Hub : Genes

Rsl24d1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Rsl24d1 0.25 0.11 0.0e+00 0.24 0.23 0.24 0.24 2.0e-26 2.8e-25 5.1e-26 5.4e-27
2 RMTg gene expression Rsl24d1 0.11 0.07 9.2e-03 0.1 0.06 0.06 0.06 1.2e-03 9.1e-03 8.3e-03 1.3e-02
3 NAcc gene expression Rsl24d1 0.02 0.01 5.8e-03 0.01 0.01 0.01 0.01 2.0e-03 1.8e-03 1.9e-03 2.3e-03
4 pVTA gene expression Rsl24d1 0.07 0.04 1.3e-06 0.08 0.06 0.06 0.06 8.4e-07 5.7e-06 2.5e-05 6.5e-06
5 Brain gene expression Rsl24d1 0.17 0.07 3.9e-16 0.18 0.18 0.19 0.19 5.8e-17 8.0e-17 3.0e-17 1.5e-17
6 Liver gene expression Rsl24d1 0.08 0.04 1.2e-10 0.07 0.07 0.07 0.07 1.2e-08 2.4e-08 4.7e-08 2.0e-08
7 Eye gene expression Rsl24d1 0.52 0.16 5.6e-04 0.08 0.08 0.01 0.09 2.3e-02 2.5e-02 2.2e-01 1.6e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density0.10.20.50.50.70.40.20.30.60.3
Area under the delay curve0.20.21.3-0.20.2-0.1-0.30.1-0.21.1
BMI with tail6.923.932.2-5.2-4.7-5.5-5.7-5.0-5.2-2.1
BMI without tail2.47.412.9-2.4-2.4-2.9-3.6-3.2-2.5-1.6
Body weight3.214.221.1-4.6-3.8-4.3-4.2-3.5-3.7-1.2
Weight adjusted by age4.06.07.9-2.6-2.8-2.5-2.5-2.5-2.0-2.1
Bone surface0.20.40.6-0.4-0.3-0.5-0.7-0.8-0.6-0.8
Bone volume0.20.30.6-0.6-0.4-0.6-0.7-0.7-0.4-0.5
Breakpoint value in progressive ratio session0.10.10.20.30.1-0.2-0.2-0.2-0.4-0.1
Number of licking bursts1.42.34.42.11.41.91.41.11.70.6
Context. condit. distance diff. score0.20.20.8-0.0-0.10.20.50.50.50.9
Locomotion velocity, session 11.21.22.2-1.0-0.6-1.1-1.2-1.3-0.9-1.5
Locomotion distance, session 10.20.20.60.80.70.50.20.10.5-0.1
Locomotion velocity, session 20.10.10.20.20.5-0.1-0.4-0.2-0.4-0.2
Locomotion distance, session 20.30.51.10.30.2-0.4-1.0-0.8-0.9-0.6
Locomotion velocity, session 30.20.20.80.70.40.1-0.2-0.4-0.2-0.9
Locomotion distance, session 32.42.64.22.02.01.81.51.31.40.8
Stereotopy head waving bouts, day 30.70.82.0-1.2-1.4-1.0-0.4-0.6-0.7-0.6
Stereotopy head waving duration, day 31.41.63.2-1.7-1.8-1.5-0.9-1.0-0.8-0.9
Locomotion velocity, session 70.50.61.11.00.81.00.60.70.50.6
Locomotion distance, session 71.01.22.61.61.51.30.70.80.80.4
Stereotopy head waving bouts, day 70.91.01.4-0.8-0.8-1.1-1.0-1.1-0.9-1.2
Stereotopy head waving duration, day 71.21.43.0-0.8-0.9-1.1-1.1-1.4-1.1-1.7
Locomotion velocity, session 80.60.71.6-0.0-0.3-0.6-0.9-1.0-1.0-1.3
Locomotion distance, session 80.20.31.21.10.90.6-0.00.20.00.3
Degree of sensitization distance0.00.00.00.20.20.1-0.00.10.1-0.0
Degree of sensitization stereotypy0.70.81.4-0.7-0.6-0.9-0.9-1.0-0.7-1.2
Conditioned locomotion0.40.52.7-0.6-0.4-0.3-0.30.30.31.6
Cocaine response after cond. corrected4.35.27.1-2.7-2.6-2.5-1.9-2.1-2.1-1.9
Cocaine response after cond. not corrected3.13.65.8-2.3-2.4-2.1-1.5-1.7-1.6-1.4
Cocaine response before conditioning0.91.02.01.10.91.00.90.90.81.4
Saline control response0.10.10.4-0.1-0.3-0.20.0-0.20.3-0.6
Bone: connectivity density1.11.73.21.81.81.40.90.81.30.2
Bone: cortical apparent density1.01.32.31.20.91.31.11.01.51.0
Bone: cortical area0.50.82.7-1.7-1.3-0.7-0.00.10.60.3
Bone: cortical porosity1.31.42.60.70.91.01.51.61.21.2
Bone: cortical porosity1.61.73.00.91.01.11.61.71.11.5
Bone: cortical thickness1.01.64.5-0.00.30.81.41.52.11.3
Bone: cortical thickness0.30.30.8-0.1-0.20.30.60.70.90.6
Bone: cortical tissue density1.01.32.21.21.01.31.11.01.51.0
Condit. Reinf. active minus inactive responses0.91.02.11.31.20.90.50.9-0.11.5
Condit. Reinf. active-inactive response ratio0.80.92.90.50.30.80.91.20.11.7
Condit. Reinf. active responses0.40.51.91.41.20.4-0.2-0.0-0.50.2
Condit. Reinf. inactive responses0.91.02.91.11.0-0.2-0.9-1.1-0.4-1.7
Incentive salience index mean0.60.82.11.11.00.60.30.7-0.41.4
Condit. Reinf. lever presses0.30.41.10.90.70.30.20.6-0.41.1
Condit. Reinf. active minus inactive responses1.82.32.8-1.4-1.5-1.7-1.7-1.6-1.2-1.5
Condit. Reinf. active-inactive response ratio1.41.72.9-1.7-1.6-1.5-1.1-1.0-0.8-1.1
Condit. Reinf. active responses0.81.21.9-1.0-1.0-1.3-1.4-1.2-0.8-0.7
Condit. Reinf. inactive responses0.40.51.11.01.00.60.20.20.60.7
Condit. Reinf. lever presses0.50.61.80.00.10.51.00.91.30.8
Condit. Reinf. lever reinforcers received0.50.81.3-0.9-0.9-1.1-1.1-1.0-0.5-0.4
Conditioned reinforcement - actives0.20.30.8-0.3-0.8-0.3-0.5-0.4-0.9-0.5
Conditioned reinforcement - inactives0.10.10.4-0.6-0.4-0.3-0.3-0.20.2-0.4
Conditioned locomotion0.10.10.50.1-0.00.40.30.5-0.00.7
Patch foraging indifference point 0 sec0.10.20.3-0.4-0.4-0.4-0.5-0.6-0.5-0.6
Patch foraging indifference point AUC0.91.33.41.81.81.20.40.60.00.7
Delay disc. indifference point, 0s delay1.21.43.21.41.81.20.40.80.51.4
Delay disc. indifference point, 16s delay0.60.63.0-0.20.20.20.40.80.61.7
Delay disc. indifference point, 2s delay0.00.00.10.20.20.30.10.10.20.3
Delay disc. indifference point, 24s delay0.30.31.00.20.50.30.40.50.81.0
Delay disc. indifference point, 4s delay0.50.51.80.40.80.60.40.70.11.4
Delay disc. indifference point, 8s delay0.40.41.0-0.4-0.2-0.6-0.9-0.6-1.00.4
Indifference point function ln k1.52.75.9-2.2-2.4-1.7-1.1-1.2-1.1-1.2
Indifference point function log k1.52.75.9-2.2-2.4-1.7-1.1-1.2-1.1-1.2
Patch foraging total patch changes 0 sec0.20.30.4-0.5-0.4-0.5-0.5-0.6-0.6-0.6
Patch foraging total patch changes 12 sec0.50.61.51.01.20.80.70.50.70.1
Patch foraging total patch changes 18 sec0.10.20.50.30.70.50.40.40.50.4
Patch foraging total patch changes 24 sec0.30.52.00.81.40.50.20.10.2-0.7
Patch foraging total patch changes 6 sec0.30.51.51.01.20.3-0.6-0.5-0.5-0.3
Patch foraging time to switch 0 sec0.40.91.40.80.70.90.90.91.21.0
Patch foraging water rate 0 sec1.22.43.2-1.8-1.6-1.6-1.4-1.3-1.8-1.4
Patch foraging water rate 12 sec2.24.67.6-2.4-1.7-2.4-1.7-2.1-1.7-2.7
Patch foraging water rate 18 sec0.30.41.1-1.0-0.5-0.7-0.2-0.3-0.0-0.9
Patch foraging water rate 24 sec0.20.31.20.40.40.20.60.10.4-1.1
Patch foraging water rate 6 sec0.40.61.7-0.9-0.6-0.7-0.4-0.5-0.8-1.3
Seeking ratio, delayed vs. immediate footshock2.02.56.2-0.9-1.6-1.3-1.6-1.4-2.5-1.3
Distance traveled before self-admin0.10.10.70.1-0.10.10.10.1-0.8-0.3
Distance traveled after self-admin2.02.53.3-1.6-1.6-1.5-1.1-1.3-1.8-1.8
Extensor digitorum longus weight7.730.336.0-5.5-5.3-5.9-6.0-5.5-6.0-4.1
Bone: elastic displacement0.00.00.1-0.2-0.0-0.2-0.3-0.2-0.20.1
Bone: elastic work0.10.10.4-0.2-0.20.00.00.20.10.7
Bone: endosteal estimation2.55.57.9-2.4-2.6-2.4-2.3-2.2-2.8-1.6
Bone: endosteal perimeter2.96.39.3-3.0-2.8-2.9-2.6-2.3-2.4-1.0
Epididymis fat weight0.00.10.50.40.70.2-0.1-0.10.1-0.2
Delta time in closed arm before/after self-admin0.50.51.00.50.10.50.70.81.01.0
Delta time in open arm before/after self-admin0.40.41.00.50.50.60.70.41.0-0.7
Diff in mean of infusions in LGA sessions1.21.54.1-0.5-1.1-1.2-1.5-1.1-2.0-0.1
Delay discount exponential model param0.10.20.90.3-0.10.10.3-0.00.2-1.0
Extinction: sum of active levers before priming0.10.10.50.00.10.00.1-0.00.5-0.7
Active lever presses in extinction session 60.80.81.3-0.3-0.8-0.9-0.8-0.9-1.2-1.2
Bone: final force0.50.81.8-1.4-1.2-1.0-0.6-0.5-0.6-0.1
Bone: final moment0.30.51.6-1.3-1.1-0.8-0.3-0.2-0.30.2
Food consumed during 24 hour testing period0.91.22.6-1.3-1.6-1.0-0.7-0.8-0.8-1.1
Glucose0.71.02.0-0.4-0.9-0.8-1.1-1.2-1.1-1.4
Heart weight0.30.40.8-0.70.1-0.9-0.8-0.7-0.7-0.2
Delay discount hyperbolic model param0.20.21.20.2-0.2-0.00.1-0.20.2-1.1
Intermittent access intake day 1-15 change0.20.41.3-0.2-0.6-0.5-0.5-0.7-0.2-1.1
Intermittent access intake escalation0.20.51.2-0.5-0.7-0.7-0.6-0.8-0.2-1.1
Intermittent access intake escalation 20.60.71.0-0.9-1.0-0.9-0.8-0.8-0.8-0.7
Intermitt. access day 1 inactive lever presses0.20.62.10.20.10.50.60.71.50.9
Intermitt. access day 15 inactive lever presses0.10.31.0-1.0-0.0-0.6-0.0-0.10.8-0.2
Intermitt. access escalation Index0.30.40.9-0.80.5-0.10.10.4-1.00.9
Intermittent access day 1 total infusions0.81.33.01.10.61.31.71.40.90.5
Intermittent access day 15 total infusions0.30.41.20.70.20.71.10.70.5-0.0
Intermittent access terminal intake (last 3 days)0.10.20.60.4-0.20.40.80.6-0.10.2
Intermittent access total infusions0.40.41.40.50.10.71.20.80.5-0.1
Intermittent access day 1 locomotion1.01.22.41.20.41.51.51.20.70.5
Intermittent access day 15 total locomotion0.20.41.40.0-0.20.71.21.00.30.3
Intermittent access total locomotion0.10.10.4-0.3-0.60.00.20.0-0.3-0.5
Intermittent access standard deviation0.00.10.3-0.3-0.6-0.10.20.00.1-0.4
Left kidney weight1.78.112.0-3.5-3.1-3.3-2.9-2.8-1.8-2.3
Right kidney weight1.56.78.6-2.7-2.3-2.9-2.8-2.8-1.9-2.5
Cocaine induced anxiety0.30.41.90.30.10.40.40.70.31.4
Post-drug Anxiety1.82.03.82.01.11.61.41.40.91.1
Baseline Anxiety0.91.03.11.81.01.20.70.20.4-0.9
Tail length0.41.42.91.51.21.40.90.81.7-0.2
Length with tail0.00.10.4-0.7-0.3-0.3-0.2-0.20.1-0.6
Length without tail1.75.512.1-3.5-2.5-2.7-1.9-1.6-2.6-0.7
Times rat made contact with spout0.20.30.9-0.00.20.30.60.40.90.4
Lifetime Intake0.30.31.00.40.20.61.00.70.3-0.3
Liver weight, left2.84.66.3-2.0-2.0-2.3-2.5-2.4-1.8-1.8
Liver weight, right2.23.86.4-1.4-2.0-1.9-2.5-2.3-1.4-1.8
Locomotor activity4.46.811.1-3.3-2.8-2.9-2.7-2.3-2.3-1.7
Locomotor testing distance3.15.58.6-2.9-2.5-2.6-2.3-2.2-1.9-1.9
Locomotor testing rearing0.91.82.1-1.2-1.4-1.4-1.4-1.4-1.2-1.3
Locomotion in novel chamber0.20.30.4-0.1-0.50.20.60.60.60.6
Locomotion in novel chamber post-restriction0.20.40.60.70.70.50.20.30.70.8
Fecal boli incidents, locomotor time 10.71.02.10.71.10.80.81.10.71.4
Change in fecal boli incidents, locomotor task1.71.73.4-1.5-1.8-1.1-0.6-0.8-1.2-1.5
Time >=10cm from walls, locomotor time 10.60.71.2-0.8-1.1-0.8-1.0-0.7-0.80.0
Bouts of movement, locomotor time 10.10.10.4-0.10.0-0.2-0.3-0.1-0.60.7
Total resting periods, locomotor time 10.10.10.4-0.10.0-0.0-0.10.1-0.30.6
Rest time, locomotor task time 10.60.73.6-0.1-0.10.40.40.90.71.9
Distance moved, locomotor task time 10.10.20.70.60.50.20.1-0.3-0.1-0.8
Vertical activity count, locomotor time 10.00.10.30.50.60.30.1-0.1-0.2-0.1
Time >=10cm from walls, locomotor time 20.10.20.9-0.5-0.2-0.1-0.20.2-0.10.9
Bouts of movement, locomotor time 20.40.71.3-0.4-0.2-0.8-1.1-1.1-1.0-0.6
Total resting periods, locomotor time 20.40.71.4-0.4-0.3-0.9-1.2-1.1-0.9-0.7
Rest time, locomotor task time 20.40.51.20.40.00.60.60.80.91.1
Distance moved, locomotor task time 20.20.30.90.40.2-0.0-0.5-0.7-0.4-0.9
Vertical activity count, locomotor time 20.40.51.21.01.11.00.50.30.60.0
Light reinforcement 11.33.34.9-2.0-1.6-2.0-2.1-1.7-2.2-0.6
Light reinforcement 20.40.61.20.0-0.30.51.11.10.81.0
Bone: marrow area2.65.77.9-2.5-2.7-2.5-2.3-2.2-2.8-1.6
Bone: maximum diameter2.44.59.8-3.1-2.6-2.4-1.8-1.7-1.4-0.9
Bone: maximum force0.50.92.0-1.4-1.2-1.1-0.8-0.6-0.8-0.2
Bone: maximum moment0.40.71.9-1.4-1.2-0.9-0.5-0.3-0.50.1
Mean time between licks in bursts0.30.71.10.80.61.01.00.90.90.6
Mean num. licks in bursts1.21.84.8-2.2-1.4-1.7-0.9-0.9-1.1-0.4
Cd content in liver1.92.16.01.32.41.41.11.11.01.3
Co content in liver2.12.46.10.91.51.21.31.71.32.5
Cu content in liver0.10.10.1-0.3-0.4-0.3-0.2-0.0-0.40.2
Fe content in liver0.30.41.0-0.2-0.2-0.5-0.7-0.7-0.4-1.0
K content in liver0.50.50.9-0.8-0.4-0.9-0.6-0.6-0.1-1.0
Mg content in liver0.60.70.9-0.7-0.8-0.9-0.9-0.9-0.6-0.8
Mn content in liver0.50.61.6-1.3-1.1-0.60.00.10.80.6
Na content in liver4.14.46.8-1.6-1.8-2.2-2.6-2.4-2.2-1.6
Rb content in liver1.01.22.0-0.8-0.8-1.2-1.1-1.2-1.0-1.4
Se content in liver0.20.20.90.30.30.30.40.21.0-0.6
Sr content in liver1.11.01.41.01.21.00.80.91.00.8
Zn content in liver0.00.00.2-0.20.0-0.10.10.30.10.4
Bone: minimum diameter0.30.61.6-1.2-0.9-0.50.00.40.31.3
Time in familiar zone, hab. session 10.10.10.6-0.10.30.00.30.50.10.8
Time in novel zone, hab. session 10.10.10.20.1-0.00.30.20.10.4-0.2
Total zone transitions, hab. session 10.50.61.91.01.40.70.60.40.70.1
Total locomotion distance, hab. session 10.20.20.80.70.90.30.2-0.10.3-0.5
Locomotion velocity, hab. session 10.10.10.50.30.60.00.0-0.2-0.1-0.7
Time in familiar zone, hab. session 20.20.20.40.50.50.40.50.30.6-0.3
Time in novel zone, hab. session 20.30.30.9-0.8-0.9-0.5-0.4-0.2-0.50.2
Total zone transitions, hab. session 20.10.20.50.60.70.0-0.5-0.2-0.3-0.1
Total locomotion distance, hab. session 20.10.10.30.30.5-0.2-0.5-0.3-0.2-0.0
Locomotion velocity, hab. session 20.10.10.30.30.5-0.1-0.3-0.1-0.10.2
Novel to familiar place preference ratio1.21.32.2-1.2-1.2-1.2-1.2-0.9-1.5-0.1
Novelty place preference1.31.42.4-1.3-1.3-1.3-1.2-0.9-1.6-0.2
Time in novel zone, NPP test1.71.82.6-1.5-1.6-1.5-1.3-1.0-1.6-0.4
Total zone transitions, NPP test0.10.10.40.30.7-0.1-0.4-0.2-0.10.1
Total locomotion distance, NPP test0.20.20.40.10.5-0.3-0.5-0.6-0.3-0.6
Locomotion velocity, NPP test0.20.31.00.61.00.1-0.2-0.20.0-0.5
Intraocular pressure0.10.10.40.40.60.30.20.20.4-0.1
Delta distance traveled before/after self-admin3.23.44.8-1.9-2.2-1.9-1.4-1.7-1.5-2.0
Delta ambulatory time before/after self-admin1.92.33.6-1.9-1.8-1.6-1.0-1.3-1.1-1.7
Parametrial fat weight1.84.26.42.12.42.31.81.72.51.4
Pavlov. Cond. lever latency0.40.51.3-1.0-1.1-0.3-0.1-0.50.5-0.9
Pavlov. Cond. magazine entry latency3.84.811.22.02.51.81.62.31.13.4
Pavlov. Cond. change in total contacts0.91.02.71.01.10.70.51.0-0.21.6
Pavlov. Cond. index score2.73.46.22.12.31.71.21.80.52.5
Pavlov. Cond. latency score2.12.74.82.02.11.41.11.50.52.2
Pavlov. Cond. lever contacts0.80.92.31.21.30.60.30.8-0.31.5
Pavlov. Cond. magazine entry number3.64.59.4-2.1-2.4-1.9-1.6-2.2-1.0-3.1
Pavlov. Cond. intertrial magazine entries0.80.94.20.40.1-0.2-0.8-1.1-0.5-2.1
Pavlov. Cond. lever-magazine prob. diff.2.32.95.62.02.11.51.01.60.22.4
Pavlov. Cond. response bias2.32.97.51.62.01.31.01.70.32.7
Pavlov. Cond. lever latency0.60.81.6-0.5-0.8-0.8-0.7-0.9-1.0-1.3
Pavlov. Cond. magazine entry latency5.46.59.92.02.52.52.72.63.12.2
Pavlov. Cond. change in total contacts1.21.93.51.01.41.31.31.41.91.3
Pavlov. Cond. index score2.12.84.61.21.71.61.71.72.11.6
Pavlov. Cond. latency score1.62.13.80.91.41.31.41.52.01.4
Pavlov. Cond. lever contacts0.60.81.60.60.80.80.70.91.01.2
Pavlov. Cond. magazine entry number4.15.17.4-2.0-2.3-2.3-2.4-2.3-2.7-1.7
Pavlov. Cond. intertrial magazine entries1.11.62.8-0.6-1.1-1.2-1.2-1.4-1.4-1.7
Pavlov. Cond. lever-magazine prob. diff.2.53.35.31.41.81.81.81.82.31.7
Pavlov. Cond. response bias2.53.44.11.51.91.81.71.92.02.0
Time in closed arm before self-admin0.10.10.40.30.50.20.20.4-0.20.7
Time in closed arm after self-admin0.30.30.40.50.50.50.50.50.60.6
Time in open arm before self-admin0.80.81.2-1.1-1.1-1.1-0.9-0.7-0.9-0.4
Time in open arm after self-admin0.30.40.9-0.9-0.8-0.7-0.4-0.4-0.4-0.6
Bone: periosteal estimation1.93.96.8-2.6-2.6-2.1-1.7-1.6-1.7-1.0
Bone: periosteal perimeter2.44.27.1-2.6-2.7-2.3-2.0-1.8-1.4-0.9
Bone: post-yield work0.20.20.5-0.2-0.3-0.5-0.5-0.5-0.7-0.4
Progressive ratio test 1 active lever presses0.20.20.40.50.20.60.60.5-0.0-0.3
Progressive ratio test 1 breakpoint0.20.20.50.50.30.60.70.60.1-0.2
Progressive ratio test 1 inactive lever presses1.21.73.61.30.51.61.91.41.3-0.3
Progressive ratio test 2 active lever presses0.50.61.6-0.8-0.6-0.5-0.2-0.4-1.3-1.0
Progressive ratio test 2 breakpoint0.40.51.3-0.8-0.5-0.5-0.2-0.3-1.1-0.9
Progressive ratio test 2 inactive lever presses0.20.31.0-0.50.10.31.00.80.6-0.0
Incentive Sensitization - Responses0.91.33.1-1.6-0.9-1.2-0.9-0.7-1.8-0.7
Incentive Sensitization - Breakpoint0.91.12.7-1.4-0.7-1.1-0.8-0.7-1.6-0.6
Sum of active levers in priming session hrs 5-60.20.20.5-0.2-0.6-0.3-0.1-0.3-0.7-0.7
Progressive ratio0.50.82.11.10.40.70.60.9-0.21.5
Food seeking constrained by brief footshock0.50.61.3-0.2-0.6-0.5-0.9-0.9-0.6-1.1
Seeking ratio, punishment vs. effort3.14.48.0-2.0-1.6-2.0-2.2-2.4-1.3-2.8
Retroperitoneal fat weight0.52.14.81.22.21.31.20.92.00.6
Reaction time number correct1.12.23.3-1.2-1.3-1.5-1.8-1.8-1.1-1.5
Reaction time mean minus median0.20.40.70.80.50.80.80.50.40.2
Reaction time mean minus median AUC0.41.01.81.30.91.21.41.00.80.1
Reaction time num false alarms0.20.20.40.60.60.50.40.20.5-0.2
Reaction time num false alarms AUC0.10.20.60.30.30.10.1-0.30.4-0.8
Reaction time trials correct on left1.12.23.3-1.2-1.3-1.5-1.8-1.8-1.1-1.5
Reaction time trials on left1.12.23.3-1.2-1.3-1.5-1.8-1.8-1.1-1.5
Reaction time mean2.33.75.22.01.62.12.32.11.71.5
Reaction time mean AUC2.13.34.72.01.62.12.22.01.41.3
Median of all reaction times3.65.26.92.31.92.52.62.52.11.9
Reaction time omissions0.10.20.30.40.60.30.40.10.1-0.6
Reaction time false alarm rate0.70.91.31.01.11.01.20.91.00.3
Reaction time premature initiation rate0.70.91.5-0.5-1.1-1.0-0.9-1.1-0.6-1.2
Reaction time premature initiations1.42.43.1-1.1-1.7-1.6-1.7-1.8-1.2-1.7
Std. dev. reaction times1.22.23.11.51.41.71.81.51.40.9
Reaction time trials completed1.12.23.3-1.2-1.3-1.5-1.8-1.8-1.1-1.5
Reaction time trials AUC1.01.82.8-1.1-1.1-1.4-1.7-1.6-1.0-1.4
Run reversals in cocaine runway, females0.10.10.5-0.1-0.4-0.1-0.1-0.20.7-0.3
Run reversals in cocaine runway, males0.50.51.20.30.4-0.4-0.8-0.8-0.6-1.1
Latency to leave start box in cocaine runway2.02.23.7-1.4-1.4-1.3-1.9-1.7-1.6-1.1
Latency to leave start box in cocaine runway, F0.91.01.8-0.5-0.6-0.6-1.4-1.3-1.0-1.3
Latency to leave start box in cocaine runway, M4.03.76.1-2.5-2.0-2.1-2.2-1.8-1.9-0.5
Std. dev. time between licks in bursts0.00.00.1-0.00.1-0.1-0.4-0.3-0.3-0.2
Total sessions with >9 infusions0.30.41.50.70.00.60.40.1-0.1-1.2
Short access day 1 total inactive lever presses0.20.20.5-0.7-0.5-0.00.20.10.7-0.5
Short access day 10 total inactive lever presses0.20.61.4-0.00.50.71.00.91.20.3
Short access day 1 total infusions0.20.20.7-0.2-0.80.1-0.0-0.2-0.4-0.8
Short access day 10 total infusions1.21.53.11.20.81.51.81.50.80.4
Short access total infusions0.50.71.31.00.51.11.20.80.6-0.4
Short access day 1 locomotion0.10.10.3-0.2-0.4-0.1-0.2-0.2-0.6-0.2
Short access day 10 total locomotion0.10.20.9-0.1-1.00.30.30.10.5-0.5
Short access total locomotion0.10.20.40.2-0.20.60.50.40.5-0.1
One hour access (0.3 mA shock)0.40.41.2-1.1-1.0-0.8-0.3-0.3-0.5-0.2
Compulsive drug intake0.81.01.5-1.0-1.0-1.0-1.2-1.2-0.1-1.0
One hour access (shock baseline)0.30.51.30.10.40.51.11.00.20.7
Social response proportion0.60.71.9-1.1-1.4-0.8-0.6-0.4-0.70.3
Social responses0.10.10.2-0.4-0.3-0.4-0.3-0.3-0.10.1
Social time0.20.30.6-0.7-0.8-0.50.2-0.2-0.6-0.8
Soleus weight16.047.056.5-6.7-6.5-7.2-7.5-7.1-7.4-5.3
Bone: stiffness1.11.92.7-1.2-1.3-1.3-1.3-1.5-1.3-1.6
Tibialis anterior weight14.649.555.5-7.0-7.2-7.4-7.1-7.0-7.5-6.0
Time to tail flick, vehicle, before self-admin0.80.92.91.71.00.90.40.50.70.8
Time to tail flick, vehicle, after self-admin0.10.10.6-0.3-0.8-0.10.0-0.0-0.4-0.2
Time to tail flick, test, before self-admin1.81.94.21.21.31.31.21.50.82.1
Time to tail flick, test, after self-admin2.02.12.51.51.41.61.51.41.61.1
Delta time to tail flick, vehicle, before/after SA0.20.20.5-0.7-0.7-0.10.20.0-0.6-0.4
Delta time to tail flick, test, before/after SA0.20.20.5-0.7-0.6-0.30.1-0.10.1-0.4
Tibia length0.20.71.9-1.0-1.1-0.30.30.6-0.11.4
Ambulatory time before self-admin0.20.30.50.60.50.70.70.6-0.20.2
Ambulatory time after self-admin1.61.93.3-1.5-1.6-1.3-0.6-1.0-1.5-1.8
Bone: tissue strength0.70.71.10.70.50.91.01.00.70.8
Total heroin consumption1.01.22.2-0.1-0.6-1.1-1.3-1.3-1.2-1.5
Bone: trabecular number0.81.32.61.41.61.20.90.91.10.7
Bone: trabecular spacing0.00.00.2-0.1-0.00.1-0.00.00.30.5
Bone: trabecular thickness0.10.20.4-0.7-0.3-0.30.30.20.6-0.1
Bone: trabecular tissue density6.08.815.4-3.9-3.7-3.3-2.4-2.5-2.4-2.1
Water consumed over 24 hours0.30.40.70.30.20.60.70.80.80.7
Number of responses in last shaping day0.20.20.5-0.5-0.7-0.4-0.6-0.40.2-0.2