Hub : Genes

LOC103693140

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	NAcc	gene expression	LOC103693140	0.06	0.04	1.3e-09	0.06	0.06	0.06	0.06	8.1e-10	6.0e-10	2.4e-09	1.4e-09
2	RMTg	gene expression	LOC103693140	0.24	0.13	4.4e-04	0.14	0.12	0.11	0.12	1.3e-04	5.0e-04	6.4e-04	5.9e-04
3	pVTA	gene expression	LOC103693140	0.17	0.08	5.9e-11	0.09	0.14	0.13	0.14	5.6e-08	5.6e-11	1.1e-10	2.9e-11
4	Liver	gene expression	LOC103693140	0.09	0.05	9.4e-07	0.03	0.03	0.03	0.04	1.1e-04	2.2e-04	3.2e-04	2.9e-05
5	Adipose	gene expression	LOC103693140	0.54	0.04	0.0e+00	0.53	0.55	0.55	0.54	2.4e-69	5.4e-73	1.0e-72	1.3e-70
6	PL	gene expression	LOC103693140	0.03	0.02	1.0e-03	0.01	0.03	0.03	0.02	1.3e-02	9.0e-04	6.8e-04	2.9e-03
7	Brain	gene expression	LOC103693140	0.14	0.07	1.3e-13	0.14	0.15	0.15	0.15	2.2e-13	4.9e-14	4.5e-14	6.2e-14
8	Brain	alternative TSS	XR_005488304.2	0.04	0.03	6.8e-04	0.03	0.03	0.01	0.03	1.2e-03	4.0e-04	1.6e-02	1.4e-03
9	Brain	alternative TSS	XR_005488303.2	0.04	0.03	6.1e-04	0.03	0.03	0.01	0.03	1.2e-03	3.6e-04	1.5e-02	1.3e-03
10	Adipose	isoform ratio	XR_005488304.2	0.45	0.07	0.0e+00	0.34	0.4	0.42	0.39	4.8e-39	6.2e-48	6.6e-50	5.8e-46
11	Adipose	isoform ratio	XR_005488303.2	0.45	0.07	0.0e+00	0.34	0.4	0.42	0.39	1.7e-38	2.0e-47	1.3e-49	1.7e-45
12	Adipose	alternative TSS	XR_005488303.2	0.45	0.07	0.0e+00	0.3	0.37	0.38	0.37	2.9e-34	3.1e-43	4.8e-45	1.9e-42
13	Adipose	alternative TSS	XR_005488304.2	0.44	0.07	0.0e+00	0.31	0.37	0.38	0.37	1.8e-34	4.4e-43	8.0e-45	1.5e-42
14	Adipose	mRNA stability	LOC103693140	0.24	0.13	1.7e-16	0.11	0.14	0.17	0.16	6.9e-12	5.5e-15	1.8e-18	5.7e-17

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14
Bone: apparent density	0.1	0.3	0.6	-0.8	0.8	-0.6	-0.2	-0.4	0.7	0.7	0.6	-0.6	-0.1	0.1	0.1	-0.1	0.1
Area under the delay curve	0.5	0.8	1.2	-0.2	0.1	-0.6	-1.1	-1.0	0.1	1.0	1.0	-1.0	-1.0	1.0	1.0	-1.0	-1.0
BMI with tail	1.9	6.7	23.9	4.9	-4.9	3.1	1.8	1.5	-3.8	-1.4	-1.6	1.6	-1.2	1.2	1.3	-1.4	-1.7
BMI without tail	0.4	2.3	8.0	2.8	-2.6	1.8	1.2	1.0	-2.2	-1.2	-1.5	1.5	-0.2	0.2	0.3	-0.3	-0.7
Body weight	1.1	5.0	19.6	4.0	-4.4	1.9	1.3	0.3	-3.0	-0.4	-0.7	0.7	-1.8	1.8	2.0	-2.0	-2.1
Weight adjusted by age	1.4	4.0	9.3	3.0	-3.0	2.6	2.1	2.0	-2.1	-2.0	-2.1	2.1	1.1	-1.1	-1.0	1.0	0.5
Bone surface	0.1	0.1	0.6	0.3	-0.3	0.4	0.7	0.5	-0.5	-0.3	-0.3	0.3	0.3	-0.3	-0.3	0.3	0.5
Bone volume	0.0	0.0	0.3	0.2	-0.3	0.2	0.5	0.1	-0.2	0.0	0.1	-0.1	-0.0	0.0	0.1	-0.1	0.2
Breakpoint value in progressive ratio session	0.1	0.2	0.7	0.3	-0.3	-0.4	-0.1	-0.2	-0.4	0.1	-0.1	0.1	-0.4	0.4	0.5	-0.5	-0.9
Number of licking bursts	0.2	0.6	1.7	-1.3	1.3	-0.7	-0.5	-0.0	0.5	-0.1	-0.0	0.0	0.9	-0.9	-1.0	1.0	1.0
Context. condit. distance diff. score	0.6	0.7	1.4	-0.8	0.9	-0.8	-0.7	-0.8	0.8	1.0	1.2	-1.2	-0.8	0.8	0.7	-0.7	-0.1
Locomotion velocity, session 1	2.4	2.7	4.0	1.9	-1.6	1.9	1.6	1.8	-1.8	-2.0	-2.0	2.0	1.4	-1.4	-1.3	1.3	0.5
Locomotion distance, session 1	0.2	0.3	0.7	-0.2	0.2	0.2	0.1	0.5	-0.5	-0.5	-0.4	0.4	0.8	-0.8	-0.8	0.8	0.4
Locomotion velocity, session 2	0.1	0.1	0.5	0.5	-0.7	0.0	-0.0	-0.3	-0.0	-0.1	-0.6	0.6	-0.1	0.1	0.1	-0.1	-0.3
Locomotion distance, session 2	0.2	0.3	0.7	0.6	-0.6	0.3	0.3	0.3	-0.5	-0.6	-0.8	0.8	0.5	-0.4	-0.5	0.5	0.1
Locomotion velocity, session 3	1.1	1.2	2.3	0.2	0.6	0.9	0.6	1.0	-0.5	-1.1	-1.5	1.5	1.5	-1.5	-1.4	1.5	0.6
Locomotion distance, session 3	0.7	0.8	3.5	-1.5	1.9	-0.8	-1.0	-0.4	1.1	0.4	0.3	-0.3	0.7	-0.6	-0.7	0.7	0.4
Stereotopy head waving bouts, day 3	0.4	0.5	1.3	1.0	-0.6	1.2	0.8	1.0	-0.6	-0.8	-0.7	0.7	0.4	-0.4	-0.3	0.3	-0.1
Stereotopy head waving duration, day 3	0.7	0.9	2.3	1.4	-1.1	1.5	1.2	1.2	-1.0	-1.0	-0.9	0.9	0.4	-0.4	-0.3	0.3	-0.0
Locomotion velocity, session 7	0.5	0.5	1.7	-1.1	1.3	-0.8	-0.8	-0.7	1.1	0.5	0.6	-0.6	-0.1	0.1	0.1	-0.1	0.2
Locomotion distance, session 7	0.4	0.5	2.0	-1.2	1.4	-0.7	-0.6	-0.3	1.0	0.1	0.1	-0.1	0.6	-0.6	-0.6	0.7	0.7
Stereotopy head waving bouts, day 7	0.9	1.0	1.8	1.3	-0.8	1.3	1.2	1.2	-0.7	-1.1	-1.2	1.2	0.9	-0.9	-0.8	0.8	0.3
Stereotopy head waving duration, day 7	1.5	1.9	2.9	1.3	-0.9	1.6	1.7	1.6	-1.1	-1.5	-1.6	1.6	1.3	-1.3	-1.2	1.2	0.7
Locomotion velocity, session 8	0.5	0.6	1.4	0.7	-0.7	0.6	1.1	0.7	-0.7	-0.9	-1.2	1.2	0.5	-0.5	-0.5	0.6	0.5
Locomotion distance, session 8	0.1	0.2	0.6	-0.7	0.7	-0.6	-0.7	-0.5	0.5	0.3	0.2	-0.2	0.1	-0.1	-0.2	0.2	0.4
Degree of sensitization distance	0.0	0.0	0.1	-0.2	0.1	-0.2	0.0	-0.1	0.1	-0.1	-0.0	0.0	0.0	-0.0	-0.0	0.1	0.3
Degree of sensitization stereotypy	0.8	0.9	1.4	1.1	-0.7	1.2	1.2	1.1	-0.7	-1.0	-1.1	1.1	0.9	-0.9	-0.9	0.9	0.4
Conditioned locomotion	1.9	2.2	3.5	-0.2	0.0	-1.0	-1.5	-1.6	0.7	1.7	1.6	-1.6	-1.8	1.8	1.9	-1.9	-1.7
Cocaine response after cond. corrected	1.5	2.2	5.7	2.4	-1.7	2.2	2.1	1.8	-1.5	-1.7	-1.5	1.4	0.3	-0.4	-0.4	0.4	0.3
Cocaine response after cond. not corrected	1.1	1.5	3.9	2.0	-1.5	1.8	1.7	1.5	-1.4	-1.4	-1.1	1.1	0.3	-0.3	-0.3	0.3	0.2
Cocaine response before conditioning	0.7	0.9	2.4	-1.1	0.5	-1.3	-1.5	-1.2	0.6	1.1	1.1	-1.1	-0.5	0.4	0.5	-0.5	-0.5
Saline control response	0.7	1.0	1.5	0.4	-0.4	1.1	0.8	1.2	-0.9	-1.1	-1.0	1.0	1.2	-1.2	-1.2	1.2	0.7
Bone: connectivity density	0.4	0.6	2.4	-1.3	1.6	-0.6	-0.3	-0.0	0.6	0.3	0.0	-0.0	0.8	-0.8	-0.8	0.9	0.6
Bone: cortical apparent density	0.3	0.4	2.2	-0.9	1.5	-0.6	-0.8	-0.4	0.9	0.2	0.4	-0.4	0.3	-0.3	-0.2	0.2	0.1
Bone: cortical area	0.2	0.3	0.6	0.5	-0.1	0.5	0.4	-0.1	-0.0	0.2	0.5	-0.5	-0.8	0.7	0.8	-0.8	-0.4
Bone: cortical porosity	1.0	1.0	1.9	-1.1	0.2	-1.3	-1.1	-1.4	0.4	1.2	1.2	-1.2	-1.0	1.0	0.9	-0.9	-0.5
Bone: cortical porosity	2.1	2.4	4.1	-1.5	0.6	-1.9	-1.5	-2.0	1.0	1.9	1.7	-1.7	-1.5	1.6	1.5	-1.5	-0.8
Bone: cortical thickness	0.5	0.8	2.3	-0.9	1.5	-0.5	-0.5	-0.7	1.1	0.8	1.3	-1.3	-0.6	0.6	0.6	-0.6	-0.4
Bone: cortical thickness	0.3	0.3	0.5	-0.5	0.7	-0.4	-0.3	-0.5	0.6	0.4	0.6	-0.6	-0.6	0.6	0.6	-0.6	-0.4
Bone: cortical tissue density	0.3	0.4	2.2	-0.9	1.5	-0.7	-0.8	-0.4	0.9	0.2	0.4	-0.4	0.3	-0.3	-0.3	0.3	0.1
Condit. Reinf. active minus inactive responses	1.8	2.1	4.1	-1.1	0.5	-2.0	-2.0	-2.0	0.9	1.7	1.3	-1.4	-1.4	1.4	1.3	-1.3	-1.0
Condit. Reinf. active-inactive response ratio	2.2	2.3	3.6	-1.1	0.7	-1.7	-1.9	-1.8	0.9	1.8	1.8	-1.8	-1.6	1.6	1.5	-1.5	-1.0
Condit. Reinf. active responses	0.3	0.3	1.6	-0.5	0.1	-1.3	-0.8	-1.0	0.4	0.6	0.2	-0.2	-0.4	0.4	0.3	-0.3	-0.1
Condit. Reinf. inactive responses	1.3	1.6	2.9	0.4	-0.5	0.5	1.3	1.0	-0.4	-1.4	-1.7	1.7	1.6	-1.5	-1.5	1.6	1.3
Incentive salience index mean	1.9	2.5	5.0	-0.9	0.1	-2.1	-2.0	-2.2	0.9	1.9	1.5	-1.5	-1.7	1.7	1.6	-1.6	-1.0
Condit. Reinf. lever presses	1.2	1.8	4.0	-0.7	-0.2	-1.9	-1.5	-2.0	1.0	1.5	1.3	-1.3	-1.5	1.5	1.4	-1.4	-0.7
Condit. Reinf. active minus inactive responses	0.7	1.1	4.7	1.5	-2.2	0.8	1.6	0.7	-1.5	-0.8	-0.9	0.9	-0.0	0.0	-0.0	0.0	0.5
Condit. Reinf. active-inactive response ratio	0.4	0.6	2.5	1.3	-1.6	0.8	1.3	0.5	-0.8	-0.6	-0.4	0.4	-0.3	0.3	0.2	-0.2	0.2
Condit. Reinf. active responses	0.4	0.5	3.5	1.0	-1.9	0.1	0.6	-0.0	-1.1	-0.0	-0.2	0.2	-0.5	0.5	0.4	-0.4	0.1
Condit. Reinf. inactive responses	0.2	0.4	1.3	-0.7	-0.1	-1.1	-0.9	-0.8	-0.1	0.9	0.5	-0.5	-0.3	0.3	0.2	-0.2	0.1
Condit. Reinf. lever presses	0.4	0.5	0.9	-0.7	0.5	-0.9	-0.5	-0.8	0.6	0.8	1.0	-1.0	-0.7	0.7	0.7	-0.6	-0.0
Condit. Reinf. lever reinforcers received	0.3	0.4	2.6	0.7	-1.6	-0.2	0.3	-0.2	-0.9	0.2	0.1	-0.1	-0.7	0.7	0.6	-0.6	-0.0
Conditioned reinforcement - actives	0.0	0.1	0.1	0.2	0.2	0.2	0.4	0.3	-0.3	-0.3	-0.2	0.2	0.2	-0.2	-0.2	0.2	0.0
Conditioned reinforcement - inactives	0.1	0.4	0.8	0.2	0.3	0.7	0.7	0.8	-0.9	-0.6	-0.3	0.3	0.7	-0.7	-0.7	0.7	0.6
Conditioned locomotion	0.8	1.2	2.0	-0.9	0.9	-1.1	-0.9	-1.2	0.8	1.3	1.4	-1.4	-1.2	1.2	1.1	-1.1	-0.7
Patch foraging indifference point 0 sec	0.2	0.5	0.9	0.9	-0.6	0.9	0.4	0.6	-0.8	-0.8	-1.0	1.0	0.6	-0.5	-0.5	0.5	0.0
Patch foraging indifference point AUC	0.2	0.5	2.0	-1.1	0.3	-1.4	-1.1	-1.0	-0.0	1.0	0.5	-0.5	-0.3	0.3	0.3	-0.3	-0.4
Delay disc. indifference point, 0s delay	0.9	1.0	2.7	-1.2	0.8	-1.4	-1.7	-1.3	0.2	1.3	1.0	-1.0	-0.6	0.6	0.6	-0.6	-0.6
Delay disc. indifference point, 16s delay	1.4	2.0	2.9	-0.7	0.6	-1.1	-1.5	-1.6	1.1	1.6	1.7	-1.7	-1.6	1.6	1.6	-1.6	-1.1
Delay disc. indifference point, 2s delay	0.1	0.1	0.4	-0.4	0.6	0.0	-0.2	0.1	-0.0	0.0	0.3	-0.3	0.2	-0.2	-0.2	0.2	0.1
Delay disc. indifference point, 24s delay	0.3	0.4	0.6	-0.5	0.5	-0.6	-0.7	-0.7	0.5	0.8	0.8	-0.8	-0.6	0.6	0.6	-0.6	-0.4
Delay disc. indifference point, 4s delay	1.4	1.5	2.2	-1.0	0.7	-1.4	-1.4	-1.4	0.8	1.5	1.5	-1.5	-1.2	1.2	1.2	-1.2	-0.9
Delay disc. indifference point, 8s delay	0.1	0.2	0.3	0.4	-0.6	-0.0	-0.5	-0.3	-0.6	0.3	0.3	-0.3	-0.5	0.5	0.5	-0.5	-0.6
Indifference point function ln k	0.4	1.2	3.6	1.7	-1.2	1.9	1.6	1.3	-1.0	-1.2	-0.9	0.9	0.4	-0.4	-0.4	0.4	0.2
Indifference point function log k	0.4	1.2	3.6	1.7	-1.2	1.9	1.6	1.3	-1.0	-1.2	-0.9	0.9	0.4	-0.4	-0.4	0.4	0.2
Patch foraging total patch changes 0 sec	0.2	0.6	1.1	1.0	-0.7	1.1	0.6	0.7	-0.9	-0.9	-1.1	1.1	0.6	-0.6	-0.6	0.6	0.0
Patch foraging total patch changes 12 sec	0.1	0.1	0.4	-0.6	0.4	-0.5	-0.1	-0.1	-0.3	0.1	-0.0	0.0	0.2	-0.2	-0.2	0.2	0.3
Patch foraging total patch changes 18 sec	0.0	0.1	0.6	0.1	-0.1	0.1	-0.3	-0.0	-0.7	-0.0	-0.3	0.3	0.1	-0.1	-0.1	0.1	-0.4
Patch foraging total patch changes 24 sec	0.3	0.9	1.7	0.3	-0.3	0.6	0.6	0.9	-0.9	-0.9	-1.2	1.2	1.3	-1.3	-1.2	1.2	0.6
Patch foraging total patch changes 6 sec	0.1	0.2	0.5	0.0	-0.2	-0.0	-0.1	0.2	-0.5	-0.3	-0.6	0.6	0.7	-0.7	-0.7	0.7	0.3
Patch foraging time to switch 0 sec	0.4	1.6	3.9	-1.6	1.6	-1.5	-1.0	-1.3	2.0	1.3	1.4	-1.4	-0.9	0.9	0.8	-0.8	0.1
Patch foraging water rate 0 sec	0.6	2.2	5.0	2.2	-2.1	2.1	1.4	1.5	-2.0	-1.5	-1.6	1.6	0.7	-0.7	-0.6	0.6	-0.1
Patch foraging water rate 12 sec	1.7	6.9	11.1	3.0	-2.6	3.3	3.1	3.2	-2.7	-3.1	-2.8	2.8	2.0	-2.0	-1.9	1.9	1.1
Patch foraging water rate 18 sec	0.5	1.0	2.1	1.1	-0.9	1.4	1.1	1.3	-0.8	-1.0	-0.9	0.9	0.9	-0.9	-0.9	0.9	0.7
Patch foraging water rate 24 sec	1.1	1.6	2.5	0.3	-0.2	0.9	1.2	1.5	-1.0	-1.3	-1.1	1.1	1.6	-1.6	-1.6	1.5	1.4
Patch foraging water rate 6 sec	1.2	1.8	2.7	1.5	-1.4	1.6	1.4	1.6	-1.5	-1.6	-1.4	1.4	1.2	-1.2	-1.1	1.1	0.5
Seeking ratio, delayed vs. immediate footshock	0.2	0.3	1.4	0.9	-1.2	0.6	0.5	0.6	-0.3	-0.5	-0.4	0.4	-0.1	0.1	0.1	-0.1	0.0
Distance traveled before self-admin	0.0	0.0	0.2	0.2	-0.1	0.1	0.0	-0.0	0.4	-0.1	-0.2	0.2	0.1	-0.1	-0.0	0.0	-0.1
Distance traveled after self-admin	1.1	1.9	3.8	2.0	-1.5	1.8	1.8	1.4	-1.5	-1.6	-1.6	1.5	0.8	-0.8	-0.7	0.7	0.5
Extensor digitorum longus weight	2.3	9.3	32.1	5.4	-5.7	3.6	3.7	2.3	-4.0	-2.3	-2.6	2.6	-0.4	0.4	0.5	-0.5	-0.6
Bone: elastic displacement	0.1	0.1	0.3	0.1	-0.2	-0.1	-0.1	-0.1	0.0	0.3	0.2	-0.3	-0.5	0.5	0.5	-0.5	-0.5
Bone: elastic work	0.7	0.9	1.6	-0.4	0.0	-0.8	-0.6	-1.0	0.7	1.1	1.1	-1.1	-1.3	1.3	1.2	-1.2	-0.7
Bone: endosteal estimation	0.7	1.7	6.8	2.3	-2.6	1.6	1.4	0.9	-1.9	-0.9	-1.2	1.2	-0.2	0.2	0.2	-0.2	-0.1
Bone: endosteal perimeter	0.7	1.8	8.0	2.4	-2.8	1.5	1.0	0.5	-1.7	-0.4	-0.7	0.7	-1.0	1.0	1.0	-1.0	-0.6
Epididymis fat weight	0.0	0.2	0.4	-0.1	0.2	0.0	0.1	0.1	-0.6	-0.3	-0.5	0.5	0.6	-0.6	-0.6	0.6	0.6
Delta time in closed arm before/after self-admin	0.4	0.4	0.6	-0.5	0.6	-0.8	-0.7	-0.6	0.1	0.7	0.7	-0.7	-0.6	0.6	0.6	-0.6	-0.6
Delta time in open arm before/after self-admin	0.7	0.8	1.6	-0.4	0.7	0.4	0.9	1.0	0.2	-0.8	-0.7	0.7	1.2	-1.2	-1.3	1.3	1.2
Diff in mean of infusions in LGA sessions	0.6	1.1	2.3	0.1	-0.5	-1.0	-0.5	-0.9	-0.0	1.0	1.0	-1.1	-1.5	1.5	1.5	-1.5	-1.0
Delay discount exponential model param	0.4	0.5	0.8	0.1	0.0	0.5	0.9	0.8	-0.1	-0.8	-0.8	0.8	0.9	-0.8	-0.8	0.9	0.8
Extinction: sum of active levers before priming	0.3	0.5	1.3	0.7	-0.4	0.6	0.7	0.6	-0.6	-0.9	-1.1	1.1	0.7	-0.7	-0.6	0.6	-0.1
Active lever presses in extinction session 6	0.3	0.3	0.9	0.7	-0.7	0.5	0.8	0.6	-0.9	-0.7	-0.5	0.5	0.0	-0.1	0.0	-0.0	-0.3
Bone: final force	0.2	0.4	0.9	0.7	-0.8	0.2	0.3	-0.3	-0.1	0.2	0.3	-0.3	-1.0	1.0	0.9	-0.9	-0.3
Bone: final moment	0.3	0.5	1.2	0.4	-0.4	0.0	0.1	-0.5	0.2	0.5	0.6	-0.6	-1.1	1.1	1.1	-1.1	-0.4
Food consumed during 24 hour testing period	0.9	1.7	3.6	1.7	-1.5	1.9	1.3	1.5	-1.6	-1.4	-1.4	1.4	0.9	-0.9	-0.9	0.9	0.5
Glucose	1.1	1.7	2.4	1.1	-1.0	1.4	1.3	1.6	-1.4	-1.5	-1.4	1.4	1.3	-1.3	-1.3	1.2	0.6
Heart weight	0.2	0.3	1.7	0.7	-1.3	-0.1	0.1	-0.3	-0.5	0.4	-0.0	-0.0	-0.7	0.7	0.6	-0.6	-0.3
Delay discount hyperbolic model param	0.6	0.7	1.2	0.3	-0.2	0.6	1.1	1.0	-0.3	-1.0	-1.0	1.0	1.0	-1.0	-1.0	1.0	0.9
Intermittent access intake day 1-15 change	0.2	1.3	2.1	0.2	0.2	0.9	1.3	1.4	-1.0	-1.2	-0.8	0.8	1.4	-1.5	-1.4	1.4	1.4
Intermittent access intake escalation	0.2	1.0	1.9	0.3	0.1	0.9	1.4	1.2	-0.9	-1.1	-0.6	0.6	1.2	-1.2	-1.2	1.1	1.3
Intermittent access intake escalation 2	0.2	0.3	0.7	0.8	-0.5	0.7	0.9	0.7	-0.9	-0.7	-0.4	0.4	0.3	-0.3	-0.3	0.3	0.3
Intermitt. access day 1 inactive lever presses	0.0	0.4	1.8	-0.9	1.4	-0.3	-0.5	-0.2	0.1	0.5	0.9	-0.9	-0.1	0.1	0.0	-0.1	0.2
Intermitt. access day 15 inactive lever presses	0.0	0.2	0.6	0.6	-0.5	0.5	0.8	0.5	-0.8	-0.4	-0.2	0.2	0.0	-0.1	-0.0	0.0	0.1
Intermitt. access escalation Index	0.3	0.8	2.1	0.6	-1.0	-0.1	-1.0	-1.0	0.8	0.7	0.2	-0.2	-1.1	1.1	1.1	-1.1	-1.5
Intermittent access day 1 total infusions	0.1	0.4	2.7	-1.1	1.6	-0.7	-0.5	-0.2	0.8	0.2	0.5	-0.4	0.1	-0.1	-0.1	0.1	0.0
Intermittent access day 15 total infusions	0.2	0.4	2.2	-1.0	1.5	-0.4	0.1	0.1	0.6	0.0	0.4	-0.4	0.5	-0.5	-0.5	0.5	0.7
Intermittent access terminal intake (last 3 days)	0.2	0.4	2.0	-0.9	1.4	-0.6	-0.2	-0.2	0.8	0.4	0.8	-0.8	-0.2	0.2	0.2	-0.1	0.1
Intermittent access total infusions	0.2	0.3	1.5	-0.6	1.2	0.0	0.2	0.4	0.3	-0.3	-0.1	0.1	0.6	-0.6	-0.6	0.6	0.4
Intermittent access day 1 locomotion	0.5	0.9	4.2	-1.7	2.1	-0.9	-0.6	-0.4	1.5	0.5	0.8	-0.8	0.2	-0.2	-0.2	0.2	0.4
Intermittent access day 15 total locomotion	0.1	0.4	1.7	-0.9	1.3	-0.5	-0.2	-0.3	0.8	0.4	0.8	-0.8	-0.2	0.2	0.3	-0.3	-0.1
Intermittent access total locomotion	0.1	0.1	0.2	-0.0	0.4	0.4	0.5	0.4	0.1	-0.4	-0.2	0.2	0.4	-0.4	-0.3	0.3	0.3
Intermittent access standard deviation	0.0	0.3	0.5	0.3	0.5	0.5	0.7	0.7	-0.5	-0.7	-0.4	0.4	0.5	-0.5	-0.4	0.4	-0.0
Left kidney weight	0.6	4.7	11.1	3.3	-3.2	3.0	2.7	2.4	-2.8	-2.3	-2.0	2.0	0.7	-0.8	-0.7	0.7	0.4
Right kidney weight	0.8	5.9	10.9	3.3	-3.3	3.1	2.7	2.6	-3.1	-2.5	-2.6	2.5	1.4	-1.5	-1.4	1.3	0.8
Cocaine induced anxiety	0.5	1.4	2.6	-0.6	0.5	-1.0	-1.6	-1.5	0.7	1.4	1.1	-1.1	-1.2	1.2	1.2	-1.2	-1.3
Post-drug Anxiety	0.8	0.9	2.7	-1.6	1.6	-1.1	-1.4	-0.9	1.2	0.8	0.6	-0.6	0.2	-0.2	-0.2	0.2	-0.1
Baseline Anxiety	1.3	2.1	4.6	-0.6	0.8	0.5	0.8	1.3	0.3	-1.3	-1.4	1.4	2.1	-2.1	-2.1	2.1	1.6
Tail length	0.1	0.5	1.1	-0.7	0.7	-0.4	0.3	0.1	0.2	-0.3	-0.7	0.7	1.1	-1.0	-1.0	1.0	0.6
Length with tail	0.1	0.3	1.2	0.8	-1.1	0.4	0.9	0.3	-0.8	-0.4	-0.7	0.7	0.2	-0.2	-0.1	0.1	-0.0
Length without tail	0.5	2.6	11.3	2.8	-3.4	1.4	1.0	0.3	-2.1	-0.2	-0.4	0.3	-1.3	1.2	1.4	-1.4	-1.5
Times rat made contact with spout	0.1	0.1	0.3	0.1	0.2	0.5	0.0	0.5	-0.1	-0.3	-0.0	0.0	0.4	-0.4	-0.4	0.4	0.3
Lifetime Intake	0.2	0.3	1.2	-0.5	1.1	0.1	0.3	0.4	0.2	-0.3	-0.1	0.1	0.6	-0.6	-0.6	0.6	0.4
Liver weight, left	2.1	3.6	7.5	2.7	-2.6	2.5	2.0	2.0	-2.5	-2.0	-1.9	1.9	1.1	-1.1	-1.0	0.9	0.4
Liver weight, right	1.0	1.7	4.2	1.6	-1.5	1.5	1.6	1.4	-2.0	-1.4	-1.2	1.2	0.8	-0.8	-0.7	0.7	0.8
Locomotor activity	1.5	2.3	8.0	2.8	-2.8	2.2	1.8	1.1	-1.6	-1.0	-1.2	1.2	-0.4	0.4	0.5	-0.5	-0.7
Locomotor testing distance	1.0	2.5	7.0	2.7	-2.3	2.4	2.1	1.8	-1.6	-1.6	-1.4	1.4	0.4	-0.4	-0.2	0.2	-0.2
Locomotor testing rearing	0.3	1.0	2.0	1.4	-1.3	1.2	1.4	1.2	-1.2	-1.1	-1.0	1.0	0.4	-0.4	-0.4	0.4	0.2
Locomotion in novel chamber	0.2	0.2	0.6	-0.4	0.7	-0.3	-0.6	-0.2	0.0	0.4	0.7	-0.7	-0.4	0.4	0.4	-0.4	-0.6
Locomotion in novel chamber post-restriction	0.3	0.9	1.5	-1.0	0.8	-1.2	-0.8	-1.1	1.1	1.0	1.0	-1.0	-1.0	1.0	0.9	-0.9	-0.4
Fecal boli incidents, locomotor time 1	0.5	1.2	2.2	-0.8	0.5	-1.1	-1.5	-1.5	1.0	1.5	0.9	-0.9	-1.1	1.1	1.0	-1.0	-1.0
Change in fecal boli incidents, locomotor task	1.6	1.7	3.3	1.5	-1.0	1.8	1.6	1.7	-1.4	-1.6	-1.3	1.3	1.1	-1.1	-1.0	1.0	0.4
Time >=10cm from walls, locomotor time 1	0.2	0.2	0.4	0.2	-0.3	0.0	-0.2	-0.2	0.5	0.4	0.6	-0.6	-0.6	0.6	0.6	-0.6	-0.3
Bouts of movement, locomotor time 1	0.2	0.2	0.7	0.5	-0.5	0.0	-0.8	-0.4	-0.5	0.2	-0.1	0.1	-0.4	0.4	0.4	-0.3	-0.9
Total resting periods, locomotor time 1	0.1	0.1	0.5	0.5	-0.5	0.0	-0.7	-0.4	-0.4	0.1	-0.2	0.2	-0.2	0.2	0.2	-0.1	-0.7
Rest time, locomotor task time 1	1.1	1.7	4.3	0.0	0.0	-0.9	-1.8	-1.6	1.0	1.3	0.9	-0.9	-1.4	1.4	1.5	-1.5	-2.1
Distance moved, locomotor task time 1	0.1	0.4	0.8	-0.5	0.7	0.1	0.6	0.6	0.1	-0.6	-0.4	0.4	0.8	-0.8	-0.8	0.8	0.9
Vertical activity count, locomotor time 1	0.0	0.1	0.4	-0.6	0.6	-0.5	-0.1	-0.2	0.4	0.1	0.3	-0.3	0.0	-0.1	-0.0	-0.0	0.2
Time >=10cm from walls, locomotor time 2	0.1	0.3	1.4	0.3	-0.1	0.2	-1.0	-0.4	0.5	0.4	0.3	-0.3	-0.5	0.4	0.6	-0.5	-1.2
Bouts of movement, locomotor time 2	0.2	0.7	1.3	1.0	-1.1	1.0	0.3	0.7	-1.1	-0.8	-1.0	1.0	0.6	-0.6	-0.6	0.6	0.4
Total resting periods, locomotor time 2	0.2	0.9	1.7	1.2	-1.2	1.2	0.5	0.9	-1.3	-1.0	-1.2	1.2	0.7	-0.7	-0.8	0.8	0.5
Rest time, locomotor task time 2	0.2	0.4	1.0	-0.2	0.5	-0.5	-1.0	-0.7	0.5	0.7	0.4	-0.4	-0.7	0.7	0.6	-0.6	-0.8
Distance moved, locomotor task time 2	0.4	0.6	1.1	-0.1	0.2	0.4	0.7	0.8	0.2	-0.9	-0.8	0.8	1.0	-1.0	-1.0	1.0	0.7
Vertical activity count, locomotor time 2	0.2	0.4	1.0	-0.8	1.0	-0.2	-0.1	0.2	0.9	-0.3	-0.2	0.2	0.8	-0.8	-0.7	0.7	0.5
Light reinforcement 1	0.4	1.7	5.5	2.1	-2.3	0.9	0.2	-0.1	-1.5	0.0	-0.4	0.4	-1.4	1.4	1.4	-1.4	-1.6
Light reinforcement 2	0.2	0.5	1.6	-0.2	0.6	-0.3	-0.6	-0.5	0.1	0.7	0.6	-0.6	-0.8	0.8	0.9	-0.8	-1.2
Bone: marrow area	0.7	1.8	6.8	2.3	-2.6	1.6	1.4	0.9	-1.9	-0.9	-1.2	1.2	-0.2	0.2	0.2	-0.2	-0.1
Bone: maximum diameter	0.9	1.7	5.9	2.4	-2.3	1.9	1.3	0.9	-1.8	-0.8	-0.8	0.8	-0.6	0.6	0.6	-0.7	-0.6
Bone: maximum force	0.2	0.5	1.2	0.7	-0.9	0.1	0.3	-0.4	-0.1	0.3	0.3	-0.3	-1.1	1.1	1.0	-1.0	-0.3
Bone: maximum moment	0.3	0.6	1.5	0.4	-0.6	-0.0	0.1	-0.6	0.2	0.5	0.6	-0.6	-1.2	1.2	1.2	-1.2	-0.4
Mean time between licks in bursts	0.0	0.2	0.6	-0.8	0.8	-0.7	-0.5	-0.4	0.6	0.4	0.5	-0.5	-0.1	0.1	0.1	-0.1	-0.0
Mean num. licks in bursts	0.2	0.6	2.2	1.5	-1.2	1.2	0.7	0.5	-0.7	-0.3	-0.1	0.1	-0.5	0.5	0.6	-0.6	-0.7
Cd content in liver	1.1	1.2	2.7	-1.4	0.5	-1.6	-1.4	-1.4	0.8	1.3	1.2	-1.2	-0.8	0.8	0.7	-0.7	-0.5
Co content in liver	3.0	3.6	6.0	-1.3	1.3	-2.1	-2.4	-2.4	1.4	2.3	2.0	-2.1	-1.7	1.7	1.8	-1.8	-1.7
Cu content in liver	0.3	0.4	0.8	-0.2	0.2	-0.6	-0.2	-0.6	0.9	0.6	0.7	-0.7	-0.7	0.7	0.7	-0.7	-0.4
Fe content in liver	0.7	0.8	1.2	0.8	-0.5	1.1	1.0	1.0	-0.7	-1.0	-1.1	1.1	0.9	-0.9	-0.9	0.9	0.7
K content in liver	0.5	0.5	1.7	0.9	-1.3	0.5	1.3	0.6	-0.9	-0.4	-0.6	0.6	0.1	-0.1	-0.0	0.0	0.3
Mg content in liver	0.4	0.4	2.4	0.9	-1.6	0.4	0.9	0.4	-0.8	-0.3	-0.5	0.5	-0.0	-0.0	0.0	-0.1	0.1
Mn content in liver	0.5	0.5	1.3	0.4	-0.2	0.0	0.2	-0.4	0.0	0.6	0.6	-0.6	-1.1	1.1	1.1	-1.1	-0.8
Na content in liver	2.0	2.2	7.9	2.5	-2.8	1.6	1.5	1.1	-2.0	-1.1	-1.7	1.7	0.1	-0.1	-0.1	0.1	-0.2
Rb content in liver	1.0	1.2	2.2	1.1	-1.0	1.2	1.5	1.2	-1.3	-1.2	-1.2	1.2	0.8	-0.8	-0.7	0.7	0.5
Se content in liver	0.5	0.6	1.0	0.1	0.1	0.5	1.0	0.8	-0.3	-0.8	-0.8	0.8	1.0	-1.0	-1.0	1.0	0.8
Sr content in liver	0.5	0.4	1.1	-0.7	0.3	-0.9	-0.8	-1.1	0.6	1.1	0.3	-0.3	-0.5	0.5	0.4	-0.4	-0.3
Zn content in liver	0.5	0.6	1.0	-0.3	-0.6	-0.8	-0.4	-0.7	0.3	1.0	1.0	-1.0	-0.9	0.8	0.8	-0.8	-0.6
Bone: minimum diameter	1.0	1.8	3.6	-0.0	-0.2	-0.6	-1.0	-1.4	0.4	1.5	1.5	-1.5	-1.9	1.9	1.9	-1.9	-1.2
Time in familiar zone, hab. session 1	0.6	0.7	1.2	-0.1	0.1	-0.6	-0.7	-0.9	0.3	1.0	0.8	-0.8	-1.1	1.1	1.1	-1.1	-0.9
Time in novel zone, hab. session 1	0.2	0.2	0.5	-0.2	0.5	0.4	0.2	0.6	0.2	-0.5	-0.4	0.4	0.7	-0.7	-0.7	0.7	0.4
Total zone transitions, hab. session 1	0.4	0.6	1.3	-0.2	0.9	0.3	-0.1	0.6	0.2	-0.7	-0.7	0.7	1.1	-1.1	-1.1	1.1	0.3
Total locomotion distance, hab. session 1	0.5	0.7	1.6	-0.0	0.3	0.5	0.5	0.9	-0.3	-0.8	-0.8	0.8	1.3	-1.3	-1.2	1.2	0.7
Locomotion velocity, hab. session 1	0.6	0.8	1.6	0.3	-0.0	0.7	0.6	1.1	-0.5	-0.9	-0.9	0.9	1.3	-1.3	-1.2	1.2	0.7
Time in familiar zone, hab. session 2	0.3	0.3	0.7	-0.2	0.2	0.2	0.4	0.6	-0.6	-0.5	-0.4	0.4	0.8	-0.8	-0.8	0.8	0.4
Time in novel zone, hab. session 2	0.2	0.2	0.4	0.2	0.1	0.2	-0.2	-0.2	0.4	0.2	0.4	-0.4	-0.6	0.6	0.6	-0.6	-0.4
Total zone transitions, hab. session 2	0.0	0.0	0.2	-0.1	-0.1	-0.4	-0.2	-0.1	0.0	0.3	0.1	-0.1	0.1	-0.1	-0.1	0.1	-0.0
Total locomotion distance, hab. session 2	0.0	0.0	0.2	0.0	-0.5	-0.4	-0.2	-0.2	-0.2	0.4	0.2	-0.2	-0.1	0.1	0.0	-0.0	0.1
Locomotion velocity, hab. session 2	0.1	0.1	0.3	-0.1	-0.3	-0.5	-0.4	-0.3	-0.0	0.5	0.4	-0.4	-0.2	0.2	0.2	-0.2	-0.0
Novel to familiar place preference ratio	0.4	0.5	1.4	0.7	-1.0	0.0	-0.1	-0.5	-0.1	0.5	0.2	-0.2	-1.2	1.2	1.1	-1.1	-0.7
Novelty place preference	0.5	0.6	1.6	0.8	-0.9	0.1	-0.0	-0.5	-0.1	0.5	0.2	-0.2	-1.3	1.3	1.2	-1.1	-0.8
Time in novel zone, NPP test	0.4	0.5	1.2	1.0	-1.0	0.3	0.2	-0.2	-0.1	0.2	0.0	-0.0	-1.1	1.1	1.0	-1.0	-0.7
Total zone transitions, NPP test	0.1	0.2	0.6	0.4	-0.8	0.3	-0.2	0.3	-0.7	-0.4	-0.4	0.4	0.5	-0.5	-0.5	0.5	0.0
Total locomotion distance, NPP test	0.6	0.8	1.0	0.6	-0.9	0.7	0.5	0.9	-1.0	-0.9	-0.9	0.9	1.0	-1.0	-1.0	1.0	0.8
Locomotion velocity, NPP test	0.5	0.7	1.2	0.2	-0.6	0.4	0.3	0.7	-0.8	-0.8	-0.8	0.8	1.1	-1.1	-1.1	1.1	0.8
Intraocular pressure	0.0	0.0	0.1	-0.1	-0.3	-0.3	0.1	-0.2	0.2	0.0	-0.1	0.1	0.0	-0.0	-0.1	0.1	0.2
Delta distance traveled before/after self-admin	2.2	2.4	5.1	1.9	-1.5	1.9	2.2	1.9	-1.9	-1.8	-1.4	1.4	1.0	-0.9	-1.0	1.0	0.9
Delta ambulatory time before/after self-admin	0.9	1.5	4.3	1.5	-1.0	1.6	2.1	1.6	-1.4	-1.4	-1.0	1.0	0.7	-0.7	-0.7	0.7	0.8
Parametrial fat weight	0.3	0.8	2.7	-1.5	1.6	-1.1	-1.2	-0.7	1.0	0.5	0.4	-0.4	0.6	-0.6	-0.5	0.5	-0.2
Pavlov. Cond. lever latency	0.7	0.9	2.1	0.4	0.3	1.3	1.4	1.4	-0.4	-1.0	-0.6	0.6	0.9	-0.9	-0.9	0.9	0.9
Pavlov. Cond. magazine entry latency	7.9	10.1	16.8	-2.6	1.1	-4.0	-3.9	-4.1	2.1	4.0	3.4	-3.4	-3.2	3.2	3.0	-3.0	-2.0
Pavlov. Cond. change in total contacts	3.0	3.2	5.5	-1.2	0.3	-2.2	-2.2	-2.4	0.9	2.2	1.8	-1.8	-2.0	2.0	1.9	-1.9	-1.4
Pavlov. Cond. index score	4.0	5.1	9.9	-2.0	0.7	-3.1	-3.1	-3.1	1.6	2.7	2.2	-2.2	-2.0	2.0	2.0	-2.0	-1.5
Pavlov. Cond. latency score	2.9	3.7	7.7	-1.7	0.6	-2.7	-2.8	-2.7	1.3	2.3	1.8	-1.8	-1.7	1.7	1.7	-1.7	-1.4
Pavlov. Cond. lever contacts	1.8	2.1	4.4	-0.8	-0.1	-1.9	-2.1	-2.1	0.8	1.7	1.2	-1.2	-1.5	1.5	1.5	-1.5	-1.3
Pavlov. Cond. magazine entry number	6.9	8.7	14.5	2.6	-1.2	3.7	3.6	3.8	-2.2	-3.7	-3.2	3.2	2.8	-2.8	-2.7	2.7	1.7
Pavlov. Cond. intertrial magazine entries	2.3	2.8	4.3	0.6	0.2	1.2	1.9	1.9	-0.7	-1.9	-1.8	1.8	2.1	-2.0	-2.0	2.1	1.7
Pavlov. Cond. lever-magazine prob. diff.	4.0	5.0	9.6	-1.9	0.6	-3.0	-3.1	-3.1	1.5	2.7	2.2	-2.2	-2.1	2.1	2.0	-2.0	-1.5
Pavlov. Cond. response bias	6.1	7.6	13.0	-2.1	0.7	-3.4	-3.3	-3.6	1.9	3.3	2.9	-2.9	-2.8	2.8	2.7	-2.7	-1.7
Pavlov. Cond. lever latency	0.9	1.2	2.2	0.9	-0.4	1.4	1.3	1.5	-1.0	-1.4	-1.2	1.2	1.0	-1.0	-1.0	1.0	0.5
Pavlov. Cond. magazine entry latency	1.2	1.7	4.5	-2.0	2.1	-1.5	-1.7	-1.1	2.0	1.2	1.3	-1.3	-0.0	0.0	0.1	-0.1	-0.4
Pavlov. Cond. change in total contacts	0.3	0.8	1.6	-1.1	0.7	-1.3	-1.0	-1.1	1.0	1.2	0.9	-0.9	-0.5	0.5	0.5	-0.5	-0.4
Pavlov. Cond. index score	0.7	1.1	2.0	-1.3	1.0	-1.4	-1.3	-1.3	1.4	1.2	1.1	-1.1	-0.5	0.5	0.5	-0.5	-0.5
Pavlov. Cond. latency score	0.4	0.7	1.4	-1.0	0.8	-1.1	-1.1	-1.0	1.2	1.0	0.9	-0.9	-0.4	0.4	0.4	-0.4	-0.5
Pavlov. Cond. lever contacts	0.7	1.0	1.8	-0.8	0.4	-1.2	-1.2	-1.3	1.0	1.3	1.1	-1.1	-0.9	0.9	0.9	-0.9	-0.6
Pavlov. Cond. magazine entry number	1.1	1.4	3.9	1.9	-1.9	1.5	1.4	1.1	-2.0	-1.1	-1.1	1.1	-0.0	0.0	-0.0	-0.0	0.0
Pavlov. Cond. intertrial magazine entries	0.7	1.4	4.0	1.0	-1.0	1.1	1.4	1.4	-2.0	-1.3	-1.3	1.3	0.9	-0.8	-0.9	0.9	0.9
Pavlov. Cond. lever-magazine prob. diff.	0.8	1.2	2.3	-1.4	1.1	-1.5	-1.4	-1.3	1.5	1.3	1.1	-1.1	-0.5	0.5	0.5	-0.5	-0.5
Pavlov. Cond. response bias	1.9	2.6	4.5	-1.9	1.2	-2.1	-2.0	-2.0	1.8	2.0	1.8	-1.8	-1.1	1.1	1.1	-1.0	-0.6
Time in closed arm before self-admin	0.3	0.6	1.0	-0.8	0.6	-0.8	-0.8	-0.8	0.7	0.9	1.0	-1.0	-0.7	0.6	0.7	-0.7	-0.3
Time in closed arm after self-admin	0.2	0.3	0.5	-0.6	0.7	-0.6	-0.6	-0.5	0.1	0.6	0.7	-0.7	-0.3	0.3	0.3	-0.4	-0.3
Time in open arm before self-admin	0.5	0.6	2.4	1.3	-1.5	0.5	0.5	0.1	-1.0	-0.4	-0.4	0.4	-0.5	0.5	0.6	-0.6	-0.7
Time in open arm after self-admin	0.3	0.3	0.7	0.9	-0.8	0.8	0.7	0.6	-0.7	-0.7	-0.6	0.6	0.2	-0.2	-0.2	0.2	0.1
Bone: periosteal estimation	0.5	1.2	4.2	2.0	-2.1	1.5	1.1	0.7	-1.5	-0.7	-0.7	0.6	-0.4	0.4	0.5	-0.5	-0.3
Bone: periosteal perimeter	0.6	1.1	3.9	2.0	-1.9	1.5	1.1	0.6	-1.1	-0.6	-0.7	0.7	-0.6	0.6	0.6	-0.6	-0.4
Bone: post-yield work	0.0	0.0	0.1	0.2	-0.3	-0.1	0.2	-0.1	-0.1	-0.1	-0.2	0.2	-0.2	0.2	0.1	-0.1	0.4
Progressive ratio test 1 active lever presses	0.1	0.2	0.8	-0.5	0.9	0.1	0.1	0.4	0.1	-0.3	-0.2	0.2	0.7	-0.7	-0.7	0.7	0.4
Progressive ratio test 1 breakpoint	0.1	0.2	0.8	-0.6	0.9	0.0	0.0	0.3	0.1	-0.2	-0.1	0.1	0.6	-0.6	-0.6	0.6	0.3
Progressive ratio test 1 inactive lever presses	0.7	1.7	5.7	-1.5	2.4	0.3	0.3	1.1	0.3	-0.7	-0.3	0.3	1.7	-1.8	-1.7	1.7	1.6
Progressive ratio test 2 active lever presses	0.2	0.3	0.8	0.6	-0.1	0.9	0.9	0.8	-0.4	-0.7	-0.4	0.4	0.5	-0.5	-0.4	0.4	0.4
Progressive ratio test 2 breakpoint	0.3	0.3	0.8	0.6	-0.2	0.9	0.9	0.9	-0.4	-0.7	-0.4	0.4	0.5	-0.5	-0.5	0.5	0.4
Progressive ratio test 2 inactive lever presses	0.0	0.1	0.8	-0.3	0.9	0.3	0.4	0.4	0.1	-0.2	0.2	-0.2	0.2	-0.2	-0.2	0.2	0.3
Incentive Sensitization - Responses	0.1	0.2	0.8	0.9	-0.6	0.8	0.6	0.4	-0.5	-0.2	0.2	-0.2	-0.4	0.4	0.4	-0.4	0.1
Incentive Sensitization - Breakpoint	0.1	0.2	0.6	0.8	-0.6	0.7	0.5	0.4	-0.4	-0.2	0.2	-0.2	-0.4	0.4	0.3	-0.4	0.1
Sum of active levers in priming session hrs 5-6	0.2	0.2	0.5	0.5	-0.2	0.5	0.6	0.5	-0.3	-0.7	-0.7	0.7	0.4	-0.4	-0.3	0.3	0.0
Progressive ratio	1.3	3.8	5.7	-1.5	0.9	-2.3	-2.0	-2.3	1.7	2.4	2.0	-2.0	-2.1	2.1	2.0	-2.0	-1.3
Food seeking constrained by brief footshock	1.4	1.8	2.7	1.1	-0.8	1.4	1.0	1.4	-1.5	-1.5	-1.7	1.7	1.4	-1.4	-1.4	1.3	0.6
Seeking ratio, punishment vs. effort	3.7	8.3	11.9	2.9	-2.5	3.5	3.1	3.2	-3.0	-3.4	-3.2	3.2	2.6	-2.6	-2.5	2.5	1.7
Retroperitoneal fat weight	0.2	1.0	2.5	-0.3	0.6	0.4	-0.2	0.7	-0.8	-0.9	-0.9	0.9	1.6	-1.6	-1.4	1.5	0.5
Reaction time number correct	0.3	1.1	2.4	1.2	-0.9	1.4	1.6	1.3	-0.8	-1.2	-1.1	1.1	0.7	-0.7	-0.7	0.7	0.7
Reaction time mean minus median	0.0	0.2	0.7	-0.3	0.8	0.0	-0.3	0.2	-0.0	-0.4	-0.4	0.4	0.6	-0.6	-0.6	0.6	-0.1
Reaction time mean minus median AUC	0.1	0.5	1.9	-0.6	1.4	-0.0	-0.1	0.3	0.0	-0.5	-0.6	0.6	0.9	-0.9	-0.8	0.9	0.2
Reaction time num false alarms	0.3	0.5	1.5	-0.5	0.1	0.1	0.2	0.4	0.1	-0.5	-0.4	0.4	1.0	-0.9	-1.1	1.1	1.2
Reaction time num false alarms AUC	0.5	1.2	2.6	0.1	-0.4	0.7	0.8	1.0	-0.3	-1.2	-1.1	1.1	1.4	-1.4	-1.5	1.5	1.6
Reaction time trials correct on left	0.3	1.1	2.4	1.2	-0.9	1.4	1.6	1.3	-0.8	-1.2	-1.1	1.1	0.7	-0.7	-0.7	0.7	0.7
Reaction time trials on left	0.3	1.2	2.6	1.3	-0.9	1.5	1.6	1.3	-0.9	-1.2	-1.1	1.1	0.7	-0.7	-0.8	0.7	0.8
Reaction time mean	0.5	1.1	4.4	-1.8	2.1	-1.2	-1.4	-0.8	1.0	0.8	0.8	-0.8	0.2	-0.2	-0.2	0.2	-0.2
Reaction time mean AUC	0.4	0.9	3.9	-1.7	2.0	-1.2	-1.4	-0.9	0.9	0.8	0.6	-0.6	0.1	-0.1	-0.1	0.1	-0.3
Median of all reaction times	1.2	1.9	5.8	-2.3	2.4	-1.7	-1.8	-1.2	1.4	1.3	1.3	-1.3	-0.1	0.1	0.1	-0.1	-0.3
Reaction time omissions	0.3	0.5	1.0	0.3	-0.2	0.3	0.7	0.6	-0.8	-0.9	-1.0	1.0	0.7	-0.7	-0.7	0.7	0.5
Reaction time false alarm rate	0.3	0.4	0.9	-0.7	0.3	-0.2	-0.3	0.1	0.3	-0.3	-0.3	0.3	0.9	-0.8	-0.9	0.9	0.9
Reaction time premature initiation rate	0.4	0.7	2.3	0.9	-0.9	0.8	1.2	0.9	-1.5	-0.7	-1.0	1.0	0.2	-0.2	-0.3	0.3	0.3
Reaction time premature initiations	0.4	1.3	3.1	1.4	-1.2	1.3	1.8	1.3	-1.7	-1.0	-1.3	1.3	0.4	-0.3	-0.4	0.4	0.5
Std. dev. reaction times	0.1	0.5	2.7	-1.1	1.6	-0.6	-0.9	-0.3	0.6	0.1	0.0	-0.0	0.6	-0.6	-0.5	0.5	-0.1
Reaction time trials completed	0.3	1.2	2.6	1.3	-0.9	1.5	1.6	1.3	-0.9	-1.2	-1.1	1.1	0.7	-0.7	-0.8	0.7	0.8
Reaction time trials AUC	0.3	1.0	2.2	1.1	-0.8	1.3	1.5	1.2	-0.7	-1.1	-1.0	1.0	0.7	-0.7	-0.7	0.7	0.7
Run reversals in cocaine runway, females	0.4	0.5	0.8	0.5	-0.3	0.8	0.4	0.6	-0.2	-0.7	-0.8	0.8	0.9	-0.9	-0.8	0.8	0.5
Run reversals in cocaine runway, males	0.5	0.5	0.9	0.3	-0.4	0.4	0.8	0.7	-0.5	-0.7	-0.9	0.9	0.8	-0.7	-0.8	0.8	0.8
Latency to leave start box in cocaine runway	0.6	0.8	2.6	1.6	-1.6	1.3	0.8	0.6	-0.9	-0.6	-1.1	1.1	0.1	-0.1	-0.0	0.0	-0.2
Latency to leave start box in cocaine runway, F	0.9	1.1	2.1	1.1	-1.1	1.1	1.1	0.9	-0.9	-1.1	-1.5	1.5	0.9	-0.9	-0.8	0.8	0.6
Latency to leave start box in cocaine runway, M	1.1	1.1	4.5	2.1	-2.1	1.4	0.4	0.3	-0.9	-0.2	-0.5	0.5	-0.7	0.7	0.7	-0.7	-0.8
Std. dev. time between licks in bursts	0.1	0.3	0.6	-0.1	-0.7	-0.8	0.1	-0.6	-0.0	0.6	0.4	-0.4	-0.7	0.7	0.6	-0.6	0.2
Total sessions with >9 infusions	1.1	1.3	2.5	-0.6	1.2	0.6	1.1	1.3	-0.0	-1.1	-0.8	0.8	1.6	-1.6	-1.5	1.5	1.4
Short access day 1 total inactive lever presses	0.3	0.6	1.1	-0.1	0.8	0.9	1.0	1.0	0.1	-0.8	-0.3	0.3	0.8	-0.8	-0.8	0.8	1.0
Short access day 10 total inactive lever presses	0.0	0.3	0.7	-0.4	0.8	0.5	0.3	0.4	0.4	-0.2	-0.1	0.1	0.6	-0.6	-0.6	0.6	0.7
Short access day 1 total infusions	0.2	0.3	0.5	-0.0	0.4	0.5	0.7	0.6	-0.0	-0.7	-0.5	0.5	0.7	-0.7	-0.7	0.7	0.5
Short access day 10 total infusions	0.4	0.7	4.2	-1.4	2.0	-0.7	-0.5	-0.2	1.1	0.4	0.5	-0.5	0.3	-0.3	-0.3	0.3	0.3
Short access total infusions	0.4	0.6	2.7	-1.0	1.6	-0.2	0.3	0.5	0.5	-0.3	-0.1	0.2	0.9	-0.9	-0.8	0.9	0.8
Short access day 1 locomotion	0.1	0.1	0.2	-0.2	0.3	-0.2	0.1	-0.2	0.5	0.2	0.2	-0.2	-0.4	0.3	0.3	-0.4	-0.3
Short access day 10 total locomotion	0.1	0.4	0.7	-0.0	0.6	0.6	0.6	0.8	-0.1	-0.8	-0.5	0.5	0.8	-0.8	-0.8	0.8	0.4
Short access total locomotion	0.1	0.2	1.3	-0.6	1.1	0.1	0.2	0.3	0.5	-0.1	0.0	-0.0	0.4	-0.5	-0.4	0.4	0.2
One hour access (0.3 mA shock)	0.3	0.3	0.9	1.0	-0.6	0.4	0.4	0.2	-0.7	-0.2	-0.0	0.0	-0.6	0.6	0.7	-0.7	-0.8
Compulsive drug intake	0.7	1.0	2.1	1.2	-0.9	1.3	1.4	1.3	-1.4	-1.2	-0.9	0.9	0.4	-0.4	-0.4	0.4	0.3
One hour access (shock baseline)	0.2	0.4	0.7	-0.3	0.4	-0.6	-0.7	-0.7	0.6	0.7	0.6	-0.6	-0.6	0.6	0.7	-0.7	-0.8
Social response proportion	0.8	1.0	2.3	0.2	-0.6	-0.6	-0.3	-1.0	0.2	0.9	1.0	-1.0	-1.5	1.5	1.5	-1.5	-1.0
Social responses	0.0	0.1	0.2	0.1	-0.4	-0.1	-0.1	-0.1	-0.3	0.1	0.1	-0.1	-0.4	0.4	0.3	-0.4	-0.2
Social time	0.3	0.5	1.1	0.7	-0.2	0.9	0.8	0.9	-0.2	-1.0	-0.8	0.8	0.7	-0.7	-0.6	0.6	0.2
Soleus weight	5.2	15.4	50.0	6.7	-7.1	4.7	4.8	3.4	-5.2	-3.4	-3.6	3.6	0.1	-0.1	0.0	-0.0	-0.2
Bone: stiffness	1.0	1.8	2.9	1.4	-1.4	1.6	1.7	1.4	-1.2	-1.6	-1.5	1.5	0.9	-0.9	-1.0	1.0	1.0
Tibialis anterior weight	5.7	19.6	48.9	7.0	-6.9	5.8	5.8	4.6	-5.4	-4.4	-4.4	4.3	1.0	-1.0	-0.9	0.8	0.6
Time to tail flick, vehicle, before self-admin	0.4	0.5	1.8	-1.0	0.4	-1.3	-1.3	-1.0	0.3	0.8	0.4	-0.4	-0.3	0.4	0.2	-0.2	-0.2
Time to tail flick, vehicle, after self-admin	0.0	0.0	0.3	-0.1	0.1	0.0	0.1	0.1	0.5	-0.0	0.2	-0.2	-0.0	-0.0	0.1	-0.1	0.1
Time to tail flick, test, before self-admin	3.7	4.2	6.0	-1.9	1.3	-2.3	-2.4	-2.5	2.1	2.4	2.3	-2.3	-1.9	1.9	1.9	-1.9	-1.2
Time to tail flick, test, after self-admin	0.6	0.7	2.8	-1.4	1.7	-0.9	-1.1	-0.7	0.8	0.6	0.6	-0.6	0.1	-0.1	-0.0	0.0	-0.4
Delta time to tail flick, vehicle, before/after SA	0.1	0.1	0.4	0.2	0.3	0.6	0.5	0.5	0.6	-0.3	0.0	-0.0	0.3	-0.3	-0.2	0.2	0.1
Delta time to tail flick, test, before/after SA	0.7	0.9	1.8	0.8	-0.1	1.3	0.8	1.2	-0.9	-1.1	-1.0	1.0	0.9	-0.9	-0.8	0.8	0.1
Tibia length	0.7	1.9	3.8	0.0	-0.2	-0.7	-1.1	-1.5	0.3	1.5	1.4	-1.4	-1.9	1.8	1.9	-1.9	-1.5
Ambulatory time before self-admin	0.0	0.1	0.7	-0.4	0.5	-0.2	-0.4	-0.3	0.9	0.1	-0.0	0.0	0.2	-0.2	-0.1	0.2	0.1
Ambulatory time after self-admin	0.9	1.5	3.5	1.4	-0.9	1.6	1.9	1.5	-0.9	-1.6	-1.2	1.2	0.9	-0.9	-0.8	0.8	0.8
Bone: tissue strength	0.4	0.4	1.5	-1.0	1.2	-0.6	-0.8	-0.6	0.8	0.5	0.7	-0.7	-0.2	0.2	0.1	-0.1	0.0
Total heroin consumption	0.6	0.7	1.6	1.0	-1.2	0.4	1.2	0.8	-1.3	-1.0	-1.1	1.1	0.4	-0.4	-0.3	0.3	0.2
Bone: trabecular number	0.4	0.8	2.2	-1.5	1.4	-1.2	-0.7	-0.8	1.0	1.1	0.8	-0.8	-0.1	0.2	0.1	-0.1	0.2
Bone: trabecular spacing	0.0	0.1	0.2	0.3	-0.5	0.2	-0.4	-0.0	-0.3	-0.2	-0.2	0.2	0.0	-0.0	0.1	-0.1	-0.4
Bone: trabecular thickness	0.1	0.1	0.5	0.1	0.7	0.4	0.6	0.4	0.5	-0.0	0.2	-0.2	0.1	-0.1	-0.1	0.1	0.1
Bone: trabecular tissue density	2.2	3.8	11.3	3.4	-2.7	2.8	2.6	2.0	-1.9	-2.3	-1.8	1.8	0.2	-0.2	0.0	-0.0	-0.3
Water consumed over 24 hours	0.1	0.2	0.3	-0.4	0.4	-0.3	-0.5	-0.4	0.3	0.6	0.5	-0.5	-0.3	0.3	0.3	-0.3	-0.3
Number of responses in last shaping day	0.1	0.1	0.2	-0.0	0.1	0.4	0.3	0.4	-0.2	-0.1	0.0	-0.0	0.3	-0.3	-0.3	0.2	0.4