Hub : Genes

Adam10

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression Adam10 0.01 0.01 7.3e-03 0.01 0.01 0.01 0.01 2.3e-02 1.5e-02 1.2e-02 2.5e-02
2 PL gene expression Adam10 0.05 0.06 8.2e-05 0.04 0.04 0.04 0.04 2.4e-05 4.1e-05 2.3e-05 2.4e-05
3 Brain mRNA stability Adam10 0.35 0.2 4.7e-13 0.14 0.13 0.13 0.14 3.5e-13 2.1e-12 7.2e-12 5.4e-13
4 Brain gene expression Adam10 0.19 0.13 0.0e+00 0.2 0.21 0.21 0.21 2.2e-18 2.4e-19 3.1e-19 4.0e-19
5 PL mRNA stability Adam10 0.17 0.12 1.8e-14 0.13 0.14 0.13 0.13 6.8e-14 1.7e-14 3.8e-14 3.4e-14
6 OFC mRNA stability Adam10 0.18 0.15 3.3e-03 0.09 0.09 0.09 0.1 3.6e-03 3.9e-03 3.3e-03 2.6e-03
7 IL mRNA stability Adam10 0.21 0.17 7.8e-04 0.1 0.08 0.1 0.08 1.9e-03 5.8e-03 2.2e-03 5.4e-03
8 Liver gene expression Adam10 0.02 0.02 7.8e-03 0.01 0.01 0.01 0 4.4e-02 5.3e-02 5.6e-02 7.5e-02
9 Adipose mRNA stability Adam10 0.1 0.07 3.6e-12 0.09 0.09 0.09 0.09 1.3e-10 1.6e-10 1.8e-10 1.7e-10
10 pVTA gene expression Adam10 0.07 0.09 3.8e-03 0.03 0.03 0.03 0.03 2.2e-03 3.6e-03 2.7e-03 3.1e-03
11 IL gene expression Adam10 0.35 0.23 5.3e-06 0.17 0.18 0.18 0.18 7.2e-05 5.2e-05 5.3e-05 3.9e-05
12 BLA mRNA stability Adam10 0.14 0.12 1.6e-06 0.09 0.09 0.1 0.1 1.9e-05 2.2e-05 5.7e-06 1.0e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.50.91.3-1.0-0.70.90.9-0.8-0.90.91.1-1.1-0.90.81.0
Area under the delay curve0.00.00.10.2-0.40.20.1-0.3-0.10.1-0.30.3-0.20.2-0.2
BMI with tail6.924.026.75.04.9-5.0-4.94.74.7-4.7-5.25.04.9-4.8-5.0
BMI without tail1.47.79.32.52.4-2.8-2.92.72.8-2.8-3.13.02.7-2.7-2.9
Body weight4.821.123.34.84.8-4.8-4.64.54.4-4.4-4.74.64.6-4.5-4.4
Weight adjusted by age2.26.67.82.02.6-2.4-2.72.62.8-2.8-2.62.42.7-2.7-2.4
Bone surface0.00.10.20.30.5-0.3-0.30.40.2-0.2-0.1-0.10.3-0.4-0.1
Bone volume0.00.00.1-0.10.2-0.10.00.1-0.00.00.2-0.30.0-0.10.1
Breakpoint value in progressive ratio session0.50.81.40.60.6-0.9-1.00.90.9-0.8-1.01.21.0-0.9-1.1
Number of licking bursts0.82.43.9-2.0-1.71.51.5-1.4-1.51.51.6-1.5-1.51.51.4
Context. condit. distance diff. score0.91.11.6-0.6-0.91.01.1-1.1-1.11.10.9-0.9-1.31.21.0
Locomotion velocity, session 11.41.63.10.91.7-1.3-1.21.51.5-1.5-0.60.71.4-1.4-0.9
Locomotion distance, session 10.20.30.8-0.7-0.00.40.5-0.3-0.30.30.9-0.7-0.40.40.7
Locomotion velocity, session 20.20.30.70.10.9-0.5-0.40.60.5-0.5-0.20.30.7-0.5-0.4
Locomotion distance, session 20.20.20.6-0.20.8-0.3-0.40.60.6-0.60.10.30.6-0.5-0.3
Locomotion velocity, session 30.00.00.10.00.2-0.00.10.10.2-0.20.4-0.40.2-0.00.3
Locomotion distance, session 31.71.92.6-1.4-1.31.31.5-1.3-1.31.31.6-1.6-1.31.31.5
Stereotopy head waving bouts, day 30.70.81.81.30.7-0.9-0.90.80.7-0.7-1.21.00.7-0.8-0.8
Stereotopy head waving duration, day 30.81.02.21.50.8-0.9-1.00.80.7-0.7-1.31.20.8-0.9-1.0
Locomotion velocity, session 71.61.82.9-1.6-1.11.21.4-1.2-1.21.21.7-1.5-1.21.21.4
Locomotion distance, session 71.62.13.2-1.8-1.31.31.5-1.3-1.41.41.7-1.2-1.51.41.3
Stereotopy head waving bouts, day 71.21.42.61.60.9-1.1-1.21.00.9-0.9-1.61.31.1-1.0-1.3
Stereotopy head waving duration, day 70.91.22.71.60.8-0.9-1.10.80.8-0.8-1.61.21.0-0.9-1.1
Locomotion velocity, session 80.40.51.30.41.1-0.7-0.60.90.8-0.8-0.10.30.8-0.7-0.4
Locomotion distance, session 80.50.81.4-0.9-0.50.90.9-0.8-0.80.81.2-0.9-0.90.90.9
Degree of sensitization distance0.20.20.4-0.7-0.50.50.4-0.5-0.50.50.4-0.1-0.60.50.3
Degree of sensitization stereotypy0.60.71.31.10.6-0.7-0.80.70.7-0.7-1.20.90.9-0.7-0.9
Conditioned locomotion0.10.10.4-0.4-0.30.60.3-0.4-0.20.20.3-0.3-0.30.40.3
Cocaine response after cond. corrected2.84.24.71.92.1-2.0-2.12.12.2-2.2-2.12.02.1-2.1-2.1
Cocaine response after cond. not corrected1.92.73.21.41.8-1.5-1.61.71.8-1.8-1.51.61.7-1.7-1.6
Cocaine response before conditioning0.91.11.4-0.9-0.91.01.1-1.0-1.11.11.2-1.1-0.91.01.2
Saline control response0.10.10.40.7-0.00.30.1-0.3-0.20.2-0.20.0-0.20.20.2
Bone: connectivity density0.91.52.0-1.3-1.11.41.2-1.1-1.11.11.3-1.4-1.11.21.3
Bone: cortical apparent density1.01.62.0-1.3-1.41.31.3-1.3-1.21.21.2-1.3-1.31.31.2
Bone: cortical area0.00.10.30.00.0-0.00.3-0.1-0.10.10.5-0.6-0.10.10.5
Bone: cortical porosity1.11.21.6-1.3-1.11.01.1-1.1-1.11.11.1-1.1-0.91.01.1
Bone: cortical porosity1.61.82.5-1.6-1.31.31.3-1.3-1.41.41.3-1.3-1.21.31.3
Bone: cortical thickness1.52.63.4-1.6-1.51.51.7-1.5-1.51.51.8-1.8-1.51.51.8
Bone: cortical thickness0.60.71.1-0.8-0.80.80.9-0.7-0.70.71.0-1.1-0.70.71.0
Bone: cortical tissue density0.91.51.9-1.2-1.41.31.2-1.3-1.11.11.2-1.2-1.21.21.2
Condit. Reinf. active minus inactive responses0.00.00.10.20.2-0.00.10.0-0.00.00.2-0.20.0-0.00.2
Condit. Reinf. active-inactive response ratio0.40.40.6-0.4-0.70.70.7-0.7-0.60.60.7-0.6-0.60.70.8
Condit. Reinf. active responses0.40.51.01.01.0-0.8-0.60.70.7-0.7-0.50.50.8-0.8-0.5
Condit. Reinf. inactive responses1.11.42.11.31.4-1.2-1.11.21.3-1.3-1.01.01.3-1.2-0.9
Incentive salience index mean0.00.10.20.40.4-0.3-0.00.20.2-0.20.2-0.20.2-0.20.3
Condit. Reinf. lever presses0.00.10.20.00.2-0.20.10.10.1-0.10.4-0.30.1-0.10.3
Condit. Reinf. active minus inactive responses2.84.35.42.12.3-2.3-2.12.22.1-2.1-1.91.62.1-2.2-1.6
Condit. Reinf. active-inactive response ratio0.71.11.31.11.0-1.1-1.11.11.0-1.0-1.20.81.0-1.1-0.8
Condit. Reinf. active responses1.92.73.61.81.9-1.9-1.61.81.8-1.8-1.31.01.7-1.8-1.1
Condit. Reinf. inactive responses0.10.20.40.20.6-0.5-0.10.50.4-0.40.4-0.30.4-0.40.2
Condit. Reinf. lever presses0.50.72.1-0.7-0.50.50.9-0.6-0.60.61.1-1.5-0.70.61.3
Condit. Reinf. lever reinforcers received1.31.92.71.61.7-1.6-1.31.51.5-1.5-1.00.71.4-1.5-0.7
Conditioned reinforcement - actives0.10.20.80.30.0-0.2-0.3-0.00.3-0.3-0.90.90.1-0.0-0.8
Conditioned reinforcement - inactives0.00.10.4-0.4-0.60.00.3-0.4-0.20.20.10.1-0.30.5-0.0
Conditioned locomotion0.20.30.6-0.3-0.70.70.5-0.8-0.50.50.0-0.0-0.60.60.2
Patch foraging indifference point 0 sec0.30.92.21.01.1-1.0-0.71.01.5-1.5-0.30.20.9-0.8-0.2
Patch foraging indifference point AUC0.10.21.00.11.0-0.6-0.30.5-0.00.0-0.00.00.6-0.5-0.1
Delay disc. indifference point, 0s delay0.30.30.7-0.3-0.80.60.6-0.7-0.40.40.3-0.4-0.50.70.5
Delay disc. indifference point, 16s delay0.20.30.6-0.2-0.80.60.5-0.7-0.60.6-0.00.2-0.60.6-0.0
Delay disc. indifference point, 2s delay0.10.10.5-0.2-0.70.40.2-0.4-0.20.2-0.20.1-0.30.2-0.2
Delay disc. indifference point, 24s delay0.20.30.50.1-0.70.60.5-0.7-0.60.60.3-0.2-0.50.50.3
Delay disc. indifference point, 4s delay0.10.20.3-0.2-0.50.50.4-0.6-0.30.30.0-0.1-0.50.50.2
Delay disc. indifference point, 8s delay0.00.10.20.2-0.0-0.1-0.20.10.1-0.1-0.30.40.1-0.1-0.5
Indifference point function ln k0.10.40.60.60.1-0.4-0.70.50.8-0.8-0.70.80.6-0.5-0.7
Indifference point function log k0.10.40.60.60.1-0.4-0.70.50.8-0.8-0.70.80.6-0.5-0.7
Patch foraging total patch changes 0 sec0.41.02.51.01.1-1.1-0.81.11.6-1.6-0.40.31.1-0.9-0.3
Patch foraging total patch changes 12 sec0.10.20.40.60.6-0.4-0.10.30.4-0.40.1-0.40.3-0.20.4
Patch foraging total patch changes 18 sec0.10.30.60.80.7-0.7-0.50.60.6-0.6-0.30.20.7-0.5-0.3
Patch foraging total patch changes 24 sec0.20.51.20.41.0-0.7-0.50.91.1-1.10.1-0.20.9-0.70.1
Patch foraging total patch changes 6 sec0.61.12.40.81.6-1.2-0.91.11.2-1.2-0.50.61.0-1.0-0.7
Patch foraging time to switch 0 sec0.72.84.7-1.7-2.21.81.6-1.9-1.61.61.3-1.2-1.91.91.2
Patch foraging water rate 0 sec1.14.35.41.82.3-2.1-2.12.22.3-2.3-1.71.82.3-2.2-1.6
Patch foraging water rate 12 sec1.76.88.52.42.8-2.9-2.72.92.7-2.7-2.12.12.8-2.9-2.1
Patch foraging water rate 18 sec0.30.61.40.70.7-0.7-0.80.91.2-1.2-0.40.50.8-0.8-0.4
Patch foraging water rate 24 sec0.40.51.10.40.6-1.0-0.70.90.9-0.9-0.30.50.7-0.9-0.6
Patch foraging water rate 6 sec1.62.33.51.91.6-1.4-1.51.51.6-1.6-1.31.31.6-1.5-1.2
Seeking ratio, delayed vs. immediate footshock0.50.71.00.60.6-1.0-0.80.90.9-0.9-0.70.80.8-0.8-0.7
Distance traveled before self-admin0.10.30.6-0.2-0.70.20.1-0.6-0.50.5-0.60.8-0.50.3-0.6
Distance traveled after self-admin0.71.21.81.20.6-0.9-1.10.91.3-1.2-1.21.30.9-1.0-1.3
Extensor digitorum longus weight8.132.235.05.45.2-5.6-5.85.75.8-5.8-5.95.75.7-5.6-5.7
Bone: elastic displacement0.30.30.60.50.5-0.6-0.60.50.3-0.3-0.80.70.6-0.6-0.7
Bone: elastic work0.00.00.1-0.00.2-0.2-0.10.20.1-0.1-0.00.00.2-0.2-0.1
Bone: endosteal estimation2.15.16.82.62.4-2.3-2.22.32.2-2.2-2.12.02.3-2.2-2.0
Bone: endosteal perimeter3.07.48.42.92.9-2.8-2.72.82.7-2.7-2.62.52.8-2.7-2.5
Epididymis fat weight0.00.00.10.0-0.3-0.1-0.1-0.0-0.10.1-0.2-0.00.00.0-0.1
Delta time in closed arm before/after self-admin1.21.22.2-1.5-1.01.01.0-1.0-0.90.91.2-1.3-0.91.11.1
Delta time in open arm before/after self-admin0.10.10.2-0.5-0.10.40.4-0.3-0.30.30.5-0.5-0.20.30.5
Diff in mean of infusions in LGA sessions0.81.41.81.31.3-1.1-1.11.11.1-1.1-1.21.21.2-1.1-1.1
Delay discount exponential model param0.00.10.2-0.30.3-0.10.00.2-0.0-0.00.4-0.40.1-0.10.3
Extinction: sum of active levers before priming0.30.40.80.90.7-0.3-0.70.60.7-0.7-0.50.70.6-0.5-0.5
Active lever presses in extinction session 60.50.50.90.70.5-0.5-0.70.60.5-0.5-0.80.80.8-0.6-0.9
Bone: final force0.30.40.90.60.9-0.9-0.60.80.8-0.8-0.20.20.6-0.7-0.3
Bone: final moment0.10.10.30.20.5-0.5-0.10.40.4-0.40.2-0.30.2-0.30.1
Food consumed during 24 hour testing period0.51.02.01.41.0-0.9-1.00.80.9-0.9-1.21.10.8-0.8-1.0
Glucose1.01.62.31.21.5-1.3-1.21.31.3-1.3-1.11.11.3-1.3-1.2
Heart weight1.01.63.11.71.0-1.0-1.20.91.1-1.1-1.81.60.8-1.1-1.5
Delay discount hyperbolic model param0.00.10.2-0.10.4-0.3-0.10.30.1-0.10.3-0.30.2-0.20.2
Intermittent access intake day 1-15 change0.21.11.9-1.1-1.11.41.0-1.2-0.90.90.7-0.9-1.11.20.9
Intermittent access intake escalation0.10.71.3-0.9-1.01.20.8-0.9-0.50.50.7-0.9-0.70.90.8
Intermittent access intake escalation 20.00.00.3-0.0-0.30.50.0-0.30.1-0.1-0.30.2-0.10.2-0.2
Intermitt. access day 1 inactive lever presses0.33.84.7-2.0-1.81.82.0-1.9-1.81.81.9-2.1-2.01.82.2
Intermitt. access day 15 inactive lever presses0.00.10.50.70.20.0-0.2-0.10.0-0.0-0.70.50.10.1-0.4
Intermitt. access escalation Index0.20.51.91.40.6-0.7-0.60.60.6-0.6-0.70.90.6-0.4-0.5
Intermittent access day 1 total infusions0.30.91.2-1.1-1.10.91.0-1.0-1.11.10.9-0.7-1.01.00.7
Intermittent access day 15 total infusions0.81.92.7-1.4-1.61.51.4-1.5-1.11.11.2-1.3-1.31.51.3
Intermittent access terminal intake (last 3 days)0.50.81.5-1.2-1.11.10.9-1.0-0.70.70.6-0.7-1.01.00.6
Intermittent access total infusions0.30.40.7-0.8-0.80.70.6-0.7-0.50.50.5-0.4-0.70.70.4
Intermittent access day 1 locomotion1.62.93.3-1.6-1.81.71.8-1.8-1.81.81.6-1.7-1.81.71.6
Intermittent access day 15 total locomotion0.62.43.7-1.6-1.81.91.5-1.7-1.41.31.3-1.6-1.61.61.4
Intermittent access total locomotion0.10.10.3-0.1-0.50.40.1-0.30.0-0.0-0.2-0.2-0.20.20.1
Intermittent access standard deviation0.10.50.8-0.9-0.80.90.6-0.7-0.70.70.5-0.6-0.70.70.4
Left kidney weight1.07.79.82.82.5-2.7-2.82.62.7-2.7-3.12.92.6-2.7-3.0
Right kidney weight1.611.113.43.43.2-3.4-3.33.13.2-3.2-3.73.63.1-3.2-3.5
Cocaine induced anxiety0.10.10.30.2-0.60.40.3-0.5-0.50.50.1-0.1-0.50.30.2
Post-drug Anxiety2.32.63.0-1.3-1.71.71.6-1.7-1.71.71.5-1.5-1.71.61.5
Baseline Anxiety0.60.92.0-1.4-0.70.80.9-0.8-0.90.91.1-1.1-0.80.91.0
Tail length0.00.00.1-0.3-0.20.1-0.0-0.00.1-0.1-0.10.0-0.10.10.1
Length with tail0.62.63.41.61.9-1.7-1.61.71.6-1.6-1.41.41.6-1.7-1.3
Length without tail2.412.616.83.94.1-3.8-3.53.63.3-3.3-3.23.23.6-3.7-3.2
Times rat made contact with spout0.60.71.3-0.6-1.01.20.7-1.0-0.90.90.3-0.4-1.01.00.4
Lifetime Intake0.20.20.9-1.0-0.60.40.4-0.4-0.30.30.4-0.3-0.40.50.2
Liver weight, left3.76.38.12.22.9-2.6-2.62.72.5-2.5-2.32.22.5-2.7-2.2
Liver weight, right1.32.33.91.42.0-1.8-1.41.71.6-1.6-1.21.31.5-1.6-1.2
Locomotor activity6.39.912.93.63.0-2.9-3.23.03.1-3.1-3.33.33.0-3.0-3.1
Locomotor testing distance2.56.28.42.92.4-2.2-2.62.42.3-2.3-2.82.72.4-2.4-2.6
Locomotor testing rearing0.93.34.01.71.5-1.7-1.81.82.0-2.0-1.91.91.7-1.7-1.9
Locomotion in novel chamber0.20.30.7-0.2-0.40.60.5-0.5-0.20.20.5-0.8-0.50.50.9
Locomotion in novel chamber post-restriction0.30.91.3-0.9-0.81.01.0-1.1-0.90.90.8-0.8-1.21.10.8
Fecal boli incidents, locomotor time 10.10.20.50.7-0.10.20.3-0.4-0.70.70.0-0.2-0.50.30.2
Change in fecal boli incidents, locomotor task0.10.10.9-0.90.2-0.1-0.20.30.3-0.30.10.30.1-0.3-0.1
Time >=10cm from walls, locomotor time 10.20.21.81.30.3-0.3-0.40.30.1-0.1-0.50.40.2-0.3-0.5
Bouts of movement, locomotor time 10.10.10.30.20.2-0.3-0.30.40.6-0.6-0.4-0.20.5-0.20.0
Total resting periods, locomotor time 10.10.20.60.00.1-0.3-0.30.40.7-0.8-0.3-0.10.5-0.2-0.0
Rest time, locomotor task time 10.00.10.2-0.50.10.0-0.10.10.4-0.40.1-0.10.0-0.00.0
Distance moved, locomotor task time 10.00.10.3-0.10.00.30.3-0.3-0.60.60.3-0.2-0.20.30.3
Vertical activity count, locomotor time 10.00.20.3-0.3-0.40.50.4-0.6-0.40.40.2-0.2-0.50.50.3
Time >=10cm from walls, locomotor time 20.00.10.30.60.4-0.3-0.10.3-0.00.00.1-0.10.1-0.20.0
Bouts of movement, locomotor time 20.51.62.61.41.0-1.1-1.31.11.0-1.0-1.61.41.2-1.1-1.4
Total resting periods, locomotor time 20.41.72.81.30.9-1.1-1.41.21.2-1.2-1.71.51.2-1.1-1.6
Rest time, locomotor task time 20.10.20.4-0.5-0.60.50.5-0.4-0.30.30.5-0.6-0.50.50.5
Distance moved, locomotor task time 20.00.00.20.30.40.00.00.0-0.20.20.2-0.20.10.00.1
Vertical activity count, locomotor time 20.20.50.8-0.6-0.70.90.7-0.9-0.60.60.4-0.3-0.90.90.4
Light reinforcement 11.46.59.43.12.5-2.5-2.52.62.7-2.7-2.42.32.5-2.5-2.2
Light reinforcement 20.10.10.4-0.3-0.30.10.4-0.2-0.30.30.6-0.6-0.30.20.5
Bone: marrow area2.05.06.62.62.4-2.3-2.22.22.2-2.2-2.12.02.3-2.2-2.0
Bone: maximum diameter2.04.05.22.12.3-2.1-1.92.12.0-2.0-1.71.62.1-2.0-1.7
Bone: maximum force0.20.40.60.70.8-0.8-0.60.70.7-0.7-0.40.30.7-0.7-0.4
Bone: maximum moment0.00.10.20.30.4-0.4-0.20.30.3-0.30.0-0.10.3-0.3-0.0
Mean time between licks in bursts0.10.50.8-0.7-0.90.90.7-0.8-0.90.90.5-0.3-0.70.80.6
Mean num. licks in bursts0.41.02.21.50.9-0.7-1.00.70.8-0.8-1.31.10.8-0.8-1.1
Cd content in liver1.41.62.1-1.1-1.51.21.2-1.3-1.31.31.1-1.1-1.41.31.2
Co content in liver1.31.52.0-1.4-1.41.41.2-1.3-1.31.31.1-1.0-1.21.31.1
Cu content in liver0.00.00.0-0.20.10.0-0.00.10.2-0.20.1-0.10.2-0.1-0.0
Fe content in liver0.30.40.90.90.8-0.6-0.60.60.5-0.5-0.50.30.6-0.6-0.3
K content in liver1.91.92.81.31.4-1.2-1.41.41.4-1.4-1.31.11.7-1.4-1.2
Mg content in liver1.51.62.11.11.3-1.2-1.31.31.3-1.3-1.21.21.5-1.3-1.2
Mn content in liver0.00.00.0-0.1-0.20.20.1-0.2-0.20.20.2-0.1-0.10.20.1
Na content in liver7.99.010.73.03.3-3.1-3.03.13.0-3.0-2.72.73.1-3.1-2.7
Rb content in liver0.50.60.90.60.6-0.6-0.80.80.9-0.9-0.80.81.0-0.7-0.8
Se content in liver0.00.00.10.0-0.20.20.1-0.2-0.20.20.1-0.3-0.10.10.3
Sr content in liver0.00.00.1-0.1-0.10.10.2-0.1-0.30.30.2-0.2-0.20.20.2
Zn content in liver0.00.10.20.10.2-0.1-0.20.20.3-0.3-0.20.00.4-0.2-0.1
Bone: minimum diameter0.00.10.20.50.00.00.3-0.2-0.10.10.3-0.5-0.10.20.4
Time in familiar zone, hab. session 10.00.00.3-0.50.00.10.10.10.0-0.00.3-0.30.0-0.00.1
Time in novel zone, hab. session 10.10.10.10.2-0.10.20.2-0.3-0.30.3-0.0-0.0-0.30.30.1
Total zone transitions, hab. session 10.40.61.1-1.0-0.70.70.7-0.6-0.50.51.0-1.1-0.50.61.1
Total locomotion distance, hab. session 10.00.10.2-0.2-0.10.20.2-0.1-0.20.20.4-0.4-0.20.10.4
Locomotion velocity, hab. session 10.00.00.00.10.0-0.0-0.10.10.1-0.10.0-0.10.0-0.10.2
Time in familiar zone, hab. session 20.10.10.4-0.6-0.10.10.2-0.1-0.30.30.4-0.2-0.30.20.1
Time in novel zone, hab. session 20.00.00.10.3-0.10.20.1-0.2-0.10.10.0-0.2-0.00.20.2
Total zone transitions, hab. session 20.30.40.80.30.9-0.7-0.60.80.7-0.7-0.30.40.8-0.8-0.5
Total locomotion distance, hab. session 20.71.01.10.81.0-0.9-1.01.11.0-1.0-0.91.01.0-1.0-0.9
Locomotion velocity, hab. session 20.40.50.60.50.7-0.7-0.70.80.7-0.7-0.60.70.7-0.8-0.6
Novel to familiar place preference ratio0.81.01.31.01.0-1.1-1.00.91.0-1.0-1.11.01.0-1.0-1.1
Novelty place preference0.81.11.31.01.0-1.1-1.01.01.0-1.0-1.10.91.0-1.0-1.1
Time in novel zone, NPP test1.11.31.51.11.2-1.2-1.11.11.1-1.1-1.21.11.1-1.1-1.2
Total zone transitions, NPP test0.20.40.80.50.9-0.4-0.60.70.7-0.7-0.30.20.8-0.7-0.2
Total locomotion distance, NPP test0.60.91.20.81.0-0.9-0.91.01.1-1.1-0.80.71.0-1.0-0.7
Locomotion velocity, NPP test0.20.30.50.40.6-0.5-0.60.70.7-0.7-0.40.40.7-0.7-0.3
Intraocular pressure0.00.00.1-0.10.1-0.0-0.0-0.1-0.30.3-0.10.4-0.10.0-0.3
Delta distance traveled before/after self-admin1.51.62.81.31.4-1.2-1.21.51.7-1.7-0.70.71.4-1.4-0.8
Delta ambulatory time before/after self-admin0.40.71.31.01.0-0.8-0.81.01.1-1.1-0.30.30.9-0.9-0.3
Parametrial fat weight0.92.12.8-1.7-1.11.41.5-1.4-1.61.61.6-1.4-1.41.41.2
Pavlov. Cond. lever latency0.10.20.3-0.4-0.40.50.4-0.5-0.40.40.4-0.2-0.50.50.2
Pavlov. Cond. magazine entry latency0.60.71.4-1.0-0.60.70.9-0.7-0.70.71.2-1.1-0.70.71.0
Pavlov. Cond. change in total contacts0.00.00.10.3-0.00.0-0.0-0.10.0-0.0-0.3-0.20.20.00.1
Pavlov. Cond. index score0.40.50.9-0.8-0.60.50.7-0.6-0.60.60.9-1.0-0.50.60.9
Pavlov. Cond. latency score0.10.20.5-0.4-0.30.20.4-0.3-0.30.30.5-0.7-0.20.30.6
Pavlov. Cond. lever contacts0.00.00.0-0.00.1-0.2-0.10.20.2-0.20.0-0.10.2-0.20.1
Pavlov. Cond. magazine entry number0.81.01.41.10.9-0.8-1.10.91.0-1.0-1.21.20.9-0.9-1.2
Pavlov. Cond. intertrial magazine entries0.10.20.30.40.6-0.3-0.30.40.5-0.5-0.10.30.4-0.4-0.4
Pavlov. Cond. lever-magazine prob. diff.0.20.30.5-0.7-0.40.30.5-0.4-0.40.40.6-0.7-0.30.40.7
Pavlov. Cond. response bias0.30.40.6-0.8-0.50.40.6-0.5-0.50.50.7-0.8-0.40.50.7
Pavlov. Cond. lever latency0.20.31.20.40.1-0.3-0.50.30.2-0.2-0.91.10.3-0.3-1.0
Pavlov. Cond. magazine entry latency2.94.15.3-1.8-2.02.12.0-2.0-1.91.92.0-2.3-2.02.12.3
Pavlov. Cond. change in total contacts0.20.51.3-0.4-0.40.60.7-0.6-0.60.50.9-1.0-0.60.61.2
Pavlov. Cond. index score0.71.22.3-1.0-0.81.01.1-0.9-0.80.81.3-1.5-0.91.01.5
Pavlov. Cond. latency score0.40.71.6-0.7-0.60.80.8-0.7-0.60.61.0-1.2-0.70.81.2
Pavlov. Cond. lever contacts0.20.31.1-0.4-0.10.30.5-0.3-0.20.10.8-1.0-0.30.31.0
Pavlov. Cond. magazine entry number3.34.35.62.02.0-2.1-2.12.01.9-1.9-2.22.41.9-2.1-2.3
Pavlov. Cond. intertrial magazine entries0.71.52.41.51.4-1.4-1.21.20.9-0.9-1.11.21.0-1.2-1.2
Pavlov. Cond. lever-magazine prob. diff.0.91.42.5-1.1-0.91.11.2-1.0-0.90.91.4-1.6-1.01.11.5
Pavlov. Cond. response bias1.31.83.3-1.2-1.11.21.4-1.1-1.01.01.6-1.8-1.21.21.8
Time in closed arm before self-admin0.10.20.60.7-0.30.60.3-0.6-0.70.8-0.20.0-0.50.40.0
Time in closed arm after self-admin0.80.91.7-0.3-1.00.90.9-1.1-1.31.30.7-0.7-1.01.00.8
Time in open arm before self-admin0.50.71.10.10.6-1.1-0.80.81.0-1.0-0.71.00.7-0.6-0.9
Time in open arm after self-admin0.30.40.80.00.8-0.6-0.50.70.9-0.9-0.30.50.6-0.6-0.5
Bone: periosteal estimation1.12.53.81.91.8-1.7-1.51.61.6-1.6-1.31.21.7-1.6-1.3
Bone: periosteal perimeter1.73.44.32.12.0-2.0-1.81.91.9-1.9-1.61.51.9-1.8-1.6
Bone: post-yield work0.10.10.30.50.3-0.1-0.30.20.3-0.3-0.30.30.4-0.1-0.3
Progressive ratio test 1 active lever presses0.10.10.2-0.5-0.30.30.4-0.4-0.40.40.3-0.2-0.40.40.1
Progressive ratio test 1 breakpoint0.10.20.3-0.6-0.40.40.5-0.5-0.50.50.4-0.2-0.40.50.2
Progressive ratio test 1 inactive lever presses1.13.04.6-2.1-1.51.51.8-1.6-1.61.62.0-1.8-1.61.71.7
Progressive ratio test 2 active lever presses0.10.20.5-0.10.1-0.2-0.40.20.6-0.6-0.50.50.3-0.2-0.7
Progressive ratio test 2 breakpoint0.10.20.4-0.10.1-0.2-0.30.20.6-0.6-0.50.50.3-0.2-0.6
Progressive ratio test 2 inactive lever presses0.10.20.5-0.7-0.60.40.5-0.6-0.30.30.3-0.4-0.50.50.3
Incentive Sensitization - Responses0.10.20.60.10.0-0.2-0.50.20.7-0.7-0.70.60.2-0.3-0.7
Incentive Sensitization - Breakpoint0.10.10.4-0.1-0.1-0.1-0.30.10.6-0.6-0.60.40.1-0.1-0.6
Sum of active levers in priming session hrs 5-60.10.10.20.4-0.0-0.1-0.30.20.3-0.3-0.40.50.3-0.2-0.4
Progressive ratio0.51.63.7-1.1-1.91.31.2-1.5-1.41.40.5-0.8-1.31.30.6
Food seeking constrained by brief footshock0.20.20.40.60.4-0.5-0.50.50.2-0.2-0.40.40.6-0.5-0.5
Seeking ratio, punishment vs. effort2.55.69.42.33.1-2.5-2.42.72.4-2.4-1.71.92.6-2.5-1.7
Retroperitoneal fat weight0.00.20.5-0.00.10.30.4-0.3-0.40.40.5-0.7-0.30.30.6
Reaction time number correct0.51.93.01.01.3-1.3-1.51.31.3-1.3-1.41.71.4-1.4-1.7
Reaction time mean minus median0.00.10.4-0.50.2-0.30.20.1-0.10.10.3-0.7-0.0-0.10.6
Reaction time mean minus median AUC0.10.61.6-1.2-0.40.30.7-0.5-0.60.60.9-1.2-0.50.51.1
Reaction time num false alarms0.40.71.2-0.6-0.70.70.8-0.7-1.01.01.1-0.8-0.90.80.9
Reaction time num false alarms AUC0.10.30.6-0.2-0.20.30.5-0.3-0.70.70.8-0.6-0.50.40.6
Reaction time trials correct on left0.51.93.01.01.3-1.3-1.51.31.3-1.3-1.41.71.4-1.4-1.7
Reaction time trials on left0.62.13.21.11.3-1.3-1.51.41.4-1.4-1.41.71.5-1.4-1.8
Reaction time mean1.53.35.6-2.4-1.51.51.8-1.5-1.81.82.0-2.1-1.51.62.1
Reaction time mean AUC1.02.34.2-2.1-1.21.21.5-1.3-1.41.41.7-1.8-1.31.31.8
Median of all reaction times3.75.88.4-2.9-2.22.22.4-2.2-2.42.32.6-2.6-2.12.22.7
Reaction time omissions0.20.30.5-0.20.5-0.7-0.50.60.7-0.7-0.40.40.5-0.6-0.4
Reaction time false alarm rate1.21.62.3-0.9-1.01.11.3-1.1-1.31.31.5-1.5-1.31.21.5
Reaction time premature initiation rate1.42.22.80.71.6-1.6-1.61.71.4-1.4-1.31.51.5-1.6-1.6
Reaction time premature initiations1.23.64.61.02.0-2.0-2.02.11.8-1.8-1.72.11.9-2.0-2.1
Std. dev. reaction times0.31.12.7-1.7-0.70.61.0-0.8-1.01.01.2-1.4-0.80.71.3
Reaction time trials completed0.62.13.21.11.3-1.3-1.51.41.4-1.4-1.41.71.5-1.4-1.8
Reaction time trials AUC0.51.72.80.91.2-1.2-1.41.31.2-1.2-1.31.61.3-1.3-1.7
Run reversals in cocaine runway, females0.00.00.1-0.2-0.10.30.1-0.10.3-0.30.2-0.00.00.1-0.0
Run reversals in cocaine runway, males0.10.10.10.00.2-0.3-0.20.30.4-0.4-0.20.10.2-0.4-0.1
Latency to leave start box in cocaine runway1.92.63.91.91.5-1.6-1.61.41.5-1.5-1.82.01.2-1.5-1.9
Latency to leave start box in cocaine runway, F0.70.81.91.40.9-0.9-0.90.80.7-0.7-1.01.00.7-0.9-0.9
Latency to leave start box in cocaine runway, M5.45.17.12.12.2-2.1-2.22.02.3-2.3-2.52.61.9-2.0-2.7
Std. dev. time between licks in bursts0.40.71.00.81.0-1.0-0.81.01.0-1.0-0.50.41.0-0.9-0.4
Total sessions with >9 infusions0.20.21.1-1.1-0.30.10.4-0.3-0.10.10.6-0.4-0.30.40.3
Short access day 1 total inactive lever presses0.40.81.4-1.2-1.10.80.9-0.9-0.80.80.9-0.8-0.90.90.8
Short access day 10 total inactive lever presses0.21.52.0-0.7-1.11.31.3-1.4-1.41.41.0-1.2-1.21.21.3
Short access day 1 total infusions0.20.31.5-1.2-0.70.30.5-0.6-0.50.50.3-0.2-0.60.6-0.0
Short access day 10 total infusions0.91.63.4-1.8-1.21.01.2-1.1-1.31.31.3-1.2-1.21.11.0
Short access total infusions0.50.72.2-1.5-0.90.50.8-0.7-0.60.60.9-0.7-0.70.80.6
Short access day 1 locomotion0.10.21.0-1.0-0.40.10.3-0.3-0.30.30.30.0-0.30.4-0.1
Short access day 10 total locomotion0.10.41.0-0.6-0.50.20.6-0.5-0.40.40.8-1.0-0.60.41.0
Short access total locomotion0.30.50.9-1.0-0.80.30.7-0.7-0.70.70.7-0.7-0.70.70.7
One hour access (0.3 mA shock)0.60.71.40.40.7-0.5-0.90.81.0-1.0-0.91.00.8-0.7-1.2
Compulsive drug intake1.31.92.31.11.5-1.3-1.41.51.5-1.5-1.21.31.4-1.4-1.2
One hour access (shock baseline)0.10.30.7-0.8-0.60.70.5-0.6-0.50.50.4-0.3-0.60.70.2
Social response proportion0.20.20.4-0.1-0.60.50.5-0.6-0.30.30.2-0.3-0.60.60.6
Social responses0.10.10.20.40.4-0.3-0.10.20.4-0.40.0-0.20.2-0.20.2
Social time0.00.00.10.1-0.20.10.1-0.20.2-0.2-0.20.0-0.30.3-0.1
Soleus weight16.548.550.36.56.9-6.9-7.17.07.0-7.0-7.07.07.0-7.0-7.0
Bone: stiffness0.71.32.31.51.3-1.2-1.01.11.2-1.2-0.90.81.1-1.1-0.8
Tibialis anterior weight13.647.049.26.66.6-7.0-6.96.97.0-7.0-6.96.86.7-6.9-6.9
Time to tail flick, vehicle, before self-admin0.20.20.6-0.3-0.20.40.4-0.3-0.50.50.6-0.8-0.40.40.8
Time to tail flick, vehicle, after self-admin0.71.53.2-0.6-1.81.51.2-1.6-1.21.20.5-0.5-1.21.50.8
Time to tail flick, test, before self-admin1.71.92.7-1.6-1.41.31.4-1.3-1.21.21.5-1.6-1.21.31.6
Time to tail flick, test, after self-admin3.73.97.0-1.8-2.62.01.8-2.2-2.32.31.1-1.0-2.42.11.0
Delta time to tail flick, vehicle, before/after SA0.91.02.6-0.7-1.61.21.0-1.3-1.01.00.5-0.4-1.01.10.5
Delta time to tail flick, test, before/after SA0.10.10.40.4-0.3-0.0-0.2-0.1-0.30.3-0.50.6-0.30.0-0.6
Tibia length0.00.10.30.2-0.20.40.4-0.4-0.40.40.2-0.4-0.30.50.5
Ambulatory time before self-admin0.10.20.6-0.5-0.80.30.3-0.6-0.50.5-0.20.3-0.50.4-0.2
Ambulatory time after self-admin0.30.50.80.70.4-0.6-0.70.60.9-0.9-0.60.80.6-0.7-0.8
Bone: tissue strength1.41.51.7-1.3-1.11.11.2-1.2-1.21.21.2-1.2-1.31.21.2
Total heroin consumption1.11.32.80.90.7-1.1-1.21.00.7-0.7-1.61.71.0-1.0-1.6
Bone: trabecular number1.22.32.9-1.7-1.51.51.5-1.4-1.41.41.7-1.7-1.41.41.6
Bone: trabecular spacing0.00.00.10.20.0-0.2-0.20.10.2-0.2-0.30.40.2-0.2-0.2
Bone: trabecular thickness0.50.61.0-1.0-0.80.80.8-0.8-0.80.80.7-0.8-0.80.80.7
Bone: trabecular tissue density3.86.67.82.12.8-2.7-2.62.72.6-2.6-2.32.52.7-2.7-2.5
Water consumed over 24 hours0.20.30.6-0.3-0.50.70.6-0.7-0.60.60.4-0.5-0.70.70.5
Number of responses in last shaping day0.10.10.2-0.2-0.30.30.3-0.5-0.30.3-0.20.1-0.30.4-0.1