Hub : Genes

Adam10

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression Adam10 0.01 0.01 7.3e-03 0.01 0.01 0.01 0.01 2.3e-02 1.5e-02 1.3e-02 2.3e-02
2 PL gene expression Adam10 0.05 0.06 8.2e-05 0.04 0.04 0.04 0.04 2.4e-05 4.1e-05 2.3e-05 2.5e-05
3 Brain mRNA stability Adam10 0.35 0.2 4.7e-13 0.14 0.13 0.13 0.14 3.5e-13 2.1e-12 8.5e-12 5.4e-13
4 Brain gene expression Adam10 0.19 0.13 0.0e+00 0.2 0.21 0.21 0.21 2.2e-18 2.4e-19 3.1e-19 4.1e-19
5 PL mRNA stability Adam10 0.17 0.12 1.8e-14 0.13 0.14 0.13 0.13 6.8e-14 1.7e-14 3.7e-14 3.4e-14
6 OFC mRNA stability Adam10 0.18 0.15 3.3e-03 0.09 0.09 0.09 0.1 3.6e-03 3.9e-03 3.2e-03 2.6e-03
7 IL mRNA stability Adam10 0.21 0.17 7.8e-04 0.1 0.08 0.1 0.08 1.9e-03 5.8e-03 2.3e-03 5.6e-03
8 Liver gene expression Adam10 0.02 0.02 7.8e-03 0.01 0.01 0.01 0 4.4e-02 5.3e-02 5.6e-02 7.5e-02
9 Adipose mRNA stability Adam10 0.1 0.07 3.6e-12 0.09 0.09 0.09 0.09 1.3e-10 1.6e-10 1.8e-10 1.6e-10
10 pVTA gene expression Adam10 0.07 0.09 3.8e-03 0.03 0.03 0.03 0.03 2.2e-03 3.6e-03 2.7e-03 3.3e-03
11 IL gene expression Adam10 0.35 0.23 5.3e-06 0.17 0.18 0.18 0.18 7.2e-05 5.2e-05 5.2e-05 3.9e-05
12 BLA mRNA stability Adam10 0.14 0.12 1.6e-06 0.09 0.09 0.1 0.1 1.9e-05 2.2e-05 5.7e-06 9.5e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.50.91.31.00.7-0.90.9-0.8-0.9-0.9-1.11.10.90.8-1.0
Area under the delay curve0.00.00.1-0.20.4-0.20.1-0.3-0.1-0.10.3-0.30.20.20.2
BMI with tail7.024.026.7-5.0-4.95.0-4.94.74.74.75.2-5.0-4.9-4.85.0
BMI without tail2.57.79.3-2.6-2.42.8-2.92.72.82.83.1-3.0-2.7-2.72.9
Body weight4.821.123.4-4.8-4.84.8-4.64.54.44.44.7-4.6-4.6-4.54.4
Weight adjusted by age4.46.67.8-2.0-2.62.4-2.72.62.82.82.6-2.4-2.7-2.72.4
Bone surface0.00.10.2-0.2-0.50.3-0.30.40.20.20.10.1-0.3-0.40.1
Bone volume0.00.00.10.1-0.20.10.00.1-0.0-0.0-0.20.3-0.0-0.1-0.1
Breakpoint value in progressive ratio session0.70.81.4-0.6-0.60.9-1.00.90.90.81.0-1.2-1.0-0.91.1
Number of licking bursts1.52.43.81.91.7-1.51.5-1.4-1.5-1.5-1.61.51.51.5-1.4
Context. condit. distance diff. score0.91.11.60.60.9-1.01.1-1.1-1.1-1.1-0.90.91.31.2-1.0
Locomotion velocity, session 11.51.63.1-0.9-1.71.3-1.21.51.51.50.6-0.7-1.4-1.40.9
Locomotion distance, session 10.20.30.80.70.0-0.40.5-0.3-0.3-0.3-0.90.70.40.4-0.7
Locomotion velocity, session 20.20.30.7-0.1-0.90.5-0.40.60.50.50.2-0.3-0.7-0.50.4
Locomotion distance, session 20.20.20.60.2-0.80.3-0.40.60.60.6-0.1-0.3-0.6-0.50.3
Locomotion velocity, session 30.00.00.10.0-0.20.00.10.10.20.2-0.40.4-0.2-0.0-0.3
Locomotion distance, session 31.81.92.61.41.3-1.31.5-1.3-1.3-1.3-1.61.61.31.3-1.5
Stereotopy head waving bouts, day 30.70.81.8-1.3-0.70.9-0.90.80.70.71.2-1.0-0.7-0.80.8
Stereotopy head waving duration, day 30.81.02.1-1.5-0.80.9-1.00.80.70.71.3-1.2-0.8-0.91.0
Locomotion velocity, session 71.61.82.91.61.1-1.21.4-1.2-1.2-1.2-1.71.51.21.2-1.4
Locomotion distance, session 71.62.13.21.81.3-1.31.5-1.3-1.4-1.4-1.71.21.51.4-1.3
Stereotopy head waving bouts, day 71.31.42.7-1.6-0.91.1-1.21.00.90.91.6-1.3-1.1-1.01.3
Stereotopy head waving duration, day 71.01.22.7-1.6-0.80.9-1.10.80.80.81.6-1.2-1.0-0.91.1
Locomotion velocity, session 80.40.51.3-0.4-1.10.7-0.60.90.80.80.1-0.3-0.8-0.70.4
Locomotion distance, session 80.50.81.40.90.5-0.90.9-0.8-0.8-0.8-1.20.90.90.9-0.9
Degree of sensitization distance0.20.20.40.60.5-0.50.4-0.5-0.5-0.5-0.40.10.60.5-0.3
Degree of sensitization stereotypy0.70.71.3-1.1-0.60.7-0.80.70.70.71.2-0.9-0.9-0.70.9
Conditioned locomotion0.10.10.40.40.3-0.60.3-0.4-0.2-0.2-0.30.30.30.4-0.3
Cocaine response after cond. corrected3.54.34.7-1.9-2.12.0-2.12.12.22.22.1-2.0-2.1-2.12.1
Cocaine response after cond. not corrected2.32.73.2-1.4-1.81.5-1.61.71.81.81.5-1.6-1.7-1.71.6
Cocaine response before conditioning0.91.11.40.90.9-1.01.1-1.0-1.1-1.1-1.21.10.91.0-1.2
Saline control response0.10.10.4-0.60.0-0.30.1-0.3-0.2-0.20.2-0.00.20.2-0.2
Bone: connectivity density1.01.52.01.31.1-1.41.2-1.1-1.1-1.1-1.31.41.11.2-1.3
Bone: cortical apparent density1.21.62.01.31.4-1.31.3-1.3-1.2-1.2-1.21.31.31.3-1.2
Bone: cortical area0.10.10.30.0-0.00.00.3-0.1-0.1-0.1-0.50.60.10.1-0.5
Bone: cortical porosity1.11.21.61.31.1-1.01.1-1.1-1.1-1.1-1.11.10.91.0-1.1
Bone: cortical porosity1.61.82.41.61.3-1.31.3-1.3-1.4-1.4-1.31.31.21.3-1.3
Bone: cortical thickness1.62.63.41.61.5-1.51.7-1.5-1.5-1.5-1.81.81.51.5-1.8
Bone: cortical thickness0.60.71.10.80.8-0.80.9-0.7-0.7-0.7-1.01.10.70.7-1.0
Bone: cortical tissue density1.11.51.91.21.4-1.31.2-1.3-1.1-1.1-1.21.21.21.2-1.2
Condit. Reinf. active minus inactive responses0.00.00.1-0.2-0.20.00.10.0-0.0-0.0-0.20.2-0.0-0.0-0.2
Condit. Reinf. active-inactive response ratio0.40.40.60.50.7-0.70.7-0.7-0.6-0.6-0.70.60.60.7-0.8
Condit. Reinf. active responses0.40.51.0-1.0-1.00.8-0.60.70.70.70.5-0.5-0.8-0.80.5
Condit. Reinf. inactive responses1.21.42.1-1.3-1.41.2-1.11.21.31.31.0-1.0-1.3-1.20.9
Incentive salience index mean0.00.10.2-0.3-0.40.3-0.00.20.20.2-0.20.2-0.2-0.2-0.3
Condit. Reinf. lever presses0.00.10.20.0-0.20.20.10.10.10.1-0.40.3-0.1-0.1-0.3
Condit. Reinf. active minus inactive responses3.34.25.4-2.1-2.32.3-2.12.22.12.11.9-1.6-2.1-2.21.6
Condit. Reinf. active-inactive response ratio0.91.11.3-1.1-1.01.1-1.11.11.01.01.2-0.8-1.0-1.10.8
Condit. Reinf. active responses1.92.73.6-1.7-1.91.9-1.61.81.81.81.3-1.0-1.7-1.81.1
Condit. Reinf. inactive responses0.10.20.4-0.2-0.60.5-0.10.50.40.4-0.40.3-0.4-0.4-0.2
Condit. Reinf. lever presses0.50.72.10.70.5-0.50.9-0.6-0.6-0.6-1.11.50.70.6-1.3
Condit. Reinf. lever reinforcers received1.31.92.7-1.5-1.71.6-1.31.51.51.51.0-0.7-1.4-1.50.7
Conditioned reinforcement - actives0.10.20.8-0.4-0.00.2-0.3-0.00.30.30.9-0.9-0.1-0.00.8
Conditioned reinforcement - inactives0.10.10.40.40.6-0.00.3-0.4-0.2-0.2-0.1-0.10.30.50.0
Conditioned locomotion0.20.30.60.30.7-0.70.5-0.8-0.5-0.5-0.00.00.60.6-0.2
Patch foraging indifference point 0 sec0.50.92.2-1.0-1.11.0-0.71.01.51.50.3-0.2-0.9-0.80.2
Patch foraging indifference point AUC0.10.21.0-0.1-1.00.6-0.30.5-0.0-0.00.0-0.0-0.6-0.50.1
Delay disc. indifference point, 0s delay0.30.30.70.30.8-0.60.6-0.7-0.4-0.4-0.30.40.50.7-0.5
Delay disc. indifference point, 16s delay0.20.30.60.20.8-0.60.5-0.7-0.6-0.60.0-0.20.60.60.0
Delay disc. indifference point, 2s delay0.10.10.50.10.7-0.40.2-0.4-0.2-0.20.2-0.10.30.20.2
Delay disc. indifference point, 24s delay0.20.30.5-0.00.7-0.60.5-0.7-0.6-0.6-0.30.20.50.5-0.3
Delay disc. indifference point, 4s delay0.10.20.30.20.5-0.50.4-0.6-0.3-0.3-0.00.10.50.5-0.2
Delay disc. indifference point, 8s delay0.10.10.2-0.20.00.1-0.20.10.10.10.3-0.4-0.1-0.10.5
Indifference point function ln k0.20.40.6-0.6-0.10.4-0.70.50.80.80.7-0.8-0.6-0.50.7
Indifference point function log k0.20.40.6-0.6-0.10.4-0.70.50.80.80.7-0.8-0.6-0.50.7
Patch foraging total patch changes 0 sec0.51.02.5-0.9-1.11.1-0.81.11.61.60.4-0.3-1.1-0.90.3
Patch foraging total patch changes 12 sec0.10.10.4-0.5-0.60.4-0.10.30.40.4-0.10.4-0.3-0.2-0.4
Patch foraging total patch changes 18 sec0.20.30.5-0.7-0.70.7-0.50.60.60.60.3-0.2-0.7-0.50.3
Patch foraging total patch changes 24 sec0.30.51.2-0.3-1.00.7-0.50.91.11.1-0.10.2-0.9-0.7-0.1
Patch foraging total patch changes 6 sec0.71.12.4-0.7-1.61.2-0.91.11.21.20.5-0.6-1.0-1.00.6
Patch foraging time to switch 0 sec1.42.84.71.62.2-1.81.6-1.9-1.6-1.6-1.31.21.91.9-1.2
Patch foraging water rate 0 sec2.04.35.4-1.8-2.32.1-2.12.22.32.31.7-1.8-2.3-2.21.6
Patch foraging water rate 12 sec3.26.88.5-2.3-2.82.9-2.72.92.72.72.1-2.1-2.8-2.92.1
Patch foraging water rate 18 sec0.40.61.4-0.6-0.70.7-0.80.91.21.20.4-0.5-0.8-0.80.4
Patch foraging water rate 24 sec0.40.51.1-0.4-0.61.0-0.70.90.90.90.3-0.5-0.7-0.90.6
Patch foraging water rate 6 sec1.62.33.3-1.8-1.61.4-1.51.51.61.61.3-1.3-1.6-1.51.2
Seeking ratio, delayed vs. immediate footshock0.50.71.0-0.7-0.61.0-0.80.90.90.90.7-0.8-0.8-0.80.7
Distance traveled before self-admin0.20.20.60.10.7-0.20.1-0.6-0.5-0.50.6-0.80.50.30.6
Distance traveled after self-admin1.01.21.8-1.2-0.60.9-1.10.91.31.21.2-1.3-0.9-1.01.3
Extensor digitorum longus weight8.232.335.0-5.5-5.25.6-5.85.75.85.85.9-5.7-5.7-5.65.7
Bone: elastic displacement0.30.30.6-0.5-0.50.6-0.60.50.30.30.8-0.7-0.6-0.60.7
Bone: elastic work0.00.00.10.0-0.20.2-0.10.20.10.10.0-0.0-0.2-0.20.1
Bone: endosteal estimation2.35.16.6-2.6-2.42.3-2.22.32.22.22.1-2.0-2.3-2.22.0
Bone: endosteal perimeter3.57.48.3-2.9-2.92.8-2.72.82.72.72.6-2.5-2.8-2.72.5
Epididymis fat weight0.00.00.1-0.00.30.1-0.1-0.0-0.1-0.10.20.0-0.00.00.1
Delta time in closed arm before/after self-admin1.21.22.11.51.0-1.01.0-1.0-0.9-0.9-1.21.30.91.1-1.1
Delta time in open arm before/after self-admin0.10.10.20.40.1-0.40.4-0.3-0.3-0.3-0.50.50.20.3-0.5
Diff in mean of infusions in LGA sessions1.11.31.8-1.3-1.31.1-1.11.11.11.11.2-1.2-1.2-1.11.1
Delay discount exponential model param0.10.10.20.3-0.30.10.00.2-0.00.0-0.40.4-0.1-0.1-0.3
Extinction: sum of active levers before priming0.40.40.7-0.9-0.70.3-0.70.60.70.70.5-0.7-0.6-0.50.5
Active lever presses in extinction session 60.50.50.9-0.7-0.50.5-0.70.60.50.50.8-0.8-0.8-0.60.9
Bone: final force0.30.40.9-0.6-0.90.9-0.60.80.80.80.2-0.2-0.6-0.70.3
Bone: final moment0.10.10.3-0.2-0.50.5-0.10.40.40.4-0.20.3-0.2-0.3-0.1
Food consumed during 24 hour testing period0.71.01.9-1.4-1.00.9-1.00.80.90.91.2-1.1-0.8-0.81.0
Glucose1.01.62.3-1.2-1.51.3-1.21.31.31.31.1-1.1-1.3-1.31.2
Heart weight1.01.63.1-1.7-1.01.0-1.20.91.11.11.8-1.6-0.8-1.11.5
Delay discount hyperbolic model param0.10.10.20.2-0.40.3-0.10.30.10.1-0.30.3-0.2-0.2-0.2
Intermittent access intake day 1-15 change0.51.11.91.11.1-1.41.0-1.2-0.9-0.9-0.70.91.11.2-0.9
Intermittent access intake escalation0.30.71.30.91.0-1.20.8-0.9-0.5-0.5-0.70.90.70.9-0.8
Intermittent access intake escalation 20.00.00.3-0.00.3-0.50.0-0.30.10.10.3-0.20.10.20.2
Intermitt. access day 1 inactive lever presses1.03.84.72.11.8-1.82.0-1.9-1.8-1.8-1.92.12.01.8-2.2
Intermitt. access day 15 inactive lever presses0.10.10.5-0.7-0.2-0.0-0.2-0.10.00.00.7-0.5-0.10.10.4
Intermitt. access escalation Index0.40.51.8-1.3-0.60.7-0.60.60.60.60.7-0.9-0.6-0.40.5
Intermittent access day 1 total infusions0.60.91.21.01.1-0.91.0-1.0-1.1-1.1-0.90.71.01.0-0.7
Intermittent access day 15 total infusions1.31.92.71.41.6-1.51.4-1.5-1.1-1.1-1.21.31.31.5-1.3
Intermittent access terminal intake (last 3 days)0.60.81.41.21.1-1.10.9-1.0-0.7-0.7-0.60.71.01.0-0.6
Intermittent access total infusions0.30.40.70.80.8-0.70.6-0.7-0.5-0.5-0.50.40.70.7-0.4
Intermittent access day 1 locomotion2.32.93.31.61.8-1.71.8-1.8-1.8-1.8-1.61.71.81.7-1.6
Intermittent access day 15 total locomotion1.32.43.71.61.8-1.91.5-1.7-1.4-1.3-1.31.61.61.6-1.4
Intermittent access total locomotion0.10.10.30.10.5-0.40.1-0.30.00.00.20.20.20.2-0.1
Intermittent access standard deviation0.20.50.80.90.8-0.90.6-0.7-0.7-0.7-0.50.60.70.7-0.4
Left kidney weight1.67.79.8-2.8-2.52.7-2.82.62.72.73.1-2.9-2.6-2.73.0
Right kidney weight2.411.113.4-3.4-3.23.4-3.33.13.23.23.7-3.6-3.1-3.23.5
Cocaine induced anxiety0.10.10.3-0.20.6-0.40.3-0.5-0.5-0.5-0.10.10.50.3-0.2
Post-drug Anxiety2.42.63.01.41.7-1.71.6-1.7-1.7-1.7-1.51.51.71.6-1.5
Baseline Anxiety0.80.91.91.40.7-0.80.9-0.8-0.9-0.9-1.11.10.80.9-1.0
Tail length0.00.00.10.20.2-0.1-0.0-0.00.10.10.1-0.00.10.1-0.1
Length with tail0.62.63.4-1.6-1.91.7-1.61.71.61.61.4-1.4-1.6-1.71.3
Length without tail3.912.516.8-3.9-4.13.8-3.53.63.33.33.2-3.2-3.6-3.73.2
Times rat made contact with spout0.60.71.30.51.0-1.20.7-1.0-0.9-0.9-0.30.41.01.0-0.4
Lifetime Intake0.20.20.80.90.6-0.40.4-0.4-0.3-0.3-0.40.30.40.5-0.2
Liver weight, left3.86.38.1-2.3-2.92.6-2.62.72.52.52.3-2.2-2.5-2.72.2
Liver weight, right1.32.33.9-1.4-2.01.8-1.41.71.61.61.2-1.3-1.5-1.61.2
Locomotor activity6.39.812.6-3.5-3.02.9-3.23.03.13.13.3-3.3-3.0-3.03.1
Locomotor testing distance3.56.28.2-2.9-2.42.2-2.62.42.32.32.8-2.7-2.4-2.42.6
Locomotor testing rearing1.63.34.0-1.7-1.51.7-1.81.82.02.01.9-1.9-1.7-1.71.9
Locomotion in novel chamber0.20.30.70.30.4-0.60.5-0.5-0.2-0.2-0.50.80.50.5-0.9
Locomotion in novel chamber post-restriction0.50.91.30.90.8-1.01.0-1.1-0.9-0.9-0.80.81.21.1-0.8
Fecal boli incidents, locomotor time 10.10.20.5-0.60.1-0.20.3-0.4-0.7-0.7-0.00.20.50.3-0.2
Change in fecal boli incidents, locomotor task0.10.10.70.8-0.20.1-0.20.30.30.3-0.1-0.3-0.1-0.30.1
Time >=10cm from walls, locomotor time 10.20.21.5-1.2-0.30.3-0.40.30.10.10.5-0.4-0.2-0.30.5
Bouts of movement, locomotor time 10.10.10.3-0.2-0.20.3-0.30.40.60.60.40.2-0.5-0.2-0.0
Total resting periods, locomotor time 10.10.20.6-0.1-0.10.3-0.30.40.70.80.30.1-0.5-0.20.0
Rest time, locomotor task time 10.00.10.20.4-0.1-0.0-0.10.10.40.4-0.10.1-0.0-0.0-0.0
Distance moved, locomotor task time 10.10.10.30.1-0.0-0.30.3-0.3-0.6-0.6-0.30.20.20.3-0.3
Vertical activity count, locomotor time 10.10.20.30.30.4-0.50.4-0.6-0.4-0.4-0.20.20.50.5-0.3
Time >=10cm from walls, locomotor time 20.00.10.3-0.5-0.40.3-0.10.3-0.0-0.0-0.10.1-0.1-0.2-0.0
Bouts of movement, locomotor time 21.01.62.6-1.4-1.01.1-1.31.11.01.01.6-1.4-1.2-1.11.4
Total resting periods, locomotor time 21.01.72.8-1.3-0.91.1-1.41.21.21.21.7-1.5-1.2-1.11.6
Rest time, locomotor task time 20.20.20.40.50.6-0.50.5-0.4-0.3-0.3-0.50.60.50.5-0.5
Distance moved, locomotor task time 20.00.00.2-0.3-0.4-0.00.00.0-0.2-0.2-0.20.2-0.10.0-0.1
Vertical activity count, locomotor time 20.30.50.80.50.7-0.90.7-0.9-0.6-0.6-0.40.30.90.9-0.4
Light reinforcement 12.66.49.0-3.0-2.52.5-2.52.62.72.72.4-2.3-2.5-2.52.2
Light reinforcement 20.10.10.40.40.3-0.10.4-0.2-0.3-0.3-0.60.60.30.2-0.5
Bone: marrow area2.35.06.4-2.5-2.42.3-2.22.22.22.22.1-2.0-2.3-2.22.0
Bone: maximum diameter2.14.05.2-2.1-2.32.1-1.92.12.02.01.7-1.6-2.1-2.01.7
Bone: maximum force0.20.40.6-0.6-0.80.8-0.60.70.70.70.4-0.3-0.7-0.70.4
Bone: maximum moment0.00.10.2-0.3-0.40.4-0.20.30.30.3-0.00.1-0.3-0.30.0
Mean time between licks in bursts0.20.50.80.70.9-0.90.7-0.8-0.9-0.9-0.50.30.70.8-0.6
Mean num. licks in bursts0.61.02.1-1.4-0.90.7-1.00.70.80.81.3-1.1-0.8-0.81.1
Cd content in liver1.41.62.11.11.5-1.21.2-1.3-1.3-1.3-1.11.11.41.3-1.2
Co content in liver1.31.52.01.41.4-1.41.2-1.3-1.3-1.3-1.11.01.21.3-1.1
Cu content in liver0.00.00.00.2-0.1-0.0-0.00.10.20.2-0.10.1-0.2-0.10.0
Fe content in liver0.30.40.8-0.9-0.80.6-0.60.60.50.50.5-0.3-0.6-0.60.3
K content in liver2.01.92.8-1.3-1.41.2-1.41.41.41.41.3-1.1-1.7-1.41.2
Mg content in liver1.61.62.1-1.1-1.31.2-1.31.31.31.31.2-1.2-1.5-1.31.2
Mn content in liver0.00.00.00.10.2-0.20.1-0.2-0.2-0.2-0.20.10.10.2-0.1
Na content in liver8.49.010.7-3.0-3.33.1-3.03.13.03.02.7-2.7-3.1-3.12.7
Rb content in liver0.50.60.9-0.7-0.60.6-0.80.80.90.90.8-0.8-1.0-0.70.8
Se content in liver0.00.00.1-0.00.2-0.20.1-0.2-0.2-0.2-0.10.30.10.1-0.3
Sr content in liver0.00.00.10.10.1-0.10.2-0.1-0.3-0.3-0.20.20.20.2-0.2
Zn content in liver0.00.10.2-0.1-0.20.1-0.20.20.30.30.2-0.0-0.4-0.20.1
Bone: minimum diameter0.00.10.2-0.4-0.0-0.00.3-0.2-0.1-0.1-0.30.50.10.2-0.4
Time in familiar zone, hab. session 10.00.00.30.5-0.0-0.10.10.10.00.0-0.30.3-0.0-0.0-0.1
Time in novel zone, hab. session 10.10.10.1-0.20.1-0.20.2-0.3-0.3-0.30.00.00.30.3-0.1
Total zone transitions, hab. session 10.40.61.11.00.7-0.70.7-0.6-0.5-0.5-1.01.10.50.6-1.1
Total locomotion distance, hab. session 10.00.10.20.20.1-0.20.2-0.1-0.2-0.2-0.40.40.20.1-0.4
Locomotion velocity, hab. session 10.00.00.0-0.1-0.00.0-0.10.10.10.1-0.00.1-0.0-0.1-0.2
Time in familiar zone, hab. session 20.10.10.30.60.1-0.10.2-0.1-0.3-0.3-0.40.20.30.2-0.1
Time in novel zone, hab. session 20.00.00.1-0.30.1-0.20.1-0.2-0.1-0.1-0.00.20.00.2-0.2
Total zone transitions, hab. session 20.30.40.8-0.3-0.90.7-0.60.80.70.70.3-0.4-0.8-0.80.5
Total locomotion distance, hab. session 20.71.01.1-0.9-1.00.9-1.01.11.01.00.9-1.0-1.0-1.00.9
Locomotion velocity, hab. session 20.40.50.6-0.5-0.70.7-0.70.80.70.70.6-0.7-0.7-0.80.6
Novel to familiar place preference ratio0.91.01.3-1.0-1.01.1-1.00.91.01.01.1-1.0-1.0-1.01.1
Novelty place preference1.01.11.3-1.0-1.01.1-1.01.01.01.01.1-0.9-1.0-1.01.1
Time in novel zone, NPP test1.21.31.5-1.2-1.21.2-1.11.11.11.11.2-1.1-1.1-1.11.2
Total zone transitions, NPP test0.30.40.8-0.4-0.90.4-0.60.70.70.70.3-0.2-0.8-0.70.2
Total locomotion distance, NPP test0.60.91.2-0.8-1.00.9-0.91.01.11.10.8-0.7-1.0-1.00.7
Locomotion velocity, NPP test0.20.30.5-0.4-0.60.5-0.60.70.70.70.4-0.4-0.7-0.70.3
Intraocular pressure0.00.00.10.1-0.10.0-0.0-0.1-0.3-0.30.1-0.40.10.00.3
Delta distance traveled before/after self-admin1.51.62.8-1.2-1.41.2-1.21.51.71.70.7-0.7-1.4-1.40.8
Delta ambulatory time before/after self-admin0.60.71.3-0.9-1.00.8-0.81.01.11.10.3-0.3-0.9-0.90.3
Parametrial fat weight0.92.12.81.71.1-1.41.5-1.4-1.6-1.6-1.61.41.41.4-1.2
Pavlov. Cond. lever latency0.10.20.30.40.4-0.50.4-0.5-0.4-0.4-0.40.20.50.5-0.2
Pavlov. Cond. magazine entry latency0.60.71.41.10.6-0.70.9-0.7-0.7-0.7-1.21.10.70.7-1.0
Pavlov. Cond. change in total contacts0.00.00.1-0.20.0-0.0-0.0-0.10.00.00.30.2-0.20.0-0.1
Pavlov. Cond. index score0.40.50.90.80.6-0.50.7-0.6-0.6-0.6-0.91.00.50.6-0.9
Pavlov. Cond. latency score0.10.20.50.50.3-0.20.4-0.3-0.3-0.3-0.50.70.20.3-0.6
Pavlov. Cond. lever contacts0.00.00.00.0-0.10.2-0.10.20.20.2-0.00.1-0.2-0.2-0.1
Pavlov. Cond. magazine entry number0.81.01.4-1.1-0.90.8-1.10.91.01.01.2-1.2-0.9-0.91.2
Pavlov. Cond. intertrial magazine entries0.10.20.3-0.4-0.60.3-0.30.40.50.50.1-0.3-0.4-0.40.4
Pavlov. Cond. lever-magazine prob. diff.0.20.30.50.70.4-0.30.5-0.4-0.4-0.4-0.60.70.30.4-0.7
Pavlov. Cond. response bias0.30.40.60.80.5-0.40.6-0.5-0.5-0.5-0.70.80.40.5-0.7
Pavlov. Cond. lever latency0.20.31.2-0.4-0.10.3-0.50.30.20.20.9-1.1-0.3-0.31.0
Pavlov. Cond. magazine entry latency3.44.25.31.92.0-2.12.0-2.0-1.9-1.9-2.02.32.02.1-2.3
Pavlov. Cond. change in total contacts0.30.51.30.50.4-0.60.7-0.6-0.6-0.5-0.91.00.60.6-1.2
Pavlov. Cond. index score0.91.22.31.00.8-1.01.1-0.9-0.8-0.8-1.31.50.91.0-1.5
Pavlov. Cond. latency score0.50.71.60.70.6-0.80.8-0.7-0.6-0.6-1.01.20.70.8-1.2
Pavlov. Cond. lever contacts0.20.31.10.40.1-0.30.5-0.3-0.2-0.1-0.81.00.30.3-1.0
Pavlov. Cond. magazine entry number3.54.35.6-2.0-2.02.1-2.12.01.91.92.2-2.4-1.9-2.12.3
Pavlov. Cond. intertrial magazine entries1.01.52.3-1.5-1.41.4-1.21.20.90.91.1-1.2-1.0-1.21.2
Pavlov. Cond. lever-magazine prob. diff.1.01.42.51.20.9-1.11.2-1.0-0.9-0.9-1.41.61.01.1-1.5
Pavlov. Cond. response bias1.31.83.31.31.1-1.21.4-1.1-1.0-1.0-1.61.81.21.2-1.8
Time in closed arm before self-admin0.20.20.6-0.60.3-0.60.3-0.6-0.7-0.80.2-0.00.50.4-0.0
Time in closed arm after self-admin0.80.91.70.41.0-0.90.9-1.1-1.3-1.3-0.70.71.01.0-0.8
Time in open arm before self-admin0.60.71.1-0.2-0.61.1-0.80.81.01.00.7-1.0-0.7-0.60.9
Time in open arm after self-admin0.30.40.8-0.1-0.80.6-0.50.70.90.90.3-0.5-0.6-0.60.5
Bone: periosteal estimation1.22.53.6-1.9-1.81.7-1.51.61.61.61.3-1.2-1.7-1.61.3
Bone: periosteal perimeter2.03.44.2-2.0-2.02.0-1.81.91.91.91.6-1.5-1.9-1.81.6
Bone: post-yield work0.10.10.2-0.5-0.30.1-0.30.20.30.30.3-0.3-0.4-0.10.3
Progressive ratio test 1 active lever presses0.10.10.20.50.3-0.30.4-0.4-0.4-0.4-0.30.20.40.4-0.1
Progressive ratio test 1 breakpoint0.10.20.30.50.4-0.40.5-0.5-0.5-0.5-0.40.20.40.5-0.2
Progressive ratio test 1 inactive lever presses2.13.04.52.11.5-1.51.8-1.6-1.6-1.6-2.01.81.61.7-1.7
Progressive ratio test 2 active lever presses0.20.20.5-0.0-0.10.2-0.40.20.60.60.5-0.5-0.3-0.20.7
Progressive ratio test 2 breakpoint0.10.20.40.1-0.10.2-0.30.20.60.60.5-0.5-0.3-0.20.6
Progressive ratio test 2 inactive lever presses0.10.20.40.60.6-0.40.5-0.6-0.3-0.3-0.30.40.50.5-0.3
Incentive Sensitization - Responses0.20.20.6-0.2-0.00.2-0.50.20.70.70.7-0.6-0.2-0.30.7
Incentive Sensitization - Breakpoint0.10.10.4-0.00.10.1-0.30.10.60.60.6-0.4-0.1-0.10.6
Sum of active levers in priming session hrs 5-60.10.10.2-0.40.00.1-0.30.20.30.30.4-0.5-0.3-0.20.4
Progressive ratio1.01.63.71.11.9-1.31.2-1.5-1.4-1.4-0.50.81.31.3-0.6
Food seeking constrained by brief footshock0.20.20.4-0.5-0.40.5-0.50.50.20.20.4-0.4-0.6-0.50.5
Seeking ratio, punishment vs. effort3.95.69.4-2.3-3.12.5-2.42.72.42.41.7-1.9-2.6-2.51.7
Retroperitoneal fat weight0.00.20.50.1-0.1-0.30.4-0.3-0.4-0.4-0.50.70.30.3-0.6
Reaction time number correct1.01.93.0-1.1-1.31.3-1.51.31.31.31.4-1.7-1.4-1.41.7
Reaction time mean minus median0.00.10.40.5-0.20.30.20.1-0.1-0.1-0.30.70.0-0.1-0.6
Reaction time mean minus median AUC0.20.61.51.20.4-0.30.7-0.5-0.6-0.6-0.91.20.50.5-1.1
Reaction time num false alarms0.50.71.20.70.7-0.70.8-0.7-1.0-1.0-1.10.80.90.8-0.9
Reaction time num false alarms AUC0.20.30.60.30.2-0.30.5-0.3-0.7-0.7-0.80.60.50.4-0.6
Reaction time trials correct on left1.01.93.0-1.1-1.31.3-1.51.31.31.31.4-1.7-1.4-1.41.7
Reaction time trials on left1.12.13.2-1.1-1.31.3-1.51.41.41.41.4-1.7-1.5-1.41.8
Reaction time mean2.13.35.62.41.5-1.51.8-1.5-1.8-1.8-2.02.11.51.6-2.1
Reaction time mean AUC1.42.34.22.11.2-1.21.5-1.3-1.4-1.4-1.71.81.31.3-1.8
Median of all reaction times4.15.88.52.92.2-2.22.4-2.2-2.4-2.3-2.62.62.12.2-2.7
Reaction time omissions0.20.30.50.1-0.50.7-0.50.60.70.70.4-0.4-0.5-0.60.4
Reaction time false alarm rate1.21.62.30.91.0-1.11.3-1.1-1.3-1.3-1.51.51.31.2-1.5
Reaction time premature initiation rate1.62.22.8-0.8-1.61.6-1.61.71.41.41.3-1.5-1.5-1.61.6
Reaction time premature initiations2.03.64.6-1.1-2.02.0-2.02.11.81.81.7-2.1-1.9-2.02.1
Std. dev. reaction times0.61.12.61.60.7-0.61.0-0.8-1.0-1.0-1.21.40.80.7-1.3
Reaction time trials completed1.12.13.2-1.1-1.31.3-1.51.41.41.41.4-1.7-1.5-1.41.8
Reaction time trials AUC0.91.72.8-1.0-1.21.2-1.41.31.21.21.3-1.6-1.3-1.31.7
Run reversals in cocaine runway, females0.00.00.10.20.1-0.30.1-0.10.30.3-0.20.0-0.00.10.0
Run reversals in cocaine runway, males0.10.10.1-0.0-0.20.3-0.20.30.40.40.2-0.1-0.2-0.40.1
Latency to leave start box in cocaine runway2.32.63.9-1.9-1.51.6-1.61.41.51.51.8-2.0-1.2-1.51.9
Latency to leave start box in cocaine runway, F0.70.81.8-1.3-0.90.9-0.90.80.70.71.0-1.0-0.7-0.90.9
Latency to leave start box in cocaine runway, M5.55.27.1-2.2-2.22.1-2.22.02.32.32.5-2.6-1.9-2.02.7
Std. dev. time between licks in bursts0.50.71.0-0.8-1.01.0-0.81.01.01.00.5-0.4-1.0-0.90.4
Total sessions with >9 infusions0.20.21.01.00.3-0.10.4-0.3-0.1-0.1-0.60.40.30.4-0.3
Short access day 1 total inactive lever presses0.60.81.21.11.1-0.80.9-0.9-0.8-0.8-0.90.80.90.9-0.8
Short access day 10 total inactive lever presses0.61.52.00.71.1-1.31.3-1.4-1.4-1.4-1.01.21.21.2-1.3
Short access day 1 total infusions0.20.31.31.10.7-0.30.5-0.6-0.5-0.5-0.30.20.60.60.0
Short access day 10 total infusions1.21.53.21.81.2-1.01.2-1.1-1.3-1.3-1.31.21.21.1-1.0
Short access total infusions0.50.62.01.40.9-0.50.8-0.7-0.6-0.6-0.90.70.70.8-0.6
Short access day 1 locomotion0.10.10.80.90.4-0.10.3-0.3-0.3-0.3-0.3-0.00.30.40.1
Short access day 10 total locomotion0.20.41.00.60.5-0.20.6-0.5-0.4-0.4-0.81.00.60.4-1.0
Short access total locomotion0.40.50.91.00.8-0.30.7-0.7-0.7-0.7-0.70.70.70.7-0.7
One hour access (0.3 mA shock)0.70.81.4-0.5-0.70.5-0.90.81.01.00.9-1.0-0.8-0.71.2
Compulsive drug intake1.61.92.3-1.1-1.51.3-1.41.51.51.51.2-1.3-1.4-1.41.2
One hour access (shock baseline)0.20.30.60.80.6-0.70.5-0.6-0.5-0.5-0.40.30.60.7-0.2
Social response proportion0.20.20.40.10.6-0.50.5-0.6-0.3-0.3-0.20.30.60.6-0.6
Social responses0.10.10.2-0.3-0.40.3-0.10.20.40.4-0.00.2-0.2-0.2-0.2
Social time0.00.00.1-0.10.2-0.10.1-0.20.20.20.2-0.00.30.30.1
Soleus weight16.548.650.3-6.6-6.96.9-7.17.07.07.07.0-7.0-7.0-7.07.0
Bone: stiffness0.81.32.1-1.5-1.31.2-1.01.11.21.20.9-0.8-1.1-1.10.8
Tibialis anterior weight13.947.049.2-6.7-6.67.0-6.96.97.07.06.9-6.8-6.7-6.96.9
Time to tail flick, vehicle, before self-admin0.20.20.60.30.2-0.40.4-0.3-0.5-0.5-0.60.80.40.4-0.8
Time to tail flick, vehicle, after self-admin1.11.53.20.61.8-1.51.2-1.6-1.2-1.2-0.50.51.21.5-0.8
Time to tail flick, test, before self-admin1.91.92.81.71.4-1.31.4-1.3-1.2-1.2-1.51.61.21.3-1.6
Time to tail flick, test, after self-admin3.73.97.01.82.6-2.01.8-2.2-2.3-2.3-1.11.02.42.1-1.0
Delta time to tail flick, vehicle, before/after SA1.01.02.60.71.6-1.21.0-1.3-1.0-1.0-0.50.41.01.1-0.5
Delta time to tail flick, test, before/after SA0.10.10.4-0.40.30.0-0.2-0.1-0.3-0.30.5-0.60.30.00.6
Tibia length0.00.10.3-0.20.2-0.40.4-0.4-0.4-0.4-0.20.40.30.5-0.5
Ambulatory time before self-admin0.10.20.60.40.8-0.30.3-0.6-0.5-0.50.2-0.30.50.40.2
Ambulatory time after self-admin0.40.50.8-0.7-0.40.6-0.70.60.90.90.6-0.8-0.6-0.70.8
Bone: tissue strength1.41.41.71.31.1-1.11.2-1.2-1.2-1.2-1.21.21.31.2-1.2
Total heroin consumption1.21.42.8-1.0-0.71.1-1.21.00.70.71.6-1.7-1.0-1.01.6
Bone: trabecular number1.42.32.91.71.5-1.51.5-1.4-1.4-1.4-1.71.71.41.4-1.6
Bone: trabecular spacing0.00.00.1-0.2-0.00.2-0.20.10.20.20.3-0.4-0.2-0.20.2
Bone: trabecular thickness0.50.60.90.90.8-0.80.8-0.8-0.8-0.8-0.70.80.80.8-0.7
Bone: trabecular tissue density4.56.67.8-2.2-2.82.7-2.62.72.62.62.3-2.5-2.7-2.72.5
Water consumed over 24 hours0.30.30.60.30.5-0.70.6-0.7-0.6-0.6-0.40.50.70.7-0.5
Number of responses in last shaping day0.10.10.20.20.3-0.30.3-0.5-0.3-0.30.2-0.10.30.40.1