chr7:130,737,419-133,838,246

Trait: Tibialis anterior weight

Best TWAS P=1.39e-11 · Best GWAS P=1.34e-10 conditioned to 1.00e+00

Associated models

Tissue Gene RNA modality RNA phenotype h2 # weights Model R2 Model R2 P TWAS Z TWAS P Coloc P Joint
Adipose Scn8a alternative polyA NM_019266.3 0.26 1 0.28 7.6e-31 -6.1 1.07e-09 0.56 FALSE
Adipose Scn8a alternative polyA XM_039078606.1 0.25 1 0.27 1.9e-29 6.1 1.07e-09 0.56 FALSE
Adipose Scn8a alternative polyA NM_019266.3 0.26 1 0.27 4.8e-30 -6.1 1.07e-09 0.56 FALSE
Adipose Scn8a alternative polyA XM_039078606.1 0.26 1 0.27 8.0e-30 6.1 1.07e-09 0.56 FALSE
Adipose Tfcp2 alternative polyA XM_017594896.2 0.03 91 0.01 6.0e-02 -5.84 5.22e-09 0.06 TRUE
Adipose Krt79 alternative TSS XM_003750410.4 0.01 1 0.01 2.5e-02 5.23 1.67e-07 0.03 FALSE
Adipose Acvrl1 gene expression Acvrl1 0.06 1093 0.03 1.7e-04 -6.64 3.06e-11 0.57 FALSE
Adipose Atg101 gene expression Atg101 0.08 1 0.06 9.2e-07 -6.12 9.16e-10 0.31 FALSE
Adipose Dazap2 gene expression Dazap2 0.21 1 0.09 5.4e-10 -5.18 2.25e-07 0.02 FALSE
Adipose Krt79 gene expression Krt79 0.13 1 0.23 1.2e-24 -5.21 1.84e-07 0.02 FALSE
Adipose Krt80 gene expression Krt80 0.09 1097 0.03 7.1e-04 6.11 9.81e-10 0.43 FALSE
Adipose Krt81 gene expression Krt81 0.03 1288 0.02 2.0e-03 6.11 1.00e-09 0.49 FALSE
Adipose Krt86 gene expression Krt86 0.09 1 0.1 2.8e-11 -6.18 6.37e-10 0.45 FALSE
Adipose Scn8a gene expression Scn8a 0.66 1 0.61 1.0e-85 -6.09 1.10e-09 0.56 FALSE
Adipose Slc4a8 gene expression Slc4a8 0.21 25 0.22 1.3e-23 5.42 6.06e-08 0.03 FALSE
Adipose Atg101 isoform ratio NM_001007659.2 0.02 1 0.02 6.4e-03 6.18 6.37e-10 0.03 FALSE
Adipose Atg101 isoform ratio NM_001271114.1 0.05 1 0.03 1.9e-04 -6.25 4.08e-10 0.07 FALSE
Adipose Scn8a isoform ratio NM_019266.3 0.26 1 0.24 1.8e-26 -6.1 1.07e-09 0.56 FALSE
Adipose Scn8a isoform ratio XM_039078607.1 0.03 1 0.01 3.7e-02 -6.14 8.02e-10 0.04 FALSE
Adipose Scn8a isoform ratio XM_039078609.1 0.06 1337 0.05 7.1e-06 -5.72 1.05e-08 0.75 FALSE
Adipose Smagp isoform ratio NM_182817.2 0.02 1571 0.01 1.3e-02 -5.22 1.74e-07 0.06 FALSE
Adipose Atg101 mRNA stability Atg101 0.06 1 0.05 5.7e-06 -6.12 9.16e-10 0.34 FALSE
Adipose Dazap2 mRNA stability Dazap2 0.87 24 0.52 1.1e-67 -5.31 1.11e-07 0.02 FALSE
Adipose Krt80 mRNA stability Krt80 0.15 1097 0.16 3.3e-17 -6.18 6.57e-10 0.58 FALSE
BLA Tamalin alternative polyA NM_138894.1 0.06 1 0.06 4.6e-04 -6.27 3.52e-10 0.05 FALSE
BLA Tamalin alternative polyA XM_039078372.1 0.1 1 0.07 1.2e-04 6.27 3.52e-10 0.07 FALSE
BLA Slc11a2 alternative TSS XM_006242312.4 0.16 1562 0.14 7.0e-08 5.39 7.20e-08 0.71 FALSE
BLA Slc11a2 alternative TSS NM_001399169.1 0.11 1562 0.1 5.2e-06 -5.44 5.25e-08 0.65 FALSE
BLA Slc11a2 alternative TSS XM_006242312.4 0.16 1562 0.13 1.8e-07 5.37 8.03e-08 0.7 FALSE
BLA Tns2 alternative TSS XM_017595336.2 0.03 1033 0.06 2.5e-04 -5.7 1.19e-08 0.44 FALSE
BLA Galnt6 gene expression Galnt6 0.4 1443 0.47 9.8e-28 5.86 4.60e-09 0.76 FALSE
BLA Krt1 gene expression Krt1 0.13 40 0.25 1.4e-13 5.52 3.41e-08 0.38 FALSE
BLA Krt75 gene expression Krt75 0.08 1 0.05 1.2e-03 6.13 8.88e-10 0.04 FALSE
BLA Krt80 gene expression Krt80 0.06 167 0.02 2.6e-02 -5.25 1.49e-07 0.36 FALSE
BLA Pou6f1 gene expression Pou6f1 0.22 1622 0.25 8.0e-14 5.39 6.93e-08 0.02 FALSE
BLA Atg101 isoform ratio NM_001007659.2 0.14 1 0.13 2.4e-07 6.3 2.89e-10 0.58 FALSE
BLA Atg101 isoform ratio NM_001271114.1 0.13 1113 0.09 1.1e-05 6.04 1.55e-09 0.5 FALSE
BLA Rarg isoform ratio XM_008765785.3 0.11 15 0.06 3.1e-04 5.48 4.33e-08 0.33 FALSE
BLA Tamalin isoform ratio NM_138894.1 0.07 1 0.08 6.2e-05 -6.27 3.52e-10 0.08 FALSE
BLA Tamalin isoform ratio XM_039078384.1 0.06 1 0.06 3.9e-04 6.27 3.52e-10 0.05 FALSE
BLA Atg101 intron excision ratio chr7_132398752_132401420 0.07 1 0.05 1.6e-03 6.07 1.31e-09 0.05 FALSE
BLA Atg101 intron excision ratio chr7_132398752_132401715 0.07 1 0.06 3.5e-04 -6.3 2.89e-10 0.12 FALSE
BLA Scn8a mRNA stability Scn8a 0.05 1341 0.02 4.0e-02 5.94 2.83e-09 0.35 FALSE
Brain Pou6f1 alternative polyA NM_001105746.1 0.04 1622 0.03 5.7e-04 -5.79 7.04e-09 0.65 FALSE
Brain Pou6f1 alternative polyA XM_039078244.1 0.04 1622 0.03 5.0e-04 5.78 7.35e-09 0.63 FALSE
Brain Tamalin alternative polyA NM_138894.1 0.08 1 0.06 3.3e-06 -6.36 2.04e-10 0.69 FALSE
Brain Tamalin alternative polyA XM_039078372.1 0.08 1 0.07 9.1e-07 6.36 2.04e-10 0.72 FALSE
Brain Atg101 alternative TSS NM_001007659.2 0.04 3 0.04 1.7e-04 -6.25 4.03e-10 0.44 FALSE
Brain Atg101 alternative TSS XM_006242324.4 0.04 1 0.04 1.6e-04 6.25 4.08e-10 0.43 FALSE
Brain Pou6f1 alternative TSS XM_039078248.1 0.06 1622 0.03 1.6e-03 5.61 2.03e-08 0.7 FALSE
Brain Pou6f1 alternative TSS XM_039078248.1 0.06 1622 0.03 4.4e-04 5.65 1.65e-08 0.69 FALSE
Brain Atg101 gene expression Atg101 0.08 1113 0.07 3.6e-07 6.22 5.04e-10 0.56 FALSE
Brain Dazap2 gene expression Dazap2 0.22 1594 0.06 5.6e-06 5.69 1.24e-08 0.27 FALSE
Brain Galnt6 gene expression Galnt6 0.45 106 0.58 4.6e-66 -5.77 8.03e-09 0.7 FALSE
Brain Krt1 gene expression Krt1 0.12 1 0.14 2.3e-13 -6.07 1.24e-09 0.41 FALSE
Brain Krt77 gene expression Krt77 0.12 1 0.05 1.4e-05 5.23 1.67e-07 0.02 FALSE
Brain LOC108351555 gene expression LOC108351555 0.05 1 0.02 2.9e-03 -6.34 2.28e-10 0.06 FALSE
Brain Atg101 isoform ratio NM_001007659.2 0.08 1 0.07 3.5e-07 6.26 3.77e-10 0.55 FALSE
Brain Atg101 isoform ratio NM_001271114.1 0.07 1113 0.07 1.9e-07 5.98 2.26e-09 0.45 FALSE
Brain Tamalin isoform ratio NM_138894.1 0.08 986 0.07 5.4e-07 6.07 1.27e-09 0.63 FALSE
Brain Atg101 intron excision ratio chr7_132398752_132401420 0.04 1113 0.04 8.5e-05 -6.05 1.41e-09 0.47 FALSE
Brain Atg101 intron excision ratio chr7_132398752_132401715 0.08 95 0.09 1.5e-08 -5.62 1.89e-08 0.41 FALSE
Brain Dazap2 intron excision ratio chr7_131716432_131717118 0.05 1594 0.06 7.5e-06 5.49 4.11e-08 0.41 FALSE
Brain Dazap2 intron excision ratio chr7_131717363_131718880 0.04 1594 0.04 1.6e-04 -5.4 6.65e-08 0.32 FALSE
Brain Atg101 mRNA stability Atg101 0.04 1113 0.03 1.1e-03 6.08 1.21e-09 0.46 FALSE
Brain Igfbp6 mRNA stability Igfbp6 0.03 1028 0.02 9.7e-03 5.86 4.77e-09 0.4 TRUE
Brain Pou6f1 mRNA stability Pou6f1 0.36 1622 0.12 2.7e-11 -5.82 5.99e-09 0.19 FALSE
Brain Scn8a mRNA stability Scn8a 0.02 1341 0.02 6.5e-03 5.96 2.60e-09 0.44 FALSE
Brain Slc4a8 mRNA stability Slc4a8 0.24 1392 0.27 1.6e-25 -5.32 1.07e-07 0.59 FALSE
Brain Tfcp2 mRNA stability Tfcp2 0.1 1646 0.11 5.3e-10 -5.6 2.14e-08 0.43 FALSE
Eye Bin2 gene expression Bin2 0.4 1 0.06 4.5e-02 5.26 1.45e-07 0.06 FALSE
Eye Krt6a gene expression Krt6a 0.55 1 0.16 1.7e-03 -6.15 7.65e-10 0.06 FALSE
Eye Krt7 gene expression Krt7 0.83 1124 0.05 6.0e-02 5.52 3.41e-08 0.2 FALSE
Eye LOC120093742 gene expression LOC120093742 0.37 1331 0.13 5.7e-03 6.09 1.14e-09 0.22 FALSE
Eye LOC683313 gene expression LOC683313 0.81 1 0.22 2.3e-04 6.15 7.65e-10 0.06 FALSE
Eye Atg101 isoform ratio NM_001007659.2 0.37 80 0.06 4.0e-02 6.33 2.43e-10 0.21 FALSE
Eye Atg101 isoform ratio NM_001271114.1 0.68 1 0.1 1.2e-02 -6.32 2.69e-10 0.06 FALSE
Eye Krt5 intron excision ratio chr7_132832634_132851232 0.45 1356 0.15 2.5e-03 6.12 9.20e-10 0.33 FALSE
Eye Krt5 intron excision ratio chr7_132850706_132851232 0.43 1356 0.15 2.7e-03 -6.07 1.30e-09 0.32 FALSE
Eye Krt6a intron excision ratio chr7_132832634_132851232 0.45 1341 0.15 2.5e-03 6.12 9.24e-10 0.33 FALSE
Eye Krt6a intron excision ratio chr7_132850706_132851232 0.43 1341 0.15 2.7e-03 -6.07 1.31e-09 0.32 FALSE
Eye Dazap2 mRNA stability Dazap2 0.6 1594 0.28 3.2e-05 -5.36 8.10e-08 0.34 FALSE
IL Pou6f1 alternative TSS XM_039078246.1 0.18 1622 0.07 7.3e-03 -5.7 1.17e-08 0.21 FALSE
IL Krt1 gene expression Krt1 0.13 1 0.09 3.1e-03 -6.16 7.35e-10 0.06 FALSE
IL Pou6f1 gene expression Pou6f1 0.45 1622 0.27 2.6e-07 5.95 2.66e-09 0.66 FALSE
LHb Dazap2 gene expression Dazap2 0.29 3 0.16 1.4e-04 5.36 8.52e-08 0.56 FALSE
LHb Galnt6 gene expression Galnt6 0.72 409 0.41 6.1e-11 -5.76 8.61e-09 0.62 FALSE
LHb Krt77 gene expression Krt77 0.17 1268 0.17 8.8e-05 -5.82 5.86e-09 0.3 FALSE
Liver Tns2 alternative TSS XM_017595338.2 0.07 55 0.06 2.7e-07 5.37 8.04e-08 0 FALSE
Liver Atg101 gene expression Atg101 0.02 1113 0.01 1.1e-02 6.03 1.66e-09 0.34 FALSE
Liver Csad gene expression Csad 0.07 1121 0.03 1.0e-04 -5.42 5.97e-08 0.04 FALSE
Liver Krt7 gene expression Krt7 0.03 1 0.01 2.7e-02 6.1 1.05e-09 0.03 FALSE
Liver Krt71 gene expression Krt71 0.21 65 0.11 1.1e-12 6.43 1.32e-10 0.57 FALSE
Liver Pou6f1 gene expression Pou6f1 0.6 64 0.25 5.9e-28 -6.28 3.29e-10 0 FALSE
Liver Tmdd1 gene expression Tmdd1 0.05 3 0.04 2.8e-05 5.89 3.84e-09 0.62 FALSE
Liver Atg101 isoform ratio NM_001007659.2 0.04 7 0.05 4.7e-06 -6.1 1.09e-09 0.52 FALSE
Liver Atg101 isoform ratio NM_001271114.1 0.07 1113 0.06 2.0e-07 5.95 2.61e-09 0.46 FALSE
Liver Dazap2 isoform ratio NM_001395672.1 0.05 20 0.02 6.4e-03 -5.45 5.00e-08 0.06 FALSE
Liver Smagp isoform ratio NM_182817.2 0.03 1571 0.03 5.9e-04 -5.68 1.38e-08 0.31 FALSE
Liver Atg101 intron excision ratio chr7_132398752_132401420 0.04 1 0.02 9.8e-04 5.48 4.18e-08 0.03 FALSE
Liver Atg101 intron excision ratio chr7_132398752_132401715 0.03 1113 0.03 3.4e-04 6.02 1.77e-09 0.44 FALSE
Liver Atg101 mRNA stability Atg101 0.03 1 0.03 2.9e-04 -6.08 1.17e-09 0.04 FALSE
Liver Pou6f1 mRNA stability Pou6f1 0.03 1618 0.01 1.6e-02 -5.59 2.26e-08 0.3 FALSE
NAcc Scn8a alternative polyA XM_039078606.1 0.03 1341 0.03 1.6e-04 -5.84 5.24e-09 0.53 FALSE
NAcc Scn8a alternative polyA XM_039078606.1 0.03 1341 0.03 2.2e-04 -5.86 4.58e-09 0.54 FALSE
NAcc Tamalin alternative polyA NM_138894.1 0.06 1 0.06 2.8e-07 -6.27 3.52e-10 0.59 FALSE
NAcc Tamalin alternative polyA XM_039078372.1 0.06 1 0.06 1.3e-07 6.27 3.52e-10 0.6 FALSE
NAcc Pou6f1 alternative TSS XM_039078248.1 0.06 1622 0.03 4.3e-04 5.7 1.22e-08 0.64 FALSE
NAcc Scn8a alternative TSS XM_039078609.1 0.02 1341 0.01 1.2e-02 -6.1 1.08e-09 0.5 FALSE
NAcc Tns2 alternative TSS NM_001108114.2 0.01 1033 0.02 9.4e-04 5.59 2.33e-08 0.19 FALSE
NAcc Tns2 alternative TSS NM_001108114.2 0.02 1033 0.02 1.8e-03 5.66 1.48e-08 0.21 FALSE
NAcc Atg101 gene expression Atg101 0.03 1 0.05 3.4e-06 -6.27 3.52e-10 0.15 FALSE
NAcc Galnt6 gene expression Galnt6 0.26 31 0.41 1.4e-51 5.49 4.10e-08 0.25 FALSE
NAcc Krt1 gene expression Krt1 0.1 1 0.29 9.6e-34 -5.37 7.94e-08 0.01 FALSE
NAcc Krt71 gene expression Krt71 0.09 1 0.19 5.0e-22 -6.07 1.24e-09 0.35 FALSE
NAcc Krt75 gene expression Krt75 0.03 1 0.03 2.7e-04 -6.1 1.08e-09 0.12 FALSE
NAcc Letmd1 gene expression Letmd1 0.05 1593 0.04 1.0e-05 5.41 6.23e-08 0.49 FALSE
NAcc Pou6f1 gene expression Pou6f1 0.31 1622 0.26 3.1e-30 5.19 2.10e-07 0.01 TRUE
NAcc Slc4a8 gene expression Slc4a8 0.04 1392 0.04 8.5e-06 -5.77 7.78e-09 0.62 FALSE
NAcc Atg101 isoform ratio NM_001007659.2 0.04 21 0.04 1.1e-05 -6.38 1.77e-10 0.61 FALSE
NAcc Atg101 isoform ratio NM_001271114.1 0.32 20 0.06 7.3e-08 6.21 5.20e-10 0.52 FALSE
NAcc Tamalin isoform ratio NM_138894.1 0.11 1 0.11 1.4e-12 -6.38 1.77e-10 0.76 FALSE
NAcc Tamalin isoform ratio XM_039078384.1 0.07 15 0.07 1.3e-08 6.19 5.95e-10 0.61 FALSE
NAcc Atg101 intron excision ratio chr7_132398752_132401420 0.02 1113 0.02 3.5e-03 -6.19 6.15e-10 0.42 FALSE
NAcc Atg101 intron excision ratio chr7_132398752_132401715 0.03 1113 0.02 1.3e-03 6.19 6.09e-10 0.49 FALSE
NAcc Dazap2 intron excision ratio chr7_131716432_131717118 0.03 15 0.02 3.2e-03 6.34 2.31e-10 0.6 FALSE
NAcc Galnt6 intron excision ratio chr7_131819659_131826992 0.03 21 0.02 5.3e-03 -5.21 1.91e-07 0.39 FALSE
NAcc Scn8a intron excision ratio chr7_132125810_132126074 0.02 1341 0.01 2.2e-02 -6.01 1.85e-09 0.43 FALSE
NAcc Atg101 mRNA stability Atg101 0.03 1 0.04 3.7e-05 6.27 3.52e-10 0.53 TRUE
NAcc Krt71 mRNA stability Krt71 0.03 1 0.03 4.0e-04 -6.07 1.31e-09 0.09 FALSE
NAcc Rarg mRNA stability Rarg 0.02 931 0.01 1.5e-02 5.46 4.79e-08 0.34 FALSE
OFC Pou6f1 gene expression Pou6f1 0.45 81 0.22 6.3e-06 -5.43 5.68e-08 0.12 FALSE
OFC Atg101 isoform ratio NM_001271114.1 0.18 1 0.08 5.8e-03 -6.04 1.51e-09 0.05 FALSE
OFC Dazap2 isoform ratio NM_001395672.1 0.25 1 0.09 3.3e-03 -6.07 1.29e-09 0.07 FALSE
OFC Atg101 intron excision ratio chr7_132398752_132401715 0.21 1 0.11 1.4e-03 -6.14 8.02e-10 0.05 FALSE
PL Tamalin alternative polyA NM_138894.1 0.13 1 0.12 7.0e-13 -6.38 1.77e-10 0.76 FALSE
PL Tamalin alternative polyA XM_039078372.1 0.16 1 0.13 9.9e-14 6.42 1.34e-10 0.8 FALSE
PL Pou6f1 alternative TSS XM_039078248.1 0.03 1622 0.03 4.8e-04 5.62 1.95e-08 0.39 FALSE
PL Pou6f1 alternative TSS XM_039078248.1 0.04 1622 0.03 6.1e-04 5.53 3.18e-08 0.44 FALSE
PL Galnt6 gene expression Galnt6 0.16 24 0.2 1.1e-21 5.22 1.75e-07 0.05 FALSE
PL Krt1 gene expression Krt1 0.11 1 0.14 1.3e-15 -5.36 8.19e-08 0.01 FALSE
PL Krt76 gene expression Krt76 0.02 1225 0.01 1.4e-02 5.78 7.51e-09 0.21 FALSE
PL Krt80 gene expression Krt80 0.06 1097 0.08 8.5e-09 6.17 6.97e-10 0.55 FALSE
PL Pou6f1 gene expression Pou6f1 0.28 1622 0.33 1.4e-37 5.35 8.85e-08 0 FALSE
PL Tamalin gene expression Tamalin 0.05 35 0.03 3.3e-04 -6.76 1.39e-11 0.59 TRUE
PL Atg101 isoform ratio NM_001007659.2 0.08 1113 0.09 4.4e-10 -6.02 1.79e-09 0.49 FALSE
PL Atg101 isoform ratio NM_001271114.1 0.08 1113 0.1 1.4e-10 6.06 1.34e-09 0.53 FALSE
PL Dazap2 isoform ratio XM_039078934.1 0.05 1594 0.02 4.1e-03 -5.27 1.36e-07 0.59 FALSE
PL Tamalin isoform ratio NM_138894.1 0.26 41 0.13 2.2e-14 -6.38 1.71e-10 0.71 FALSE
PL Tamalin isoform ratio XM_039078384.1 0.21 1 0.14 7.7e-15 6.42 1.34e-10 0.8 FALSE
PL Atg101 intron excision ratio chr7_132398752_132401420 0.06 1113 0.04 9.2e-06 -6.22 4.85e-10 0.56 FALSE
PL Atg101 intron excision ratio chr7_132398752_132401715 0.06 1113 0.06 5.2e-07 6.04 1.52e-09 0.53 FALSE
PL Galnt6 mRNA stability Galnt6 0.02 1443 0.02 2.7e-03 5.49 3.91e-08 0.24 FALSE
PL Slc4a8 mRNA stability Slc4a8 0.05 1392 0.04 5.0e-05 -5.72 1.04e-08 0.74 FALSE
pVTA Galnt6 gene expression Galnt6 0.43 1443 0.48 1.9e-23 5.65 1.58e-08 0.54 FALSE
pVTA Krt1 gene expression Krt1 0.17 19 0.2 3.7e-09 6.04 1.56e-09 0.42 FALSE
pVTA Krt75 gene expression Krt75 0.06 1285 0.06 1.1e-03 -6.02 1.77e-09 0.42 FALSE
pVTA Krt77 gene expression Krt77 0.08 1268 0.09 1.6e-04 -5.89 3.93e-09 0.26 FALSE
pVTA Slc4a8 gene expression Slc4a8 0.08 1 0.1 6.8e-05 5.26 1.45e-07 0.04 FALSE
pVTA Atg101 isoform ratio NM_001271114.1 0.06 1 0.05 4.8e-03 -6.34 2.27e-10 0.05 FALSE
pVTA Tamalin isoform ratio NM_138894.1 0.08 986 0.04 8.6e-03 5.84 5.13e-09 0.34 FALSE
pVTA Atg101 intron excision ratio chr7_132398752_132401420 0.07 16 0.05 4.6e-03 6.13 8.64e-10 0.45 TRUE
pVTA Atg101 intron excision ratio chr7_132398752_132401715 0.07 1113 0.07 7.8e-04 6.13 8.82e-10 0.47 FALSE
RMTg Galnt6 gene expression Galnt6 0.15 1443 0.06 1.3e-02 5.61 2.08e-08 0.24 FALSE
RMTg Tmprss12 gene expression Tmprss12 0.26 14 0.07 6.8e-03 5.26 1.44e-07 0.42 FALSE
RMTg LOC103692984 intron excision ratio chr7_132330480_132337695 0.74 1 0.12 3.2e-04 -6.34 2.27e-10 0.06 FALSE
RMTg LOC103692984 intron excision ratio chr7_132335799_132337695 0.72 1 0.15 8.8e-05 6.34 2.27e-10 0.07 FALSE