Hub : Genes

LOC103693140

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression LOC103693140 0.06 0.04 1.3e-09 0.06 0.06 0.06 0.06 8.1e-10 6.0e-10 2.4e-09 1.5e-09
2 RMTg gene expression LOC103693140 0.24 0.13 4.4e-04 0.14 0.12 0.11 0.11 1.3e-04 5.0e-04 6.4e-04 6.1e-04
3 pVTA gene expression LOC103693140 0.17 0.08 5.9e-11 0.09 0.14 0.13 0.14 5.6e-08 5.6e-11 1.2e-10 2.7e-11
4 Liver gene expression LOC103693140 0.09 0.05 9.4e-07 0.03 0.03 0.03 0.04 1.1e-04 2.2e-04 3.0e-04 2.6e-05
5 Adipose gene expression LOC103693140 0.54 0.04 0.0e+00 0.53 0.55 0.55 0.54 2.4e-69 5.4e-73 9.6e-73 1.3e-70
6 PL gene expression LOC103693140 0.03 0.02 1.0e-03 0.01 0.03 0.03 0.02 1.3e-02 9.0e-04 6.8e-04 2.8e-03
7 Brain gene expression LOC103693140 0.14 0.07 1.3e-13 0.14 0.15 0.15 0.15 2.2e-13 4.9e-14 4.5e-14 6.3e-14
8 Brain alternative TSS XR_005488304.2 0.04 0.03 6.8e-04 0.03 0.03 0.01 0.03 1.2e-03 4.0e-04 1.6e-02 1.2e-03
9 Brain alternative TSS XR_005488303.2 0.04 0.03 6.1e-04 0.03 0.03 0.01 0.03 1.2e-03 3.6e-04 1.5e-02 1.4e-03
10 Adipose isoform ratio XR_005488304.2 0.45 0.07 0.0e+00 0.34 0.4 0.42 0.39 4.8e-39 6.2e-48 6.6e-50 7.6e-46
11 Adipose isoform ratio XR_005488303.2 0.45 0.07 0.0e+00 0.34 0.4 0.42 0.39 1.7e-38 2.0e-47 1.3e-49 1.2e-45
12 Adipose alternative TSS XR_005488303.2 0.45 0.07 0.0e+00 0.3 0.37 0.38 0.37 2.9e-34 3.1e-43 4.9e-45 1.4e-42
13 Adipose alternative TSS XR_005488304.2 0.44 0.07 0.0e+00 0.31 0.37 0.38 0.37 1.8e-34 4.4e-43 8.0e-45 1.2e-42
14 Adipose mRNA stability LOC103693140 0.24 0.13 1.7e-16 0.11 0.14 0.17 0.16 6.9e-12 5.5e-15 1.8e-18 5.6e-17

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bone: apparent density0.20.30.6-0.8-0.8-0.6-0.2-0.4-0.7-0.70.6-0.60.1-0.1-0.10.1-0.1
Area under the delay curve0.70.81.2-0.2-0.1-0.6-1.1-1.0-0.1-1.01.0-1.01.0-1.0-1.01.01.0
BMI with tail1.96.723.94.94.93.11.81.53.81.4-1.61.61.2-1.2-1.31.31.7
BMI without tail0.82.38.02.82.61.81.21.02.21.2-1.51.50.2-0.2-0.30.30.7
Body weight1.15.019.64.04.41.91.30.33.00.4-0.70.71.8-1.8-2.02.02.1
Weight adjusted by age2.64.09.33.03.02.62.12.02.12.0-2.12.1-1.11.11.0-1.0-0.5
Bone surface0.10.10.60.30.30.40.70.50.50.3-0.30.3-0.30.30.3-0.3-0.5
Bone volume0.00.00.30.20.30.20.50.10.2-0.00.1-0.10.0-0.0-0.10.0-0.2
Breakpoint value in progressive ratio session0.10.20.70.30.3-0.4-0.1-0.20.4-0.1-0.10.10.4-0.4-0.50.50.9
Number of licking bursts0.40.61.7-1.3-1.3-0.7-0.5-0.0-0.50.1-0.00.0-0.90.91.0-1.0-1.0
Context. condit. distance diff. score0.60.71.4-0.8-0.9-0.8-0.7-0.8-0.8-1.01.2-1.20.8-0.8-0.70.70.1
Locomotion velocity, session 12.52.74.01.91.61.91.61.81.82.0-2.02.0-1.41.41.3-1.3-0.5
Locomotion distance, session 10.20.30.7-0.2-0.20.20.10.50.50.5-0.40.4-0.80.80.8-0.8-0.4
Locomotion velocity, session 20.10.10.50.50.70.0-0.0-0.30.00.1-0.60.60.1-0.1-0.10.10.3
Locomotion distance, session 20.20.30.70.60.60.30.30.30.50.6-0.80.8-0.50.40.5-0.5-0.1
Locomotion velocity, session 31.11.22.20.2-0.60.90.61.00.51.1-1.51.5-1.51.51.4-1.4-0.6
Locomotion distance, session 30.70.83.5-1.5-1.9-0.8-1.0-0.4-1.1-0.40.3-0.3-0.70.70.7-0.7-0.4
Stereotopy head waving bouts, day 30.40.51.31.00.61.20.81.00.60.8-0.70.7-0.40.40.3-0.30.0
Stereotopy head waving duration, day 30.70.92.31.41.11.51.21.21.01.0-0.90.9-0.40.40.3-0.30.0
Locomotion velocity, session 70.50.51.7-1.1-1.3-0.8-0.8-0.7-1.1-0.50.6-0.60.1-0.1-0.10.1-0.2
Locomotion distance, session 70.40.52.0-1.2-1.4-0.7-0.6-0.3-1.0-0.10.1-0.1-0.60.60.6-0.6-0.7
Stereotopy head waving bouts, day 70.91.01.81.30.81.31.21.20.71.1-1.21.2-0.90.90.8-0.8-0.3
Stereotopy head waving duration, day 71.51.92.91.30.91.61.71.61.11.5-1.61.6-1.31.31.2-1.2-0.7
Locomotion velocity, session 80.50.61.40.70.70.61.10.70.70.9-1.21.2-0.50.50.5-0.6-0.5
Locomotion distance, session 80.10.20.6-0.7-0.7-0.6-0.7-0.5-0.5-0.30.2-0.2-0.10.10.2-0.2-0.4
Degree of sensitization distance0.00.00.1-0.2-0.1-0.20.0-0.1-0.10.1-0.00.0-0.00.00.0-0.1-0.3
Degree of sensitization stereotypy0.90.91.41.10.71.21.21.10.71.0-1.11.1-0.90.90.9-0.9-0.4
Conditioned locomotion1.92.23.5-0.2-0.0-1.0-1.5-1.6-0.7-1.71.6-1.61.8-1.8-1.91.91.7
Cocaine response after cond. corrected1.82.25.72.41.72.22.11.81.51.7-1.51.4-0.40.30.4-0.4-0.3
Cocaine response after cond. not corrected1.31.53.92.01.51.81.71.51.41.4-1.11.1-0.30.30.3-0.3-0.2
Cocaine response before conditioning0.70.92.4-1.1-0.5-1.3-1.5-1.2-0.6-1.11.1-1.10.5-0.4-0.50.50.5
Saline control response0.81.01.50.40.41.10.81.20.91.1-1.01.0-1.21.21.2-1.2-0.7
Bone: connectivity density0.40.62.4-1.3-1.6-0.7-0.3-0.0-0.6-0.30.0-0.0-0.80.80.8-0.8-0.6
Bone: cortical apparent density0.30.42.2-0.9-1.5-0.6-0.8-0.4-0.9-0.20.4-0.4-0.30.30.2-0.2-0.1
Bone: cortical area0.20.30.60.50.10.50.4-0.10.0-0.20.5-0.50.8-0.7-0.80.80.4
Bone: cortical porosity1.01.01.9-1.1-0.2-1.3-1.1-1.4-0.4-1.21.2-1.21.0-1.0-0.90.90.5
Bone: cortical porosity2.22.44.1-1.5-0.6-1.9-1.5-2.0-1.0-1.91.7-1.71.5-1.6-1.51.50.8
Bone: cortical thickness0.50.82.3-0.9-1.5-0.5-0.5-0.7-1.1-0.81.3-1.30.6-0.6-0.60.60.4
Bone: cortical thickness0.30.30.5-0.5-0.7-0.4-0.3-0.5-0.6-0.40.6-0.60.6-0.6-0.60.60.4
Bone: cortical tissue density0.30.42.2-0.9-1.5-0.7-0.8-0.4-0.9-0.20.4-0.4-0.30.30.3-0.3-0.1
Condit. Reinf. active minus inactive responses1.92.14.1-1.1-0.5-2.0-2.0-2.0-0.9-1.71.3-1.41.4-1.4-1.31.31.0
Condit. Reinf. active-inactive response ratio2.22.33.6-1.1-0.7-1.7-1.9-1.8-0.9-1.81.8-1.81.6-1.6-1.51.51.0
Condit. Reinf. active responses0.30.31.6-0.5-0.1-1.3-0.8-1.0-0.4-0.60.2-0.20.4-0.4-0.30.30.1
Condit. Reinf. inactive responses1.31.62.90.40.50.51.31.00.41.4-1.71.7-1.61.51.5-1.6-1.3
Incentive salience index mean2.02.55.0-0.9-0.1-2.1-2.0-2.2-0.9-1.91.5-1.51.7-1.7-1.61.61.0
Condit. Reinf. lever presses1.31.84.0-0.70.2-1.9-1.5-2.0-1.0-1.51.3-1.31.5-1.5-1.41.40.7
Condit. Reinf. active minus inactive responses0.81.14.71.52.20.81.60.71.50.8-0.90.90.0-0.00.0-0.1-0.5
Condit. Reinf. active-inactive response ratio0.50.62.51.31.60.81.30.50.80.6-0.40.40.3-0.3-0.20.2-0.2
Condit. Reinf. active responses0.40.53.51.01.90.10.6-0.01.10.0-0.20.20.5-0.5-0.40.4-0.1
Condit. Reinf. inactive responses0.30.41.3-0.70.1-1.1-0.9-0.80.1-0.90.5-0.50.3-0.3-0.20.2-0.1
Condit. Reinf. lever presses0.40.50.9-0.7-0.5-0.9-0.5-0.8-0.6-0.81.0-1.00.7-0.7-0.70.60.0
Condit. Reinf. lever reinforcers received0.30.42.60.71.6-0.20.4-0.20.9-0.20.1-0.10.7-0.7-0.60.60.0
Conditioned reinforcement - actives0.00.10.10.2-0.20.20.40.30.30.3-0.20.2-0.20.20.2-0.2-0.0
Conditioned reinforcement - inactives0.30.40.80.2-0.30.70.70.80.90.6-0.30.3-0.70.80.7-0.7-0.6
Conditioned locomotion0.91.22.0-0.9-0.9-1.1-0.9-1.2-0.8-1.31.4-1.41.2-1.1-1.21.10.7
Patch foraging indifference point 0 sec0.30.50.90.90.60.90.40.60.80.8-1.01.0-0.60.50.5-0.5-0.0
Patch foraging indifference point AUC0.40.52.0-1.1-0.3-1.4-1.1-1.00.0-1.00.5-0.50.3-0.3-0.30.30.4
Delay disc. indifference point, 0s delay0.91.02.8-1.2-0.8-1.4-1.7-1.3-0.2-1.31.0-1.00.6-0.6-0.60.60.6
Delay disc. indifference point, 16s delay1.82.02.9-0.7-0.6-1.1-1.5-1.6-1.1-1.61.7-1.71.6-1.6-1.61.61.1
Delay disc. indifference point, 2s delay0.10.10.4-0.4-0.60.0-0.20.10.0-0.00.3-0.3-0.20.20.2-0.2-0.1
Delay disc. indifference point, 24s delay0.40.40.6-0.5-0.5-0.6-0.7-0.7-0.5-0.80.8-0.80.6-0.6-0.60.60.4
Delay disc. indifference point, 4s delay1.41.52.2-1.0-0.7-1.4-1.4-1.4-0.8-1.51.5-1.51.2-1.2-1.21.20.9
Delay disc. indifference point, 8s delay0.20.20.30.40.6-0.0-0.5-0.30.6-0.30.3-0.30.5-0.5-0.50.50.6
Indifference point function ln k0.71.23.61.71.21.91.61.31.01.2-0.90.9-0.40.40.4-0.4-0.2
Indifference point function log k0.71.23.61.71.21.91.61.31.01.2-0.90.9-0.40.40.4-0.4-0.2
Patch foraging total patch changes 0 sec0.30.61.11.00.71.10.60.70.90.9-1.11.1-0.60.60.6-0.6-0.0
Patch foraging total patch changes 12 sec0.10.10.4-0.6-0.4-0.5-0.1-0.10.3-0.1-0.00.0-0.20.20.2-0.2-0.3
Patch foraging total patch changes 18 sec0.00.10.60.10.10.1-0.3-0.00.70.0-0.30.3-0.10.10.1-0.10.4
Patch foraging total patch changes 24 sec0.50.91.70.30.30.60.60.90.90.9-1.21.2-1.31.31.2-1.2-0.6
Patch foraging total patch changes 6 sec0.20.20.60.00.2-0.0-0.10.20.50.3-0.60.6-0.70.70.7-0.7-0.3
Patch foraging time to switch 0 sec0.81.63.9-1.6-1.6-1.5-1.0-1.3-2.0-1.31.4-1.40.9-0.9-0.80.8-0.1
Patch foraging water rate 0 sec1.12.25.02.22.12.11.41.52.01.5-1.61.6-0.70.70.6-0.60.1
Patch foraging water rate 12 sec3.36.911.13.02.63.33.13.22.73.1-2.82.8-2.02.01.9-1.9-1.1
Patch foraging water rate 18 sec0.71.02.11.10.91.41.11.30.81.0-0.90.9-0.90.90.9-0.9-0.7
Patch foraging water rate 24 sec1.11.62.50.30.20.91.21.51.01.3-1.11.1-1.61.61.6-1.5-1.4
Patch foraging water rate 6 sec1.21.82.71.51.41.61.41.61.51.6-1.41.4-1.21.21.1-1.1-0.5
Seeking ratio, delayed vs. immediate footshock0.20.31.40.91.20.60.50.60.30.5-0.40.40.1-0.1-0.10.1-0.0
Distance traveled before self-admin0.00.00.20.20.10.10.0-0.0-0.40.1-0.20.2-0.10.10.0-0.00.1
Distance traveled after self-admin1.61.93.82.01.51.81.81.41.51.6-1.61.5-0.80.70.7-0.7-0.5
Extensor digitorum longus weight2.49.332.15.45.73.63.72.34.02.3-2.62.60.4-0.4-0.50.50.6
Bone: elastic displacement0.10.10.30.10.2-0.1-0.1-0.1-0.0-0.30.2-0.30.5-0.5-0.50.50.5
Bone: elastic work0.70.91.6-0.4-0.0-0.8-0.6-1.0-0.7-1.11.1-1.11.3-1.3-1.21.20.7
Bone: endosteal estimation0.81.86.82.32.61.61.40.91.90.9-1.21.20.2-0.2-0.20.20.1
Bone: endosteal perimeter0.81.88.02.42.81.51.00.51.70.4-0.70.71.0-1.0-1.01.00.6
Epididymis fat weight0.10.20.4-0.1-0.20.00.10.10.60.3-0.50.5-0.60.60.6-0.6-0.6
Delta time in closed arm before/after self-admin0.40.40.6-0.5-0.6-0.8-0.7-0.6-0.1-0.70.7-0.70.6-0.6-0.60.60.6
Delta time in open arm before/after self-admin0.90.81.6-0.4-0.70.40.91.0-0.20.8-0.70.7-1.21.21.3-1.3-1.2
Diff in mean of infusions in LGA sessions0.91.12.30.10.5-1.0-0.5-0.90.0-1.01.0-1.11.5-1.5-1.51.51.0
Delay discount exponential model param0.50.50.80.1-0.00.40.90.80.10.8-0.80.8-0.80.80.8-0.9-0.8
Extinction: sum of active levers before priming0.50.51.30.70.40.60.70.60.60.9-1.11.1-0.70.70.6-0.60.1
Active lever presses in extinction session 60.30.30.90.70.70.50.80.60.90.7-0.50.5-0.00.1-0.00.00.3
Bone: final force0.20.40.90.70.80.20.3-0.30.1-0.20.3-0.31.0-1.0-0.90.90.3
Bone: final moment0.30.51.20.40.40.00.1-0.5-0.2-0.50.6-0.61.1-1.1-1.11.10.4
Food consumed during 24 hour testing period1.31.73.61.71.51.91.31.51.61.4-1.41.4-0.90.90.9-0.9-0.5
Glucose1.11.72.41.11.01.41.31.61.41.5-1.41.4-1.31.31.3-1.2-0.6
Heart weight0.20.31.70.71.3-0.10.1-0.30.5-0.4-0.0-0.00.7-0.7-0.60.60.3
Delay discount hyperbolic model param0.70.71.20.30.20.61.11.00.31.0-1.01.0-1.01.01.0-1.0-0.9
Intermittent access intake day 1-15 change0.61.32.10.2-0.20.91.31.41.01.2-0.80.8-1.41.51.4-1.4-1.4
Intermittent access intake escalation0.51.01.90.3-0.10.91.41.20.91.1-0.60.6-1.21.21.2-1.1-1.3
Intermittent access intake escalation 20.30.30.70.80.50.70.90.70.90.7-0.40.4-0.30.30.3-0.3-0.3
Intermitt. access day 1 inactive lever presses0.10.41.8-0.9-1.4-0.3-0.5-0.2-0.1-0.50.9-0.90.1-0.1-0.00.1-0.2
Intermitt. access day 15 inactive lever presses0.10.20.60.60.50.50.80.50.80.4-0.20.2-0.10.10.0-0.0-0.1
Intermitt. access escalation Index0.60.82.10.61.0-0.1-1.0-1.0-0.8-0.70.2-0.21.1-1.2-1.11.11.5
Intermittent access day 1 total infusions0.30.42.7-1.1-1.6-0.7-0.5-0.2-0.8-0.20.5-0.4-0.10.10.1-0.1-0.0
Intermittent access day 15 total infusions0.30.42.2-1.0-1.5-0.40.10.1-0.6-0.00.4-0.4-0.50.50.5-0.5-0.7
Intermittent access terminal intake (last 3 days)0.30.42.0-0.9-1.4-0.6-0.2-0.2-0.8-0.40.8-0.80.2-0.2-0.20.2-0.1
Intermittent access total infusions0.20.31.5-0.6-1.20.00.20.4-0.30.3-0.10.1-0.60.60.6-0.6-0.4
Intermittent access day 1 locomotion0.70.94.2-1.7-2.1-0.9-0.6-0.4-1.5-0.50.8-0.8-0.20.20.2-0.2-0.4
Intermittent access day 15 total locomotion0.20.41.7-0.9-1.3-0.5-0.3-0.3-0.8-0.40.8-0.80.2-0.2-0.30.30.1
Intermittent access total locomotion0.10.10.2-0.0-0.40.40.50.4-0.10.4-0.20.2-0.40.40.3-0.3-0.3
Intermittent access standard deviation0.10.30.50.3-0.50.50.70.70.50.7-0.40.4-0.50.50.4-0.40.0
Left kidney weight1.04.711.13.33.23.02.72.42.82.3-2.02.0-0.70.70.7-0.7-0.4
Right kidney weight1.35.910.93.33.33.12.72.63.12.5-2.62.5-1.51.51.4-1.3-0.8
Cocaine induced anxiety1.01.42.6-0.6-0.5-1.0-1.6-1.5-0.7-1.41.1-1.11.2-1.2-1.21.21.3
Post-drug Anxiety0.80.92.7-1.6-1.6-1.1-1.4-0.9-1.2-0.80.6-0.6-0.20.20.2-0.20.1
Baseline Anxiety1.82.14.6-0.6-0.80.50.81.3-0.31.3-1.41.4-2.12.12.1-2.1-1.6
Tail length0.10.51.1-0.7-0.7-0.40.30.1-0.20.3-0.70.7-1.11.01.0-1.0-0.6
Length with tail0.10.31.20.81.10.40.90.30.80.4-0.70.7-0.20.20.1-0.10.0
Length without tail0.82.611.32.83.41.41.00.32.10.2-0.40.31.3-1.3-1.41.41.5
Times rat made contact with spout0.10.10.30.1-0.20.50.00.50.10.3-0.00.0-0.40.40.4-0.4-0.3
Lifetime Intake0.20.31.2-0.5-1.10.00.30.4-0.20.3-0.10.1-0.60.60.6-0.6-0.4
Liver weight, left2.23.67.52.72.62.52.02.02.52.0-1.91.9-1.11.11.0-0.9-0.4
Liver weight, right1.01.74.21.61.51.51.61.42.01.4-1.21.2-0.80.80.7-0.7-0.8
Locomotor activity1.52.38.02.82.82.21.81.11.61.0-1.21.20.4-0.4-0.50.50.7
Locomotor testing distance1.42.57.02.72.32.42.11.81.61.6-1.41.4-0.40.40.2-0.20.2
Locomotor testing rearing0.51.02.01.41.31.21.41.21.21.1-1.01.0-0.50.40.4-0.4-0.2
Locomotion in novel chamber0.20.20.6-0.4-0.7-0.3-0.6-0.2-0.0-0.40.7-0.70.4-0.4-0.40.40.6
Locomotion in novel chamber post-restriction0.60.91.5-1.0-0.8-1.2-0.8-1.1-1.1-1.01.0-1.01.0-1.0-0.90.90.4
Fecal boli incidents, locomotor time 10.81.22.2-0.8-0.5-1.1-1.5-1.5-1.0-1.50.9-0.91.1-1.1-1.01.01.0
Change in fecal boli incidents, locomotor task1.81.73.31.51.01.81.61.71.41.6-1.31.3-1.11.11.0-1.0-0.4
Time >=10cm from walls, locomotor time 10.20.20.40.20.30.0-0.2-0.2-0.5-0.40.6-0.60.6-0.6-0.60.60.3
Bouts of movement, locomotor time 10.20.20.70.50.50.0-0.8-0.40.5-0.2-0.10.10.4-0.4-0.40.30.9
Total resting periods, locomotor time 10.10.10.50.50.50.0-0.7-0.40.4-0.1-0.20.20.2-0.2-0.20.10.7
Rest time, locomotor task time 11.41.74.30.0-0.0-0.9-1.8-1.6-1.0-1.30.9-0.91.4-1.5-1.51.52.1
Distance moved, locomotor task time 10.30.40.8-0.5-0.70.10.60.6-0.10.6-0.40.4-0.80.80.8-0.8-0.9
Vertical activity count, locomotor time 10.00.10.4-0.6-0.6-0.5-0.1-0.2-0.4-0.10.3-0.3-0.00.10.00.0-0.2
Time >=10cm from walls, locomotor time 20.20.31.40.30.10.2-1.0-0.4-0.5-0.40.3-0.30.5-0.4-0.60.51.2
Bouts of movement, locomotor time 20.40.71.31.01.11.00.30.71.10.8-1.01.0-0.60.60.6-0.6-0.4
Total resting periods, locomotor time 20.50.91.71.21.21.20.50.91.31.0-1.21.2-0.70.70.8-0.8-0.5
Rest time, locomotor task time 20.30.41.0-0.2-0.5-0.5-1.0-0.7-0.5-0.70.4-0.40.7-0.7-0.60.60.8
Distance moved, locomotor task time 20.50.61.1-0.1-0.20.40.70.8-0.20.9-0.80.8-1.01.01.0-1.0-0.7
Vertical activity count, locomotor time 20.30.41.0-0.8-1.0-0.2-0.10.2-0.90.3-0.20.2-0.80.80.7-0.7-0.5
Light reinforcement 10.71.75.52.12.30.90.3-0.11.5-0.0-0.40.41.4-1.4-1.41.41.6
Light reinforcement 20.30.51.6-0.2-0.6-0.3-0.6-0.5-0.1-0.70.6-0.60.8-0.8-0.90.81.2
Bone: marrow area0.81.86.82.32.61.61.40.91.90.9-1.21.20.2-0.2-0.20.20.1
Bone: maximum diameter0.91.75.92.42.31.91.30.91.80.8-0.80.80.6-0.6-0.60.70.6
Bone: maximum force0.30.51.20.70.90.10.3-0.40.1-0.30.3-0.31.1-1.1-1.01.00.3
Bone: maximum moment0.30.61.50.40.6-0.00.1-0.6-0.2-0.50.6-0.61.2-1.2-1.21.20.4
Mean time between licks in bursts0.10.20.6-0.8-0.8-0.7-0.5-0.4-0.6-0.40.5-0.50.1-0.1-0.10.10.0
Mean num. licks in bursts0.40.62.21.51.21.20.70.50.70.3-0.10.10.5-0.5-0.60.60.7
Cd content in liver1.11.22.7-1.4-0.5-1.6-1.4-1.4-0.8-1.31.2-1.20.8-0.8-0.70.70.5
Co content in liver3.13.66.0-1.3-1.3-2.1-2.4-2.4-1.4-2.32.0-2.11.7-1.7-1.81.81.7
Cu content in liver0.30.40.8-0.2-0.2-0.6-0.2-0.6-0.9-0.60.7-0.70.7-0.6-0.70.70.4
Fe content in liver0.70.81.20.80.51.11.01.00.71.0-1.11.1-0.90.90.9-0.9-0.7
K content in liver0.50.51.70.91.30.51.30.60.90.4-0.60.6-0.10.10.0-0.0-0.3
Mg content in liver0.40.42.40.91.60.40.90.40.80.3-0.50.5-0.00.0-0.00.1-0.1
Mn content in liver0.50.51.30.40.20.00.2-0.4-0.0-0.60.6-0.61.1-1.1-1.11.10.8
Na content in liver2.12.27.92.52.81.61.51.12.01.1-1.71.7-0.10.10.1-0.10.2
Rb content in liver1.01.22.21.11.01.21.51.21.31.2-1.21.2-0.80.80.7-0.7-0.5
Se content in liver0.50.61.00.1-0.10.51.00.80.30.8-0.80.8-1.01.01.0-1.0-0.8
Sr content in liver0.50.41.1-0.7-0.3-0.9-0.8-1.1-0.6-1.10.3-0.30.5-0.5-0.40.40.3
Zn content in liver0.50.61.0-0.30.6-0.8-0.4-0.7-0.3-1.01.0-1.00.9-0.8-0.80.80.6
Bone: minimum diameter1.01.83.6-0.00.2-0.6-1.0-1.4-0.4-1.51.5-1.51.9-1.9-1.91.91.2
Time in familiar zone, hab. session 10.70.71.2-0.1-0.1-0.6-0.7-0.9-0.3-1.00.8-0.81.1-1.1-1.11.10.9
Time in novel zone, hab. session 10.20.20.5-0.2-0.50.40.20.6-0.20.5-0.40.4-0.70.70.7-0.7-0.4
Total zone transitions, hab. session 10.40.61.3-0.2-0.90.3-0.10.6-0.20.7-0.70.7-1.11.11.1-1.1-0.3
Total locomotion distance, hab. session 10.50.71.6-0.0-0.30.50.50.90.30.8-0.80.8-1.31.31.2-1.2-0.7
Locomotion velocity, hab. session 10.60.81.60.30.00.70.61.10.50.9-0.90.9-1.31.31.2-1.2-0.7
Time in familiar zone, hab. session 20.30.30.7-0.2-0.20.20.40.60.60.5-0.40.4-0.80.80.8-0.8-0.4
Time in novel zone, hab. session 20.20.20.40.2-0.10.2-0.2-0.2-0.4-0.20.4-0.40.6-0.6-0.60.60.4
Total zone transitions, hab. session 20.00.00.2-0.10.1-0.4-0.2-0.1-0.0-0.30.1-0.1-0.10.10.1-0.10.0
Total locomotion distance, hab. session 20.00.00.20.00.5-0.4-0.2-0.20.2-0.40.2-0.20.1-0.1-0.00.0-0.1
Locomotion velocity, hab. session 20.10.10.3-0.10.3-0.5-0.4-0.30.0-0.50.4-0.40.2-0.2-0.20.20.0
Novel to familiar place preference ratio0.50.51.40.71.00.0-0.1-0.50.1-0.50.2-0.21.2-1.2-1.11.10.7
Novelty place preference0.60.61.60.80.90.1-0.0-0.50.1-0.50.2-0.21.3-1.3-1.21.10.8
Time in novel zone, NPP test0.50.51.21.01.00.30.2-0.20.1-0.20.0-0.01.1-1.1-1.01.00.7
Total zone transitions, NPP test0.10.20.60.40.80.3-0.20.30.70.4-0.40.4-0.50.50.5-0.5-0.0
Total locomotion distance, NPP test0.60.81.00.60.90.70.50.91.00.9-0.90.9-1.01.01.0-1.0-0.8
Locomotion velocity, NPP test0.50.71.20.20.60.40.30.70.80.8-0.80.8-1.11.11.1-1.1-0.8
Intraocular pressure0.00.00.1-0.10.3-0.30.1-0.2-0.2-0.0-0.10.1-0.00.00.1-0.1-0.2
Delta distance traveled before/after self-admin2.22.45.11.91.51.92.21.91.91.8-1.41.4-1.00.91.0-1.0-0.9
Delta ambulatory time before/after self-admin1.21.54.31.51.01.62.11.61.41.4-1.01.0-0.70.70.7-0.7-0.8
Parametrial fat weight0.30.82.7-1.5-1.6-1.1-1.2-0.7-1.0-0.50.4-0.4-0.60.60.5-0.50.2
Pavlov. Cond. lever latency0.70.92.10.4-0.31.31.41.40.41.0-0.60.6-0.90.90.9-0.9-0.9
Pavlov. Cond. magazine entry latency7.910.116.8-2.6-1.1-4.0-3.9-4.1-2.1-4.03.4-3.43.2-3.2-3.03.02.0
Pavlov. Cond. change in total contacts3.03.25.5-1.2-0.3-2.2-2.2-2.4-0.9-2.21.8-1.82.0-2.0-1.91.91.4
Pavlov. Cond. index score4.15.19.9-2.0-0.7-3.1-3.1-3.1-1.6-2.72.2-2.22.0-2.0-2.02.01.5
Pavlov. Cond. latency score2.93.77.7-1.7-0.6-2.7-2.8-2.7-1.3-2.31.8-1.81.7-1.7-1.71.71.4
Pavlov. Cond. lever contacts1.82.14.4-0.80.1-1.9-2.1-2.1-0.8-1.71.2-1.21.5-1.5-1.51.51.3
Pavlov. Cond. magazine entry number6.98.714.52.61.23.73.63.82.23.7-3.23.2-2.82.82.7-2.7-1.7
Pavlov. Cond. intertrial magazine entries2.32.84.30.6-0.21.21.91.90.71.9-1.81.8-2.12.02.0-2.1-1.7
Pavlov. Cond. lever-magazine prob. diff.4.15.09.6-1.9-0.6-3.0-3.1-3.1-1.5-2.72.2-2.22.1-2.1-2.02.01.5
Pavlov. Cond. response bias6.27.613.0-2.1-0.7-3.4-3.3-3.6-1.9-3.32.9-2.92.8-2.8-2.72.71.7
Pavlov. Cond. lever latency0.91.22.20.90.41.41.31.51.01.4-1.21.2-1.01.01.0-1.0-0.5
Pavlov. Cond. magazine entry latency1.41.74.5-2.0-2.1-1.5-1.7-1.1-2.0-1.21.3-1.30.0-0.0-0.10.10.4
Pavlov. Cond. change in total contacts0.50.81.6-1.1-0.7-1.3-1.0-1.1-1.0-1.20.9-0.90.5-0.5-0.50.50.4
Pavlov. Cond. index score0.81.12.0-1.3-1.0-1.4-1.3-1.3-1.4-1.21.1-1.10.5-0.5-0.50.50.5
Pavlov. Cond. latency score0.50.71.4-1.0-0.8-1.1-1.1-1.0-1.2-1.00.9-0.90.4-0.4-0.40.40.5
Pavlov. Cond. lever contacts0.71.01.8-0.8-0.4-1.2-1.2-1.3-1.0-1.31.1-1.10.9-0.9-0.90.90.6
Pavlov. Cond. magazine entry number1.21.43.91.91.91.51.41.12.01.1-1.11.10.0-0.00.00.0-0.0
Pavlov. Cond. intertrial magazine entries0.91.44.01.01.01.11.41.42.01.3-1.31.3-0.90.80.9-0.9-0.9
Pavlov. Cond. lever-magazine prob. diff.0.91.22.3-1.4-1.1-1.5-1.4-1.3-1.5-1.31.1-1.10.5-0.5-0.50.50.5
Pavlov. Cond. response bias1.92.64.5-1.9-1.2-2.1-2.0-2.0-1.8-2.01.8-1.81.1-1.1-1.11.00.6
Time in closed arm before self-admin0.50.61.0-0.8-0.6-0.8-0.8-0.8-0.7-0.91.0-1.00.7-0.6-0.70.70.3
Time in closed arm after self-admin0.20.30.5-0.6-0.7-0.6-0.6-0.5-0.1-0.60.7-0.70.3-0.3-0.30.40.3
Time in open arm before self-admin0.50.62.41.31.50.50.50.11.00.4-0.40.40.6-0.5-0.60.60.7
Time in open arm after self-admin0.30.30.70.90.80.80.70.60.70.7-0.60.6-0.20.20.2-0.2-0.1
Bone: periosteal estimation0.61.24.22.02.11.51.20.71.50.7-0.70.60.4-0.4-0.50.50.3
Bone: periosteal perimeter0.61.13.92.01.91.51.10.61.10.6-0.70.70.6-0.6-0.60.60.4
Bone: post-yield work0.00.00.10.20.3-0.10.2-0.10.10.1-0.20.20.2-0.2-0.10.1-0.4
Progressive ratio test 1 active lever presses0.20.20.8-0.5-0.90.10.10.4-0.10.3-0.20.2-0.70.70.7-0.7-0.4
Progressive ratio test 1 breakpoint0.20.20.8-0.6-0.90.00.00.3-0.10.2-0.10.1-0.60.60.6-0.6-0.3
Progressive ratio test 1 inactive lever presses1.21.75.7-1.5-2.40.30.31.1-0.30.7-0.30.3-1.71.81.7-1.7-1.6
Progressive ratio test 2 active lever presses0.30.30.80.60.10.90.90.80.40.7-0.40.4-0.50.50.4-0.4-0.4
Progressive ratio test 2 breakpoint0.30.30.80.60.20.90.90.90.40.7-0.40.4-0.50.50.5-0.5-0.4
Progressive ratio test 2 inactive lever presses0.10.10.8-0.3-0.90.30.40.4-0.10.20.2-0.2-0.20.20.2-0.2-0.3
Incentive Sensitization - Responses0.20.20.80.90.60.80.60.40.50.20.2-0.20.4-0.4-0.40.4-0.1
Incentive Sensitization - Breakpoint0.20.20.60.80.60.70.60.40.40.20.2-0.20.4-0.3-0.30.4-0.1
Sum of active levers in priming session hrs 5-60.20.20.50.50.20.50.60.50.30.7-0.70.7-0.40.40.3-0.3-0.0
Progressive ratio2.43.85.7-1.5-0.9-2.3-2.0-2.3-1.7-2.42.0-2.02.1-2.1-2.02.01.3
Food seeking constrained by brief footshock1.41.72.71.10.81.41.01.41.51.5-1.71.7-1.41.41.4-1.3-0.6
Seeking ratio, punishment vs. effort5.88.311.92.92.53.53.13.23.03.4-3.23.2-2.62.62.5-2.5-1.7
Retroperitoneal fat weight0.21.02.5-0.3-0.60.4-0.20.70.80.9-0.90.9-1.61.61.4-1.5-0.5
Reaction time number correct0.61.12.41.20.91.41.61.30.81.2-1.11.1-0.70.70.7-0.7-0.7
Reaction time mean minus median0.10.20.7-0.3-0.80.0-0.30.20.00.4-0.40.4-0.60.60.6-0.60.1
Reaction time mean minus median AUC0.20.51.9-0.6-1.4-0.0-0.10.3-0.00.5-0.60.6-0.90.90.8-0.9-0.2
Reaction time num false alarms0.30.51.5-0.5-0.10.10.20.4-0.10.5-0.40.4-1.00.91.1-1.1-1.2
Reaction time num false alarms AUC0.81.22.60.10.40.70.81.00.31.2-1.11.1-1.41.41.5-1.5-1.6
Reaction time trials correct on left0.61.12.41.20.91.41.61.30.81.2-1.11.1-0.70.70.7-0.7-0.7
Reaction time trials on left0.61.22.61.30.91.51.61.30.91.2-1.11.1-0.70.70.8-0.7-0.8
Reaction time mean0.71.14.4-1.8-2.1-1.2-1.4-0.8-1.0-0.80.8-0.8-0.20.20.2-0.20.2
Reaction time mean AUC0.60.93.9-1.7-2.0-1.2-1.4-0.9-0.9-0.80.6-0.6-0.10.10.1-0.10.3
Median of all reaction times1.31.95.8-2.3-2.4-1.7-1.8-1.2-1.4-1.31.3-1.30.1-0.1-0.10.10.3
Reaction time omissions0.30.51.00.30.20.30.70.60.80.9-1.01.0-0.70.70.7-0.7-0.5
Reaction time false alarm rate0.30.40.9-0.7-0.3-0.2-0.30.1-0.30.3-0.30.3-0.90.90.9-0.9-0.9
Reaction time premature initiation rate0.50.72.30.90.90.81.20.91.50.7-1.01.0-0.20.20.3-0.3-0.3
Reaction time premature initiations0.71.33.11.41.21.31.81.31.71.0-1.31.3-0.40.30.4-0.4-0.5
Std. dev. reaction times0.30.52.7-1.1-1.6-0.6-0.9-0.3-0.6-0.10.0-0.0-0.50.50.5-0.50.1
Reaction time trials completed0.61.22.61.30.91.51.61.30.91.2-1.11.1-0.70.70.8-0.7-0.8
Reaction time trials AUC0.51.02.21.10.81.31.51.20.71.1-1.01.0-0.70.70.7-0.7-0.7
Run reversals in cocaine runway, females0.50.50.80.50.30.80.40.60.20.7-0.80.8-0.90.90.8-0.8-0.5
Run reversals in cocaine runway, males0.50.50.90.30.40.40.80.70.50.7-0.90.9-0.80.70.8-0.8-0.8
Latency to leave start box in cocaine runway0.70.82.61.61.61.30.80.60.90.6-1.11.1-0.10.10.0-0.00.2
Latency to leave start box in cocaine runway, F1.01.12.11.11.11.11.10.90.91.1-1.51.5-0.90.90.8-0.8-0.6
Latency to leave start box in cocaine runway, M1.11.14.52.12.11.40.40.30.90.2-0.50.50.7-0.7-0.70.70.8
Std. dev. time between licks in bursts0.20.30.6-0.10.7-0.80.1-0.60.0-0.60.4-0.40.7-0.7-0.60.6-0.2
Total sessions with >9 infusions1.11.32.5-0.6-1.20.61.11.30.01.1-0.80.8-1.61.61.5-1.5-1.4
Short access day 1 total inactive lever presses0.40.61.1-0.1-0.80.91.01.0-0.10.8-0.30.3-0.80.80.8-0.8-1.0
Short access day 10 total inactive lever presses0.10.30.7-0.4-0.80.50.30.4-0.40.2-0.10.1-0.60.70.6-0.6-0.7
Short access day 1 total infusions0.20.30.5-0.0-0.40.50.70.60.00.7-0.50.5-0.70.70.7-0.7-0.5
Short access day 10 total infusions0.50.74.2-1.4-2.0-0.7-0.5-0.2-1.1-0.40.5-0.5-0.30.30.3-0.3-0.3
Short access total infusions0.40.62.7-1.0-1.6-0.20.30.5-0.50.3-0.10.2-0.90.90.8-0.9-0.8
Short access day 1 locomotion0.10.10.2-0.2-0.3-0.20.1-0.2-0.5-0.20.2-0.20.3-0.3-0.30.40.3
Short access day 10 total locomotion0.20.40.7-0.0-0.60.60.60.80.10.8-0.50.5-0.80.80.8-0.8-0.4
Short access total locomotion0.20.21.3-0.6-1.10.10.20.3-0.50.10.0-0.0-0.40.50.4-0.4-0.2
One hour access (0.3 mA shock)0.30.30.91.00.60.40.40.20.70.2-0.00.00.6-0.6-0.70.70.8
Compulsive drug intake0.81.02.11.20.91.31.41.31.41.2-0.90.9-0.40.40.4-0.4-0.3
One hour access (shock baseline)0.30.40.7-0.3-0.4-0.6-0.7-0.7-0.6-0.70.6-0.60.6-0.6-0.70.70.8
Social response proportion0.91.02.30.20.6-0.6-0.3-1.0-0.2-0.91.0-1.01.5-1.5-1.51.51.0
Social responses0.10.10.20.10.4-0.1-0.1-0.10.3-0.10.1-0.10.4-0.4-0.30.40.2
Social time0.40.51.10.70.20.90.80.90.21.0-0.80.8-0.70.70.6-0.6-0.2
Soleus weight5.215.450.06.77.14.74.83.45.23.4-3.63.6-0.10.10.00.00.2
Bone: stiffness1.11.82.91.41.41.61.71.41.21.6-1.51.5-0.90.91.0-1.0-1.0
Tibialis anterior weight5.819.748.97.06.95.85.84.65.44.4-4.44.3-1.01.00.9-0.9-0.6
Time to tail flick, vehicle, before self-admin0.50.51.8-1.0-0.4-1.3-1.3-1.0-0.3-0.80.4-0.40.3-0.4-0.20.20.2
Time to tail flick, vehicle, after self-admin0.00.00.3-0.1-0.10.00.10.1-0.50.00.2-0.20.00.0-0.10.1-0.1
Time to tail flick, test, before self-admin4.14.26.0-1.9-1.3-2.3-2.4-2.5-2.1-2.42.3-2.31.9-1.9-1.91.91.2
Time to tail flick, test, after self-admin0.60.72.8-1.4-1.7-0.9-1.1-0.7-0.8-0.60.6-0.6-0.10.10.0-0.00.4
Delta time to tail flick, vehicle, before/after SA0.10.10.40.2-0.30.60.50.5-0.60.30.0-0.0-0.30.30.2-0.2-0.1
Delta time to tail flick, test, before/after SA0.80.91.80.80.11.30.81.20.91.1-1.01.0-0.90.90.8-0.9-0.1
Tibia length0.71.93.80.00.2-0.7-1.1-1.5-0.3-1.51.4-1.41.9-1.8-1.91.91.5
Ambulatory time before self-admin0.10.10.7-0.4-0.5-0.2-0.4-0.3-0.9-0.1-0.00.0-0.20.20.1-0.2-0.1
Ambulatory time after self-admin1.31.53.51.40.91.61.91.50.91.6-1.21.2-0.90.90.8-0.8-0.8
Bone: tissue strength0.40.41.5-1.0-1.2-0.6-0.8-0.6-0.8-0.50.7-0.70.2-0.2-0.10.1-0.0
Total heroin consumption0.60.71.61.01.20.41.20.81.31.0-1.11.1-0.40.30.3-0.3-0.2
Bone: trabecular number0.50.82.2-1.5-1.4-1.2-0.8-0.8-1.0-1.10.8-0.80.1-0.1-0.10.1-0.2
Bone: trabecular spacing0.00.10.20.30.50.2-0.4-0.00.30.2-0.20.2-0.00.0-0.10.10.4
Bone: trabecular thickness0.10.10.50.1-0.70.40.60.4-0.50.00.2-0.2-0.10.10.1-0.1-0.1
Bone: trabecular tissue density2.63.811.33.42.72.82.62.01.92.3-1.81.8-0.20.2-0.00.00.3
Water consumed over 24 hours0.10.20.3-0.4-0.4-0.3-0.5-0.4-0.3-0.60.5-0.50.3-0.3-0.30.30.3
Number of responses in last shaping day0.10.10.2-0.0-0.10.40.30.40.20.10.0-0.0-0.30.30.3-0.3-0.4