chr1:171,727,837-174,867,483

Trait: Tibialis anterior weight

Best TWAS P=1.11e-08 · Best GWAS P=1.78e-08 conditioned to 1.00e+00

Associated models

Tissue Gene RNA modality RNA phenotype h2 # weights Model R2 Model R2 P TWAS Z TWAS P Coloc P Joint
Adipose Vps35l gene expression ENSRNOG00000016063 0.05 1 0.03 6.5e-04 -5.51 3.52e-08 0.18 FALSE
Adipose Iqck gene expression ENSRNOG00000036758 0.38 16 0.28 1.0e-31 -5.15 2.63e-07 0.68 TRUE
Adipose Vps35l mRNA stability ENSRNOG00000016063 0.06 2623 0.01 3.4e-02 -5.35 8.63e-08 0.54 FALSE
Brain Knop1 gene expression ENSRNOG00000070112 0.07 1 0.06 3.3e-06 5.3 1.18e-07 0.4 FALSE
Eye Ccp110 gene expression ENSRNOG00000027405 0.55 5 0.08 2.3e-02 5.12 3.00e-07 0.33 TRUE
IL Gpr139 gene expression ENSRNOG00000023863 0.22 3 0.04 4.0e-02 5.48 4.27e-08 0.28 FALSE
LHb Knop1 gene expression ENSRNOG00000070112 0.21 1 0.03 7.4e-02 5.37 8.01e-08 0.05 FALSE
Liver Rps15a isoform ratio ENSRNOT00000092282 0.24 57 0.14 1.3e-15 -5.4 6.69e-08 0.67 FALSE
Liver Rps15a isoform ratio ENSRNOT00000092513 0.25 56 0.15 4.6e-16 5.37 7.95e-08 0.65 FALSE
Liver Rps15a intron excision ratio chr1:172426036:172426864 0.16 1 0.09 2.9e-10 5.3 1.13e-07 0.67 FALSE
Liver Rps15a intron excision ratio chr1:172426036:172426971 0.18 33 0.11 1.3e-12 -5.36 8.11e-08 0.64 FALSE
Liver RGD1559600 intron excision ratio chr1:173974388:173985543 0.51 1 0.01 1.3e-02 5.55 2.79e-08 0.11 FALSE
Liver RGD1559600 intron excision ratio chr1:173974388:173987413 0.53 2 0.01 3.5e-02 -5.71 1.11e-08 0.41 TRUE
NAcc Ccp110 isoform ratio ENSRNOT00000037870 0.04 2570 0.04 4.9e-04 5.21 1.92e-07 0.61 FALSE
NAcc Ccp110 intron excision ratio chr1:173066008:173068203 0.06 1 0.07 9.6e-06 5.36 8.26e-08 0.36 FALSE
NAcc Ccp110 intron excision ratio chr1:173066008:173071013 0.06 1 0.07 6.9e-06 5.36 8.26e-08 0.42 FALSE
OFC Tmc7 gene expression ENSRNOG00000016679 0.29 1 0.14 4.3e-04 5.39 6.93e-08 0.06 FALSE
OFC Coq7 mRNA stability ENSRNOG00000017012 0.26 13 0.09 4.0e-03 -5.54 2.99e-08 0.41 TRUE
PL Rps15a alternative TSS ENSRNOT00000092282 0.03 1 0.05 7.6e-05 -5.11 3.14e-07 0.05 TRUE
PL Gpr139 gene expression ENSRNOG00000023863 0.03 1 0.02 1.0e-02 5.44 5.38e-08 0.04 TRUE
PL Knop1 gene expression ENSRNOG00000070112 0.1 2558 0.07 3.4e-06 5.19 2.13e-07 0.65 FALSE
PL Eri2 isoform ratio ENSRNOT00000119035 0.08 7 0.06 3.8e-05 5.45 5.07e-08 0.62 FALSE
PL Tmc7 mRNA stability ENSRNOG00000016679 0.07 1 0.07 7.9e-06 5.5 3.84e-08 0.65 FALSE