Hub : Genes

LOC120097030

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression LOC120097030 0.04 0.05 3.2e-04 0.02 0.03 0.03 0.03 1.1e-03 3.5e-04 5.0e-04 2.2e-04
2 PL mRNA stability LOC120097030 0.06 0.06 3.4e-06 0.05 0.05 0.05 0.05 2.1e-06 4.6e-06 4.8e-06 3.9e-06
3 Brain gene expression LOC120097030 0.08 0.07 6.4e-07 0.07 0.07 0.06 0.07 4.1e-07 5.6e-07 1.2e-06 9.1e-07
4 IL mRNA stability LOC120097030 0.19 0.17 4.2e-03 0.06 0.05 0.02 0.03 1.2e-02 2.4e-02 1.2e-01 7.4e-02
5 BLA mRNA stability LOC120097030 0.09 0.08 1.1e-03 0.02 0.03 0.01 0.01 2.0e-02 1.4e-02 1.5e-01 5.0e-02
6 NAcc gene expression LOC120097030 0.03 0.03 5.0e-04 0.01 0.01 0.01 0.01 2.4e-03 1.8e-03 1.0e-02 9.3e-03
7 NAcc mRNA stability LOC120097030 0.03 0.04 5.5e-04 0.01 0.02 0.02 0.02 2.6e-03 1.3e-03 6.4e-04 1.2e-03
8 Brain mRNA stability LOC120097030 0.19 0.16 2.6e-13 0.15 0.15 0.14 0.14 9.8e-14 9.2e-14 2.9e-13 1.8e-13
9 OFC mRNA stability LOC120097030 0.24 0.19 7.5e-04 0.1 0.1 0.06 0.08 2.5e-03 2.5e-03 1.2e-02 6.5e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density1.12.02.2-1.5-1.5-1.4-1.41.4-1.4-1.41.4-1.3
Area under the delay curve0.10.10.10.20.20.40.4-0.30.30.3-0.30.3
BMI with tail0.41.51.71.31.31.21.2-1.21.21.2-1.21.1
BMI without tail0.00.00.10.10.10.10.10.0-0.0-0.10.1-0.3
Body weight0.72.93.21.81.81.71.7-1.71.71.7-1.71.6
Weight adjusted by age0.82.22.31.41.41.51.5-1.51.51.5-1.51.5
Bone surface0.51.01.2-1.1-1.1-1.0-1.01.0-1.0-1.01.0-0.7
Bone volume0.61.21.4-1.2-1.2-1.1-1.11.1-1.1-1.11.1-0.9
Breakpoint value in progressive ratio session0.00.10.10.20.20.30.3-0.30.30.3-0.30.3
Number of licking bursts0.00.00.0-0.0-0.0-0.1-0.10.0-0.0-0.00.0-0.1
Context. condit. distance diff. score0.91.11.5-1.0-1.0-1.0-1.01.1-1.1-1.11.1-1.2
Locomotion velocity, session 10.20.20.30.40.40.50.5-0.40.40.5-0.40.5
Locomotion distance, session 10.00.00.1-0.1-0.1-0.1-0.10.1-0.1-0.20.1-0.3
Locomotion velocity, session 20.00.00.0-0.2-0.2-0.1-0.10.2-0.2-0.10.1-0.2
Locomotion distance, session 20.00.00.1-0.3-0.3-0.1-0.10.1-0.1-0.10.1-0.2
Locomotion velocity, session 30.50.50.70.60.60.80.8-0.70.70.7-0.70.8
Locomotion distance, session 30.00.00.0-0.2-0.2-0.1-0.10.2-0.2-0.20.2-0.1
Stereotopy head waving bouts, day 30.60.80.90.80.81.01.0-0.90.90.9-0.90.8
Stereotopy head waving duration, day 32.42.93.01.71.71.71.7-1.71.71.7-1.71.6
Locomotion velocity, session 74.34.85.4-2.3-2.3-2.1-2.12.2-2.2-2.12.2-2.1
Locomotion distance, session 73.34.34.9-2.2-2.2-2.0-2.02.0-2.0-2.02.1-2.0
Stereotopy head waving bouts, day 71.51.71.91.21.21.31.3-1.31.41.4-1.41.4
Stereotopy head waving duration, day 72.12.63.01.61.61.51.5-1.61.61.6-1.61.7
Locomotion velocity, session 80.00.00.1-0.2-0.20.00.00.1-0.1-0.00.1-0.0
Locomotion distance, session 80.71.01.4-1.0-1.0-0.9-0.91.0-1.0-0.91.0-1.2
Degree of sensitization distance4.34.65.0-2.2-2.2-2.1-2.12.1-2.1-2.12.2-2.1
Degree of sensitization stereotypy1.11.21.31.01.01.01.0-1.11.11.1-1.11.1
Conditioned locomotion0.00.00.1-0.2-0.2-0.2-0.20.2-0.2-0.20.2-0.2
Cocaine response after cond. corrected0.20.30.30.50.50.60.6-0.50.50.5-0.50.5
Cocaine response after cond. not corrected0.10.20.20.30.30.40.4-0.40.40.4-0.40.4
Cocaine response before conditioning0.10.20.2-0.4-0.4-0.4-0.40.4-0.4-0.40.4-0.5
Saline control response0.10.10.1-0.3-0.3-0.3-0.30.3-0.3-0.40.3-0.2
Bone: connectivity density2.33.73.8-1.9-1.9-1.9-1.91.9-1.9-1.91.9-1.9
Bone: cortical apparent density0.10.10.1-0.2-0.2-0.3-0.30.3-0.3-0.30.4-0.3
Bone: cortical area0.00.00.1-0.3-0.30.00.00.0-0.00.00.00.1
Bone: cortical porosity1.21.31.41.11.11.11.1-1.11.11.1-1.21.1
Bone: cortical porosity0.70.70.80.80.80.90.9-0.90.90.9-0.90.8
Bone: cortical thickness0.00.00.1-0.3-0.3-0.0-0.00.1-0.1-0.00.10.1
Bone: cortical thickness0.00.00.1-0.3-0.3-0.0-0.00.1-0.1-0.00.1-0.3
Bone: cortical tissue density0.10.10.2-0.3-0.3-0.3-0.30.3-0.4-0.30.4-0.4
Condit. Reinf. active minus inactive responses0.40.50.60.60.60.70.7-0.70.70.7-0.70.6
Condit. Reinf. active-inactive response ratio2.02.22.41.31.31.61.6-1.51.51.5-1.51.4
Condit. Reinf. active responses0.00.00.0-0.0-0.00.10.1-0.00.00.0-0.1-0.0
Condit. Reinf. inactive responses2.22.83.0-1.6-1.6-1.7-1.71.7-1.7-1.71.7-1.7
Incentive salience index mean0.70.91.00.90.91.01.0-0.90.91.0-1.00.8
Condit. Reinf. lever presses0.20.40.40.60.60.70.7-0.60.60.6-0.70.4
Condit. Reinf. active minus inactive responses0.30.40.4-0.7-0.7-0.7-0.70.7-0.7-0.70.7-0.6
Condit. Reinf. active-inactive response ratio0.00.10.10.20.20.20.2-0.20.20.2-0.20.3
Condit. Reinf. active responses0.81.21.2-1.1-1.1-1.1-1.11.1-1.1-1.11.1-1.1
Condit. Reinf. inactive responses1.72.52.7-1.5-1.5-1.6-1.61.6-1.6-1.61.6-1.7
Condit. Reinf. lever presses0.10.20.3-0.4-0.4-0.5-0.50.4-0.4-0.40.4-0.6
Condit. Reinf. lever reinforcers received0.60.90.9-0.9-0.9-1.0-1.01.0-1.0-1.00.9-0.9
Conditioned reinforcement - actives0.41.71.8-1.3-1.3-1.3-1.31.3-1.3-1.31.3-1.3
Conditioned reinforcement - inactives1.74.64.7-2.2-2.2-2.1-2.12.2-2.1-2.12.1-2.1
Conditioned locomotion0.10.20.3-0.6-0.6-0.4-0.40.4-0.4-0.40.4-0.4
Patch foraging indifference point 0 sec1.02.83.2-1.8-1.8-1.7-1.71.7-1.7-1.81.7-1.2
Patch foraging indifference point AUC0.10.30.40.60.60.60.6-0.50.50.5-0.50.5
Delay disc. indifference point, 0s delay0.30.30.5-0.6-0.6-0.5-0.50.6-0.6-0.70.6-0.5
Delay disc. indifference point, 16s delay0.20.20.3-0.5-0.5-0.4-0.40.5-0.5-0.40.5-0.5
Delay disc. indifference point, 2s delay1.51.61.71.31.31.31.3-1.31.31.3-1.31.3
Delay disc. indifference point, 24s delay0.10.20.30.40.40.50.5-0.40.40.5-0.40.4
Delay disc. indifference point, 4s delay1.81.92.11.31.31.51.5-1.31.31.3-1.41.4
Delay disc. indifference point, 8s delay0.00.00.0-0.2-0.2-0.1-0.10.2-0.2-0.20.2-0.2
Indifference point function ln k0.00.00.0-0.1-0.1-0.0-0.00.0-0.0-0.0-0.0-0.2
Indifference point function log k0.00.00.0-0.1-0.1-0.0-0.00.0-0.0-0.0-0.0-0.2
Patch foraging total patch changes 0 sec0.72.02.2-1.5-1.5-1.4-1.41.5-1.5-1.51.4-1.0
Patch foraging total patch changes 12 sec0.50.70.9-0.8-0.8-0.9-0.90.9-0.9-1.00.8-0.5
Patch foraging total patch changes 18 sec0.81.92.2-1.4-1.4-1.3-1.31.4-1.4-1.51.4-1.2
Patch foraging total patch changes 24 sec0.00.00.10.10.1-0.0-0.0-0.00.0-0.0-0.10.3
Patch foraging total patch changes 6 sec0.10.30.4-0.5-0.5-0.5-0.50.5-0.5-0.60.5-0.3
Patch foraging time to switch 0 sec0.31.11.4-0.9-0.9-1.2-1.21.1-1.1-1.01.1-1.1
Patch foraging water rate 0 sec0.10.50.60.60.60.80.8-0.80.80.8-0.80.7
Patch foraging water rate 12 sec0.21.01.20.80.81.11.1-1.01.01.0-1.01.0
Patch foraging water rate 18 sec1.94.24.32.02.02.02.0-2.12.12.1-2.12.0
Patch foraging water rate 24 sec0.10.20.30.40.40.50.5-0.50.50.5-0.50.3
Patch foraging water rate 6 sec2.02.93.21.61.61.81.8-1.71.71.7-1.71.8
Seeking ratio, delayed vs. immediate footshock0.71.01.1-1.0-1.0-1.1-1.11.0-1.0-1.01.0-1.0
Distance traveled before self-admin0.51.01.11.01.01.01.0-1.01.01.0-1.01.1
Distance traveled after self-admin1.83.23.41.91.91.71.7-1.81.81.8-1.81.7
Extensor digitorum longus weight12.650.551.17.17.17.27.2-7.17.17.1-7.17.0
Bone: elastic displacement0.40.50.6-0.8-0.8-0.7-0.70.7-0.7-0.70.7-0.8
Bone: elastic work0.20.30.5-0.7-0.7-0.5-0.50.5-0.5-0.50.5-0.5
Bone: endosteal estimation0.10.10.20.30.30.40.4-0.40.40.4-0.40.5
Bone: endosteal perimeter0.00.10.20.20.20.30.3-0.30.30.3-0.30.4
Epididymis fat weight0.62.83.5-1.7-1.7-1.7-1.71.6-1.6-1.61.6-1.9
Delta time in closed arm before/after self-admin4.03.73.9-1.9-1.9-1.9-1.92.0-2.0-2.01.9-1.9
Delta time in open arm before/after self-admin0.10.10.10.20.20.30.3-0.30.30.3-0.30.2
Diff in mean of infusions in LGA sessions0.61.11.11.01.01.11.1-1.01.01.0-1.01.0
Delay discount exponential model param0.30.40.6-0.6-0.6-0.7-0.70.6-0.6-0.60.6-0.6
Extinction: sum of active levers before priming1.62.52.7-1.6-1.6-1.6-1.61.5-1.5-1.51.5-1.5
Active lever presses in extinction session 60.70.70.7-0.8-0.8-0.7-0.70.8-0.8-0.80.8-0.8
Bone: final force0.10.20.20.30.30.40.4-0.40.40.4-0.40.5
Bone: final moment0.10.10.20.10.10.40.4-0.30.30.4-0.40.4
Food consumed during 24 hour testing period0.20.40.5-0.7-0.7-0.6-0.60.6-0.6-0.60.5-0.7
Glucose0.00.00.0-0.1-0.1-0.0-0.00.0-0.0-0.00.10.1
Heart weight0.30.50.6-0.8-0.8-0.7-0.70.8-0.8-0.80.7-0.5
Delay discount hyperbolic model param0.40.50.7-0.7-0.7-0.8-0.80.7-0.7-0.70.7-0.7
Intermittent access intake day 1-15 change0.63.53.6-1.9-1.9-1.9-1.91.9-1.9-1.91.9-1.9
Intermittent access intake escalation0.73.73.8-2.0-2.0-1.9-1.91.9-1.9-1.91.9-1.9
Intermittent access intake escalation 21.01.71.9-1.4-1.4-1.3-1.31.3-1.3-1.31.3-1.3
Intermitt. access day 1 inactive lever presses0.00.00.0-0.1-0.1-0.1-0.10.1-0.1-0.10.1-0.1
Intermitt. access day 15 inactive lever presses0.00.00.0-0.2-0.2-0.2-0.20.2-0.2-0.20.2-0.2
Intermitt. access escalation Index0.00.00.10.20.20.20.2-0.20.20.2-0.20.2
Intermittent access day 1 total infusions0.00.00.0-0.0-0.00.00.0-0.00.00.0-0.00.0
Intermittent access day 15 total infusions1.02.52.8-1.7-1.7-1.6-1.61.6-1.6-1.61.6-1.6
Intermittent access terminal intake (last 3 days)0.81.41.6-1.3-1.3-1.2-1.21.2-1.2-1.21.2-1.2
Intermittent access total infusions1.31.51.7-1.3-1.3-1.2-1.21.2-1.2-1.21.2-1.2
Intermittent access day 1 locomotion0.00.00.0-0.1-0.1-0.1-0.10.1-0.1-0.10.1-0.0
Intermittent access day 15 total locomotion0.10.40.5-0.7-0.7-0.6-0.60.7-0.7-0.60.7-0.7
Intermittent access total locomotion0.10.10.2-0.4-0.4-0.3-0.30.4-0.4-0.30.4-0.4
Intermittent access standard deviation0.10.30.4-0.6-0.6-0.5-0.50.6-0.6-0.50.5-0.5
Left kidney weight0.00.20.30.60.60.50.5-0.50.50.5-0.50.4
Right kidney weight0.00.20.40.40.40.30.3-0.30.30.3-0.40.7
Cocaine induced anxiety0.00.00.00.10.10.00.0-0.10.10.0-0.10.2
Post-drug Anxiety0.80.91.0-1.0-1.0-1.0-1.01.0-1.0-1.00.9-0.9
Baseline Anxiety0.30.50.6-0.7-0.7-0.7-0.70.7-0.7-0.70.7-0.8
Tail length0.41.92.1-1.4-1.4-1.3-1.31.4-1.4-1.41.4-1.3
Length with tail0.10.20.40.50.50.40.4-0.50.50.5-0.50.6
Length without tail1.47.48.22.72.72.62.6-2.72.72.7-2.72.9
Times rat made contact with spout0.60.70.8-0.8-0.8-0.8-0.80.8-0.8-0.80.8-0.9
Lifetime Intake0.70.91.2-1.1-1.1-0.9-0.90.9-0.9-0.90.9-0.9
Liver weight, left1.73.03.31.81.81.71.7-1.71.71.7-1.81.5
Liver weight, right0.50.80.90.90.90.90.9-0.90.91.0-0.90.6
Locomotor activity1.82.83.01.71.71.71.7-1.61.61.6-1.71.6
Locomotor testing distance0.00.00.1-0.1-0.1-0.1-0.10.2-0.2-0.20.1-0.2
Locomotor testing rearing0.00.20.3-0.4-0.4-0.4-0.40.4-0.4-0.50.3-0.4
Locomotion in novel chamber0.40.60.6-0.8-0.8-0.7-0.70.8-0.8-0.80.8-0.7
Locomotion in novel chamber post-restriction0.41.11.21.01.01.01.0-1.11.11.1-1.11.1
Fecal boli incidents, locomotor time 10.51.41.51.21.21.11.1-1.21.21.2-1.21.2
Change in fecal boli incidents, locomotor task0.20.20.30.50.50.50.5-0.50.50.5-0.50.5
Time >=10cm from walls, locomotor time 10.91.11.1-1.1-1.1-1.0-1.01.1-1.1-1.11.1-1.0
Bouts of movement, locomotor time 14.15.35.62.42.42.42.4-2.32.32.2-2.32.2
Total resting periods, locomotor time 14.45.15.42.32.32.32.3-2.22.22.2-2.22.2
Rest time, locomotor task time 11.42.32.41.51.51.51.5-1.51.51.5-1.51.5
Distance moved, locomotor task time 11.23.33.6-1.9-1.9-1.7-1.71.9-1.9-1.71.9-1.8
Vertical activity count, locomotor time 10.21.11.2-1.1-1.1-1.0-1.01.0-1.0-1.01.0-1.0
Time >=10cm from walls, locomotor time 20.20.50.50.60.60.70.7-0.70.70.6-0.70.7
Bouts of movement, locomotor time 21.65.25.42.32.32.32.3-2.32.32.2-2.22.2
Total resting periods, locomotor time 21.45.65.82.42.42.42.4-2.42.42.3-2.32.3
Rest time, locomotor task time 20.71.21.31.21.21.11.1-1.11.11.1-1.11.0
Distance moved, locomotor task time 22.73.64.1-2.0-2.0-1.8-1.81.9-1.9-1.91.9-1.8
Vertical activity count, locomotor time 20.20.50.6-0.8-0.8-0.7-0.70.7-0.7-0.80.7-0.6
Light reinforcement 11.25.36.5-2.3-2.3-2.3-2.32.3-2.3-2.22.3-2.5
Light reinforcement 20.61.41.8-1.2-1.2-1.2-1.21.2-1.2-1.11.2-1.3
Bone: marrow area0.00.10.10.20.20.20.2-0.20.30.2-0.30.4
Bone: maximum diameter0.30.61.00.60.60.80.8-0.80.80.8-0.81.0
Bone: maximum force0.20.50.70.40.40.70.7-0.70.70.7-0.70.9
Bone: maximum moment0.10.30.50.20.20.60.6-0.50.50.6-0.60.7
Mean time between licks in bursts0.52.84.1-1.5-1.5-1.7-1.71.6-1.6-1.61.6-2.0
Mean num. licks in bursts0.10.30.4-0.6-0.6-0.5-0.50.6-0.6-0.60.6-0.6
Cd content in liver1.11.31.51.11.11.11.1-1.11.11.1-1.11.2
Co content in liver4.95.86.32.42.42.42.4-2.42.42.4-2.42.5
Cu content in liver0.40.50.60.60.60.70.7-0.70.70.6-0.60.8
Fe content in liver1.51.92.0-1.4-1.4-1.4-1.41.4-1.4-1.41.4-1.1
K content in liver1.11.11.2-1.1-1.1-1.1-1.11.1-1.1-1.11.1-1.0
Mg content in liver2.52.82.8-1.7-1.7-1.7-1.71.7-1.7-1.71.7-1.6
Mn content in liver2.52.82.8-1.7-1.7-1.7-1.71.7-1.7-1.71.7-1.6
Na content in liver0.91.01.31.01.01.01.0-1.01.01.0-1.11.1
Rb content in liver0.00.00.0-0.2-0.2-0.2-0.20.1-0.1-0.20.2-0.0
Se content in liver0.91.11.2-1.1-1.1-1.1-1.11.0-1.0-1.11.0-1.0
Sr content in liver0.00.00.0-0.2-0.2-0.1-0.10.2-0.2-0.20.10.0
Zn content in liver0.10.10.2-0.4-0.4-0.4-0.40.4-0.4-0.40.4-0.2
Bone: minimum diameter0.10.20.40.30.30.50.5-0.50.50.5-0.50.7
Time in familiar zone, hab. session 10.00.00.10.20.20.10.1-0.20.20.2-0.20.2
Time in novel zone, hab. session 11.11.21.31.11.11.11.1-1.11.11.1-1.11.1
Total zone transitions, hab. session 10.20.20.30.40.40.60.6-0.50.50.5-0.50.4
Total locomotion distance, hab. session 10.00.00.0-0.1-0.10.00.00.1-0.1-0.10.0-0.1
Locomotion velocity, hab. session 10.10.10.2-0.4-0.4-0.3-0.30.4-0.4-0.40.3-0.4
Time in familiar zone, hab. session 21.82.12.21.41.41.51.5-1.41.41.5-1.41.4
Time in novel zone, hab. session 20.60.70.8-0.8-0.8-0.9-0.90.8-0.8-0.90.8-0.8
Total zone transitions, hab. session 21.31.71.91.41.41.31.3-1.31.31.3-1.41.1
Total locomotion distance, hab. session 20.20.30.40.60.60.60.6-0.50.50.5-0.60.4
Locomotion velocity, hab. session 20.60.70.80.90.90.90.9-0.90.90.8-0.90.7
Novel to familiar place preference ratio1.21.61.7-1.2-1.2-1.3-1.31.3-1.3-1.31.2-1.3
Novelty place preference1.01.31.3-1.1-1.1-1.2-1.21.1-1.1-1.21.1-1.1
Time in novel zone, NPP test0.50.70.7-0.8-0.8-0.8-0.80.8-0.8-0.80.8-0.8
Total zone transitions, NPP test0.10.20.4-0.4-0.4-0.4-0.40.5-0.5-0.50.4-0.6
Total locomotion distance, NPP test2.53.53.9-1.8-1.8-1.9-1.91.9-1.9-1.91.8-2.0
Locomotion velocity, NPP test2.43.53.9-1.8-1.8-1.8-1.81.9-1.9-1.91.8-2.0
Intraocular pressure0.50.81.5-0.9-0.9-0.9-0.90.8-0.8-0.80.8-1.2
Delta distance traveled before/after self-admin2.73.03.11.81.81.81.8-1.81.71.8-1.71.7
Delta ambulatory time before/after self-admin1.93.43.51.91.91.81.8-1.81.81.8-1.81.8
Parametrial fat weight1.74.14.2-2.0-2.0-2.1-2.12.0-2.0-2.02.0-1.9
Pavlov. Cond. lever latency0.00.00.00.10.1-0.0-0.00.0-0.0-0.00.00.1
Pavlov. Cond. magazine entry latency0.00.00.1-0.2-0.2-0.1-0.10.2-0.2-0.20.2-0.2
Pavlov. Cond. change in total contacts1.11.11.31.01.01.21.2-1.11.11.1-1.10.9
Pavlov. Cond. index score0.10.10.10.20.20.30.3-0.30.30.3-0.30.2
Pavlov. Cond. latency score0.00.00.00.10.10.20.2-0.20.20.2-0.20.1
Pavlov. Cond. lever contacts0.00.00.1-0.2-0.2-0.1-0.10.1-0.1-0.10.1-0.2
Pavlov. Cond. magazine entry number0.30.40.5-0.6-0.6-0.7-0.70.7-0.7-0.70.7-0.6
Pavlov. Cond. intertrial magazine entries0.10.10.1-0.2-0.2-0.4-0.40.3-0.3-0.40.3-0.2
Pavlov. Cond. lever-magazine prob. diff.0.20.20.30.40.40.50.5-0.50.50.5-0.50.4
Pavlov. Cond. response bias0.10.20.20.40.40.40.4-0.40.40.4-0.40.3
Pavlov. Cond. lever latency0.40.50.6-0.8-0.8-0.7-0.70.7-0.7-0.70.8-0.6
Pavlov. Cond. magazine entry latency0.10.10.1-0.2-0.2-0.3-0.30.3-0.3-0.30.3-0.3
Pavlov. Cond. change in total contacts0.71.81.91.41.41.31.3-1.41.41.4-1.41.2
Pavlov. Cond. index score0.30.50.60.70.70.60.6-0.70.70.7-0.70.6
Pavlov. Cond. latency score0.20.30.40.60.60.50.5-0.60.60.6-0.60.4
Pavlov. Cond. lever contacts0.20.20.30.50.50.40.4-0.50.50.5-0.50.3
Pavlov. Cond. magazine entry number0.00.00.10.00.00.20.2-0.20.20.2-0.20.3
Pavlov. Cond. intertrial magazine entries3.67.88.2-2.8-2.8-2.8-2.82.8-2.8-2.82.8-2.9
Pavlov. Cond. lever-magazine prob. diff.0.40.60.70.80.80.70.7-0.80.80.8-0.80.6
Pavlov. Cond. response bias0.20.30.30.60.60.50.5-0.50.50.5-0.60.4
Time in closed arm before self-admin1.11.92.11.31.31.41.4-1.41.41.4-1.41.4
Time in closed arm after self-admin0.00.00.00.10.10.20.2-0.20.20.2-0.20.2
Time in open arm before self-admin0.00.00.00.10.1-0.1-0.10.0-0.0-0.00.0-0.0
Time in open arm after self-admin0.00.00.1-0.1-0.1-0.2-0.20.2-0.2-0.20.2-0.2
Bone: periosteal estimation0.00.10.20.10.10.30.3-0.30.30.3-0.30.5
Bone: periosteal perimeter0.00.10.20.20.20.20.2-0.20.20.2-0.30.4
Bone: post-yield work0.10.20.3-0.6-0.6-0.4-0.40.5-0.5-0.40.5-0.5
Progressive ratio test 1 active lever presses0.10.10.10.30.30.30.3-0.30.30.3-0.30.2
Progressive ratio test 1 breakpoint0.10.20.20.40.40.40.4-0.40.40.4-0.40.3
Progressive ratio test 1 inactive lever presses0.41.21.2-1.0-1.0-1.1-1.11.1-1.1-1.11.1-1.1
Progressive ratio test 2 active lever presses0.00.00.0-0.1-0.1-0.2-0.20.2-0.2-0.20.2-0.2
Progressive ratio test 2 breakpoint0.00.00.0-0.1-0.1-0.1-0.10.2-0.2-0.10.2-0.2
Progressive ratio test 2 inactive lever presses0.10.40.4-0.7-0.7-0.6-0.60.7-0.7-0.60.7-0.7
Incentive Sensitization - Responses0.10.30.3-0.5-0.5-0.6-0.60.6-0.6-0.60.6-0.6
Incentive Sensitization - Breakpoint0.20.40.4-0.6-0.6-0.7-0.70.7-0.7-0.70.7-0.7
Sum of active levers in priming session hrs 5-60.10.10.1-0.2-0.2-0.3-0.30.4-0.4-0.30.4-0.4
Progressive ratio0.00.00.10.30.30.20.2-0.10.10.1-0.10.1
Food seeking constrained by brief footshock2.12.62.81.71.71.71.7-1.61.61.6-1.51.5
Seeking ratio, punishment vs. effort0.40.91.10.90.90.90.9-1.01.01.0-1.00.9
Retroperitoneal fat weight0.10.40.5-0.6-0.6-0.6-0.60.7-0.7-0.60.7-0.3
Reaction time number correct0.30.91.00.90.91.01.0-1.01.01.0-1.00.8
Reaction time mean minus median0.00.10.20.50.50.10.1-0.40.40.4-0.40.5
Reaction time mean minus median AUC0.00.10.10.40.40.00.0-0.30.30.3-0.30.3
Reaction time num false alarms0.10.10.20.30.30.20.2-0.40.40.4-0.40.1
Reaction time num false alarms AUC0.00.10.10.30.30.20.2-0.30.30.3-0.3-0.0
Reaction time trials correct on left0.30.91.00.90.91.01.0-1.01.01.0-1.00.8
Reaction time trials on left0.20.70.80.80.80.90.9-0.90.90.9-0.90.6
Reaction time mean0.10.20.30.50.50.30.3-0.40.40.4-0.40.3
Reaction time mean AUC0.20.40.60.70.70.50.5-0.60.60.6-0.60.5
Median of all reaction times0.10.10.20.50.50.30.3-0.40.40.4-0.40.2
Reaction time omissions1.62.63.0-1.5-1.5-1.7-1.71.6-1.6-1.61.6-1.7
Reaction time false alarm rate0.10.10.2-0.2-0.2-0.4-0.40.3-0.3-0.30.2-0.4
Reaction time premature initiation rate1.72.63.11.81.81.61.6-1.61.61.6-1.61.3
Reaction time premature initiations1.23.74.12.02.02.02.0-2.02.02.0-1.91.5
Std. dev. reaction times0.00.10.30.50.50.10.1-0.40.40.4-0.40.3
Reaction time trials completed0.20.70.80.80.80.90.9-0.90.90.9-0.90.6
Reaction time trials AUC0.20.60.70.70.70.80.8-0.80.80.8-0.80.6
Run reversals in cocaine runway, females2.83.13.3-1.8-1.8-1.7-1.71.8-1.8-1.81.8-1.8
Run reversals in cocaine runway, males1.82.02.01.41.41.41.4-1.41.41.4-1.41.4
Latency to leave start box in cocaine runway0.40.50.60.70.70.60.6-0.70.70.8-0.70.7
Latency to leave start box in cocaine runway, F1.21.51.61.21.21.21.2-1.31.31.3-1.31.3
Latency to leave start box in cocaine runway, M0.10.10.1-0.3-0.3-0.3-0.30.3-0.3-0.30.3-0.3
Std. dev. time between licks in bursts1.01.82.8-1.3-1.3-1.3-1.31.3-1.3-1.31.2-1.7
Total sessions with >9 infusions0.00.00.10.00.00.20.2-0.20.20.2-0.20.2
Short access day 1 total inactive lever presses0.10.10.1-0.3-0.3-0.4-0.40.4-0.4-0.40.3-0.3
Short access day 10 total inactive lever presses0.00.20.2-0.3-0.3-0.5-0.50.5-0.5-0.50.5-0.5
Short access day 1 total infusions0.00.10.10.10.10.30.3-0.30.20.3-0.20.2
Short access day 10 total infusions0.20.40.40.40.40.60.6-0.60.60.6-0.60.6
Short access total infusions0.00.00.10.00.00.20.2-0.20.20.2-0.20.2
Short access day 1 locomotion0.61.11.11.01.01.01.0-1.01.01.0-1.01.1
Short access day 10 total locomotion0.00.00.10.20.2-0.1-0.10.0-0.0-0.1-0.00.0
Short access total locomotion0.10.10.20.40.40.40.4-0.40.40.4-0.40.4
One hour access (0.3 mA shock)0.60.80.8-0.9-0.9-0.9-0.90.9-0.9-0.90.9-0.8
Compulsive drug intake0.40.60.8-0.7-0.7-0.9-0.90.8-0.8-0.90.8-0.8
One hour access (shock baseline)0.00.00.0-0.1-0.10.00.00.0-0.00.00.0-0.0
Social response proportion0.10.10.30.30.30.40.4-0.30.30.4-0.30.5
Social responses1.01.31.4-1.1-1.1-1.1-1.11.2-1.2-1.21.2-0.9
Social time0.20.40.5-0.7-0.7-0.6-0.60.6-0.6-0.60.6-0.5
Soleus weight1.23.53.71.91.91.91.9-1.91.91.9-1.91.6
Bone: stiffness0.61.11.50.90.91.11.1-1.01.11.1-1.11.2
Tibialis anterior weight8.228.429.35.45.45.35.3-5.35.35.3-5.35.3
Time to tail flick, vehicle, before self-admin0.91.11.1-1.0-1.0-1.0-1.01.0-1.0-1.01.0-1.1
Time to tail flick, vehicle, after self-admin0.91.82.21.21.21.51.5-1.41.41.4-1.31.3
Time to tail flick, test, before self-admin2.63.03.1-1.7-1.7-1.8-1.81.8-1.8-1.81.7-1.7
Time to tail flick, test, after self-admin2.32.42.7-1.5-1.5-1.6-1.61.6-1.6-1.61.6-1.6
Delta time to tail flick, vehicle, before/after SA0.30.30.40.50.50.60.6-0.50.50.5-0.50.5
Delta time to tail flick, test, before/after SA0.00.00.0-0.1-0.1-0.1-0.10.1-0.1-0.10.1-0.2
Tibia length1.23.34.2-2.0-2.0-1.8-1.81.8-1.8-1.81.7-1.5
Ambulatory time before self-admin0.10.40.40.60.60.60.6-0.60.60.6-0.60.6
Ambulatory time after self-admin3.96.36.82.62.62.52.5-2.52.52.5-2.52.5
Bone: tissue strength0.00.00.1-0.2-0.2-0.2-0.20.2-0.2-0.20.2-0.0
Total heroin consumption0.60.70.80.80.80.90.9-0.80.80.8-0.80.8
Bone: trabecular number1.93.53.6-1.9-1.9-1.9-1.91.9-1.9-1.91.9-1.8
Bone: trabecular spacing2.13.13.11.81.81.81.8-1.71.71.7-1.71.8
Bone: trabecular thickness1.11.51.6-1.3-1.3-1.2-1.21.2-1.2-1.21.2-1.2
Bone: trabecular tissue density1.11.92.01.31.31.41.4-1.41.41.4-1.41.4
Water consumed over 24 hours0.81.61.71.21.21.31.3-1.31.31.3-1.31.3
Number of responses in last shaping day0.50.60.70.70.70.80.8-0.80.80.8-0.80.8