Hub : Genes

Rsl24d1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Rsl24d1 0.28 0.11 0.0e+00 0.26 0.26 0.25 0.27 8.9e-29 3.9e-28 1.6e-27 1.4e-29
2 Liver gene expression Rsl24d1 0.09 0.05 2.7e-13 0.1 0.09 0.09 0.1 1.5e-11 3.1e-10 2.2e-10 7.1e-11
3 NAcc gene expression Rsl24d1 0.09 0.05 8.5e-08 0.06 0.07 0.07 0.07 2.2e-07 3.4e-08 3.1e-08 2.7e-08
4 pVTA gene expression Rsl24d1 0.07 0.04 5.4e-03 0.04 0.04 0.02 0.04 6.7e-03 1.0e-02 6.1e-02 1.1e-02
5 RMTg gene expression Rsl24d1 0.19 0.11 2.2e-04 0.18 0.15 0.17 0.17 1.1e-05 7.0e-05 3.2e-05 2.8e-05
6 Brain gene expression Rsl24d1 0.22 0.08 0.0e+00 0.26 0.25 0.25 0.26 6.8e-24 5.3e-23 2.3e-23 2.9e-24
7 Eye gene expression Rsl24d1 0.52 0.16 6.8e-04 0.07 0.06 0.02 0.07 3.2e-02 4.8e-02 1.6e-01 3.2e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density0.10.10.30.3-0.30.4-0.3-0.50.50.1
Area under the delay curve0.40.53.0-0.30.2-0.00.00.30.0-1.7
BMI with tail6.019.524.6-4.74.5-4.95.04.9-4.60.2
BMI without tail2.95.99.6-1.51.6-2.42.83.1-3.02.0
Body weight3.012.818.1-4.33.9-3.93.93.7-3.40.3
Weight adjusted by age5.05.77.3-2.52.1-2.52.52.7-2.71.5
Bone surface0.30.50.8-0.70.8-0.70.60.5-0.60.9
Bone volume0.30.40.8-0.80.9-0.70.60.5-0.50.6
Breakpoint value in progressive ratio session0.00.00.10.2-0.1-0.00.20.1-0.0-0.1
Number of licking bursts1.92.33.31.8-1.71.7-1.6-1.51.30.1
Context. condit. distance diff. score0.20.20.40.1-0.20.3-0.4-0.60.5-0.7
Locomotion velocity, session 11.41.62.6-0.91.2-1.21.41.1-1.31.6
Locomotion distance, session 10.10.20.80.9-0.50.4-0.1-0.30.10.1
Locomotion velocity, session 20.10.10.30.2-0.2-0.10.60.3-0.3-0.3
Locomotion distance, session 20.30.51.40.2-0.1-0.51.20.9-0.90.1
Locomotion velocity, session 30.40.41.70.7-0.40.00.60.2-0.51.3
Locomotion distance, session 32.12.34.02.0-2.01.7-1.3-1.41.2-0.5
Stereotopy head waving bouts, day 30.60.81.6-1.11.2-0.80.70.4-0.51.0
Stereotopy head waving duration, day 31.31.63.2-1.61.8-1.21.10.8-0.81.2
Locomotion velocity, session 70.80.91.21.1-1.11.0-0.9-0.90.9-0.7
Locomotion distance, session 71.01.32.91.7-1.61.2-0.8-1.10.8-0.1
Stereotopy head waving bouts, day 71.21.33.1-0.80.9-1.01.30.9-1.11.8
Stereotopy head waving duration, day 71.51.84.4-0.91.0-1.21.31.2-1.32.1
Locomotion velocity, session 80.60.72.0-0.10.3-0.60.90.7-0.91.4
Locomotion distance, session 80.30.41.41.2-1.00.50.0-0.30.2-0.3
Degree of sensitization distance0.00.00.10.2-0.10.1-0.1-0.10.10.3
Degree of sensitization stereotypy1.01.11.9-0.80.8-1.01.31.0-1.11.4
Conditioned locomotion0.50.63.0-0.70.3-0.40.30.4-0.1-1.7
Cocaine response after cond. corrected5.05.78.8-3.02.8-2.52.22.2-2.21.5
Cocaine response after cond. not corrected3.53.86.7-2.62.5-2.11.71.7-1.71.1
Cocaine response before conditioning1.21.52.01.3-1.31.2-1.1-1.01.1-1.4
Saline control response0.20.31.50.00.4-0.0-0.1-0.20.11.2
Bone: connectivity density1.01.63.11.8-1.51.4-1.1-1.21.00.4
Bone: cortical apparent density0.40.60.80.7-0.70.8-0.9-0.80.8-0.6
Bone: cortical area0.71.13.6-1.91.7-0.90.20.3-0.2-0.4
Bone: cortical porosity0.80.91.40.4-0.60.9-1.0-1.11.2-1.2
Bone: cortical porosity1.61.72.40.8-1.11.3-1.4-1.41.5-1.4
Bone: cortical thickness0.50.91.6-0.30.10.6-1.2-1.21.3-1.1
Bone: cortical thickness0.30.41.0-0.00.00.5-1.0-0.60.8-0.5
Bone: cortical tissue density0.50.60.80.8-0.80.9-0.9-0.90.8-0.6
Condit. Reinf. active minus inactive responses1.21.34.31.1-1.40.9-0.5-0.40.7-2.1
Condit. Reinf. active-inactive response ratio1.31.44.50.3-0.60.8-1.2-1.01.3-2.1
Condit. Reinf. active responses0.60.71.81.3-1.30.40.40.4-0.2-0.9
Condit. Reinf. inactive responses1.11.32.11.4-0.9-0.31.31.1-1.21.5
Incentive salience index mean1.01.25.80.9-1.20.6-0.2-0.10.5-2.4
Condit. Reinf. lever presses0.60.94.20.8-1.00.30.10.10.2-2.0
Condit. Reinf. active minus inactive responses2.12.63.1-1.81.7-1.71.81.6-1.71.0
Condit. Reinf. active-inactive response ratio1.92.04.0-2.01.9-1.51.11.0-1.20.9
Condit. Reinf. active responses1.11.52.3-1.31.1-1.31.51.4-1.3-0.1
Condit. Reinf. inactive responses0.50.61.21.0-1.10.6-0.0-0.20.4-1.1
Condit. Reinf. lever presses0.40.50.90.0-0.10.6-0.8-1.01.0-0.9
Condit. Reinf. lever reinforcers received0.71.01.6-1.21.0-1.11.21.1-0.9-0.4
Conditioned reinforcement - actives0.10.10.2-0.10.1-0.20.10.3-0.30.5
Conditioned reinforcement - inactives0.20.20.5-0.50.7-0.40.00.2-0.20.6
Conditioned locomotion0.40.41.6-0.0-0.40.5-0.8-0.50.6-1.3
Patch foraging indifference point 0 sec0.10.20.3-0.40.2-0.30.40.5-0.60.4
Patch foraging indifference point AUC1.01.23.11.8-1.71.0-0.2-0.50.6-0.6
Delay disc. indifference point, 0s delay1.11.22.31.2-1.41.1-0.7-0.50.8-1.5
Delay disc. indifference point, 16s delay0.60.63.2-0.30.00.3-0.5-0.20.5-1.8
Delay disc. indifference point, 2s delay0.10.10.10.3-0.10.3-0.3-0.20.3-0.3
Delay disc. indifference point, 24s delay0.10.10.50.1-0.20.3-0.4-0.30.4-0.7
Delay disc. indifference point, 4s delay0.50.52.10.4-0.50.6-0.5-0.40.5-1.5
Delay disc. indifference point, 8s delay0.50.50.8-0.50.6-0.60.80.9-0.7-0.9
Indifference point function ln k1.41.94.1-1.92.0-1.40.61.1-1.11.0
Indifference point function log k1.41.94.1-1.92.0-1.40.61.1-1.11.0
Patch foraging total patch changes 0 sec0.20.30.5-0.60.5-0.50.60.6-0.70.5
Patch foraging total patch changes 12 sec0.30.40.90.9-0.90.7-0.2-0.50.50.0
Patch foraging total patch changes 18 sec0.00.00.10.2-0.20.2-0.0-0.20.3-0.2
Patch foraging total patch changes 24 sec0.20.30.70.8-0.70.40.00.1-0.10.7
Patch foraging total patch changes 6 sec0.20.40.60.7-0.80.00.60.8-0.70.2
Patch foraging time to switch 0 sec0.60.91.40.8-1.01.0-1.2-0.91.0-0.7
Patch foraging water rate 0 sec1.72.83.6-1.91.9-1.81.71.6-1.70.9
Patch foraging water rate 12 sec3.45.36.5-2.42.5-2.32.11.9-2.22.6
Patch foraging water rate 18 sec0.40.50.8-0.80.9-0.70.60.3-0.60.9
Patch foraging water rate 24 sec0.30.41.70.7-0.10.2-0.4-0.60.11.3
Patch foraging water rate 6 sec0.40.61.7-0.80.9-0.70.60.4-0.61.3
Seeking ratio, delayed vs. immediate footshock1.41.62.6-1.01.2-1.41.31.5-1.60.5
Distance traveled before self-admin0.00.00.1-0.40.0-0.1-0.20.1-0.10.0
Distance traveled after self-admin2.02.33.4-1.91.6-1.61.41.1-1.41.4
Extensor digitorum longus weight7.127.933.6-5.35.4-5.85.85.8-5.62.7
Bone: elastic displacement0.10.10.1-0.30.2-0.30.20.3-0.3-0.2
Bone: elastic work0.10.20.7-0.40.10.0-0.3-0.10.2-0.8
Bone: endosteal estimation2.34.96.3-2.42.5-2.52.32.2-2.21.0
Bone: endosteal perimeter3.57.210.0-3.23.1-3.02.72.7-2.60.4
Epididymis fat weight0.10.30.60.6-0.80.50.2-0.30.30.7
Delta time in closed arm before/after self-admin0.10.10.3-0.60.5-0.20.1-0.20.1-0.5
Delta time in open arm before/after self-admin1.31.31.61.1-1.31.3-0.9-1.11.01.1
Diff in mean of infusions in LGA sessions0.60.61.4-0.20.4-0.81.01.2-1.0-0.6
Delay discount exponential model param0.30.42.10.4-0.30.1-0.1-0.30.11.5
Extinction: sum of active levers before priming0.70.71.00.8-0.90.9-1.0-1.00.90.4
Active lever presses in extinction session 60.10.10.40.4-0.1-0.0-0.1-0.1-0.20.6
Bone: final force0.91.43.1-1.81.6-1.31.01.0-0.9-0.1
Bone: final moment0.71.12.9-1.71.5-1.10.70.7-0.5-0.4
Food consumed during 24 hour testing period0.81.02.5-1.11.6-1.00.60.5-0.71.0
Glucose0.71.02.1-0.70.9-1.00.90.9-1.11.4
Heart weight0.40.51.3-1.10.7-0.81.00.4-0.4-0.3
Delay discount hyperbolic model param0.30.31.90.2-0.2-0.00.0-0.1-0.11.4
Intermittent access intake day 1-15 change0.60.63.70.40.1-0.00.00.2-0.31.9
Intermittent access intake escalation0.50.52.70.7-0.20.2-0.2-0.1-0.11.7
Intermittent access intake escalation 20.20.20.8-0.20.3-0.30.30.4-0.50.9
Intermitt. access day 1 inactive lever presses0.10.20.90.10.10.2-0.9-0.20.4-0.1
Intermitt. access day 15 inactive lever presses0.20.20.5-0.10.10.3-0.3-0.60.7-0.7
Intermitt. access escalation Index0.90.81.7-1.30.6-0.70.60.8-0.6-1.2
Intermittent access day 1 total infusions0.60.71.70.1-0.10.7-1.3-1.21.00.0
Intermittent access day 15 total infusions0.70.71.40.5-0.40.8-1.2-1.10.90.9
Intermittent access terminal intake (last 3 days)0.40.41.30.3-0.40.6-1.2-0.80.80.0
Intermittent access total infusions0.60.71.30.1-0.10.6-1.1-1.00.81.1
Intermittent access day 1 locomotion1.31.32.90.6-0.91.2-1.7-1.41.3-0.1
Intermittent access day 15 total locomotion0.80.92.3-0.1-0.20.8-1.5-1.21.2-0.2
Intermittent access total locomotion0.20.20.5-0.40.20.2-0.7-0.40.40.7
Intermittent access standard deviation0.40.40.90.4-0.30.5-1.0-0.80.70.4
Left kidney weight2.16.09.6-3.12.9-2.72.42.2-2.21.2
Right kidney weight1.13.14.3-2.01.8-1.92.11.7-1.80.8
Cocaine induced anxiety0.40.51.20.9-0.80.6-0.2-0.30.4-1.1
Post-drug Anxiety2.12.35.72.4-2.01.6-1.1-0.91.1-0.7
Baseline Anxiety0.70.81.51.2-1.11.0-0.8-0.60.60.5
Tail length0.41.13.71.2-1.20.8-0.5-0.2-0.01.9
Length with tail0.10.40.9-1.00.7-0.50.40.3-0.40.8
Length without tail1.73.610.0-3.22.7-1.91.40.8-0.6-1.2
Times rat made contact with spout0.10.10.30.10.20.2-0.4-0.60.5-0.2
Lifetime Intake0.60.71.40.3-0.30.7-1.2-1.10.90.9
Liver weight, left1.32.04.4-0.81.2-1.31.31.4-1.52.1
Liver weight, right2.44.05.9-1.01.4-1.92.12.4-2.42.2
Locomotor activity4.46.910.1-3.23.1-2.82.62.5-2.61.1
Locomotor testing distance2.84.77.3-2.72.6-2.22.12.0-2.01.3
Locomotor testing rearing0.91.41.7-1.11.2-1.21.31.2-1.21.2
Locomotion in novel chamber0.60.71.70.3-0.40.8-1.3-1.01.0-0.5
Locomotion in novel chamber post-restriction0.10.20.30.5-0.50.4-0.3-0.20.4-0.4
Fecal boli incidents, locomotor time 10.60.72.60.3-0.70.6-0.5-0.50.8-1.6
Change in fecal boli incidents, locomotor task1.91.83.4-1.61.8-1.40.80.9-1.31.2
Time >=10cm from walls, locomotor time 10.80.81.3-0.80.8-1.01.01.1-0.9-0.5
Bouts of movement, locomotor time 10.20.20.7-0.10.0-0.20.50.4-0.2-0.9
Total resting periods, locomotor time 10.10.10.7-0.0-0.1-0.10.30.2-0.0-0.8
Rest time, locomotor task time 10.50.52.5-0.1-0.20.4-0.7-0.30.7-1.6
Distance moved, locomotor task time 10.20.21.00.5-0.30.20.2-0.0-0.31.0
Vertical activity count, locomotor time 10.00.00.10.3-0.30.2-0.0-0.1-0.00.2
Time >=10cm from walls, locomotor time 20.30.31.5-0.50.3-0.10.20.20.1-1.2
Bouts of movement, locomotor time 20.80.81.6-0.50.4-1.01.31.2-1.10.4
Total resting periods, locomotor time 20.80.91.5-0.50.4-1.01.21.2-1.20.6
Rest time, locomotor task time 20.40.41.00.4-0.50.4-0.9-0.60.6-1.0
Distance moved, locomotor task time 20.20.31.00.3-0.2-0.10.40.5-0.61.0
Vertical activity count, locomotor time 20.50.50.80.9-0.80.9-0.8-0.70.60.3
Light reinforcement 11.73.05.1-2.01.7-1.82.31.8-1.7-0.6
Light reinforcement 20.70.91.90.0-0.20.7-1.4-1.21.3-1.0
Bone: marrow area2.45.26.9-2.62.6-2.52.32.3-2.21.0
Bone: maximum diameter2.85.29.9-3.13.1-2.51.91.9-1.80.3
Bone: maximum force1.01.73.6-1.91.6-1.41.21.1-0.9-0.2
Bone: maximum moment0.81.43.4-1.91.6-1.20.90.8-0.7-0.4
Mean time between licks in bursts0.81.22.11.1-0.91.2-1.4-1.11.2-0.2
Mean num. licks in bursts1.62.04.0-1.82.0-1.61.31.1-1.0-0.2
Cd content in liver0.10.10.50.3-0.70.30.0-0.0-0.0-0.4
Co content in liver0.40.42.70.2-0.30.2-0.1-0.20.4-1.6
Cu content in liver0.40.50.7-0.70.5-0.70.80.9-0.7-0.3
Fe content in liver0.70.81.91.4-1.10.8-0.5-0.70.40.9
K content in liver1.00.91.3-1.11.0-1.01.10.8-0.90.9
Mg content in liver2.62.63.3-1.81.6-1.81.81.7-1.70.6
Mn content in liver0.40.51.5-1.21.1-0.60.10.2-0.1-0.4
Na content in liver1.31.42.0-1.11.1-1.31.31.4-1.40.5
Rb content in liver2.53.15.0-1.21.4-1.71.91.7-1.92.2
Se content in liver0.40.50.90.6-0.70.8-0.7-0.90.70.7
Sr content in liver0.70.60.80.9-0.90.8-0.7-0.60.6-0.9
Zn content in liver0.50.52.30.1-0.20.3-0.6-0.50.7-1.5
Bone: minimum diameter0.50.92.1-1.51.2-0.60.10.00.2-1.4
Time in familiar zone, hab. session 10.10.10.8-0.10.10.10.1-0.20.3-0.9
Time in novel zone, hab. session 10.10.10.20.0-0.10.2-0.4-0.30.30.5
Total zone transitions, hab. session 10.30.41.21.1-0.90.6-0.0-0.30.30.1
Total locomotion distance, hab. session 10.20.20.70.8-0.50.20.40.1-0.20.6
Locomotion velocity, hab. session 10.10.20.30.6-0.2-0.10.60.2-0.30.6
Time in familiar zone, hab. session 20.10.20.70.3-0.30.2-0.2-0.20.10.8
Time in novel zone, hab. session 20.20.20.5-0.70.7-0.30.00.00.0-0.6
Total zone transitions, hab. session 20.20.30.60.8-0.70.00.70.4-0.4-0.4
Total locomotion distance, hab. session 20.30.30.90.5-0.4-0.31.00.7-0.6-0.5
Locomotion velocity, hab. session 20.20.30.60.5-0.4-0.20.80.5-0.4-0.7
Novel to familiar place preference ratio1.01.01.5-1.20.9-1.11.11.1-1.0-0.6
Novelty place preference1.21.21.9-1.41.1-1.21.21.1-1.0-0.6
Time in novel zone, NPP test1.41.52.6-1.61.3-1.31.31.2-1.1-0.3
Total zone transitions, NPP test0.20.20.60.4-0.2-0.20.80.5-0.5-0.5
Total locomotion distance, NPP test0.30.41.20.3-0.1-0.41.10.7-0.80.3
Locomotion velocity, NPP test0.20.30.70.8-0.60.00.80.4-0.50.2
Intraocular pressure0.00.00.2-0.1-0.00.2-0.0-0.10.10.5
Delta distance traveled before/after self-admin3.03.24.1-1.82.0-1.81.91.4-1.61.9
Delta ambulatory time before/after self-admin2.02.23.5-1.71.9-1.51.30.9-1.11.6
Parametrial fat weight0.50.91.41.2-0.71.0-1.0-0.80.71.2
Pavlov. Cond. lever latency0.50.62.2-0.91.0-0.3-0.3-0.1-0.11.5
Pavlov. Cond. magazine entry latency3.84.916.11.8-2.21.7-1.3-1.31.8-4.0
Pavlov. Cond. change in total contacts1.01.15.20.9-1.10.6-0.2-0.20.5-2.3
Pavlov. Cond. index score2.73.49.12.0-2.21.6-0.9-1.01.4-3.0
Pavlov. Cond. latency score2.02.66.81.8-2.01.3-0.7-0.81.1-2.6
Pavlov. Cond. lever contacts0.91.03.91.0-1.20.7-0.2-0.20.5-2.0
Pavlov. Cond. magazine entry number3.84.713.4-2.02.3-1.81.41.4-1.83.7
Pavlov. Cond. intertrial magazine entries0.91.15.50.6-0.0-0.40.60.8-1.02.3
Pavlov. Cond. lever-magazine prob. diff.2.53.18.91.8-2.11.4-0.8-0.81.2-3.0
Pavlov. Cond. response bias2.63.111.61.4-1.81.3-0.8-0.91.3-3.4
Pavlov. Cond. lever latency0.81.12.5-0.80.8-1.00.81.0-1.01.6
Pavlov. Cond. magazine entry latency4.14.75.72.0-2.12.3-2.3-2.42.4-1.5
Pavlov. Cond. change in total contacts0.91.21.41.2-1.01.1-1.1-1.11.1-1.1
Pavlov. Cond. index score1.72.12.71.3-1.41.5-1.4-1.61.5-1.3
Pavlov. Cond. latency score1.21.52.21.0-1.11.3-1.3-1.51.4-1.2
Pavlov. Cond. lever contacts0.60.92.60.7-0.80.8-0.7-0.80.8-1.6
Pavlov. Cond. magazine entry number3.23.94.7-2.02.0-2.12.12.2-2.11.2
Pavlov. Cond. intertrial magazine entries0.91.12.0-1.11.0-1.01.00.9-0.91.4
Pavlov. Cond. lever-magazine prob. diff.2.02.53.11.5-1.51.7-1.6-1.81.7-1.5
Pavlov. Cond. response bias1.82.54.11.5-1.61.6-1.4-1.41.5-2.0
Time in closed arm before self-admin0.20.20.60.5-0.30.3-0.4-0.20.4-0.8
Time in closed arm after self-admin0.00.00.2-0.10.4-0.20.20.1-0.1-0.1
Time in open arm before self-admin1.41.52.6-1.61.6-1.31.20.9-1.10.7
Time in open arm after self-admin0.20.21.3-0.30.10.1-0.2-0.30.11.1
Bone: periosteal estimation2.14.47.6-2.82.8-2.31.81.8-1.80.5
Bone: periosteal perimeter2.64.36.5-2.52.5-2.31.92.1-2.00.4
Bone: post-yield work0.20.30.7-0.30.3-0.50.80.6-0.70.4
Progressive ratio test 1 active lever presses0.30.31.4-0.50.5-0.40.10.2-0.21.2
Progressive ratio test 1 breakpoint0.10.10.5-0.20.2-0.0-0.4-0.10.20.7
Progressive ratio test 1 inactive lever presses0.80.82.40.6-0.10.6-1.2-0.90.81.6
Progressive ratio test 2 active lever presses0.60.71.3-1.11.0-0.80.40.5-0.51.1
Progressive ratio test 2 breakpoint0.91.01.9-1.31.2-0.90.50.7-0.61.4
Progressive ratio test 2 inactive lever presses0.50.61.4-0.30.20.6-1.1-1.21.10.2
Incentive Sensitization - Responses1.61.73.0-1.71.7-1.41.01.2-1.00.5
Incentive Sensitization - Breakpoint1.31.32.4-1.51.5-1.20.91.1-0.90.4
Sum of active levers in priming session hrs 5-60.20.20.4-0.30.3-0.40.50.3-0.30.7
Progressive ratio1.21.45.61.0-1.10.7-0.6-0.40.8-2.4
Food seeking constrained by brief footshock0.70.91.5-0.50.7-0.90.91.2-1.21.1
Seeking ratio, punishment vs. effort4.04.99.9-2.02.1-1.91.91.9-2.23.1
Retroperitoneal fat weight0.00.10.30.3-0.10.10.6-0.20.30.1
Reaction time number correct2.02.93.8-1.51.6-1.71.91.9-1.81.5
Reaction time mean minus median0.40.60.90.7-0.60.8-0.8-0.90.8-0.1
Reaction time mean minus median AUC1.11.42.51.2-1.11.3-1.2-1.61.30.1
Reaction time num false alarms0.20.20.50.5-0.70.6-0.3-0.40.40.4
Reaction time num false alarms AUC0.10.21.20.1-0.20.10.20.1-0.11.1
Reaction time trials correct on left2.02.93.8-1.51.6-1.71.91.9-1.81.5
Reaction time trials on left2.02.93.7-1.51.5-1.61.91.9-1.81.6
Reaction time mean3.04.25.61.9-1.92.2-2.4-2.32.3-1.3
Reaction time mean AUC3.14.15.41.9-1.92.2-2.3-2.22.2-1.2
Median of all reaction times3.75.16.62.0-2.12.4-2.6-2.62.6-1.5
Reaction time omissions0.00.00.20.2-0.20.10.0-0.10.00.4
Reaction time false alarm rate0.71.01.41.0-1.21.1-1.0-1.11.0-0.0
Reaction time premature initiation rate0.81.01.5-0.50.8-1.01.21.1-1.21.1
Reaction time premature initiations2.23.14.2-1.31.6-1.82.11.9-1.91.7
Std. dev. reaction times1.72.43.11.6-1.51.7-1.7-1.81.7-0.6
Reaction time trials completed2.02.93.7-1.51.5-1.61.91.9-1.81.6
Reaction time trials AUC1.82.63.3-1.41.5-1.51.81.8-1.61.5
Run reversals in cocaine runway, females0.10.10.2-0.40.20.00.30.00.10.5
Run reversals in cocaine runway, males0.50.51.30.30.1-0.30.80.7-0.81.2
Latency to leave start box in cocaine runway1.71.93.6-1.41.3-1.31.41.9-1.50.2
Latency to leave start box in cocaine runway, F0.60.61.6-0.30.4-0.60.81.3-1.00.7
Latency to leave start box in cocaine runway, M2.52.45.2-2.31.7-1.51.41.6-1.2-0.8
Std. dev. time between licks in bursts0.10.10.3-0.30.1-0.20.20.6-0.50.4
Total sessions with >9 infusions0.70.84.4-0.00.6-0.50.10.3-0.62.1
Short access day 1 total inactive lever presses1.41.55.2-1.21.3-0.90.40.6-0.82.3
Short access day 10 total inactive lever presses0.40.40.80.3-0.20.7-0.9-0.80.80.5
Short access day 1 total infusions0.10.10.4-0.1-0.10.2-0.6-0.30.20.5
Short access day 10 total infusions0.70.81.70.4-0.50.9-1.1-1.31.20.3
Short access total infusions0.81.01.80.7-0.60.9-1.4-1.31.00.8
Short access day 1 locomotion0.10.10.3-0.30.1-0.40.10.3-0.50.6
Short access day 10 total locomotion0.10.20.4-0.60.4-0.2-0.30.00.00.6
Short access total locomotion0.60.61.70.3-0.50.8-1.3-0.90.90.2
One hour access (0.3 mA shock)0.10.10.5-0.70.5-0.4-0.10.2-0.1-0.0
Compulsive drug intake0.50.51.0-0.50.8-0.80.51.0-0.80.2
One hour access (shock baseline)0.50.61.20.1-0.60.7-0.9-1.11.0-0.4
Social response proportion0.40.41.0-1.00.9-0.70.30.5-0.3-0.4
Social responses0.10.10.2-0.30.4-0.30.40.1-0.30.1
Social time0.20.20.5-0.70.5-0.40.5-0.0-0.30.7
Soleus weight14.542.654.8-6.36.4-7.17.17.4-7.13.4
Bone: stiffness1.72.62.9-1.51.7-1.71.61.5-1.61.7
Tibialis anterior weight12.843.751.1-6.97.1-7.26.76.8-6.84.3
Time to tail flick, vehicle, before self-admin0.70.72.41.6-1.50.6-0.30.1-0.1-0.4
Time to tail flick, vehicle, after self-admin0.40.40.9-0.90.8-0.80.20.5-0.40.6
Time to tail flick, test, before self-admin1.11.13.00.8-1.30.9-0.6-0.40.8-1.7
Time to tail flick, test, after self-admin1.01.01.41.1-1.11.2-1.2-1.10.90.1
Delta time to tail flick, vehicle, before/after SA0.40.41.6-1.31.0-0.4-0.3-0.20.30.1
Delta time to tail flick, test, before/after SA0.30.31.2-0.40.6-0.1-0.4-0.3-0.01.1
Tibia length0.30.82.8-1.00.9-0.2-0.4-0.50.6-1.7
Ambulatory time before self-admin0.20.20.40.3-0.60.6-0.6-0.50.5-0.2
Ambulatory time after self-admin1.51.62.9-1.71.5-1.21.00.6-0.91.6
Bone: tissue strength1.21.22.00.8-0.91.1-1.2-1.41.3-0.8
Total heroin consumption1.41.72.5-0.40.8-1.21.51.5-1.51.6
Bone: trabecular number0.60.91.41.2-1.21.0-0.9-1.10.90.1
Bone: trabecular spacing0.10.10.60.2-0.30.2-0.2-0.00.1-0.8
Bone: trabecular thickness0.40.51.4-1.21.1-0.50.1-0.0-0.00.6
Bone: trabecular tissue density7.610.718.5-4.34.2-3.52.92.8-2.81.5
Water consumed over 24 hours0.30.40.70.2-0.10.4-0.7-0.80.7-0.7
Number of responses in last shaping day0.00.00.1-0.10.2-0.0-0.00.3-0.10.3