Best TWAS P=2.762199e-08 · Best GWAS P=4.439196e-07 conditioned to 0.5648531
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Adipose | Pigh | gene expression | ENSRNOG00000010914 | 0.11 | 0.02 | enet | 17 | 0.07 | 3.4e-08 | 3.6 | 5.3 | 1.0e-07 | 0.77 | 0.37 | 0.63 | FALSE |
| 2 | Adipose | Rdh11 | gene expression | ENSRNOG00000054770 | 0.22 | 0.14 | enet | 67 | 0.17 | 3.6e-18 | -4.3 | 5.1 | 3.0e-07 | 0.85 | 0.50 | 0.49 | FALSE |
| 3 | BLA | Pigh | alternative polyA | ENSRNOT00000014775 | 0.12 | 0.04 | enet | 30 | 0.06 | 5.1e-04 | -4.8 | -5.2 | 2.2e-07 | -0.69 | 0.35 | 0.55 | FALSE |
| 4 | BLA | Pigh | alternative polyA | ENSRNOT00000101349 | 0.16 | 0.05 | blup | 2175 | 0.07 | 8.8e-05 | -4.8 | 5.3 | 1.3e-07 | 0.72 | 0.37 | 0.60 | FALSE |
| 5 | BLA | Pigh | gene expression | ENSRNOG00000010914 | 0.25 | 0.14 | enet | 114 | 0.20 | 5.3e-11 | -4.8 | 5.5 | 3.8e-08 | 0.84 | 0.25 | 0.75 | FALSE |
| 6 | BLA | Pigh | isoform ratio | ENSRNOT00000014775 | 0.19 | 0.09 | enet | 119 | 0.13 | 2.8e-07 | -4.8 | -5.2 | 2.2e-07 | -0.74 | 0.43 | 0.56 | FALSE |
| 7 | BLA | Pigh | isoform ratio | ENSRNOT00000101349 | 0.18 | 0.10 | enet | 156 | 0.11 | 1.0e-06 | -4.8 | 5.4 | 8.0e-08 | 0.75 | 0.30 | 0.69 | FALSE |
| 8 | Brain | Atp6v1d | mRNA stability | ENSRNOG00000009080 | 0.09 | 0.01 | blup | 1744 | 0.04 | 3.0e-04 | -4.9 | -5.1 | 3.1e-07 | -0.74 | 0.15 | 0.79 | FALSE |
| 9 | Liver | Pigh | isoform ratio | ENSRNOT00000101349 | 0.03 | 0.00 | blup | 2174 | 0.00 | 9.9e-02 | -4.5 | 5.3 | 1.1e-07 | 0.73 | 0.24 | 0.45 | FALSE |
| 10 | NAcc | Mpp5 | mRNA stability | ENSRNOG00000008788 | 0.36 | 0.12 | enet | 9 | 0.12 | 1.1e-03 | -4.8 | 5.3 | 1.4e-07 | 0.73 | 0.14 | 0.61 | FALSE |
| 11 | PL | Mpp5 | mRNA stability | ENSRNOG00000008788 | 0.77 | 0.33 | blup | 1508 | 0.41 | 7.4e-11 | -4.7 | 5.2 | 2.4e-07 | 0.66 | 0.14 | 0.86 | FALSE |
| 12 | PL2 | Pigh | gene expression | ENSRNOG00000010914 | 0.45 | 0.17 | blup | 2175 | 0.24 | 2.6e-13 | -4.4 | 5.6 | 2.8e-08 | 0.86 | 0.30 | 0.70 | TRUE |
| 13 | PL2 | Mpp5 | mRNA stability | ENSRNOG00000008788 | 0.67 | 0.38 | enet | 105 | 0.41 | 1.3e-23 | -4.5 | 5.2 | 1.6e-07 | 0.81 | 0.26 | 0.73 | FALSE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.