Fabp5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression Fabp5 0.4 0.14 0.0e+00 0.3 0.32 0.32 0.32 2.6e-33 8.3e-36 4.4e-36 5.6e-36
2 BLA gene expression Fabp5 0.21 0.11 4.5e-09 0.12 0.1 0.1 0.1 1.1e-06 4.8e-06 3.7e-06 3.3e-06
3 IL gene expression Fabp5 0.31 0.14 1.2e-04 0.1 0.1 0.08 0.09 1.9e-03 1.8e-03 5.9e-03 3.8e-03
4 IC gene expression Fabp5 0.56 0.17 1.1e-14 0.23 0.28 0.3 0.28 2.8e-10 2.0e-12 7.4e-13 4.8e-12
5 OFC gene expression Fabp5 0.39 0.17 4.0e-05 0.06 0.12 0.02 0.04 1.4e-02 9.9e-04 1.0e-01 3.8e-02
6 Brain gene expression Fabp5 0.22 0.12 5.3e-14 0.14 0.12 0.13 0.13 1.5e-12 2.2e-11 9.0e-12 7.6e-12
7 NAcc gene expression Fabp5 0.03 0.02 1.2e-04 0.01 0.02 0.02 0.02 3.7e-02 2.2e-04 1.6e-03 1.7e-03
8 Liver gene expression Fabp5 0.05 0.03 2.4e-04 0.01 0.02 0.02 0.02 5.2e-02 1.6e-03 1.1e-03 1.6e-03
9 Adipose gene expression Fabp5 0.21 0.09 0.0e+00 0.13 0.17 0.17 0.16 1.9e-14 4.0e-18 1.2e-18 1.8e-17
10 NAcc alternative TSS XM_063281209.1 0.03 0.02 7.5e-03 0.01 0.01 0.01 0.01 1.5e-02 2.3e-02 2.6e-03 8.9e-03
11 pVTA gene expression Fabp5 0.11 0.06 2.8e-05 0.06 0.05 0.06 0.06 9.6e-06 1.0e-04 3.0e-05 1.5e-05
12 NAcc alternative TSS NM_145878.2 0.03 0.02 5.5e-03 0.02 0.01 0.01 0.01 1.6e-03 2.0e-02 2.4e-03 6.0e-03
13 LHb gene expression Fabp5 0.37 0.15 4.5e-04 0.07 0.02 0.06 0.03 8.8e-03 1.3e-01 1.7e-02 6.6e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density0.61.02.11.21.4-1.11.2-0.91.3-0.40.4-0.21.5-0.7-1.0-1.0
Area under the delay curve0.30.41.2-0.9-0.80.7-0.70.6-1.10.3-0.3-0.0-0.70.50.50.5
BMI with tail0.72.46.8-1.9-1.61.7-1.02.0-2.61.5-1.8-1.20.4-0.7-1.0-1.0
BMI without tail0.73.78.5-2.3-2.02.1-1.42.4-2.92.0-2.5-1.70.7-1.1-1.3-1.1
Body weight1.46.011.1-2.7-2.22.5-1.92.8-3.12.7-3.3-2.51.5-2.0-2.1-2.0
Weight adjusted by age0.10.41.3-0.4-0.50.6-0.60.6-0.30.7-1.2-0.80.5-0.7-0.5-0.6
Bone surface1.12.16.61.11.9-1.01.7-0.80.90.1-0.4-1.02.6-1.8-1.8-1.7
Bone volume1.02.06.51.01.6-0.91.4-0.60.80.2-0.5-1.12.6-1.8-1.9-1.8
Breakpoint value in progressive ratio session0.50.91.3-1.0-1.11.2-0.81.1-1.01.1-1.1-1.10.6-0.7-0.6-0.6
Number of licking bursts0.10.20.60.60.6-0.50.7-0.40.6-0.30.40.20.3-0.20.00.1
Context. condit. distance diff. score0.10.10.30.10.1-0.1-0.1-0.20.5-0.30.40.5-0.50.60.50.5
Locomotion velocity, session 11.11.23.3-1.5-1.61.6-1.81.4-0.71.3-0.5-0.9-0.2-0.5-0.30.0
Locomotion distance, session 11.11.42.2-1.2-1.21.4-1.51.3-0.41.5-1.0-1.40.7-1.3-1.0-0.8
Locomotion velocity, session 21.41.73.3-1.7-1.81.7-1.81.7-1.51.5-1.1-1.0-0.1-0.6-0.5-0.4
Locomotion distance, session 21.92.74.1-1.6-1.61.8-1.91.7-0.72.0-1.5-2.01.3-1.9-1.6-1.5
Locomotion velocity, session 30.20.21.0-0.1-0.0-0.00.2-0.0-0.2-0.2-0.20.4-0.80.30.91.0
Locomotion distance, session 30.10.10.40.40.3-0.30.4-0.20.30.0-0.1-0.20.7-0.5-0.5-0.4
Stereotopy head waving bouts, day 30.40.51.4-0.6-0.20.6-0.30.5-0.40.8-1.2-1.00.7-1.2-0.5-0.6
Stereotopy head waving duration, day 30.40.51.5-1.0-0.60.8-0.60.7-1.10.6-1.2-0.5-0.3-0.40.30.3
Locomotion velocity, session 72.83.18.81.72.2-1.41.6-1.31.9-0.2-0.1-0.93.0-1.9-2.1-2.0
Locomotion distance, session 72.43.07.22.42.7-2.22.1-2.22.6-1.41.10.51.3-0.3-0.4-0.3
Stereotopy head waving bouts, day 70.70.81.3-1.1-1.11.1-1.01.1-0.81.1-0.9-0.90.3-0.7-0.6-0.6
Stereotopy head waving duration, day 70.70.91.7-1.2-1.31.2-1.11.2-1.31.0-0.9-0.6-0.1-0.3-0.3-0.3
Locomotion velocity, session 81.92.34.6-2.1-2.12.0-2.11.9-1.91.5-1.3-0.9-0.6-0.2-0.1-0.1
Locomotion distance, session 80.71.02.5-1.2-1.11.3-1.61.2-0.31.2-1.0-1.00.3-0.8-0.7-0.6
Degree of sensitization distance0.30.30.80.70.8-0.60.4-0.80.9-0.50.40.20.20.00.0-0.0
Degree of sensitization stereotypy1.11.22.5-1.5-1.61.5-1.41.5-1.31.2-1.0-0.8-0.2-0.5-0.3-0.3
Conditioned locomotion0.10.20.2-0.5-0.50.4-0.50.4-0.40.4-0.3-0.30.2-0.2-0.4-0.4
Cocaine response after cond. corrected0.50.81.31.11.0-1.00.9-1.11.1-1.00.40.7-0.40.40.90.8
Cocaine response after cond. not corrected0.91.32.51.51.3-1.31.2-1.51.6-1.20.80.9-0.40.51.00.9
Cocaine response before conditioning0.10.10.30.40.4-0.30.5-0.30.4-0.10.1-0.10.5-0.3-0.3-0.4
Saline control response0.60.82.40.10.6-0.10.60.2-0.40.5-1.2-1.01.5-1.2-1.2-1.3
Bone: connectivity density0.91.43.31.51.8-1.41.5-1.31.6-0.80.80.31.3-0.4-0.8-0.8
Bone: cortical apparent density0.30.41.4-0.9-1.20.8-1.00.7-0.80.4-0.10.0-0.60.40.10.1
Bone: cortical area0.91.42.5-1.0-0.50.9-0.51.2-1.51.3-1.6-1.51.2-1.4-1.2-1.1
Bone: cortical porosity0.10.10.40.10.10.10.10.00.60.2-0.1-0.40.3-0.6-0.1-0.2
Bone: cortical porosity0.20.20.5-0.2-0.20.4-0.30.30.40.5-0.2-0.60.4-0.7-0.3-0.3
Bone: cortical thickness1.11.83.3-1.4-1.11.4-1.01.5-1.61.6-1.8-1.60.9-1.4-1.0-0.9
Bone: cortical thickness3.13.88.5-2.6-2.52.4-2.32.4-2.92.0-1.9-1.5-0.3-0.7-0.4-0.4
Bone: cortical tissue density0.30.41.4-0.9-1.20.8-1.00.7-0.70.40.00.1-0.70.50.20.1
Condit. Reinf. active minus inactive responses7.07.910.7-2.8-2.73.0-2.83.1-2.43.3-2.4-3.12.2-2.7-2.9-3.0
Condit. Reinf. active-inactive response ratio8.69.212.6-3.1-2.93.3-3.03.3-2.63.5-2.6-3.42.4-2.9-3.2-3.1
Condit. Reinf. active responses5.97.610.5-2.6-2.42.8-2.62.9-2.13.2-2.4-3.22.4-2.9-3.0-3.0
Condit. Reinf. inactive responses0.10.10.2-0.3-0.20.3-0.40.4-0.20.5-0.3-0.40.4-0.5-0.5-0.2
Incentive salience index mean6.88.712.0-2.9-2.83.1-2.93.2-2.33.5-2.4-3.32.4-2.9-3.1-3.2
Condit. Reinf. lever presses2.53.85.4-2.0-1.92.2-2.12.2-1.32.3-1.3-2.01.5-1.8-2.1-2.2
Condit. Reinf. active minus inactive responses1.21.95.80.71.3-0.61.2-0.30.40.4-1.3-1.32.4-2.2-1.7-1.8
Condit. Reinf. active-inactive response ratio0.91.44.30.30.7-0.10.60.1-0.00.7-1.2-1.32.1-1.9-1.6-1.7
Condit. Reinf. active responses1.72.57.61.21.7-0.91.4-0.70.90.3-1.0-1.32.8-2.3-1.9-2.0
Condit. Reinf. inactive responses0.20.20.80.30.6-0.20.2-0.20.20.1-0.3-0.40.9-0.7-0.7-0.8
Condit. Reinf. lever presses0.71.02.90.61.1-0.51.1-0.40.00.2-1.1-1.01.7-1.6-1.0-1.1
Condit. Reinf. lever reinforcers received1.72.37.01.21.8-0.91.5-0.80.90.2-1.0-1.22.6-2.3-1.7-1.9
Conditioned reinforcement - actives0.83.17.52.22.7-2.12.6-1.92.1-1.0-0.10.02.1-1.1-1.0-1.0
Conditioned reinforcement - inactives0.10.20.60.50.5-0.30.6-0.30.3-0.0-0.4-0.30.8-0.5-0.4-0.5
Conditioned locomotion1.01.53.81.42.0-1.51.9-1.21.2-0.6-0.00.11.5-0.9-0.8-0.8
Patch foraging indifference point 0 sec0.51.42.01.21.3-1.41.3-1.40.5-1.41.21.3-0.71.21.01.1
Patch foraging indifference point AUC0.10.10.7-0.2-0.50.3-0.90.10.50.00.50.1-0.30.5-0.1-0.0
Delay disc. indifference point, 0s delay0.20.30.70.20.6-0.50.3-0.50.3-0.50.80.8-0.50.40.40.4
Delay disc. indifference point, 16s delay0.30.41.5-0.8-0.80.7-0.60.7-1.20.3-0.5-0.2-0.50.40.40.3
Delay disc. indifference point, 2s delay1.71.92.6-1.3-0.91.2-1.11.3-1.11.6-1.5-1.51.3-1.6-1.6-1.6
Delay disc. indifference point, 24s delay0.00.10.2-0.1-0.30.2-0.20.2-0.4-0.0-0.30.0-0.40.40.40.3
Delay disc. indifference point, 4s delay0.80.92.5-1.3-1.31.1-1.11.1-1.60.6-1.0-0.4-0.60.30.30.3
Delay disc. indifference point, 8s delay0.30.41.10.0-0.1-0.10.1-0.2-0.1-0.60.80.6-1.01.01.01.0
Indifference point function ln k0.10.20.9-0.20.10.10.40.2-1.0-0.0-0.60.2-0.60.10.70.7
Indifference point function log k0.10.20.9-0.20.10.10.40.2-1.0-0.0-0.60.2-0.60.10.70.7
Patch foraging total patch changes 0 sec0.41.21.80.90.9-1.11.0-1.10.2-1.31.21.3-1.01.31.21.3
Patch foraging total patch changes 12 sec0.70.91.90.90.5-0.80.3-1.10.9-1.11.41.1-1.01.20.91.0
Patch foraging total patch changes 18 sec0.10.31.1-0.7-0.80.6-1.10.4-0.90.20.00.0-0.70.40.20.4
Patch foraging total patch changes 24 sec0.20.61.60.50.3-0.50.0-0.70.8-0.81.20.9-0.81.00.70.8
Patch foraging total patch changes 6 sec0.20.41.40.0-0.1-0.2-0.2-0.3-0.1-0.51.10.7-0.81.20.50.6
Patch foraging time to switch 0 sec1.03.85.6-1.6-1.51.9-1.81.9-1.22.3-2.0-2.41.9-2.4-2.1-2.1
Patch foraging water rate 0 sec0.31.23.00.30.3-0.70.6-0.7-0.1-1.11.01.5-1.61.71.51.5
Patch foraging water rate 12 sec0.41.62.71.41.6-1.61.5-1.51.0-1.41.61.2-0.30.80.70.7
Patch foraging water rate 18 sec0.10.31.10.60.7-0.70.6-0.50.4-0.51.00.40.40.3-0.4-0.3
Patch foraging water rate 24 sec0.40.62.00.10.4-0.50.5-0.5-0.6-0.90.51.1-1.11.40.80.9
Patch foraging water rate 6 sec1.11.74.11.51.9-1.82.0-1.60.3-1.60.51.3-0.20.80.70.8
Seeking ratio, delayed vs. immediate footshock5.07.111.53.43.4-3.33.2-3.33.4-2.92.62.3-0.41.41.31.4
Distance traveled before self-admin0.30.52.5-1.0-0.70.7-0.30.9-1.60.6-1.2-0.4-0.10.1-0.0-0.1
Distance traveled after self-admin0.10.10.30.20.3-0.30.4-0.1-0.4-0.30.10.5-0.40.40.40.3
Extensor digitorum longus weight7.329.249.2-7.0-6.56.7-6.36.8-7.05.9-6.0-4.40.4-2.5-2.4-2.3
Bone: elastic displacement0.70.92.7-0.3-0.30.6-0.50.60.51.0-0.8-1.31.2-1.6-1.0-1.3
Bone: elastic work0.70.93.0-0.3-0.10.5-0.10.60.31.0-1.1-1.31.3-1.7-0.9-1.1
Bone: endosteal estimation0.82.06.60.10.8-0.10.70.3-0.60.9-1.2-1.42.6-1.9-2.3-2.2
Bone: endosteal perimeter0.20.51.40.60.9-0.50.8-0.40.4-0.00.1-0.31.2-0.6-1.0-0.8
Epididymis fat weight0.10.51.2-1.1-1.10.8-0.70.9-0.90.6-1.0-0.2-0.40.00.10.0
Delta time in closed arm before/after self-admin0.50.41.20.00.4-0.40.5-0.3-0.2-0.60.61.0-1.10.80.90.7
Delta time in open arm before/after self-admin0.10.10.40.40.4-0.20.3-0.20.3-0.1-0.1-0.30.7-0.2-0.5-0.3
Diff in mean of infusions in LGA sessions1.83.25.9-1.7-1.51.8-1.41.9-1.82.0-2.4-2.11.4-1.7-1.7-1.6
Delay discount exponential model param0.20.31.00.70.8-0.60.6-0.61.0-0.20.30.00.7-0.5-0.5-0.5
Extinction: sum of active levers before priming0.20.30.7-0.4-0.60.5-0.40.5-0.40.5-0.8-0.60.4-0.6-0.4-0.6
Active lever presses in extinction session 60.30.30.80.40.2-0.40.5-0.50.3-0.70.20.7-0.60.70.90.8
Bone: final force1.22.03.6-1.1-0.61.1-0.51.3-1.71.5-1.9-1.71.5-1.6-1.5-1.4
Bone: final moment1.01.53.3-0.8-0.20.7-0.01.0-1.51.2-1.8-1.51.5-1.5-1.5-1.4
Food consumed during 24 hour testing period0.91.93.4-1.8-1.71.7-1.41.7-1.81.5-1.5-1.1-0.1-0.9-0.3-0.2
Glucose0.91.53.3-1.6-1.51.5-1.31.5-1.81.2-1.3-0.9-0.4-0.60.10.0
Heart weight0.20.30.7-0.7-0.70.5-0.60.4-0.80.10.50.3-0.80.60.40.5
Delay discount hyperbolic model param0.40.61.41.11.0-0.90.9-0.91.2-0.60.60.40.4-0.1-0.1-0.1
Intermittent access intake day 1-15 change0.52.55.12.22.2-2.12.2-2.01.8-1.70.91.20.10.60.60.6
Intermittent access intake escalation0.63.46.62.42.4-2.42.6-2.32.0-2.11.11.6-0.11.00.91.0
Intermittent access intake escalation 22.54.37.72.82.8-2.72.7-2.62.6-2.21.81.60.10.60.70.8
Intermitt. access day 1 inactive lever presses0.11.33.1-1.3-1.51.1-1.11.0-1.70.3-0.20.5-1.70.91.00.9
Intermitt. access day 15 inactive lever presses0.31.75.20.2-0.5-0.1-0.6-0.50.7-0.91.61.4-2.31.72.01.9
Intermitt. access escalation Index0.31.03.5-0.4-0.80.3-0.90.1-0.2-0.41.11.0-1.91.41.41.3
Intermittent access day 1 total infusions0.61.75.41.91.8-1.51.4-1.52.3-0.90.70.01.3-0.6-0.5-0.5
Intermittent access day 15 total infusions2.35.611.73.43.3-3.13.3-3.03.2-2.41.41.30.80.40.50.4
Intermittent access terminal intake (last 3 days)3.35.712.63.53.2-3.13.0-3.03.4-2.41.91.30.70.40.50.5
Intermittent access total infusions2.93.57.62.82.5-2.42.5-2.42.7-1.81.30.80.90.10.20.2
Intermittent access day 1 locomotion0.30.51.51.20.9-0.80.6-0.81.2-0.50.40.00.5-0.1-0.1-0.2
Intermittent access day 15 total locomotion0.10.40.90.90.9-0.70.7-0.70.9-0.30.10.00.8-0.5-0.5-0.5
Intermittent access total locomotion0.91.12.81.61.4-1.31.2-1.31.7-1.00.90.50.5-0.1-0.0-0.0
Intermittent access standard deviation1.05.29.12.92.8-2.93.0-2.82.6-2.61.72.0-0.41.41.31.4
Left kidney weight0.10.82.10.40.4-0.50.7-0.6-0.0-0.90.61.1-1.31.21.41.4
Right kidney weight0.00.30.8-0.6-0.60.5-0.40.5-0.90.1-0.20.2-0.80.50.60.7
Cocaine induced anxiety0.10.30.7-0.5-0.70.5-0.40.5-0.90.1-0.30.0-0.60.50.50.5
Post-drug Anxiety1.31.42.8-1.6-1.41.4-1.31.5-1.71.3-1.5-1.00.2-0.5-0.5-0.5
Baseline Anxiety0.50.81.7-0.8-0.50.7-0.60.8-0.61.0-1.3-0.80.7-1.1-1.1-1.1
Tail length0.42.45.7-1.6-1.51.6-1.51.7-1.81.7-2.4-1.60.7-1.2-1.0-1.0
Length with tail0.62.66.3-1.5-1.21.5-1.41.6-1.71.7-2.5-1.81.2-1.5-1.5-1.5
Length without tail0.10.30.8-0.10.4-0.10.30.0-0.10.3-0.7-0.50.9-0.8-0.7-0.7
Times rat made contact with spout0.00.00.10.30.2-0.20.3-0.1-0.0-0.20.10.3-0.10.10.20.2
Lifetime Intake2.93.67.32.72.4-2.42.3-2.42.7-2.01.71.20.20.60.70.7
Liver weight, left0.71.21.7-1.2-0.91.1-0.91.2-1.21.2-1.3-1.20.9-1.1-1.1-1.0
Liver weight, right0.40.82.5-0.3-0.30.00.0-0.0-0.8-0.60.00.9-1.61.41.41.3
Locomotor activity0.10.21.0-0.40.00.10.40.3-0.70.1-1.0-0.1-0.1-0.00.20.2
Locomotor testing distance0.10.21.6-0.4-0.10.20.10.4-0.70.3-1.3-0.40.3-0.4-0.3-0.3
Locomotor testing rearing0.20.91.41.21.1-1.11.1-1.21.2-1.10.30.7-0.40.40.70.7
Locomotion in novel chamber1.11.52.8-1.2-1.11.2-0.91.3-1.31.3-1.7-1.30.9-1.3-1.1-1.0
Locomotion in novel chamber post-restriction0.10.20.90.0-0.1-0.1-0.1-0.20.2-0.40.90.5-0.70.60.60.6
Fecal boli incidents, locomotor time 10.10.10.5-0.3-0.40.5-0.70.40.00.40.2-0.40.1-0.2-0.2-0.2
Change in fecal boli incidents, locomotor task1.61.73.91.71.7-1.72.0-1.71.5-1.40.50.90.20.50.50.5
Time >=10cm from walls, locomotor time 10.40.51.10.91.0-0.91.1-0.81.0-0.40.40.10.9-0.5-0.4-0.5
Bouts of movement, locomotor time 12.43.16.60.70.4-1.00.7-1.10.5-1.72.12.2-2.62.52.52.5
Total resting periods, locomotor time 12.02.34.20.70.5-1.00.7-1.10.8-1.51.81.9-2.02.02.02.0
Rest time, locomotor task time 10.50.71.30.40.4-0.60.4-0.70.6-0.91.11.2-1.11.11.01.0
Distance moved, locomotor task time 10.00.10.4-0.3-0.30.3-0.10.4-0.70.3-0.5-0.40.2-0.3-0.2-0.2
Vertical activity count, locomotor time 10.21.22.5-0.4-0.30.6-0.10.8-0.91.1-1.4-1.41.6-1.4-1.4-1.4
Time >=10cm from walls, locomotor time 20.20.61.90.30.7-0.20.4-0.10.30.3-0.5-0.71.4-1.2-1.1-1.2
Bouts of movement, locomotor time 20.51.64.6-0.2-0.3-0.10.0-0.3-0.4-0.91.11.3-2.12.02.02.0
Total resting periods, locomotor time 20.51.95.2-0.2-0.3-0.20.1-0.3-0.4-1.01.21.4-2.32.22.22.1
Rest time, locomotor task time 20.20.41.0-0.2-0.3-0.00.0-0.1-0.3-0.40.20.6-1.01.01.01.0
Distance moved, locomotor task time 20.00.00.10.10.1-0.10.0-0.1-0.1-0.20.20.3-0.40.20.20.2
Vertical activity count, locomotor time 20.71.72.6-1.4-1.21.4-1.31.5-1.61.5-1.2-1.20.7-1.2-1.2-1.2
Light reinforcement 10.20.92.4-1.0-1.40.9-1.50.7-1.10.30.50.2-1.21.00.60.6
Light reinforcement 20.92.14.4-2.0-2.11.8-2.01.8-2.11.4-0.9-0.8-0.4-0.0-0.3-0.4
Bone: marrow area0.92.16.6-0.10.70.10.60.5-0.71.0-1.3-1.52.6-2.0-2.3-2.2
Bone: maximum diameter0.10.10.5-0.10.10.10.10.3-0.70.3-0.2-0.40.5-0.2-0.6-0.4
Bone: maximum force0.91.74.0-1.0-0.51.0-0.31.2-1.51.4-2.0-1.71.3-1.8-1.2-1.1
Bone: maximum moment0.71.33.5-0.6-0.00.60.20.8-1.21.1-1.9-1.51.4-1.7-1.1-1.0
Mean time between licks in bursts0.31.63.1-1.1-0.91.2-1.01.1-0.61.5-1.3-1.61.3-1.7-1.4-1.3
Mean num. licks in bursts0.00.10.3-0.3-0.40.3-0.50.2-0.60.1-0.30.0-0.30.30.10.1
Cd content in liver0.60.61.8-0.6-0.90.4-0.40.4-1.0-0.10.60.6-1.31.01.01.0
Co content in liver1.31.54.2-0.0-0.1-0.30.2-0.4-0.5-0.91.11.3-2.11.72.02.0
Cu content in liver2.73.24.92.22.0-2.11.8-2.22.2-2.02.01.7-0.51.31.01.2
Fe content in liver0.30.30.70.60.8-0.50.6-0.50.8-0.1-0.3-0.20.7-0.6-0.3-0.5
K content in liver0.70.71.11.01.0-1.00.8-1.11.0-1.01.00.8-0.10.80.20.3
Mg content in liver0.50.51.00.91.0-0.90.7-0.91.0-0.70.70.50.30.4-0.2-0.1
Mn content in liver0.10.10.50.20.1-0.1-0.4-0.10.7-0.10.70.10.10.3-0.4-0.2
Na content in liver0.70.81.41.11.2-1.11.1-1.00.8-1.01.10.8-0.00.70.10.3
Rb content in liver0.20.20.50.30.2-0.30.0-0.40.6-0.50.70.5-0.60.50.70.6
Se content in liver0.20.21.10.40.3-0.3-0.1-0.30.6-0.41.10.5-0.30.60.00.1
Sr content in liver0.30.30.6-0.10.10.2-0.20.20.40.5-0.7-0.50.7-0.8-0.6-0.6
Zn content in liver2.63.14.92.11.9-2.11.9-2.12.0-2.02.21.7-0.51.41.00.9
Bone: minimum diameter3.46.612.2-1.5-0.81.7-1.12.0-1.72.7-2.9-3.33.4-3.5-3.4-3.2
Time in familiar zone, hab. session 11.41.53.30.70.9-1.01.2-1.00.3-1.30.81.5-1.41.51.61.8
Time in novel zone, hab. session 10.10.10.3-0.1-0.40.3-0.50.20.30.4-0.0-0.50.3-0.5-0.2-0.5
Total zone transitions, hab. session 10.91.32.0-1.3-1.31.4-1.41.3-0.81.4-1.1-1.30.5-1.1-0.8-0.8
Total locomotion distance, hab. session 10.91.32.3-0.8-0.60.9-0.90.9-0.21.3-0.9-1.41.4-1.5-1.5-1.5
Locomotion velocity, hab. session 11.42.03.0-1.2-1.01.3-1.31.3-0.61.6-1.2-1.71.5-1.7-1.7-1.7
Time in familiar zone, hab. session 23.54.06.41.51.3-1.81.6-1.91.4-2.22.02.4-2.12.32.42.5
Time in novel zone, hab. session 21.82.03.8-0.8-0.71.1-0.91.2-0.91.5-1.5-1.71.7-1.7-1.8-2.0
Total zone transitions, hab. session 20.20.30.8-0.5-0.60.5-0.80.30.30.10.30.2-0.90.40.70.7
Total locomotion distance, hab. session 20.20.30.5-0.5-0.60.6-0.70.60.00.7-0.4-0.60.4-0.6-0.5-0.5
Locomotion velocity, hab. session 20.10.20.3-0.4-0.40.5-0.60.40.10.5-0.3-0.50.3-0.5-0.5-0.4
Novel to familiar place preference ratio0.20.30.6-0.2-0.10.3-0.10.4-0.40.5-0.8-0.60.6-0.8-0.5-0.8
Novelty place preference0.10.10.40.00.10.10.10.2-0.30.3-0.6-0.40.3-0.5-0.2-0.5
Time in novel zone, NPP test0.00.10.3-0.0-0.00.10.10.2-0.50.1-0.6-0.2-0.0-0.20.2-0.1
Total zone transitions, NPP test0.30.51.4-1.1-1.01.0-1.20.8-0.40.7-0.2-0.3-0.4-0.0-0.10.1
Total locomotion distance, NPP test0.50.71.1-0.8-0.80.9-1.00.9-0.21.1-0.7-1.00.7-1.0-0.8-0.8
Locomotion velocity, NPP test0.40.61.3-0.5-0.50.7-0.80.60.20.9-0.5-1.01.0-1.1-1.0-0.9
Intraocular pressure1.93.14.6-2.1-1.72.0-1.62.0-2.12.0-2.1-1.80.8-1.6-1.2-1.2
Delta distance traveled before/after self-admin1.51.63.61.81.9-1.71.6-1.51.6-1.21.21.00.4-0.10.1-0.0
Delta ambulatory time before/after self-admin1.11.94.22.01.9-1.81.6-1.72.1-1.31.41.00.4-0.00.10.0
Parametrial fat weight0.10.30.5-0.4-0.30.4-0.30.4-0.30.6-0.6-0.60.6-0.7-0.6-0.6
Pavlov. Cond. lever latency0.91.12.50.80.8-0.91.0-1.00.5-1.10.71.1-1.11.01.41.6
Pavlov. Cond. magazine entry latency0.50.71.1-0.7-0.60.8-0.80.9-0.61.0-0.5-0.90.8-1.0-1.0-1.0
Pavlov. Cond. change in total contacts2.83.04.1-1.8-1.71.9-1.92.0-1.72.0-1.7-1.71.1-1.5-1.6-1.8
Pavlov. Cond. index score0.81.01.5-1.0-1.01.1-1.21.1-0.81.1-0.6-0.90.7-0.7-1.1-1.2
Pavlov. Cond. latency score0.60.81.3-0.9-1.01.0-1.11.1-0.71.0-0.5-0.80.6-0.6-1.0-1.1
Pavlov. Cond. lever contacts1.51.84.3-0.9-0.81.1-1.11.2-0.61.4-1.0-1.41.6-1.5-1.9-2.1
Pavlov. Cond. magazine entry number0.70.81.51.11.1-1.11.2-1.20.9-1.10.50.8-0.30.60.70.8
Pavlov. Cond. intertrial magazine entries0.40.41.50.80.9-0.80.6-0.81.2-0.50.60.10.6-0.1-0.4-0.3
Pavlov. Cond. lever-magazine prob. diff.0.70.91.4-0.9-1.01.0-1.21.1-0.71.1-0.6-0.90.7-0.7-1.0-1.2
Pavlov. Cond. response bias1.21.52.6-1.1-1.01.2-1.21.4-0.81.5-1.0-1.31.2-1.3-1.5-1.6
Pavlov. Cond. lever latency0.50.71.8-1.1-1.31.2-1.31.1-0.50.8-0.2-0.3-0.60.10.10.1
Pavlov. Cond. magazine entry latency0.00.00.1-0.1-0.10.1-0.00.2-0.30.2-0.2-0.30.3-0.3-0.2-0.2
Pavlov. Cond. change in total contacts0.61.64.2-0.30.20.4-0.00.5-0.41.0-1.3-1.52.0-2.0-1.8-1.9
Pavlov. Cond. index score0.40.61.6-0.00.30.00.30.1-0.40.5-0.9-0.91.3-1.2-1.0-1.0
Pavlov. Cond. latency score0.20.41.10.20.5-0.20.6-0.2-0.20.2-0.7-0.61.1-1.0-0.7-0.7
Pavlov. Cond. lever contacts0.30.41.10.71.1-0.81.0-0.80.2-0.5-0.10.00.8-0.3-0.5-0.4
Pavlov. Cond. magazine entry number0.20.30.50.40.2-0.40.2-0.40.6-0.50.50.7-0.70.70.70.7
Pavlov. Cond. intertrial magazine entries0.20.50.8-0.6-0.40.7-0.50.7-0.20.9-0.7-0.80.7-0.9-0.7-0.8
Pavlov. Cond. lever-magazine prob. diff.0.30.41.20.10.4-0.10.4-0.0-0.30.3-0.7-0.71.1-1.1-0.8-0.8
Pavlov. Cond. response bias0.40.51.70.20.5-0.20.5-0.1-0.30.2-0.7-0.71.3-1.0-1.0-1.0
Time in closed arm before self-admin0.71.22.41.21.0-1.20.9-1.21.2-1.21.61.2-0.71.00.80.8
Time in closed arm after self-admin1.41.63.40.60.7-0.90.8-0.80.1-1.31.21.8-1.81.71.71.5
Time in open arm before self-admin0.50.61.9-0.4-0.10.4-0.10.5-0.40.7-1.4-1.01.1-1.1-0.8-0.9
Time in open arm after self-admin1.01.13.0-0.9-0.70.9-0.51.1-1.31.0-1.7-1.41.0-0.8-0.9-0.8
Bone: periosteal estimation1.63.87.8-1.0-0.11.0-0.21.4-1.71.8-2.3-2.42.8-2.6-2.7-2.5
Bone: periosteal perimeter0.20.41.1-0.00.40.00.40.3-0.50.4-0.6-0.71.0-0.9-0.9-0.7
Bone: post-yield work1.52.76.22.12.3-2.12.5-2.01.4-1.80.91.2-0.30.51.21.2
Progressive ratio test 1 active lever presses1.01.84.01.81.5-1.61.3-1.72.0-1.51.41.1-0.30.70.80.7
Progressive ratio test 1 breakpoint1.01.84.11.81.5-1.61.3-1.72.0-1.51.41.1-0.20.70.70.7
Progressive ratio test 1 inactive lever presses0.00.00.10.20.00.00.0-0.00.20.1-0.4-0.30.3-0.3-0.2-0.2
Progressive ratio test 2 active lever presses1.92.76.42.22.5-2.12.5-2.02.1-1.30.50.41.4-0.5-0.4-0.4
Progressive ratio test 2 breakpoint2.02.66.02.22.4-2.12.5-1.92.0-1.30.50.41.4-0.5-0.4-0.4
Progressive ratio test 2 inactive lever presses0.20.71.91.31.2-1.11.4-1.00.8-0.90.20.40.40.10.20.2
Incentive Sensitization - Responses0.61.84.91.21.7-1.21.7-1.01.2-0.2-0.4-0.62.2-1.6-1.4-1.4
Incentive Sensitization - Breakpoint0.81.74.51.31.8-1.31.7-1.01.2-0.3-0.4-0.52.1-1.5-1.3-1.3
Sum of active levers in priming session hrs 5-60.40.41.30.50.7-0.50.7-0.50.8-0.00.3-0.41.1-0.8-0.8-0.7
Progressive ratio0.82.44.31.10.7-1.31.4-1.20.3-1.71.02.0-1.92.02.12.0
Food seeking constrained by brief footshock3.94.96.6-2.3-2.02.4-2.12.5-2.22.6-2.4-2.41.5-2.1-2.0-2.0
Seeking ratio, punishment vs. effort2.45.47.9-2.2-1.72.3-2.32.3-1.42.7-2.1-2.82.3-2.6-2.6-2.6
Retroperitoneal fat weight0.10.50.8-0.9-0.80.8-0.80.8-0.30.8-0.6-0.70.3-0.6-0.6-0.7
Reaction time number correct0.20.82.40.20.7-0.20.6-0.00.00.4-0.6-1.01.5-1.4-1.3-1.3
Reaction time mean minus median0.31.94.4-1.5-2.11.6-1.91.1-0.70.60.60.1-2.10.71.61.5
Reaction time mean minus median AUC0.32.15.9-1.8-2.42.0-2.31.6-1.11.10.2-0.4-1.50.11.00.9
Reaction time num false alarms0.81.34.50.81.2-0.61.0-0.40.60.2-0.5-0.82.1-1.5-1.6-1.6
Reaction time num false alarms AUC0.51.24.01.01.3-0.81.0-0.60.90.0-0.3-0.72.0-1.3-1.5-1.5
Reaction time trials correct on left0.20.82.40.20.7-0.20.6-0.00.00.4-0.6-1.01.5-1.4-1.3-1.3
Reaction time trials on left0.20.82.40.20.6-0.10.50.1-0.00.5-0.6-1.01.5-1.4-1.3-1.3
Reaction time mean0.61.43.8-1.5-1.91.7-1.91.5-0.81.3-0.3-0.8-0.4-0.6-0.0-0.1
Reaction time mean AUC0.71.64.1-1.5-2.01.8-2.01.6-0.91.5-0.4-1.0-0.2-0.8-0.2-0.3
Median of all reaction times1.01.62.8-1.3-1.71.6-1.71.5-0.91.5-0.8-1.30.5-1.2-0.8-0.9
Reaction time omissions1.93.19.3-2.3-2.82.5-3.12.0-1.21.8-0.5-1.2-0.9-0.30.0-0.0
Reaction time false alarm rate0.10.20.40.60.6-0.50.5-0.40.5-0.30.20.20.5-0.1-0.2-0.3
Reaction time premature initiation rate1.82.74.21.81.4-1.81.6-1.81.3-1.92.11.9-1.11.61.41.4
Reaction time premature initiations0.61.82.81.71.6-1.71.7-1.61.1-1.51.61.3-0.30.80.70.7
Std. dev. reaction times0.41.33.1-1.1-1.81.3-1.60.9-0.50.50.60.1-1.70.51.41.3
Reaction time trials completed0.20.82.40.20.6-0.10.50.1-0.00.5-0.6-1.01.5-1.4-1.3-1.3
Reaction time trials AUC0.30.92.60.00.50.00.30.2-0.20.6-0.7-1.21.6-1.5-1.4-1.4
Run reversals in cocaine runway, females0.30.30.6-0.8-0.80.6-0.60.7-0.80.5-0.5-0.40.00.0-0.3-0.3
Run reversals in cocaine runway, males1.82.03.1-1.7-1.71.8-1.71.7-1.51.6-1.1-1.40.6-0.9-1.0-1.0
Latency to leave start box in cocaine runway0.50.71.51.01.1-1.01.0-1.11.2-0.90.80.7-0.10.30.30.3
Latency to leave start box in cocaine runway, F1.92.34.32.02.1-2.02.0-1.92.1-1.71.11.20.10.50.50.5
Latency to leave start box in cocaine runway, M1.31.33.0-1.6-1.61.5-1.71.4-1.21.2-0.6-0.8-0.2-0.4-0.4-0.4
Std. dev. time between licks in bursts0.20.41.2-0.20.10.20.10.2-0.30.5-0.7-0.71.1-0.9-1.0-1.0
Total sessions with >9 infusions1.82.23.51.91.5-1.71.6-1.81.8-1.71.51.3-0.61.21.21.1
Short access day 1 total inactive lever presses1.42.84.91.51.1-1.51.2-1.71.5-1.92.21.9-1.51.71.81.8
Short access day 10 total inactive lever presses0.10.51.7-0.4-0.30.1-0.10.1-0.6-0.30.60.9-1.30.81.01.0
Short access day 1 total infusions1.63.34.42.01.7-2.01.8-2.12.0-2.12.11.8-1.01.51.61.5
Short access day 10 total infusions1.42.35.62.21.9-1.81.7-1.92.4-1.61.20.80.20.60.70.6
Short access total infusions1.52.14.31.91.5-1.71.5-1.82.1-1.61.51.1-0.30.80.90.9
Short access day 1 locomotion0.30.40.70.60.4-0.60.6-0.60.1-0.80.60.7-0.60.80.80.8
Short access day 10 total locomotion0.00.20.4-0.3-0.70.5-0.60.4-0.30.2-0.2-0.2-0.40.40.30.3
Short access total locomotion0.20.20.60.70.6-0.60.7-0.60.3-0.60.30.4-0.10.40.30.3
One hour access (0.3 mA shock)2.73.27.92.62.8-2.32.4-2.22.5-1.50.70.71.3-0.4-0.4-0.4
Compulsive drug intake0.20.31.0-0.9-0.60.7-0.60.7-1.00.5-0.5-0.1-0.40.00.10.0
One hour access (shock baseline)1.94.910.63.33.2-2.82.9-2.73.2-1.81.30.71.6-0.5-0.4-0.4
Social response proportion0.20.30.9-0.5-0.50.4-0.40.3-0.80.0-0.30.1-0.90.40.70.7
Social responses0.50.61.7-0.8-1.00.7-0.60.6-1.30.1-0.60.1-1.20.70.80.9
Social time0.00.10.20.1-0.30.2-0.40.00.20.2-0.0-0.40.1-0.4-0.1-0.1
Soleus weight0.82.45.8-1.9-1.81.9-1.71.9-2.41.6-1.9-1.30.1-0.8-0.6-0.5
Bone: stiffness0.30.61.4-0.8-0.50.8-0.30.8-1.10.8-1.2-0.90.4-0.8-0.4-0.2
Tibialis anterior weight7.726.641.5-6.1-5.65.9-5.56.2-6.45.7-6.0-4.71.9-3.2-3.7-3.6
Time to tail flick, vehicle, before self-admin0.20.30.50.40.6-0.50.4-0.40.7-0.00.0-0.10.7-0.6-0.6-0.7
Time to tail flick, vehicle, after self-admin0.91.94.51.82.0-1.82.1-1.71.7-1.40.70.80.50.20.20.1
Time to tail flick, test, before self-admin0.40.41.20.20.2-0.30.1-0.30.1-0.60.40.7-1.01.11.11.0
Time to tail flick, test, after self-admin1.11.12.01.41.1-1.31.2-1.31.2-1.20.80.8-0.30.90.80.9
Delta time to tail flick, vehicle, before/after SA1.71.83.61.91.7-1.61.8-1.71.7-1.41.30.90.20.50.50.4
Delta time to tail flick, test, before/after SA0.00.00.10.1-0.20.00.1-0.0-0.2-0.10.0-0.0-0.00.20.10.3
Tibia length0.82.14.91.72.0-1.82.2-1.71.0-1.60.81.3-0.40.81.01.1
Ambulatory time before self-admin0.31.03.5-1.3-1.11.1-0.71.3-1.90.9-1.5-0.70.0-0.1-0.2-0.2
Ambulatory time after self-admin0.10.10.40.50.6-0.40.6-0.30.2-0.2-0.00.10.4-0.3-0.2-0.3
Bone: tissue strength2.32.44.11.91.8-1.81.8-1.82.0-1.71.51.4-0.50.91.01.1
Total heroin consumption0.50.62.10.10.10.10.20.20.10.5-0.9-1.11.4-1.2-1.0-1.0
Bone: trabecular number0.20.40.90.90.9-0.80.9-0.70.8-0.50.60.20.6-0.1-0.4-0.3
Bone: trabecular spacing0.40.51.6-1.0-1.20.9-1.30.7-0.90.40.2-0.0-0.60.5-0.00.0
Bone: trabecular thickness0.60.81.91.01.1-0.91.4-0.70.5-0.2-0.4-0.41.4-1.1-0.7-0.7
Bone: trabecular tissue density1.22.15.4-1.8-2.31.8-2.11.4-1.60.9-0.5-0.3-1.60.41.11.0
Water consumed over 24 hours0.10.20.6-0.5-0.50.4-0.20.6-0.70.4-0.4-0.20.1-0.1-0.3-0.2
Number of responses in last shaping day0.30.40.90.80.7-0.80.9-0.80.2-0.80.50.7-0.30.60.50.5