Hub : Traits : Tibialis anterior weight : →

chr1:181,162,118-184,410,771

Trait: Tibialis anterior weight

Best TWAS P = 6.97e-09 · Best GWAS P= 8.56e-09 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Gprc5b	gene expression	Gprc5b	0.41	2688	0.25	7.3e-28	5.79	6.97e-09	0.65	TRUE
Adipose	Iqck	gene expression	Iqck	0.38	11	0.27	9.2e-30	-5.42	5.96e-08	0.65	TRUE
Adipose	LOC134485172	gene expression	LOC134485172	0.08	1	0.06	1.0e-06	-5.58	2.40e-08	0.53	FALSE
Adipose	Vps35l	gene expression	Vps35l	0.04	1	0.01	1.3e-02	5.61	2.03e-08	0.06	FALSE
Adipose	Vps35l	mRNA stability	Vps35l	0.06	1	0.03	6.5e-04	5.59	2.21e-08	0.08	FALSE
BLA	LOC120099916	gene expression	LOC120099916	0.17	51	0.18	1.0e-09	5.26	1.47e-07	0.49	FALSE
BLA	LOC134485174	gene expression	LOC134485174	0.13	1	0.08	7.1e-05	-5.38	7.32e-08	0.19	TRUE
Brain	Knop1	gene expression	Knop1	0.04	1	0.01	2.1e-02	-5.63	1.85e-08	0.04	FALSE
Brain	Eri2	isoform ratio	XR_010058163.1	0.12	13	0.06	7.1e-06	5.38	7.57e-08	0.54	TRUE
Eye	Eri2	alternative polyA	XM_039091608.2	0.29	1	0.15	2.7e-03	-5.45	5.06e-08	0.06	FALSE
Eye	Coq7	intron excision ratio	chr1_182275411_182285237	0.43	1	0.17	1.6e-03	-5.5	3.73e-08	0.06	FALSE
IC	Lyrm1	alternative TSS	NM_001276487.1	0.16	1	0.12	1.1e-05	-5.5	3.86e-08	0.78	FALSE
IC	LOC134485174	gene expression	LOC134485174	0.09	18	0.05	3.9e-03	5.52	3.47e-08	0.44	TRUE
IL	Gpr139	gene expression	Gpr139	0.21	1	0.06	1.5e-02	-5.49	4.02e-08	0.05	FALSE
Liver	RGD1559600	alternative TSS	NM_001109153.1	0.11	1	0.03	1.1e-04	-5.43	5.65e-08	0.18	FALSE
Liver	RGD1559600	alternative TSS	XM_006230140.4	0.1	1	0.03	1.3e-04	5.43	5.65e-08	0.17	FALSE
Liver	Gde1	gene expression	Gde1	0.39	18	0.19	6.8e-21	-5.24	1.59e-07	0.61	FALSE
Liver	RGD1559600	intron excision ratio	chr1_183405725_183416880	0.44	1	0.02	1.3e-03	-5.43	5.65e-08	0.08	FALSE
Liver	RGD1559600	intron excision ratio	chr1_183405725_183418750	0.33	41	0.01	4.9e-02	-5.57	2.59e-08	0.41	FALSE
Liver	Rps15a	intron excision ratio	chr1_181860280_181861108	0.17	1	0.09	9.8e-10	-5.61	2.07e-08	0.76	FALSE
Liver	Rps15a	intron excision ratio	chr1_181860280_181861215	0.19	36	0.11	2.7e-12	5.63	1.82e-08	0.66	FALSE
NAcc	Knop1	gene expression	Knop1	0.06	21	0.08	2.2e-12	5.59	2.24e-08	0.66	FALSE
NAcc	LOC120099917	gene expression	LOC120099917	0.08	6	0.04	1.2e-06	5.38	7.46e-08	0.62	FALSE
NAcc	Lyrm1	isoform ratio	NM_001276487.1	0.03	22	0.02	1.6e-04	5.45	5.16e-08	0.04	FALSE
NAcc	Ccp110	intron excision ratio	chr1_182500176_182502371	0.03	1	0.03	2.7e-05	-5.46	4.88e-08	0.33	FALSE
PL	LOC134485174	gene expression	LOC134485174	0.05	3221	0.04	6.0e-05	5.23	1.72e-07	0.64	FALSE
PL	Syt17	isoform ratio	XM_006230104.2	0.05	1	0.03	5.2e-04	5.56	2.62e-08	0.36	FALSE
PL	Syt17	intron excision ratio	chr1_182191400_182191628	0.03	2706	0.02	1.8e-03	-5.36	8.46e-08	0.59	FALSE
PL	Syt17	intron excision ratio	chr1_182191405_182191628	0.02	2706	0.01	7.6e-03	5.39	6.92e-08	0.48	FALSE
PL	Tmc7	mRNA stability	Tmc7	0.02	1	0.01	1.4e-02	-5.37	7.73e-08	0.03	FALSE
pVTA	Lyrm1	alternative TSS	NM_001276487.1	0.07	1	0.03	1.5e-03	-5.5	3.86e-08	0.79	FALSE
pVTA	Gde1	gene expression	Gde1	0.06	13	0.05	3.8e-05	5.52	3.41e-08	0.6	FALSE
pVTA	Knop1	gene expression	Knop1	0.06	27	0.03	1.9e-03	-5.43	5.73e-08	0.56	FALSE
pVTA	LOC134485174	gene expression	LOC134485174	0.04	1	0.02	9.7e-03	-5.63	1.82e-08	0.08	FALSE
pVTA	Syt17	isoform ratio	XM_017588770.3	0.04	1	0.03	1.1e-03	-5.52	3.31e-08	0.05	FALSE
pVTA	Lyrm1	intron excision ratio	chr1_183716957_183729651	0.05	1	0	1.6e-01	5.5	3.86e-08	0.44	FALSE
pVTA	Rps15a	intron excision ratio	chr1_181860280_181861108	0.1	15	0.08	5.1e-07	5.59	2.21e-08	0.67	FALSE
pVTA	Rps15a	intron excision ratio	chr1_181860280_181861215	0.05	1	0.04	2.0e-04	5.63	1.85e-08	0.34	FALSE
pVTA	Tmc7	intron excision ratio	chr1_182318507_182320753	0.03	1	0.03	2.2e-03	-5.41	6.25e-08	0.04	FALSE