9-0.5-0.6-0.7
Cocaine induced anxiety0.20.30.70.50.70.50.40.50.90.10.3-0.00.6-0.5-0.5-0.5
Post-drug Anxiety1.41.42.81.61.41.41.31.51.71.31.51.0-0.20.50.50.5
Baseline Anxiety0.70.81.70.80.50.70.60.80.61.01.30.8-0.71.11.11.1
Tail length0.62.45.91.61.51.61.51.71.81.72.41.6-0.71.21.01.0
Length with tail0.62.66.41.51.21.51.41.61.71.72.51.8-1.21.51.51.5
Length without tail0.10.30.80.1-0.4-0.1-0.30.00.10.30.70.5-0.90.80.70.7
Times rat made contact with spout0.00.00.1-0.3-0.2-0.2-0.3-0.10.0-0.2-0.1-0.30.1-0.1-0.2-0.2
Lifetime Intake2.93.67.3-2.7-2.4-2.4-2.3-2.4-2.7-2.0-1.7-1.2-0.2-0.6-0.7-0.7
Liver weight, left0.71.21.61.20.91.10.91.21.21.21.31.2-0.91.11.11.0
Liver weight, right0.40.82.50.30.30.0-0.0-0.00.8-0.60.0-0.91.6-1.4-1.4-1.3
Locomotor activity0.10.21.00.4-0.00.1-0.40.30.70.11.00.10.10.0-0.2-0.2
Locomotor testing distance0.10.21.70.40.10.2-0.10.40.70.31.30.4-0.30.40.30.3
Locomotor testing rearing0.40.91.4-1.2-1.1-1.1-1.1-1.2-1.2-1.1-0.2-0.70.4-0.4-0.7-0.7
Locomotion in novel chamber1.21.52.81.21.11.20.91.31.31.31.71.3-0.91.31.11.0
Locomotion in novel chamber post-restriction0.10.20.9-0.00.1-0.10.1-0.2-0.2-0.4-0.9-0.50.8-0.6-0.6-0.6
Fecal boli incidents, locomotor time 10.10.10.50.30.40.50.70.4-0.00.4-0.20.4-0.10.20.20.2
Change in fecal boli incidents, locomotor task1.71.73.9-1.7-1.7-1.7-2.0-1.7-1.5-1.4-0.5-0.9-0.2-0.5-0.5-0.5
Time >=10cm from walls, locomotor time 10.50.51.1-0.9-1.0-0.9-1.1-0.8-1.0-0.4-0.4-0.0-0.90.50.40.5
Bouts of movement, locomotor time 12.73.16.6-0.7-0.4-1.0-0.7-1.1-0.5-1.7-2.1-2.22.6-2.5-2.5-2.5
Total resting periods, locomotor time 12.12.34.2-0.7-0.5-1.0-0.7-1.1-0.8-1.5-1.8-1.92.0-2.0-2.0-2.0
Rest time, locomotor task time 10.60.71.3-0.3-0.4-0.6-0.4-0.7-0.6-0.9-1.1-1.21.1-1.1-1.0-1.0
Distance moved, locomotor task time 10.10.10.40.30.30.30.10.40.70.30.50.4-0.20.30.20.2
Vertical activity count, locomotor time 10.51.22.50.40.30.60.10.80.91.11.51.4-1.61.41.41.4
Time >=10cm from walls, locomotor time 20.40.61.9-0.3-0.7-0.2-0.4-0.1-0.30.30.50.7-1.41.21.11.2
Bouts of movement, locomotor time 21.01.64.60.20.3-0.1-0.0-0.30.4-0.9-1.1-1.32.1-2.0-2.0-2.0
Total resting periods, locomotor time 21.11.95.20.20.3-0.2-0.1-0.30.4-1.0-1.2-1.42.3-2.2-2.2-2.1
Rest time, locomotor task time 20.30.41.00.20.3-0.0-0.0-0.10.3-0.4-0.2-0.61.0-1.0-1.0-1.0
Distance moved, locomotor task time 20.00.00.1-0.1-0.1-0.1-0.0-0.10.1-0.2-0.2-0.30.4-0.2-0.2-0.2
Vertical activity count, locomotor time 21.21.72.61.41.21.41.31.51.61.51.21.2-0.71.21.21.2
Light reinforcement 10.40.92.41.01.40.91.50.71.10.3-0.5-0.21.2-1.0-0.6-0.6
Light reinforcement 21.32.14.42.02.11.82.01.82.11.40.80.80.40.00.30.4
Bone: marrow area1.02.16.60.1-0.70.1-0.60.50.71.01.31.5-2.62.02.32.2
Bone: maximum diameter0.10.10.50.1-0.10.1-0.10.30.70.30.20.4-0.50.20.60.4
Bone: maximum force1.01.74.01.00.51.00.31.21.51.42.01.7-1.31.81.21.1
Bone: maximum moment0.71.33.50.60.00.6-0.20.81.21.11.91.5-1.41.71.11.0
Mean time between licks in bursts0.71.63.11.00.91.21.01.10.61.51.31.6-1.31.71.41.3
Mean num. licks in bursts0.10.10.30.30.40.30.50.20.60.10.3-0.00.3-0.3-0.1-0.1
Cd content in liver0.60.61.80.60.90.40.40.41.0-0.1-0.6-0.61.3-1.0-1.0-1.0
Co content in liver1.31.54.20.10.1-0.3-0.2-0.40.5-0.9-1.1-1.32.1-1.7-2.0-2.0
Cu content in liver2.73.24.9-2.2-2.0-2.1-1.8-2.2-2.2-2.0-2.0-1.70.5-1.3-1.0-1.2
Fe content in liver0.30.30.7-0.6-0.8-0.5-0.6-0.5-0.8-0.10.30.3-0.80.60.30.5
K content in liver0.70.71.1-1.0-1.0-1.0-0.8-1.1-1.0-1.0-1.0-0.80.1-0.8-0.2-0.3
Mg content in liver0.50.51.0-0.9-1.0-0.9-0.7-0.9-1.0-0.7-0.7-0.5-0.3-0.40.20.1
Mn content in liver0.10.10.5-0.2-0.1-0.10.4-0.1-0.7-0.1-0.7-0.1-0.1-0.30.40.2
Na content in liver0.80.81.4-1.1-1.2-1.1-1.1-1.0-0.8-1.0-1.1-0.8-0.0-0.7-0.1-0.3
Rb content in liver0.20.20.5-0.3-0.2-0.3-0.0-0.4-0.6-0.5-0.7-0.50.6-0.5-0.7-0.6
Se content in liver0.20.21.2-0.4-0.3-0.30.1-0.3-0.6-0.4-1.1-0.50.3-0.6-0.0-0.1
Sr content in liver0.30.30.60.1-0.10.20.20.2-0.40.50.70.5-0.70.80.60.6
Zn content in liver2.83.14.9-2.1-1.9-2.1-1.9-2.1-2.0-2.0-2.2-1.70.5-1.4-1.0-0.9
Bone: minimum diameter3.66.612.21.50.81.71.12.01.72.72.93.3-3.43.53.43.2
Time in familiar zone, hab. session 11.61.53.3-0.7-0.9-1.0-1.2-1.0-0.3-1.3-0.8-1.51.4-1.5-1.6-1.8
Time in novel zone, hab. session 10.10.10.30.10.40.30.50.2-0.30.40.00.5-0.30.50.20.5
Total zone transitions, hab. session 11.01.32.01.31.31.41.41.30.81.41.11.3-0.51.10.80.8
Total locomotion distance, hab. session 10.91.32.30.80.60.90.90.90.21.30.91.4-1.41.51.51.5
Locomotion velocity, hab. session 11.42.03.01.21.01.31.31.30.61.61.21.7-1.51.71.71.7
Time in familiar zone, hab. session 23.74.06.4-1.5-1.3-1.8-1.6-1.9-1.4-2.2-2.0-2.42.1-2.3-2.4-2.5
Time in novel zone, hab. session 22.02.03.80.80.71.10.91.20.91.51.51.7-1.71.71.82.0
Total zone transitions, hab. session 20.20.30.80.50.60.50.80.3-0.30.1-0.3-0.20.9-0.4-0.7-0.7
Total locomotion distance, hab. session 20.20.30.50.50.60.60.70.6-0.00.70.40.6-0.40.60.50.5
Locomotion velocity, hab. session 20.10.20.30.40.40.50.60.4-0.10.50.30.5-0.30.50.50.4
Novel to familiar place preference ratio0.20.30.60.20.10.30.10.40.40.50.80.6-0.60.80.50.8
Novelty place preference0.10.10.4-0.0-0.10.1-0.10.20.30.30.60.4-0.30.50.20.5
Time in novel zone, NPP test0.10.10.30.00.00.1-0.10.20.50.10.60.20.00.2-0.20.1
Total zone transitions, NPP test0.30.51.41.11.01.01.20.80.40.70.20.30.40.00.1-0.1
Total locomotion distance, NPP test0.50.71.10.80.80.91.00.90.21.10.61.0-0.71.00.80.8
Locomotion velocity, NPP test0.40.61.30.50.50.70.80.6-0.20.90.51.0-1.01.11.00.9
Intraocular pressure2.13.14.62.11.72.01.62.02.12.02.11.8-0.81.61.21.2
Delta distance traveled before/after self-admin1.51.63.6-1.8-1.9-1.7-1.6-1.5-1.6-1.2-1.2-0.9-0.40.1-0.10.0
Delta ambulatory time before/after self-admin1.61.94.2-2.0-1.9-1.8-1.6-1.7-2.1-1.3-1.4-1.0-0.40.0-0.1-0.0
Parametrial fat weight0.10.30.50.40.30.40.30.40.30.60.60.6-0.60.70.60.6
Pavlov. Cond. lever latency0.91.12.5-0.8-0.8-0.9-1.0-1.0-0.5-1.1-0.7-1.11.1-1.0-1.4-1.6
Pavlov. Cond. magazine entry latency0.50.71.10.70.60.80.80.90.61.00.50.9-0.81.01.01.0
Pavlov. Cond. change in total contacts2.93.04.11.81.71.91.92.01.72.01.71.7-1.11.51.61.8
Pavlov. Cond. index score0.81.01.51.01.01.11.21.10.81.10.60.9-0.70.71.11.2
Pavlov. Cond. latency score0.60.81.30.91.01.01.11.10.71.00.50.8-0.60.61.01.1
Pavlov. Cond. lever contacts1.51.84.30.90.81.11.11.20.61.41.01.4-1.61.51.92.1
Pavlov. Cond. magazine entry number0.70.81.5-1.1-1.1-1.1-1.2-1.2-0.9-1.1-0.5-0.80.3-0.6-0.7-0.8
Pavlov. Cond. intertrial magazine entries0.40.41.5-0.8-0.9-0.8-0.6-0.8-1.2-0.5-0.6-0.1-0.60.10.40.3
Pavlov. Cond. lever-magazine prob. diff.0.70.91.40.91.01.01.21.10.71.10.60.9-0.60.71.01.2
Pavlov. Cond. response bias1.21.52.61.11.01.21.21.40.81.51.01.3-1.11.31.51.6
Pavlov. Cond. lever latency0.50.71.81.11.31.21.31.10.50.80.20.30.6-0.1-0.1-0.1
Pavlov. Cond. magazine entry latency0.00.00.10.10.10.10.00.20.30.20.20.3-0.30.30.20.2
Pavlov. Cond. change in total contacts1.01.64.20.3-0.20.40.00.50.41.01.31.5-2.02.01.81.9
Pavlov. Cond. index score0.40.61.60.0-0.30.0-0.30.10.40.50.90.9-1.31.21.01.0
Pavlov. Cond. latency score0.30.41.1-0.2-0.5-0.2-0.6-0.20.20.20.70.6-1.11.00.70.7
Pavlov. Cond. lever contacts0.30.41.1-0.7-1.1-0.8-1.0-0.8-0.2-0.50.1-0.0-0.80.30.50.4
Pavlov. Cond. magazine entry number0.20.30.5-0.4-0.2-0.4-0.2-0.4-0.6-0.5-0.5-0.70.7-0.7-0.7-0.7
Pavlov. Cond. intertrial magazine entries0.30.50.80.60.40.70.50.70.20.90.70.8-0.70.90.70.8
Pavlov. Cond. lever-magazine prob. diff.0.30.41.3-0.1-0.4-0.1-0.4-0.00.30.30.70.7-1.11.10.80.8
Pavlov. Cond. response bias0.40.51.7-0.2-0.5-0.2-0.5-0.10.30.20.70.7-1.31.01.01.0
Time in closed arm before self-admin1.01.22.4-1.2-1.0-1.2-0.9-1.2-1.2-1.2-1.6-1.20.7-1.0-0.8-0.8
Time in closed arm after self-admin1.51.63.4-0.6-0.7-0.9-0.8-0.8-0.1-1.3-1.2-1.81.8-1.7-1.7-1.5
Time in open arm before self-admin0.60.62.00.40.10.40.10.50.40.71.41.0-1.11.10.80.9
Time in open arm after self-admin1.01.13.00.90.70.90.51.11.31.01.71.4-1.00.80.90.8
Bone: periosteal estimation1.83.87.80.90.11.00.21.41.71.82.22.4-2.82.62.72.5
Bone: periosteal perimeter0.20.41.10.0-0.40.0-0.30.30.50.40.60.7-1.00.90.90.7
Bone: post-yield work1.82.66.2-2.1-2.3-2.1-2.5-2.0-1.4-1.8-0.8-1.20.3-0.5-1.2-1.2
Progressive ratio test 1 active lever presses1.51.84.0-1.8-1.5-1.6-1.3-1.7-2.0-1.5-1.3-1.10.3-0.7-0.8-0.7
Progressive ratio test 1 breakpoint1.51.84.1-1.8-1.5-1.6-1.3-1.7-2.0-1.5-1.4-1.10.2-0.7-0.7-0.7
Progressive ratio test 1 inactive lever presses0.00.00.1-0.2-0.00.0-0.0-0.0-0.20.10.40.3-0.30.30.20.2
Progressive ratio test 2 active lever presses2.32.76.4-2.2-2.5-2.1-2.5-2.0-2.1-1.3-0.4-0.4-1.40.50.40.4
Progressive ratio test 2 breakpoint2.22.66.0-2.2-2.4-2.1-2.5-1.9-2.0-1.3-0.4-0.4-1.40.50.40.4
Progressive ratio test 2 inactive lever presses0.40.71.9-1.3-1.2-1.1-1.4-1.0-0.8-0.9-0.2-0.4-0.4-0.1-0.2-0.2
Incentive Sensitization - Responses1.31.84.9-1.3-1.7-1.2-1.7-1.0-1.2-0.20.40.6-2.21.61.41.4
Incentive Sensitization - Breakpoint1.31.74.5-1.3-1.8-1.3-1.7-1.0-1.2-0.30.40.5-2.11.51.31.3
Sum of active levers in priming session hrs 5-60.50.41.3-0.5-0.7-0.5-0.7-0.5-0.8-0.0-0.30.4-1.10.80.80.7
Progressive ratio1.52.44.3-1.1-0.7-1.3-1.4-1.2-0.3-1.7-1.0-2.01.9-2.0-2.1-2.0
Food seeking constrained by brief footshock4.04.96.62.32.02.42.12.52.22.62.42.4-1.52.12.02.0
Seeking ratio, punishment vs. effort3.85.47.92.21.72.32.32.31.42.72.12.8-2.22.62.62.6
Retroperitoneal fat weight0.10.50.80.90.80.80.80.80.30.80.60.7-0.30.60.60.7
Reaction time number correct0.40.82.4-0.2-0.7-0.2-0.6-0.0-0.00.40.61.0-1.51.41.31.3
Reaction time mean minus median0.81.94.51.52.11.61.91.10.70.6-0.7-0.12.1-0.7-1.6-1.5
Reaction time mean minus median AUC0.82.15.91.82.42.02.31.61.11.1-0.20.41.6-0.1-1.0-0.9
Reaction time num false alarms0.91.34.5-0.8-1.2-0.6-1.0-0.4-0.60.20.50.8-2.11.51.61.6
Reaction time num false alarms AUC0.81.24.0-1.0-1.3-0.8-1.0-0.6-0.90.00.30.7-2.01.31.51.5
Reaction time trials correct on left0.40.82.4-0.2-0.7-0.2-0.6-0.0-0.00.40.61.0-1.51.41.31.3
Reaction time trials on left0.40.82.4-0.2-0.6-0.1-0.50.10.00.50.61.0-1.61.41.31.3
Reaction time mean0.91.43.81.51.91.71.91.50.81.30.30.80.40.60.00.1
Reaction time mean AUC1.01.64.11.52.01.82.01.60.91.50.41.00.30.80.20.3
Median of all reaction times1.11.62.81.31.71.61.71.50.91.50.71.3-0.51.20.80.9
Reaction time omissions2.13.19.32.32.82.53.12.01.21.80.41.20.90.3-0.00.0
Reaction time false alarm rate0.10.20.4-0.6-0.6-0.5-0.5-0.4-0.5-0.3-0.2-0.2-0.50.10.20.3
Reaction time premature initiation rate2.02.74.2-1.8-1.4-1.8-1.6-1.8-1.3-1.9-2.0-1.91.0-1.6-1.4-1.4
Reaction time premature initiations1.01.82.8-1.7-1.6-1.7-1.7-1.6-1.1-1.5-1.5-1.30.3-0.8-0.7-0.7
Std. dev. reaction times0.71.33.11.11.81.31.60.90.50.5-0.6-0.11.7-0.5-1.4-1.3
Reaction time trials completed0.40.82.4-0.2-0.6-0.1-0.50.10.00.50.61.0-1.61.41.31.3
Reaction time trials AUC0.50.92.6-0.0-0.50.0-0.30.20.20.60.71.2-1.61.51.41.4
Run reversals in cocaine runway, females0.30.30.60.80.80.60.60.70.80.50.50.4-0.0-0.00.30.3
Run reversals in cocaine runway, males2.02.03.11.71.71.81.71.71.51.61.11.4-0.60.91.01.0
Latency to leave start box in cocaine runway0.60.71.5-1.0-1.1-1.0-1.0-1.1-1.2-0.9-0.8-0.70.1-0.3-0.3-0.3
Latency to leave start box in cocaine runway, F2.02.34.3-2.0-2.1-2.0-2.0-1.9-2.1-1.7-1.0-1.2-0.1-0.5-0.5-0.5
Latency to leave start box in cocaine runway, M1.31.33.01.61.61.51.71.41.21.20.60.80.20.40.40.4
Std. dev. time between licks in bursts0.30.41.20.2-0.10.2-0.10.20.30.50.70.7-1.10.91.01.0
Total sessions with >9 infusions1.82.23.5-1.9-1.5-1.7-1.6-1.8-1.8-1.7-1.5-1.30.5-1.2-1.2-1.1
Short access day 1 total inactive lever presses2.12.84.9-1.5-1.1-1.5-1.2-1.7-1.5-1.9-2.2-2.01.5-1.7-1.8-1.8
Short access day 10 total inactive lever presses0.20.51.70.40.30.10.10.10.6-0.3-0.6-0.91.3-0.8-1.0-1.0
Short access day 1 total infusions2.53.34.4-1.9-1.7-2.0-1.8-2.1-2.0-2.1-2.1-1.81.0-1.5-1.6-1.5
Short access day 10 total infusions1.82.35.6-2.2-1.9-1.8-1.7-1.9-2.4-1.6-1.2-0.8-0.2-0.6-0.7-0.6
Short access total infusions1.62.14.3-1.9-1.5-1.7-1.5-1.8-2.1-1.6-1.5-1.10.3-0.8-0.9-0.9
Short access day 1 locomotion0.30.40.7-0.6-0.4-0.6-0.6-0.6-0.1-0.8-0.6-0.70.6-0.8-0.8-0.8
Short access day 10 total locomotion0.10.20.40.30.70.50.60.40.30.20.20.20.4-0.4-0.3-0.3
Short access total locomotion0.20.20.6-0.7-0.6-0.6-0.7-0.6-0.3-0.6-0.3-0.40.1-0.4-0.3-0.3
One hour access (0.3 mA shock)2.83.27.9-2.6-2.8-2.3-2.4-2.2-2.5-1.5-0.7-0.7-1.30.40.40.4
Compulsive drug intake0.30.31.00.90.60.70.60.71.00.50.50.10.4-0.0-0.1-0.0
One hour access (shock baseline)3.24.910.7-3.3-3.2-2.8-2.9-2.7-3.2-1.8-1.3-0.7-1.60.50.40.4
Social response proportion0.20.30.90.50.50.40.40.30.80.00.3-0.10.9-0.4-0.7-0.7
Social responses0.50.61.70.81.00.70.60.61.30.10.6-0.11.2-0.7-0.8-0.9
Social time0.00.10.2-0.10.30.20.40.0-0.20.20.00.4-0.10.40.10.1
Soleus weight0.82.45.81.91.81.91.71.92.41.61.91.3-0.10.80.60.5
Bone: stiffness0.40.61.40.80.50.80.30.81.10.81.20.9-0.40.80.40.2
Tibialis anterior weight7.826.641.56.15.65.95.56.26.45.76.04.7-1.93.23.73.6
Time to tail flick, vehicle, before self-admin0.20.30.5-0.4-0.6-0.5-0.4-0.4-0.7-0.0-0.00.1-0.70.60.60.7
Time to tail flick, vehicle, after self-admin1.41.94.5-1.8-2.0-1.8-2.1-1.7-1.7-1.4-0.7-0.8-0.6-0.2-0.2-0.1
Time to tail flick, test, before self-admin0.40.41.2-0.2-0.2-0.3-0.1-0.3-0.1-0.6-0.4-0.71.0-1.1-1.1-1.0
Time to tail flick, test, after self-admin1.11.12.0-1.4-1.1-1.3-1.2-1.3-1.2-1.2-0.8-0.80.3-0.9-0.8-0.9
Delta time to tail flick, vehicle, before/after SA1.91.83.6-1.9-1.7-1.6-1.8-1.7-1.7-1.4-1.3-0.9-0.2-0.5-0.5-0.4
Delta time to tail flick, test, before/after SA0.00.00.1-0.10.20.0-0.1-0.00.2-0.1-0.00.00.0-0.2-0.1-0.3
Tibia length0.82.14.9-1.7-2.0-1.8-2.2-1.7-1.0-1.6-0.7-1.30.4-0.8-1.0-1.1
Ambulatory time before self-admin0.71.03.51.31.11.10.71.31.90.91.50.7-0.00.10.20.2
Ambulatory time after self-admin0.10.10.4-0.5-0.6-0.4-0.6-0.3-0.2-0.20.0-0.1-0.40.30.20.3
Bone: tissue strength2.42.44.1-1.9-1.8-1.8-1.8-1.8-2.0-1.7-1.5-1.40.5-0.9-1.0-1.1
Total heroin consumption0.50.62.1-0.1-0.10.1-0.20.2-0.10.50.91.1-1.41.21.01.0
Bone: trabecular number0.30.40.9-0.9-0.9-0.8-0.9-0.7-0.8-0.5-0.6-0.2-0.60.10.40.3
Bone: trabecular spacing0.40.51.61.01.20.91.30.70.90.4-0.20.00.6-0.50.0-0.0
Bone: trabecular thickness0.60.81.9-1.0-1.1-0.9-1.4-0.7-0.5-0.20.40.4-1.41.10.70.7
Bone: trabecular tissue density1.42.15.41.82.31.82.11.41.60.90.50.31.6-0.4-1.1-1.0
Water consumed over 24 hours0.10.20.60.50.50.40.20.60.70.40.40.2-0.10.10.30.2
Number of responses in last shaping day0.40.40.9-0.8-0.7-0.8-0.9-0.8-0.2-0.8-0.5-0.70.3-0.6-0.5-0.5