Hub : Genes

Nrxn2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 OFC intron excision ratio chr1_203825787_203827758 0.2 0.12 4.1e-04 0.17 0.14 0.1 0.15 7.9e-05 3.9e-04 2.6e-03 2.0e-04
2 BLA mRNA stability Nrxn2 0.12 0.08 2.9e-04 0.04 0.04 0.03 0.03 4.2e-03 5.1e-03 1.2e-02 1.2e-02
3 Brain gene expression Nrxn2 0.07 0.04 4.9e-07 0.06 0.06 0.05 0.05 1.6e-06 5.1e-06 1.2e-05 1.1e-05
4 PL alternative TSS XM_039110749.1 0.04 0.03 4.2e-05 0.04 0.05 0.03 0.04 1.2e-05 5.8e-06 1.3e-04 1.7e-05
5 NAcc mRNA stability Nrxn2 0.05 0.03 3.4e-05 0.02 0.04 0.04 0.04 1.5e-03 2.8e-05 5.6e-05 5.7e-05
6 Eye intron excision ratio chr1_203752084_203756693 0.29 0.16 5.5e-03 0.11 0.12 0.09 0.1 8.2e-03 5.9e-03 1.9e-02 1.1e-02
7 OFC intron excision ratio chr1_203827836_203840363 0.32 0.17 1.3e-05 0.2 0.19 0.18 0.21 1.7e-05 3.2e-05 4.0e-05 1.2e-05
8 BLA intron excision ratio chr1_203763525_203780407 0.05 0.04 2.1e-03 0.06 0.05 0.03 0.04 5.2e-04 1.6e-03 7.1e-03 2.1e-03
9 Brain mRNA stability Nrxn2 0.04 0.03 8.0e-05 0.04 0.04 0.04 0.04 6.6e-05 2.5e-04 1.2e-04 8.8e-05
10 NAcc gene expression Nrxn2 0.02 0.01 8.5e-03 0.01 0 0.01 0 1.9e-02 7.6e-02 6.2e-02 1.3e-01
11 BLA intron excision ratio chr1_203802213_203813559 0.07 0.06 4.5e-03 0.01 0.01 0 0.01 1.2e-01 5.7e-02 2.2e-01 1.3e-01
12 Brain alternative TSS XM_039110749.1 0.04 0.02 4.1e-04 0.03 0.04 0.04 0.03 6.9e-04 1.3e-04 2.9e-04 4.1e-04
13 OFC intron excision ratio chr1_203763525_203780407 0.3 0.15 3.1e-04 0.17 0.15 0.16 0.16 7.3e-05 1.7e-04 1.5e-04 1.6e-04
14 IL gene expression Nrxn2 0.24 0.12 1.8e-04 0.16 0.12 0.12 0.15 9.6e-05 8.4e-04 9.5e-04 2.4e-04
15 Liver gene expression Nrxn2 0.06 0.03 3.7e-06 0.04 0.04 0.05 0.04 3.4e-05 9.3e-06 1.5e-06 1.9e-05
16 Brain alternative TSS XM_008760061.3 0.04 0.02 9.1e-04 0.02 0.03 0.02 0.02 3.8e-03 2.2e-03 4.1e-03 2.4e-03
17 OFC gene expression Nrxn2 0.3 0.19 7.1e-04 0.15 0.09 0.15 0.14 2.0e-04 3.9e-03 1.9e-04 3.8e-04
18 Brain alternative TSS XM_017588666.2 0.04 0.02 7.3e-04 0.02 0.03 0.02 0.02 4.9e-03 2.1e-03 3.9e-03 2.3e-03
19 BLA gene expression Nrxn2 0.06 0.04 5.8e-03 0.03 0.04 0.04 0.04 1.1e-02 2.6e-03 2.9e-03 4.8e-03
20 PL gene expression Nrxn2 0.08 0.04 2.5e-09 0.09 0.08 0.09 0.08 7.6e-10 3.9e-09 5.9e-10 3.9e-09
21 Brain intron excision ratio chr1_203763525_203780407 0.04 0.03 1.5e-03 0.01 0.03 0.02 0.02 8.2e-02 1.3e-03 3.5e-03 9.6e-03
22 PL intron excision ratio chr1_203763525_203772110 0.03 0.02 8.3e-04 0.03 0.01 0.01 0.02 7.3e-04 7.5e-03 8.4e-03 5.8e-03
23 pVTA intron excision ratio chr1_203827836_203840363 0.12 0.08 5.2e-03 -0 -0.01 -0.01 -0.01 5.8e-01 9.6e-01 6.8e-01 7.5e-01
24 pVTA intron excision ratio chr1_203827836_203840945 0.12 0.07 6.0e-03 -0 -0.01 -0.01 0.07 5.1e-01 8.8e-01 8.4e-01 6.0e-04
25 PL intron excision ratio chr1_203763525_203780407 0.03 0.03 6.1e-03 0.01 0 0.01 0.01 2.5e-02 2.1e-01 6.9e-02 2.6e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25
Bone: apparent density0.50.83.50.80.8-0.8-1.4-1.5-0.50.20.4-0.4-0.4-1.6-0.00.5-0.61.2-0.1-0.7-0.11.2-1.2-1.4-0.5-0.5-0.71.9
Area under the delay curve0.20.21.2-0.0-0.1-0.1-0.10.0-0.1-0.20.2-0.2-0.2-0.1-0.10.3-0.2-1.00.1-1.10.10.40.1-0.5-0.40.70.71.0
BMI with tail3.110.129.72.72.7-3.1-4.4-4.3-2.51.82.9-2.9-2.9-4.7-1.42.9-2.53.41.2-3.11.04.3-3.7-4.7-3.2-0.2-0.45.5
BMI without tail2.24.58.81.51.6-2.2-2.5-2.2-1.91.52.6-2.6-2.6-2.6-1.42.5-1.71.81.3-2.21.22.8-1.9-3.0-2.30.90.52.9
Body weight3.514.822.74.04.1-4.3-4.7-4.5-3.93.73.9-3.9-3.9-4.8-3.24.0-3.83.82.9-3.32.84.6-4.3-4.8-4.2-0.1-0.24.0
Weight adjusted by age2.02.24.81.81.7-1.8-1.7-1.8-1.61.81.5-1.5-1.5-1.7-1.31.6-1.41.41.2-1.01.21.3-2.2-1.3-1.5-1.0-0.80.5
Bone surface3.56.215.12.92.8-2.8-3.6-3.9-2.22.02.0-2.0-2.0-3.8-1.31.8-1.92.81.0-1.40.92.6-3.4-2.8-2.0-2.2-2.22.8
Bone volume1.42.47.61.61.6-1.5-2.4-2.8-1.00.70.7-0.7-0.7-2.7-0.20.7-0.81.9-0.0-0.6-0.11.4-2.4-1.7-0.8-2.2-2.22.2
Breakpoint value in progressive ratio session2.42.64.21.91.9-1.9-2.0-2.0-1.81.61.7-1.7-1.7-1.9-1.51.5-1.51.61.4-1.61.41.5-1.9-1.5-1.5-1.2-1.00.4
Number of licking bursts0.20.20.40.70.6-0.6-0.6-0.6-0.40.40.6-0.6-0.6-0.5-0.30.3-0.40.50.3-0.30.30.3-0.4-0.3-0.5-0.5-0.50.1
Context. condit. distance diff. score1.21.42.7-1.6-1.61.51.41.41.3-1.4-0.80.80.81.31.2-1.11.2-1.5-1.11.1-1.1-1.01.31.01.10.90.70.1
Locomotion velocity, session 10.20.21.10.30.2-0.00.00.2-0.30.40.4-0.4-0.4-0.0-0.40.5-0.8-0.50.4-0.10.40.4-0.2-0.4-0.41.01.10.9
Locomotion distance, session 10.70.93.70.90.8-0.5-1.0-0.9-0.70.40.6-0.6-0.6-1.1-0.50.8-1.20.20.5-1.20.41.3-1.3-1.5-0.70.70.71.9
Locomotion velocity, session 22.63.14.62.01.9-1.8-2.1-2.0-1.81.61.7-1.7-1.7-2.0-1.51.8-2.01.81.5-1.91.42.1-1.9-2.1-1.70.00.11.5
Locomotion distance, session 20.81.12.61.10.9-0.7-1.1-0.8-0.90.60.7-0.7-0.7-0.9-0.91.0-1.40.50.9-1.60.81.4-1.1-1.4-1.00.80.81.5
Locomotion velocity, session 30.40.54.7-0.5-0.50.8-0.1-0.10.6-0.9-0.50.50.5-0.30.8-0.50.2-0.7-0.80.2-0.90.3-0.5-0.50.50.70.52.2
Locomotion distance, session 30.00.00.4-0.1-0.30.30.10.20.1-0.2-0.10.10.10.00.2-0.1-0.0-0.4-0.20.2-0.20.0-0.1-0.10.10.30.30.6
Stereotopy head waving bouts, day 30.60.73.4-1.0-0.81.00.30.30.8-1.0-0.70.70.7-0.01.0-0.60.5-1.0-1.00.6-1.10.2-0.1-0.30.61.00.71.8
Stereotopy head waving duration, day 30.60.71.3-1.1-0.91.10.60.51.0-1.1-0.90.90.90.41.1-0.90.9-0.9-1.10.8-1.1-0.40.30.30.90.40.20.7
Locomotion velocity, session 70.60.61.9-0.7-0.81.10.20.11.0-1.4-0.80.80.80.01.2-0.90.6-0.7-1.20.1-1.2-0.1-0.3-0.11.10.2-0.11.0
Locomotion distance, session 70.20.21.4-0.2-0.30.60.10.30.2-0.5-0.30.30.30.20.2-0.0-0.3-0.5-0.1-0.6-0.20.4-0.2-0.40.11.21.10.9
Stereotopy head waving bouts, day 70.40.41.5-0.3-0.30.4-0.1-0.40.7-0.7-0.10.10.1-0.30.9-0.90.8-0.1-1.00.6-1.0-0.4-0.00.30.9-1.1-1.20.5
Stereotopy head waving duration, day 70.91.12.61.21.2-1.1-1.5-1.6-0.80.61.1-1.1-1.1-1.5-0.50.5-0.61.20.3-0.90.30.9-1.1-1.0-0.6-1.2-1.21.0
Locomotion velocity, session 81.11.32.41.11.0-0.9-0.9-0.6-1.31.31.4-1.4-1.4-0.9-1.31.4-1.50.31.3-0.61.31.3-0.4-1.3-1.31.01.11.1
Locomotion distance, session 80.20.33.1-0.4-0.50.6-0.1-0.10.5-0.70.0-0.0-0.0-0.30.7-0.40.2-0.6-0.80.4-0.80.2-0.3-0.40.40.40.21.7
Degree of sensitization distance0.10.10.9-0.1-0.10.4-0.2-0.10.2-0.4-0.10.10.1-0.30.3-0.1-0.1-0.1-0.3-0.2-0.40.5-0.3-0.50.10.60.41.0
Degree of sensitization stereotypy0.50.52.30.80.8-0.6-1.0-1.3-0.30.20.6-0.6-0.6-1.1-0.0-0.1-0.10.8-0.1-0.3-0.10.3-0.7-0.40.0-1.5-1.50.6
Conditioned locomotion1.31.62.31.31.5-1.3-1.4-1.2-1.41.41.5-1.5-1.5-1.3-1.31.3-1.31.01.3-0.91.31.4-1.0-1.4-1.30.10.20.8
Cocaine response after cond. corrected1.11.22.2-1.4-1.31.41.31.51.1-1.1-1.21.21.21.20.9-0.80.8-1.4-0.80.7-0.8-0.61.30.60.81.51.30.4
Cocaine response after cond. not corrected0.80.91.7-1.3-1.21.11.01.20.9-0.9-1.11.11.10.90.8-0.60.7-1.1-0.70.7-0.7-0.41.00.40.51.31.10.5
Cocaine response before conditioning0.50.61.40.90.9-1.2-1.0-1.1-0.80.90.4-0.4-0.4-1.0-0.60.7-0.51.20.5-0.60.50.6-1.1-0.6-0.7-1.0-0.9-0.1
Saline control response3.85.07.02.32.4-2.5-2.3-2.0-2.62.62.5-2.5-2.5-2.1-2.42.7-2.42.02.3-2.02.32.5-1.9-2.4-2.50.40.60.8
Bone: connectivity density2.03.26.71.91.9-2.0-2.5-2.5-1.71.41.3-1.3-1.3-2.6-1.11.6-1.62.20.9-1.50.92.1-2.2-2.3-1.7-0.7-0.82.2
Bone: cortical apparent density0.30.41.80.50.6-0.5-0.10.1-0.70.60.7-0.7-0.70.3-1.00.6-0.60.11.0-1.41.00.2-0.0-0.0-0.60.20.4-1.2
Bone: cortical area0.50.81.91.01.0-1.0-1.2-1.4-0.80.90.9-0.9-0.9-1.3-0.50.6-0.51.00.30.10.30.7-1.0-0.8-0.7-1.1-1.10.7
Bone: cortical porosity0.10.10.40.20.4-0.1-0.4-0.3-0.1-0.10.5-0.5-0.5-0.2-0.10.1-0.20.50.1-0.70.10.4-0.2-0.3-0.1-0.1-0.2-0.2
Bone: cortical porosity0.50.61.10.80.9-0.7-0.9-0.8-0.70.51.0-1.0-1.0-0.7-0.70.7-0.81.00.7-1.10.70.9-0.6-0.8-0.7-0.0-0.0-0.0
Bone: cortical thickness2.33.86.32.02.2-2.2-1.6-1.2-2.42.52.3-2.3-2.3-1.2-2.52.4-2.11.52.5-1.72.51.7-1.0-1.5-2.30.30.7-0.5
Bone: cortical thickness0.81.02.40.80.7-0.7-0.20.1-1.21.20.8-0.8-0.8-0.0-1.51.3-1.30.11.5-0.91.50.8-0.3-0.7-1.21.31.5-0.1
Bone: cortical tissue density0.40.52.10.60.7-0.6-0.10.1-0.80.70.8-0.8-0.80.2-1.10.7-0.70.21.1-1.41.20.2-0.1-0.1-0.70.30.5-1.2
Condit. Reinf. active minus inactive responses0.30.31.00.50.4-0.4-0.3-0.2-0.40.31.0-1.0-1.0-0.2-0.40.5-0.60.30.5-1.00.40.5-0.3-0.4-0.40.20.3-0.1
Condit. Reinf. active-inactive response ratio0.10.20.80.10.1-0.20.10.2-0.20.20.7-0.7-0.70.3-0.40.3-0.20.00.4-0.80.4-0.00.10.1-0.20.10.2-0.9
Condit. Reinf. active responses0.10.10.20.20.1-0.0-0.3-0.30.1-0.20.4-0.4-0.4-0.30.20.0-0.10.4-0.2-0.4-0.20.3-0.5-0.30.1-0.1-0.20.2
Condit. Reinf. inactive responses0.30.31.0-0.1-0.30.4-0.3-0.40.6-0.7-0.60.60.6-0.50.9-0.60.30.3-1.00.5-1.00.1-0.5-0.20.6-0.4-0.60.9
Incentive salience index mean0.40.51.30.70.5-0.6-0.8-0.7-0.50.31.1-1.1-1.1-0.7-0.40.7-0.70.70.4-1.10.40.9-0.8-0.9-0.60.20.20.6
Condit. Reinf. lever presses0.40.51.30.70.6-0.7-1.0-1.1-0.40.40.6-0.6-0.6-1.2-0.10.5-0.51.00.0-0.4-0.00.9-1.2-0.9-0.5-0.4-0.51.0
Condit. Reinf. active minus inactive responses0.30.41.3-0.4-0.40.40.1-0.20.7-0.7-0.50.50.5-0.10.9-0.80.9-0.3-1.00.6-1.0-0.6-0.30.50.8-1.1-1.1-0.1
Condit. Reinf. active-inactive response ratio1.51.63.8-0.9-0.90.90.2-0.31.4-1.3-1.11.11.1-0.21.8-1.51.6-0.2-1.91.7-1.9-1.0-0.20.71.6-1.6-1.90.5
Condit. Reinf. active responses0.10.10.50.10.1-0.3-0.3-0.40.0-0.10.3-0.3-0.3-0.30.1-0.10.2-0.0-0.2-0.5-0.2-0.0-0.6-0.00.0-0.7-0.7-0.1
Condit. Reinf. inactive responses0.70.83.30.60.6-0.8-0.4-0.1-0.90.71.2-1.2-1.2-0.1-1.11.1-0.90.11.1-1.81.10.8-0.4-0.7-1.20.70.9-0.2
Condit. Reinf. lever presses1.52.15.21.61.7-1.7-2.0-2.3-1.31.31.2-1.2-1.2-2.2-0.80.9-0.81.40.6-0.70.61.2-2.1-1.3-1.1-1.8-1.70.9
Condit. Reinf. lever reinforcers received0.20.31.00.50.5-0.6-0.6-0.8-0.30.30.5-0.5-0.5-0.6-0.20.2-0.00.30.1-0.70.10.2-0.9-0.2-0.3-1.0-0.9-0.1
Conditioned reinforcement - actives0.90.93.0-0.4-0.40.60.3-0.10.8-0.6-1.01.01.00.11.0-1.10.8-0.9-1.11.4-1.1-1.0-0.70.91.0-1.7-1.7-0.4
Conditioned reinforcement - inactives6.37.110.8-2.8-2.82.72.62.13.0-2.8-2.82.82.82.32.9-3.13.2-2.9-2.92.7-2.8-3.31.83.22.7-1.6-1.6-1.5
Conditioned locomotion8.910.714.5-3.3-3.33.53.53.13.6-3.3-3.83.83.83.23.3-3.73.4-3.7-3.23.6-3.1-3.82.43.73.5-0.7-0.7-2.1
Patch foraging indifference point 0 sec0.00.10.1-0.3-0.10.20.30.20.3-0.3-0.00.00.00.30.3-0.30.4-0.2-0.20.2-0.2-0.30.00.30.4-0.1-0.1-0.4
Patch foraging indifference point AUC2.93.45.22.22.1-2.3-2.1-2.2-2.02.12.2-2.2-2.2-2.1-1.71.7-1.81.71.6-1.31.61.5-2.0-1.5-1.7-1.4-1.10.4
Delay disc. indifference point, 0s delay0.30.32.1-0.4-0.50.40.10.30.1-0.4-0.00.00.0-0.00.20.3-0.2-1.2-0.1-0.7-0.20.40.1-0.6-0.11.41.11.4
Delay disc. indifference point, 16s delay0.80.91.6-1.0-1.10.90.80.71.1-1.2-0.80.80.80.81.0-1.11.1-1.3-1.00.3-1.0-1.01.10.91.1-0.4-0.3-0.3
Delay disc. indifference point, 2s delay0.10.11.0-0.1-0.3-0.0-0.1-0.20.2-0.2-0.20.20.2-0.30.30.10.10.0-0.40.3-0.40.10.3-0.30.00.1-0.11.0
Delay disc. indifference point, 24s delay0.30.31.7-0.2-0.20.00.40.7-0.20.20.3-0.3-0.30.6-0.50.4-0.3-0.80.6-0.80.60.10.10.1-0.41.11.3-0.4
Delay disc. indifference point, 4s delay0.40.42.2-0.2-0.3-0.10.10.4-0.10.00.6-0.6-0.60.2-0.30.7-0.3-1.00.3-1.10.30.50.2-0.5-0.61.51.50.9
Delay disc. indifference point, 8s delay0.30.31.6-0.0-0.1-0.10.00.3-0.2-0.10.3-0.3-0.30.1-0.40.3-0.5-1.20.4-1.10.40.50.2-0.5-0.61.31.20.9
Indifference point function ln k6.59.014.4-3.8-3.63.73.63.83.2-3.3-3.13.13.13.52.7-2.72.9-3.3-2.42.4-2.4-2.53.72.52.62.52.2-0.6
Indifference point function log k6.59.014.4-3.8-3.63.73.63.83.2-3.3-3.13.13.13.52.7-2.72.9-3.3-2.42.4-2.4-2.53.72.52.62.52.2-0.6
Patch foraging total patch changes 0 sec0.00.10.3-0.2-0.10.20.40.50.1-0.10.1-0.1-0.10.5-0.0-0.10.1-0.20.10.10.1-0.20.20.30.10.30.4-0.5
Patch foraging total patch changes 12 sec3.95.07.42.72.5-2.6-2.5-2.4-2.52.32.4-2.4-2.4-2.3-2.22.2-2.42.22.1-2.42.12.1-2.5-2.1-2.4-0.8-0.60.9
Patch foraging total patch changes 18 sec0.60.81.70.90.8-1.2-1.1-1.2-0.80.81.1-1.1-1.1-1.1-0.50.8-0.51.30.5-0.50.50.7-1.2-0.7-0.7-0.9-0.80.0
Patch foraging total patch changes 24 sec2.32.84.91.91.8-2.0-1.6-1.5-1.92.02.2-2.2-2.2-1.5-1.81.7-1.61.41.7-1.11.71.4-1.8-1.3-2.0-0.6-0.20.3
Patch foraging total patch changes 6 sec0.81.22.01.01.2-1.1-1.1-1.0-1.21.01.4-1.4-1.4-1.0-1.11.1-1.10.81.0-1.01.01.2-1.2-1.2-1.20.20.40.8
Patch foraging time to switch 0 sec1.62.56.21.81.6-1.5-2.3-2.5-1.20.81.0-1.0-1.0-2.5-0.61.1-1.22.10.4-1.50.31.8-2.3-2.0-1.1-1.0-1.32.1
Patch foraging water rate 0 sec3.65.810.3-2.8-2.82.43.23.12.3-1.8-2.22.22.23.11.8-2.12.4-2.3-1.62.9-1.5-2.83.23.02.10.80.7-2.4
Patch foraging water rate 12 sec6.610.121.3-3.7-3.63.64.44.63.0-2.5-2.72.72.74.42.2-2.72.6-3.5-1.83.2-1.7-3.34.63.62.42.32.3-2.5
Patch foraging water rate 18 sec2.43.36.8-2.3-2.22.22.42.61.8-1.6-1.81.81.82.41.4-1.41.4-1.9-1.11.8-1.1-1.62.11.71.31.81.8-0.7
Patch foraging water rate 24 sec3.14.37.9-2.6-2.62.12.72.82.1-1.6-2.32.32.32.61.7-1.62.0-1.8-1.42.4-1.4-2.12.72.21.41.41.2-1.2
Patch foraging water rate 6 sec3.34.911.0-2.8-2.72.43.03.32.0-1.5-2.02.02.03.11.4-1.51.8-2.2-1.12.1-1.0-2.03.32.21.72.12.2-1.7
Seeking ratio, delayed vs. immediate footshock0.10.11.1-0.3-0.30.20.30.50.3-0.4-0.10.10.10.60.10.00.2-0.1-0.1-1.0-0.1-0.20.60.20.30.40.3-0.4
Distance traveled before self-admin0.50.51.80.91.0-0.8-1.0-1.2-0.50.50.5-0.5-0.5-1.1-0.30.3-0.40.60.2-0.40.20.4-1.2-0.5-0.3-1.3-1.30.3
Distance traveled after self-admin0.10.10.80.40.5-0.3-0.4-0.5-0.20.20.2-0.2-0.2-0.3-0.20.0-0.10.60.1-0.40.1-0.0-0.00.1-0.1-0.9-0.8-0.3
Extensor digitorum longus weight6.726.335.95.85.9-5.7-6.0-5.6-5.65.35.5-5.5-5.5-5.7-4.95.3-5.44.74.6-4.94.55.7-5.6-5.7-5.3-0.5-0.33.4
Bone: elastic displacement1.31.44.2-1.3-1.21.21.82.00.7-0.4-0.70.70.71.90.2-0.50.6-1.30.00.90.1-1.01.91.20.61.71.7-1.4
Bone: elastic work1.01.32.90.70.9-0.8-0.40.0-1.31.31.3-1.3-1.3-0.2-1.51.5-1.30.21.6-1.01.61.1-0.2-0.9-1.41.61.70.0
Bone: endosteal estimation1.02.16.3-1.2-1.31.30.1-0.31.6-1.9-1.41.41.4-0.52.3-1.61.4-0.5-2.31.8-2.4-0.4-0.20.01.4-0.6-1.12.5
Bone: endosteal perimeter1.63.38.9-1.3-1.41.50.2-0.52.0-2.2-1.71.71.7-0.62.8-2.21.9-0.7-2.92.4-3.0-0.9-0.30.52.0-1.7-2.12.4
Epididymis fat weight2.25.18.4-2.7-2.72.31.91.62.7-2.6-2.42.42.41.42.9-2.42.8-2.0-2.92.7-2.9-2.11.51.82.5-0.3-0.80.5
Delta time in closed arm before/after self-admin0.70.75.80.20.10.10.20.7-0.50.4-0.10.10.10.3-0.70.7-1.0-0.70.8-0.70.80.8-0.3-0.7-0.52.32.40.2
Delta time in open arm before/after self-admin0.40.43.50.20.3-0.6-0.3-0.6-0.10.30.6-0.6-0.6-0.40.1-0.00.40.9-0.20.3-0.2-0.40.10.4-0.0-1.9-1.8-0.6
Diff in mean of infusions in LGA sessions0.30.41.10.60.6-0.7-0.5-0.4-0.70.80.8-0.8-0.8-0.4-0.80.6-0.50.30.7-0.40.80.3-1.1-0.2-0.6-0.4-0.1-0.6
Delay discount exponential model param0.20.21.2-0.00.10.20.1-0.00.20.1-0.30.30.30.10.2-0.30.30.9-0.21.1-0.2-0.4-0.10.50.5-0.7-0.7-0.8
Extinction: sum of active levers before priming4.34.36.02.32.3-2.4-2.4-2.4-2.11.92.4-2.4-2.4-2.3-1.82.1-2.02.21.7-2.41.72.1-2.3-2.1-2.0-0.9-0.71.0
Active lever presses in extinction session 62.12.04.11.71.7-1.6-1.7-1.9-1.51.71.4-1.4-1.4-1.7-1.21.1-1.21.71.1-0.21.11.0-2.0-1.0-1.1-1.6-1.40.0
Bone: final force2.54.17.42.32.4-2.2-2.7-2.7-2.01.92.0-2.0-2.0-2.7-1.51.8-1.91.91.4-1.31.32.2-2.6-2.3-2.0-0.9-0.82.0
Bone: final moment2.23.66.62.22.2-2.1-2.5-2.6-1.91.81.9-1.9-1.9-2.6-1.41.7-1.81.91.3-1.21.22.1-2.4-2.2-1.8-0.9-0.81.9
Food consumed during 24 hour testing period0.10.20.90.20.2-0.30.0-0.1-0.10.40.1-0.1-0.10.1-0.1-0.10.20.20.10.50.1-0.50.10.50.0-1.0-0.8-1.0
Glucose1.92.85.2-2.1-1.81.91.10.92.0-2.2-2.32.32.30.82.2-1.92.0-1.2-2.21.3-2.2-1.10.70.91.80.0-0.30.9
Heart weight3.04.27.4-2.5-2.42.42.32.32.2-2.3-2.72.72.72.12.0-1.92.1-2.0-1.91.4-1.9-1.71.91.71.91.30.9-0.0
Delay discount hyperbolic model param0.20.21.1-0.10.00.30.20.00.2-0.0-0.40.40.40.20.2-0.40.30.8-0.21.1-0.2-0.5-0.10.50.5-0.7-0.7-1.0
Intermittent access intake day 1-15 change1.01.02.5-0.9-0.90.70.90.61.0-0.6-0.70.70.70.71.0-1.01.2-1.2-1.01.6-0.9-1.40.21.40.9-1.3-1.3-1.1
Intermittent access intake escalation0.90.91.9-0.8-0.80.70.80.50.9-0.7-0.70.70.70.61.0-1.01.1-1.0-1.01.4-1.0-1.30.31.20.9-1.2-1.2-0.9
Intermittent access intake escalation 20.50.51.9-0.4-0.40.40.50.20.5-0.2-0.40.40.40.50.5-0.70.8-0.6-0.60.9-0.5-1.10.11.10.6-1.4-1.4-1.1
Intermitt. access day 1 inactive lever presses2.42.66.0-1.7-1.71.81.61.41.9-1.9-1.61.61.61.51.7-1.81.8-2.5-1.71.2-1.7-1.80.81.71.7-0.4-0.7-0.6
Intermitt. access day 15 inactive lever presses3.43.85.3-1.9-1.82.11.61.22.2-2.1-2.12.12.11.32.2-2.32.2-2.3-2.31.9-2.3-2.20.62.12.2-1.5-1.5-0.8
Intermitt. access escalation Index2.32.16.3-1.8-1.81.51.61.81.5-1.7-1.61.61.61.61.3-1.11.4-0.4-1.10.9-1.2-0.92.51.01.11.51.2-0.4
Intermittent access day 1 total infusions5.36.111.5-2.7-2.62.81.71.33.0-3.4-3.03.03.01.23.4-3.02.8-2.6-3.32.5-3.4-1.90.81.62.6-0.4-0.61.1
Intermittent access day 15 total infusions8.79.715.0-3.3-3.33.32.61.93.7-3.6-3.53.53.52.03.9-3.73.6-3.4-3.93.8-3.9-3.21.22.93.3-1.4-1.5-0.2
Intermittent access terminal intake (last 3 days)6.36.912.9-2.7-2.72.61.81.13.1-3.0-2.92.92.91.13.5-3.13.1-2.6-3.63.5-3.6-2.50.62.22.7-1.8-1.90.6
Intermittent access total infusions5.46.011.2-2.5-2.52.61.61.02.9-3.1-2.92.92.91.03.3-2.92.8-2.3-3.32.8-3.4-2.10.51.82.7-1.3-1.40.6
Intermittent access day 1 locomotion3.43.67.1-2.2-2.12.21.31.22.3-2.7-2.32.32.30.92.5-2.12.0-2.6-2.41.5-2.5-1.10.40.81.80.70.51.4
Intermittent access day 15 total locomotion5.35.710.3-2.5-2.52.41.91.42.8-2.8-2.72.72.71.52.9-2.82.8-3.2-3.02.5-2.9-2.40.42.22.4-1.3-1.2-0.1
Intermittent access total locomotion6.57.414.5-2.9-2.92.81.81.13.3-3.5-3.23.23.21.13.7-3.23.2-2.9-3.82.9-3.8-2.30.51.92.9-1.4-1.50.9
Intermittent access standard deviation1.51.63.3-1.2-1.21.21.20.91.4-1.1-1.31.31.31.01.4-1.41.4-1.8-1.41.5-1.3-1.60.21.51.4-1.0-1.0-0.8
Left kidney weight0.71.83.6-1.4-1.41.21.10.81.5-1.4-1.91.91.90.81.6-1.41.6-0.5-1.61.7-1.6-1.41.01.31.4-0.6-1.0-0.1
Right kidney weight0.41.03.6-0.6-0.60.50.4-0.10.9-0.7-1.01.01.00.11.2-1.11.2-0.4-1.31.7-1.3-1.2-0.21.01.0-1.6-1.90.1
Cocaine induced anxiety0.10.21.00.10.1-0.1-0.3-0.50.00.00.2-0.2-0.2-0.40.2-0.10.10.1-0.30.7-0.3-0.1-0.70.0-0.1-1.0-1.00.3
Post-drug Anxiety1.11.23.91.21.2-1.0-1.3-1.6-1.01.11.1-1.1-1.1-1.4-0.70.7-0.90.60.50.00.50.7-2.0-0.8-0.8-1.5-1.80.5
Baseline Anxiety1.92.03.41.61.6-1.5-1.4-1.2-1.71.71.5-1.5-1.5-1.2-1.61.5-1.70.41.6-1.51.61.5-1.8-1.4-1.50.30.10.5
Tail length0.92.75.81.51.6-1.8-0.9-0.5-2.12.42.2-2.2-2.2-0.7-2.32.1-1.80.62.3-0.92.31.2-0.8-1.0-1.81.01.0-0.6
Length with tail1.76.110.13.03.0-2.8-2.4-2.2-3.03.22.7-2.7-2.7-2.3-2.92.7-2.92.12.8-1.72.82.4-2.4-2.3-2.70.10.20.8
Length without tail1.32.95.22.32.3-1.8-2.1-2.0-1.91.91.2-1.2-1.2-1.9-1.71.5-2.01.71.5-1.31.51.8-2.2-1.8-1.7-0.6-0.21.2
Times rat made contact with spout0.70.82.60.70.7-0.8-0.4-0.2-0.90.81.3-1.3-1.3-0.1-1.11.0-1.00.31.2-1.61.20.7-0.3-0.6-1.10.60.8-0.4
Lifetime Intake4.45.09.3-2.4-2.32.51.51.12.7-2.9-2.72.72.71.03.0-2.72.5-2.3-3.02.4-3.0-1.80.41.52.4-0.7-0.90.8
Liver weight, left0.10.11.0-0.2-0.20.2-0.0-0.10.2-0.2-0.00.00.0-0.30.4-0.20.2-0.3-0.40.5-0.50.0-0.1-0.20.40.1-0.11.0
Liver weight, right0.20.33.2-0.2-0.30.2-0.00.1-0.0-0.00.5-0.5-0.5-0.30.10.2-0.3-0.5-0.10.9-0.10.50.1-0.6-0.31.20.81.8
Locomotor activity1.62.56.4-1.9-1.91.72.32.51.4-1.1-1.31.31.32.30.9-1.01.2-2.1-0.71.2-0.6-1.52.01.60.91.91.9-1.1
Locomotor testing distance2.23.69.7-2.2-2.32.12.73.11.5-1.2-1.41.41.42.80.9-1.11.3-2.7-0.61.4-0.6-1.62.51.70.92.72.7-1.1
Locomotor testing rearing1.72.67.7-1.8-1.91.92.32.61.4-1.2-1.31.31.32.30.9-1.01.1-2.8-0.70.9-0.7-1.42.01.51.02.12.0-0.6
Locomotion in novel chamber5.06.111.5-2.6-2.52.52.11.62.9-2.6-2.62.62.61.73.0-3.03.0-1.9-3.13.4-3.0-2.71.22.52.8-1.4-1.7-0.7
Locomotion in novel chamber post-restriction2.93.55.0-2.1-2.12.01.91.62.1-2.1-2.12.12.11.62.1-2.02.0-1.7-2.02.2-2.0-2.01.91.92.1-0.3-0.5-0.8
Fecal boli incidents, locomotor time 10.50.64.80.30.3-0.4-0.7-1.10.10.00.0-0.0-0.0-1.00.5-0.20.50.6-0.60.8-0.6-0.2-0.80.00.3-1.8-2.20.3
Change in fecal boli incidents, locomotor task0.60.54.0-0.2-0.10.20.10.5-0.20.10.2-0.2-0.20.2-0.30.5-0.6-0.90.5-0.70.40.8-0.4-0.7-0.52.02.00.8
Time >=10cm from walls, locomotor time 11.41.44.3-0.7-0.70.6-0.2-0.71.3-1.3-1.01.01.0-0.71.9-1.21.4-0.1-2.01.6-2.1-0.4-1.10.11.3-1.5-1.61.3
Bouts of movement, locomotor time 11.21.35.61.11.3-1.2-0.6-0.5-1.11.11.0-1.0-1.0-0.0-1.50.7-0.81.11.4-2.41.50.20.1-0.0-0.8-0.9-0.7-2.1
Total resting periods, locomotor time 10.80.83.60.91.0-1.0-0.6-0.5-0.80.80.7-0.7-0.7-0.1-1.10.5-0.51.21.1-1.91.10.10.10.1-0.5-1.1-0.9-1.9
Rest time, locomotor task time 11.21.32.1-1.4-1.31.21.41.31.3-1.0-0.90.90.91.31.1-1.11.3-0.9-1.01.4-1.0-1.31.21.51.3-0.0-0.1-1.5
Distance moved, locomotor task time 10.30.31.90.40.3-0.4-0.6-0.6-0.30.10.6-0.6-0.6-0.8-0.10.4-0.40.40.1-0.30.00.7-0.9-0.8-0.60.10.01.4
Vertical activity count, locomotor time 11.11.12.9-1.2-1.31.21.21.11.2-1.2-0.90.90.91.01.2-1.11.1-1.7-1.11.0-1.1-1.10.70.91.10.30.30.3
Time >=10cm from walls, locomotor time 20.20.32.10.40.4-0.2-0.4-0.60.1-0.10.4-0.4-0.4-0.30.2-0.40.30.2-0.30.0-0.3-0.2-0.50.20.3-1.4-1.2-0.4
Bouts of movement, locomotor time 20.40.42.90.60.7-0.7-0.4-0.3-0.70.50.5-0.5-0.5-0.1-0.90.5-0.5-0.00.9-1.70.90.3-0.1-0.2-0.5-0.2-0.1-0.6
Total resting periods, locomotor time 20.20.22.20.30.4-0.5-0.2-0.2-0.40.20.2-0.2-0.2-0.0-0.60.3-0.2-0.20.5-1.50.50.10.1-0.1-0.3-0.2-0.1-0.4
Rest time, locomotor task time 22.12.43.5-1.8-1.81.71.61.41.9-1.7-1.91.91.91.31.8-1.61.7-1.7-1.81.3-1.8-1.41.01.41.80.30.1-0.2
Distance moved, locomotor task time 21.01.22.31.31.2-1.2-1.0-0.9-1.21.21.5-1.5-1.5-0.8-1.21.1-1.21.21.2-0.81.20.9-1.0-0.8-1.2-0.3-0.1-0.1
Vertical activity count, locomotor time 20.30.31.6-0.0-0.20.10.70.9-0.20.60.3-0.3-0.30.8-0.50.4-0.3-0.20.70.30.7-0.20.50.4-0.31.01.3-0.8
Light reinforcement 10.10.31.2-0.3-0.40.40.80.80.3-0.20.1-0.1-0.10.90.1-0.30.2-0.7-0.00.3-0.0-0.70.40.80.40.30.4-1.1
Light reinforcement 21.82.55.4-0.9-1.01.60.80.31.6-1.5-1.91.91.90.51.8-2.11.5-0.7-1.92.3-1.9-1.70.41.52.2-1.9-1.9-0.7
Bone: marrow area1.02.16.3-1.3-1.41.40.2-0.21.7-1.9-1.41.41.4-0.42.3-1.61.4-0.6-2.31.7-2.4-0.4-0.20.01.4-0.5-1.02.5
Bone: maximum diameter0.40.83.90.60.6-0.6-1.1-1.5-0.10.30.3-0.3-0.3-1.50.4-0.20.20.8-0.61.3-0.60.2-0.9-0.40.0-1.9-2.01.3
Bone: maximum force3.05.112.12.42.5-2.3-3.2-3.5-1.91.71.9-1.9-1.9-3.5-1.11.7-1.82.20.9-1.40.82.5-3.5-2.8-1.8-1.6-1.63.0
Bone: maximum moment2.64.410.52.22.3-2.2-3.0-3.2-1.81.51.7-1.7-1.7-3.2-1.01.6-1.62.10.8-1.30.72.4-3.1-2.6-1.6-1.4-1.42.8
Mean time between licks in bursts0.91.33.90.50.7-0.6-0.40.1-1.21.11.0-1.0-1.0-0.1-1.51.4-1.30.31.6-1.21.61.2-0.1-1.0-1.51.92.00.1
Mean num. licks in bursts0.20.20.7-0.5-0.40.40.60.80.2-0.2-0.10.10.10.8-0.1-0.00.1-0.60.2-0.40.2-0.20.50.30.10.80.9-0.6
Cd content in liver1.21.44.2-1.1-1.20.91.10.71.2-0.9-0.60.60.60.81.3-1.31.5-1.1-1.32.1-1.3-1.60.91.51.1-1.2-1.2-0.5
Co content in liver1.71.96.4-1.3-1.31.22.22.50.7-0.5-0.30.30.32.5-0.0-0.50.5-1.70.30.30.3-1.42.31.70.61.81.9-2.2
Cu content in liver0.20.31.30.70.6-0.7-0.5-0.4-0.50.40.6-0.6-0.6-0.3-0.60.6-0.50.70.6-1.10.60.4-0.2-0.4-0.4-0.2-0.1-0.3
Fe content in liver0.20.30.80.50.4-0.6-0.7-0.9-0.40.50.5-0.5-0.5-0.9-0.10.3-0.10.4-0.00.5-0.00.4-0.9-0.4-0.0-0.9-0.40.7
K content in liver1.91.83.91.31.2-1.3-1.8-1.7-1.20.91.4-1.4-1.4-1.9-0.81.4-1.21.20.7-1.30.61.9-1.6-2.0-1.00.1-0.12.0
Mg content in liver0.30.31.70.20.2-0.1-0.7-0.7-0.1-0.40.3-0.3-0.3-0.80.20.1-0.10.3-0.2-1.2-0.30.8-0.7-0.90.10.0-0.11.3
Mn content in liver1.82.14.31.81.8-1.7-1.9-2.1-1.41.51.5-1.5-1.5-1.9-1.11.2-1.01.50.9-0.70.91.2-1.9-1.3-0.8-1.6-1.30.4
Na content in liver0.91.01.71.31.3-1.1-1.2-1.3-1.01.11.1-1.1-1.1-1.3-0.70.8-1.01.10.6-0.10.60.9-1.2-0.9-0.6-0.7-0.80.6
Rb content in liver1.21.53.2-1.6-1.51.61.21.21.4-1.7-1.31.31.31.11.3-1.31.4-1.8-1.30.5-1.3-1.00.70.91.40.60.40.3
Se content in liver0.60.75.50.0-0.0-0.2-0.4-0.90.5-0.3-0.50.50.5-0.60.8-0.61.00.7-1.00.9-1.0-0.5-0.40.40.8-2.4-2.0-0.2
Sr content in liver2.52.34.12.01.9-2.0-1.5-1.4-1.92.01.6-1.6-1.6-1.3-1.81.7-1.71.41.7-1.11.81.1-0.9-1.0-1.5-0.9-0.6-0.5
Zn content in liver0.91.02.31.51.2-1.2-1.2-1.2-1.11.00.9-0.9-0.9-1.0-1.01.0-1.11.30.9-1.50.91.0-0.9-0.9-0.8-0.6-0.20.3
Bone: minimum diameter0.81.54.3-1.1-1.11.20.1-0.21.5-1.9-1.21.21.2-0.31.9-1.51.3-0.5-2.00.8-2.1-0.40.10.11.4-0.6-1.02.0
Time in familiar zone, hab. session 10.20.20.5-0.5-0.50.50.30.20.6-0.7-0.30.30.30.20.7-0.50.4-0.2-0.60.4-0.6-0.20.00.20.30.1-0.10.0
Time in novel zone, hab. session 10.30.31.4-0.5-0.40.40.70.90.10.1-0.30.30.30.8-0.20.10.0-1.10.30.10.3-0.30.60.30.11.11.20.1
Total zone transitions, hab. session 10.60.92.11.21.0-0.8-0.9-0.9-0.80.71.5-1.5-1.5-0.8-0.80.7-1.10.30.7-1.20.70.8-1.1-0.8-0.7-0.2-0.10.6
Total locomotion distance, hab. session 10.20.30.9-0.4-0.60.70.20.10.8-0.9-0.00.00.00.10.9-0.70.4-0.9-0.90.4-1.0-0.2-0.30.10.80.0-0.10.8
Locomotion velocity, hab. session 10.10.10.40.1-0.10.2-0.1-0.20.3-0.40.5-0.5-0.5-0.20.4-0.2-0.0-0.2-0.4-0.0-0.40.1-0.4-0.20.3-0.1-0.10.6
Time in familiar zone, hab. session 20.40.42.6-0.1-0.20.00.30.6-0.40.40.4-0.4-0.40.4-0.60.6-0.60.10.80.10.80.50.9-0.3-0.81.61.6-0.4
Time in novel zone, hab. session 20.20.20.70.20.3-0.2-0.4-0.50.0-0.1-0.10.10.1-0.30.1-0.10.1-0.0-0.2-0.7-0.2-0.0-0.8-0.10.2-0.8-0.80.6
Total zone transitions, hab. session 21.51.94.11.61.4-1.1-1.7-1.6-1.20.71.4-1.4-1.4-1.6-0.91.2-1.61.00.8-2.00.71.8-1.8-1.9-1.20.20.22.0
Total locomotion distance, hab. session 20.20.32.40.2-0.00.1-0.5-0.40.1-0.40.5-0.5-0.5-0.50.30.2-0.4-0.1-0.3-0.7-0.40.8-0.6-0.9-0.10.60.41.5
Locomotion velocity, hab. session 20.20.32.2-0.1-0.30.3-0.4-0.40.4-0.70.2-0.2-0.2-0.50.7-0.2-0.0-0.1-0.7-0.3-0.80.5-0.6-0.70.20.20.01.5
Novel to familiar place preference ratio1.01.13.81.21.2-1.3-1.4-1.7-0.80.80.2-0.2-0.2-1.5-0.40.5-0.41.40.2-0.70.20.5-1.4-0.7-0.6-2.0-1.80.6
Novelty place preference0.60.63.00.80.8-1.0-1.0-1.3-0.40.4-0.20.20.2-1.1-0.10.2-0.11.0-0.0-0.5-0.00.2-1.0-0.3-0.3-1.7-1.60.3
Time in novel zone, NPP test0.40.42.10.70.6-0.9-0.9-1.1-0.40.4-0.20.20.2-1.0-0.10.2-0.10.90.0-0.5-0.00.2-0.8-0.3-0.3-1.4-1.40.4
Total zone transitions, NPP test2.23.15.62.22.0-1.7-2.1-2.1-1.71.51.9-1.9-1.9-2.1-1.41.6-2.01.31.3-1.91.32.0-2.4-2.0-1.6-0.3-0.21.7
Total locomotion distance, NPP test0.20.31.70.40.30.0-0.5-0.5-0.1-0.20.5-0.5-0.5-0.50.00.2-0.5-0.2-0.1-0.8-0.10.7-0.8-0.8-0.10.40.31.3
Locomotion velocity, NPP test0.10.20.80.40.3-0.1-0.5-0.5-0.1-0.10.5-0.5-0.5-0.5-0.00.2-0.5-0.1-0.0-0.9-0.10.6-0.9-0.7-0.10.10.10.9
Intraocular pressure1.52.04.9-1.4-1.20.81.30.91.3-0.7-1.51.51.51.21.3-1.31.9-0.6-1.31.8-1.2-1.90.32.01.3-1.7-1.7-2.2
Delta distance traveled before/after self-admin0.20.20.9-0.3-0.30.30.50.70.1-0.1-0.00.00.00.6-0.10.00.0-0.10.2-0.00.2-0.11.00.2-0.20.90.9-0.1
Delta ambulatory time before/after self-admin0.20.21.5-0.2-0.20.10.40.7-0.10.10.2-0.2-0.20.5-0.40.2-0.2-0.20.4-0.30.40.10.80.0-0.31.21.20.1
Parametrial fat weight1.63.26.7-2.1-2.22.01.20.92.2-2.6-1.91.91.90.72.5-2.12.0-1.3-2.51.7-2.6-1.20.91.01.7-0.1-0.91.4
Pavlov. Cond. lever latency0.30.41.0-0.6-0.60.80.91.00.5-0.5-0.60.60.61.00.3-0.60.5-0.9-0.20.6-0.2-0.80.80.90.70.30.3-0.6
Pavlov. Cond. magazine entry latency0.30.41.30.60.5-0.7-0.9-1.0-0.40.20.7-0.7-0.7-0.9-0.20.4-0.30.60.1-1.10.00.6-0.8-0.8-0.4-0.6-0.60.8
Pavlov. Cond. change in total contacts0.30.32.10.40.2-0.3-0.5-0.80.2-0.2-0.40.40.4-0.60.4-0.30.20.8-0.5-0.4-0.5-0.1-0.60.00.3-1.5-1.50.0
Pavlov. Cond. index score0.20.20.50.50.5-0.7-0.6-0.7-0.40.40.5-0.5-0.5-0.6-0.20.4-0.20.70.2-0.50.20.3-0.5-0.4-0.4-0.7-0.7-0.1
Pavlov. Cond. latency score0.10.20.40.40.3-0.5-0.6-0.6-0.30.20.5-0.5-0.5-0.6-0.10.4-0.20.60.1-0.50.10.4-0.4-0.4-0.4-0.4-0.40.1
Pavlov. Cond. lever contacts0.10.10.20.20.1-0.3-0.3-0.3-0.20.20.3-0.3-0.3-0.4-0.10.4-0.20.30.1-0.40.00.4-0.3-0.4-0.40.10.10.4
Pavlov. Cond. magazine entry number0.30.31.5-0.7-0.60.80.60.80.4-0.5-0.50.50.50.60.3-0.30.2-0.7-0.20.4-0.3-0.10.40.10.31.21.10.5
Pavlov. Cond. intertrial magazine entries0.91.03.0-0.8-0.90.91.11.01.0-0.8-1.11.11.11.20.8-1.11.0-0.3-0.70.9-0.7-1.31.31.41.1-0.5-0.5-1.7
Pavlov. Cond. lever-magazine prob. diff.0.40.51.00.80.7-0.9-0.9-1.0-0.60.60.8-0.8-0.8-0.9-0.40.6-0.51.00.4-0.80.30.6-0.7-0.6-0.6-0.8-0.70.1
Pavlov. Cond. response bias0.10.10.60.40.4-0.6-0.4-0.5-0.20.30.4-0.4-0.4-0.4-0.20.2-0.10.50.1-0.40.10.1-0.4-0.1-0.2-0.8-0.7-0.3
Pavlov. Cond. lever latency0.50.62.0-0.7-0.80.81.21.40.5-0.6-0.40.40.41.40.1-0.30.1-0.80.0-0.10.0-0.61.30.70.51.21.2-0.9
Pavlov. Cond. magazine entry latency3.13.55.12.22.2-2.2-2.3-2.2-2.01.81.9-1.9-1.9-2.1-1.81.8-1.82.01.7-2.21.61.9-2.0-1.9-2.1-0.8-0.60.9
Pavlov. Cond. change in total contacts1.41.96.31.61.6-1.6-1.9-2.3-1.00.90.8-0.8-0.8-2.0-0.50.5-0.51.70.3-1.00.30.8-2.1-1.0-0.5-2.5-2.40.6
Pavlov. Cond. index score1.92.45.61.81.9-1.9-2.2-2.4-1.41.41.1-1.1-1.1-2.2-1.01.1-1.12.00.8-1.20.81.4-2.1-1.5-1.3-1.7-1.61.0
Pavlov. Cond. latency score1.62.05.01.61.7-1.6-2.0-2.2-1.21.21.0-1.0-1.0-2.1-0.80.9-0.91.80.6-0.90.51.3-2.0-1.4-1.2-1.6-1.51.2
Pavlov. Cond. lever contacts0.40.51.60.80.9-0.8-0.9-1.2-0.60.70.3-0.3-0.3-1.1-0.30.3-0.20.90.20.30.20.4-1.1-0.4-0.5-1.3-1.20.2
Pavlov. Cond. magazine entry number4.96.09.5-3.0-3.03.03.03.12.6-2.4-2.42.42.42.92.3-2.22.3-2.6-2.02.6-2.0-2.32.82.42.41.61.3-1.1
Pavlov. Cond. intertrial magazine entries0.81.01.9-1.4-1.31.01.11.01.2-1.0-0.70.70.71.01.2-0.91.2-0.9-1.11.4-1.1-1.00.91.01.00.1-0.0-0.6
Pavlov. Cond. lever-magazine prob. diff.2.32.96.22.02.1-2.1-2.3-2.5-1.71.61.4-1.4-1.4-2.3-1.31.3-1.32.11.0-1.41.01.6-2.2-1.7-1.6-1.6-1.51.0
Pavlov. Cond. response bias1.31.83.91.61.7-1.7-1.8-2.0-1.31.41.0-1.0-1.0-1.8-1.01.0-0.91.60.8-0.80.81.1-1.7-1.2-1.2-1.5-1.40.6
Time in closed arm before self-admin0.30.31.90.20.2-0.2-0.5-0.80.1-0.10.2-0.2-0.2-0.70.3-0.20.30.9-0.40.4-0.4-0.0-0.6-0.1-0.0-1.3-1.40.6
Time in closed arm after self-admin0.20.21.1-0.2-0.30.50.30.40.2-0.4-0.40.40.40.30.2-0.2-0.1-0.3-0.1-0.1-0.10.2-0.4-0.20.21.01.00.4
Time in open arm before self-admin1.11.27.7-0.8-0.80.71.21.70.2-0.3-0.30.30.31.5-0.30.2-0.1-1.60.5-0.70.5-0.11.10.2-0.02.82.8-0.5
Time in open arm after self-admin0.30.31.8-0.4-0.30.10.80.90.10.10.0-0.0-0.00.9-0.20.00.3-0.20.30.10.3-0.61.30.70.00.30.4-1.3
Bone: periosteal estimation0.40.94.4-0.1-0.10.1-0.8-1.20.5-0.6-0.30.30.3-1.31.2-0.70.60.3-1.31.3-1.40.2-0.9-0.50.5-1.3-1.62.1
Bone: periosteal perimeter0.40.62.60.40.3-0.3-0.9-1.30.1-0.10.1-0.1-0.1-1.30.6-0.30.10.5-0.80.7-0.80.3-1.0-0.60.1-1.3-1.51.6
Bone: post-yield work2.02.710.20.60.6-0.3-2.1-2.70.4-1.1-0.30.30.3-2.61.4-0.70.41.4-1.7-0.5-1.81.0-2.5-1.50.5-2.5-2.93.2
Progressive ratio test 1 active lever presses3.33.44.9-2.0-1.92.01.81.52.1-2.1-2.12.12.11.62.1-2.22.1-1.7-2.11.9-2.0-2.01.31.92.0-0.5-0.4-0.7
Progressive ratio test 1 breakpoint2.83.04.0-1.9-1.81.81.71.52.0-1.9-1.91.91.91.51.9-2.02.0-1.5-1.92.0-1.9-1.91.41.91.8-0.5-0.4-0.7
Progressive ratio test 1 inactive lever presses1.11.31.9-1.3-1.21.31.31.31.3-1.3-1.41.41.41.31.1-1.21.1-1.3-1.00.6-1.0-1.10.91.10.80.40.3-0.2
Progressive ratio test 2 active lever presses5.25.68.5-2.5-2.42.52.01.42.8-2.7-2.62.62.61.62.9-2.92.8-2.4-2.92.8-2.9-2.51.02.32.7-1.4-1.6-0.6
Progressive ratio test 2 breakpoint6.37.19.8-2.8-2.82.82.52.13.0-2.9-2.92.92.92.23.0-3.13.1-2.7-3.03.1-2.9-3.01.72.93.0-1.1-1.2-1.3
Progressive ratio test 2 inactive lever presses9.010.314.7-3.4-3.43.32.92.33.8-3.7-3.53.53.52.53.8-3.73.8-3.4-3.83.4-3.8-3.51.43.33.3-1.5-1.8-0.9
Incentive Sensitization - Responses0.90.91.6-0.9-0.80.80.50.21.0-1.1-0.90.90.90.31.2-1.21.2-1.0-1.31.2-1.3-1.0-0.00.81.1-1.1-1.3-0.2
Incentive Sensitization - Breakpoint1.21.22.1-1.1-1.01.00.70.41.2-1.3-1.01.01.00.51.4-1.41.4-1.3-1.41.4-1.4-1.20.11.11.3-1.2-1.3-0.3
Sum of active levers in priming session hrs 5-61.31.27.01.21.3-1.1-1.1-1.5-0.81.20.6-0.6-0.6-1.1-0.50.2-0.31.40.40.50.4-0.0-1.60.1-0.3-2.6-2.3-1.1
Progressive ratio2.52.96.61.81.8-1.8-2.4-2.4-1.41.11.8-1.8-1.8-2.4-0.91.5-1.51.30.7-1.90.62.1-2.6-2.2-1.3-0.8-0.72.1
Food seeking constrained by brief footshock0.30.41.80.20.2-0.5-0.10.2-0.70.60.4-0.4-0.4-0.0-0.80.8-0.7-0.20.9-0.80.90.7-0.4-0.6-0.81.21.30.3
Seeking ratio, punishment vs. effort2.12.56.9-1.7-1.81.62.32.61.1-0.9-1.61.61.62.50.4-0.91.0-1.4-0.21.1-0.2-1.52.61.70.81.91.9-1.7
Retroperitoneal fat weight4.815.722.2-4.6-4.54.53.83.34.7-4.7-4.74.74.73.14.7-4.44.5-2.7-4.64.3-4.6-3.73.63.54.20.0-0.6-0.2
Reaction time number correct0.30.41.10.50.7-0.7-0.4-0.4-0.71.10.7-0.7-0.7-0.4-0.80.8-0.60.60.80.00.80.5-0.5-0.4-0.70.20.3-0.3
Reaction time mean minus median2.53.37.42.12.3-2.1-2.5-2.7-1.71.61.7-1.7-1.7-2.5-1.31.3-1.21.51.0-1.41.01.5-2.6-1.7-1.5-1.9-1.91.1
Reaction time mean minus median AUC1.31.73.21.51.7-1.6-1.6-1.8-1.31.41.5-1.5-1.5-1.6-1.11.1-0.81.00.9-0.90.91.0-1.7-1.1-1.3-1.2-1.20.4
Reaction time num false alarms0.60.84.9-0.8-0.40.81.11.50.2-0.4-0.70.70.71.3-0.20.0-0.0-0.70.4-0.30.4-0.11.00.30.12.22.2-0.8
Reaction time num false alarms AUC0.50.64.6-0.10.20.10.40.9-0.40.3-0.00.00.00.7-0.80.7-0.7-0.11.0-0.91.00.50.3-0.3-0.62.12.1-0.5
Reaction time trials correct on left0.30.41.10.50.7-0.7-0.4-0.4-0.71.10.7-0.7-0.7-0.4-0.80.8-0.60.60.80.00.80.5-0.5-0.4-0.70.20.3-0.3
Reaction time trials on left0.30.51.30.60.8-0.8-0.5-0.4-0.81.20.8-0.8-0.8-0.4-0.80.8-0.70.60.8-0.00.90.6-0.6-0.5-0.80.20.3-0.3
Reaction time mean0.20.21.80.20.3-0.1-0.3-0.60.1-0.2-0.10.10.1-0.30.2-0.40.3-0.4-0.3-0.2-0.3-0.4-0.50.20.1-1.3-1.30.1
Reaction time mean AUC0.20.32.00.20.2-0.1-0.3-0.60.2-0.3-0.10.10.1-0.30.3-0.50.4-0.4-0.5-0.3-0.5-0.4-0.60.30.1-1.4-1.40.1
Median of all reaction times0.20.31.2-0.3-0.20.40.2-0.10.5-0.6-0.50.50.50.10.6-0.80.6-0.8-0.7-0.0-0.7-0.70.00.60.4-1.1-1.10.1
Reaction time omissions0.70.92.61.11.5-0.8-1.1-1.0-1.10.90.7-0.7-0.7-0.8-1.10.6-0.80.21.0-1.61.00.8-1.5-0.8-1.1-0.5-0.40.1
Reaction time false alarm rate0.40.53.4-0.6-0.50.70.81.10.2-0.5-0.60.60.61.0-0.10.0-0.1-0.50.2-0.40.20.00.80.10.11.81.8-0.3
Reaction time premature initiation rate3.04.06.91.92.0-1.7-1.4-0.9-2.42.22.3-2.3-2.3-1.1-2.62.4-2.51.32.6-2.12.62.2-0.5-2.0-2.41.81.90.7
Reaction time premature initiations4.25.910.32.42.6-2.3-1.8-1.2-2.93.02.8-2.8-2.8-1.3-3.22.9-2.91.83.2-2.33.22.4-1.0-2.2-2.91.61.90.3
Std. dev. reaction times0.60.82.31.11.2-1.0-1.2-1.4-0.70.60.7-0.7-0.7-1.1-0.50.3-0.40.60.4-0.80.40.4-1.4-0.5-0.6-1.5-1.50.0
Reaction time trials completed0.30.51.30.60.8-0.8-0.5-0.4-0.81.20.8-0.8-0.8-0.4-0.80.8-0.70.60.8-0.00.90.6-0.6-0.5-0.80.20.3-0.3
Reaction time trials AUC0.20.30.90.40.6-0.6-0.3-0.2-0.61.00.6-0.6-0.6-0.3-0.70.7-0.60.50.70.10.70.5-0.4-0.4-0.60.40.4-0.2
Run reversals in cocaine runway, females1.11.14.00.60.6-0.4-0.8-0.4-0.80.10.6-0.6-0.6-0.8-0.70.9-1.10.30.8-1.50.71.7-0.8-1.7-1.02.01.91.7
Run reversals in cocaine runway, males0.30.31.5-0.6-0.60.10.80.70.30.30.5-0.5-0.50.60.20.10.4-0.9-0.11.2-0.1-0.60.60.60.00.30.3-0.1
Latency to leave start box in cocaine runway0.10.10.4-0.1-0.20.4-0.2-0.30.4-0.6-0.10.10.1-0.40.6-0.30.20.0-0.60.0-0.60.10.0-0.30.6-0.2-0.40.6
Latency to leave start box in cocaine runway, F0.10.10.30.20.0-0.0-0.3-0.30.0-0.20.1-0.1-0.1-0.20.10.1-0.00.2-0.1-0.5-0.20.10.5-0.10.3-0.5-0.5-0.1
Latency to leave start box in cocaine runway, M0.20.20.9-0.3-0.20.5-0.1-0.20.3-0.5-0.20.20.2-0.30.5-0.40.2-0.1-0.50.7-0.60.2-0.7-0.30.40.10.01.0
Std. dev. time between licks in bursts0.40.53.9-0.5-0.30.50.71.1-0.20.1-0.10.10.10.8-0.50.3-0.3-0.60.7-0.30.70.20.9-0.1-0.42.02.0-0.2
Total sessions with >9 infusions1.82.03.8-1.6-1.61.81.11.01.7-1.9-1.61.61.60.81.8-1.61.4-2.0-1.81.4-1.8-0.80.60.61.40.70.41.0
Short access day 1 total inactive lever presses4.24.77.6-2.5-2.42.62.22.12.5-2.6-2.62.62.62.12.3-2.42.3-2.7-2.21.4-2.2-2.01.32.02.30.50.3-0.6
Short access day 10 total inactive lever presses3.33.66.7-2.2-2.22.22.42.61.9-2.0-2.02.02.02.51.5-1.71.7-2.6-1.31.0-1.3-1.81.91.81.71.61.4-1.1
Short access day 1 total infusions2.83.06.5-2.0-1.82.11.31.12.1-2.6-2.22.22.21.12.2-2.11.9-1.5-2.21.4-2.2-1.21.21.01.80.3-0.10.6
Short access day 10 total infusions1.92.25.1-1.4-1.41.60.50.21.8-2.3-1.91.91.90.12.2-1.71.5-1.3-2.21.1-2.3-0.5-0.30.21.6-0.2-0.51.6
Short access total infusions1.51.73.8-1.4-1.31.60.70.61.6-2.0-1.71.71.70.41.8-1.51.3-1.4-1.81.1-1.8-0.6-0.00.41.30.30.01.3
Short access day 1 locomotion2.22.34.9-1.7-1.71.81.11.01.8-2.2-1.91.91.90.81.9-1.71.5-2.1-1.91.3-1.9-0.90.60.71.30.60.21.0
Short access day 10 total locomotion1.41.63.5-1.5-1.51.40.90.81.6-1.9-1.61.61.60.71.7-1.41.4-1.2-1.60.8-1.7-0.80.80.61.30.30.40.5
Short access total locomotion1.41.43.3-1.3-1.31.40.80.81.4-1.8-1.61.61.60.61.5-1.31.1-1.7-1.50.6-1.5-0.60.30.41.10.60.50.9
One hour access (0.3 mA shock)10.111.817.0-3.7-3.83.83.32.84.0-3.7-3.93.93.92.84.0-3.93.9-3.4-3.94.1-3.8-3.72.33.53.6-0.9-1.0-1.0
Compulsive drug intake3.63.77.61.81.7-1.7-0.9-0.3-2.22.21.9-1.9-1.9-0.4-2.62.2-2.32.32.7-2.32.81.70.3-1.4-2.11.92.1-0.5
One hour access (shock baseline)10.612.318.8-3.6-3.53.62.82.04.1-3.9-3.93.93.92.24.3-4.24.1-3.6-4.34.2-4.3-3.81.43.53.7-2.4-2.6-0.7
Social response proportion0.80.91.51.21.1-1.2-1.2-1.2-0.90.91.0-1.0-1.0-1.2-0.70.8-0.80.70.6-0.70.60.8-0.9-0.9-0.8-1.0-0.70.4
Social responses0.40.61.50.50.7-1.1-0.5-0.4-0.81.11.2-1.2-1.2-0.4-0.81.1-0.60.60.8-0.30.80.5-0.4-0.4-0.8-0.10.1-0.2
Social time0.40.61.20.60.9-0.9-0.5-0.4-0.91.11.0-1.0-1.0-0.4-0.91.0-0.70.30.9-0.40.90.7-0.7-0.6-1.00.30.40.2
Soleus weight3.29.513.7-3.7-3.73.73.43.33.6-3.5-3.13.13.13.23.3-3.33.3-2.7-3.13.2-3.1-3.13.03.03.30.90.2-1.2
Bone: stiffness2.43.89.72.22.2-2.0-2.8-3.0-1.61.31.6-1.6-1.6-2.9-0.91.3-1.52.10.7-1.40.62.0-3.1-2.2-1.4-1.8-1.82.1
Tibialis anterior weight9.131.043.26.66.6-6.6-6.3-6.0-6.36.46.3-6.3-6.3-6.0-5.65.9-5.95.55.3-3.95.25.7-5.6-5.6-5.8-1.2-0.92.6
Time to tail flick, vehicle, before self-admin0.80.83.40.90.9-0.9-1.3-1.4-0.70.60.7-0.7-0.7-1.5-0.30.7-0.70.40.1-0.40.11.0-1.4-1.2-0.7-0.6-0.61.8
Time to tail flick, vehicle, after self-admin2.72.95.41.31.3-1.8-1.8-1.5-1.71.52.0-2.0-2.0-1.9-1.42.1-1.61.41.4-1.41.32.2-1.3-2.3-2.11.00.92.3
Time to tail flick, test, before self-admin0.60.62.1-0.9-0.91.00.40.50.8-1.2-0.60.60.60.30.9-0.60.5-0.6-0.80.2-0.90.1-0.1-0.20.41.20.91.4
Time to tail flick, test, after self-admin0.00.10.20.00.1-0.4-0.1-0.1-0.20.40.2-0.2-0.2-0.2-0.20.4-0.00.30.20.20.20.10.2-0.1-0.3-0.0-0.00.3
Delta time to tail flick, vehicle, before/after SA0.80.81.70.50.6-1.0-0.8-0.5-0.90.91.1-1.1-1.1-0.7-0.91.3-0.80.80.9-1.00.91.2-0.4-1.1-1.10.90.90.8
Delta time to tail flick, test, before/after SA1.11.02.81.21.2-1.3-0.6-0.6-1.21.70.9-0.9-0.9-0.4-1.41.0-0.91.01.3-0.31.30.10.10.0-0.7-1.1-0.8-1.4
Tibia length0.92.59.31.61.7-1.9-2.1-2.6-1.21.50.9-0.9-0.9-2.3-0.60.6-0.62.00.30.60.30.7-2.2-0.8-0.7-3.1-3.00.5
Ambulatory time before self-admin0.60.63.70.60.7-0.6-0.9-1.2-0.20.30.3-0.3-0.3-1.00.1-0.10.10.9-0.20.1-0.20.1-1.0-0.20.0-1.9-1.90.1
Ambulatory time after self-admin0.40.41.7-0.4-0.20.30.1-0.20.6-0.7-0.50.50.5-0.00.8-0.80.80.3-0.80.3-0.8-0.60.40.50.8-1.3-1.3-0.1
Bone: tissue strength0.10.10.6-0.00.10.0-0.2-0.30.2-0.2-0.30.30.3-0.20.2-0.30.30.2-0.30.1-0.3-0.2-0.50.10.3-0.8-0.8-0.4
Total heroin consumption4.85.67.72.82.7-2.7-2.6-2.5-2.72.62.4-2.4-2.4-2.3-2.52.5-2.62.42.4-2.62.42.4-2.6-2.3-2.6-0.7-0.40.7
Bone: trabecular number0.60.92.90.90.8-0.9-1.4-1.7-0.40.20.2-0.2-0.2-1.70.10.3-0.31.4-0.3-0.3-0.30.8-1.3-1.0-0.3-1.4-1.51.5
Bone: trabecular spacing0.40.52.1-0.5-0.50.50.91.20.2-0.20.0-0.0-0.01.2-0.20.0-0.0-0.60.4-0.30.4-0.30.70.50.11.41.4-1.2
Bone: trabecular thickness0.60.71.4-0.8-0.70.90.50.31.0-1.2-1.21.21.20.31.1-1.11.0-0.5-1.20.4-1.2-0.70.50.51.1-0.4-0.60.4
Bone: trabecular tissue density3.14.35.8-2.2-2.42.22.32.12.3-2.1-2.22.22.22.22.1-2.32.2-1.7-2.02.2-2.0-2.42.22.32.3-0.1-0.3-1.6
Water consumed over 24 hours0.91.02.21.01.1-1.1-0.5-0.3-1.21.21.3-1.3-1.3-0.2-1.41.1-1.10.51.4-1.41.50.6-0.4-0.4-1.20.10.4-0.9
Number of responses in last shaping day1.21.32.6-1.3-1.21.41.51.61.1-1.0-1.41.41.41.60.8-1.11.0-1.3-0.70.9-0.6-1.20.91.20.70.90.7-0.6