Hub : Genes

Tnfrsf10b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression Tnfrsf10b 0.43 0.28 3.1e-13 0.29 0.3 0.3 0.3 7.0e-13 2.4e-13 1.3e-13 2.9e-13
2 LHb gene expression Tnfrsf10b 0.38 0.25 2.9e-06 0.09 0.16 0.1 0.1 3.3e-03 9.8e-05 3.0e-03 2.4e-03
3 OFC gene expression Tnfrsf10b 0.39 0.24 8.3e-06 0.09 0.16 0.12 0.11 4.1e-03 1.5e-04 1.1e-03 1.2e-03
4 Liver gene expression Tnfrsf10b 0.1 0.09 6.9e-10 0.08 0.08 0.08 0.08 1.9e-09 2.3e-09 2.1e-09 2.4e-09
5 Adipose gene expression Tnfrsf10b 0.18 0.14 0.0e+00 0.16 0.15 0.15 0.15 5.5e-17 1.2e-16 1.7e-16 8.6e-17
6 Eye gene expression Tnfrsf10b 0.31 0.23 2.7e-03 0.11 0.1 0.1 0.09 9.4e-03 1.5e-02 1.3e-02 1.7e-02
7 NAcc gene expression Tnfrsf10b 0.12 0.11 2.3e-10 0.09 0.07 0.08 0.08 6.8e-11 1.2e-08 4.3e-09 3.5e-09
8 PL gene expression Tnfrsf10b 0.11 0.1 2.1e-09 0.08 0.08 0.07 0.07 3.4e-09 7.2e-09 3.0e-08 1.2e-08
9 Brain mRNA stability Tnfrsf10b 0.03 0.03 6.6e-03 0.01 0.02 0 0.01 1.9e-02 6.0e-03 9.1e-02 4.1e-02
10 Brain gene expression Tnfrsf10b 0.23 0.17 0.0e+00 0.21 0.21 0.2 0.21 5.4e-19 2.3e-19 5.8e-18 7.4e-19

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density1.52.53.01.7-1.6-1.6-1.71.61.61.51.5-1.6-1.6
Area under the delay curve0.00.00.1-0.20.20.20.3-0.2-0.2-0.2-0.20.20.2
BMI with tail0.41.41.5-1.21.21.21.2-1.1-1.1-1.2-1.21.21.2
BMI without tail0.81.61.81.3-1.2-1.2-1.31.31.31.31.3-1.2-1.2
Body weight0.41.72.0-1.41.31.31.3-1.2-1.2-1.4-1.41.31.3
Weight adjusted by age1.92.12.2-1.51.41.41.4-1.5-1.5-1.4-1.41.41.4
Bone surface0.61.11.21.1-1.0-1.0-1.11.11.11.01.0-1.0-1.0
Bone volume0.81.31.51.2-1.1-1.1-1.21.11.11.11.1-1.1-1.1
Breakpoint value in progressive ratio session0.00.00.1-0.20.20.20.2-0.3-0.3-0.2-0.20.20.2
Number of licking bursts0.00.00.0-0.10.10.10.1-0.0-0.0-0.1-0.10.10.1
Context. condit. distance diff. score0.91.01.11.1-1.0-1.0-1.01.01.01.01.0-1.0-1.0
Locomotion velocity, session 10.10.20.2-0.40.40.40.4-0.4-0.4-0.4-0.40.40.4
Locomotion distance, session 10.00.00.00.1-0.1-0.1-0.00.00.00.20.2-0.1-0.1
Locomotion velocity, session 20.00.10.10.3-0.2-0.2-0.20.30.30.20.2-0.2-0.2
Locomotion distance, session 20.00.00.00.2-0.2-0.2-0.20.20.20.20.2-0.2-0.2
Locomotion velocity, session 30.50.50.6-0.80.70.70.8-0.8-0.8-0.7-0.70.70.7
Locomotion distance, session 30.00.00.00.1-0.1-0.1-0.10.10.10.20.2-0.1-0.1
Stereotopy head waving bouts, day 30.70.81.0-0.90.90.91.0-1.0-1.0-0.8-0.80.90.9
Stereotopy head waving duration, day 32.73.23.4-1.81.81.81.8-1.8-1.8-1.7-1.71.81.8
Locomotion velocity, session 74.54.95.22.3-2.2-2.2-2.22.22.22.32.3-2.2-2.2
Locomotion distance, session 73.54.44.62.1-2.1-2.1-2.12.12.12.12.1-2.1-2.1
Stereotopy head waving bouts, day 71.71.92.0-1.41.41.41.3-1.4-1.4-1.4-1.41.41.4
Stereotopy head waving duration, day 72.53.03.1-1.81.71.71.6-1.7-1.7-1.8-1.81.71.7
Locomotion velocity, session 80.00.00.00.1-0.1-0.1-0.10.10.10.10.1-0.1-0.1
Locomotion distance, session 80.60.91.01.0-1.0-1.0-0.91.01.01.01.0-1.0-1.0
Degree of sensitization distance4.94.95.22.3-2.2-2.2-2.22.32.32.22.2-2.2-2.2
Degree of sensitization stereotypy1.11.21.3-1.11.11.11.0-1.1-1.1-1.2-1.21.11.1
Conditioned locomotion0.00.00.00.2-0.2-0.2-0.10.20.20.20.2-0.2-0.2
Cocaine response after cond. corrected0.20.30.3-0.50.50.50.5-0.5-0.5-0.5-0.50.50.5
Cocaine response after cond. not corrected0.20.20.2-0.40.40.40.4-0.4-0.4-0.4-0.40.40.4
Cocaine response before conditioning0.10.20.20.4-0.4-0.4-0.50.40.40.40.4-0.4-0.4
Saline control response0.20.30.30.5-0.5-0.5-0.50.40.40.50.5-0.5-0.5
Bone: connectivity density2.94.65.12.2-2.1-2.1-2.32.22.22.12.1-2.1-2.1
Bone: cortical apparent density0.00.00.00.2-0.2-0.2-0.10.10.10.20.2-0.2-0.2
Bone: cortical area0.00.00.00.1-0.1-0.1-0.10.10.10.10.1-0.1-0.1
Bone: cortical porosity1.41.51.6-1.31.21.21.2-1.2-1.2-1.3-1.31.21.2
Bone: cortical porosity0.60.60.6-0.80.80.80.7-0.8-0.8-0.8-0.80.80.8
Bone: cortical thickness0.00.00.00.2-0.2-0.2-0.20.20.20.20.2-0.2-0.2
Bone: cortical thickness0.00.00.00.2-0.2-0.2-0.20.20.20.20.2-0.2-0.2
Bone: cortical tissue density0.00.00.00.2-0.2-0.2-0.10.10.10.20.2-0.2-0.2
Condit. Reinf. active minus inactive responses0.50.60.7-0.80.70.70.9-0.9-0.9-0.6-0.60.70.7
Condit. Reinf. active-inactive response ratio2.42.62.9-1.71.61.61.7-1.7-1.7-1.5-1.51.51.5
Condit. Reinf. active responses0.00.00.0-0.10.00.00.1-0.1-0.10.00.00.00.0
Condit. Reinf. inactive responses2.93.53.71.9-1.9-1.9-1.91.91.91.81.8-1.8-1.8
Incentive salience index mean0.81.01.1-1.01.01.01.1-1.1-1.1-0.9-0.90.90.9
Condit. Reinf. lever presses0.30.30.4-0.60.60.60.6-0.6-0.6-0.5-0.50.60.6
Condit. Reinf. active minus inactive responses0.30.40.40.6-0.6-0.6-0.60.70.70.60.6-0.6-0.6
Condit. Reinf. active-inactive response ratio0.10.10.1-0.40.40.40.3-0.4-0.4-0.4-0.40.40.4
Condit. Reinf. active responses0.91.21.41.1-1.1-1.1-1.11.21.21.11.1-1.1-1.1
Condit. Reinf. inactive responses2.32.93.01.7-1.7-1.7-1.61.71.71.71.7-1.7-1.7
Condit. Reinf. lever presses0.10.10.10.3-0.3-0.3-0.30.30.30.30.3-0.3-0.3
Condit. Reinf. lever reinforcers received0.60.80.90.9-0.9-0.9-0.91.01.00.90.9-0.9-0.9
Conditioned reinforcement - actives2.72.72.91.7-1.7-1.7-1.61.61.61.71.7-1.6-1.6
Conditioned reinforcement - inactives3.03.43.71.9-1.9-1.9-1.91.81.81.81.8-1.8-1.8
Conditioned locomotion1.11.31.51.2-1.1-1.1-1.21.21.21.11.1-1.1-1.1
Patch foraging indifference point 0 sec2.23.53.61.9-1.9-1.9-1.91.91.91.81.8-1.9-1.9
Patch foraging indifference point AUC0.60.70.9-0.80.80.80.9-0.8-0.8-0.7-0.70.80.8
Delay disc. indifference point, 0s delay0.30.30.50.6-0.6-0.6-0.50.50.50.70.7-0.6-0.6
Delay disc. indifference point, 16s delay0.20.20.20.5-0.5-0.5-0.40.40.40.40.4-0.5-0.5
Delay disc. indifference point, 2s delay1.51.61.7-1.31.31.31.3-1.3-1.3-1.3-1.31.31.3
Delay disc. indifference point, 24s delay0.30.20.3-0.50.50.50.5-0.5-0.5-0.5-0.50.50.5
Delay disc. indifference point, 4s delay1.61.71.8-1.31.31.31.4-1.3-1.3-1.2-1.21.31.3
Delay disc. indifference point, 8s delay0.00.00.00.2-0.1-0.1-0.10.10.10.20.2-0.1-0.1
Indifference point function ln k0.00.00.00.2-0.1-0.1-0.20.20.20.10.1-0.1-0.1
Indifference point function log k0.00.00.00.2-0.1-0.1-0.20.20.20.10.1-0.1-0.1
Patch foraging total patch changes 0 sec1.82.93.01.7-1.7-1.7-1.71.71.71.61.6-1.7-1.7
Patch foraging total patch changes 12 sec0.70.91.11.0-1.0-1.0-0.91.01.01.01.0-1.0-1.0
Patch foraging total patch changes 18 sec1.92.42.61.6-1.6-1.6-1.41.51.51.61.6-1.6-1.6
Patch foraging total patch changes 24 sec0.00.00.00.0-0.1-0.1-0.00.00.00.00.0-0.1-0.1
Patch foraging total patch changes 6 sec0.30.50.50.7-0.7-0.7-0.70.60.60.70.7-0.7-0.7
Patch foraging time to switch 0 sec0.71.11.21.1-1.1-1.1-1.10.90.91.01.0-1.1-1.1
Patch foraging water rate 0 sec0.30.50.6-0.70.70.70.7-0.5-0.5-0.8-0.80.70.7
Patch foraging water rate 12 sec0.60.81.0-0.91.01.00.8-0.8-0.8-1.0-1.01.01.0
Patch foraging water rate 18 sec2.83.84.2-2.02.02.01.8-1.8-1.8-2.0-2.02.02.0
Patch foraging water rate 24 sec0.00.10.1-0.20.30.30.0-0.0-0.0-0.4-0.40.30.3
Patch foraging water rate 6 sec2.03.03.2-1.81.81.81.8-1.6-1.6-1.7-1.71.81.8
Seeking ratio, delayed vs. immediate footshock1.11.31.61.2-1.1-1.1-1.21.31.31.01.0-1.1-1.1
Distance traveled before self-admin1.11.11.3-1.01.01.01.0-1.1-1.1-1.1-1.11.01.0
Distance traveled after self-admin2.22.42.8-1.61.61.61.7-1.4-1.4-1.6-1.61.61.6
Extensor digitorum longus weight12.850.453.1-7.37.17.17.1-7.1-7.1-7.1-7.17.07.0
Bone: elastic displacement0.50.60.70.8-0.8-0.8-0.70.70.70.80.8-0.8-0.8
Bone: elastic work0.30.40.40.6-0.6-0.6-0.50.60.60.60.6-0.6-0.6
Bone: endosteal estimation0.10.20.3-0.50.50.50.4-0.4-0.4-0.5-0.50.50.5
Bone: endosteal perimeter0.10.10.2-0.30.40.40.3-0.3-0.3-0.4-0.40.40.4
Epididymis fat weight2.35.25.52.3-2.3-2.3-2.32.32.32.32.3-2.3-2.3
Delta time in closed arm before/after self-admin2.12.12.41.5-1.4-1.4-1.41.41.41.51.5-1.4-1.4
Delta time in open arm before/after self-admin0.10.10.20.2-0.2-0.2-0.30.40.40.00.0-0.2-0.2
Diff in mean of infusions in LGA sessions2.83.13.8-1.71.71.71.7-2.0-2.0-1.7-1.71.71.7
Delay discount exponential model param0.20.20.30.5-0.5-0.5-0.60.50.50.50.5-0.5-0.5
Extinction: sum of active levers before priming2.82.73.31.6-1.6-1.6-1.41.81.81.71.7-1.6-1.6
Active lever presses in extinction session 60.30.30.30.6-0.6-0.6-0.50.30.30.60.6-0.6-0.6
Bone: final force0.10.20.2-0.50.40.40.5-0.4-0.4-0.4-0.40.40.4
Bone: final moment0.10.10.1-0.40.40.40.4-0.4-0.4-0.4-0.40.40.4
Food consumed during 24 hour testing period0.20.30.40.5-0.5-0.5-0.50.60.60.50.5-0.5-0.5
Glucose0.00.00.00.1-0.1-0.1-0.10.10.10.20.2-0.1-0.1
Heart weight0.00.00.10.2-0.1-0.1-0.20.20.20.00.0-0.1-0.1
Delay discount hyperbolic model param0.60.60.70.8-0.8-0.8-0.80.80.80.70.7-0.8-0.8
Intermittent access intake day 1-15 change2.22.22.61.5-1.5-1.5-1.51.61.61.41.4-1.4-1.4
Intermittent access intake escalation1.51.51.81.2-1.2-1.2-1.21.31.31.11.1-1.2-1.2
Intermittent access intake escalation 20.50.50.70.7-0.6-0.6-0.80.80.80.60.6-0.6-0.6
Intermitt. access day 1 inactive lever presses0.10.10.10.3-0.3-0.3-0.20.30.30.30.3-0.3-0.3
Intermitt. access day 15 inactive lever presses0.00.00.00.1-0.1-0.1-0.2-0.2-0.20.10.1-0.1-0.1
Intermitt. access escalation Index0.50.50.6-0.70.70.70.6-0.8-0.8-0.6-0.60.60.6
Intermittent access day 1 total infusions0.00.00.10.2-0.2-0.2-0.30.10.10.20.2-0.2-0.2
Intermittent access day 15 total infusions1.01.11.41.1-1.1-1.1-1.21.11.11.01.0-1.0-1.0
Intermittent access terminal intake (last 3 days)0.20.30.40.5-0.5-0.5-0.60.60.60.40.4-0.5-0.5
Intermittent access total infusions0.50.50.70.7-0.7-0.7-0.80.70.70.70.7-0.7-0.7
Intermittent access day 1 locomotion0.40.40.60.6-0.6-0.6-0.70.60.60.60.6-0.6-0.6
Intermittent access day 15 total locomotion1.61.72.11.3-1.3-1.3-1.21.51.51.31.3-1.2-1.2
Intermittent access total locomotion0.50.60.70.8-0.7-0.7-0.90.80.80.70.7-0.7-0.7
Intermittent access standard deviation1.31.41.71.2-1.2-1.2-1.31.31.31.11.1-1.1-1.1
Left kidney weight0.20.71.1-0.80.90.90.6-0.6-0.6-1.1-1.10.90.9
Right kidney weight0.10.40.60.6-0.6-0.6-0.80.80.80.40.4-0.6-0.6
Cocaine induced anxiety0.10.20.2-0.40.40.40.4-0.5-0.5-0.4-0.40.40.4
Post-drug Anxiety0.50.50.60.7-0.7-0.7-0.70.70.70.70.7-0.7-0.7
Baseline Anxiety0.80.91.00.9-0.9-0.9-0.91.01.00.90.9-0.9-0.9
Tail length0.92.83.01.7-1.6-1.6-1.71.71.71.71.7-1.6-1.6
Length with tail0.10.30.4-0.50.50.50.5-0.4-0.4-0.6-0.60.50.5
Length without tail3.98.69.3-3.02.92.93.0-2.8-2.8-3.1-3.12.92.9
Times rat made contact with spout0.40.50.60.8-0.7-0.7-0.80.70.70.70.7-0.7-0.7
Lifetime Intake0.40.50.70.7-0.7-0.7-0.80.60.60.70.7-0.7-0.7
Liver weight, left2.33.63.8-1.91.91.91.9-1.8-1.8-1.9-1.91.91.9
Liver weight, right0.71.21.3-1.11.11.11.1-1.1-1.1-1.1-1.11.11.1
Locomotor activity1.42.32.5-1.61.51.51.4-1.5-1.5-1.6-1.61.51.5
Locomotor testing distance0.00.00.00.0-0.0-0.0-0.10.10.10.00.0-0.0-0.0
Locomotor testing rearing0.20.40.40.6-0.6-0.6-0.70.60.60.60.6-0.6-0.6
Locomotion in novel chamber0.10.20.20.4-0.4-0.4-0.50.40.40.40.4-0.4-0.4
Locomotion in novel chamber post-restriction0.60.80.9-0.90.90.90.8-0.8-0.8-0.9-0.90.90.9
Fecal boli incidents, locomotor time 10.80.91.0-1.01.01.01.0-0.9-0.9-0.9-0.91.01.0
Change in fecal boli incidents, locomotor task0.10.10.2-0.30.30.30.2-0.4-0.4-0.3-0.30.30.3
Time >=10cm from walls, locomotor time 10.70.80.90.9-0.9-0.9-0.80.70.71.01.0-0.9-0.9
Bouts of movement, locomotor time 15.05.45.8-2.42.42.42.3-2.4-2.4-2.2-2.22.42.4
Total resting periods, locomotor time 14.95.45.8-2.42.42.42.3-2.4-2.4-2.2-2.22.32.3
Rest time, locomotor task time 13.23.53.8-1.91.91.91.9-2.0-2.0-1.8-1.81.91.9
Distance moved, locomotor task time 13.13.43.71.9-1.8-1.8-1.81.91.91.71.7-1.8-1.8
Vertical activity count, locomotor time 11.11.21.31.1-1.1-1.1-1.11.11.10.90.9-1.1-1.1
Time >=10cm from walls, locomotor time 20.40.40.5-0.60.60.60.6-0.6-0.6-0.7-0.70.60.6
Bouts of movement, locomotor time 23.63.94.2-2.02.02.01.8-2.0-2.0-1.9-1.92.02.0
Total resting periods, locomotor time 24.24.54.7-2.22.22.12.0-2.1-2.1-2.1-2.12.12.1
Rest time, locomotor task time 21.01.11.4-1.01.01.01.0-1.1-1.1-1.2-1.21.01.0
Distance moved, locomotor task time 22.83.23.71.8-1.8-1.8-1.71.91.91.71.7-1.7-1.7
Vertical activity count, locomotor time 20.30.40.40.6-0.6-0.6-0.50.60.60.60.6-0.6-0.6
Light reinforcement 13.46.26.82.6-2.5-2.5-2.62.42.42.52.5-2.5-2.5
Light reinforcement 21.31.72.01.4-1.4-1.4-1.41.11.11.31.3-1.3-1.3
Bone: marrow area0.10.10.2-0.30.40.40.3-0.3-0.3-0.4-0.40.40.4
Bone: maximum diameter0.30.60.6-0.80.80.80.7-0.7-0.7-0.8-0.80.80.8
Bone: maximum force0.20.40.4-0.60.60.60.6-0.6-0.6-0.6-0.60.60.6
Bone: maximum moment0.10.20.2-0.40.50.50.4-0.5-0.5-0.4-0.40.50.5
Mean time between licks in bursts2.02.82.91.7-1.7-1.7-1.71.71.71.71.7-1.7-1.7
Mean num. licks in bursts0.40.50.50.7-0.7-0.7-0.70.60.60.70.7-0.7-0.7
Cd content in liver0.30.30.40.6-0.6-0.6-0.50.40.40.60.6-0.6-0.6
Co content in liver4.04.64.9-2.22.22.22.2-2.1-2.1-2.1-2.12.12.1
Cu content in liver0.50.70.7-0.80.80.80.8-0.9-0.9-0.8-0.80.80.8
Fe content in liver2.22.62.91.7-1.6-1.6-1.71.61.61.61.6-1.6-1.6
K content in liver0.60.60.60.8-0.8-0.8-0.80.70.70.80.8-0.8-0.8
Mg content in liver1.21.31.41.2-1.1-1.1-1.11.11.11.11.1-1.1-1.1
Mn content in liver2.12.42.51.6-1.5-1.5-1.51.51.51.51.5-1.5-1.5
Na content in liver0.70.70.8-0.90.80.80.8-0.9-0.9-0.8-0.80.80.8
Rb content in liver0.30.30.40.6-0.6-0.6-0.70.60.60.50.5-0.6-0.6
Se content in liver0.91.11.21.1-1.1-1.1-1.11.01.01.01.0-1.0-1.0
Sr content in liver0.40.40.50.7-0.7-0.7-0.60.60.60.70.7-0.6-0.6
Zn content in liver1.01.11.2-1.11.01.01.1-1.1-1.1-1.0-1.01.01.0
Bone: minimum diameter0.10.20.3-0.50.50.50.4-0.4-0.4-0.5-0.50.50.5
Time in familiar zone, hab. session 10.00.00.0-0.20.10.10.1-0.1-0.1-0.2-0.20.10.1
Time in novel zone, hab. session 11.31.31.4-1.21.11.11.2-1.2-1.2-1.1-1.11.11.1
Total zone transitions, hab. session 10.20.30.4-0.60.50.50.6-0.6-0.6-0.5-0.50.50.5
Total locomotion distance, hab. session 10.00.00.00.0-0.0-0.00.1-0.0-0.00.10.1-0.0-0.0
Locomotion velocity, hab. session 10.10.10.20.3-0.4-0.4-0.30.30.30.40.4-0.4-0.4
Time in familiar zone, hab. session 22.02.12.2-1.51.41.41.4-1.4-1.4-1.4-1.41.41.4
Time in novel zone, hab. session 20.80.70.80.9-0.9-0.9-0.80.80.80.90.9-0.9-0.9
Total zone transitions, hab. session 21.51.92.0-1.41.41.41.4-1.4-1.4-1.3-1.31.31.3
Total locomotion distance, hab. session 20.20.30.4-0.60.60.60.6-0.6-0.6-0.5-0.50.50.5
Locomotion velocity, hab. session 20.60.80.8-0.90.90.90.9-0.9-0.9-0.8-0.80.90.8
Novel to familiar place preference ratio1.61.61.71.3-1.3-1.3-1.31.21.21.31.3-1.3-1.3
Novelty place preference1.21.21.31.1-1.1-1.1-1.11.11.11.11.1-1.1-1.1
Time in novel zone, NPP test0.60.60.70.8-0.8-0.8-0.80.80.80.80.8-0.8-0.8
Total zone transitions, NPP test0.20.20.30.5-0.5-0.5-0.40.40.40.50.5-0.5-0.5
Total locomotion distance, NPP test2.63.63.71.9-1.9-1.9-1.81.81.81.91.9-1.9-1.9
Locomotion velocity, NPP test2.53.53.71.9-1.9-1.9-1.81.81.81.91.9-1.9-1.9
Intraocular pressure0.50.70.80.8-0.9-0.9-0.70.80.80.90.9-0.9-0.9
Delta distance traveled before/after self-admin2.32.42.9-1.61.61.61.7-1.3-1.3-1.6-1.61.61.6
Delta ambulatory time before/after self-admin2.12.32.6-1.61.61.61.6-1.3-1.3-1.6-1.61.61.6
Parametrial fat weight3.67.07.32.7-2.6-2.6-2.72.72.72.62.6-2.6-2.6
Pavlov. Cond. lever latency0.00.00.0-0.00.00.00.1-0.0-0.0-0.0-0.00.00.0
Pavlov. Cond. magazine entry latency0.00.00.10.2-0.2-0.2-0.20.20.20.20.2-0.2-0.2
Pavlov. Cond. change in total contacts1.01.11.1-1.01.01.01.0-1.0-1.0-1.0-1.01.01.0
Pavlov. Cond. index score0.10.10.1-0.30.20.20.2-0.3-0.3-0.3-0.30.20.2
Pavlov. Cond. latency score0.00.00.0-0.10.10.10.1-0.1-0.1-0.1-0.10.10.1
Pavlov. Cond. lever contacts0.00.00.00.1-0.1-0.1-0.10.10.10.10.1-0.1-0.1
Pavlov. Cond. magazine entry number0.40.50.60.8-0.7-0.7-0.70.80.80.70.7-0.7-0.7
Pavlov. Cond. intertrial magazine entries0.10.10.10.3-0.3-0.3-0.30.30.30.30.3-0.3-0.3
Pavlov. Cond. lever-magazine prob. diff.0.10.20.2-0.40.40.40.4-0.4-0.4-0.4-0.40.40.4
Pavlov. Cond. response bias0.10.20.2-0.40.40.40.3-0.4-0.4-0.4-0.40.40.4
Pavlov. Cond. lever latency0.40.50.50.7-0.7-0.7-0.70.70.70.70.7-0.7-0.7
Pavlov. Cond. magazine entry latency0.10.10.10.3-0.3-0.3-0.20.30.30.30.3-0.3-0.3
Pavlov. Cond. change in total contacts1.62.22.4-1.51.51.51.5-1.5-1.5-1.5-1.51.51.5
Pavlov. Cond. index score0.50.60.7-0.80.80.80.8-0.8-0.8-0.8-0.80.80.8
Pavlov. Cond. latency score0.30.40.4-0.70.60.60.6-0.6-0.6-0.6-0.60.60.6
Pavlov. Cond. lever contacts0.40.50.5-0.70.70.70.7-0.7-0.7-0.7-0.70.70.7
Pavlov. Cond. magazine entry number0.00.10.1-0.20.20.20.2-0.2-0.2-0.2-0.20.20.2
Pavlov. Cond. intertrial magazine entries6.28.08.42.9-2.8-2.8-2.82.92.92.82.8-2.8-2.8
Pavlov. Cond. lever-magazine prob. diff.0.60.80.8-0.90.90.90.9-0.9-0.9-0.9-0.90.90.9
Pavlov. Cond. response bias0.50.60.7-0.80.80.80.8-0.8-0.8-0.8-0.80.80.8
Time in closed arm before self-admin1.92.12.4-1.51.51.51.4-1.4-1.4-1.6-1.61.51.5
Time in closed arm after self-admin0.60.60.7-0.80.80.80.7-0.8-0.8-0.8-0.80.80.8
Time in open arm before self-admin0.20.20.4-0.40.30.30.4-0.6-0.6-0.2-0.20.30.3
Time in open arm after self-admin0.10.10.20.3-0.3-0.3-0.20.40.40.30.3-0.3-0.3
Bone: periosteal estimation0.00.10.1-0.20.20.20.2-0.2-0.2-0.3-0.30.20.3
Bone: periosteal perimeter0.00.00.0-0.10.10.10.0-0.0-0.0-0.1-0.10.10.1
Bone: post-yield work0.20.20.30.5-0.5-0.5-0.60.50.50.40.4-0.5-0.5
Progressive ratio test 1 active lever presses0.20.20.3-0.50.40.40.4-0.6-0.6-0.5-0.50.40.4
Progressive ratio test 1 breakpoint0.10.10.2-0.30.30.30.2-0.4-0.4-0.3-0.30.30.3
Progressive ratio test 1 inactive lever presses1.51.71.91.4-1.3-1.3-1.41.11.11.31.3-1.3-1.3
Progressive ratio test 2 active lever presses0.20.20.20.5-0.5-0.5-0.40.50.50.50.5-0.5-0.5
Progressive ratio test 2 breakpoint0.20.30.30.5-0.5-0.5-0.50.50.50.50.5-0.5-0.5
Progressive ratio test 2 inactive lever presses0.40.40.50.7-0.7-0.7-0.60.60.60.70.7-0.7-0.7
Incentive Sensitization - Responses1.01.01.21.0-1.0-1.0-0.81.11.11.01.0-1.0-1.0
Incentive Sensitization - Breakpoint1.41.41.71.2-1.2-1.2-1.01.31.31.21.2-1.2-1.2
Sum of active levers in priming session hrs 5-60.10.10.10.2-0.2-0.2-0.10.10.10.40.4-0.2-0.2
Progressive ratio0.10.10.20.4-0.3-0.3-0.40.30.30.40.4-0.3-0.3
Food seeking constrained by brief footshock1.31.61.7-1.31.31.31.3-1.3-1.3-1.3-1.31.31.3
Seeking ratio, punishment vs. effort0.91.11.2-1.11.11.11.1-1.0-1.0-1.1-1.11.01.0
Retroperitoneal fat weight0.20.71.10.9-0.8-0.8-1.01.11.10.60.6-0.8-0.8
Reaction time number correct0.50.81.0-0.90.90.91.0-0.7-0.7-1.0-1.00.90.9
Reaction time mean minus median0.20.20.3-0.50.40.40.5-0.5-0.5-0.5-0.50.40.4
Reaction time mean minus median AUC0.10.20.2-0.40.40.40.4-0.5-0.5-0.4-0.40.40.4
Reaction time num false alarms0.00.00.1-0.20.20.20.10.00.0-0.4-0.40.20.2
Reaction time num false alarms AUC0.00.00.00.00.00.0-0.10.20.2-0.2-0.20.00.0
Reaction time trials correct on left0.50.81.0-0.90.90.91.0-0.7-0.7-1.0-1.00.90.9
Reaction time trials on left0.40.60.7-0.80.80.80.9-0.6-0.6-0.8-0.80.80.8
Reaction time mean0.20.30.4-0.50.50.50.6-0.7-0.7-0.4-0.40.50.5
Reaction time mean AUC0.40.50.7-0.70.70.70.8-0.8-0.8-0.6-0.60.70.7
Median of all reaction times0.10.10.2-0.30.30.30.4-0.4-0.4-0.3-0.30.30.3
Reaction time omissions2.12.93.11.7-1.7-1.7-1.71.61.61.71.7-1.7-1.7
Reaction time false alarm rate0.10.20.30.5-0.4-0.4-0.50.50.50.30.3-0.4-0.4
Reaction time premature initiation rate1.51.92.4-1.41.41.41.3-1.5-1.5-1.3-1.31.41.3
Reaction time premature initiations2.23.03.2-1.81.71.71.7-1.8-1.8-1.7-1.71.71.7
Std. dev. reaction times0.20.30.3-0.50.50.50.6-0.6-0.6-0.5-0.50.50.5
Reaction time trials completed0.40.60.7-0.80.80.80.9-0.6-0.6-0.8-0.80.80.8
Reaction time trials AUC0.40.50.7-0.70.70.70.8-0.6-0.6-0.8-0.80.70.7
Run reversals in cocaine runway, females4.14.04.22.1-2.0-2.0-2.02.02.02.12.1-2.0-2.0
Run reversals in cocaine runway, males2.52.42.5-1.61.61.61.5-1.5-1.5-1.5-1.51.51.5
Latency to leave start box in cocaine runway0.60.60.7-0.80.80.80.8-0.8-0.8-0.8-0.80.80.8
Latency to leave start box in cocaine runway, F1.41.61.7-1.31.21.21.3-1.2-1.2-1.3-1.31.21.2
Latency to leave start box in cocaine runway, M1.31.21.31.1-1.1-1.1-1.11.11.11.11.1-1.1-1.1
Std. dev. time between licks in bursts1.41.71.91.4-1.3-1.3-1.41.21.21.31.3-1.3-1.3
Total sessions with >9 infusions0.00.00.00.2-0.1-0.1-0.20.00.00.10.1-0.1-0.1
Short access day 1 total inactive lever presses0.50.60.60.8-0.8-0.8-0.80.70.70.80.8-0.8-0.8
Short access day 10 total inactive lever presses0.40.40.40.7-0.6-0.6-0.60.50.50.60.6-0.6-0.6
Short access day 1 total infusions0.10.10.2-0.30.30.30.2-0.4-0.4-0.3-0.30.30.3
Short access day 10 total infusions0.00.00.10.2-0.2-0.2-0.20.00.00.20.2-0.2-0.2
Short access total infusions0.20.20.30.5-0.5-0.5-0.60.30.30.50.5-0.5-0.5
Short access day 1 locomotion0.20.20.2-0.40.40.40.3-0.4-0.4-0.5-0.50.40.4
Short access day 10 total locomotion0.60.60.80.8-0.8-0.8-0.90.70.70.80.8-0.8-0.8
Short access total locomotion0.70.81.10.9-0.9-0.9-1.00.80.80.90.9-0.9-0.9
One hour access (0.3 mA shock)0.30.30.50.6-0.6-0.6-0.60.70.70.50.5-0.6-0.6
Compulsive drug intake0.00.00.0-0.10.10.10.20.10.1-0.1-0.10.10.1
One hour access (shock baseline)0.00.00.00.0-0.0-0.0-0.1-0.1-0.1-0.0-0.0-0.0-0.0
Social response proportion0.10.10.1-0.30.30.30.2-0.2-0.2-0.4-0.40.30.3
Social responses1.11.41.51.2-1.2-1.2-1.11.21.21.21.2-1.2-1.2
Social time0.30.50.60.7-0.7-0.7-0.80.70.70.60.6-0.7-0.7
Soleus weight0.92.83.1-1.81.71.71.7-1.5-1.5-1.7-1.71.71.7
Bone: stiffness0.60.90.9-0.90.90.90.9-0.9-0.9-1.0-1.00.90.9
Tibialis anterior weight8.227.929.5-5.45.35.35.3-5.2-5.2-5.3-5.35.35.3
Time to tail flick, vehicle, before self-admin0.80.80.91.0-0.9-0.9-0.90.80.80.80.8-0.9-0.9
Time to tail flick, vehicle, after self-admin2.02.22.9-1.51.41.41.3-1.7-1.7-1.4-1.41.41.4
Time to tail flick, test, before self-admin0.90.91.01.0-1.0-1.0-0.90.90.91.01.0-1.0-1.0
Time to tail flick, test, after self-admin3.33.43.71.9-1.9-1.9-1.91.81.81.81.8-1.8-1.8
Delta time to tail flick, vehicle, before/after SA0.40.40.4-0.60.60.60.5-0.7-0.7-0.5-0.50.60.6
Delta time to tail flick, test, before/after SA0.30.30.30.5-0.5-0.5-0.50.60.60.40.4-0.5-0.5
Tibia length1.23.43.71.9-1.9-1.9-1.91.81.81.81.8-1.8-1.8
Ambulatory time before self-admin0.60.70.8-0.90.80.80.9-0.8-0.8-0.8-0.80.80.8
Ambulatory time after self-admin3.64.04.4-2.12.02.02.1-1.8-1.8-2.0-2.02.02.0
Bone: tissue strength0.10.10.10.3-0.3-0.3-0.30.30.30.30.3-0.3-0.3
Total heroin consumption0.30.40.5-0.60.60.60.4-0.7-0.7-0.7-0.70.60.6
Bone: trabecular number2.74.24.72.1-2.1-2.0-2.22.12.12.02.0-2.0-2.0
Bone: trabecular spacing2.43.13.4-1.81.81.81.8-1.7-1.7-1.8-1.81.81.8
Bone: trabecular thickness1.31.51.71.3-1.2-1.2-1.31.21.21.21.2-1.2-1.2
Bone: trabecular tissue density1.41.92.2-1.41.41.41.4-1.5-1.5-1.3-1.31.41.4
Water consumed over 24 hours1.31.61.7-1.31.31.31.2-1.2-1.2-1.3-1.31.31.3
Number of responses in last shaping day0.00.00.1-0.10.10.10.1-0.3-0.3-0.0-0.00.10.1