Hub : Genes

Peli3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver intron excision ratio chr1_211667895_211670909 0.04 0.03 5.5e-03 0.01 0.01 0.01 0.01 2.4e-02 9.4e-03 5.4e-02 7.3e-03
2 Liver intron excision ratio chr1_211670769_211670909 0.05 0.03 1.6e-04 0.01 0.01 0.01 0.01 1.7e-02 2.7e-02 1.7e-02 2.3e-02
3 Liver mRNA stability Peli3 0.08 0.07 6.2e-05 0 0.02 0.03 0.01 1.3e-01 9.3e-04 2.8e-04 1.5e-02
4 NAcc alternative TSS XM_039079453.1 0.02 0.02 3.9e-03 0.01 0.01 0 0.01 1.1e-02 8.0e-03 5.0e-02 3.4e-02
5 Adipose gene expression Peli3 0.27 0.12 0.0e+00 0.14 0.14 0.14 0.14 2.7e-15 7.2e-15 6.3e-15 4.2e-15
6 Liver gene expression Peli3 0.19 0.08 0.0e+00 0.12 0.14 0.13 0.13 7.2e-13 6.5e-15 1.2e-14 2.6e-14
7 BLA mRNA stability Peli3 0.08 0.06 1.6e-03 0.04 0.03 0.03 0.03 4.0e-03 1.2e-02 8.7e-03 1.2e-02
8 BLA gene expression Peli3 0.13 0.08 1.2e-04 0.07 0.06 0.03 0.06 1.6e-04 5.7e-04 7.1e-03 6.9e-04
9 IL gene expression Peli3 0.25 0.17 5.6e-03 0.02 0.03 0.04 0 1.2e-01 7.7e-02 4.1e-02 3.0e-01
10 pVTA mRNA stability Peli3 0.06 0.04 2.3e-03 0.01 0.02 0.02 0.01 2.6e-02 7.5e-03 5.2e-03 2.3e-02
11 IC mRNA stability Peli3 0.19 0.1 2.8e-06 0.12 0.12 0.11 0.11 1.1e-05 8.5e-06 1.9e-05 2.4e-05
12 NAcc mRNA stability Peli3 0.03 0.02 6.6e-04 0.02 0.02 0.01 0.02 6.2e-04 1.6e-04 5.3e-03 1.9e-04
13 PL mRNA stability Peli3 0.06 0.04 1.6e-05 0.04 0.05 0.03 0.04 1.9e-05 8.1e-06 2.8e-04 2.9e-05
14 NAcc isoform ratio NM_001127542.1 0.03 0.02 5.7e-04 0.01 0.02 0.02 0.01 2.1e-02 1.1e-03 1.1e-03 4.2e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bone: apparent density2.34.06.41.0-0.90.12.5-1.6-1.32.42.52.12.22.22.42.5-2.4
Area under the delay curve0.60.61.2-0.20.70.30.7-0.8-0.90.40.60.80.71.11.01.0-1.1
BMI with tail2.89.620.42.4-2.32.14.5-1.4-1.03.93.72.63.62.93.43.8-3.6
BMI without tail1.13.28.71.6-1.61.82.9-0.2-0.22.02.01.11.91.51.92.2-2.1
Body weight1.25.213.23.6-3.53.53.61.31.72.32.20.11.40.30.91.5-1.2
Weight adjusted by age0.71.03.11.7-1.71.40.81.31.40.50.5-0.7-0.2-0.8-0.5-0.40.5
Bone surface3.36.113.03.1-2.92.13.6-0.40.13.23.31.72.81.52.12.5-2.2
Bone volume2.34.17.91.8-1.70.72.7-1.2-0.72.72.81.92.31.72.12.3-2.1
Breakpoint value in progressive ratio session1.31.55.22.3-1.81.51.61.11.21.41.4-0.10.9-0.30.20.4-0.2
Number of licking bursts0.10.20.60.7-0.60.80.6-0.10.30.60.60.20.50.10.20.3-0.2
Context. condit. distance diff. score0.70.93.8-1.61.2-2.0-1.0-0.9-1.1-0.7-0.60.3-0.40.50.1-0.1-0.1
Locomotion velocity, session 10.50.51.2-0.00.20.6-0.50.50.6-1.1-1.1-0.9-0.9-0.7-0.8-0.80.8
Locomotion distance, session 10.91.22.50.7-0.20.91.6-0.7-0.51.21.01.01.01.21.31.4-1.4
Locomotion velocity, session 21.01.23.61.9-1.81.91.60.91.00.60.6-0.30.4-0.10.20.5-0.3
Locomotion distance, session 20.50.72.31.0-0.51.51.5-0.00.10.90.60.40.40.60.81.0-0.9
Locomotion velocity, session 30.30.40.7-0.30.30.10.4-0.8-0.80.40.40.80.30.80.80.8-0.8
Locomotion distance, session 30.00.00.2-0.00.10.5-0.0-0.1-0.00.00.10.1-0.20.00.00.0-0.0
Stereotopy head waving bouts, day 30.50.61.7-1.11.3-0.30.0-0.9-1.20.00.00.70.11.00.80.7-0.8
Stereotopy head waving duration, day 30.70.92.0-1.31.3-0.9-0.1-1.2-1.40.20.11.00.41.10.90.8-0.9
Locomotion velocity, session 70.60.71.3-0.40.2-0.50.7-0.8-1.00.70.60.91.01.11.11.1-1.1
Locomotion distance, session 70.10.10.3-0.0-0.30.20.50.1-0.10.00.0-0.00.20.30.30.4-0.4
Stereotopy head waving bouts, day 71.01.11.9-0.1-0.1-0.30.7-1.2-1.11.31.31.41.31.21.21.2-1.2
Stereotopy head waving duration, day 71.51.83.91.0-1.10.61.6-0.7-0.62.01.91.31.71.21.41.5-1.4
Locomotion velocity, session 80.50.71.91.2-1.01.40.51.11.1-0.2-0.3-0.8-0.5-0.7-0.6-0.40.5
Locomotion distance, session 80.20.30.7-0.60.6-0.8-0.0-0.8-0.80.1-0.10.5-0.00.60.50.4-0.5
Degree of sensitization distance0.20.30.5-0.0-0.2-0.10.7-0.2-0.40.40.30.40.70.60.70.7-0.7
Degree of sensitization stereotypy0.80.81.80.8-1.10.21.0-0.4-0.31.41.30.81.20.60.80.8-0.8
Conditioned locomotion1.11.33.51.4-1.51.40.61.91.7-0.0-0.2-1.3-0.5-1.1-0.9-0.70.7
Cocaine response after cond. corrected0.40.51.7-1.31.1-1.2-1.0-0.4-0.5-0.7-0.6-0.1-0.50.0-0.2-0.40.3
Cocaine response after cond. not corrected0.30.41.3-1.01.1-0.9-0.7-0.6-0.7-0.4-0.30.3-0.10.20.0-0.10.0
Cocaine response before conditioning0.30.41.21.1-0.60.90.9-0.20.10.70.70.50.80.20.50.5-0.4
Saline control response1.41.86.62.6-2.02.51.90.91.30.80.9-0.30.7-0.20.20.6-0.3
Bone: connectivity density2.94.510.22.1-1.91.43.2-0.6-0.42.62.61.62.51.82.22.5-2.3
Bone: cortical apparent density0.40.51.00.4-0.40.6-0.31.00.9-0.6-0.6-1.0-0.6-0.9-0.9-0.80.8
Bone: cortical area0.30.51.71.3-1.10.50.30.81.00.00.1-0.6-0.3-0.7-0.5-0.40.5
Bone: cortical porosity0.50.50.90.2-0.30.00.9-0.5-0.40.90.80.70.50.80.90.9-0.9
Bone: cortical porosity0.40.41.10.6-0.70.31.1-0.1-0.10.80.80.40.40.50.60.8-0.7
Bone: cortical thickness3.05.010.02.6-2.62.40.33.13.2-1.0-1.1-2.6-1.6-2.6-2.2-1.82.0
Bone: cortical thickness1.92.24.00.9-1.01.9-0.22.01.9-1.2-1.3-1.9-1.5-1.6-1.6-1.31.4
Bone: cortical tissue density0.50.71.40.5-0.60.8-0.31.21.0-0.6-0.6-1.1-0.6-1.0-0.9-0.90.9
Condit. Reinf. active minus inactive responses0.30.40.70.6-0.50.60.8-0.4-0.10.90.80.60.70.50.60.6-0.6
Condit. Reinf. active-inactive response ratio0.20.20.60.4-0.30.10.5-0.4-0.30.70.70.60.80.40.50.4-0.4
Condit. Reinf. active responses0.20.20.50.5-0.40.30.6-0.3-0.10.70.70.40.50.30.40.4-0.4
Condit. Reinf. inactive responses0.00.00.1-0.10.1-0.20.2-0.2-0.20.30.20.2-0.00.30.20.2-0.2
Incentive salience index mean0.40.51.10.8-0.80.51.1-0.3-0.10.90.90.50.80.50.70.8-0.7
Condit. Reinf. lever presses0.20.20.90.9-0.90.10.70.10.30.70.50.10.40.00.20.3-0.2
Condit. Reinf. active minus inactive responses1.01.22.6-0.10.5-0.50.5-1.5-1.21.31.31.61.21.21.31.1-1.1
Condit. Reinf. active-inactive response ratio1.01.22.8-0.71.1-1.2-0.2-1.7-1.50.80.81.51.01.11.00.8-0.8
Condit. Reinf. active responses1.62.23.50.4-0.10.21.4-1.5-1.21.81.81.91.61.61.81.8-1.7
Condit. Reinf. inactive responses1.01.33.00.7-0.91.11.7-0.5-0.41.41.31.01.01.11.31.5-1.4
Condit. Reinf. lever presses1.21.73.92.0-1.61.41.9-0.20.21.71.70.91.00.61.01.1-1.0
Condit. Reinf. lever reinforcers received1.41.93.30.7-0.40.51.5-1.3-0.91.81.81.71.41.41.61.7-1.6
Conditioned reinforcement - actives0.10.10.20.10.1-0.5-0.40.00.2-0.1-0.1-0.1-0.3-0.4-0.4-0.40.5
Conditioned reinforcement - inactives0.91.34.0-1.81.6-2.0-1.3-1.6-1.6-0.2-0.21.00.10.70.40.0-0.2
Conditioned locomotion3.34.212.5-3.33.4-3.5-2.8-2.1-2.1-1.7-1.70.6-1.10.5-0.1-0.70.4
Patch foraging indifference point 0 sec0.20.30.8-0.20.6-0.30.2-0.9-0.70.30.20.80.60.70.70.6-0.6
Patch foraging indifference point AUC0.91.34.11.9-2.01.50.91.61.60.70.6-0.80.2-0.9-0.6-0.30.5
Delay disc. indifference point, 0s delay0.70.71.5-0.81.2-0.30.3-1.2-1.2-0.1-0.10.80.21.20.90.9-1.0
Delay disc. indifference point, 16s delay0.91.02.0-0.81.2-0.70.1-1.4-1.40.50.71.31.01.21.10.9-1.0
Delay disc. indifference point, 2s delay0.30.41.0-0.40.6-0.30.1-1.0-0.80.20.20.80.40.70.70.6-0.6
Delay disc. indifference point, 24s delay0.30.30.8-0.30.40.3-0.40.60.3-0.9-0.7-0.8-0.5-0.4-0.5-0.50.5
Delay disc. indifference point, 4s delay0.30.30.6-0.40.70.10.4-0.6-0.70.00.20.40.30.80.70.7-0.8
Delay disc. indifference point, 8s delay0.20.20.5-0.30.70.40.4-0.4-0.50.00.20.30.20.70.60.6-0.7
Indifference point function ln k2.84.915.8-3.64.0-3.0-2.8-1.9-2.0-2.3-2.30.3-1.70.5-0.2-0.70.4
Indifference point function log k2.84.915.8-3.64.0-3.0-2.8-1.9-2.0-2.3-2.30.3-1.70.5-0.2-0.70.4
Patch foraging total patch changes 0 sec0.00.00.2-0.00.5-0.0-0.2-0.2-0.1-0.3-0.40.1-0.10.10.0-0.00.0
Patch foraging total patch changes 12 sec1.82.37.22.7-2.52.22.21.51.41.31.2-0.41.0-0.20.30.6-0.4
Patch foraging total patch changes 18 sec0.40.61.20.9-1.10.91.10.30.21.00.90.31.00.30.50.7-0.6
Patch foraging total patch changes 24 sec0.71.13.41.9-1.41.70.71.61.50.20.2-0.9-0.1-0.9-0.6-0.40.6
Patch foraging total patch changes 6 sec0.71.03.01.7-1.51.41.50.40.51.11.00.20.90.30.50.7-0.6
Patch foraging time to switch 0 sec1.93.88.01.6-1.71.42.8-0.6-0.42.52.71.52.51.62.02.2-2.1
Patch foraging water rate 0 sec2.55.312.6-2.62.8-2.6-3.6-0.2-0.3-2.9-3.0-1.2-2.5-1.3-1.9-2.32.1
Patch foraging water rate 12 sec4.08.417.9-3.94.1-3.2-4.2-0.7-0.9-3.8-3.9-1.2-3.3-1.1-1.9-2.42.1
Patch foraging water rate 18 sec1.52.35.6-2.02.4-1.6-2.2-0.6-0.7-2.1-2.1-0.5-1.7-0.4-0.9-1.21.0
Patch foraging water rate 24 sec3.34.610.4-2.62.7-2.5-3.2-0.1-0.4-2.8-2.9-1.2-2.3-1.1-1.7-2.01.8
Patch foraging water rate 6 sec3.55.010.3-2.42.9-2.0-3.20.0-0.2-2.9-3.1-1.3-3.0-1.3-1.9-2.22.0
Seeking ratio, delayed vs. immediate footshock0.70.91.5-0.10.30.10.8-1.2-1.00.90.91.20.81.21.21.1-1.2
Distance traveled before self-admin0.50.61.20.8-0.50.41.0-0.4-0.31.11.10.81.00.70.80.9-0.8
Distance traveled after self-admin0.10.20.40.5-0.50.50.4-0.10.00.60.60.30.40.10.30.3-0.2
Extensor digitorum longus weight3.011.835.66.0-5.95.53.74.14.41.61.3-2.20.1-2.1-1.0-0.20.7
Bone: elastic displacement2.22.54.4-0.80.6-0.3-1.91.21.0-2.0-2.1-1.7-1.9-1.7-1.9-2.01.9
Bone: elastic work1.82.44.41.3-1.31.8-0.22.12.1-1.2-1.1-1.9-1.3-1.8-1.6-1.41.5
Bone: endosteal estimation1.53.26.7-1.41.8-1.70.4-2.6-2.41.01.22.21.32.22.01.8-1.9
Bone: endosteal perimeter2.75.711.8-1.52.3-1.80.5-3.4-3.11.91.93.22.02.82.72.3-2.4
Epididymis fat weight1.65.520.2-3.83.6-4.5-2.7-2.7-2.8-1.1-1.21.3-0.31.10.5-0.1-0.1
Delta time in closed arm before/after self-admin0.60.61.60.6-0.90.70.21.30.9-0.6-0.7-1.1-0.8-0.7-0.7-0.50.5
Delta time in open arm before/after self-admin0.10.10.40.4-0.6-0.00.2-0.00.10.60.60.30.6-0.10.10.1-0.0
Diff in mean of infusions in LGA sessions0.30.41.21.0-1.10.20.41.10.90.20.3-0.60.3-0.6-0.4-0.30.3
Delay discount exponential model param0.40.40.80.1-0.6-0.4-0.60.60.7-0.3-0.5-0.6-0.6-0.9-0.9-0.90.9
Extinction: sum of active levers before priming1.51.63.71.9-1.51.01.90.40.51.81.80.51.50.50.91.1-0.9
Active lever presses in extinction session 61.21.24.11.9-2.01.31.11.11.31.11.1-0.30.5-0.7-0.3-0.10.2
Bone: final force0.71.24.62.1-1.71.81.50.91.20.80.7-0.30.1-0.30.00.3-0.1
Bone: final moment0.71.14.22.1-1.71.71.40.81.10.80.7-0.20.1-0.30.10.3-0.1
Food consumed during 24 hour testing period0.20.20.50.2-0.1-0.2-0.60.20.4-0.5-0.4-0.4-0.5-0.6-0.6-0.70.7
Glucose2.33.67.7-2.02.1-1.70.1-2.7-2.80.70.72.21.32.42.01.8-2.0
Heart weight1.82.85.1-1.31.0-1.30.8-2.1-2.20.80.91.81.42.32.02.0-2.1
Delay discount hyperbolic model param0.40.50.90.2-0.6-0.4-0.60.70.8-0.4-0.5-0.7-0.6-0.9-0.9-0.90.9
Intermittent access intake day 1-15 change0.40.83.2-1.21.3-1.8-1.4-0.6-0.6-0.7-0.70.1-0.4-0.2-0.4-0.70.6
Intermittent access intake escalation0.30.72.4-1.11.1-1.6-1.4-0.4-0.4-0.7-0.7-0.0-0.4-0.3-0.5-0.80.7
Intermittent access intake escalation 20.70.83.0-1.21.1-1.7-1.5-0.3-0.4-0.8-0.8-0.1-0.5-0.4-0.6-0.80.7
Intermitt. access day 1 inactive lever presses0.00.00.2-0.40.1-0.2-0.3-0.1-0.20.20.20.20.30.00.0-0.10.1
Intermitt. access day 15 inactive lever presses0.51.02.2-1.21.1-1.1-0.5-1.5-1.50.60.61.30.91.00.90.6-0.7
Intermitt. access escalation Index1.52.16.4-2.22.3-2.5-1.1-1.7-1.8-0.9-0.90.8-0.41.10.60.4-0.6
Intermittent access day 1 total infusions3.15.09.9-1.61.5-2.20.7-3.1-3.01.41.42.81.92.82.62.4-2.5
Intermittent access day 15 total infusions2.13.210.6-2.32.3-3.3-1.2-2.6-2.50.10.11.80.71.51.20.8-0.9
Intermittent access terminal intake (last 3 days)2.63.59.3-2.11.9-3.0-0.7-2.7-2.70.60.62.11.21.91.61.2-1.4
Intermittent access total infusions3.03.67.6-1.71.6-2.50.1-2.8-2.61.01.02.31.42.22.01.7-1.8
Intermittent access day 1 locomotion2.33.05.9-1.41.1-1.40.4-2.4-2.41.11.12.11.52.22.01.8-1.9
Intermittent access day 15 total locomotion1.83.28.0-2.12.1-2.8-0.8-2.8-2.60.50.52.11.11.81.51.1-1.2
Intermittent access total locomotion5.05.913.8-2.52.6-3.5-0.5-3.7-3.50.90.92.91.52.62.31.8-2.0
Intermittent access standard deviation0.30.61.6-1.31.1-1.3-1.2-0.6-0.6-0.7-0.70.1-0.5-0.1-0.3-0.50.4
Left kidney weight0.41.87.1-2.02.0-2.7-1.4-1.4-1.5-1.1-1.10.4-0.80.60.1-0.1-0.0
Right kidney weight0.31.53.9-1.51.6-2.0-1.8-0.6-0.5-1.5-1.5-0.4-1.2-0.4-0.7-0.90.8
Cocaine induced anxiety0.00.10.20.1-0.30.20.2-0.10.00.40.40.20.20.10.20.1-0.1
Post-drug Anxiety0.20.30.80.8-0.90.90.50.50.60.50.5-0.10.1-0.3-0.10.00.1
Baseline Anxiety0.30.30.60.6-0.40.50.00.80.7-0.5-0.5-0.8-0.6-0.6-0.6-0.40.5
Tail length0.72.85.81.3-1.21.5-0.32.42.2-1.2-1.2-2.2-1.8-1.9-1.8-1.61.7
Length with tail1.14.910.73.0-2.82.90.93.23.3-0.4-0.4-2.4-1.4-2.3-1.9-1.41.7
Length without tail1.13.78.22.7-2.52.90.82.62.8-0.3-0.4-1.9-1.1-2.0-1.6-1.11.4
Times rat made contact with spout0.40.41.10.8-0.71.01.00.30.20.70.80.10.70.30.50.6-0.5
Lifetime Intake2.32.75.6-1.41.3-2.20.2-2.4-2.30.90.92.01.22.01.81.6-1.7
Liver weight, left0.81.33.1-1.41.1-1.1-1.50.3-0.0-1.7-1.8-0.9-1.3-0.6-1.0-1.00.9
Liver weight, right0.91.54.6-2.11.9-1.4-1.6-0.7-0.8-1.5-1.7-0.3-1.2-0.0-0.5-0.60.4
Locomotor activity1.62.45.5-1.71.9-1.0-2.10.0-0.0-2.3-2.3-1.1-2.0-0.9-1.3-1.51.3
Locomotor testing distance1.73.17.3-2.02.3-1.1-2.3-0.1-0.1-2.7-2.6-1.2-2.2-0.9-1.4-1.51.4
Locomotor testing rearing0.71.34.4-2.12.1-1.3-1.3-0.9-1.1-1.4-1.40.0-1.00.3-0.1-0.20.0
Locomotion in novel chamber2.22.97.9-2.62.8-2.8-2.0-2.1-2.1-1.2-1.30.9-0.60.80.3-0.1-0.1
Locomotion in novel chamber post-restriction1.11.86.9-2.01.9-2.6-1.4-1.6-1.6-0.8-0.70.7-0.20.70.30.0-0.2
Fecal boli incidents, locomotor time 10.10.10.5-0.3-0.5-0.3-0.2-0.00.00.40.50.20.7-0.1-0.0-0.10.1
Change in fecal boli incidents, locomotor task0.10.10.30.20.50.30.4-0.3-0.3-0.1-0.10.20.00.50.40.5-0.5
Time >=10cm from walls, locomotor time 12.72.95.4-0.90.7-0.90.7-2.3-2.11.51.52.31.82.02.01.8-1.8
Bouts of movement, locomotor time 10.50.61.91.4-1.11.20.70.80.90.70.9-0.20.8-0.5-0.2-0.10.2
Total resting periods, locomotor time 10.40.41.21.1-0.80.80.70.40.60.81.00.11.0-0.20.10.1-0.0
Rest time, locomotor task time 10.70.92.8-1.41.7-1.3-1.5-0.9-0.8-1.0-0.90.2-0.7-0.0-0.3-0.60.5
Distance moved, locomotor task time 10.71.01.80.6-0.50.41.3-0.5-0.61.31.21.00.91.11.21.3-1.2
Vertical activity count, locomotor time 10.10.21.0-1.00.8-0.8-0.5-0.2-0.6-0.4-0.40.0-0.10.20.1-0.0-0.1
Time >=10cm from walls, locomotor time 20.00.10.2-0.10.1-0.20.0-0.3-0.30.30.30.40.50.20.30.2-0.2
Bouts of movement, locomotor time 20.30.41.20.9-1.11.00.90.40.40.70.80.10.80.10.30.4-0.3
Total resting periods, locomotor time 20.20.40.80.6-0.80.60.80.00.00.80.90.30.90.30.50.5-0.5
Rest time, locomotor task time 20.81.03.5-1.91.7-1.5-1.3-1.0-1.2-0.8-0.70.4-0.50.40.1-0.2-0.0
Distance moved, locomotor task time 20.40.51.91.4-1.01.10.70.91.00.40.4-0.40.0-0.5-0.3-0.20.3
Vertical activity count, locomotor time 21.31.82.90.1-0.10.3-1.01.51.3-1.5-1.5-1.7-1.4-1.6-1.6-1.61.6
Light reinforcement 10.10.10.8-0.50.9-0.1-0.4-0.2-0.1-0.4-0.4-0.1-0.4-0.0-0.1-0.20.2
Light reinforcement 20.40.52.3-1.11.5-1.0-1.0-1.0-0.8-0.3-0.30.60.00.20.1-0.20.1
Bone: marrow area1.63.46.9-1.51.9-1.80.3-2.6-2.51.01.22.21.42.32.01.8-1.9
Bone: maximum diameter0.10.10.30.5-0.0-0.50.1-0.5-0.10.40.50.50.30.10.20.1-0.0
Bone: maximum force1.73.16.92.6-2.12.12.6-0.00.52.22.21.01.70.71.31.5-1.3
Bone: maximum moment1.62.86.32.5-2.12.02.5-0.00.52.12.11.01.60.71.21.4-1.2
Mean time between licks in bursts0.10.31.00.4-0.41.00.20.60.7-0.5-0.4-0.7-0.6-0.5-0.5-0.30.4
Mean num. licks in bursts0.10.10.3-0.50.4-0.5-0.10.0-0.4-0.2-0.10.00.00.30.20.2-0.3
Cd content in liver0.70.71.8-1.21.4-1.4-0.7-1.2-1.20.20.10.90.60.70.50.3-0.4
Co content in liver2.93.46.4-1.41.3-0.4-2.31.00.7-2.5-2.5-1.8-2.5-1.6-2.0-2.11.9
Cu content in liver0.20.20.40.20.20.10.5-0.4-0.40.50.50.50.20.60.60.6-0.6
Fe content in liver0.30.40.70.5-0.40.7-0.10.80.8-0.5-0.5-0.8-0.4-0.7-0.7-0.60.6
K content in liver0.40.41.10.7-0.70.81.00.00.10.70.70.30.50.40.50.7-0.6
Mg content in liver0.40.40.8-0.60.6-0.10.2-0.9-0.80.30.10.70.40.80.70.6-0.7
Mn content in liver1.61.75.72.3-2.41.91.51.01.21.41.3-0.11.0-0.40.10.3-0.1
Na content in liver0.60.71.30.70.00.5-0.60.81.0-0.8-0.6-0.9-0.7-1.1-1.0-1.01.1
Rb content in liver0.80.92.2-1.51.3-0.9-0.3-1.3-1.5-0.1-0.10.90.31.10.90.7-0.9
Se content in liver0.30.30.6-0.20.2-0.60.1-0.8-0.70.50.50.80.70.60.60.5-0.5
Sr content in liver1.41.22.91.5-1.71.10.31.61.7-0.0-0.0-1.1-0.3-1.3-1.0-0.80.9
Zn content in liver0.10.10.30.6-0.50.30.50.50.40.20.1-0.3-0.2-0.1-0.00.1-0.1
Bone: minimum diameter2.54.57.7-1.01.3-1.31.0-2.8-2.61.81.92.72.12.62.52.3-2.4
Time in familiar zone, hab. session 10.60.61.2-0.40.4-0.50.2-1.1-0.90.90.71.10.70.90.90.7-0.8
Time in novel zone, hab. session 10.70.71.6-0.50.4-0.1-0.90.60.4-1.3-1.2-1.0-1.2-0.8-0.9-0.90.9
Total zone transitions, hab. session 10.30.41.41.2-1.10.91.00.20.40.80.60.10.40.10.30.4-0.3
Total locomotion distance, hab. session 10.20.30.7-0.70.9-0.8-0.2-0.8-0.80.20.10.60.30.60.50.3-0.4
Locomotion velocity, hab. session 10.10.10.2-0.20.3-0.30.2-0.4-0.30.30.20.40.30.40.40.3-0.3
Time in familiar zone, hab. session 20.40.50.90.0-0.20.5-0.40.90.7-0.7-0.7-0.9-0.7-0.8-0.8-0.70.7
Time in novel zone, hab. session 20.60.61.00.10.1-0.10.8-0.8-0.70.90.81.00.80.91.01.0-1.0
Total zone transitions, hab. session 23.74.78.41.2-0.91.62.9-1.3-1.02.72.62.12.62.22.52.7-2.6
Total locomotion distance, hab. session 21.52.03.2-0.20.60.31.3-1.4-1.31.51.41.71.61.81.81.8-1.8
Locomotion velocity, hab. session 21.72.23.4-0.40.80.11.2-1.6-1.51.51.51.81.71.81.81.8-1.8
Novel to familiar place preference ratio0.80.82.11.0-0.90.31.1-0.3-0.11.41.40.81.30.50.80.8-0.7
Novelty place preference0.70.71.80.6-0.4-0.00.9-0.5-0.41.31.30.91.30.70.90.9-0.8
Time in novel zone, NPP test0.60.61.40.5-0.4-0.10.8-0.5-0.41.21.10.81.20.70.80.8-0.8
Total zone transitions, NPP test1.01.54.11.8-1.41.82.00.10.41.41.20.60.90.60.91.2-1.0
Total locomotion distance, NPP test0.20.20.40.10.30.30.6-0.5-0.40.40.30.50.20.60.60.7-0.6
Locomotion velocity, NPP test0.10.20.40.20.20.30.6-0.4-0.30.50.30.50.30.50.60.6-0.6
Intraocular pressure0.50.72.5-1.30.5-1.3-1.6-0.0-0.1-0.6-0.7-0.3-0.5-0.6-0.8-1.00.9
Delta distance traveled before/after self-admin0.30.40.6-0.30.1-0.1-0.60.60.4-0.7-0.8-0.7-0.8-0.6-0.7-0.70.7
Delta ambulatory time before/after self-admin0.30.40.6-0.1-0.10.4-0.50.60.5-0.7-0.7-0.7-0.8-0.6-0.7-0.70.7
Parametrial fat weight1.63.710.9-3.32.9-3.2-1.6-2.4-2.6-0.8-0.71.3-0.01.40.90.5-0.8
Pavlov. Cond. lever latency0.10.10.5-0.50.7-0.6-0.6-0.3-0.2-0.3-0.30.0-0.3-0.1-0.2-0.30.2
Pavlov. Cond. magazine entry latency0.91.22.30.4-0.50.01.1-1.0-0.81.51.41.31.21.11.31.3-1.2
Pavlov. Cond. change in total contacts0.60.61.40.3-0.3-0.40.6-0.8-0.61.21.11.01.00.70.80.7-0.7
Pavlov. Cond. index score0.10.10.30.4-0.50.10.4-0.10.00.60.50.30.30.10.20.2-0.2
Pavlov. Cond. latency score0.10.10.30.2-0.40.10.4-0.2-0.10.50.50.40.40.30.40.4-0.3
Pavlov. Cond. lever contacts0.10.10.20.2-0.40.20.4-0.0-0.10.30.20.20.20.30.30.4-0.3
Pavlov. Cond. magazine entry number0.10.10.6-0.60.7-0.1-0.20.0-0.2-0.5-0.4-0.2-0.20.1-0.0-0.0-0.0
Pavlov. Cond. intertrial magazine entries0.20.20.6-0.30.7-0.6-0.70.10.0-0.6-0.5-0.4-0.4-0.4-0.5-0.60.5
Pavlov. Cond. lever-magazine prob. diff.0.20.20.60.6-0.70.10.6-0.20.00.80.60.40.40.20.40.4-0.3
Pavlov. Cond. response bias0.10.10.40.5-0.70.10.20.00.20.30.20.10.0-0.1-0.0-0.00.1
Pavlov. Cond. lever latency0.20.21.1-1.10.9-0.7-0.5-0.3-0.6-0.2-0.20.10.30.30.10.1-0.2
Pavlov. Cond. magazine entry latency2.73.37.12.6-2.62.52.70.40.82.32.40.81.60.51.11.4-1.2
Pavlov. Cond. change in total contacts1.21.94.41.8-1.51.21.8-0.50.02.02.11.21.40.71.11.2-1.1
Pavlov. Cond. index score1.31.84.62.1-1.91.71.90.10.61.71.80.61.00.30.81.0-0.8
Pavlov. Cond. latency score1.11.54.02.0-1.81.51.70.20.61.51.60.50.90.20.60.8-0.6
Pavlov. Cond. lever contacts0.20.31.11.1-0.90.80.60.20.40.50.50.10.0-0.10.00.1-0.0
Pavlov. Cond. magazine entry number3.54.411.3-3.43.1-2.9-3.0-0.7-1.2-2.5-2.6-0.6-1.8-0.3-1.0-1.41.1
Pavlov. Cond. intertrial magazine entries0.40.72.6-1.51.6-1.2-1.1-0.7-0.8-0.5-0.50.2-0.20.2-0.1-0.30.2
Pavlov. Cond. lever-magazine prob. diff.1.62.15.52.3-2.11.92.10.20.71.92.00.61.10.30.81.0-0.8
Pavlov. Cond. response bias1.01.43.71.9-1.81.61.70.20.51.51.50.50.80.30.70.9-0.7
Time in closed arm before self-admin0.70.92.3-0.60.8-0.60.1-1.5-1.20.80.81.40.91.11.00.9-0.9
Time in closed arm after self-admin0.10.10.3-0.40.2-0.6-0.1-0.3-0.3-0.0-0.10.20.00.20.20.1-0.2
Time in open arm before self-admin0.91.02.4-0.30.50.2-0.61.00.6-1.5-1.5-1.3-1.5-0.8-1.0-0.90.8
Time in open arm after self-admin0.20.20.40.1-0.30.5-0.10.70.5-0.4-0.3-0.6-0.4-0.5-0.5-0.40.4
Bone: periosteal estimation0.20.51.0-0.00.4-0.70.4-1.0-0.70.60.70.90.60.80.80.7-0.7
Bone: periosteal perimeter0.61.11.90.40.2-0.10.9-1.2-0.81.41.41.41.11.11.21.1-1.1
Bone: post-yield work8.312.120.50.9-0.4-0.23.4-3.2-2.74.34.44.14.53.84.14.1-4.0
Progressive ratio test 1 active lever presses0.20.30.7-0.10.2-0.90.3-0.6-0.60.50.50.60.50.60.60.5-0.6
Progressive ratio test 1 breakpoint0.20.30.7-0.10.1-0.80.3-0.6-0.60.50.50.60.50.60.60.5-0.6
Progressive ratio test 1 inactive lever presses0.10.10.3-0.1-0.0-0.00.1-0.5-0.40.40.40.50.50.40.40.3-0.3
Progressive ratio test 2 active lever presses1.21.53.6-1.31.3-1.7-0.4-1.9-1.80.40.41.50.71.31.10.8-0.9
Progressive ratio test 2 breakpoint1.11.33.2-1.31.3-1.7-0.5-1.8-1.70.40.41.40.71.21.00.7-0.8
Progressive ratio test 2 inactive lever presses2.84.510.9-3.02.8-3.3-1.5-3.2-3.1-0.1-0.12.10.61.91.40.9-1.2
Incentive Sensitization - Responses0.70.91.50.1-0.10.20.8-1.1-0.81.21.21.21.21.11.11.1-1.1
Incentive Sensitization - Breakpoint0.70.91.6-0.10.1-0.00.6-1.2-0.91.11.11.31.11.11.11.0-1.0
Sum of active levers in priming session hrs 5-62.01.83.81.2-1.10.6-0.81.71.9-0.3-0.3-1.3-0.9-2.0-1.7-1.71.8
Progressive ratio2.43.86.41.3-1.20.42.5-1.2-1.02.42.41.92.42.02.22.4-2.3
Food seeking constrained by brief footshock0.20.21.60.6-0.51.30.30.50.5-0.0-0.1-0.3-0.2-0.3-0.2-0.10.1
Seeking ratio, punishment vs. effort2.02.95.3-1.41.5-0.0-2.20.90.7-2.3-2.2-1.6-2.2-1.5-1.8-1.91.8
Retroperitoneal fat weight4.016.949.5-7.07.0-6.8-4.5-4.7-5.0-2.7-2.62.0-1.22.10.9-0.1-0.5
Reaction time number correct0.30.71.20.4-0.50.5-0.50.81.1-0.6-0.6-0.9-0.9-1.1-1.0-1.01.0
Reaction time mean minus median0.81.95.42.3-2.21.91.81.11.21.71.6-0.01.2-0.20.20.5-0.3
Reaction time mean minus median AUC0.41.12.81.7-1.51.60.81.41.50.70.5-0.70.3-0.9-0.6-0.40.5
Reaction time num false alarms0.91.22.5-0.40.4-0.1-1.10.90.7-1.6-1.6-1.3-1.5-1.1-1.2-1.21.2
Reaction time num false alarms AUC0.71.11.80.3-0.30.7-0.51.31.1-1.2-1.2-1.4-1.3-1.1-1.2-1.11.1
Reaction time trials correct on left0.30.71.20.4-0.50.5-0.50.81.1-0.6-0.6-0.9-0.9-1.1-1.0-1.01.0
Reaction time trials on left0.40.81.50.5-0.60.6-0.51.01.2-0.7-0.6-1.0-0.9-1.2-1.1-1.11.1
Reaction time mean0.00.10.30.2-0.10.10.3-0.0-0.10.50.40.20.40.10.20.2-0.2
Reaction time mean AUC0.10.10.40.2-0.0-0.10.3-0.3-0.20.60.60.40.60.30.40.4-0.3
Median of all reaction times0.10.20.4-0.40.4-0.4-0.0-0.5-0.60.30.30.50.30.50.40.3-0.4
Reaction time omissions0.91.33.91.7-2.01.81.11.51.40.80.7-0.70.3-0.7-0.3-0.10.2
Reaction time false alarm rate0.30.40.9-0.20.20.2-0.50.70.4-0.9-0.9-0.8-0.9-0.5-0.7-0.70.6
Reaction time premature initiation rate1.31.87.02.0-1.32.61.01.91.8-0.4-0.4-1.4-0.5-1.0-0.8-0.40.6
Reaction time premature initiations1.83.28.72.4-1.83.00.82.52.6-0.7-0.6-2.0-1.0-1.8-1.5-1.11.3
Std. dev. reaction times0.30.61.41.2-1.21.10.90.60.61.00.9-0.00.6-0.10.10.2-0.2
Reaction time trials completed0.40.81.50.5-0.60.6-0.51.01.2-0.7-0.6-1.0-0.9-1.2-1.1-1.11.1
Reaction time trials AUC0.30.71.20.4-0.40.5-0.50.81.0-0.7-0.7-0.9-0.9-1.1-1.0-1.01.0
Run reversals in cocaine runway, females0.50.51.40.4-0.41.11.2-0.0-0.00.70.60.40.50.60.70.9-0.9
Run reversals in cocaine runway, males2.72.74.3-0.50.30.2-1.81.51.2-1.9-1.9-1.9-2.1-1.9-2.0-2.12.0
Latency to leave start box in cocaine runway1.01.21.90.00.0-0.40.9-1.3-1.11.11.01.31.41.31.31.3-1.3
Latency to leave start box in cocaine runway, F0.50.61.00.10.0-0.20.7-1.0-0.80.60.60.90.91.01.01.0-1.0
Latency to leave start box in cocaine runway, M0.30.30.70.2-0.30.10.5-0.3-0.20.80.80.60.70.40.50.5-0.5
Std. dev. time between licks in bursts1.01.43.0-0.30.00.4-0.81.11.0-1.6-1.6-1.5-1.7-1.1-1.3-1.21.1
Total sessions with >9 infusions1.01.22.00.3-0.3-0.51.2-1.0-0.91.31.31.21.21.31.41.4-1.4
Short access day 1 total inactive lever presses0.81.13.0-1.71.4-1.7-1.0-1.4-1.4-0.6-0.60.7-0.10.70.40.2-0.3
Short access day 10 total inactive lever presses0.00.10.5-0.70.30.2-0.4-0.0-0.2-0.2-0.2-0.0-0.10.0-0.1-0.20.1
Short access day 1 total infusions1.41.84.3-1.31.0-2.10.1-2.0-1.90.40.41.50.81.61.41.2-1.3
Short access day 10 total infusions3.64.67.2-0.1-0.0-1.21.8-2.3-2.22.22.22.52.42.62.72.7-2.7
Short access total infusions1.51.93.0-0.30.2-1.11.1-1.6-1.51.21.21.61.31.71.71.7-1.7
Short access day 1 locomotion1.21.53.0-1.00.9-1.60.2-1.7-1.60.70.71.51.01.41.31.1-1.2
Short access day 10 total locomotion0.91.73.6-0.90.8-1.10.3-1.9-1.71.01.01.71.21.61.51.3-1.4
Short access total locomotion1.51.83.8-1.01.0-1.40.2-2.0-1.80.90.91.71.11.61.51.3-1.4
One hour access (0.3 mA shock)2.42.87.6-2.62.5-2.8-1.4-2.2-2.3-0.3-0.31.40.21.30.90.5-0.7
Compulsive drug intake2.53.06.41.4-1.12.40.02.52.3-1.2-1.2-2.2-1.7-1.8-1.7-1.41.5
One hour access (shock baseline)2.94.413.2-2.92.7-3.6-1.4-3.1-3.00.20.22.20.91.81.40.9-1.1
Social response proportion0.60.71.80.8-0.61.01.00.00.11.31.30.61.20.40.70.7-0.6
Social responses0.10.20.80.6-0.50.90.30.60.60.10.1-0.3-0.0-0.3-0.3-0.20.2
Social time0.20.30.80.7-0.60.80.10.90.8-0.0-0.2-0.6-0.5-0.6-0.5-0.40.4
Soleus weight1.95.615.5-3.93.8-3.6-3.3-1.5-1.8-2.5-2.6-0.1-1.70.1-0.7-1.20.8
Bone: stiffness1.93.16.22.1-1.71.52.5-0.5-0.12.42.41.42.01.21.61.8-1.6
Tibialis anterior weight4.816.440.56.4-6.35.72.65.45.80.40.2-3.6-1.2-3.8-2.7-1.92.4
Time to tail flick, vehicle, before self-admin0.40.40.70.4-0.50.50.8-0.3-0.20.80.70.60.70.60.70.7-0.7
Time to tail flick, vehicle, after self-admin0.91.22.90.6-0.80.51.7-0.4-0.51.41.20.91.21.21.31.5-1.4
Time to tail flick, test, before self-admin1.51.63.3-1.31.5-0.80.2-1.8-1.80.40.41.40.61.71.41.3-1.4
Time to tail flick, test, after self-admin0.00.00.20.0-0.2-0.40.0-0.1-0.00.40.30.20.3-0.00.10.00.0
Delta time to tail flick, vehicle, before/after SA0.60.51.20.5-0.60.71.1-0.1-0.11.00.90.50.80.60.70.8-0.8
Delta time to tail flick, test, before/after SA2.62.75.11.1-1.50.5-0.82.22.2-0.8-0.8-1.9-1.1-2.3-2.0-1.92.0
Tibia length0.41.13.51.9-1.40.40.31.31.6-0.00.1-1.0-0.1-1.3-0.9-0.81.0
Ambulatory time before self-admin0.71.12.30.7-0.60.31.1-0.7-0.51.51.51.21.50.91.11.1-1.1
Ambulatory time after self-admin0.91.02.1-0.40.3-0.70.4-1.3-1.21.11.01.41.11.21.21.0-1.1
Bone: tissue strength0.20.20.40.1-0.2-0.20.4-0.6-0.40.50.40.70.60.50.60.5-0.5
Total heroin consumption1.72.06.32.5-2.12.11.71.71.71.21.3-0.60.7-0.6-0.20.20.1
Bone: trabecular number2.44.07.01.3-1.30.22.5-1.3-1.02.62.62.02.32.02.32.4-2.3
Bone: trabecular spacing0.60.71.5-0.90.8-0.0-1.10.50.2-1.2-1.2-0.8-1.2-0.6-0.9-0.90.8
Bone: trabecular thickness1.62.03.4-0.40.4-1.20.8-1.8-1.61.41.41.81.41.71.71.6-1.6
Bone: trabecular tissue density2.13.18.3-2.62.5-2.9-2.7-0.9-1.0-1.8-1.8-0.2-1.6-0.4-0.9-1.31.1
Water consumed over 24 hours0.30.51.91.2-0.91.40.90.60.70.30.4-0.30.3-0.20.00.2-0.1
Number of responses in last shaping day0.20.20.5-0.2-0.20.3-0.20.60.3-0.4-0.4-0.5-0.7-0.4-0.4-0.40.3