Hub : Genes

LOC103693140

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression LOC103693140 0.05 0.03 1.7e-04 0.03 0.03 0.03 0.03 1.1e-04 1.5e-04 4.8e-04 2.4e-04
2 Eye alternative TSS XR_005488303.1 0.41 0.19 9.3e-03 0.1 0.06 0.03 0.06 1.5e-02 4.0e-02 1.3e-01 4.2e-02
3 pVTA gene expression LOC103693140 0.22 0.12 8.3e-06 0.1 0.13 0.12 0.12 3.4e-05 2.2e-06 6.7e-06 5.5e-06
4 Liver gene expression LOC103693140 0.06 0.04 3.6e-05 0.04 0.02 0.03 0.03 6.5e-05 1.3e-03 3.0e-04 1.2e-04
5 Adipose gene expression LOC103693140 0.6 0.05 0.0e+00 0.52 0.54 0.54 0.53 3.5e-68 1.3e-71 6.0e-71 4.5e-69
6 Brain gene expression LOC103693140 0.11 0.06 1.3e-09 0.1 0.11 0.1 0.1 1.3e-09 4.6e-10 2.0e-09 2.2e-09
7 PL gene expression LOC103693140 0.04 0.02 3.5e-04 0.02 0.04 0.01 0.03 3.1e-03 7.7e-05 1.6e-02 2.3e-04
8 Adipose alternative TSS XR_005488303.1 0.05 0.04 2.5e-03 0.02 0.01 0.01 0.01 3.2e-03 3.2e-02 3.1e-02 1.6e-02
9 Adipose alternative TSS XR_005488304.1 0.05 0.04 2.2e-03 0.02 0.01 0.01 0.01 2.9e-03 2.7e-02 2.5e-02 1.3e-02
10 Adipose mRNA stability LOC103693140 0.19 0.09 1.9e-15 0.1 0.12 0.12 0.12 5.3e-11 9.5e-14 2.8e-13 4.6e-13

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.20.40.90.4-0.3-1.00.1-0.4-0.9-0.8-0.50.50.6
Area under the delay curve1.11.22.6-0.1-0.2-0.81.6-1.2-1.0-1.0-1.21.21.5
BMI with tail1.23.818.6-4.31.12.6-0.21.01.82.10.7-0.71.4
BMI without tail1.83.86.5-1.52.61.8-2.02.02.02.31.8-1.8-1.4
Body weight0.62.714.8-3.80.31.8-0.30.31.11.70.3-0.32.0
Weight adjusted by age3.64.06.2-2.51.12.5-1.51.92.32.52.1-2.1-0.9
Bone surface0.10.20.6-0.7-0.20.2-0.80.40.20.30.3-0.30.1
Bone volume0.10.10.6-0.8-0.40.1-0.50.1-0.0-0.00.1-0.10.6
Breakpoint value in progressive ratio session0.10.10.60.20.8-0.20.2-0.3-0.1-0.0-0.10.10.2
Number of licking bursts0.40.52.81.70.2-0.6-0.10.1-0.3-0.50.3-0.3-1.1
Context. condit. distance diff. score0.60.81.30.2-0.6-1.00.7-0.7-1.0-1.1-1.11.10.9
Locomotion velocity, session 12.72.94.8-1.20.42.2-1.61.62.02.02.0-2.0-1.4
Locomotion distance, session 10.20.30.80.60.50.3-0.10.40.40.20.5-0.5-0.9
Locomotion velocity, session 20.30.42.30.11.50.60.3-0.50.40.60.3-0.30.1
Locomotion distance, session 20.60.95.20.12.30.7-0.10.40.70.80.8-0.8-0.7
Locomotion velocity, session 31.92.23.80.31.91.2-1.31.31.41.21.8-1.8-1.8
Locomotion distance, session 30.60.73.21.81.0-0.90.5-0.3-0.6-0.8-0.10.1-0.8
Stereotopy head waving bouts, day 30.81.01.6-1.3-1.11.1-1.01.21.00.90.8-0.8-0.6
Stereotopy head waving duration, day 31.21.42.9-1.7-1.11.4-1.21.31.21.11.0-1.0-0.4
Locomotion velocity, session 70.30.31.31.10.2-0.50.7-0.6-0.5-0.7-0.40.4-0.0
Locomotion distance, session 70.40.52.31.51.1-0.40.1-0.1-0.2-0.30.1-0.1-0.9
Stereotopy head waving bouts, day 71.61.83.1-0.90.81.3-1.71.61.41.41.3-1.3-1.3
Stereotopy head waving duration, day 71.92.34.4-1.00.81.6-2.11.71.61.61.6-1.6-1.3
Locomotion velocity, session 80.80.91.9-0.31.10.8-1.40.80.91.11.0-1.0-0.7
Locomotion distance, session 80.40.63.41.01.9-0.60.4-0.3-0.4-0.3-0.30.3-0.3
Degree of sensitization distance0.00.00.10.2-0.00.1-0.3-0.00.00.00.1-0.1-0.1
Degree of sensitization stereotypy1.11.21.9-0.81.11.2-1.41.21.21.11.1-1.1-0.9
Conditioned locomotion1.31.53.6-0.30.1-0.61.7-1.5-1.1-1.0-1.31.31.9
Cocaine response after cond. corrected2.83.18.9-3.0-1.22.4-1.51.51.91.81.3-1.3-0.1
Cocaine response after cond. not corrected1.92.16.7-2.6-1.42.0-1.11.11.51.31.0-1.00.1
Cocaine response before conditioning1.21.42.11.30.3-1.41.5-1.3-1.3-1.3-1.11.10.7
Saline control response0.81.01.5-0.2-0.80.9-1.21.21.00.71.2-1.2-1.1
Bone: connectivity density0.40.62.71.60.7-1.0-0.30.1-0.6-0.60.1-0.1-0.7
Bone: cortical apparent density0.10.10.40.6-0.4-0.20.6-0.4-0.3-0.5-0.00.0-0.0
Bone: cortical area1.01.58.5-1.8-2.90.80.6-0.40.1-0.2-0.10.11.4
Bone: cortical porosity1.31.52.70.6-0.8-1.01.4-1.7-1.3-1.2-1.21.21.5
Bone: cortical porosity2.72.94.81.1-0.7-1.81.6-2.2-1.9-1.8-1.81.81.9
Bone: cortical thickness0.91.57.3-0.2-2.7-0.31.3-1.0-0.9-1.3-0.60.61.3
Bone: cortical thickness0.60.64.00.0-2.0-0.20.8-0.7-0.5-0.7-0.20.20.7
Bone: cortical tissue density0.10.20.50.7-0.2-0.20.6-0.4-0.3-0.4-0.00.0-0.0
Condit. Reinf. active minus inactive responses2.73.04.61.41.5-1.92.1-2.1-1.7-1.4-1.81.81.5
Condit. Reinf. active-inactive response ratio3.13.44.80.7-1.3-1.72.1-2.0-1.9-1.8-2.22.22.0
Condit. Reinf. active responses1.41.79.91.43.1-1.10.9-1.1-0.8-0.3-0.60.60.3
Condit. Reinf. inactive responses3.13.618.01.04.20.5-1.41.21.11.41.8-1.8-2.0
Incentive salience index mean3.13.76.31.31.7-1.82.4-2.5-1.8-1.4-2.02.01.9
Condit. Reinf. lever presses2.12.85.11.12.0-1.42.0-2.3-1.5-1.2-1.61.61.7
Condit. Reinf. active minus inactive responses0.50.62.6-1.60.30.5-1.10.70.61.0-0.00.00.4
Condit. Reinf. active-inactive response ratio0.70.73.0-1.7-1.20.7-0.90.50.50.6-0.10.10.7
Condit. Reinf. active responses0.30.41.1-1.10.7-0.2-0.0-0.1-0.10.3-0.70.70.9
Condit. Reinf. inactive responses0.91.22.91.01.7-1.41.0-0.8-1.0-0.7-1.11.10.4
Condit. Reinf. lever presses0.70.92.10.3-1.4-0.70.9-0.8-0.9-0.9-1.11.10.9
Condit. Reinf. lever reinforcers received0.30.51.2-0.90.4-0.40.3-0.3-0.4-0.0-1.01.01.1
Conditioned reinforcement - actives0.20.20.4-0.10.50.3-0.60.60.40.30.5-0.5-0.6
Conditioned reinforcement - inactives0.40.40.9-0.7-1.00.5-0.70.90.50.30.6-0.6-0.6
Conditioned locomotion1.72.03.00.3-0.6-1.61.2-1.4-1.6-1.6-1.71.71.6
Patch foraging indifference point 0 sec0.50.71.8-0.60.21.3-0.40.51.11.01.0-1.0-0.7
Patch foraging indifference point AUC1.31.56.21.72.5-1.50.5-0.7-1.0-0.8-0.60.6-0.1
Delay disc. indifference point, 0s delay1.31.42.21.21.3-1.41.5-1.2-1.2-1.1-1.11.10.6
Delay disc. indifference point, 16s delay1.91.93.0-0.1-1.1-1.01.7-1.5-1.3-1.4-1.61.61.7
Delay disc. indifference point, 2s delay0.10.10.20.1-0.5-0.30.10.1-0.3-0.4-0.20.2-0.1
Delay disc. indifference point, 24s delay0.40.40.50.2-0.1-0.60.7-0.6-0.7-0.7-0.70.70.7
Delay disc. indifference point, 4s delay1.41.52.10.6-0.0-1.41.5-1.3-1.4-1.3-1.31.31.3
Delay disc. indifference point, 8s delay0.20.20.6-0.40.7-0.10.8-0.4-0.2-0.1-0.40.40.6
Indifference point function ln k1.42.04.4-2.0-2.11.9-1.01.21.51.30.9-0.9-0.3
Indifference point function log k1.42.04.4-2.0-2.11.9-1.01.21.51.30.9-0.9-0.3
Patch foraging total patch changes 0 sec0.61.02.4-0.90.01.5-0.50.61.21.11.2-1.2-0.7
Patch foraging total patch changes 12 sec0.20.21.00.71.0-0.6-0.0-0.2-0.4-0.4-0.10.1-0.2
Patch foraging total patch changes 18 sec0.10.10.2-0.0-0.20.30.20.00.20.20.4-0.4-0.2
Patch foraging total patch changes 24 sec0.70.81.90.41.40.4-0.60.70.70.71.1-1.1-1.3
Patch foraging total patch changes 6 sec0.50.75.50.52.30.0-0.20.10.20.40.5-0.5-0.7
Patch foraging time to switch 0 sec0.91.42.11.0-0.5-1.40.7-1.2-1.4-1.4-1.41.41.0
Patch foraging water rate 0 sec1.52.44.7-2.1-0.32.2-0.91.41.91.91.6-1.6-0.7
Patch foraging water rate 12 sec4.46.79.1-2.5-0.23.0-2.43.03.02.92.8-2.8-2.0
Patch foraging water rate 18 sec0.60.91.2-1.1-0.51.1-0.81.11.01.00.9-0.9-0.7
Patch foraging water rate 24 sec0.71.02.50.40.00.5-1.21.30.90.81.1-1.1-1.6
Patch foraging water rate 6 sec1.21.72.8-1.0-0.31.3-1.31.71.41.41.4-1.4-1.3
Seeking ratio, delayed vs. immediate footshock0.40.50.7-0.90.70.7-0.70.80.70.80.6-0.6-0.3
Distance traveled before self-admin0.00.00.2-0.2-0.40.10.0-0.3-0.00.00.0-0.00.3
Distance traveled after self-admin2.02.34.2-1.8-1.52.1-1.51.31.71.61.3-1.3-0.5
Extensor digitorum longus weight2.18.228.1-5.31.33.2-2.62.42.93.61.9-1.90.4
Bone: elastic displacement0.00.00.1-0.3-0.0-0.20.10.1-0.1-0.0-0.20.20.1
Bone: elastic work0.70.91.4-0.1-0.8-1.01.0-0.8-1.0-0.9-1.11.11.2
Bone: endosteal estimation0.92.06.1-2.50.02.0-0.91.01.61.71.1-1.10.1
Bone: endosteal perimeter0.81.69.1-3.0-0.21.5-0.40.61.11.40.2-0.21.1
Epididymis fat weight0.30.72.90.51.70.3-0.70.30.40.61.0-1.0-0.8
Delta time in closed arm before/after self-admin0.20.21.6-0.2-1.20.30.5-0.20.00.0-0.20.20.4
Delta time in open arm before/after self-admin0.50.51.60.90.1-0.4-1.10.60.0-0.10.5-0.5-1.3
Diff in mean of infusions in LGA sessions0.60.71.2-0.01.0-0.80.6-0.6-0.8-0.5-1.01.01.1
Delay discount exponential model param0.80.81.90.20.10.6-1.41.00.80.80.9-0.9-1.2
Extinction: sum of active levers before priming0.40.41.10.6-0.10.7-0.40.10.60.41.0-1.0-0.9
Active lever presses in extinction session 60.10.10.30.20.1-0.1-0.60.40.10.10.1-0.1-0.4
Bone: final force0.40.62.1-1.5-1.10.50.3-0.4-0.00.1-0.30.31.4
Bone: final moment0.50.82.5-1.4-1.60.30.5-0.6-0.2-0.2-0.50.51.5
Food consumed during 24 hour testing period2.02.44.1-1.7-1.92.0-1.01.41.71.51.4-1.4-0.9
Glucose0.91.32.3-0.80.01.1-1.41.51.21.21.2-1.2-1.1
Heart weight0.40.51.6-0.80.4-0.50.3-0.5-0.6-0.3-0.90.91.3
Delay discount hyperbolic model param0.70.71.70.10.20.6-1.30.90.80.80.9-0.9-1.1
Intermittent access intake day 1-15 change1.91.94.50.10.30.7-1.91.91.10.91.5-1.5-2.1
Intermittent access intake escalation1.61.64.20.30.30.7-1.61.61.00.81.5-1.5-2.0
Intermittent access intake escalation 20.90.91.6-0.2-0.21.0-0.90.91.00.81.3-1.3-1.1
Intermitt. access day 1 inactive lever presses0.40.54.5-0.0-2.10.10.00.1-0.0-0.4-0.00.0-0.0
Intermitt. access day 15 inactive lever presses0.50.61.0-0.0-0.4-0.80.6-0.7-0.8-0.8-0.90.91.0
Intermitt. access escalation Index0.60.51.4-1.20.40.61.2-0.80.10.3-0.10.11.1
Intermittent access day 1 total infusions0.40.54.80.1-2.20.0-0.00.0-0.1-0.40.1-0.10.0
Intermittent access day 15 total infusions0.50.61.60.4-1.30.1-0.90.80.3-0.10.7-0.7-1.1
Intermittent access terminal intake (last 3 days)0.30.32.40.4-1.6-0.4-0.1-0.0-0.4-0.6-0.10.1-0.1
Intermittent access total infusions1.11.24.0-0.0-2.00.8-1.11.10.80.41.1-1.1-1.3
Intermittent access day 1 locomotion0.40.52.00.5-1.4-0.70.0-0.3-0.7-0.9-0.50.5-0.0
Intermittent access day 15 total locomotion0.70.86.2-0.1-2.5-0.30.2-0.3-0.5-0.7-0.30.30.4
Intermittent access total locomotion0.40.51.7-0.6-1.30.6-0.70.70.50.30.6-0.6-0.6
Intermittent access standard deviation0.40.52.20.4-1.50.4-0.50.40.40.10.7-0.7-0.8
Left kidney weight0.92.48.6-2.9-0.92.0-1.21.11.61.81.0-1.00.5
Right kidney weight0.30.83.5-1.90.70.9-0.80.40.71.10.3-0.30.7
Cocaine induced anxiety0.70.81.30.81.1-0.91.1-1.0-0.9-0.8-0.80.80.5
Post-drug Anxiety1.71.95.62.12.4-1.70.8-1.0-1.3-1.2-0.90.9-0.2
Baseline Anxiety0.40.41.51.21.2-0.7-0.50.2-0.2-0.10.1-0.1-0.9
Tail length0.72.04.21.11.60.4-1.81.11.01.21.6-1.6-2.0
Length with tail0.10.30.7-0.8-0.40.4-0.7-0.10.30.80.4-0.40.5
Length without tail1.32.99.3-2.8-2.60.51.2-1.2-0.4-0.2-1.11.13.0
Times rat made contact with spout0.20.31.3-0.2-1.10.60.20.50.40.10.5-0.5-0.5
Lifetime Intake0.70.83.10.1-1.80.5-1.00.90.50.20.9-0.9-1.0
Liver weight, left2.13.44.6-1.00.61.9-2.02.12.02.02.1-2.1-1.9
Liver weight, right1.62.74.4-1.31.61.6-2.11.71.82.01.5-1.5-1.2
Locomotor activity1.72.810.5-3.2-0.82.2-1.11.21.71.81.2-1.20.4
Locomotor testing distance1.62.77.9-2.8-1.12.0-1.21.61.61.61.5-1.5-0.2
Locomotor testing rearing0.50.71.3-1.20.20.7-1.01.10.91.00.8-0.8-0.4
Locomotion in novel chamber0.60.74.70.3-2.2-0.40.6-0.4-0.5-0.8-0.60.60.3
Locomotion in novel chamber post-restriction0.50.61.30.50.4-1.00.4-0.8-0.9-0.7-1.11.10.6
Fecal boli incidents, locomotor time 11.01.12.70.40.7-0.81.6-1.4-1.0-0.9-1.01.01.1
Change in fecal boli incidents, locomotor task3.33.19.5-1.7-3.12.1-1.31.61.71.51.5-1.5-0.8
Time >=10cm from walls, locomotor time 10.20.20.6-0.80.2-0.00.5-0.3-0.2-0.2-0.40.40.8
Bouts of movement, locomotor time 10.30.31.0-0.11.00.60.9-0.30.30.40.3-0.30.2
Total resting periods, locomotor time 10.20.20.90.00.50.61.0-0.30.30.40.3-0.30.1
Rest time, locomotor task time 10.60.72.90.2-1.30.51.7-1.1-0.2-0.3-0.20.20.8
Distance moved, locomotor task time 10.50.51.80.41.4-0.4-1.20.70.10.10.3-0.3-0.9
Vertical activity count, locomotor time 10.20.20.70.20.8-0.7-0.4-0.1-0.4-0.3-0.20.20.0
Time >=10cm from walls, locomotor time 20.20.21.4-0.40.00.31.2-0.30.0-0.10.2-0.20.4
Bouts of movement, locomotor time 20.90.92.7-0.51.71.0-0.40.81.01.10.9-0.9-0.8
Total resting periods, locomotor time 21.11.22.2-0.61.51.2-0.50.91.21.31.1-1.1-1.0
Rest time, locomotor task time 20.50.53.20.4-1.80.20.9-0.7-0.1-0.3-0.30.30.4
Distance moved, locomotor task time 20.80.93.60.31.9-0.0-1.20.90.40.60.8-0.8-1.1
Vertical activity count, locomotor time 20.20.20.70.80.6-0.4-0.50.3-0.1-0.10.4-0.4-0.8
Light reinforcement 10.40.83.5-1.91.21.00.60.10.60.9-0.00.00.8
Light reinforcement 20.70.96.80.0-2.60.21.0-0.6-0.3-0.6-0.30.30.5
Bone: marrow area1.02.16.7-2.6-0.22.0-0.91.01.61.71.1-1.10.2
Bone: maximum diameter1.42.59.8-3.1-2.02.2-0.10.71.41.40.8-0.80.8
Bone: maximum force0.40.62.6-1.5-0.80.30.4-0.6-0.10.1-0.40.41.6
Bone: maximum moment0.50.93.1-1.5-1.30.20.6-0.7-0.3-0.2-0.50.51.8
Mean time between licks in bursts0.40.61.41.0-0.9-1.20.2-0.3-0.8-0.8-0.60.60.1
Mean num. licks in bursts0.70.83.3-1.8-1.31.20.20.40.80.70.3-0.30.6
Cd content in liver0.60.71.90.61.4-1.20.4-0.5-0.9-0.6-0.80.80.4
Co content in liver1.41.62.80.40.5-1.21.7-1.4-1.3-1.2-1.41.41.5
Cu content in liver0.40.51.4-0.40.7-0.60.4-0.7-0.6-0.3-0.90.91.2
Fe content in liver0.60.71.51.21.10.1-0.90.40.40.30.8-0.8-1.2
K content in liver0.30.31.1-1.10.30.5-0.70.20.40.60.1-0.10.5
Mg content in liver0.50.52.7-1.60.50.8-0.50.30.60.90.1-0.10.7
Mn content in liver0.80.93.7-1.0-1.90.10.5-0.8-0.4-0.4-0.80.81.5
Na content in liver0.80.92.0-1.00.61.4-0.50.61.21.20.9-0.9-0.3
Rb content in liver2.02.54.5-1.41.01.6-2.11.71.71.81.6-1.6-1.0
Se content in liver0.10.10.60.8-0.2-0.2-0.70.0-0.1-0.10.2-0.2-0.4
Sr content in liver0.60.60.90.90.3-0.90.9-0.9-0.8-0.6-0.90.90.4
Zn content in liver2.02.23.30.4-0.8-1.61.5-1.3-1.6-1.6-1.81.81.6
Bone: minimum diameter1.01.85.0-1.1-1.9-0.11.6-1.4-0.9-0.9-1.01.02.2
Time in familiar zone, hab. session 10.60.61.10.00.0-0.50.9-0.9-0.6-0.6-1.01.01.0
Time in novel zone, hab. session 10.30.20.5-0.0-0.50.3-0.50.70.30.20.6-0.6-0.7
Total zone transitions, hab. session 10.50.72.00.81.40.5-0.10.60.60.40.9-0.9-1.3
Total locomotion distance, hab. session 10.60.82.60.61.60.3-0.60.90.60.50.8-0.8-1.4
Locomotion velocity, hab. session 10.60.92.00.31.40.6-0.61.00.80.71.0-1.0-1.3
Time in familiar zone, hab. session 20.30.30.80.40.20.1-0.80.70.40.30.7-0.7-0.9
Time in novel zone, hab. session 20.40.41.7-0.8-1.30.20.6-0.3-0.1-0.3-0.40.40.7
Total zone transitions, hab. session 20.60.86.80.62.6-0.70.4-0.2-0.4-0.2-0.20.2-0.0
Total locomotion distance, hab. session 20.60.86.30.52.5-0.80.5-0.2-0.5-0.2-0.60.60.1
Locomotion velocity, hab. session 20.60.84.70.52.2-0.90.7-0.4-0.6-0.4-0.70.70.3
Novel to familiar place preference ratio0.30.41.1-1.00.40.10.6-0.5-0.10.1-0.60.61.0
Novelty place preference0.40.41.3-1.10.30.20.6-0.5-0.10.1-0.60.61.1
Time in novel zone, NPP test0.40.41.9-1.4-0.20.50.3-0.10.20.3-0.30.30.9
Total zone transitions, NPP test0.30.53.60.21.90.10.50.30.30.30.4-0.4-0.5
Total locomotion distance, NPP test0.70.94.50.12.10.4-0.30.80.70.80.8-0.8-1.1
Locomotion velocity, NPP test0.71.06.40.62.50.2-0.20.60.50.60.8-0.8-1.2
Intraocular pressure0.00.00.2-0.0-0.0-0.1-0.40.30.10.20.1-0.1-0.3
Delta distance traveled before/after self-admin3.03.24.6-1.9-1.52.1-2.02.12.01.81.6-1.6-1.1
Delta ambulatory time before/after self-admin2.32.55.4-1.8-2.31.8-1.71.81.61.31.2-1.2-0.7
Parametrial fat weight0.71.33.30.80.10.9-1.11.01.10.91.5-1.5-1.8
Pavlov. Cond. lever latency1.31.76.6-1.0-2.61.0-1.51.51.00.60.9-0.9-0.9
Pavlov. Cond. magazine entry latency10.613.718.52.31.5-4.14.0-4.3-4.0-3.5-4.34.33.7
Pavlov. Cond. change in total contacts3.73.95.31.21.6-2.02.2-2.3-2.0-1.7-2.32.31.9
Pavlov. Cond. index score5.67.19.72.32.4-2.93.0-3.1-2.8-2.3-2.72.72.2
Pavlov. Cond. latency score4.15.27.22.12.4-2.52.6-2.7-2.3-1.9-2.32.31.8
Pavlov. Cond. lever contacts2.22.64.11.32.0-1.52.0-2.0-1.5-1.2-1.51.51.4
Pavlov. Cond. magazine entry number9.011.314.9-2.4-1.53.7-3.63.93.63.23.8-3.8-3.1
Pavlov. Cond. intertrial magazine entries2.73.35.50.21.61.1-2.32.01.61.52.1-2.1-2.3
Pavlov. Cond. lever-magazine prob. diff.5.66.99.52.22.4-2.83.0-3.1-2.7-2.3-2.82.82.2
Pavlov. Cond. response bias7.69.212.61.91.7-3.23.4-3.5-3.2-2.8-3.53.53.0
Pavlov. Cond. lever latency1.21.62.4-0.9-0.21.4-1.51.41.41.31.4-1.4-1.1
Pavlov. Cond. magazine entry latency1.41.64.62.1-0.7-1.41.4-1.2-1.3-1.5-0.90.90.1
Pavlov. Cond. change in total contacts0.60.91.31.10.1-1.11.0-1.1-1.1-1.0-0.80.80.6
Pavlov. Cond. index score1.01.22.11.50.0-1.31.2-1.2-1.2-1.2-1.01.00.5
Pavlov. Cond. latency score0.60.81.21.1-0.4-1.01.1-0.9-0.9-1.0-0.80.80.4
Pavlov. Cond. lever contacts1.01.32.40.90.2-1.21.5-1.4-1.2-1.2-1.21.21.0
Pavlov. Cond. magazine entry number1.11.34.1-2.00.31.5-1.01.01.31.40.8-0.8-0.0
Pavlov. Cond. intertrial magazine entries0.91.11.8-1.1-0.11.1-1.41.31.11.11.1-1.1-0.8
Pavlov. Cond. lever-magazine prob. diff.1.21.52.41.6-0.1-1.51.4-1.3-1.4-1.4-1.21.20.6
Pavlov. Cond. response bias2.33.14.31.70.4-2.12.0-1.9-2.0-1.9-1.91.91.3
Time in closed arm before self-admin0.91.01.60.40.6-1.30.7-1.0-1.2-1.2-1.21.21.0
Time in closed arm after self-admin0.00.00.1-0.1-0.1-0.10.1-0.0-0.1-0.2-0.30.30.2
Time in open arm before self-admin1.21.32.8-1.5-1.21.7-0.60.81.31.41.1-1.1-0.1
Time in open arm after self-admin0.70.81.6-0.4-1.30.8-0.90.90.80.71.0-1.0-0.9
Bone: periosteal estimation0.91.97.6-2.7-1.41.9-0.30.61.31.20.9-0.90.7
Bone: periosteal perimeter0.81.36.3-2.5-0.71.6-0.30.51.11.20.5-0.50.8
Bone: post-yield work0.10.11.1-0.21.10.0-0.30.00.10.30.0-0.00.2
Progressive ratio test 1 active lever presses0.91.01.5-0.7-1.10.9-1.21.20.90.70.9-0.9-1.0
Progressive ratio test 1 breakpoint0.40.51.8-0.4-1.30.5-0.80.80.50.20.5-0.5-0.7
Progressive ratio test 1 inactive lever presses1.41.63.40.1-1.60.7-1.51.61.00.51.3-1.3-1.8
Progressive ratio test 2 active lever presses0.60.71.3-1.1-0.90.7-1.11.10.70.50.5-0.5-0.5
Progressive ratio test 2 breakpoint1.11.22.0-1.4-1.01.1-1.41.41.10.90.9-0.9-0.7
Progressive ratio test 2 inactive lever presses0.60.75.7-0.3-2.4-0.3-0.20.2-0.3-0.6-0.30.30.2
Incentive Sensitization - Responses0.50.52.6-1.6-0.90.5-0.50.60.30.3-0.10.10.5
Incentive Sensitization - Breakpoint0.30.32.0-1.4-0.70.3-0.40.50.20.2-0.20.20.5
Sum of active levers in priming session hrs 5-60.20.20.4-0.3-0.30.5-0.60.40.50.30.4-0.4-0.3
Progressive ratio3.23.75.11.20.3-2.02.2-2.3-2.0-1.9-2.22.22.0
Food seeking constrained by brief footshock1.92.33.1-0.61.11.7-1.11.51.81.71.7-1.7-1.6
Seeking ratio, punishment vs. effort6.98.410.5-2.20.73.1-3.13.23.23.23.2-3.2-2.7
Retroperitoneal fat weight0.10.51.30.11.10.6-0.30.40.60.61.0-1.0-0.6
Reaction time number correct1.01.52.6-1.61.01.0-1.61.51.21.40.9-0.9-0.7
Reaction time mean minus median0.20.20.60.80.20.40.0-0.10.20.00.7-0.7-0.5
Reaction time mean minus median AUC0.30.51.51.20.20.4-0.2-0.00.30.00.9-0.9-0.9
Reaction time num false alarms0.20.20.70.60.50.1-0.50.30.20.10.6-0.6-0.8
Reaction time num false alarms AUC0.81.11.90.10.60.8-1.21.00.90.91.4-1.4-1.3
Reaction time trials correct on left1.01.52.6-1.61.01.0-1.61.51.21.40.9-0.9-0.7
Reaction time trials on left1.11.62.7-1.51.01.0-1.71.51.21.41.0-1.0-0.8
Reaction time mean0.81.13.92.0-1.0-0.91.2-1.0-1.0-1.3-0.40.4-0.0
Reaction time mean AUC0.71.04.12.0-0.7-0.81.1-1.1-0.9-1.2-0.30.3-0.1
Median of all reaction times1.31.84.62.1-1.2-1.41.4-1.3-1.4-1.7-0.80.80.2
Reaction time omissions0.30.40.80.30.60.5-0.60.30.60.70.9-0.9-0.7
Reaction time false alarm rate0.20.21.11.1-0.10.0-0.0-0.00.1-0.10.6-0.6-0.7
Reaction time premature initiation rate0.40.61.4-0.70.80.6-1.20.80.81.00.5-0.5-0.4
Reaction time premature initiations1.01.53.2-1.51.21.0-1.81.31.21.50.8-0.8-0.6
Std. dev. reaction times0.30.42.51.6-0.0-0.30.5-0.6-0.3-0.50.2-0.2-0.5
Reaction time trials completed1.11.62.7-1.51.01.0-1.71.51.21.41.0-1.0-0.8
Reaction time trials AUC1.01.42.4-1.51.00.9-1.51.51.11.30.9-0.9-0.7
Run reversals in cocaine runway, females0.40.40.6-0.4-0.40.8-0.50.60.70.70.8-0.8-0.6
Run reversals in cocaine runway, males1.11.14.50.22.10.4-1.20.80.70.80.9-0.9-1.0
Latency to leave start box in cocaine runway0.60.71.9-1.40.61.2-0.30.40.91.10.6-0.60.1
Latency to leave start box in cocaine runway, F0.60.61.0-0.40.90.8-0.80.50.81.01.0-1.0-0.6
Latency to leave start box in cocaine runway, M0.80.73.7-1.9-0.21.10.8-0.20.50.6-0.10.10.9
Std. dev. time between licks in bursts0.40.51.4-0.10.6-1.2-0.4-0.3-0.8-0.4-1.01.00.7
Total sessions with >9 infusions1.51.74.5-0.4-1.20.8-2.11.81.10.81.2-1.2-1.6
Short access day 1 total inactive lever presses3.23.57.0-1.4-2.61.8-2.42.11.71.31.8-1.8-1.5
Short access day 10 total inactive lever presses0.50.51.30.2-1.10.5-0.50.60.50.30.9-0.9-1.0
Short access day 1 total infusions0.40.42.2-0.2-1.50.5-0.70.50.40.20.6-0.6-0.5
Short access day 10 total infusions0.40.52.90.2-1.70.4-0.40.40.3-0.00.7-0.7-0.6
Short access total infusions0.60.73.30.5-1.80.4-0.90.70.40.00.8-0.8-1.0
Short access day 1 locomotion0.20.20.6-0.4-0.50.3-0.80.50.30.20.3-0.3-0.4
Short access day 10 total locomotion0.91.12.7-0.9-1.61.3-0.60.81.00.81.1-1.1-0.6
Short access total locomotion0.30.32.4-0.0-1.60.3-0.30.20.1-0.10.4-0.4-0.5
One hour access (0.3 mA shock)0.40.54.2-0.5-2.00.50.00.00.20.00.0-0.00.4
Compulsive drug intake0.30.32.3-0.3-1.50.7-0.20.20.50.40.2-0.20.1
One hour access (shock baseline)0.10.10.30.1-0.6-0.10.4-0.3-0.3-0.40.0-0.00.2
Social response proportion0.80.92.6-0.8-0.9-0.60.3-0.9-0.8-0.6-1.21.21.6
Social responses0.00.00.2-0.30.4-0.0-0.1-0.0-0.00.1-0.20.20.2
Social time0.60.81.4-0.7-0.31.2-0.70.91.00.81.1-1.1-0.8
Soleus weight4.814.140.9-6.42.34.5-3.23.24.14.82.7-2.7-0.2
Bone: stiffness1.21.82.9-1.7-0.11.7-1.51.31.51.61.4-1.4-0.5
Tibialis anterior weight5.719.350.6-7.1-0.15.2-4.24.44.85.33.7-3.7-0.9
Time to tail flick, vehicle, before self-admin1.41.511.01.43.3-0.80.4-0.3-0.3-0.0-0.30.3-0.6
Time to tail flick, vehicle, after self-admin0.40.42.1-0.8-1.50.5-0.60.40.40.30.2-0.20.1
Time to tail flick, test, before self-admin3.23.14.51.21.3-2.11.7-1.8-2.0-1.8-2.02.01.5
Time to tail flick, test, after self-admin0.20.20.70.8-0.3-0.1-0.10.1-0.0-0.20.5-0.5-0.8
Delta time to tail flick, vehicle, before/after SA1.51.512.9-1.1-3.60.5-0.10.00.1-0.2-0.00.00.7
Delta time to tail flick, test, before/after SA2.42.13.7-0.8-1.91.7-1.11.41.41.11.7-1.7-1.3
Tibia length0.82.46.8-0.8-2.6-0.21.7-1.6-0.9-1.1-1.51.52.1
Ambulatory time before self-admin0.10.10.40.3-0.2-0.40.3-0.7-0.4-0.4-0.20.20.3
Ambulatory time after self-admin2.12.36.3-1.7-2.51.8-1.61.31.51.21.1-1.1-0.5
Bone: tissue strength0.50.50.80.9-0.7-0.70.8-0.4-0.7-0.9-0.60.60.0
Total heroin consumption1.21.52.2-0.41.41.2-1.51.11.31.51.2-1.2-0.9
Bone: trabecular number0.40.72.01.20.3-1.4-0.2-0.5-1.1-1.0-0.60.60.2
Bone: trabecular spacing0.10.10.60.20.30.40.8-0.40.10.00.2-0.2-0.1
Bone: trabecular thickness0.50.63.7-1.1-1.90.5-0.60.50.2-0.00.4-0.40.3
Bone: trabecular tissue density4.05.718.9-4.4-2.53.1-1.71.72.32.41.6-1.60.5
Water consumed over 24 hours0.20.31.70.0-1.30.10.7-0.3-0.2-0.4-0.20.20.2
Number of responses in last shaping day0.10.10.5-0.3-0.70.0-0.50.50.10.00.1-0.1-0.5