Hub : Genes

LOC120102855

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	NAcc	gene expression	LOC120102855	0.03	0.03	3.9e-03	0.02	0.02	0.02	0.02	4.1e-03	5.3e-03	2.7e-03	2.6e-03
2	Liver	gene expression	LOC120102855	0.43	0.09	0.0e+00	0.46	0.48	0.47	0.48	2.3e-57	2.3e-59	2.4e-58	1.3e-59
3	Adipose	gene expression	LOC120102855	0.26	0.1	0.0e+00	0.15	0.17	0.13	0.15	5.0e-16	3.7e-18	2.7e-14	1.4e-16

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Bone: apparent density	0.6	1.0	2.1	-0.9	1.5	-0.1
Area under the delay curve	0.2	0.2	0.5	-0.1	-0.7	-0.4
BMI with tail	0.9	2.9	5.7	-1.7	2.4	-0.3
BMI without tail	3.3	6.8	9.9	-3.2	2.5	-2.1
Body weight	2.1	8.6	11.3	-3.4	3.1	-2.2
Weight adjusted by age	1.1	1.2	3.4	-0.3	-0.3	-1.9
Bone surface	0.9	1.6	2.8	-1.7	1.0	-1.0
Bone volume	0.6	1.0	1.6	-1.2	1.1	-0.5
Breakpoint value in progressive ratio session	1.1	1.3	2.3	-0.2	-1.2	-1.5
Number of licking bursts	4.8	5.7	10.2	-2.6	3.2	-0.6
Context. condit. distance diff. score	0.4	0.5	1.0	1.0	-0.4	0.6
Locomotion velocity, session 1	2.9	3.1	8.7	0.2	-0.7	-3.0
Locomotion distance, session 1	0.9	1.1	3.3	0.1	-0.2	-1.8
Locomotion velocity, session 2	1.0	1.2	2.5	-1.0	1.6	-0.2
Locomotion distance, session 2	1.1	1.5	3.0	-0.6	1.1	-1.7
Locomotion velocity, session 3	0.7	0.8	0.9	0.9	-0.9	-0.9
Locomotion distance, session 3	0.8	0.9	1.7	-0.8	0.6	-1.3
Stereotopy head waving bouts, day 3	0.5	0.6	1.0	-1.0	0.2	-0.9
Stereotopy head waving duration, day 3	0.3	0.3	0.8	-0.9	0.4	-0.2
Locomotion velocity, session 7	0.1	0.1	0.3	0.2	-0.5	0.3
Locomotion distance, session 7	0.2	0.3	0.8	0.9	-0.3	-0.3
Stereotopy head waving bouts, day 7	3.1	3.5	5.3	-2.2	2.3	-0.8
Stereotopy head waving duration, day 7	2.4	2.9	5.2	-2.3	1.8	-0.6
Locomotion velocity, session 8	0.6	0.7	1.8	0.4	-0.2	-1.3
Locomotion distance, session 8	0.5	0.7	1.2	0.9	-0.3	-1.1
Degree of sensitization distance	0.8	0.8	1.2	1.1	-0.7	0.8
Degree of sensitization stereotypy	1.8	2.0	3.0	-1.6	1.7	-0.4
Conditioned locomotion	0.4	0.5	0.7	0.4	-0.7	-0.8
Cocaine response after cond. corrected	1.0	1.1	1.9	0.5	-1.4	-1.0
Cocaine response after cond. not corrected	0.9	1.0	1.9	0.0	-1.1	-1.4
Cocaine response before conditioning	1.4	1.7	2.8	-1.7	1.5	-0.4
Saline control response	2.9	3.8	5.1	-2.3	1.5	-2.0
Bone: connectivity density	0.5	0.7	1.2	-1.1	1.0	0.1
Bone: cortical apparent density	0.5	0.7	1.9	-0.2	0.4	1.4
Bone: cortical area	2.9	4.4	6.5	-2.6	2.5	-0.6
Bone: cortical porosity	0.5	0.6	1.3	1.1	-0.2	0.6
Bone: cortical porosity	0.2	0.2	0.4	0.6	0.3	0.2
Bone: cortical thickness	1.3	2.1	4.0	-1.5	2.0	0.5
Bone: cortical thickness	0.2	0.2	0.4	0.3	0.3	0.7
Bone: cortical tissue density	0.5	0.6	1.7	-0.1	0.2	1.3
Condit. Reinf. active minus inactive responses	0.1	0.1	0.3	-0.1	0.5	-0.2
Condit. Reinf. active-inactive response ratio	1.1	1.2	1.9	1.4	-0.9	1.0
Condit. Reinf. active responses	1.9	2.3	3.2	-1.7	1.8	-1.0
Condit. Reinf. inactive responses	3.3	3.9	5.5	-2.4	2.3	-1.0
Incentive salience index mean	2.3	2.8	3.4	-1.7	1.9	-1.4
Condit. Reinf. lever presses	7.4	9.9	11.3	-3.4	3.2	-2.9
Condit. Reinf. active minus inactive responses	0.6	0.8	1.6	-1.3	0.8	-0.4
Condit. Reinf. active-inactive response ratio	0.0	0.0	0.1	0.1	0.2	0.3
Condit. Reinf. active responses	1.8	2.6	4.7	-2.2	1.5	-0.8
Condit. Reinf. inactive responses	3.0	3.7	6.7	-2.6	2.1	-0.5
Condit. Reinf. lever presses	2.0	2.7	5.2	-2.3	1.7	-0.0
Condit. Reinf. lever reinforcers received	2.1	2.9	5.4	-2.3	1.6	-0.9
Conditioned reinforcement - actives	0.2	0.2	0.3	-0.6	0.3	0.3
Conditioned reinforcement - inactives	0.0	0.0	0.0	0.2	-0.0	-0.2
Conditioned locomotion	0.4	0.5	1.4	1.2	0.0	0.4
Patch foraging indifference point 0 sec	1.8	2.9	8.2	-0.7	-0.5	-2.9
Patch foraging indifference point AUC	3.4	3.9	4.7	-2.2	2.2	-1.6
Delay disc. indifference point, 0s delay	0.5	0.6	1.1	1.0	-0.8	-0.1
Delay disc. indifference point, 16s delay	1.2	1.2	2.0	-0.6	-1.4	-1.1
Delay disc. indifference point, 2s delay	0.3	0.4	0.6	-0.4	0.8	0.6
Delay disc. indifference point, 24s delay	0.1	0.1	0.2	-0.5	-0.4	-0.1
Delay disc. indifference point, 4s delay	0.1	0.1	0.2	0.4	-0.3	0.3
Delay disc. indifference point, 8s delay	0.1	0.1	0.2	-0.5	0.2	-0.3
Indifference point function ln k	0.8	1.2	2.3	1.0	-1.5	0.4
Indifference point function log k	0.8	1.2	2.3	1.0	-1.5	0.4
Patch foraging total patch changes 0 sec	1.8	2.9	7.8	-0.9	0.1	-2.8
Patch foraging total patch changes 12 sec	0.8	1.0	1.3	-1.0	1.0	-1.1
Patch foraging total patch changes 18 sec	0.8	1.0	1.5	-1.2	0.0	-1.2
Patch foraging total patch changes 24 sec	2.0	2.5	3.5	-1.7	1.0	-1.9
Patch foraging total patch changes 6 sec	2.6	3.8	7.5	-1.8	0.9	-2.7
Patch foraging time to switch 0 sec	2.4	3.7	4.7	2.2	-1.5	2.0
Patch foraging water rate 0 sec	1.2	1.8	4.2	-0.9	0.7	-2.0
Patch foraging water rate 12 sec	0.1	0.2	0.5	-0.4	0.1	-0.7
Patch foraging water rate 18 sec	0.6	0.9	1.7	-0.8	1.3	0.5
Patch foraging water rate 24 sec	0.4	0.6	0.9	0.1	0.9	0.9
Patch foraging water rate 6 sec	1.0	1.5	2.4	-1.2	1.6	-0.7
Seeking ratio, delayed vs. immediate footshock	0.4	0.4	1.1	0.0	1.1	-0.3
Distance traveled before self-admin	2.3	2.5	3.5	-0.9	1.9	-1.8
Distance traveled after self-admin	2.2	2.4	5.2	-1.4	2.3	-0.0
Extensor digitorum longus weight	4.5	17.6	23.7	-4.9	4.7	-2.6
Bone: elastic displacement	5.1	5.8	7.5	2.7	-2.4	2.0
Bone: elastic work	2.6	3.3	7.8	1.3	-0.7	2.8
Bone: endosteal estimation	1.0	2.2	2.9	-1.7	0.8	-1.7
Bone: endosteal perimeter	1.9	4.0	6.2	-2.5	1.1	-2.1
Epididymis fat weight	0.8	1.9	2.2	-1.4	1.2	-1.5
Delta time in closed arm before/after self-admin	1.1	1.1	1.6	-1.2	1.3	0.3
Delta time in open arm before/after self-admin	0.4	0.4	0.7	-0.8	-0.7	-0.3
Diff in mean of infusions in LGA sessions	0.2	0.2	0.4	0.5	-0.6	0.3
Delay discount exponential model param	0.2	0.2	0.6	0.0	0.8	0.4
Extinction: sum of active levers before priming	1.2	1.2	1.6	1.3	-1.2	0.7
Active lever presses in extinction session 6	0.2	0.2	0.3	-0.5	-0.4	-0.4
Bone: final force	1.4	2.3	3.4	-1.8	1.8	-0.6
Bone: final moment	1.2	2.0	3.2	-1.8	1.6	-0.3
Food consumed during 24 hour testing period	2.2	2.7	4.1	-2.0	1.1	-1.6
Glucose	1.1	1.6	2.5	-1.6	1.0	-1.2
Heart weight	2.3	3.2	5.6	-2.4	1.4	-1.4
Delay discount hyperbolic model param	0.2	0.2	0.5	-0.1	0.7	0.4
Intermittent access intake day 1-15 change	0.8	0.8	1.6	-1.3	0.5	0.6
Intermittent access intake escalation	0.6	0.6	1.7	-1.3	0.3	0.0
Intermittent access intake escalation 2	0.9	0.9	1.1	-1.1	1.0	0.7
Intermitt. access day 1 inactive lever presses	0.6	0.7	2.0	1.4	0.1	-0.3
Intermitt. access day 15 inactive lever presses	0.2	0.2	0.4	0.5	0.1	-0.6
Intermitt. access escalation Index	0.4	0.3	0.5	-0.5	0.5	-0.7
Intermittent access day 1 total infusions	1.1	1.3	2.2	1.3	-1.5	-0.0
Intermittent access day 15 total infusions	0.1	0.1	0.3	-0.1	-0.5	-0.0
Intermittent access terminal intake (last 3 days)	0.1	0.1	0.2	-0.4	0.1	-0.2
Intermittent access total infusions	0.0	0.1	0.1	0.2	-0.2	-0.3
Intermittent access day 1 locomotion	2.9	3.0	5.4	2.3	-1.8	0.4
Intermittent access day 15 total locomotion	1.3	1.4	3.1	1.0	-1.8	0.5
Intermittent access total locomotion	2.0	2.3	3.8	1.9	-1.2	1.2
Intermittent access standard deviation	0.0	0.0	0.0	-0.2	0.2	0.0
Left kidney weight	1.8	5.2	8.3	-2.9	0.9	-2.5
Right kidney weight	1.6	4.5	8.8	-3.0	0.3	-2.2
Cocaine induced anxiety	0.4	0.4	0.7	0.7	-0.8	0.3
Post-drug Anxiety	0.1	0.2	0.3	0.1	0.5	-0.4
Baseline Anxiety	0.6	0.6	1.6	-0.4	1.3	-0.1
Tail length	1.9	5.8	8.6	-2.9	2.0	-2.2
Length with tail	1.0	3.7	5.5	-2.1	1.2	-2.4
Length without tail	0.2	0.5	0.9	1.0	-0.7	-0.3
Times rat made contact with spout	0.3	0.4	0.7	-0.2	0.8	0.7
Lifetime Intake	0.4	0.4	1.1	-0.2	-0.2	-1.1
Liver weight, left	0.9	1.4	2.1	-1.3	1.4	-0.8
Liver weight, right	0.2	0.3	0.6	-0.8	-0.3	-0.6
Locomotor activity	0.1	0.1	0.2	0.5	-0.1	0.2
Locomotor testing distance	0.2	0.3	0.8	-0.1	-0.3	-0.9
Locomotor testing rearing	0.4	0.6	1.2	-0.4	0.7	-1.1
Locomotion in novel chamber	0.5	0.6	1.0	0.8	1.0	0.3
Locomotion in novel chamber post-restriction	3.2	3.8	6.7	-2.2	2.6	-0.0
Fecal boli incidents, locomotor time 1	1.2	1.3	3.2	0.5	-1.8	0.6
Change in fecal boli incidents, locomotor task	0.8	0.7	1.2	0.3	1.1	-0.9
Time >=10cm from walls, locomotor time 1	0.1	0.1	0.2	0.2	-0.5	-0.3
Bouts of movement, locomotor time 1	1.3	1.4	2.2	1.5	-1.2	0.9
Total resting periods, locomotor time 1	1.9	2.0	2.2	1.5	-1.3	1.5
Rest time, locomotor task time 1	1.9	2.1	5.8	0.6	0.0	2.4
Distance moved, locomotor task time 1	1.0	1.1	3.2	0.0	0.1	-1.8
Vertical activity count, locomotor time 1	1.1	1.1	3.3	-0.3	0.2	-1.8
Time >=10cm from walls, locomotor time 2	0.5	0.5	1.2	1.1	-0.7	-0.1
Bouts of movement, locomotor time 2	2.4	2.6	5.3	-2.3	1.3	-1.0
Total resting periods, locomotor time 2	1.8	1.9	4.1	-2.0	1.0	-0.7
Rest time, locomotor task time 2	0.5	0.6	1.4	0.3	-0.5	1.2
Distance moved, locomotor task time 2	0.4	0.4	1.2	1.1	-0.0	0.4
Vertical activity count, locomotor time 2	0.1	0.1	0.3	0.2	0.0	-0.6
Light reinforcement 1	2.5	4.6	9.4	-2.0	0.4	-3.1
Light reinforcement 2	2.7	3.6	8.7	-1.5	-0.1	-2.9
Bone: marrow area	1.0	2.1	3.0	-1.7	0.9	-1.6
Bone: maximum diameter	3.3	6.1	10.0	-3.2	2.5	-1.4
Bone: maximum force	3.1	5.4	7.6	-2.7	2.8	-1.0
Bone: maximum moment	2.6	4.4	6.5	-2.5	2.5	-0.7
Mean time between licks in bursts	0.2	0.3	0.6	-0.5	-0.8	-0.1
Mean num. licks in bursts	3.1	3.8	5.5	2.1	-2.3	1.1
Cd content in liver	1.6	1.7	2.9	-1.7	1.4	0.5
Co content in liver	0.5	0.6	1.7	0.0	-1.3	-0.1
Cu content in liver	0.5	0.6	1.5	0.5	-0.2	1.2
Fe content in liver	3.2	3.8	5.8	-2.4	-0.0	-2.4
K content in liver	0.4	0.4	0.7	0.7	-0.8	-0.2
Mg content in liver	0.8	0.9	1.2	1.1	-1.1	0.5
Mn content in liver	0.6	0.6	1.4	-0.4	1.2	0.6
Na content in liver	0.5	0.5	0.6	0.8	-0.7	0.5
Rb content in liver	3.1	3.8	7.0	2.0	-2.6	0.8
Se content in liver	1.6	2.0	4.8	-1.1	2.2	0.2
Sr content in liver	0.3	0.3	0.8	-0.2	0.9	0.1
Zn content in liver	0.4	0.4	0.9	0.5	0.4	0.9
Bone: minimum diameter	0.0	0.1	0.1	-0.4	-0.0	0.2
Time in familiar zone, hab. session 1	2.4	2.2	5.8	0.8	0.6	2.4
Time in novel zone, hab. session 1	2.4	2.3	3.8	-0.2	-1.9	-1.8
Total zone transitions, hab. session 1	0.6	0.9	2.3	1.5	-0.4	0.3
Total locomotion distance, hab. session 1	0.8	1.1	1.7	0.7	1.1	1.3
Locomotion velocity, hab. session 1	0.9	1.2	3.1	-0.1	1.8	0.7
Time in familiar zone, hab. session 2	1.0	1.1	3.0	0.4	-0.3	1.7
Time in novel zone, hab. session 2	1.2	1.2	1.7	0.7	-1.3	-1.2
Total zone transitions, hab. session 2	0.4	0.5	1.6	0.1	0.2	-1.3
Total locomotion distance, hab. session 2	0.5	0.7	1.5	-0.7	1.2	-0.4
Locomotion velocity, hab. session 2	0.6	0.8	1.8	-0.8	1.3	-0.3
Novel to familiar place preference ratio	2.9	3.0	5.8	1.8	-2.4	-0.1
Novelty place preference	4.0	4.0	7.0	2.3	-2.6	0.2
Time in novel zone, NPP test	4.7	4.9	8.4	2.5	-2.9	0.3
Total zone transitions, NPP test	0.4	0.6	1.6	0.1	0.5	-1.3
Total locomotion distance, NPP test	1.0	1.3	1.8	-0.8	1.3	-1.3
Locomotion velocity, NPP test	1.2	1.6	2.2	-1.1	1.5	-1.2
Intraocular pressure	1.3	1.9	2.3	-1.5	1.1	-1.4
Delta distance traveled before/after self-admin	0.2	0.3	0.4	-0.6	0.2	0.6
Delta ambulatory time before/after self-admin	0.2	0.2	0.5	-0.2	0.1	0.7
Parametrial fat weight	0.2	0.4	0.7	0.6	0.0	-0.8
Pavlov. Cond. lever latency	5.4	6.9	8.7	2.6	-3.0	2.2
Pavlov. Cond. magazine entry latency	0.7	0.9	1.8	-1.3	0.6	-0.7
Pavlov. Cond. change in total contacts	1.3	1.4	2.0	-1.0	1.1	-1.4
Pavlov. Cond. index score	2.7	3.4	4.6	-2.1	2.0	-1.2
Pavlov. Cond. latency score	2.3	3.0	4.0	-2.0	1.8	-1.2
Pavlov. Cond. lever contacts	3.8	4.5	5.6	-2.2	2.4	-1.7
Pavlov. Cond. magazine entry number	0.8	1.0	1.8	1.3	-0.9	0.6
Pavlov. Cond. intertrial magazine entries	0.1	0.1	0.1	-0.1	0.4	-0.2
Pavlov. Cond. lever-magazine prob. diff.	2.2	2.8	4.0	-2.0	1.9	-0.9
Pavlov. Cond. response bias	2.5	3.1	4.1	-2.0	1.8	-1.4
Pavlov. Cond. lever latency	1.7	2.2	3.6	1.9	-1.8	-0.2
Pavlov. Cond. magazine entry latency	0.1	0.2	0.3	-0.3	-0.4	0.5
Pavlov. Cond. change in total contacts	0.8	1.2	1.8	-0.9	0.9	1.4
Pavlov. Cond. index score	0.4	0.5	0.7	-0.7	0.4	0.8
Pavlov. Cond. latency score	0.5	0.6	0.8	-0.8	0.6	0.9
Pavlov. Cond. lever contacts	1.0	1.4	2.8	-1.7	1.2	0.1
Pavlov. Cond. magazine entry number	0.4	0.5	1.5	0.0	-0.3	-1.2
Pavlov. Cond. intertrial magazine entries	0.3	0.4	0.5	-0.5	0.6	-0.7
Pavlov. Cond. lever-magazine prob. diff.	0.4	0.5	0.8	-0.8	0.5	0.9
Pavlov. Cond. response bias	0.5	0.7	1.2	-1.1	0.8	0.5
Time in closed arm before self-admin	1.8	2.1	3.1	1.5	-1.8	1.0
Time in closed arm after self-admin	0.4	0.4	0.6	0.8	-0.4	0.5
Time in open arm before self-admin	1.0	1.1	2.3	0.0	1.0	-1.5
Time in open arm after self-admin	1.2	1.3	1.8	-1.2	0.7	-1.3
Bone: periosteal estimation	1.8	3.7	5.8	-2.4	1.8	-1.4
Bone: periosteal perimeter	2.0	3.4	5.9	-2.4	1.0	-1.8
Bone: post-yield work	3.1	4.2	7.7	-2.8	1.3	-1.8
Progressive ratio test 1 active lever presses	0.2	0.2	0.5	0.7	-0.1	-0.4
Progressive ratio test 1 breakpoint	0.3	0.3	0.6	0.8	-0.1	-0.5
Progressive ratio test 1 inactive lever presses	0.7	0.8	1.7	0.7	-0.5	-1.3
Progressive ratio test 2 active lever presses	0.6	0.7	1.0	-0.4	-1.0	-0.9
Progressive ratio test 2 breakpoint	0.5	0.5	1.1	-0.2	-1.1	-0.6
Progressive ratio test 2 inactive lever presses	0.1	0.1	0.3	0.2	-0.2	-0.6
Incentive Sensitization - Responses	0.5	0.5	0.6	-0.8	-0.8	-0.5
Incentive Sensitization - Breakpoint	0.5	0.5	0.8	-0.8	-0.9	-0.4
Sum of active levers in priming session hrs 5-6	2.0	1.9	5.5	-0.0	-2.4	-0.4
Progressive ratio	0.2	0.2	0.4	-0.1	-0.6	-0.5
Food seeking constrained by brief footshock	6.1	7.5	9.0	-3.0	2.5	-2.7
Seeking ratio, punishment vs. effort	1.9	2.3	3.4	-1.6	1.8	-1.0
Retroperitoneal fat weight	0.1	0.2	0.2	0.4	-0.4	0.5
Reaction time number correct	0.3	0.4	0.6	-0.8	-0.4	-0.6
Reaction time mean minus median	1.4	1.8	4.1	-0.5	1.1	2.0
Reaction time mean minus median AUC	1.4	1.8	2.1	-1.3	1.4	1.3
Reaction time num false alarms	0.4	0.5	0.8	-0.6	0.6	0.9
Reaction time num false alarms AUC	0.7	1.0	1.9	-1.4	1.0	0.1
Reaction time trials correct on left	0.3	0.4	0.6	-0.8	-0.4	-0.6
Reaction time trials on left	0.3	0.4	0.6	-0.8	-0.5	-0.5
Reaction time mean	1.5	2.1	5.9	0.5	-0.4	2.4
Reaction time mean AUC	1.8	2.4	6.8	0.5	-0.5	2.6
Median of all reaction times	1.5	2.0	4.3	0.8	-1.1	2.1
Reaction time omissions	0.5	0.7	1.2	-0.8	-1.1	0.7
Reaction time false alarm rate	0.2	0.3	0.6	-0.1	0.6	0.8
Reaction time premature initiation rate	3.9	5.2	7.4	2.7	-2.2	1.8
Reaction time premature initiations	2.6	3.7	5.0	2.0	-2.2	1.3
Std. dev. reaction times	1.5	2.1	6.2	0.4	0.2	2.5
Reaction time trials completed	0.3	0.4	0.6	-0.8	-0.5	-0.5
Reaction time trials AUC	0.2	0.3	0.3	-0.6	-0.5	-0.4
Run reversals in cocaine runway, females	1.5	1.4	3.4	1.8	0.3	0.9
Run reversals in cocaine runway, males	0.6	0.6	1.4	1.2	-0.2	0.5
Latency to leave start box in cocaine runway	0.6	0.7	1.7	-0.2	1.3	-0.5
Latency to leave start box in cocaine runway, F	0.2	0.2	0.4	0.3	-0.4	-0.6
Latency to leave start box in cocaine runway, M	1.4	1.4	2.9	-0.3	1.7	-1.0
Std. dev. time between licks in bursts	0.3	0.3	0.7	0.0	-0.9	0.5
Total sessions with >9 infusions	0.7	0.8	2.1	-0.1	-0.6	-1.4
Short access day 1 total inactive lever presses	0.7	0.8	1.5	0.9	0.2	-1.2
Short access day 10 total inactive lever presses	0.2	0.2	0.2	0.4	0.5	-0.5
Short access day 1 total infusions	1.4	1.5	4.1	-0.6	0.3	-2.0
Short access day 10 total infusions	0.5	0.6	1.3	0.2	-0.6	-1.1
Short access total infusions	0.7	0.8	2.1	-0.2	-0.4	-1.5
Short access day 1 locomotion	0.8	0.8	1.3	1.1	-1.1	-0.2
Short access day 10 total locomotion	1.1	1.2	1.7	1.3	-0.9	1.0
Short access total locomotion	1.1	1.2	2.6	1.6	-0.9	0.1
One hour access (0.3 mA shock)	0.4	0.5	0.8	-0.1	-0.9	-0.9
Compulsive drug intake	0.0	0.0	0.0	-0.0	-0.1	-0.2
One hour access (shock baseline)	0.5	0.6	1.0	0.4	-0.9	-1.0
Social response proportion	1.8	1.9	3.6	1.9	-1.1	1.0
Social responses	0.1	0.1	0.2	-0.3	0.4	-0.3
Social time	0.7	0.9	1.8	-1.4	-0.7	-0.7
Soleus weight	1.2	3.5	5.9	-2.0	-0.9	-2.4
Bone: stiffness	3.7	5.8	8.6	-2.7	2.9	-1.2
Tibialis anterior weight	6.0	20.6	28.1	-5.3	4.7	-3.4
Time to tail flick, vehicle, before self-admin	0.9	1.0	2.1	0.8	-1.5	0.4
Time to tail flick, vehicle, after self-admin	0.5	0.6	1.3	-1.1	0.3	-0.6
Time to tail flick, test, before self-admin	0.1	0.1	0.3	0.0	0.5	0.2
Time to tail flick, test, after self-admin	0.3	0.4	0.9	-0.4	0.2	0.9
Delta time to tail flick, vehicle, before/after SA	1.4	1.4	2.9	-1.7	0.9	-0.6
Delta time to tail flick, test, before/after SA	0.4	0.3	0.7	0.1	-0.9	0.5
Tibia length	1.0	2.8	4.2	-2.0	0.3	-2.1
Ambulatory time before self-admin	1.6	1.7	3.2	-0.6	1.2	-1.8
Ambulatory time after self-admin	1.2	1.3	2.0	-1.2	1.4	-0.8
Bone: tissue strength	0.3	0.2	0.4	-0.7	0.5	-0.1
Total heroin consumption	0.6	0.6	1.2	0.6	-1.1	-0.6
Bone: trabecular number	0.7	1.0	2.0	-1.0	1.4	0.1
Bone: trabecular spacing	0.2	0.2	0.3	-0.3	0.6	0.5
Bone: trabecular thickness	0.2	0.2	0.3	0.6	-0.3	0.4
Bone: trabecular tissue density	1.6	2.2	5.4	-0.9	2.3	-0.6
Water consumed over 24 hours	1.6	2.0	2.9	-1.7	1.5	-0.8
Number of responses in last shaping day	2.9	3.0	7.2	-1.3	-0.5	-2.7