Hub : Genes

Uqcc3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Uqcc3 0.02 0.02 9.0e-03 0.02 0.01 0.01 0.01 6.2e-03 2.9e-02 6.9e-02 2.9e-02
2 PL gene expression Uqcc3 0.07 0.04 9.8e-12 0.1 0.11 0.1 0.1 2.8e-11 1.1e-11 4.1e-11 2.4e-11
3 pVTA gene expression Uqcc3 0.08 0.05 2.8e-04 0.07 0.06 0.03 0.05 8.4e-04 2.1e-03 1.5e-02 4.1e-03
4 Brain gene expression Uqcc3 0.06 0.03 1.5e-06 0.06 0.06 0.05 0.06 1.9e-06 1.6e-06 8.8e-06 2.6e-06
5 BLA gene expression Uqcc3 0.06 0.04 8.4e-04 0.04 0.05 0.04 0.04 2.6e-03 9.9e-04 4.3e-03 3.1e-03
6 OFC gene expression Uqcc3 0.14 0.09 3.4e-03 0.09 0.07 0.06 0.07 4.4e-03 9.0e-03 1.4e-02 1.1e-02
7 NAcc gene expression Uqcc3 0.05 0.03 3.3e-07 0.06 0.06 0.06 0.06 5.0e-08 1.1e-07 6.8e-08 6.2e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density0.20.40.70.60.5-0.60.50.8-0.6-0.6
Area under the delay curve0.00.00.1-0.10.0-0.00.10.3-0.3-0.3
BMI with tail2.06.510.72.52.3-2.42.43.3-2.4-2.4
BMI without tail1.02.12.91.31.3-1.31.51.7-1.5-1.5
Body weight3.614.917.73.73.8-3.73.94.2-4.0-3.7
Weight adjusted by age1.51.72.11.31.4-1.31.21.5-1.0-1.3
Bone surface1.52.73.91.81.7-1.81.42.0-1.4-1.3
Bone volume0.50.91.61.11.0-1.10.71.3-0.7-0.7
Breakpoint value in progressive ratio session1.92.12.71.61.7-1.61.51.3-1.1-1.1
Number of licking bursts0.00.00.10.3-0.10.2-0.1-0.00.10.1
Context. condit. distance diff. score0.20.20.5-0.5-0.70.5-0.5-0.40.10.2
Locomotion velocity, session 10.10.10.30.20.0-0.10.30.2-0.5-0.5
Locomotion distance, session 10.70.91.40.90.7-0.90.91.0-1.2-1.1
Locomotion velocity, session 22.93.44.02.01.8-2.01.81.9-1.8-1.6
Locomotion distance, session 20.30.40.70.60.5-0.60.70.6-0.9-0.7
Locomotion velocity, session 30.30.30.70.50.3-0.50.50.9-0.7-0.5
Locomotion distance, session 30.10.10.20.10.1-0.10.30.2-0.5-0.3
Stereotopy head waving bouts, day 30.10.10.2-0.1-0.50.1-0.40.2-0.20.4
Stereotopy head waving duration, day 30.10.10.2-0.2-0.50.2-0.30.0-0.20.3
Locomotion velocity, session 70.00.00.1-0.0-0.20.0-0.20.1-0.10.3
Locomotion distance, session 70.00.10.1-0.3-0.40.3-0.2-0.1-0.1-0.0
Stereotopy head waving bouts, day 70.10.10.20.50.3-0.50.10.5-0.40.2
Stereotopy head waving duration, day 71.92.32.71.61.5-1.61.41.6-1.5-1.2
Locomotion velocity, session 80.00.00.10.0-0.1-0.00.2-0.1-0.4-0.3
Locomotion distance, session 80.10.20.4-0.4-0.60.4-0.5-0.2-0.00.3
Degree of sensitization distance0.10.10.1-0.2-0.40.3-0.30.20.10.1
Degree of sensitization stereotypy0.80.91.41.21.0-1.20.81.1-0.8-0.5
Conditioned locomotion0.70.81.10.90.9-0.80.90.9-1.0-0.9
Cocaine response after cond. corrected0.50.61.8-1.3-0.90.8-0.6-0.70.30.3
Cocaine response after cond. not corrected0.40.51.1-1.1-0.80.6-0.6-0.60.60.3
Cocaine response before conditioning0.40.42.01.40.6-0.70.30.40.3-0.1
Saline control response2.43.14.40.41.9-1.82.01.7-2.1-1.9
Bone: connectivity density1.62.53.41.71.5-1.71.51.8-1.3-1.6
Bone: cortical apparent density0.60.81.01.00.9-0.90.90.6-1.0-0.8
Bone: cortical area0.71.11.31.11.0-1.10.91.2-1.1-0.7
Bone: cortical porosity0.00.00.1-0.1-0.10.1-0.1-0.3-0.00.4
Bone: cortical porosity0.10.10.20.20.3-0.20.30.0-0.4-0.1
Bone: cortical thickness3.35.56.42.32.4-2.32.52.0-2.5-2.3
Bone: cortical thickness0.70.81.10.80.8-0.81.00.6-1.1-1.0
Bone: cortical tissue density0.71.01.21.11.0-1.01.00.7-1.1-0.9
Condit. Reinf. active minus inactive responses1.11.21.41.21.1-1.21.11.1-1.0-1.1
Condit. Reinf. active-inactive response ratio0.50.50.80.70.8-0.70.80.6-0.7-0.9
Condit. Reinf. active responses0.81.01.41.21.0-1.20.81.2-0.8-0.7
Condit. Reinf. inactive responses0.10.10.3-0.0-0.20.0-0.40.20.50.5
Incentive salience index mean1.31.61.91.31.2-1.31.21.4-1.2-1.3
Condit. Reinf. lever presses0.70.91.31.00.9-1.00.81.1-0.9-0.9
Condit. Reinf. active minus inactive responses0.50.61.2-0.4-0.60.5-0.8-0.71.01.1
Condit. Reinf. active-inactive response ratio1.11.22.6-0.7-0.90.7-1.2-0.61.41.6
Condit. Reinf. active responses0.00.00.20.40.00.0-0.1-0.10.00.2
Condit. Reinf. inactive responses0.30.40.80.70.4-0.20.60.1-0.9-0.9
Condit. Reinf. lever presses0.81.13.31.81.0-1.00.81.0-0.6-0.7
Condit. Reinf. lever reinforcers received0.10.10.50.70.3-0.30.20.2-0.2-0.0
Conditioned reinforcement - actives2.62.63.3-1.6-1.51.3-1.7-1.51.81.8
Conditioned reinforcement - inactives1.01.11.7-0.6-1.10.9-1.3-0.81.31.2
Conditioned locomotion2.02.33.1-1.2-1.71.5-1.8-1.31.61.6
Patch foraging indifference point 0 sec0.71.12.81.71.0-0.91.01.0-0.9-0.8
Patch foraging indifference point AUC1.82.13.51.31.7-1.91.41.6-1.1-1.0
Delay disc. indifference point, 0s delay0.20.20.5-0.7-0.60.6-0.3-0.10.00.0
Delay disc. indifference point, 16s delay0.10.10.20.00.2-0.30.10.5-0.1-0.2
Delay disc. indifference point, 2s delay0.20.20.3-0.5-0.60.5-0.5-0.20.50.4
Delay disc. indifference point, 24s delay0.20.20.40.10.3-0.20.50.3-0.6-0.6
Delay disc. indifference point, 4s delay0.50.51.00.30.5-0.40.70.7-1.0-1.0
Delay disc. indifference point, 8s delay0.20.20.5-0.6-0.60.7-0.3-0.50.10.2
Indifference point function ln k2.63.65.8-1.8-2.42.4-1.8-2.01.31.2
Indifference point function log k2.63.65.8-1.8-2.42.4-1.8-2.01.31.2
Patch foraging total patch changes 0 sec0.71.12.01.41.0-0.91.10.9-1.0-1.0
Patch foraging total patch changes 12 sec6.88.810.93.33.2-3.23.02.9-2.7-2.3
Patch foraging total patch changes 18 sec0.40.51.00.40.9-1.00.80.7-0.7-0.5
Patch foraging total patch changes 24 sec7.38.910.22.13.2-3.13.13.2-3.2-2.9
Patch foraging total patch changes 6 sec1.32.02.71.61.4-1.41.41.4-1.3-1.2
Patch foraging time to switch 0 sec0.30.51.11.00.6-0.80.41.0-0.5-0.3
Patch foraging water rate 0 sec0.30.51.0-0.2-0.80.9-0.6-1.00.50.4
Patch foraging water rate 12 sec1.42.23.6-1.9-1.61.9-1.2-1.70.80.6
Patch foraging water rate 18 sec0.50.71.5-1.1-0.91.2-0.5-0.80.2-0.2
Patch foraging water rate 24 sec1.01.32.1-1.0-1.31.4-1.1-1.40.90.7
Patch foraging water rate 6 sec1.01.52.9-1.7-1.31.5-0.9-1.40.60.5
Seeking ratio, delayed vs. immediate footshock0.10.10.20.50.1-0.00.10.1-0.1-0.4
Distance traveled before self-admin2.22.32.91.71.6-1.71.41.5-1.4-1.3
Distance traveled after self-admin0.20.20.40.40.6-0.50.40.4-0.3-0.4
Extensor digitorum longus weight6.726.528.65.15.2-5.15.25.4-5.2-5.0
Bone: elastic displacement0.40.40.8-0.8-0.60.8-0.4-0.90.30.2
Bone: elastic work1.01.42.31.01.1-0.91.30.9-1.5-1.4
Bone: endosteal estimation1.32.83.9-1.6-1.81.6-2.0-1.01.71.8
Bone: endosteal perimeter2.24.56.5-1.9-2.21.9-2.5-1.42.12.5
Epididymis fat weight0.41.01.4-1.1-1.11.2-1.1-0.61.01.0
Delta time in closed arm before/after self-admin2.12.13.31.01.2-1.11.61.3-1.7-1.8
Delta time in open arm before/after self-admin1.51.42.41.51.3-1.51.01.2-0.9-0.6
Diff in mean of infusions in LGA sessions1.92.12.61.51.6-1.51.61.2-1.4-1.2
Delay discount exponential model param0.00.00.10.1-0.00.0-0.1-0.30.30.3
Extinction: sum of active levers before priming4.04.04.72.02.1-2.22.02.0-2.0-1.8
Active lever presses in extinction session 62.62.63.71.91.8-1.91.51.5-1.3-1.2
Bone: final force2.03.24.01.91.7-1.91.62.0-1.8-1.6
Bone: final moment1.93.13.81.81.7-1.81.61.9-1.8-1.6
Food consumed during 24 hour testing period0.20.30.7-0.8-0.30.5-0.4-0.40.70.4
Glucose3.35.05.9-2.3-2.32.3-2.3-1.92.42.1
Heart weight0.91.22.1-1.4-1.21.4-1.0-0.90.90.8
Delay discount hyperbolic model param0.00.00.10.0-0.00.0-0.2-0.30.30.3
Intermittent access intake day 1-15 change1.71.62.5-1.0-1.01.0-1.3-1.31.61.6
Intermittent access intake escalation1.01.01.6-0.6-0.80.7-1.0-1.11.31.3
Intermittent access intake escalation 20.10.10.30.30.0-0.1-0.2-0.20.40.5
Intermitt. access day 1 inactive lever presses1.92.02.6-1.1-1.61.3-1.6-1.31.41.5
Intermitt. access day 15 inactive lever presses0.10.10.30.50.0-0.3-0.20.40.20.0
Intermitt. access escalation Index0.10.10.3-0.3-0.50.6-0.2-0.30.10.1
Intermittent access day 1 total infusions0.70.91.5-0.7-1.20.8-1.2-0.31.00.9
Intermittent access day 15 total infusions3.64.15.5-1.6-2.11.8-2.3-1.62.32.2
Intermittent access terminal intake (last 3 days)0.70.81.5-0.3-0.90.5-1.2-0.31.21.2
Intermittent access total infusions1.01.11.8-0.6-1.20.8-1.3-0.51.31.2
Intermittent access day 1 locomotion0.10.10.3-0.1-0.60.2-0.40.40.20.2
Intermittent access day 15 total locomotion0.20.20.4-0.1-0.50.1-0.60.00.60.6
Intermittent access total locomotion0.20.20.5-0.1-0.5-0.0-0.70.50.50.5
Intermittent access standard deviation1.51.62.4-1.0-1.11.0-1.3-1.31.51.5
Left kidney weight0.00.00.20.00.1-0.0-0.00.40.20.3
Right kidney weight0.10.20.50.40.4-0.40.20.7-0.10.1
Cocaine induced anxiety0.40.41.61.30.5-0.50.40.5-0.3-0.3
Post-drug Anxiety0.70.82.21.50.9-0.90.60.8-0.6-0.6
Baseline Anxiety1.11.11.50.41.2-1.11.21.0-1.2-1.2
Tail length1.03.04.01.51.9-1.62.01.4-1.9-1.7
Length with tail2.48.69.62.83.1-2.93.12.9-3.0-2.8
Length without tail1.94.14.52.02.1-2.02.02.1-2.1-1.8
Times rat made contact with spout0.20.20.50.30.4-0.20.60.2-0.7-0.7
Lifetime Intake0.80.91.4-0.5-1.20.8-1.2-0.51.21.1
Liver weight, left0.30.50.7-0.8-0.70.8-0.6-0.80.60.5
Liver weight, right0.00.00.1-0.2-0.10.1-0.00.1-0.2-0.3
Locomotor activity0.50.71.9-0.5-1.01.4-0.6-1.20.40.2
Locomotor testing distance0.50.82.0-0.6-1.11.4-0.6-1.20.30.1
Locomotor testing rearing0.81.22.2-1.1-1.21.5-0.9-1.30.80.6
Locomotion in novel chamber2.63.24.5-1.7-1.81.7-2.0-1.42.11.8
Locomotion in novel chamber post-restriction2.73.34.1-2.0-1.81.8-1.8-1.71.61.9
Fecal boli incidents, locomotor time 10.50.61.1-0.8-0.50.3-0.8-0.51.01.0
Change in fecal boli incidents, locomotor task0.40.40.8-0.5-0.80.9-0.5-0.60.10.1
Time >=10cm from walls, locomotor time 12.82.93.7-1.8-1.71.4-1.9-1.31.81.9
Bouts of movement, locomotor time 10.10.10.30.30.6-0.40.4-0.1-0.1-0.1
Total resting periods, locomotor time 10.10.10.30.30.6-0.50.40.0-0.0-0.0
Rest time, locomotor task time 11.41.62.0-1.3-1.21.3-1.2-1.41.21.3
Distance moved, locomotor task time 10.30.30.50.70.5-0.50.50.7-0.5-0.6
Vertical activity count, locomotor time 10.60.60.7-0.6-0.90.8-0.8-0.80.70.7
Time >=10cm from walls, locomotor time 20.30.30.5-0.5-0.30.2-0.5-0.40.70.7
Bouts of movement, locomotor time 21.41.51.71.21.3-1.21.31.1-1.2-1.1
Total resting periods, locomotor time 20.70.70.80.90.9-0.90.90.8-0.8-0.7
Rest time, locomotor task time 23.54.04.4-2.0-2.12.1-2.0-2.01.91.9
Distance moved, locomotor task time 20.50.61.01.00.9-0.80.80.6-0.6-0.7
Vertical activity count, locomotor time 20.00.00.10.00.10.10.2-0.3-0.2-0.3
Light reinforcement 10.10.10.30.0-0.30.4-0.3-0.60.20.4
Light reinforcement 20.50.61.7-0.7-0.50.3-0.9-0.30.91.3
Bone: marrow area1.53.24.4-1.7-2.01.7-2.1-1.11.71.9
Bone: maximum diameter0.10.10.40.50.2-0.5-0.00.6-0.30.3
Bone: maximum force2.33.96.12.11.9-2.11.72.5-1.8-1.6
Bone: maximum moment2.13.65.62.01.9-2.01.62.4-1.7-1.6
Mean time between licks in bursts0.81.13.2-0.00.9-0.61.30.9-1.1-1.8
Mean num. licks in bursts0.00.10.2-0.5-0.00.10.1-0.2-0.2-0.2
Cd content in liver1.71.94.8-2.2-1.21.1-1.3-1.11.01.2
Co content in liver1.51.73.4-1.3-1.31.5-1.1-1.90.90.8
Cu content in liver0.30.40.70.50.5-0.40.70.4-0.7-0.8
Fe content in liver0.00.00.10.2-0.0-0.1-0.10.00.00.3
K content in liver1.31.34.12.00.9-0.90.81.2-0.8-0.7
Mg content in liver0.50.51.81.30.4-0.50.40.9-0.5-0.4
Mn content in liver2.73.08.52.91.6-1.51.51.6-1.2-1.3
Na content in liver0.60.61.31.10.8-0.90.60.9-0.8-0.3
Rb content in liver1.51.82.9-1.7-1.51.5-1.3-1.31.01.1
Se content in liver0.40.52.71.60.4-0.40.10.60.10.2
Sr content in liver5.75.26.12.02.5-2.42.42.3-2.3-2.1
Zn content in liver4.14.55.82.02.2-2.42.12.3-2.0-1.8
Bone: minimum diameter0.71.32.1-1.1-1.31.1-1.4-0.51.01.3
Time in familiar zone, hab. session 10.10.10.20.20.2-0.20.20.3-0.0-0.5
Time in novel zone, hab. session 11.31.31.7-1.2-1.21.2-1.0-1.30.90.9
Total zone transitions, hab. session 10.30.51.10.70.6-0.60.70.6-1.1-0.5
Total locomotion distance, hab. session 10.10.10.2-0.1-0.30.1-0.40.00.00.5
Locomotion velocity, hab. session 10.10.20.30.50.3-0.50.20.5-0.5-0.0
Time in familiar zone, hab. session 20.40.40.7-0.8-0.50.8-0.4-0.90.5-0.1
Time in novel zone, hab. session 20.60.61.00.90.6-0.80.61.0-0.7-0.4
Total zone transitions, hab. session 21.72.12.91.41.3-1.41.41.5-1.5-1.7
Total locomotion distance, hab. session 20.10.20.30.40.3-0.40.30.5-0.3-0.5
Locomotion velocity, hab. session 20.00.10.20.30.1-0.30.10.4-0.1-0.1
Novel to familiar place preference ratio1.92.02.61.51.5-1.51.41.6-1.3-1.0
Novelty place preference1.01.11.61.11.1-1.11.01.3-0.8-0.6
Time in novel zone, NPP test1.21.21.71.11.2-1.11.11.3-1.0-0.7
Total zone transitions, NPP test1.52.12.51.51.3-1.51.41.4-1.6-1.5
Total locomotion distance, NPP test0.10.20.20.50.2-0.50.40.4-0.5-0.3
Locomotion velocity, NPP test0.10.10.10.40.1-0.40.20.3-0.4-0.1
Intraocular pressure0.10.20.4-0.5-0.20.4-0.3-0.50.60.4
Delta distance traveled before/after self-admin0.60.61.0-1.0-0.81.0-0.6-0.90.60.5
Delta ambulatory time before/after self-admin1.01.11.6-1.2-1.01.3-0.8-1.20.80.7
Parametrial fat weight1.63.14.0-1.7-1.91.8-2.0-1.41.71.9
Pavlov. Cond. lever latency1.11.42.0-1.3-1.11.3-1.0-1.40.91.1
Pavlov. Cond. magazine entry latency0.81.01.61.21.1-1.20.81.3-0.6-0.7
Pavlov. Cond. change in total contacts0.20.20.50.60.4-0.70.10.60.20.0
Pavlov. Cond. index score0.50.60.90.90.8-1.00.60.9-0.4-0.5
Pavlov. Cond. latency score0.40.50.70.80.7-0.90.60.8-0.4-0.6
Pavlov. Cond. lever contacts0.20.20.40.50.4-0.50.40.6-0.3-0.4
Pavlov. Cond. magazine entry number0.50.61.1-1.0-0.91.1-0.6-0.80.30.4
Pavlov. Cond. intertrial magazine entries0.00.00.10.30.2-0.30.10.00.20.3
Pavlov. Cond. lever-magazine prob. diff.0.60.71.11.00.9-1.10.71.0-0.5-0.6
Pavlov. Cond. response bias0.50.61.01.00.9-1.00.60.9-0.3-0.6
Pavlov. Cond. lever latency0.60.83.4-1.8-0.70.7-0.5-0.80.40.6
Pavlov. Cond. magazine entry latency4.65.39.03.02.4-2.52.22.2-1.4-2.1
Pavlov. Cond. change in total contacts1.11.52.61.61.3-1.41.01.3-0.6-0.8
Pavlov. Cond. index score2.63.37.62.81.8-2.01.61.8-1.0-1.4
Pavlov. Cond. latency score2.53.18.02.81.7-1.91.41.7-0.9-1.3
Pavlov. Cond. lever contacts0.70.94.52.10.7-0.70.50.6-0.2-0.5
Pavlov. Cond. magazine entry number6.88.310.5-3.2-3.13.2-2.8-3.02.12.6
Pavlov. Cond. intertrial magazine entries1.92.54.0-2.0-1.51.5-1.5-1.61.21.7
Pavlov. Cond. lever-magazine prob. diff.2.93.67.02.72.0-2.11.71.9-1.1-1.6
Pavlov. Cond. response bias1.72.25.32.31.5-1.51.31.4-0.8-1.2
Time in closed arm before self-admin0.10.10.3-0.1-0.10.2-0.4-0.10.50.5
Time in closed arm after self-admin0.50.51.0-0.9-0.81.0-0.6-0.70.60.5
Time in open arm before self-admin0.60.61.2-1.1-0.91.1-0.4-1.00.20.1
Time in open arm after self-admin0.10.10.20.30.3-0.30.3-0.0-0.4-0.2
Bone: periosteal estimation0.10.20.5-0.2-0.40.2-0.60.20.30.7
Bone: periosteal perimeter0.10.10.5-0.1-0.30.1-0.50.10.20.7
Bone: post-yield work0.50.61.4-0.4-0.70.4-1.10.11.21.0
Progressive ratio test 1 active lever presses2.12.12.6-1.3-1.51.3-1.6-1.31.61.6
Progressive ratio test 1 breakpoint2.42.53.0-1.4-1.61.4-1.7-1.41.71.7
Progressive ratio test 1 inactive lever presses0.10.10.20.30.1-0.30.30.4-0.2-0.3
Progressive ratio test 2 active lever presses1.92.02.9-1.3-1.51.1-1.6-1.11.71.6
Progressive ratio test 2 breakpoint3.13.44.5-1.8-1.81.6-2.0-1.52.12.0
Progressive ratio test 2 inactive lever presses0.70.81.6-0.4-1.00.6-1.1-0.41.31.1
Incentive Sensitization - Responses0.10.10.20.10.2-0.40.00.50.1-0.0
Incentive Sensitization - Breakpoint0.00.00.10.00.1-0.2-0.10.40.20.1
Sum of active levers in priming session hrs 5-60.80.81.71.21.2-1.30.70.8-0.4-0.2
Progressive ratio0.00.00.1-0.3-0.0-0.0-0.20.10.0-0.1
Food seeking constrained by brief footshock0.10.10.3-0.5-0.30.3-0.1-0.3-0.1-0.1
Seeking ratio, punishment vs. effort0.00.00.1-0.1-0.10.30.1-0.2-0.2-0.1
Retroperitoneal fat weight2.68.510.2-3.1-3.23.2-3.0-2.52.72.7
Reaction time number correct0.50.71.4-0.40.9-0.61.00.7-1.0-1.2
Reaction time mean minus median0.10.20.40.30.7-0.60.30.40.10.2
Reaction time mean minus median AUC0.00.10.2-0.20.4-0.30.20.00.10.1
Reaction time num false alarms0.10.10.30.2-0.40.5-0.0-0.60.1-0.2
Reaction time num false alarms AUC0.20.20.60.80.20.00.6-0.1-0.5-0.7
Reaction time trials correct on left0.50.71.4-0.40.9-0.61.00.7-1.0-1.2
Reaction time trials on left0.50.81.4-0.40.9-0.71.00.7-1.0-1.2
Reaction time mean0.10.20.5-0.1-0.1-0.1-0.4-0.30.70.6
Reaction time mean AUC0.20.30.8-0.2-0.20.1-0.5-0.50.90.7
Median of all reaction times0.00.00.10.10.1-0.3-0.10.00.40.2
Reaction time omissions0.10.10.20.00.4-0.30.4-0.0-0.2-0.2
Reaction time false alarm rate0.10.20.70.8-0.40.4-0.1-0.50.20.1
Reaction time premature initiation rate4.15.47.01.32.3-2.22.52.4-2.6-2.6
Reaction time premature initiations5.17.29.91.22.8-2.53.02.6-3.0-3.1
Std. dev. reaction times0.20.20.6-0.0-0.10.1-0.4-0.50.80.8
Reaction time trials completed0.50.81.4-0.40.9-0.71.00.7-1.0-1.2
Reaction time trials AUC0.40.61.2-0.50.8-0.50.90.6-0.9-1.1
Run reversals in cocaine runway, females1.21.22.10.80.7-0.91.11.1-1.5-1.4
Run reversals in cocaine runway, males0.50.50.7-0.6-0.70.8-0.7-0.80.50.7
Latency to leave start box in cocaine runway0.30.30.5-0.6-0.70.6-0.7-0.30.60.4
Latency to leave start box in cocaine runway, F0.00.00.00.10.0-0.10.00.2-0.0-0.1
Latency to leave start box in cocaine runway, M3.43.24.1-2.0-1.91.9-1.9-1.71.61.5
Std. dev. time between licks in bursts0.10.10.3-0.3-0.30.6-0.0-0.40.2-0.5
Total sessions with >9 infusions1.61.82.4-1.2-1.51.4-1.4-1.01.41.2
Short access day 1 total inactive lever presses0.80.91.3-1.0-1.11.0-1.0-0.60.90.8
Short access day 10 total inactive lever presses2.02.23.0-1.3-1.71.7-1.5-1.61.31.3
Short access day 1 total infusions0.80.91.3-0.7-1.11.0-1.0-0.71.00.9
Short access day 10 total infusions0.20.30.5-0.4-0.70.4-0.70.10.60.4
Short access total infusions0.30.30.7-0.3-0.80.6-0.7-0.20.70.5
Short access day 1 locomotion0.10.10.40.1-0.0-0.20.10.6-0.2-0.2
Short access day 10 total locomotion0.00.00.20.1-0.1-0.2-0.00.5-0.2-0.1
Short access total locomotion0.20.20.80.30.2-0.50.30.9-0.4-0.4
One hour access (0.3 mA shock)4.04.75.9-1.7-2.32.0-2.4-1.92.32.3
Compulsive drug intake1.41.52.40.91.2-0.81.50.8-1.4-1.5
One hour access (shock baseline)5.56.48.8-1.8-2.62.1-2.9-2.22.83.0
Social response proportion0.40.42.31.50.3-0.30.40.4-0.1-0.4
Social responses0.20.31.31.10.3-0.10.4-0.0-0.4-0.3
Social time0.00.00.1-0.30.00.20.2-0.2-0.2-0.1
Soleus weight2.67.78.8-2.8-3.02.8-2.9-2.82.42.6
Bone: stiffness0.60.91.41.11.0-1.10.71.2-0.7-0.6
Tibialis anterior weight10.335.237.66.16.1-6.16.06.0-5.8-5.4
Time to tail flick, vehicle, before self-admin0.40.41.00.80.6-0.70.51.0-0.5-0.4
Time to tail flick, vehicle, after self-admin0.50.60.90.50.6-0.60.70.8-1.0-0.9
Time to tail flick, test, before self-admin0.40.40.70.20.3-0.30.50.8-0.8-0.8
Time to tail flick, test, after self-admin0.10.10.2-0.4-0.30.4-0.3-0.30.30.4
Delta time to tail flick, vehicle, before/after SA0.00.00.10.00.1-0.10.2-0.0-0.4-0.4
Delta time to tail flick, test, before/after SA0.10.10.30.00.00.0-0.2-0.50.40.5
Tibia length1.23.45.32.32.0-2.31.52.1-1.1-0.9
Ambulatory time before self-admin1.81.93.01.71.5-1.61.21.4-1.0-0.9
Ambulatory time after self-admin0.10.10.20.40.4-0.40.20.4-0.1-0.1
Bone: tissue strength0.30.30.6-0.6-0.50.6-0.5-0.60.80.3
Total heroin consumption4.04.65.52.32.4-2.32.31.9-2.1-1.9
Bone: trabecular number0.60.91.61.00.9-1.00.81.3-0.8-0.9
Bone: trabecular spacing0.20.30.7-0.6-0.50.6-0.3-0.90.50.3
Bone: trabecular thickness0.30.40.6-0.6-0.60.6-0.8-0.50.70.7
Bone: trabecular tissue density4.05.76.9-2.3-2.52.3-2.4-2.62.12.4
Water consumed over 24 hours0.40.50.80.90.8-0.50.80.5-0.6-0.9
Number of responses in last shaping day0.00.00.0-0.1-0.00.10.20.0-0.1-0.1