Hub : Genes

Unc13c

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain alternative polyA XM_017595492.2 0.03 0.02 1.5e-03 0.02 0.03 0.02 0.02 1.0e-02 1.5e-03 2.3e-03 2.6e-03
2 Brain alternative polyA XM_017595495.2 0.04 0.02 1.2e-03 0.02 0.03 0.01 0.03 5.2e-03 1.5e-03 1.6e-02 1.7e-03
3 NAcc mRNA stability Unc13c 0.03 0.02 1.0e-04 0.02 0.02 0.02 0.02 2.0e-03 2.6e-03 2.1e-03 4.0e-03
4 PL gene expression Unc13c 0.03 0.02 1.3e-03 0.03 0.01 0.01 0.02 6.6e-04 8.8e-03 2.4e-02 4.1e-03
5 PL alternative TSS NM_173146.2 0.05 0.04 6.2e-04 0.01 0.01 0.01 0.01 3.0e-02 1.8e-02 4.3e-02 4.9e-02
6 PL alternative TSS XM_017595492.2 0.07 0.05 3.1e-04 0.01 0.02 0.01 0.01 2.0e-02 5.1e-03 1.1e-02 2.1e-02
7 NAcc gene expression Unc13c 0.14 0.06 0.0e+00 0.15 0.16 0.16 0.16 1.2e-16 1.7e-18 7.7e-18 3.5e-18
8 BLA mRNA stability Unc13c 0.15 0.08 6.9e-05 0.1 0.06 0.08 0.09 3.2e-06 3.1e-04 3.6e-05 2.6e-05
9 Brain mRNA stability Unc13c 0.15 0.07 9.6e-08 0.06 0.09 0.07 0.07 3.7e-06 7.6e-09 1.9e-07 3.4e-07
10 Brain gene expression Unc13c 0.18 0.07 2.6e-15 0.14 0.18 0.19 0.19 2.9e-13 5.4e-17 2.3e-17 9.6e-18
11 OFC gene expression Unc13c 0.16 0.09 5.5e-03 0.09 0.08 0.06 0.06 4.3e-03 6.4e-03 1.2e-02 1.5e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.30.51.0-0.80.8-0.9-1.00.2-0.10.7-1.00.00.6-0.7
Area under the delay curve0.10.10.3-0.20.20.1-0.0-0.40.4-0.60.0-0.5-0.40.2
BMI with tail3.711.918.53.7-3.54.14.2-3.12.7-4.33.40.6-2.64.0
BMI without tail1.42.88.51.2-1.01.31.40.3-0.6-2.21.1-1.8-2.92.7
Body weight1.97.813.02.5-2.43.33.3-2.92.6-3.62.70.6-1.83.4
Weight adjusted by age4.04.68.72.3-2.32.32.4-2.01.8-3.02.4-0.3-0.92.5
Bone surface0.10.20.60.4-0.4-0.0-0.1-0.40.3-0.7-0.0-0.7-0.10.8
Bone volume0.10.10.30.2-0.1-0.0-0.1-0.50.5-0.4-0.1-0.10.20.4
Breakpoint value in progressive ratio session0.10.10.50.2-0.20.20.30.0-0.1-0.50.3-0.5-0.70.5
Number of licking bursts1.11.32.9-1.41.2-1.7-1.60.5-0.41.0-1.4-1.20.4-0.5
Context. condit. distance diff. score0.30.41.2-0.30.3-0.4-0.5-0.60.70.50.10.71.1-0.8
Locomotion velocity, session 10.20.30.80.4-0.30.40.40.2-0.3-0.70.2-0.7-0.70.9
Locomotion distance, session 11.31.73.1-1.31.4-1.5-1.51.7-1.80.7-1.1-1.6-0.4-0.3
Locomotion velocity, session 20.40.51.9-0.30.3-0.3-0.40.8-0.8-0.2-0.6-1.4-1.20.3
Locomotion distance, session 21.21.75.7-0.40.6-0.5-0.51.8-2.0-0.5-0.3-2.4-2.10.6
Locomotion velocity, session 31.01.23.8-0.40.4-0.6-0.61.5-1.6-0.0-0.6-1.9-1.60.5
Locomotion distance, session 33.13.35.9-2.02.1-2.0-2.12.4-2.41.6-1.6-1.7-0.5-0.7
Stereotopy head waving bouts, day 32.02.34.01.9-2.01.51.6-1.61.6-0.91.61.81.20.4
Stereotopy head waving duration, day 32.42.85.32.2-2.31.81.9-1.81.8-1.01.12.11.10.2
Locomotion velocity, session 70.80.82.6-0.70.8-0.8-0.91.1-1.10.8-1.6-0.6-0.1-0.9
Locomotion distance, session 71.31.64.0-1.31.3-1.3-1.41.4-1.30.8-2.0-1.4-0.6-0.2
Stereotopy head waving bouts, day 70.70.73.11.2-1.20.60.60.4-0.5-0.71.8-0.5-0.40.1
Stereotopy head waving duration, day 70.81.02.41.4-1.40.80.80.5-0.6-1.01.6-0.8-0.70.3
Locomotion velocity, session 80.70.93.20.5-0.60.10.21.1-1.2-0.70.3-1.8-1.50.5
Locomotion distance, session 80.91.33.8-1.01.0-1.3-1.31.4-1.40.3-0.8-1.9-1.1-0.2
Degree of sensitization distance0.20.20.90.1-0.2-0.1-0.0-0.60.6-0.0-0.90.10.3-0.3
Degree of sensitization stereotypy0.50.62.80.7-0.70.40.40.5-0.6-0.61.7-0.8-0.80.2
Conditioned locomotion0.20.20.7-0.80.9-0.3-0.2-0.30.30.2-0.80.3-0.10.0
Cocaine response after cond. corrected5.46.18.82.9-2.92.82.7-2.72.6-2.53.01.5-0.01.9
Cocaine response after cond. not corrected5.56.010.02.6-2.62.62.5-3.23.2-2.12.72.00.51.7
Cocaine response before conditioning0.40.51.5-1.21.1-0.8-0.8-0.50.60.7-0.90.10.3-0.1
Saline control response0.30.31.30.2-0.3-0.1-0.1-0.50.60.4-0.41.01.2-0.4
Bone: connectivity density1.93.04.8-1.81.8-2.1-2.21.8-1.71.6-2.2-1.20.3-1.4
Bone: cortical apparent density0.60.72.3-0.50.6-0.6-0.70.8-0.71.2-0.10.91.1-1.5
Bone: cortical area1.42.15.80.8-0.80.80.7-2.12.2-0.20.52.42.20.1
Bone: cortical porosity0.70.81.3-1.11.0-0.6-0.6-0.80.90.9-0.61.11.1-0.8
Bone: cortical porosity0.80.91.5-1.21.1-0.8-0.8-0.50.61.1-0.90.81.1-1.1
Bone: cortical thickness1.32.28.8-0.60.6-0.7-0.8-0.60.91.6-0.72.63.0-1.7
Bone: cortical thickness1.01.14.00.0-0.1-0.1-0.1-1.11.30.7-0.52.02.0-0.8
Bone: cortical tissue density0.50.72.1-0.50.6-0.6-0.70.8-0.71.2-0.10.81.0-1.5
Condit. Reinf. active minus inactive responses1.41.63.5-1.41.6-1.0-1.11.5-1.60.3-0.5-1.9-1.50.0
Condit. Reinf. active-inactive response ratio0.30.30.90.1-0.10.30.2-0.70.70.00.70.90.7-0.4
Condit. Reinf. active responses2.73.39.7-1.61.7-1.3-1.32.3-2.40.1-0.7-3.1-2.50.3
Condit. Reinf. inactive responses3.54.213.5-1.51.6-1.5-1.52.6-2.80.1-1.2-3.7-2.60.4
Incentive salience index mean0.81.03.0-1.21.2-0.6-0.80.6-0.7-0.1-0.2-1.7-1.60.6
Condit. Reinf. lever presses0.40.61.8-0.80.8-0.4-0.5-0.30.2-0.4-0.3-1.4-1.30.8
Condit. Reinf. active minus inactive responses1.31.64.21.7-1.71.41.3-0.90.8-1.42.10.3-0.50.9
Condit. Reinf. active-inactive response ratio1.71.73.51.8-1.81.41.3-1.21.1-1.11.91.20.40.4
Condit. Reinf. active responses0.40.61.90.6-0.60.70.7-0.70.7-1.01.4-0.2-0.60.7
Condit. Reinf. inactive responses0.91.12.9-1.71.7-1.3-1.20.6-0.60.7-0.7-1.3-0.6-0.3
Condit. Reinf. lever presses0.81.14.3-0.20.1-0.3-0.3-1.31.50.7-0.11.42.1-0.8
Condit. Reinf. lever reinforcers received0.30.41.60.4-0.40.50.5-0.80.7-0.61.30.1-0.20.4
Conditioned reinforcement - actives0.00.00.1-0.20.1-0.2-0.20.0-0.1-0.0-0.1-0.3-0.30.2
Conditioned reinforcement - inactives0.10.10.3-0.40.3-0.2-0.00.4-0.30.5-0.2-0.00.3-0.6
Conditioned locomotion0.30.41.2-0.60.6-0.2-0.2-0.40.50.6-0.51.10.7-0.8
Patch foraging indifference point 0 sec0.10.10.30.5-0.50.40.30.0-0.1-0.40.5-0.3-0.20.3
Patch foraging indifference point AUC1.51.82.8-1.61.7-1.3-1.41.4-1.50.8-1.1-1.5-1.4-0.4
Delay disc. indifference point, 0s delay2.42.66.6-1.51.6-1.4-1.62.0-2.00.4-1.5-2.6-1.5-0.2
Delay disc. indifference point, 16s delay0.30.31.3-0.10.0-0.2-0.3-0.20.20.4-0.30.81.2-1.1
Delay disc. indifference point, 2s delay0.10.10.3-0.40.4-0.4-0.50.2-0.20.0-0.3-0.6-0.1-0.2
Delay disc. indifference point, 24s delay0.60.61.2-0.90.9-0.9-0.80.3-0.20.7-1.10.10.9-0.9
Delay disc. indifference point, 4s delay0.10.10.4-0.20.30.1-0.2-0.10.1-0.4-0.4-0.6-0.30.2
Delay disc. indifference point, 8s delay0.80.91.90.4-0.40.70.6-0.70.6-1.40.9-1.1-1.31.2
Indifference point function ln k2.12.95.12.2-2.32.01.8-1.71.7-1.41.91.30.81.0
Indifference point function log k2.12.95.12.2-2.32.01.8-1.71.7-1.41.91.30.81.0
Patch foraging total patch changes 0 sec0.10.20.40.6-0.60.50.4-0.10.1-0.50.5-0.1-0.20.4
Patch foraging total patch changes 12 sec0.81.01.6-1.21.3-1.0-1.21.2-1.21.0-0.7-0.6-0.2-1.0
Patch foraging total patch changes 18 sec0.10.20.4-0.40.4-0.6-0.60.2-0.10.6-0.40.20.4-0.5
Patch foraging total patch changes 24 sec1.51.94.5-1.01.2-0.9-0.91.9-2.10.1-1.2-2.1-1.50.4
Patch foraging total patch changes 6 sec1.31.94.8-0.60.8-0.7-0.72.1-2.20.1-1.0-2.1-2.00.1
Patch foraging time to switch 0 sec0.20.41.5-0.20.2-0.4-0.40.4-0.30.7-0.30.31.2-1.1
Patch foraging water rate 0 sec1.42.34.21.6-1.51.71.7-1.41.3-1.71.50.4-1.12.0
Patch foraging water rate 12 sec1.01.62.81.7-1.61.31.3-0.50.4-1.61.5-0.4-1.01.6
Patch foraging water rate 18 sec0.10.10.30.00.10.20.20.4-0.4-0.2-0.4-0.1-0.50.4
Patch foraging water rate 24 sec0.50.71.5-0.80.8-0.7-0.81.2-1.20.8-0.8-0.9-0.5-0.2
Patch foraging water rate 6 sec0.20.30.90.5-0.50.40.2-0.20.2-0.70.4-0.6-0.90.9
Seeking ratio, delayed vs. immediate footshock2.93.45.41.9-1.92.02.0-1.10.9-2.32.0-1.0-2.32.0
Distance traveled before self-admin1.31.43.21.4-1.61.41.3-0.80.7-1.31.8-0.1-0.40.7
Distance traveled after self-admin3.74.15.62.3-2.42.32.2-2.32.2-2.22.40.90.11.5
Extensor digitorum longus weight4.316.928.44.7-4.55.35.2-2.31.7-5.34.2-0.6-4.14.4
Bone: elastic displacement0.10.10.7-0.10.20.1-0.0-0.0-0.0-0.0-0.80.1-0.20.1
Bone: elastic work0.20.20.90.0-0.00.30.1-0.50.60.2-0.50.90.6-0.4
Bone: endosteal estimation2.96.310.82.7-2.72.72.7-2.62.3-3.32.2-0.0-1.53.1
Bone: endosteal perimeter2.04.27.02.2-2.12.32.3-2.22.0-2.61.70.3-1.02.5
Epididymis fat weight1.12.54.4-1.71.8-1.5-1.32.1-2.11.4-1.7-0.7-0.5-1.5
Delta time in closed arm before/after self-admin0.70.72.5-0.10.10.20.2-1.01.10.40.41.61.2-1.1
Delta time in open arm before/after self-admin1.21.22.5-0.30.3-1.1-1.11.6-1.41.1-1.2-0.31.2-1.2
Diff in mean of infusions in LGA sessions2.52.74.81.5-1.61.91.9-2.12.0-1.42.20.8-1.01.0
Delay discount exponential model param0.10.10.40.1-0.1-0.10.00.5-0.40.6-0.00.60.4-0.3
Extinction: sum of active levers before priming0.50.51.0-0.50.4-0.7-0.70.5-0.31.0-0.70.30.9-1.0
Active lever presses in extinction session 60.30.30.90.4-0.50.30.30.3-0.4-0.50.7-0.7-0.90.5
Bone: final force0.81.22.51.1-1.01.31.1-1.61.5-1.20.41.10.40.8
Bone: final moment0.81.32.91.0-0.91.21.0-1.71.7-0.80.31.60.90.4
Food consumed during 24 hour testing period3.34.08.92.0-2.11.61.8-3.03.0-1.61.61.81.31.3
Glucose0.50.71.81.3-1.21.11.20.1-0.2-0.90.70.2-0.40.5
Heart weight0.10.20.6-0.70.8-0.3-0.30.0-0.00.4-0.60.0-0.2-0.5
Delay discount hyperbolic model param0.10.10.30.1-0.1-0.10.10.4-0.40.50.00.50.3-0.3
Intermittent access intake day 1-15 change1.31.23.0-1.11.1-1.3-1.31.5-1.50.4-0.7-1.7-0.5-0.2
Intermittent access intake escalation0.50.52.4-0.50.5-0.7-0.70.8-0.9-0.10.1-1.6-0.60.2
Intermittent access intake escalation 20.50.52.40.1-0.2-0.2-0.10.4-0.5-0.80.6-1.6-0.90.7
Intermitt. access day 1 inactive lever presses0.91.04.90.0-0.20.10.1-1.11.20.6-0.11.62.2-0.6
Intermitt. access day 15 inactive lever presses0.70.71.8-1.11.0-0.8-0.8-0.00.10.9-0.90.71.3-1.0
Intermitt. access escalation Index1.31.12.10.9-0.91.21.1-1.31.2-0.91.50.6-0.71.2
Intermittent access day 1 total infusions0.70.83.50.0-0.10.10.2-0.70.80.8-0.61.91.6-1.0
Intermittent access day 15 total infusions0.20.20.4-0.30.3-0.4-0.40.3-0.20.5-0.50.20.6-0.6
Intermittent access terminal intake (last 3 days)0.10.10.40.0-0.00.20.1-0.50.50.0-0.10.60.6-0.1
Intermittent access total infusions0.70.72.90.4-0.40.20.2-0.91.00.4-0.31.51.7-0.7
Intermittent access day 1 locomotion1.11.14.8-0.20.20.20.2-0.80.90.9-0.62.22.0-1.1
Intermittent access day 15 total locomotion0.50.62.6-0.10.2-0.0-0.0-0.50.60.5-0.41.51.6-0.7
Intermittent access total locomotion0.60.72.40.4-0.40.60.6-1.01.1-0.00.11.51.4-0.1
Intermittent access standard deviation0.20.20.4-0.60.5-0.6-0.5-0.10.20.2-0.3-0.60.3-0.0
Left kidney weight0.82.23.51.3-1.31.81.6-1.91.8-1.71.21.0-0.31.7
Right kidney weight0.41.01.80.7-0.61.31.2-1.00.8-1.30.80.1-1.01.3
Cocaine induced anxiety0.40.40.8-0.90.9-0.8-0.80.3-0.20.6-0.8-0.4-0.2-0.3
Post-drug Anxiety2.83.14.6-1.91.9-1.9-1.92.1-2.11.6-1.8-1.4-0.8-1.5
Baseline Anxiety1.31.33.9-0.91.0-0.9-0.91.9-2.00.9-0.9-0.9-0.6-1.0
Tail length0.61.84.5-1.41.5-1.1-1.11.6-1.70.2-1.0-2.1-1.30.5
Length with tail0.10.30.9-0.30.40.40.3-0.60.6-0.7-0.0-0.2-0.30.9
Length without tail2.55.613.21.8-1.92.52.3-3.63.6-1.72.12.61.21.1
Times rat made contact with spout0.50.61.8-0.50.4-0.6-0.5-1.01.20.5-0.70.71.3-0.4
Lifetime Intake0.60.72.50.0-0.0-0.1-0.2-0.50.60.8-0.81.41.6-1.1
Liver weight, left0.91.52.81.4-1.41.31.2-1.21.1-1.51.30.2-0.41.7
Liver weight, right1.62.76.81.6-1.41.71.7-0.60.3-2.31.7-0.6-1.82.6
Locomotor activity2.23.45.42.2-2.12.32.1-1.91.7-2.12.01.2-0.11.3
Locomotor testing distance1.11.93.11.7-1.81.71.4-1.51.4-1.31.31.20.50.4
Locomotor testing rearing0.20.30.70.8-0.80.80.6-0.40.4-0.50.70.5-0.1-0.2
Locomotion in novel chamber0.70.83.4-0.30.3-0.2-0.6-0.40.50.8-0.71.41.9-1.2
Locomotion in novel chamber post-restriction0.20.30.9-0.50.6-0.4-0.40.6-0.60.3-0.9-0.6-0.40.0
Fecal boli incidents, locomotor time 10.20.30.8-0.70.6-0.30.1-0.30.30.00.9-0.6-0.60.6
Change in fecal boli incidents, locomotor task2.42.36.02.4-2.51.61.5-1.11.1-1.31.01.20.81.0
Time >=10cm from walls, locomotor time 10.50.61.70.8-0.90.60.5-0.60.5-1.00.5-0.3-0.71.3
Bouts of movement, locomotor time 10.10.20.50.3-0.20.30.5-0.20.1-0.60.4-0.2-0.40.7
Total resting periods, locomotor time 10.10.10.20.2-0.20.30.5-0.30.3-0.40.50.1-0.00.5
Rest time, locomotor task time 10.40.51.8-0.30.3-0.3-0.3-0.60.70.70.11.31.3-0.2
Distance moved, locomotor task time 11.11.23.2-0.40.4-0.5-0.81.6-1.7-0.0-1.1-1.8-1.3-0.1
Vertical activity count, locomotor time 10.60.61.9-0.20.3-0.3-0.41.0-1.1-0.1-0.9-1.4-1.1-0.1
Time >=10cm from walls, locomotor time 20.20.20.6-0.20.1-0.2-0.0-0.80.80.2-0.30.6-0.10.5
Bouts of movement, locomotor time 20.60.72.2-0.10.3-0.2-0.51.0-1.2-0.4-0.8-1.1-1.50.6
Total resting periods, locomotor time 20.40.41.40.00.1-0.0-0.30.8-1.0-0.4-0.7-0.9-1.20.5
Rest time, locomotor task time 20.80.93.5-0.1-0.0-0.3-0.4-0.20.31.0-0.31.61.9-1.5
Distance moved, locomotor task time 21.41.65.1-0.60.7-0.5-0.51.8-1.9-0.2-0.7-2.3-1.80.5
Vertical activity count, locomotor time 21.01.12.2-1.21.2-1.2-1.11.1-1.10.7-1.1-1.5-0.6-0.2
Light reinforcement 11.01.94.00.9-0.81.21.1-0.90.7-1.91.7-0.9-2.01.9
Light reinforcement 21.11.44.60.0-0.20.00.0-1.61.70.60.22.12.1-1.0
Bone: marrow area3.16.611.02.8-2.82.82.8-2.72.5-3.32.30.2-1.33.1
Bone: maximum diameter2.44.48.52.0-2.02.02.0-2.92.9-2.21.81.10.42.4
Bone: maximum force1.01.73.31.2-1.21.41.3-1.81.8-1.41.21.00.21.3
Bone: maximum moment1.01.73.81.1-1.11.31.2-1.91.9-1.11.11.50.70.9
Mean time between licks in bursts0.60.81.9-0.80.6-0.9-0.80.5-0.41.1-1.30.11.2-1.4
Mean num. licks in bursts1.31.63.81.3-1.11.51.5-1.41.5-0.80.92.00.80.3
Cd content in liver1.51.63.3-1.31.4-0.9-0.91.6-1.70.4-1.1-1.8-1.5-0.2
Co content in liver0.50.61.9-1.31.4-0.7-0.80.3-0.30.7-0.7-0.2-0.3-0.8
Cu content in liver0.40.51.10.4-0.30.90.9-1.11.0-0.70.40.8-0.40.6
Fe content in liver1.41.64.0-1.21.2-1.4-1.41.3-1.21.0-2.0-1.3-0.2-1.0
K content in liver0.40.41.80.4-0.40.60.5-0.60.5-0.70.40.2-0.21.3
Mg content in liver2.12.16.31.2-1.11.61.5-1.41.3-1.71.60.2-0.82.5
Mn content in liver2.12.37.50.5-0.60.60.6-2.12.20.31.62.72.1-0.3
Na content in liver0.60.61.40.8-0.80.80.8-0.80.7-1.20.60.0-0.41.2
Rb content in liver1.41.73.41.2-1.11.41.4-0.20.0-1.71.7-0.8-1.61.9
Se content in liver1.01.22.7-1.11.0-1.1-1.10.6-0.51.5-1.30.51.2-1.6
Sr content in liver0.60.50.8-0.90.8-0.9-0.90.7-0.70.6-0.4-0.9-0.4-0.6
Zn content in liver0.40.41.1-0.50.5-0.3-0.3-0.70.80.5-0.51.00.8-0.7
Bone: minimum diameter0.71.34.10.3-0.30.50.5-2.02.0-0.30.11.91.40.4
Time in familiar zone, hab. session 10.10.10.3-0.40.3-0.1-0.2-0.50.50.10.4-0.2-0.10.4
Time in novel zone, hab. session 10.20.20.60.1-0.0-0.1-0.10.4-0.40.5-0.80.50.6-0.8
Total zone transitions, hab. session 13.24.510.1-2.02.2-2.2-2.03.1-3.21.4-1.6-2.3-1.2-0.9
Total locomotion distance, hab. session 12.02.98.3-1.31.4-1.6-1.42.8-2.90.9-0.9-2.0-1.3-0.6
Locomotion velocity, hab. session 11.11.54.7-0.80.9-1.0-0.82.1-2.20.4-0.2-1.7-1.3-0.3
Time in familiar zone, hab. session 20.10.10.2-0.30.3-0.3-0.30.1-0.00.50.4-0.20.1-0.2
Time in novel zone, hab. session 20.60.61.20.9-0.90.70.8-0.90.8-0.60.31.10.60.3
Total zone transitions, hab. session 23.24.19.0-1.81.9-1.7-1.72.8-3.00.4-1.5-3.0-2.20.0
Total locomotion distance, hab. session 22.33.16.4-1.61.8-1.5-1.62.4-2.50.5-0.9-2.5-1.9-0.1
Locomotion velocity, hab. session 21.92.55.1-1.61.7-1.4-1.52.1-2.30.5-0.8-2.2-1.6-0.3
Novel to familiar place preference ratio1.31.32.11.1-1.01.31.5-1.21.1-1.41.40.5-0.61.1
Novelty place preference1.81.83.01.2-1.21.51.7-1.61.4-1.51.70.7-0.61.3
Time in novel zone, NPP test2.52.64.01.6-1.51.81.9-1.91.8-1.72.01.0-0.31.4
Total zone transitions, NPP test1.62.24.8-1.31.4-1.5-1.52.1-2.20.4-0.9-2.1-1.3-0.1
Total locomotion distance, NPP test1.82.56.3-1.31.4-1.4-1.52.2-2.30.3-0.6-2.5-1.60.0
Locomotion velocity, NPP test2.83.98.5-1.71.8-1.9-1.92.8-2.90.6-1.0-2.9-1.8-0.3
Intraocular pressure0.30.41.0-0.60.6-0.5-0.61.0-1.00.6-0.2-0.4-0.1-0.9
Delta distance traveled before/after self-admin1.82.03.51.4-1.41.51.4-1.91.9-1.41.31.40.60.9
Delta ambulatory time before/after self-admin1.92.14.61.4-1.41.31.3-2.12.1-1.01.21.71.20.6
Parametrial fat weight1.12.23.9-1.61.7-1.5-1.62.0-1.91.2-1.6-1.3-0.2-0.6
Pavlov. Cond. lever latency1.01.34.51.4-1.30.91.0-0.50.60.00.52.11.8-0.5
Pavlov. Cond. magazine entry latency2.22.88.0-2.82.8-1.9-2.00.7-0.61.5-1.4-1.1-0.9-0.9
Pavlov. Cond. change in total contacts0.60.61.9-1.41.3-0.6-0.80.1-0.10.3-0.2-0.9-1.1-0.3
Pavlov. Cond. index score2.22.76.6-2.62.5-1.8-1.90.9-0.91.0-1.3-2.0-1.5-0.3
Pavlov. Cond. latency score2.12.65.9-2.42.4-1.8-1.91.0-1.00.9-1.2-2.0-1.5-0.3
Pavlov. Cond. lever contacts0.80.92.6-1.41.3-0.8-0.90.3-0.40.1-0.6-1.6-1.40.2
Pavlov. Cond. magazine entry number2.32.97.62.8-2.71.92.0-1.01.0-1.51.41.31.01.0
Pavlov. Cond. intertrial magazine entries0.91.14.00.00.1-0.4-0.41.7-1.8-0.4-0.1-2.0-1.10.7
Pavlov. Cond. lever-magazine prob. diff.1.92.45.6-2.42.3-1.5-1.70.7-0.80.7-1.2-1.9-1.70.0
Pavlov. Cond. response bias1.41.74.5-2.12.1-1.2-1.30.6-0.60.7-1.1-1.4-1.3-0.2
Pavlov. Cond. lever latency0.50.61.61.3-1.20.90.90.3-0.4-0.71.10.4-0.30.1
Pavlov. Cond. magazine entry latency3.64.17.3-2.52.3-2.4-2.51.0-0.72.7-2.40.31.5-2.3
Pavlov. Cond. change in total contacts1.01.33.0-1.71.7-1.4-1.40.3-0.11.3-1.3-0.30.6-0.9
Pavlov. Cond. index score1.62.03.8-1.91.9-1.8-1.80.4-0.21.6-1.9-0.40.7-1.0
Pavlov. Cond. latency score1.11.42.9-1.61.5-1.5-1.50.10.11.4-1.7-0.10.9-0.9
Pavlov. Cond. lever contacts0.30.41.1-1.01.0-0.7-0.7-0.60.80.4-0.7-0.30.20.1
Pavlov. Cond. magazine entry number2.63.25.22.2-2.12.22.3-1.00.8-2.22.30.3-1.11.7
Pavlov. Cond. intertrial magazine entries0.70.92.61.1-1.10.91.1-0.60.4-1.21.6-0.1-0.21.0
Pavlov. Cond. lever-magazine prob. diff.1.82.34.4-2.12.0-1.9-1.90.4-0.21.8-2.0-0.30.8-1.1
Pavlov. Cond. response bias1.31.84.0-2.02.0-1.6-1.70.4-0.21.4-1.6-0.50.4-0.9
Time in closed arm before self-admin0.00.00.1-0.30.3-0.2-0.1-0.10.10.1-0.2-0.3-0.3-0.1
Time in closed arm after self-admin0.20.21.6-0.30.2-0.1-0.1-0.20.10.40.00.70.3-1.3
Time in open arm before self-admin2.83.05.01.7-1.71.81.8-2.12.1-1.72.21.00.31.8
Time in open arm after self-admin0.40.51.01.0-1.00.50.5-0.50.6-0.40.70.71.00.7
Bone: periosteal estimation2.24.57.42.2-2.22.22.2-2.72.6-2.41.71.1-0.02.3
Bone: periosteal perimeter1.72.94.01.8-1.81.91.8-2.01.9-1.91.50.9-0.01.9
Bone: post-yield work0.40.62.00.2-0.20.00.0-0.50.4-0.90.8-1.1-0.91.4
Progressive ratio test 1 active lever presses0.50.51.60.7-0.70.60.5-0.80.9-0.10.11.30.7-0.2
Progressive ratio test 1 breakpoint0.50.51.80.6-0.60.50.3-0.91.00.1-0.01.30.8-0.1
Progressive ratio test 1 inactive lever presses0.50.52.20.1-0.2-0.00.1-0.60.70.6-0.21.31.5-0.8
Progressive ratio test 2 active lever presses0.30.30.60.8-0.80.80.8-0.20.1-0.60.50.2-0.50.0
Progressive ratio test 2 breakpoint0.30.30.80.9-0.90.80.8-0.20.1-0.60.50.2-0.30.0
Progressive ratio test 2 inactive lever presses0.91.04.1-0.50.4-0.5-0.4-0.10.31.1-0.61.32.0-1.7
Incentive Sensitization - Responses0.70.71.70.8-0.81.01.1-0.20.1-1.01.3-0.3-1.20.5
Incentive Sensitization - Breakpoint0.50.51.80.5-0.50.70.90.1-0.3-0.81.0-0.6-1.30.3
Sum of active levers in priming session hrs 5-60.60.61.31.1-1.10.90.9-0.60.6-0.70.80.50.30.4
Progressive ratio0.10.10.2-0.50.4-0.0-0.1-0.40.3-0.10.4-0.1-0.40.4
Food seeking constrained by brief footshock0.70.82.70.6-0.60.3-0.1-0.30.2-1.10.4-1.3-1.51.6
Seeking ratio, punishment vs. effort0.70.91.81.3-1.20.90.8-0.0-0.1-1.20.3-0.8-1.11.2
Retroperitoneal fat weight0.61.94.0-1.72.0-1.4-1.11.6-1.60.9-1.8-0.9-0.7-0.5
Reaction time number correct0.30.51.20.8-0.80.30.30.6-0.7-0.80.7-0.9-1.10.3
Reaction time mean minus median0.20.21.0-0.40.4-0.3-0.3-0.10.20.7-0.21.00.6-0.4
Reaction time mean minus median AUC0.50.71.3-0.70.8-0.8-0.80.10.01.1-0.90.91.1-0.8
Reaction time num false alarms0.50.71.9-0.40.4-0.7-0.81.1-1.10.8-1.4-0.10.5-1.1
Reaction time num false alarms AUC0.30.41.2-0.00.0-0.4-0.51.0-1.00.5-1.1-0.20.4-0.9
Reaction time trials correct on left0.30.51.20.8-0.80.30.30.6-0.7-0.80.7-0.9-1.10.3
Reaction time trials on left0.40.51.20.7-0.70.20.30.7-0.8-0.80.7-0.9-1.10.2
Reaction time mean1.11.52.8-1.31.3-1.2-1.3-0.10.31.7-1.11.31.6-1.4
Reaction time mean AUC0.70.91.7-1.11.1-1.0-1.1-0.10.21.3-0.91.01.2-0.9
Median of all reaction times1.41.93.5-1.51.5-1.4-1.50.10.21.9-1.31.21.7-1.7
Reaction time omissions0.30.41.70.1-0.0-0.2-0.21.2-1.3-0.10.7-0.7-0.6-0.1
Reaction time false alarm rate0.50.82.2-0.60.6-0.7-0.80.7-0.61.0-1.50.31.0-1.1
Reaction time premature initiation rate0.20.20.40.5-0.50.60.4-0.70.6-0.60.10.50.00.3
Reaction time premature initiations0.30.41.00.9-0.90.80.6-0.40.3-1.00.60.1-0.50.5
Std. dev. reaction times0.81.12.2-1.21.2-1.1-1.10.4-0.21.5-1.00.91.0-1.1
Reaction time trials completed0.40.51.20.7-0.70.20.30.7-0.8-0.80.7-0.9-1.10.2
Reaction time trials AUC0.30.51.10.7-0.70.20.30.6-0.8-0.80.7-0.9-1.00.2
Run reversals in cocaine runway, females0.20.21.10.0-0.0-0.3-0.3-0.00.10.5-0.00.81.0-0.7
Run reversals in cocaine runway, males1.01.04.1-0.30.4-0.3-0.20.9-1.0-0.50.2-2.0-1.81.1
Latency to leave start box in cocaine runway1.21.32.81.3-1.31.41.7-1.00.9-1.31.30.1-0.80.6
Latency to leave start box in cocaine runway, F0.20.31.00.4-0.40.50.7-0.20.1-0.60.4-0.6-1.00.3
Latency to leave start box in cocaine runway, M1.01.02.21.1-1.11.41.5-0.80.7-1.01.10.3-0.70.6
Std. dev. time between licks in bursts0.20.21.3-0.30.2-0.3-0.20.2-0.3-0.2-0.1-1.2-0.40.4
Total sessions with >9 infusions0.91.02.01.2-1.31.00.8-1.01.1-0.30.51.41.0-0.5
Short access day 1 total inactive lever presses1.21.33.80.8-0.90.91.0-1.41.5-0.40.71.51.9-0.3
Short access day 10 total inactive lever presses0.40.43.0-0.50.4-0.4-0.3-0.20.30.6-0.20.61.7-0.2
Short access day 1 total infusions0.40.41.40.1-0.10.10.0-0.60.70.4-0.11.21.1-0.8
Short access day 10 total infusions0.70.82.80.3-0.30.1-0.0-0.70.90.8-0.81.71.5-0.9
Short access total infusions0.91.03.5-0.0-0.0-0.2-0.3-0.30.51.0-0.91.71.9-1.5
Short access day 1 locomotion0.30.30.60.5-0.50.60.4-0.80.8-0.40.30.70.20.1
Short access day 10 total locomotion1.11.32.60.8-0.80.91.0-1.51.5-0.51.01.51.60.4
Short access total locomotion1.21.24.30.1-0.10.20.2-1.31.50.60.12.12.1-0.8
One hour access (0.3 mA shock)0.10.10.50.4-0.40.60.5-0.20.2-0.10.20.70.00.0
Compulsive drug intake1.11.12.01.1-1.21.01.0-1.21.3-0.11.41.40.50.1
One hour access (shock baseline)0.10.10.6-0.20.3-0.1-0.1-0.10.20.1-0.70.30.4-0.2
Social response proportion1.71.85.61.3-1.31.41.5-1.61.6-0.40.72.40.9-0.5
Social responses0.10.20.4-0.20.1-0.2-0.3-0.60.70.3-0.00.70.1-0.6
Social time0.40.51.00.9-0.90.81.0-0.50.5-0.70.80.50.10.5
Soleus weight9.928.953.35.9-5.86.46.3-3.83.1-7.35.2-1.3-5.06.2
Bone: stiffness0.91.43.21.5-1.41.21.3-0.40.2-1.71.8-0.2-0.71.3
Tibialis anterior weight9.934.053.77.3-7.37.27.1-4.33.7-7.26.30.4-3.35.5
Time to tail flick, vehicle, before self-admin1.61.73.6-1.01.1-1.2-1.21.5-1.50.6-1.3-1.9-1.80.1
Time to tail flick, vehicle, after self-admin2.32.54.42.0-2.11.51.5-1.81.8-1.31.61.21.10.8
Time to tail flick, test, before self-admin1.81.73.1-1.71.8-1.5-1.41.2-1.21.1-1.0-1.0-1.1-1.1
Time to tail flick, test, after self-admin1.11.12.4-1.41.2-1.5-1.50.9-0.81.0-0.6-1.30.2-0.4
Delta time to tail flick, vehicle, before/after SA2.62.63.71.8-1.91.51.6-1.81.8-1.41.81.41.60.7
Delta time to tail flick, test, before/after SA0.70.71.30.8-1.00.60.5-1.11.1-0.50.80.51.20.5
Tibia length1.33.711.70.8-0.91.31.2-3.33.4-0.81.32.51.61.8
Ambulatory time before self-admin0.20.20.70.4-0.50.60.5-0.20.1-0.50.8-0.2-0.20.1
Ambulatory time after self-admin3.53.95.82.2-2.32.12.1-2.42.4-1.92.11.50.81.3
Bone: tissue strength0.40.41.3-0.30.3-0.4-0.30.3-0.10.90.00.81.1-1.2
Total heroin consumption1.11.32.71.2-1.11.01.1-0.30.2-1.41.2-1.0-1.41.7
Bone: trabecular number1.01.52.6-1.41.4-1.6-1.61.0-0.91.1-1.5-0.90.3-1.0
Bone: trabecular spacing0.30.30.9-0.60.7-0.3-0.30.9-0.90.7-0.7-0.1-0.2-0.3
Bone: trabecular thickness0.81.03.40.2-0.20.10.0-1.31.40.30.01.81.8-0.7
Bone: trabecular tissue density5.98.313.83.5-3.43.63.7-2.72.5-2.73.12.60.51.7
Water consumed over 24 hours0.40.52.1-0.20.1-0.2-0.1-1.31.40.1-0.50.61.10.1
Number of responses in last shaping day1.41.55.60.1-0.30.50.5-2.22.4-0.00.61.71.50.0