Hub : Genes

Map2k7

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Map2k7 0.06 0.04 1.3e-03 0.02 0.03 0.02 0.01 5.9e-03 2.3e-04 9.1e-04 1.0e-02
2 IL gene expression Map2k7 0.17 0.12 5.3e-03 0.15 0.08 0.04 0.14 2.0e-04 4.8e-03 3.7e-02 4.1e-04
3 Liver gene expression Map2k7 0.05 0.03 1.7e-03 0.03 0.02 0.02 0.02 8.1e-04 3.0e-03 3.9e-03 1.6e-03
4 NAcc isoform ratio NM_001025425.2 0.03 0.02 3.8e-03 0.01 0.01 0.02 0.01 3.7e-02 2.4e-02 4.8e-03 5.3e-02
5 NAcc isoform ratio NM_001401207.1 0.04 0.03 1.4e-03 0.01 0.02 0.03 0.01 1.3e-02 5.1e-03 1.6e-04 6.8e-03
6 Brain gene expression Map2k7 0.06 0.04 3.4e-06 0.06 0.06 0.06 0.04 5.4e-06 1.7e-06 4.4e-06 1.3e-04
7 PL mRNA stability Map2k7 0.05 0.04 7.5e-03 0 0 0 0.01 1.8e-01 1.6e-01 1.2e-01 4.7e-02
8 PL gene expression Map2k7 0.05 0.03 2.5e-05 0.04 0.05 0.04 0.02 5.4e-05 8.3e-06 2.7e-05 1.7e-03
9 NAcc intron excision ratio chr12_2593325_2595939 0.03 0.02 1.2e-03 0.02 0.02 0.02 0.01 1.1e-03 3.8e-03 5.0e-03 1.3e-02
10 pVTA gene expression Map2k7 0.12 0.08 2.4e-04 0.06 0.05 0.04 0.05 2.1e-03 3.4e-03 6.4e-03 3.7e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density2.44.111.8-3.42.52.41.8-1.8-2.4-0.8-1.70.60.7
Area under the delay curve0.40.41.50.5-0.00.1-0.60.3-0.60.6-0.61.01.2
BMI with tail1.23.87.2-2.62.12.01.9-2.2-2.7-1.4-1.61.01.4
BMI without tail1.73.48.5-2.71.81.82.7-2.9-1.6-1.3-0.8-0.10.4
Body weight4.719.957.2-7.64.94.85.3-5.5-4.3-3.5-2.2-0.60.2
Weight adjusted by age0.50.52.0-0.70.30.21.3-1.40.2-0.60.3-0.5-0.5
Bone surface2.74.713.1-3.62.52.52.1-2.1-2.6-1.4-1.70.60.5
Bone volume2.33.89.7-3.12.42.41.2-1.3-2.7-0.9-1.91.11.0
Breakpoint value in progressive ratio session2.12.33.2-1.41.71.8-1.11.2-1.81.3-1.81.71.5
Number of licking bursts5.26.210.61.1-2.2-2.22.4-2.12.9-2.02.8-3.2-3.3
Context. condit. distance diff. score4.65.511.4-3.43.13.30.3-0.4-3.00.7-2.61.81.9
Locomotion velocity, session 10.20.20.50.20.10.2-0.70.7-0.10.6-0.30.50.5
Locomotion distance, session 10.30.41.11.1-0.5-0.5-0.70.50.40.80.20.20.6
Locomotion velocity, session 20.30.40.80.8-0.8-0.70.2-0.30.9-0.10.8-0.7-0.3
Locomotion distance, session 20.40.61.21.1-0.7-0.6-0.90.91.11.00.5-0.20.1
Locomotion velocity, session 31.01.21.9-1.21.31.4-0.40.2-1.40.6-1.21.01.3
Locomotion distance, session 30.10.10.3-0.40.40.40.0-0.1-0.30.5-0.40.30.4
Stereotopy head waving bouts, day 30.60.72.4-1.60.91.00.9-0.9-0.5-0.7-0.3-0.30.1
Stereotopy head waving duration, day 30.10.10.50.2-0.3-0.2-0.1-0.00.1-0.70.3-0.20.2
Locomotion velocity, session 70.10.10.40.7-0.5-0.4-0.30.10.2-0.20.20.10.4
Locomotion distance, session 70.10.20.4-0.10.30.4-0.50.4-0.30.7-0.50.50.5
Stereotopy head waving bouts, day 70.50.51.80.40.10.2-1.41.3-0.10.7-0.30.60.8
Stereotopy head waving duration, day 70.30.31.00.8-0.4-0.4-1.01.00.40.30.20.10.2
Locomotion velocity, session 80.00.00.2-0.2-0.00.1-0.10.0-0.1-0.40.1-0.20.1
Locomotion distance, session 80.81.22.9-1.71.41.70.4-0.4-1.40.1-1.10.60.9
Degree of sensitization distance0.60.61.41.2-1.0-0.9-0.70.80.8-0.00.7-0.3-0.5
Degree of sensitization stereotypy0.30.31.10.30.10.2-1.11.0-0.20.5-0.30.60.6
Conditioned locomotion0.60.71.2-0.60.80.8-0.40.4-1.00.7-0.90.91.1
Cocaine response after cond. corrected0.70.83.70.6-0.9-1.00.6-0.70.0-1.90.7-0.4-0.5
Cocaine response after cond. not corrected0.40.41.5-0.20.30.1-0.40.2-1.1-1.2-0.50.80.6
Cocaine response before conditioning4.55.57.3-1.92.72.7-2.12.1-2.41.8-2.72.52.4
Saline control response0.60.81.6-1.30.50.61.2-0.90.70.50.2-1.0-1.2
Bone: connectivity density2.94.614.2-3.82.52.42.4-2.4-2.2-1.0-1.50.20.2
Bone: cortical apparent density0.30.41.10.7-0.6-0.6-1.00.90.0-0.50.20.10.5
Bone: cortical area1.52.35.2-2.31.82.00.9-1.1-2.0-0.2-1.50.90.9
Bone: cortical porosity0.00.00.1-0.00.00.1-0.10.20.30.30.1-0.1-0.2
Bone: cortical porosity0.30.31.30.10.30.4-0.70.80.11.1-0.30.50.1
Bone: cortical thickness1.01.63.8-1.91.41.51.3-1.4-1.6-0.5-1.10.50.5
Bone: cortical thickness0.30.31.4-1.20.90.70.4-0.2-0.3-0.1-0.3-0.2-0.4
Bone: cortical tissue density0.30.41.10.8-0.7-0.7-1.11.00.1-0.50.30.10.5
Condit. Reinf. active minus inactive responses0.30.30.80.40.00.0-0.80.9-0.40.4-0.50.90.4
Condit. Reinf. active-inactive response ratio0.40.41.0-0.00.30.3-0.90.9-0.80.1-0.71.00.6
Condit. Reinf. active responses0.70.82.20.00.60.6-1.01.0-0.61.5-0.91.20.8
Condit. Reinf. inactive responses0.80.94.50.10.50.6-1.11.0-0.12.1-0.70.91.0
Incentive salience index mean1.01.22.4-0.00.70.7-1.21.3-0.91.5-1.11.41.0
Condit. Reinf. lever presses1.52.14.6-0.61.31.3-1.31.4-1.22.1-1.61.71.4
Condit. Reinf. active minus inactive responses0.30.31.3-1.10.80.80.4-0.1-0.4-0.0-0.4-0.1-0.5
Condit. Reinf. active-inactive response ratio0.10.10.6-0.20.1-0.00.4-0.20.30.10.1-0.3-0.8
Condit. Reinf. active responses1.11.63.5-1.91.81.7-0.40.7-1.40.5-1.50.90.4
Condit. Reinf. inactive responses1.41.72.6-1.51.61.6-1.11.3-1.40.7-1.51.21.0
Condit. Reinf. lever presses1.92.64.0-1.72.02.0-1.01.1-1.91.1-1.91.61.5
Condit. Reinf. lever reinforcers received0.91.32.5-1.51.61.5-0.60.8-1.20.7-1.30.90.4
Conditioned reinforcement - actives1.91.95.6-1.81.01.12.4-2.2-0.1-0.40.1-1.2-1.2
Conditioned reinforcement - inactives0.70.71.60.0-0.3-0.31.2-1.00.9-0.40.8-1.3-1.3
Conditioned locomotion1.41.65.1-2.31.91.81.0-0.7-1.00.9-1.10.10.1
Patch foraging indifference point 0 sec0.00.10.2-0.30.20.2-0.40.4-0.1-0.1-0.10.00.1
Patch foraging indifference point AUC0.10.10.6-0.80.20.30.3-0.1-0.0-0.2-0.0-0.4-0.6
Delay disc. indifference point, 0s delay0.30.42.90.3-0.6-0.4-0.1-0.1-0.4-1.70.30.00.3
Delay disc. indifference point, 16s delay0.10.10.30.4-0.3-0.3-0.1-0.1-0.10.4-0.10.20.5
Delay disc. indifference point, 2s delay2.12.35.20.30.70.6-2.01.8-1.50.9-1.52.32.1
Delay disc. indifference point, 24s delay0.30.31.01.0-0.9-0.8-0.20.20.50.30.5-0.3-0.0
Delay disc. indifference point, 4s delay1.31.42.80.20.40.6-1.71.6-1.10.8-1.11.61.7
Delay disc. indifference point, 8s delay0.40.41.60.20.20.4-0.1-0.1-0.41.3-0.60.91.1
Indifference point function ln k0.20.20.6-0.20.30.10.7-0.80.60.80.1-0.2-0.4
Indifference point function log k0.20.20.6-0.20.30.10.7-0.80.60.80.1-0.2-0.4
Patch foraging total patch changes 0 sec0.10.10.3-0.30.30.3-0.50.6-0.10.2-0.20.10.1
Patch foraging total patch changes 12 sec0.10.10.3-0.60.20.4-0.40.5-0.4-0.1-0.30.10.3
Patch foraging total patch changes 18 sec0.20.30.90.0-0.5-0.3-0.30.60.5-0.50.4-0.6-0.9
Patch foraging total patch changes 24 sec1.21.54.7-0.61.01.1-1.92.2-0.51.3-1.00.80.6
Patch foraging total patch changes 6 sec0.20.30.7-0.80.60.7-0.60.7-0.4-0.2-0.50.20.4
Patch foraging time to switch 0 sec1.11.74.42.1-2.0-1.7-0.80.50.2-1.80.90.10.6
Patch foraging water rate 0 sec1.21.96.1-2.52.11.81.2-0.8-0.31.3-0.8-0.4-0.7
Patch foraging water rate 12 sec0.61.03.9-1.11.31.3-0.10.1-0.22.0-0.90.50.3
Patch foraging water rate 18 sec1.21.66.7-0.61.41.3-1.00.9-0.32.6-1.21.01.1
Patch foraging water rate 24 sec1.01.43.7-1.91.91.60.5-0.3-0.31.5-0.90.1-0.0
Patch foraging water rate 6 sec1.72.45.3-1.82.32.1-0.30.3-1.32.1-1.71.21.0
Seeking ratio, delayed vs. immediate footshock3.13.56.92.6-2.6-2.60.3-0.12.2-0.72.0-1.3-1.9
Distance traveled before self-admin0.50.51.30.40.40.2-1.01.1-0.21.0-0.50.90.8
Distance traveled after self-admin0.10.20.4-0.40.70.5-0.00.2-0.40.5-0.50.30.2
Extensor digitorum longus weight2.811.030.2-5.54.44.52.9-2.8-3.60.2-3.01.21.0
Bone: elastic displacement0.10.10.5-0.70.40.40.4-0.5-0.0-0.10.1-0.4-0.0
Bone: elastic work1.51.96.5-2.51.91.91.3-1.4-1.1-0.3-0.9-0.20.4
Bone: endosteal estimation0.20.51.6-1.30.70.80.9-0.70.0-0.40.0-0.7-0.7
Bone: endosteal perimeter1.02.15.3-2.32.12.20.2-0.1-1.50.5-1.60.90.7
Epididymis fat weight1.63.66.0-1.62.11.9-1.41.4-2.21.3-2.22.12.4
Delta time in closed arm before/after self-admin0.20.20.5-0.40.40.3-0.30.70.00.5-0.30.2-0.2
Delta time in open arm before/after self-admin0.70.61.91.4-0.7-0.5-1.10.6-0.10.4-0.20.91.0
Diff in mean of infusions in LGA sessions1.31.42.4-1.11.41.6-0.60.6-1.11.5-1.31.11.2
Delay discount exponential model param0.70.72.0-0.4-0.2-0.30.8-0.60.8-1.00.9-1.3-1.4
Extinction: sum of active levers before priming0.90.92.00.40.20.3-1.41.4-0.71.0-0.81.11.1
Active lever presses in extinction session 60.40.40.9-0.80.80.6-0.10.1-0.90.0-0.70.50.5
Bone: final force0.81.22.9-1.70.80.91.7-1.6-0.4-0.90.0-0.8-0.8
Bone: final moment0.61.02.4-1.40.60.71.6-1.5-0.2-1.00.2-0.9-0.8
Food consumed during 24 hour testing period0.70.82.20.2-0.5-0.51.3-1.11.0-0.30.8-0.9-1.5
Glucose0.30.51.01.0-1.0-0.9-0.50.40.3-0.90.7-0.30.1
Heart weight0.30.52.5-0.00.20.10.10.21.11.60.2-0.6-0.8
Delay discount hyperbolic model param0.70.71.8-0.5-0.1-0.20.9-0.60.7-0.90.8-1.3-1.4
Intermittent access intake day 1-15 change1.31.33.9-0.60.10.22.0-1.90.6-0.70.8-1.4-1.4
Intermittent access intake escalation0.90.92.9-1.00.60.71.7-1.60.2-0.20.2-0.9-0.9
Intermittent access intake escalation 20.10.10.3-0.20.30.30.6-0.50.20.20.2-0.4-0.5
Intermitt. access day 1 inactive lever presses0.60.61.90.1-0.2-0.30.9-0.61.0-0.20.7-1.1-1.4
Intermitt. access day 15 inactive lever presses0.80.92.50.9-1.0-1.00.7-0.90.6-1.61.0-0.8-0.6
Intermitt. access escalation Index1.00.91.8-0.30.90.8-1.11.1-0.41.3-1.01.00.9
Intermittent access day 1 total infusions0.50.61.80.30.40.5-0.80.7-0.41.4-0.71.00.9
Intermittent access day 15 total infusions0.30.31.0-0.50.81.00.5-0.5-0.20.8-0.40.10.2
Intermittent access terminal intake (last 3 days)0.10.10.40.20.10.30.6-0.60.00.4-0.10.10.1
Intermittent access total infusions0.30.30.70.10.40.6-0.50.4-0.40.9-0.60.70.7
Intermittent access day 1 locomotion2.52.75.50.01.11.2-1.41.1-1.22.3-1.82.22.3
Intermittent access day 15 total locomotion2.62.87.4-1.22.02.1-0.60.6-1.12.7-1.81.61.5
Intermittent access total locomotion2.32.67.3-0.31.41.5-1.41.3-1.02.7-1.71.91.8
Intermittent access standard deviation0.91.02.00.1-0.6-0.51.4-1.40.5-1.30.9-1.1-1.1
Left kidney weight3.28.925.5-5.13.23.14.3-4.1-1.7-1.2-1.0-1.3-1.1
Right kidney weight2.36.518.9-4.32.52.63.7-3.5-1.4-1.6-0.6-1.3-0.8
Cocaine induced anxiety2.12.44.4-0.81.61.4-1.10.9-1.71.6-1.92.11.9
Post-drug Anxiety1.21.42.91.2-0.1-0.4-1.61.3-0.61.0-0.81.71.6
Baseline Anxiety1.81.96.12.5-2.1-2.0-1.10.91.0-0.81.2-0.2-0.1
Tail length2.47.224.2-4.93.23.23.2-3.2-2.0-1.1-1.2-0.8-0.2
Length with tail4.416.155.4-7.44.64.64.7-4.5-3.2-2.5-1.7-1.4-0.7
Length without tail3.16.922.5-4.73.13.22.4-2.4-3.0-1.8-1.70.00.5
Times rat made contact with spout0.30.41.1-0.60.00.01.0-0.80.60.10.4-0.7-1.0
Lifetime Intake0.10.10.30.6-0.2-0.0-0.2-0.0-0.20.3-0.10.40.5
Liver weight, left0.40.61.7-0.80.00.11.3-1.20.1-0.80.3-0.8-0.7
Liver weight, right1.82.98.9-3.02.12.21.9-1.7-1.6-0.3-1.30.20.2
Locomotor activity1.01.65.1-2.32.01.90.7-0.6-0.80.8-1.00.10.3
Locomotor testing distance0.30.51.8-1.30.90.90.7-0.6-0.10.0-0.2-0.3-0.1
Locomotor testing rearing0.00.10.1-0.20.40.3-0.30.20.0-0.3-0.20.30.2
Locomotion in novel chamber0.30.41.7-0.30.30.3-0.30.60.70.90.1-0.3-1.3
Locomotion in novel chamber post-restriction1.01.23.5-1.91.51.70.7-0.4-0.41.4-0.90.3-0.2
Fecal boli incidents, locomotor time 11.01.13.2-1.81.51.60.30.0-0.71.0-1.00.30.1
Change in fecal boli incidents, locomotor task1.41.42.61.4-1.6-1.50.5-0.90.9-1.51.3-0.8-0.3
Time >=10cm from walls, locomotor time 11.31.33.20.20.30.4-1.71.8-1.00.5-1.01.51.4
Bouts of movement, locomotor time 10.40.41.7-1.30.70.90.6-0.3-0.30.1-0.3-0.3-0.5
Total resting periods, locomotor time 10.40.41.7-1.30.81.00.3-0.1-0.40.2-0.4-0.1-0.4
Rest time, locomotor task time 10.60.72.0-1.41.31.2-0.30.4-0.9-0.1-0.70.30.6
Distance moved, locomotor task time 10.20.30.70.8-0.6-0.8-0.40.30.60.50.3-0.1-0.2
Vertical activity count, locomotor time 10.30.31.10.1-0.1-0.41.0-1.00.30.40.1-0.4-0.6
Time >=10cm from walls, locomotor time 21.71.73.3-1.31.31.6-0.91.0-1.8-0.3-1.41.31.7
Bouts of movement, locomotor time 21.41.53.5-1.91.81.80.5-0.4-1.30.8-1.30.70.6
Total resting periods, locomotor time 21.11.23.0-1.71.61.70.6-0.5-1.20.5-1.10.50.5
Rest time, locomotor task time 20.60.71.5-0.50.80.9-0.90.8-0.70.8-0.80.91.2
Distance moved, locomotor task time 21.41.72.80.9-1.4-1.50.7-0.51.5-1.11.6-1.7-1.5
Vertical activity count, locomotor time 21.41.53.3-0.5-0.3-0.41.8-1.60.9-1.01.0-1.8-1.6
Light reinforcement 10.30.61.30.8-0.2-0.0-1.10.9-0.21.0-0.40.81.0
Light reinforcement 20.50.71.51.1-1.2-0.90.2-0.31.1-0.31.0-0.8-0.7
Bone: marrow area0.30.51.6-1.30.60.80.9-0.70.1-0.40.1-0.7-0.8
Bone: maximum diameter0.91.74.4-2.11.61.81.2-1.3-1.4-0.3-1.00.40.3
Bone: maximum force0.71.24.8-2.21.41.50.9-0.8-0.9-0.5-0.6-0.2-0.3
Bone: maximum moment0.50.93.6-1.91.21.30.9-0.7-0.7-0.6-0.4-0.3-0.3
Mean time between licks in bursts0.40.51.41.2-0.6-0.7-1.11.00.50.50.10.40.6
Mean num. licks in bursts2.02.43.6-1.11.51.6-1.21.0-1.71.5-1.81.91.8
Cd content in liver1.01.12.81.2-0.9-0.8-1.01.21.41.70.5-0.2-0.3
Co content in liver0.81.02.80.3-0.7-0.60.9-0.71.4-0.21.1-1.3-1.7
Cu content in liver0.40.41.2-0.50.80.6-0.20.4-0.51.1-0.80.70.3
Fe content in liver4.85.810.4-3.13.23.00.3-0.4-2.91.7-2.92.22.1
K content in liver0.30.30.6-0.30.60.4-0.20.2-0.80.1-0.70.80.4
Mg content in liver0.10.10.3-0.30.1-0.10.5-0.50.0-0.30.1-0.2-0.4
Mn content in liver1.21.42.41.4-1.5-1.60.2-0.11.4-0.71.4-1.1-1.3
Na content in liver0.30.30.7-0.70.60.6-0.20.1-0.7-0.0-0.60.50.8
Rb content in liver0.81.02.40.80.2-0.1-1.41.2-0.71.0-0.91.51.1
Se content in liver4.04.910.0-2.22.62.3-0.80.7-3.20.6-2.72.62.5
Sr content in liver1.81.63.20.6-1.3-0.91.1-1.11.3-1.41.6-1.8-1.2
Zn content in liver1.01.13.2-1.20.40.41.8-1.7-0.1-1.10.3-1.1-1.1
Bone: minimum diameter0.00.10.30.1-0.1-0.10.2-0.20.3-0.50.2-0.3-0.4
Time in familiar zone, hab. session 10.60.51.20.8-1.0-0.90.2-0.30.6-1.10.8-0.5-0.5
Time in novel zone, hab. session 10.10.10.4-0.70.60.60.00.0-0.4-0.1-0.30.00.1
Total zone transitions, hab. session 10.60.92.60.8-0.1-0.0-1.51.6-0.01.5-0.40.80.4
Total locomotion distance, hab. session 11.01.42.10.10.70.8-1.51.4-1.21.4-1.21.41.4
Locomotion velocity, hab. session 11.21.73.20.50.50.6-1.81.7-0.91.8-1.11.51.6
Time in familiar zone, hab. session 20.10.10.40.1-0.2-0.2-0.0-0.0-0.3-0.60.00.10.1
Time in novel zone, hab. session 20.20.20.60.20.10.1-0.80.70.20.6-0.10.20.4
Total zone transitions, hab. session 20.50.71.20.3-0.6-0.50.9-0.91.0-0.40.9-1.1-1.0
Total locomotion distance, hab. session 20.00.10.20.4-0.3-0.2-0.20.10.30.20.2-0.1-0.0
Locomotion velocity, hab. session 20.10.10.30.6-0.4-0.4-0.10.10.50.20.4-0.3-0.3
Novel to familiar place preference ratio0.50.61.10.7-0.8-0.90.2-0.11.0-0.51.0-0.9-0.7
Novelty place preference0.60.61.30.9-0.9-1.0-0.10.21.1-0.31.0-0.8-0.6
Time in novel zone, NPP test0.40.40.90.7-0.7-0.8-0.10.10.9-0.50.9-0.8-0.5
Total zone transitions, NPP test0.10.10.2-0.30.40.4-0.10.1-0.10.5-0.30.10.1
Total locomotion distance, NPP test1.52.13.4-0.91.41.5-1.31.1-1.51.3-1.61.61.8
Locomotion velocity, NPP test1.31.93.0-1.01.51.6-1.00.9-1.31.7-1.61.51.5
Intraocular pressure1.52.05.1-2.32.11.80.5-0.3-1.60.8-1.60.90.7
Delta distance traveled before/after self-admin0.50.51.3-0.2-0.2-0.11.1-1.10.4-0.60.5-0.9-0.9
Delta ambulatory time before/after self-admin0.10.20.40.1-0.2-0.20.5-0.60.3-0.40.3-0.5-0.5
Parametrial fat weight0.91.83.10.8-1.5-1.40.8-0.91.2-1.81.6-1.6-1.5
Pavlov. Cond. lever latency1.21.55.0-1.10.20.22.1-2.20.2-1.10.5-1.2-0.9
Pavlov. Cond. magazine entry latency0.20.20.6-0.70.60.80.4-0.4-0.30.2-0.40.20.3
Pavlov. Cond. change in total contacts0.50.51.30.30.10.2-1.11.1-0.60.2-0.61.00.8
Pavlov. Cond. index score0.50.61.1-0.30.70.8-0.70.7-0.80.7-0.91.01.0
Pavlov. Cond. latency score0.60.71.3-0.10.60.7-1.01.0-0.80.8-0.91.21.0
Pavlov. Cond. lever contacts1.11.33.80.80.10.1-1.92.0-0.41.1-0.71.21.0
Pavlov. Cond. magazine entry number0.91.22.51.3-1.5-1.6-0.20.21.0-1.01.2-1.0-0.9
Pavlov. Cond. intertrial magazine entries0.40.51.21.1-0.7-0.7-0.80.80.91.10.4-0.10.0
Pavlov. Cond. lever-magazine prob. diff.0.40.50.9-0.30.70.8-0.60.5-0.80.6-0.81.01.0
Pavlov. Cond. response bias0.80.91.5-0.81.11.2-0.40.5-1.01.0-1.21.11.0
Pavlov. Cond. lever latency1.41.92.40.7-1.3-1.41.4-1.41.2-1.51.5-1.5-1.4
Pavlov. Cond. magazine entry latency1.21.42.80.40.50.6-1.71.6-0.91.5-1.11.51.3
Pavlov. Cond. change in total contacts0.50.72.0-0.40.90.9-0.50.4-0.61.4-1.00.90.8
Pavlov. Cond. index score1.41.93.5-0.21.11.1-1.61.6-1.11.9-1.41.61.3
Pavlov. Cond. latency score1.51.83.0-0.21.01.1-1.61.6-1.11.7-1.41.71.3
Pavlov. Cond. lever contacts2.23.04.2-0.91.71.7-1.71.7-1.81.7-2.02.11.9
Pavlov. Cond. magazine entry number0.91.22.7-0.6-0.3-0.41.6-1.60.5-1.50.8-1.3-0.9
Pavlov. Cond. intertrial magazine entries0.20.20.4-0.60.10.00.6-0.50.4-0.50.3-0.6-0.6
Pavlov. Cond. lever-magazine prob. diff.1.31.63.7-0.10.91.0-1.51.5-0.91.9-1.31.51.2
Pavlov. Cond. response bias2.94.05.8-0.71.81.8-2.12.1-1.92.3-2.22.42.1
Time in closed arm before self-admin0.60.71.6-0.70.10.51.3-1.20.4-0.20.5-1.3-1.0
Time in closed arm after self-admin0.50.51.2-1.10.90.90.00.50.20.9-0.2-0.5-0.8
Time in open arm before self-admin0.10.10.6-0.30.30.10.8-0.5-0.00.0-0.10.1-0.2
Time in open arm after self-admin0.20.20.60.3-0.3-0.20.4-0.8-0.4-0.5-0.10.50.7
Bone: periosteal estimation0.71.54.8-2.21.51.71.3-1.2-1.1-0.5-0.8-0.0-0.1
Bone: periosteal perimeter2.13.67.4-2.42.52.7-0.10.1-2.21.1-2.21.71.5
Bone: post-yield work1.01.42.1-1.31.51.4-0.91.1-1.40.5-1.41.10.8
Progressive ratio test 1 active lever presses0.50.51.6-0.20.00.11.3-1.30.3-0.40.4-0.8-0.9
Progressive ratio test 1 breakpoint0.70.72.1-0.1-0.2-0.11.4-1.40.5-0.70.7-1.1-1.0
Progressive ratio test 1 inactive lever presses0.50.51.6-0.50.30.21.0-0.60.70.10.5-1.1-1.3
Progressive ratio test 2 active lever presses0.70.71.5-1.11.11.21.2-1.1-0.20.6-0.3-0.4-0.4
Progressive ratio test 2 breakpoint0.30.40.7-0.60.70.80.8-0.60.10.7-0.1-0.4-0.5
Progressive ratio test 2 inactive lever presses1.01.23.3-1.81.51.71.1-0.80.10.7-0.4-0.6-0.7
Incentive Sensitization - Responses0.20.20.8-0.30.60.70.10.0-0.20.9-0.50.40.2
Incentive Sensitization - Breakpoint0.30.31.1-0.40.80.8-0.10.2-0.21.0-0.60.50.3
Sum of active levers in priming session hrs 5-60.70.71.70.10.10.3-1.20.9-1.3-0.1-0.70.91.3
Progressive ratio0.70.81.91.4-1.1-1.20.3-0.31.2-0.21.0-0.5-0.9
Food seeking constrained by brief footshock0.30.41.01.0-0.9-0.90.1-0.10.7-0.00.6-0.2-0.9
Seeking ratio, punishment vs. effort0.30.41.2-1.10.70.80.3-0.3-0.8-0.0-0.60.10.2
Retroperitoneal fat weight1.23.811.60.30.70.7-2.52.0-2.30.5-1.82.63.4
Reaction time number correct0.30.51.4-0.80.60.31.2-1.00.20.30.1-0.6-1.0
Reaction time mean minus median3.24.26.2-1.72.22.4-1.31.1-2.21.8-2.52.52.2
Reaction time mean minus median AUC1.82.34.2-0.71.31.6-1.61.5-1.02.0-1.71.81.6
Reaction time num false alarms1.41.83.6-0.61.31.1-1.81.9-0.91.4-1.31.51.4
Reaction time num false alarms AUC2.33.25.6-1.11.71.7-2.22.4-1.31.7-1.81.81.8
Reaction time trials correct on left0.30.51.4-0.80.60.31.2-1.00.20.30.1-0.6-1.0
Reaction time trials on left0.30.51.4-0.80.60.31.2-1.00.20.30.0-0.6-0.9
Reaction time mean0.60.82.41.5-0.8-0.6-1.00.60.10.5-0.11.01.3
Reaction time mean AUC0.70.92.31.4-0.7-0.4-1.20.9-0.10.6-0.31.21.5
Median of all reaction times1.11.46.12.5-1.7-1.5-0.80.40.70.10.60.50.9
Reaction time omissions0.81.13.20.30.30.4-1.20.9-0.41.3-0.91.51.8
Reaction time false alarm rate2.33.25.9-0.81.41.5-2.42.4-1.41.4-1.82.02.1
Reaction time premature initiation rate0.10.10.3-0.10.30.4-0.30.2-0.20.5-0.40.30.1
Reaction time premature initiations0.10.20.4-0.40.50.50.3-0.4-0.10.6-0.30.1-0.3
Std. dev. reaction times1.21.73.4-0.30.91.1-1.31.1-1.21.3-1.51.81.7
Reaction time trials completed0.30.51.4-0.80.60.31.2-1.00.20.30.0-0.6-0.9
Reaction time trials AUC0.20.30.8-0.70.60.40.9-0.70.10.6-0.1-0.4-0.7
Run reversals in cocaine runway, females0.20.20.60.20.10.1-0.80.7-0.30.2-0.20.40.4
Run reversals in cocaine runway, males0.30.31.00.2-0.1-0.2-0.00.21.00.90.4-0.6-0.7
Latency to leave start box in cocaine runway0.40.40.90.7-0.9-0.70.0-0.20.5-0.90.8-0.70.0
Latency to leave start box in cocaine runway, F1.11.22.80.6-1.2-1.00.9-1.00.7-1.71.4-1.4-0.6
Latency to leave start box in cocaine runway, M1.21.13.0-0.10.70.9-1.31.3-0.41.7-1.01.11.1
Std. dev. time between licks in bursts0.70.81.6-1.01.31.1-0.20.2-0.71.2-1.10.80.8
Total sessions with >9 infusions0.10.10.2-0.20.30.40.2-0.4-0.30.3-0.20.20.4
Short access day 1 total inactive lever presses0.40.51.10.5-0.5-0.60.3-0.11.1-0.40.9-0.9-1.0
Short access day 10 total inactive lever presses0.80.92.2-1.00.30.21.5-1.30.2-1.10.4-1.0-1.1
Short access day 1 total infusions0.70.82.51.6-1.4-1.3-0.40.10.5-0.60.9-0.30.0
Short access day 10 total infusions0.20.20.60.6-0.2-0.0-0.2-0.1-0.30.4-0.30.70.8
Short access total infusions0.80.91.81.3-1.3-1.20.6-0.90.4-1.00.9-0.5-0.2
Short access day 1 locomotion0.80.93.00.9-0.2-0.2-1.71.70.11.0-0.20.70.6
Short access day 10 total locomotion0.30.41.20.30.20.20.0-0.3-0.21.1-0.50.91.0
Short access total locomotion0.40.41.30.8-0.2-0.2-0.50.2-0.40.8-0.41.01.1
One hour access (0.3 mA shock)0.30.31.3-0.10.30.40.10.30.91.10.2-0.5-0.8
Compulsive drug intake1.61.64.62.1-1.5-1.6-1.41.41.40.40.9-0.2-0.2
One hour access (shock baseline)1.11.33.3-1.81.81.80.10.1-0.71.1-1.10.40.1
Social response proportion1.21.34.0-1.60.80.62.0-1.8-0.3-0.70.0-0.9-0.9
Social responses1.31.64.6-2.12.11.80.6-0.4-1.10.8-1.20.40.4
Social time1.11.43.21.8-1.1-1.3-1.81.71.00.90.50.2-0.1
Soleus weight1.33.79.1-3.02.62.61.3-1.3-2.30.2-2.01.10.9
Bone: stiffness0.40.72.0-1.41.21.3-0.10.3-0.80.4-0.90.40.1
Tibialis anterior weight3.211.131.2-5.64.34.33.0-3.0-3.8-0.5-2.91.11.0
Time to tail flick, vehicle, before self-admin0.40.41.21.1-1.1-1.00.4-0.60.2-0.20.4-0.10.3
Time to tail flick, vehicle, after self-admin0.00.10.20.40.0-0.10.0-0.10.00.4-0.20.30.2
Time to tail flick, test, before self-admin0.60.61.7-0.60.10.11.3-1.30.1-1.00.3-0.8-0.5
Time to tail flick, test, after self-admin0.30.31.00.2-0.3-0.20.8-1.0-0.5-0.90.1-0.10.3
Delta time to tail flick, vehicle, before/after SA0.20.20.70.10.40.3-0.80.8-0.10.6-0.40.40.2
Delta time to tail flick, test, before/after SA0.30.20.70.20.00.2-0.40.2-0.70.3-0.50.80.8
Tibia length2.77.723.4-1.7-0.2-0.34.8-4.80.5-3.21.5-2.7-2.7
Ambulatory time before self-admin2.22.23.4-0.61.41.3-1.41.6-1.31.9-1.61.81.7
Ambulatory time after self-admin0.80.91.3-0.71.11.1-0.60.6-1.00.9-1.11.01.0
Bone: tissue strength0.50.51.00.4-0.8-0.70.0-0.00.7-1.00.9-0.9-0.5
Total heroin consumption3.03.57.10.40.90.9-2.72.5-1.32.3-1.82.42.1
Bone: trabecular number2.03.19.0-3.02.01.91.9-1.9-2.0-1.1-1.20.30.3
Bone: trabecular spacing1.51.95.62.4-1.4-1.4-1.71.71.31.20.60.20.1
Bone: trabecular thickness3.84.612.0-3.52.92.81.0-1.0-2.8-0.3-2.11.21.3
Bone: trabecular tissue density1.31.82.6-0.71.21.4-1.61.6-1.31.2-1.41.41.6
Water consumed over 24 hours1.21.53.9-0.9-0.1-0.02.0-1.81.0-0.40.9-1.5-1.7
Number of responses in last shaping day0.00.00.1-0.00.0-0.0-0.00.00.40.30.2-0.3-0.3