Hub : Genes

Capn1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose intron excision ratio chr1_203299476_203300103 0.04 0.02 2.0e-03 0.02 0 0 0.01 5.6e-03 2.8e-01 2.6e-01 6.3e-02
2 Brain intron excision ratio chr1_203279654_203281166 0.03 0.02 7.8e-04 0.03 0.02 0.01 0.02 5.2e-04 1.2e-02 2.6e-02 7.3e-03
3 Brain intron excision ratio chr1_203280971_203281166 0.03 0.02 3.0e-03 0.01 0.01 0.01 0.01 1.4e-02 4.7e-02 6.1e-02 2.8e-02
4 Brain isoform ratio XM_039103034.1 0.05 0.04 7.3e-04 0.02 0.03 0.03 0.03 2.5e-03 1.3e-03 5.1e-04 1.7e-03
5 Brain gene expression Capn1 0.47 0.13 0.0e+00 0.22 0.2 0.21 0.22 1.9e-20 2.7e-18 3.2e-19 4.5e-20
6 Adipose alternative polyA NM_019152.2 0.11 0.06 2.2e-06 0.05 0.04 0.04 0.04 6.2e-06 9.6e-06 4.4e-05 1.0e-05
7 Adipose alternative polyA XM_039103034.1 0.09 0.05 1.4e-06 0.05 0.04 0.04 0.04 5.9e-06 1.5e-05 1.3e-05 1.6e-05
8 BLA gene expression Capn1 0.24 0.11 7.3e-09 0.1 0.13 0.11 0.13 8.4e-06 1.3e-07 1.8e-06 1.2e-07
9 Adipose gene expression Capn1 0.29 0.1 0.0e+00 0.18 0.19 0.19 0.19 5.6e-20 4.9e-21 1.9e-20 8.1e-21
10 Brain isoform ratio XM_039103025.1 0.05 0.03 8.4e-04 0.01 0.02 0.02 0.02 8.6e-02 5.7e-03 3.1e-03 1.0e-02
11 Liver gene expression Capn1 0.09 0.05 7.8e-07 0.03 0.05 0.04 0.04 3.5e-04 6.4e-06 3.0e-05 3.8e-05
12 NAcc gene expression Capn1 0.56 0.13 0.0e+00 0.31 0.33 0.34 0.34 1.5e-36 3.4e-39 2.7e-41 2.2e-41
13 NAcc alternative polyA NM_019152.2 0.28 0.13 1.1e-13 0.11 0.11 0.12 0.12 1.2e-12 6.1e-13 1.7e-13 2.4e-13
14 Brain intron excision ratio chr1_203299476_203300340 0.07 0.04 4.1e-05 0.01 0.05 0.04 0 1.5e-02 2.5e-05 6.0e-05 1.2e-01
15 pVTA gene expression Capn1 0.18 0.1 1.1e-04 0.07 0.08 0.07 0.07 4.6e-04 2.8e-04 6.6e-04 3.9e-04
16 RMTg gene expression Capn1 0.17 0.1 2.1e-03 0.09 0.11 0.15 0.11 1.7e-03 7.4e-04 9.0e-05 6.3e-04
17 Brain mRNA stability Capn1 0.07 0.04 4.6e-05 0.05 0.04 0.04 0.05 3.3e-05 6.9e-05 5.0e-05 1.9e-05
18 Adipose mRNA stability Capn1 0.1 0.05 4.5e-09 0.04 0.06 0.06 0.06 1.2e-05 2.1e-07 8.5e-07 2.4e-07
19 LHb gene expression Capn1 0.3 0.15 6.2e-04 0.03 0.14 0.11 0.13 5.5e-02 4.3e-04 1.4e-03 4.8e-04
20 NAcc alternative polyA XM_039103034.1 0.29 0.13 5.8e-14 0.11 0.11 0.12 0.12 6.7e-13 6.6e-13 1.3e-13 1.3e-13
21 PL gene expression Capn1 0.38 0.13 0.0e+00 0.16 0.19 0.2 0.2 6.7e-17 2.9e-20 4.7e-22 2.5e-21
22 Adipose isoform ratio NM_019152.2 0.04 0.03 2.2e-03 0.01 0.02 0.03 0.02 1.1e-02 5.2e-03 7.6e-04 5.5e-03
23 PL alternative polyA XM_039103034.1 0.09 0.05 2.9e-05 0.01 0.04 0.05 0.03 6.9e-03 2.9e-05 6.6e-06 2.0e-04
24 PL alternative polyA NM_019152.2 0.09 0.05 3.5e-05 0.02 0.04 0.05 0.03 6.1e-03 3.3e-05 7.0e-06 2.0e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density1.22.04.2-0.70.6-0.60.21.1-1.01.0-2.11.1-1.3-1.6-1.51.11.6-1.61.9-1.7-1.9-1.91.31.7-1.8-1.21.2
Area under the delay curve0.60.62.50.0-0.10.1-0.50.20.1-0.1-0.10.80.1-0.3-0.81.10.3-0.60.2-0.2-0.6-0.51.31.3-1.3-1.61.6
BMI with tail3.711.929.5-2.72.9-2.9-1.12.1-1.81.8-5.42.1-2.2-3.2-3.42.63.2-3.54.6-4.1-4.4-4.43.54.6-4.5-3.73.8
BMI without tail1.42.97.2-1.51.7-1.7-1.30.7-0.50.5-2.61.1-0.4-1.2-1.51.11.3-1.72.2-1.6-2.1-2.01.72.4-2.7-2.32.3
Body weight1.04.317.8-4.14.2-4.2-2.7-0.50.8-0.8-3.7-0.9-0.4-1.0-0.70.31.0-0.61.6-1.5-1.9-1.80.92.3-1.6-1.61.6
Weight adjusted by age0.70.83.3-1.81.8-1.8-0.8-0.90.9-0.9-0.7-1.2-0.1-0.10.5-0.60.10.7-0.60.1-0.10.0-0.7-0.10.50.7-0.7
Bone surface1.62.810.4-2.82.8-2.8-0.30.3-0.30.3-3.2-0.3-1.9-2.2-1.00.72.1-0.91.4-1.8-2.2-2.10.71.6-1.00.00.1
Bone volume1.52.57.6-1.61.5-1.50.50.9-0.90.9-2.80.5-2.1-2.4-1.41.02.3-1.31.7-1.9-2.3-2.21.11.6-1.2-0.10.2
Breakpoint value in progressive ratio session0.80.83.7-1.91.9-1.9-1.0-1.01.2-1.2-1.0-1.1-0.0-0.50.3-0.50.40.6-0.60.3-0.4-0.2-0.40.10.10.4-0.3
Number of licking bursts0.10.10.4-0.70.5-0.5-0.1-0.20.2-0.2-0.4-0.2-0.1-0.40.1-0.30.30.1-0.10.1-0.3-0.2-0.3-0.1-0.00.3-0.3
Context. condit. distance diff. score0.70.82.81.6-1.71.70.81.0-1.11.10.41.2-0.20.1-0.70.9-0.0-0.80.8-0.6-0.0-0.21.00.5-0.3-1.01.0
Locomotion velocity, session 10.20.21.0-0.20.1-0.1-0.8-0.40.4-0.40.4-0.40.81.00.4-0.0-1.00.4-0.30.30.70.60.10.10.2-0.40.3
Locomotion distance, session 10.70.92.4-0.70.8-0.8-0.80.4-0.40.4-1.20.6-0.1-0.4-0.80.70.5-0.91.0-1.1-1.0-1.01.01.4-1.5-1.51.5
Locomotion velocity, session 20.80.93.8-1.91.9-1.9-1.2-0.40.4-0.4-1.5-0.3-0.0-0.5-0.3-0.10.5-0.30.4-0.6-0.9-0.80.10.9-1.0-0.70.7
Locomotion distance, session 20.40.62.0-0.91.0-1.0-1.0-0.1-0.20.2-1.00.30.2-0.2-0.50.20.2-0.60.6-0.7-0.8-0.70.51.1-1.4-1.41.4
Locomotion velocity, session 31.61.83.50.5-0.40.40.31.5-1.51.5-1.31.4-0.9-0.7-1.51.60.8-1.61.9-1.7-1.1-1.31.81.8-1.3-1.71.7
Locomotion distance, session 30.10.10.30.3-0.20.2-0.00.3-0.30.3-0.10.3-0.00.1-0.20.5-0.1-0.20.3-0.3-0.0-0.10.60.4-0.2-0.50.5
Stereotopy head waving bouts, day 31.92.34.20.8-0.80.80.61.7-1.91.9-1.21.6-0.9-0.4-1.71.80.5-1.72.0-2.0-0.9-1.32.01.9-1.3-2.02.0
Stereotopy head waving duration, day 30.81.02.01.0-0.90.90.91.3-1.41.4-0.61.2-0.8-0.4-1.01.00.5-1.21.3-1.3-0.6-0.81.00.9-0.8-0.90.9
Locomotion velocity, session 73.03.35.20.7-0.80.81.01.8-2.12.1-1.52.1-1.5-1.5-2.11.81.6-2.12.2-2.3-1.8-1.92.12.2-2.0-2.12.2
Locomotion distance, session 70.81.14.20.3-0.30.3-0.20.8-0.90.9-0.61.1-0.1-0.1-1.11.00.2-1.01.1-1.1-0.6-0.71.41.5-1.3-2.02.0
Stereotopy head waving bouts, day 70.70.81.90.3-0.30.31.20.9-1.21.2-0.80.8-1.4-1.3-0.80.61.3-0.91.0-1.2-1.1-1.00.50.5-0.60.2-0.1
Stereotopy head waving duration, day 70.50.71.8-1.21.1-1.10.10.1-0.20.2-1.30.1-0.9-1.3-0.3-0.11.3-0.50.7-0.8-1.3-1.1-0.10.3-0.90.4-0.4
Locomotion velocity, session 80.50.61.7-1.11.1-1.1-1.3-0.80.7-0.70.2-1.11.01.20.7-0.5-1.20.8-0.50.30.80.7-0.4-0.10.6-0.20.2
Locomotion distance, session 81.21.83.20.5-0.50.50.61.5-1.61.6-1.21.4-1.0-0.8-1.61.50.8-1.51.7-1.8-1.1-1.31.71.7-1.0-1.71.8
Degree of sensitization distance1.11.12.80.1-0.10.10.11.0-1.01.0-1.01.1-0.5-0.5-1.31.10.6-1.21.4-1.3-0.9-1.01.41.6-1.1-1.71.7
Degree of sensitization stereotypy0.40.51.7-0.80.7-0.70.50.1-0.30.3-1.00.0-1.0-1.3-0.3-0.11.2-0.30.5-0.6-1.0-0.9-0.10.1-0.40.7-0.7
Conditioned locomotion0.40.52.3-1.41.5-1.5-1.0-0.70.6-0.6-0.6-1.00.30.40.5-0.5-0.40.5-0.1-0.10.20.2-0.5-0.00.40.1-0.1
Cocaine response after cond. corrected0.50.62.01.4-1.41.40.10.7-0.50.50.50.90.40.7-0.50.8-0.6-0.60.6-0.30.40.10.80.5-0.3-1.21.1
Cocaine response after cond. not corrected0.50.61.71.3-1.21.20.20.9-0.60.60.30.80.20.6-0.60.9-0.5-0.60.6-0.40.30.00.90.5-0.2-1.11.1
Cocaine response before conditioning0.20.20.8-0.90.9-0.9-0.1-0.30.3-0.3-0.6-0.5-0.4-0.50.2-0.20.50.2-0.3-0.0-0.4-0.2-0.3-0.10.20.7-0.6
Saline control response1.11.45.9-2.42.4-2.4-1.9-1.31.2-1.2-0.9-1.50.80.60.8-0.8-0.60.8-0.50.10.20.2-0.60.10.1-0.20.2
Bone: connectivity density1.11.75.6-1.91.8-1.8-0.50.4-0.40.4-2.40.3-1.0-1.4-1.00.51.4-1.01.4-1.5-1.8-1.70.81.6-1.5-0.91.0
Bone: cortical apparent density0.70.92.4-0.50.6-0.6-1.1-1.61.3-1.30.9-0.81.20.51.2-1.2-0.61.0-1.31.40.60.9-1.0-1.0-0.20.6-0.7
Bone: cortical area0.20.31.1-0.91.0-1.00.10.00.0-0.0-1.0-0.5-0.7-0.50.0-0.10.50.10.3-0.5-0.4-0.4-0.20.10.40.6-0.6
Bone: cortical porosity0.20.20.7-0.30.3-0.3-0.10.3-0.10.1-0.60.4-0.3-0.6-0.40.00.6-0.50.7-0.3-0.7-0.70.10.4-0.9-0.20.3
Bone: cortical porosity0.20.20.7-0.80.8-0.8-0.6-0.10.4-0.4-0.7-0.00.0-0.3-0.0-0.30.3-0.20.4-0.1-0.5-0.5-0.10.3-0.7-0.10.2
Bone: cortical thickness1.93.15.5-2.02.2-2.2-2.2-2.32.2-2.20.5-2.21.71.42.0-1.9-1.51.9-1.81.61.21.4-1.9-1.31.11.0-1.0
Bone: cortical thickness1.51.73.4-0.80.8-0.8-1.7-1.61.6-1.61.1-1.41.81.81.6-1.1-1.81.4-1.51.41.51.5-0.8-0.80.80.3-0.3
Bone: cortical tissue density0.91.22.9-0.60.7-0.7-1.3-1.71.4-1.40.9-0.91.40.71.3-1.3-0.71.1-1.41.50.71.0-1.1-1.1-0.10.7-0.7
Condit. Reinf. active minus inactive responses0.10.10.2-0.40.4-0.4-0.5-0.30.2-0.2-0.20.10.2-0.1-0.0-0.10.1-0.10.00.0-0.3-0.20.10.3-0.5-0.40.4
Condit. Reinf. active-inactive response ratio0.20.20.5-0.10.2-0.2-0.4-0.70.6-0.60.5-0.20.50.20.6-0.7-0.20.4-0.60.70.20.4-0.6-0.6-0.10.4-0.4
Condit. Reinf. active responses0.30.40.7-0.10.1-0.10.20.5-0.60.6-0.80.6-0.6-0.7-0.70.50.7-0.80.7-0.8-0.8-0.80.60.7-0.7-0.60.6
Condit. Reinf. inactive responses1.41.73.00.2-0.30.31.01.6-1.61.6-1.41.2-1.5-1.2-1.61.41.3-1.51.5-1.7-1.3-1.51.31.5-0.8-1.11.1
Incentive salience index mean0.40.40.9-0.60.6-0.6-0.40.3-0.20.2-0.90.5-0.2-0.6-0.60.40.6-0.70.7-0.6-0.9-0.90.60.9-0.9-0.90.9
Condit. Reinf. lever presses0.50.71.9-0.60.6-0.60.00.8-0.60.6-1.40.4-0.9-0.9-0.90.70.9-0.91.0-1.1-1.0-1.10.71.0-0.4-0.60.6
Condit. Reinf. active minus inactive responses0.40.51.20.5-0.40.40.90.8-0.70.7-0.60.6-1.0-1.1-0.80.91.0-0.60.6-0.5-0.8-0.80.80.6-0.10.00.0
Condit. Reinf. active-inactive response ratio2.22.34.80.9-0.90.92.02.0-1.91.9-1.31.3-2.2-1.9-1.81.71.8-1.51.6-1.6-1.4-1.61.51.3-0.3-0.20.3
Condit. Reinf. active responses0.10.20.7-0.00.2-0.20.10.1-0.10.1-0.50.3-0.4-0.8-0.30.30.8-0.30.2-0.1-0.7-0.60.40.4-0.5-0.10.1
Condit. Reinf. inactive responses0.30.41.6-0.60.7-0.7-1.3-1.01.0-1.00.2-0.21.00.40.6-0.6-0.40.4-0.60.70.10.3-0.3-0.2-0.7-0.40.4
Condit. Reinf. lever presses0.60.83.3-1.61.8-1.8-0.3-0.20.4-0.4-1.6-0.7-0.9-1.2-0.20.01.10.10.2-0.4-1.0-0.80.00.50.10.6-0.5
Condit. Reinf. lever reinforcers received0.10.20.7-0.50.6-0.6-0.1-0.20.3-0.3-0.5-0.1-0.4-0.8-0.10.00.8-0.0-0.10.1-0.6-0.40.10.2-0.20.2-0.2
Conditioned reinforcement - actives0.40.41.90.4-0.50.51.40.6-0.70.70.1-0.1-1.2-0.6-0.10.40.60.0-0.6-0.4-0.1-0.2-0.1-0.30.81.2-1.2
Conditioned reinforcement - inactives1.92.18.82.8-2.92.93.01.4-1.31.31.51.2-1.4-0.8-0.71.00.8-0.4-0.50.10.10.00.4-0.60.81.0-1.0
Conditioned locomotion2.22.711.53.3-3.43.43.01.4-1.61.62.01.1-0.90.0-0.20.7-0.0-0.2-1.00.10.80.6-0.0-1.21.21.2-1.2
Patch foraging indifference point 0 sec0.00.10.30.2-0.30.30.50.3-0.50.50.00.3-0.4-0.2-0.10.00.2-0.20.0-0.4-0.1-0.10.00.0-0.2-0.10.1
Patch foraging indifference point AUC1.31.44.8-2.22.2-2.2-1.3-1.61.6-1.6-0.7-1.50.3-0.30.9-0.90.21.0-0.90.8-0.20.1-0.8-0.40.31.3-1.3
Delay disc. indifference point, 0s delay0.91.03.60.4-0.50.5-0.30.6-0.50.50.01.10.1-0.1-1.11.60.2-0.90.5-0.5-0.6-0.61.91.4-1.6-1.91.9
Delay disc. indifference point, 16s delay0.70.71.41.0-1.01.01.00.8-0.80.80.01.2-0.6-0.9-0.90.90.9-0.80.4-0.4-0.8-0.60.90.6-1.1-0.70.7
Delay disc. indifference point, 2s delay0.30.30.70.1-0.30.30.30.7-0.60.6-0.30.6-0.6-0.4-0.70.80.4-0.70.8-0.7-0.5-0.60.90.7-0.5-0.50.5
Delay disc. indifference point, 24s delay0.50.51.30.2-0.20.2-1.0-0.90.7-0.71.0-0.21.11.00.4-0.1-1.00.5-0.90.80.80.8-0.0-0.0-0.1-0.60.6
Delay disc. indifference point, 4s delay0.40.42.00.2-0.30.3-0.70.10.1-0.10.50.70.60.4-0.50.8-0.3-0.5-0.10.0-0.1-0.11.00.9-1.0-1.41.4
Delay disc. indifference point, 8s delay0.50.53.20.00.0-0.0-0.9-0.10.5-0.50.30.40.70.4-0.50.9-0.4-0.2-0.20.30.00.11.11.1-0.8-1.81.8
Indifference point function ln k2.53.514.13.7-3.83.81.82.0-2.22.21.72.30.11.0-1.11.5-0.8-1.31.1-0.80.70.31.40.5-0.4-1.71.6
Indifference point function log k2.53.514.13.7-3.83.81.82.0-2.22.21.72.30.11.0-1.11.5-0.8-1.31.1-0.80.70.31.40.5-0.4-1.71.6
Patch foraging total patch changes 0 sec0.10.10.20.1-0.30.30.1-0.1-0.10.10.4-0.10.20.50.3-0.3-0.40.3-0.40.10.40.4-0.3-0.40.20.1-0.1
Patch foraging total patch changes 12 sec1.21.67.2-2.72.5-2.5-1.7-1.51.5-1.5-1.1-1.30.4-0.40.8-1.10.30.7-0.60.5-0.5-0.2-0.8-0.1-0.40.5-0.5
Patch foraging total patch changes 18 sec0.20.30.9-1.00.9-0.9-0.0-0.1-0.00.0-0.9-0.1-0.6-0.8-0.30.00.8-0.20.2-0.5-0.8-0.70.10.4-0.60.2-0.1
Patch foraging total patch changes 24 sec1.11.33.8-2.01.8-1.8-1.2-1.51.2-1.2-0.2-1.70.60.51.1-1.0-0.61.2-1.20.60.50.7-1.0-0.60.80.9-0.9
Patch foraging total patch changes 6 sec0.20.21.2-1.11.1-1.1-0.8-0.50.3-0.3-0.5-0.40.30.10.1-0.2-0.10.1-0.0-0.2-0.2-0.10.00.4-0.4-0.30.3
Patch foraging time to switch 0 sec1.72.67.8-1.71.6-1.6-0.20.9-0.60.6-2.80.8-1.5-2.2-1.51.02.1-1.51.9-1.6-2.4-2.31.31.9-1.8-1.11.1
Patch foraging water rate 0 sec1.52.57.92.8-2.62.61.50.1-0.40.42.7-0.10.61.60.8-0.4-1.60.9-1.11.02.11.8-0.9-1.72.11.0-1.1
Patch foraging water rate 12 sec2.94.415.13.8-3.63.61.10.0-0.30.33.90.31.72.81.0-0.5-2.71.0-1.11.53.02.5-0.8-2.02.00.5-0.6
Patch foraging water rate 18 sec0.91.25.12.3-2.22.20.60.6-0.80.81.70.70.71.5-0.10.5-1.4-0.1-0.00.11.30.90.4-0.10.8-0.80.8
Patch foraging water rate 24 sec1.11.56.82.6-2.32.31.00.3-0.60.62.10.40.71.50.20.2-1.50.3-0.30.61.71.3-0.0-0.81.30.1-0.2
Patch foraging water rate 6 sec1.52.27.82.8-2.42.40.50.2-0.30.32.60.21.42.30.6-0.2-2.20.6-0.60.92.21.8-0.4-1.11.6-0.10.1
Seeking ratio, delayed vs. immediate footshock0.20.21.00.3-0.10.10.00.1-0.20.2-0.20.7-0.0-0.4-0.40.10.4-0.50.4-0.4-0.5-0.40.30.3-1.0-1.01.0
Distance traveled before self-admin0.30.30.7-0.90.9-0.9-0.1-0.20.3-0.3-0.8-0.4-0.6-0.80.0-0.20.80.00.1-0.0-0.6-0.5-0.30.0-0.00.6-0.6
Distance traveled after self-admin0.30.31.0-0.40.4-0.4-0.0-0.50.7-0.7-0.1-0.4-0.1-0.40.4-0.80.40.3-0.30.4-0.2-0.0-1.0-0.70.21.0-1.0
Extensor digitorum longus weight1.76.734.7-5.85.9-5.9-4.0-2.22.4-2.4-3.4-2.50.5-0.50.7-1.10.40.80.1-0.4-1.3-1.0-0.51.3-0.8-0.40.5
Bone: elastic displacement1.41.64.51.3-1.11.1-0.4-0.60.7-0.72.1-0.61.62.11.1-0.7-2.01.1-1.21.32.01.8-0.8-1.31.40.3-0.3
Bone: elastic work1.11.43.2-0.70.9-0.9-1.7-1.41.3-1.30.8-1.31.71.81.3-0.9-1.81.2-1.11.01.41.3-0.8-0.60.8-0.0-0.0
Bone: endosteal estimation3.06.511.31.3-1.31.32.33.4-3.23.2-2.42.6-2.9-2.2-2.92.92.2-2.93.3-3.4-2.3-2.72.82.6-1.7-1.71.7
Bone: endosteal perimeter3.57.312.91.4-1.51.52.93.6-3.43.4-2.52.6-3.6-2.7-3.03.02.8-3.03.3-3.5-2.6-2.92.82.4-1.4-1.01.1
Epididymis fat weight1.63.77.02.6-2.52.52.62.6-2.52.5-0.22.3-1.8-1.3-2.12.21.3-1.91.8-1.6-1.0-1.32.01.2-0.7-0.90.9
Delta time in closed arm before/after self-admin0.70.72.7-0.20.0-0.0-1.4-0.40.7-0.70.4-0.11.61.50.10.3-1.40.2-0.40.60.90.70.40.5-0.1-1.61.5
Delta time in open arm before/after self-admin0.40.42.4-0.20.2-0.20.7-0.30.4-0.40.1-0.5-0.7-0.80.4-0.60.70.5-0.50.5-0.20.0-0.8-0.80.61.5-1.5
Diff in mean of infusions in LGA sessions0.40.42.0-0.60.6-0.6-0.4-0.81.0-1.00.2-0.90.50.40.4-0.3-0.40.9-1.40.80.50.6-0.4-0.30.80.1-0.1
Delay discount exponential model param0.40.42.00.00.1-0.10.6-0.0-0.20.2-0.0-0.6-0.20.10.7-0.9-0.20.5-0.0-0.00.40.3-1.1-1.11.11.4-1.4
Extinction: sum of active levers before priming1.11.15.3-2.32.2-2.2-1.2-0.80.7-0.7-1.6-0.6-0.2-0.90.1-0.60.80.00.1-0.5-1.1-0.8-0.20.6-1.0-0.10.1
Active lever presses in extinction session 61.11.13.0-1.71.7-1.7-0.4-0.81.0-1.0-0.6-1.7-0.2-0.10.7-0.8-0.01.1-1.00.50.20.3-1.2-0.51.31.4-1.3
Bone: final force0.71.15.6-2.32.4-2.4-1.0-0.30.2-0.2-1.9-0.8-0.6-0.7-0.20.10.7-0.10.5-0.9-0.9-0.90.20.9-0.2-0.00.1
Bone: final moment0.61.04.9-2.12.2-2.2-0.9-0.30.2-0.2-1.9-0.7-0.6-0.7-0.20.00.7-0.10.6-0.9-0.9-0.90.10.8-0.20.00.0
Food consumed during 24 hour testing period0.50.62.2-0.30.2-0.20.3-0.70.6-0.60.6-0.90.00.10.8-0.7-0.21.0-1.10.70.60.7-1.0-1.11.51.2-1.2
Glucose2.43.65.72.0-1.81.81.82.3-2.42.4-1.02.4-1.7-1.4-2.22.11.5-2.22.1-2.2-1.5-1.72.11.7-1.6-1.61.6
Heart weight1.31.86.02.4-2.42.41.31.6-1.61.60.81.8-0.40.1-1.21.40.1-1.20.7-0.8-0.0-0.31.30.6-0.6-1.41.3
Delay discount hyperbolic model param0.40.41.70.10.0-0.00.6-0.0-0.20.2-0.1-0.6-0.20.10.6-0.9-0.10.5-0.10.00.40.3-1.1-1.11.01.3-1.3
Intermittent access intake day 1-15 change0.70.72.20.9-0.90.91.40.1-0.30.30.8-0.4-0.6-0.00.4-0.2-0.00.5-1.10.40.60.5-0.7-1.01.31.5-1.5
Intermittent access intake escalation0.40.41.70.8-0.90.91.30.3-0.50.50.6-0.0-0.7-0.30.00.10.20.2-0.70.10.20.2-0.3-0.60.81.0-1.0
Intermittent access intake escalation 20.60.62.40.4-0.40.40.7-0.40.4-0.40.8-0.7-0.40.00.6-0.5-0.10.8-1.20.70.60.7-0.9-1.01.21.6-1.6
Intermitt. access day 1 inactive lever presses0.70.83.01.7-1.71.71.61.0-0.90.90.71.1-0.7-0.5-0.50.90.5-0.6-0.30.0-0.2-0.20.6-0.1-0.00.2-0.2
Intermitt. access day 15 inactive lever presses1.21.35.41.9-1.81.82.31.3-1.31.30.51.0-1.4-1.0-0.91.31.0-0.7-0.2-0.4-0.4-0.40.80.00.30.5-0.5
Intermitt. access escalation Index1.81.63.51.8-1.81.80.81.3-1.51.50.31.9-0.1-0.1-1.20.90.2-1.31.7-0.9-0.5-0.61.10.7-1.3-1.71.6
Intermittent access day 1 total infusions6.57.513.72.7-2.62.63.13.7-3.53.5-1.13.4-2.6-2.2-3.23.42.3-3.12.6-2.6-2.2-2.53.12.2-1.9-1.81.9
Intermittent access day 15 total infusions4.75.315.23.3-3.33.33.93.2-3.23.20.22.5-2.6-1.7-2.22.71.7-2.01.1-1.7-1.1-1.42.00.9-0.3-0.20.2
Intermittent access terminal intake (last 3 days)4.95.413.22.7-2.72.73.63.3-3.23.2-0.52.5-2.9-2.1-2.52.82.1-2.21.7-2.0-1.5-1.82.31.4-0.5-0.30.4
Intermittent access total infusions5.35.811.22.5-2.52.53.33.3-3.23.2-0.82.8-2.7-2.2-2.72.92.3-2.62.0-2.3-1.9-2.12.51.7-1.2-0.91.0
Intermittent access day 1 locomotion5.25.59.82.2-2.12.12.13.1-2.92.9-1.03.1-1.7-1.5-2.73.01.7-2.92.1-2.3-1.8-2.12.72.1-2.0-2.22.2
Intermittent access day 15 total locomotion3.03.29.02.5-2.62.63.02.4-2.42.40.12.0-2.0-1.5-1.72.21.5-1.60.3-1.3-1.0-1.11.60.7-0.4-0.10.1
Intermittent access total locomotion7.18.115.32.9-2.92.93.73.9-3.83.8-1.03.4-3.1-2.7-3.23.52.7-3.12.2-2.7-2.3-2.63.02.1-1.6-1.21.3
Intermittent access standard deviation0.40.51.81.2-1.21.21.30.6-0.50.50.70.2-0.6-0.2-0.20.40.20.0-0.80.20.30.2-0.1-0.50.80.8-0.8
Left kidney weight0.31.03.21.3-1.41.41.81.3-1.51.5-0.01.0-1.4-0.8-0.80.80.8-0.70.8-1.0-0.5-0.60.70.20.00.2-0.2
Right kidney weight0.20.52.20.5-0.50.51.50.7-0.60.6-0.10.0-1.4-0.9-0.30.60.8-0.10.0-0.4-0.2-0.30.2-0.10.91.1-1.1
Cocaine induced anxiety0.10.10.5-0.10.0-0.00.60.3-0.50.5-0.2-0.2-0.7-0.4-0.10.10.4-0.00.1-0.3-0.2-0.2-0.00.00.40.6-0.6
Post-drug Anxiety0.60.72.9-1.21.2-1.20.0-0.40.2-0.2-0.6-1.2-0.8-0.20.7-0.60.10.7-0.6-0.20.10.0-1.0-0.61.01.7-1.7
Baseline Anxiety1.01.02.7-1.61.6-1.6-1.3-1.21.2-1.2-0.3-1.40.70.70.9-0.8-0.71.0-1.40.50.50.6-0.9-0.40.60.4-0.4
Tail length1.54.56.8-1.51.5-1.5-2.2-2.42.6-2.61.4-2.62.22.22.4-2.0-2.32.5-2.42.42.22.2-2.1-1.72.01.3-1.3
Length with tail1.13.99.1-3.03.0-3.0-2.5-2.32.5-2.5-0.3-2.91.41.41.9-1.7-1.52.1-1.71.51.31.4-1.8-0.91.71.0-1.0
Length without tail0.51.25.5-2.32.3-2.3-1.5-1.01.1-1.1-1.2-1.60.20.20.6-0.5-0.30.8-0.4-0.00.10.1-0.50.20.80.2-0.1
Times rat made contact with spout0.50.51.7-0.70.7-0.7-1.3-1.21.1-1.10.3-0.51.10.50.8-0.9-0.50.5-0.80.90.20.5-0.6-0.4-0.5-0.10.1
Lifetime Intake4.95.510.42.4-2.32.32.93.2-3.13.1-0.92.8-2.4-2.0-2.72.92.0-2.62.1-2.2-1.8-2.12.61.9-1.4-1.31.4
Liver weight, left0.10.20.60.2-0.20.20.00.5-0.30.3-0.30.4-0.3-0.2-0.40.60.2-0.40.7-0.4-0.2-0.40.80.6-0.2-0.20.2
Liver weight, right0.30.41.30.2-0.30.3-0.20.7-0.60.6-0.30.3-0.00.5-0.71.0-0.5-0.50.9-0.80.1-0.21.21.0-0.1-1.11.1
Locomotor activity1.01.55.21.9-1.81.8-0.0-0.20.2-0.22.3-0.01.52.00.6-0.1-1.90.6-1.11.21.91.6-0.3-0.91.2-0.10.1
Locomotor testing distance1.42.47.52.3-2.12.1-0.2-0.20.3-0.32.7-0.02.02.61.0-0.2-2.50.8-1.21.42.42.0-0.4-1.11.2-0.20.1
Locomotor testing rearing0.91.44.72.0-1.91.9-0.1-0.10.1-0.12.20.21.51.90.70.0-1.80.4-1.01.11.71.5-0.1-0.80.7-0.20.1
Locomotion in novel chamber2.32.810.42.6-2.42.43.22.4-2.52.50.41.6-2.2-1.2-1.61.81.2-1.20.7-1.2-0.5-0.71.20.40.40.2-0.2
Locomotion in novel chamber post-restriction1.11.34.22.1-2.12.12.01.5-1.61.60.71.3-0.9-0.5-1.01.10.5-0.80.5-0.5-0.1-0.31.00.30.0-0.20.2
Fecal boli incidents, locomotor time 10.60.62.7-0.30.2-0.21.20.7-0.60.6-1.10.1-1.6-1.4-0.60.61.4-0.30.4-0.8-0.9-0.90.30.20.30.8-0.7
Change in fecal boli incidents, locomotor task0.50.52.90.20.0-0.0-0.80.2-0.30.30.00.50.80.8-0.50.7-0.7-0.60.2-0.40.1-0.10.91.0-0.8-1.71.7
Time >=10cm from walls, locomotor time 15.25.39.10.7-0.80.82.32.9-2.72.7-1.92.1-2.8-2.5-3.03.02.5-2.52.1-2.6-2.4-2.62.82.6-1.3-1.61.6
Bouts of movement, locomotor time 12.02.25.7-1.11.7-1.7-1.3-2.32.4-2.40.4-1.51.10.21.4-1.9-0.31.7-2.01.80.61.1-1.9-1.40.50.8-0.8
Total resting periods, locomotor time 11.21.33.2-0.91.4-1.4-0.8-1.81.8-1.80.1-1.10.6-0.11.0-1.60.11.2-1.51.30.20.6-1.6-1.10.30.7-0.7
Rest time, locomotor task time 10.30.31.91.4-1.11.10.90.6-0.30.30.70.2-0.10.2-0.30.2-0.20.0-0.40.30.50.4-0.2-0.30.80.1-0.2
Distance moved, locomotor task time 10.60.61.5-0.40.1-0.10.00.6-0.90.9-0.90.7-0.7-0.7-0.60.60.7-0.91.2-1.1-1.0-0.90.80.9-1.2-0.80.8
Vertical activity count, locomotor time 10.50.51.71.2-1.31.31.00.8-1.11.10.70.8-0.40.0-0.30.7-0.0-0.40.2-0.50.10.00.60.0-0.0-0.20.2
Time >=10cm from walls, locomotor time 20.20.21.0-0.40.3-0.30.60.2-0.20.2-0.40.1-0.9-1.0-0.20.00.9-0.20.0-0.3-0.7-0.6-0.2-0.1-0.10.7-0.6
Bouts of movement, locomotor time 20.60.62.3-0.60.7-0.7-1.0-1.41.5-1.50.3-0.60.80.10.8-0.8-0.10.8-1.01.10.20.5-0.6-0.5-0.20.3-0.3
Total resting periods, locomotor time 20.30.31.5-0.30.5-0.5-0.8-1.01.2-1.20.2-0.30.6-0.20.5-0.40.20.4-0.80.9-0.10.2-0.3-0.2-0.40.0-0.0
Rest time, locomotor task time 21.01.13.41.8-1.61.61.11.4-0.70.70.31.3-0.4-0.4-1.41.80.4-1.00.4-0.0-0.3-0.51.61.0-0.4-0.80.8
Distance moved, locomotor task time 20.60.72.1-1.31.1-1.1-0.8-1.00.6-0.6-0.1-1.10.20.31.2-1.4-0.40.9-0.40.20.30.5-1.4-0.90.30.9-0.9
Vertical activity count, locomotor time 21.31.53.20.0-0.20.2-0.4-0.90.5-0.51.5-1.11.11.81.6-1.3-1.81.3-1.20.81.71.6-1.5-1.51.41.0-1.0
Light reinforcement 10.30.51.20.4-0.50.5-0.1-0.60.5-0.51.1-0.40.70.70.7-0.6-0.70.7-1.00.90.80.9-0.6-0.80.50.6-0.6
Light reinforcement 20.60.93.90.9-1.01.02.01.2-1.21.2-0.20.5-1.7-1.1-0.80.81.0-0.40.5-0.8-0.4-0.50.40.10.70.7-0.7
Bone: marrow area3.06.611.51.3-1.41.42.23.4-3.23.2-2.42.7-2.8-2.1-2.92.92.2-3.03.4-3.4-2.3-2.72.82.6-1.8-1.81.8
Bone: maximum diameter0.50.83.5-0.50.6-0.61.11.0-0.80.8-1.4-0.1-1.9-1.2-0.70.71.2-0.50.9-1.4-0.9-1.00.30.40.60.8-0.7
Bone: maximum force1.72.910.5-2.42.5-2.5-0.50.6-0.60.6-3.20.1-1.8-2.0-1.21.01.9-1.21.7-2.1-2.3-2.21.22.1-1.3-0.60.7
Bone: maximum moment1.52.69.3-2.22.3-2.3-0.40.6-0.70.7-3.10.1-1.7-1.8-1.21.01.8-1.21.7-2.1-2.1-2.11.21.9-1.2-0.60.7
Mean time between licks in bursts0.81.13.5-0.50.7-0.7-1.9-1.21.3-1.30.7-1.01.81.71.0-0.8-1.70.9-0.80.91.21.1-0.6-0.50.2-0.40.3
Mean num. licks in bursts0.10.20.50.5-0.40.4-0.4-0.40.3-0.30.70.10.70.60.4-0.3-0.60.2-0.40.50.50.5-0.1-0.2-0.3-0.20.2
Cd content in liver0.50.62.31.1-1.21.21.50.4-0.50.50.80.0-0.7-0.3-0.00.40.20.2-0.40.30.40.30.1-0.61.21.2-1.1
Co content in liver2.52.98.51.2-1.31.3-0.6-1.41.2-1.22.9-0.72.22.21.8-1.4-2.21.6-2.02.32.32.3-1.3-2.01.20.7-0.7
Cu content in liver0.10.10.5-0.60.6-0.6-0.3-0.40.3-0.3-0.2-0.00.1-0.40.3-0.60.40.0-0.20.2-0.4-0.2-0.5-0.3-0.70.1-0.1
Fe content in liver0.10.10.3-0.40.4-0.40.10.3-0.20.2-0.5-0.3-0.5-0.2-0.20.30.1-0.00.2-0.5-0.1-0.20.10.30.40.2-0.1
K content in liver1.51.44.1-1.21.3-1.3-0.60.6-0.60.6-2.00.6-0.8-1.0-1.00.91.0-1.11.5-1.5-1.5-1.51.21.6-1.4-1.31.3
Mg content in liver1.81.84.5-0.10.3-0.30.01.0-1.11.1-1.61.4-0.9-1.4-1.31.01.4-1.61.7-1.6-1.8-1.71.41.6-2.1-1.41.5
Mn content in liver0.60.73.3-1.61.8-1.8-0.5-0.50.5-0.5-1.2-1.0-0.6-0.80.2-0.30.70.3-0.1-0.3-0.6-0.5-0.40.10.20.8-0.7
Na content in liver0.30.41.5-1.21.2-1.2-0.5-0.40.6-0.6-0.7-0.9-0.2-0.10.3-0.20.10.4-0.00.1-0.0-0.1-0.4-0.00.60.7-0.7
Rb content in liver0.91.12.71.6-1.51.50.81.1-1.31.30.11.6-0.5-0.5-0.91.10.6-1.20.9-0.9-0.7-0.71.40.8-1.2-0.80.8
Se content in liver0.60.82.80.1-0.00.01.40.8-0.90.9-0.90.4-1.7-1.6-0.70.31.5-0.60.7-0.9-1.1-1.00.00.20.00.8-0.7
Sr content in liver2.82.54.6-2.01.9-1.9-1.3-1.92.0-2.00.4-2.10.90.71.7-1.7-0.81.8-1.61.50.91.1-1.8-1.41.31.7-1.7
Zn content in liver0.30.41.9-1.41.2-1.2-0.7-0.70.6-0.6-0.6-0.40.1-0.40.3-0.50.40.2-0.20.1-0.5-0.3-0.4-0.0-0.60.1-0.0
Bone: minimum diameter2.75.18.91.1-1.21.21.82.7-2.62.6-2.02.6-2.4-2.2-2.52.22.3-2.73.0-2.8-2.4-2.62.32.1-2.3-1.41.5
Time in familiar zone, hab. session 10.50.50.80.5-0.60.60.50.9-0.90.9-0.50.9-0.6-0.6-0.80.80.6-0.90.9-0.7-0.7-0.70.80.7-0.7-0.60.6
Time in novel zone, hab. session 10.70.71.90.4-0.30.3-0.5-0.70.7-0.71.2-0.61.11.40.8-0.4-1.40.9-1.10.91.31.2-0.4-0.60.8-0.10.0
Total zone transitions, hab. session 10.20.21.1-1.11.0-1.0-0.7-0.50.4-0.4-0.5-0.30.2-0.30.2-0.40.30.1-0.10.1-0.4-0.2-0.20.2-0.5-0.10.1
Total locomotion distance, hab. session 10.81.21.90.6-0.60.60.71.2-1.31.3-0.81.3-0.9-0.9-1.31.20.9-1.31.1-1.2-1.0-1.11.31.4-1.0-1.31.3
Locomotion velocity, hab. session 10.40.61.00.1-0.10.10.30.8-0.80.8-0.80.8-0.7-0.8-0.90.70.8-0.91.0-0.9-0.9-0.90.81.0-0.9-0.90.9
Time in familiar zone, hab. session 20.50.52.40.1-0.20.2-0.8-0.40.4-0.40.8-0.51.11.50.6-0.5-1.50.5-0.30.41.20.9-0.4-0.40.6-0.30.3
Time in novel zone, hab. session 20.20.21.0-0.20.3-0.30.2-0.0-0.10.1-0.50.4-0.5-1.0-0.20.21.0-0.40.1-0.2-0.9-0.70.30.3-0.90.1-0.1
Total zone transitions, hab. session 21.31.74.6-1.41.4-1.4-0.90.4-0.50.5-2.00.7-0.5-1.1-1.00.61.1-1.21.4-1.3-1.7-1.61.11.7-2.1-1.61.7
Total locomotion distance, hab. session 21.62.24.60.0-0.00.00.11.3-1.31.3-1.51.6-0.8-1.0-1.71.41.1-1.71.8-1.7-1.6-1.61.82.0-2.0-2.12.1
Locomotion velocity, hab. session 22.12.84.80.2-0.20.20.51.6-1.61.6-1.71.8-1.2-1.4-2.01.71.4-2.02.1-2.0-1.8-1.92.02.2-1.9-2.12.1
Novel to familiar place preference ratio0.60.62.1-1.21.2-1.20.2-0.10.2-0.2-1.2-0.3-1.0-1.4-0.20.11.4-0.1-0.0-0.2-1.1-0.8-0.00.2-0.30.8-0.7
Novelty place preference0.40.41.8-0.80.8-0.80.3-0.10.1-0.1-0.9-0.1-0.9-1.3-0.10.11.3-0.1-0.0-0.1-1.0-0.7-0.00.1-0.30.7-0.7
Time in novel zone, NPP test0.30.31.2-0.70.6-0.60.2-0.10.1-0.1-0.7-0.1-0.7-1.1-0.10.11.1-0.1-0.0-0.1-0.8-0.60.10.1-0.30.6-0.6
Total zone transitions, NPP test0.60.94.0-2.02.0-2.0-1.1-0.40.3-0.3-1.6-0.3-0.2-0.7-0.2-0.00.7-0.30.4-0.6-1.1-0.90.20.9-1.0-0.60.6
Total locomotion distance, NPP test0.60.92.1-0.20.3-0.3-0.20.6-0.60.6-1.00.9-0.4-0.7-1.10.90.7-1.11.0-0.9-1.1-1.11.21.4-1.3-1.41.4
Locomotion velocity, NPP test0.50.71.5-0.30.3-0.3-0.20.5-0.50.5-1.00.8-0.4-0.8-0.90.70.8-0.90.8-0.7-1.0-1.00.91.2-1.2-1.21.2
Intraocular pressure0.71.03.01.4-1.01.01.70.3-0.10.10.8-0.3-0.8-0.30.3-0.30.20.6-1.30.60.60.5-1.1-1.31.71.7-1.7
Delta distance traveled before/after self-admin0.20.20.60.3-0.20.2-0.3-0.40.5-0.50.6-0.20.80.80.3-0.3-0.70.3-0.50.50.60.6-0.3-0.40.3-0.10.1
Delta ambulatory time before/after self-admin0.30.41.20.2-0.10.1-0.6-0.70.6-0.60.7-0.31.11.00.5-0.5-1.00.5-0.70.60.80.8-0.5-0.50.3-0.20.1
Parametrial fat weight2.75.38.72.1-2.22.22.32.9-2.72.7-1.22.9-2.2-2.0-2.72.62.1-2.72.7-2.2-2.0-2.22.72.0-1.8-1.61.6
Pavlov. Cond. lever latency0.30.41.00.6-0.60.60.1-0.40.5-0.51.0-0.30.60.70.6-0.4-0.70.6-0.70.80.80.8-0.4-0.80.50.4-0.5
Pavlov. Cond. magazine entry latency0.60.71.9-0.50.5-0.5-0.00.4-0.30.3-1.20.7-0.7-1.3-0.80.51.3-0.90.9-0.7-1.4-1.20.81.0-1.3-0.60.7
Pavlov. Cond. change in total contacts0.50.52.3-0.30.2-0.20.70.4-0.40.4-0.90.5-1.1-1.5-0.50.21.5-0.60.5-0.5-1.3-1.00.20.3-0.70.4-0.3
Pavlov. Cond. index score0.10.10.4-0.50.5-0.50.1-0.0-0.00.0-0.60.0-0.4-0.7-0.2-0.00.6-0.20.2-0.1-0.6-0.4-0.00.2-0.10.1-0.1
Pavlov. Cond. latency score0.10.20.5-0.30.3-0.30.00.2-0.20.2-0.70.3-0.4-0.6-0.40.20.6-0.40.4-0.4-0.7-0.60.20.5-0.4-0.30.3
Pavlov. Cond. lever contacts0.10.20.4-0.10.1-0.1-0.10.3-0.40.4-0.50.4-0.2-0.3-0.50.40.3-0.50.5-0.4-0.5-0.50.40.6-0.3-0.50.5
Pavlov. Cond. magazine entry number0.20.20.60.6-0.70.7-0.10.5-0.50.50.20.50.30.6-0.30.5-0.5-0.40.4-0.40.30.10.50.4-0.3-0.80.8
Pavlov. Cond. intertrial magazine entries0.30.40.90.9-1.01.00.9-0.00.1-0.10.9-0.0-0.10.00.3-0.5-0.00.4-0.50.60.50.5-0.7-0.90.80.9-0.9
Pavlov. Cond. lever-magazine prob. diff.0.20.20.6-0.70.8-0.8-0.1-0.10.0-0.0-0.8-0.0-0.4-0.8-0.2-0.10.7-0.20.3-0.2-0.7-0.6-0.00.3-0.30.0-0.0
Pavlov. Cond. response bias0.10.10.3-0.40.4-0.40.1-0.20.2-0.2-0.2-0.1-0.2-0.50.1-0.10.50.1-0.10.2-0.3-0.2-0.1-0.10.10.3-0.3
Pavlov. Cond. lever latency0.30.41.60.7-0.90.9-0.3-0.30.3-0.31.30.11.01.00.5-0.4-0.90.3-0.50.80.80.8-0.3-0.6-0.0-0.10.1
Pavlov. Cond. magazine entry latency0.91.04.7-2.22.1-2.1-1.4-0.91.1-1.1-1.3-0.70.0-0.70.3-0.70.60.2-0.00.1-0.9-0.6-0.50.3-0.90.2-0.2
Pavlov. Cond. change in total contacts0.81.24.0-1.61.7-1.70.2-0.20.2-0.2-1.8-0.3-1.4-2.0-0.3-0.11.9-0.20.4-0.5-1.6-1.3-0.10.3-0.60.9-0.8
Pavlov. Cond. index score0.71.03.6-1.91.9-1.9-0.4-0.20.4-0.4-1.7-0.5-0.9-1.4-0.2-0.21.3-0.10.4-0.5-1.3-1.0-0.10.5-0.50.4-0.4
Pavlov. Cond. latency score0.70.93.1-1.61.7-1.7-0.20.00.1-0.1-1.8-0.3-1.0-1.4-0.40.01.3-0.30.6-0.7-1.3-1.10.10.7-0.60.3-0.2
Pavlov. Cond. lever contacts0.20.20.8-0.80.9-0.90.2-0.10.2-0.2-0.7-0.7-0.7-0.50.0-0.10.40.3-0.2-0.2-0.2-0.2-0.3-0.00.70.7-0.6
Pavlov. Cond. magazine entry number1.72.09.23.0-3.03.01.61.4-1.41.41.71.30.11.0-0.71.1-0.9-0.60.3-0.21.00.60.8-0.00.7-0.80.8
Pavlov. Cond. intertrial magazine entries0.40.51.81.3-1.31.31.21.0-0.90.90.30.7-0.5-0.1-0.60.80.1-0.50.4-0.50.1-0.10.50.20.3-0.30.3
Pavlov. Cond. lever-magazine prob. diff.0.81.04.4-2.12.1-2.1-0.6-0.50.5-0.5-1.7-0.6-0.8-1.3-0.1-0.31.2-0.00.3-0.4-1.2-0.9-0.20.5-0.50.4-0.4
Pavlov. Cond. response bias0.50.73.0-1.61.7-1.7-0.4-0.50.6-0.6-1.2-0.9-0.6-0.80.2-0.40.70.4-0.1-0.1-0.6-0.5-0.40.10.10.7-0.7
Time in closed arm before self-admin0.30.41.3-0.20.2-0.20.70.7-0.60.6-0.70.2-1.1-1.1-0.30.11.0-0.40.7-0.6-0.8-0.8-0.00.2-0.20.7-0.7
Time in closed arm after self-admin0.30.31.40.2-0.30.3-0.10.6-0.40.4-0.20.50.20.2-0.60.7-0.1-0.50.3-0.3-0.1-0.20.70.8-0.5-1.21.1
Time in open arm before self-admin0.80.93.30.8-0.80.8-1.2-0.70.4-0.41.20.21.81.70.7-0.3-1.60.3-0.50.51.11.10.0-0.4-0.4-1.21.2
Time in open arm after self-admin0.91.02.10.4-0.30.3-0.3-1.00.8-0.81.3-0.70.90.91.3-1.2-0.91.0-1.01.11.11.2-1.2-1.40.71.0-1.0
Bone: periosteal estimation1.32.86.20.1-0.10.11.62.1-2.02.0-2.21.2-2.4-1.8-1.81.71.8-1.72.2-2.5-1.7-2.01.61.6-0.7-0.50.5
Bone: periosteal perimeter0.81.33.4-0.40.3-0.31.01.4-1.21.2-1.70.6-1.8-1.4-1.11.11.4-1.11.4-1.7-1.3-1.40.91.0-0.4-0.00.1
Bone: post-yield work8.611.821.7-0.60.6-0.62.03.2-3.33.3-4.63.0-4.1-4.5-3.73.04.5-3.84.2-4.3-4.7-4.63.23.6-3.6-1.92.0
Progressive ratio test 1 active lever presses1.01.03.92.0-1.91.91.71.4-1.21.20.61.2-0.8-0.6-0.80.90.6-0.80.6-0.3-0.2-0.30.60.00.00.1-0.1
Progressive ratio test 1 breakpoint0.80.83.51.9-1.81.81.61.2-1.01.00.71.0-0.7-0.4-0.60.60.4-0.60.5-0.1-0.0-0.20.4-0.20.20.3-0.3
Progressive ratio test 1 inactive lever presses0.30.41.71.3-1.31.30.80.6-0.50.50.70.9-0.0-0.1-0.40.50.1-0.50.10.2-0.0-0.00.50.1-0.3-0.40.4
Progressive ratio test 2 active lever presses2.42.68.82.5-2.42.43.02.2-2.22.20.31.7-2.0-1.3-1.41.61.3-1.30.7-1.0-0.7-0.91.20.3-0.00.4-0.4
Progressive ratio test 2 breakpoint2.12.38.72.8-2.82.82.91.9-2.02.01.01.5-1.6-0.8-1.01.30.8-0.90.3-0.6-0.1-0.30.8-0.20.40.6-0.6
Progressive ratio test 2 inactive lever presses4.14.715.63.4-3.53.53.92.8-3.03.00.82.5-2.5-1.7-1.72.01.7-1.80.6-1.3-1.0-1.11.40.3-0.30.4-0.4
Incentive Sensitization - Responses0.70.72.40.9-0.80.81.51.0-1.21.2-0.30.8-1.3-1.0-0.70.81.0-0.70.3-0.8-0.7-0.70.60.3-0.20.3-0.3
Incentive Sensitization - Breakpoint0.80.82.81.1-1.01.01.71.1-1.21.2-0.20.8-1.4-1.0-0.80.81.0-0.70.3-0.8-0.6-0.70.60.2-0.10.4-0.3
Sum of active levers in priming session hrs 5-61.51.54.9-1.21.2-1.20.4-0.91.1-1.1-0.2-1.8-0.7-0.30.8-0.90.21.4-1.50.70.40.5-1.5-1.12.02.2-2.2
Progressive ratio2.32.67.2-1.81.8-1.8-0.50.7-0.70.7-2.70.7-1.3-1.8-1.51.01.8-1.41.6-1.8-2.3-2.11.22.0-2.0-1.61.6
Food seeking constrained by brief footshock0.30.31.0-0.20.4-0.4-0.8-0.50.5-0.50.5-0.51.01.00.7-0.5-1.00.5-0.60.40.70.6-0.4-0.30.2-0.20.1
Seeking ratio, punishment vs. effort2.02.57.61.7-1.71.7-0.1-0.70.7-0.72.8-0.51.82.31.5-1.0-2.21.3-1.51.72.32.2-1.1-1.71.50.8-0.9
Retroperitoneal fat weight2.68.621.14.6-4.64.64.04.0-3.93.90.33.7-2.4-1.5-2.83.01.6-2.83.0-2.2-1.1-1.62.81.4-0.9-1.31.3
Reaction time number correct0.30.41.0-0.60.9-0.9-0.5-0.70.4-0.40.2-1.00.40.80.7-0.5-0.80.8-0.70.10.80.7-0.7-0.40.90.4-0.4
Reaction time mean minus median0.81.14.7-2.22.1-2.1-0.6-0.40.7-0.7-1.8-0.9-0.9-1.4-0.10.11.20.2-0.1-0.3-1.1-0.90.10.6-0.10.5-0.4
Reaction time mean minus median AUC0.40.62.3-1.51.5-1.5-0.6-0.70.8-0.8-0.9-1.1-0.3-0.60.4-0.20.50.6-0.50.2-0.3-0.2-0.30.00.40.7-0.6
Reaction time num false alarms0.40.62.50.7-0.80.8-0.7-0.20.0-0.01.10.11.41.60.5-0.3-1.50.3-0.40.41.11.0-0.2-0.30.1-0.90.8
Reaction time num false alarms AUC0.40.62.3-0.0-0.10.1-1.2-0.60.5-0.50.8-0.31.51.50.7-0.4-1.40.5-0.60.61.00.9-0.3-0.2-0.1-0.90.8
Reaction time trials correct on left0.30.41.0-0.60.9-0.9-0.5-0.70.4-0.40.2-1.00.40.80.7-0.5-0.80.8-0.70.10.80.7-0.7-0.40.90.4-0.4
Reaction time trials on left0.40.51.3-0.71.0-1.0-0.5-0.80.5-0.50.3-1.10.40.80.8-0.5-0.80.9-0.80.20.80.7-0.7-0.51.00.5-0.5
Reaction time mean0.10.20.8-0.20.3-0.30.4-0.10.2-0.2-0.3-0.1-0.7-0.90.10.20.80.1-0.30.1-0.5-0.30.0-0.10.00.6-0.6
Reaction time mean AUC0.20.21.2-0.10.2-0.20.60.1-0.00.0-0.50.1-0.9-1.1-0.10.31.1-0.1-0.2-0.1-0.7-0.50.20.0-0.20.5-0.4
Median of all reaction times0.10.10.70.3-0.20.20.60.2-0.10.1-0.20.2-0.7-0.9-0.10.30.8-0.1-0.10.0-0.5-0.30.1-0.1-0.20.4-0.4
Reaction time omissions0.40.52.2-1.21.5-1.5-0.8-0.90.8-0.8-0.6-0.80.1-0.20.6-0.30.10.6-0.90.2-0.20.1-0.4-0.1-0.10.2-0.2
Reaction time false alarm rate0.30.41.10.6-0.80.8-0.60.1-0.00.00.70.41.11.00.10.0-0.9-0.10.00.30.60.50.20.1-0.4-1.01.0
Reaction time premature initiation rate2.02.78.6-1.91.8-1.8-2.9-2.22.1-2.10.4-1.82.31.91.7-1.5-1.91.5-0.91.41.31.4-1.1-0.60.40.0-0.1
Reaction time premature initiations3.24.610.6-2.52.5-2.5-3.2-2.92.6-2.60.7-2.62.62.32.3-2.1-2.32.2-1.71.71.81.9-1.8-1.11.10.6-0.6
Std. dev. reaction times0.30.41.3-1.11.2-1.2-0.1-0.40.5-0.5-0.9-0.6-0.7-0.90.20.00.80.3-0.40.1-0.6-0.4-0.10.10.10.6-0.6
Reaction time trials completed0.40.51.3-0.71.0-1.0-0.5-0.80.5-0.50.3-1.10.40.80.8-0.5-0.80.9-0.80.20.80.7-0.7-0.51.00.5-0.5
Reaction time trials AUC0.20.40.8-0.50.8-0.8-0.5-0.60.3-0.30.3-0.90.40.80.6-0.4-0.80.7-0.60.10.80.7-0.5-0.30.80.3-0.3
Run reversals in cocaine runway, females1.71.76.6-0.60.6-0.6-1.10.5-0.60.6-1.31.10.4-0.2-1.21.00.3-1.41.4-1.3-1.1-1.21.51.9-2.0-2.62.5
Run reversals in cocaine runway, males1.00.92.80.6-0.50.5-0.1-0.50.6-0.61.3-0.90.81.20.9-0.4-1.21.0-0.91.11.41.2-0.6-1.01.71.1-1.2
Latency to leave start box in cocaine runway1.01.11.90.1-0.30.30.71.1-1.11.1-1.21.2-0.9-1.1-1.21.01.2-1.31.4-1.2-1.3-1.31.21.1-1.2-1.01.0
Latency to leave start box in cocaine runway, F0.20.20.9-0.20.0-0.00.10.2-0.30.3-0.50.6-0.4-0.8-0.3-0.10.8-0.50.7-0.4-0.8-0.70.20.2-1.0-0.00.0
Latency to leave start box in cocaine runway, M0.70.71.30.3-0.30.30.51.1-0.90.9-1.10.6-0.6-0.4-1.21.10.4-0.90.9-0.9-0.6-0.81.21.1-0.3-1.11.1
Std. dev. time between licks in bursts0.60.83.10.5-0.30.3-1.1-0.50.8-0.81.1-0.41.51.80.8-0.4-1.70.6-0.60.91.31.1-0.4-0.50.2-0.40.4
Total sessions with >9 infusions2.42.64.71.6-1.51.51.42.2-2.02.0-0.72.0-1.1-0.8-2.02.10.9-1.91.7-1.6-1.1-1.42.01.5-1.1-1.71.7
Short access day 1 total inactive lever presses1.51.76.12.5-2.22.21.71.6-1.51.50.51.8-0.7-0.5-1.21.50.6-1.30.4-0.8-0.4-0.61.10.4-0.5-0.80.7
Short access day 10 total inactive lever presses0.91.04.72.2-2.22.20.90.7-0.70.71.61.20.50.7-0.10.5-0.6-0.4-0.50.30.70.50.3-0.4-0.0-0.50.4
Short access day 1 total infusions3.84.07.02.0-1.91.91.92.5-2.42.4-0.82.6-1.6-1.5-2.42.21.6-2.42.3-1.9-1.7-1.82.21.8-1.8-1.91.9
Short access day 10 total infusions6.16.710.11.4-1.41.42.13.1-3.03.0-1.93.0-2.3-2.3-3.23.22.4-3.02.7-2.8-2.5-2.73.22.8-2.4-2.52.5
Short access total infusions3.43.86.21.4-1.31.31.62.5-2.42.4-1.22.3-1.6-1.4-2.42.51.5-2.32.1-2.1-1.7-1.92.42.1-1.7-2.02.0
Short access day 1 locomotion3.13.36.01.7-1.81.81.82.4-2.42.4-0.72.4-1.4-1.1-2.02.21.2-2.21.5-1.9-1.3-1.62.11.6-1.5-1.71.7
Short access day 10 total locomotion2.42.75.01.5-1.41.41.42.1-2.02.0-0.82.2-1.2-1.2-1.91.81.3-2.01.6-1.7-1.4-1.61.61.3-1.6-1.51.6
Short access total locomotion2.42.54.61.3-1.31.31.22.0-1.91.9-0.82.1-1.1-1.0-1.81.91.1-2.01.4-1.7-1.3-1.51.81.4-1.6-1.61.6
One hour access (0.3 mA shock)3.84.414.33.7-3.83.83.72.9-2.82.81.22.3-1.9-1.0-1.72.21.0-1.50.8-0.9-0.3-0.71.50.30.30.1-0.1
Compulsive drug intake3.73.89.6-1.81.7-1.7-3.1-2.72.7-2.70.9-1.92.82.12.1-2.4-2.11.9-0.92.01.61.8-1.8-1.20.60.1-0.2
One hour access (shock baseline)4.85.619.83.6-3.53.54.53.3-3.13.10.52.4-3.1-2.0-2.12.62.0-1.80.8-1.5-1.0-1.31.70.50.20.6-0.6
Social response proportion0.30.31.3-1.21.0-1.0-0.4-0.40.6-0.6-0.7-0.6-0.2-0.40.2-0.40.30.3-0.30.1-0.3-0.2-0.5-0.1-0.00.4-0.4
Social responses0.30.40.8-0.60.5-0.5-0.6-0.70.8-0.80.2-0.90.50.60.6-0.7-0.60.7-0.80.70.60.6-0.9-0.50.80.4-0.4
Social time0.50.61.1-0.70.9-0.9-0.8-0.90.8-0.80.2-1.00.70.90.9-0.7-0.90.9-0.80.60.80.7-0.8-0.70.70.6-0.6
Soleus weight1.23.513.63.7-3.73.72.62.3-2.32.31.12.3-1.0-0.2-1.41.50.3-1.51.3-0.90.1-0.31.20.4-0.1-0.80.8
Bone: stiffness1.42.37.6-2.22.2-2.2-0.30.4-0.50.5-2.80.1-1.6-2.0-1.00.62.0-1.01.4-1.6-2.2-2.00.91.6-1.3-0.30.4
Tibialis anterior weight2.89.643.2-6.56.6-6.6-4.0-3.33.3-3.3-2.7-4.30.90.52.0-2.2-0.72.4-1.40.50.10.3-2.1-0.11.41.1-1.0
Time to tail flick, vehicle, before self-admin0.90.92.2-0.90.8-0.80.00.5-0.80.8-1.30.3-1.0-0.9-1.11.10.9-0.70.7-1.3-1.0-1.11.31.5-0.7-1.01.0
Time to tail flick, vehicle, after self-admin0.91.02.5-1.31.3-1.3-1.30.2-0.00.0-1.40.20.1-0.1-0.70.50.1-0.71.2-0.9-0.8-0.91.01.5-1.3-1.61.6
Time to tail flick, test, before self-admin2.42.34.90.9-0.80.80.51.6-1.71.7-0.71.8-0.7-0.6-1.81.80.7-1.81.7-1.7-1.1-1.32.11.9-1.7-2.22.2
Time to tail flick, test, after self-admin0.10.10.2-0.00.2-0.2-0.1-0.20.2-0.20.2-0.40.10.30.2-0.3-0.30.3-0.30.00.30.3-0.2-0.10.40.2-0.2
Delta time to tail flick, vehicle, before/after SA0.20.21.0-0.50.7-0.7-1.0-0.10.5-0.5-0.50.00.60.2-0.1-0.1-0.2-0.20.50.0-0.2-0.20.20.5-0.7-0.80.7
Delta time to tail flick, test, before/after SA4.13.76.9-1.21.2-1.2-0.9-2.22.1-2.11.1-2.41.01.12.3-2.4-1.22.4-2.21.91.61.8-2.6-2.32.12.5-2.5
Tibia length0.51.33.8-1.81.8-1.80.5-0.20.4-0.4-1.5-1.4-1.6-1.30.2-0.41.20.6-0.3-0.3-0.6-0.6-0.8-0.31.32.0-1.9
Ambulatory time before self-admin0.40.41.5-0.60.7-0.70.50.2-0.00.0-1.0-0.2-1.1-1.2-0.40.21.1-0.10.2-0.2-0.8-0.7-0.00.20.10.7-0.7
Ambulatory time after self-admin0.40.41.50.4-0.30.31.00.5-0.30.3-0.50.6-1.0-1.2-0.60.21.2-0.60.4-0.3-0.9-0.8-0.00.0-0.40.5-0.4
Bone: tissue strength0.10.10.40.10.1-0.10.50.2-0.40.4-0.50.1-0.6-0.6-0.30.10.6-0.20.2-0.5-0.5-0.40.00.2-0.00.1-0.1
Total heroin consumption1.61.97.6-2.72.8-2.8-2.0-1.71.6-1.6-1.1-1.60.4-0.11.2-1.5-0.01.0-0.60.3-0.30.1-1.3-0.3-0.10.6-0.6
Bone: trabecular number1.11.74.0-0.90.7-0.70.61.0-1.01.0-2.00.8-1.7-1.9-1.30.91.8-1.21.6-1.5-1.8-1.81.01.4-1.1-0.60.6
Bone: trabecular spacing0.40.51.50.5-0.50.5-0.7-0.60.5-0.51.2-0.11.21.10.6-0.4-1.10.5-0.70.80.90.9-0.3-0.4-0.1-0.30.3
Bone: trabecular thickness0.70.91.60.8-0.90.91.01.1-1.01.0-0.61.3-1.0-1.1-1.10.81.1-1.11.1-0.8-1.0-1.00.80.7-0.9-0.50.5
Bone: trabecular tissue density0.81.15.72.3-2.42.41.71.0-0.90.91.21.0-0.40.0-0.30.50.0-0.30.10.20.40.30.2-0.60.50.4-0.5
Water consumed over 24 hours1.41.63.2-1.01.1-1.1-1.4-1.81.8-1.80.8-1.31.40.81.5-1.5-0.91.4-1.61.60.81.1-1.4-1.20.60.8-0.9
Number of responses in last shaping day0.50.51.61.3-1.31.30.40.2-0.10.11.20.20.50.80.4-0.1-0.80.2-0.60.50.90.7-0.3-0.70.50.3-0.3