Hub : Genes

Dock5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability Dock5 0.14 0.13 1.0e-13 0.11 0.11 0.12 0.11 1.6e-12 1.2e-12 8.4e-13 1.5e-12
2 NAcc mRNA stability Dock5 0.02 0.02 1.4e-03 0.01 0.01 0 0 3.7e-02 2.1e-02 4.5e-02 6.3e-02
3 LHb mRNA stability Dock5 0.2 0.17 2.9e-03 0.04 0.05 0.04 0.04 4.2e-02 2.1e-02 4.0e-02 4.5e-02
4 PL gene expression Dock5 0.04 0.04 1.7e-04 0.02 0.03 0.03 0.03 2.8e-03 1.4e-04 7.5e-04 6.2e-04
5 Brain alternative polyA XM_039093339.2 0.06 0.05 3.7e-05 0.04 0.05 0.04 0.04 6.5e-05 4.1e-05 1.8e-04 1.3e-04
6 Brain alternative polyA NM_001372012.1 0.05 0.05 4.3e-05 0.04 0.04 0.03 0.04 2.1e-04 4.5e-05 4.0e-04 1.8e-04
7 LHb gene expression Dock5 0.44 0.25 2.7e-07 0.11 0.22 0.17 0.17 1.3e-03 7.6e-06 7.8e-05 8.1e-05
8 Brain mRNA stability Dock5 0.06 0.05 2.3e-05 0.05 0.05 0.04 0.05 1.3e-05 9.2e-06 6.7e-05 1.3e-05
9 Brain isoform ratio XM_039093339.2 0.07 0.06 5.5e-06 0.05 0.06 0.05 0.05 9.6e-06 4.4e-06 1.4e-05 1.4e-05
10 Brain gene expression Dock5 0.24 0.14 0.0e+00 0.25 0.26 0.26 0.25 1.9e-23 3.4e-24 8.6e-24 1.7e-23
11 NAcc gene expression Dock5 0.1 0.08 3.1e-12 0.07 0.08 0.07 0.07 1.6e-11 1.2e-11 1.8e-11 2.9e-11
12 PL isoform ratio NM_001372012.1 0.04 0.05 4.1e-03 0.02 0.02 0.02 0.02 1.0e-03 2.2e-03 1.7e-03 1.1e-03
13 PL isoform ratio XM_039093339.2 0.45 0.33 1.2e-03 0.03 0.02 0.01 0.02 9.3e-04 2.4e-03 1.0e-02 2.6e-03
14 Adipose gene expression Dock5 0.11 0.1 1.1e-10 0.09 0.09 0.09 0.09 4.0e-10 4.3e-10 5.3e-10 5.3e-10
15 Liver gene expression Dock5 0.11 0.1 5.1e-11 0.09 0.09 0.08 0.08 2.9e-10 4.4e-10 2.5e-09 1.8e-09
16 pVTA gene expression Dock5 0.39 0.28 0.0e+00 0.27 0.29 0.29 0.29 1.1e-21 1.0e-23 3.4e-23 1.8e-23
17 NAcc isoform ratio XM_039093339.2 0.03 0.04 2.8e-04 0.01 0.02 0.02 0.01 1.9e-03 4.9e-04 4.7e-04 2.1e-03
18 Liver mRNA stability Dock5 0.03 0.03 1.7e-03 0.02 0.02 0.02 0.02 1.4e-03 1.5e-03 1.2e-03 1.6e-03
19 IC gene expression Dock5 0.14 0.13 7.0e-05 0.1 0.1 0.1 0.11 8.1e-05 8.5e-05 7.7e-05 2.8e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density1.52.53.01.71.61.61.61.6-1.61.61.61.71.61.6-1.71.71.71.71.60.91.70.0
Area under the delay curve0.10.10.2-0.4-0.4-0.4-0.4-0.40.4-0.4-0.4-0.4-0.4-0.40.3-0.3-0.3-0.3-0.4-0.5-0.30.0
BMI with tail0.31.14.1-1.0-1.1-1.1-1.1-1.11.1-1.1-1.1-1.0-1.0-1.00.9-0.9-0.6-0.6-1.0-2.0-0.80.0
BMI without tail0.00.00.20.10.00.00.00.0-0.00.00.00.00.00.0-0.10.10.20.20.1-0.40.10.0
Body weight0.62.65.9-1.7-1.7-1.7-1.7-1.71.7-1.7-1.7-1.7-1.6-1.71.5-1.5-1.1-1.1-1.6-2.4-1.50.0
Weight adjusted by age1.42.12.4-1.5-1.5-1.5-1.5-1.51.5-1.5-1.5-1.5-1.5-1.51.4-1.4-1.5-1.5-1.5-1.4-1.50.0
Bone surface0.71.31.51.21.21.21.21.2-1.21.21.21.21.21.2-1.21.21.21.21.20.61.20.0
Bone volume0.81.41.71.31.21.21.21.2-1.21.21.21.31.31.2-1.21.21.31.31.20.61.30.0
Breakpoint value in progressive ratio session0.10.11.1-0.3-0.3-0.3-0.3-0.30.3-0.3-0.3-0.3-0.3-0.30.3-0.3-0.1-0.1-0.3-1.1-0.30.0
Number of licking bursts0.00.00.0-0.1-0.1-0.1-0.1-0.10.1-0.1-0.1-0.0-0.0-0.00.0-0.0-0.2-0.2-0.0-0.2-0.00.0
Context. condit. distance diff. score0.91.01.31.11.01.01.01.0-1.01.01.01.01.11.0-1.11.11.11.11.10.51.10.0
Locomotion velocity, session 10.30.31.7-0.5-0.6-0.5-0.5-0.50.5-0.5-0.5-0.5-0.5-0.50.4-0.4-0.2-0.2-0.5-1.3-0.30.0
Locomotion distance, session 10.00.00.4-0.1-0.1-0.1-0.1-0.10.1-0.1-0.1-0.1-0.1-0.10.1-0.10.20.2-0.1-0.60.00.0
Locomotion velocity, session 20.00.00.2-0.00.10.00.00.0-0.00.00.0-0.0-0.0-0.00.2-0.2-0.1-0.1-0.00.4-0.10.0
Locomotion distance, session 20.00.00.00.00.0-0.0-0.0-0.00.0-0.0-0.0-0.0-0.0-0.00.0-0.00.20.2-0.0-0.20.00.0
Locomotion velocity, session 30.70.80.9-0.9-0.9-0.9-0.9-0.90.9-0.9-0.9-0.9-0.9-0.90.9-0.9-0.9-0.9-0.9-0.6-0.90.0
Locomotion distance, session 30.20.22.1-0.2-0.0-0.1-0.1-0.10.1-0.1-0.1-0.2-0.2-0.20.4-0.4-0.6-0.6-0.21.5-0.50.0
Stereotopy head waving bouts, day 30.60.71.1-0.8-0.9-0.9-0.9-0.90.9-0.9-0.9-0.9-0.9-0.90.8-0.8-0.7-0.7-0.9-1.0-0.80.0
Stereotopy head waving duration, day 32.02.44.7-1.6-1.7-1.7-1.7-1.61.6-1.7-1.7-1.6-1.6-1.61.4-1.4-1.3-1.3-1.6-2.2-1.40.0
Locomotion velocity, session 73.94.24.92.22.12.12.12.1-2.12.12.12.12.12.1-2.12.12.22.22.12.02.10.0
Locomotion distance, session 73.74.75.82.42.22.22.22.2-2.22.22.22.22.22.2-2.42.42.42.42.21.32.30.0
Stereotopy head waving bouts, day 71.41.62.3-1.4-1.2-1.2-1.2-1.21.2-1.2-1.2-1.3-1.3-1.31.5-1.5-1.5-1.5-1.30.0-1.50.0
Stereotopy head waving duration, day 72.12.53.4-1.8-1.5-1.6-1.6-1.61.6-1.6-1.6-1.6-1.6-1.61.8-1.8-1.8-1.8-1.6-0.4-1.80.0
Locomotion velocity, session 80.00.00.0-0.1-0.1-0.1-0.1-0.10.1-0.1-0.1-0.1-0.1-0.10.1-0.1-0.0-0.0-0.10.0-0.10.0
Locomotion distance, session 80.50.81.30.90.90.90.90.9-0.90.90.90.90.90.9-0.90.91.11.10.90.11.00.0
Degree of sensitization distance6.76.910.12.92.52.52.52.6-2.62.52.52.72.72.6-3.13.13.23.22.70.23.10.0
Degree of sensitization stereotypy1.11.21.8-1.2-1.0-1.0-1.0-1.11.1-1.0-1.0-1.1-1.1-1.11.3-1.3-1.3-1.3-1.10.1-1.30.0
Conditioned locomotion0.00.00.4-0.10.10.10.10.1-0.10.10.10.10.10.10.2-0.2-0.1-0.10.10.6-0.20.0
Cocaine response after cond. corrected0.40.40.6-0.7-0.6-0.7-0.7-0.70.7-0.7-0.7-0.7-0.7-0.70.7-0.7-0.7-0.7-0.70.0-0.80.0
Cocaine response after cond. not corrected0.20.30.4-0.6-0.5-0.5-0.5-0.50.5-0.5-0.5-0.6-0.6-0.60.6-0.6-0.6-0.6-0.60.1-0.60.0
Cocaine response before conditioning0.20.30.30.60.50.50.50.6-0.60.50.60.60.60.6-0.60.60.50.50.60.10.60.0
Saline control response0.20.30.40.60.50.60.60.6-0.60.60.60.60.60.6-0.60.60.60.60.60.00.60.0
Bone: connectivity density2.74.24.82.22.12.12.12.1-2.12.12.12.12.12.1-2.12.12.12.12.11.82.10.0
Bone: cortical apparent density0.10.10.40.30.30.30.30.3-0.30.30.30.30.30.3-0.30.30.60.60.3-0.60.40.0
Bone: cortical area0.00.00.00.10.10.10.10.1-0.10.10.10.10.10.1-0.10.10.10.10.1-0.00.10.0
Bone: cortical porosity1.31.41.7-1.3-1.2-1.2-1.2-1.21.2-1.2-1.2-1.2-1.2-1.21.3-1.3-1.3-1.3-1.2-0.9-1.30.0
Bone: cortical porosity0.80.91.0-1.0-0.9-0.9-0.9-1.01.0-0.9-0.9-1.0-1.0-1.01.0-1.0-1.0-1.0-0.9-0.7-1.00.0
Bone: cortical thickness0.00.00.0-0.00.00.00.00.0-0.00.00.00.00.00.00.0-0.00.10.10.0-0.0-0.00.0
Bone: cortical thickness0.00.00.10.10.10.10.10.1-0.10.10.10.10.10.1-0.00.00.00.00.10.30.00.0
Bone: cortical tissue density0.10.20.50.40.30.30.30.3-0.30.30.30.30.30.3-0.30.30.70.70.3-0.60.40.0
Condit. Reinf. active minus inactive responses0.60.71.9-0.9-0.9-0.9-0.9-0.90.9-0.9-0.9-0.9-0.9-0.90.8-0.8-0.6-0.6-0.9-1.4-0.70.0
Condit. Reinf. active-inactive response ratio2.52.73.6-1.7-1.7-1.7-1.7-1.71.7-1.7-1.7-1.7-1.7-1.71.6-1.6-1.4-1.4-1.7-1.9-1.60.0
Condit. Reinf. active responses0.00.10.7-0.1-0.2-0.2-0.2-0.20.2-0.2-0.2-0.1-0.1-0.10.0-0.00.20.2-0.1-0.90.00.0
Condit. Reinf. inactive responses2.42.93.41.81.71.71.71.8-1.81.71.71.81.81.8-1.81.81.81.81.81.31.80.0
Incentive salience index mean1.01.22.5-1.2-1.2-1.2-1.2-1.21.2-1.2-1.2-1.2-1.2-1.21.1-1.1-0.8-0.8-1.1-1.6-1.00.0
Condit. Reinf. lever presses0.50.71.6-0.9-0.9-0.9-0.9-0.90.9-0.9-0.9-0.9-0.9-0.90.9-0.9-0.6-0.6-0.9-1.3-0.80.0
Condit. Reinf. active minus inactive responses0.40.50.60.70.70.70.70.7-0.70.70.70.70.70.7-0.70.70.60.60.70.60.70.0
Condit. Reinf. active-inactive response ratio0.00.00.1-0.1-0.1-0.1-0.1-0.10.1-0.1-0.1-0.1-0.1-0.10.1-0.1-0.1-0.1-0.1-0.3-0.10.0
Condit. Reinf. active responses0.91.21.51.21.11.21.21.2-1.21.21.21.21.21.2-1.21.20.90.91.21.11.10.0
Condit. Reinf. inactive responses1.72.22.61.61.61.61.61.6-1.61.61.61.61.61.6-1.61.61.31.31.61.51.50.0
Condit. Reinf. lever presses0.10.20.30.40.40.40.40.4-0.40.40.40.50.50.5-0.40.40.20.20.40.50.40.0
Condit. Reinf. lever reinforcers received0.71.01.31.11.01.01.01.0-1.01.01.01.11.11.1-1.11.10.80.81.10.91.10.0
Conditioned reinforcement - actives1.01.72.91.41.31.31.31.3-1.31.31.31.31.31.3-1.31.31.71.71.30.41.40.0
Conditioned reinforcement - inactives3.14.55.52.32.22.22.22.2-2.22.22.22.22.22.2-2.32.32.02.02.21.92.30.0
Conditioned locomotion0.10.20.40.40.40.40.40.4-0.40.40.40.40.40.4-0.40.40.60.60.40.00.50.0
Patch foraging indifference point 0 sec1.83.44.22.01.91.91.91.9-1.91.91.91.91.91.9-1.91.92.02.01.91.22.00.0
Patch foraging indifference point AUC0.30.50.9-0.7-0.7-0.7-0.7-0.70.7-0.7-0.7-0.7-0.7-0.70.7-0.7-0.9-0.9-0.7-0.1-0.80.0
Delay disc. indifference point, 0s delay0.20.20.40.50.40.40.40.4-0.40.40.40.40.50.4-0.60.60.50.50.4-0.20.60.0
Delay disc. indifference point, 16s delay0.30.30.40.50.60.60.60.6-0.60.60.60.60.60.6-0.60.60.60.60.60.40.60.0
Delay disc. indifference point, 2s delay1.41.51.9-1.3-1.3-1.3-1.3-1.31.3-1.3-1.3-1.3-1.3-1.31.2-1.2-1.4-1.4-1.2-1.2-1.20.0
Delay disc. indifference point, 24s delay0.20.20.8-0.5-0.5-0.5-0.5-0.50.5-0.5-0.5-0.5-0.5-0.50.4-0.4-0.3-0.3-0.5-0.9-0.30.0
Delay disc. indifference point, 4s delay1.81.92.4-1.4-1.4-1.4-1.4-1.41.4-1.4-1.4-1.4-1.4-1.41.4-1.4-1.6-1.6-1.4-0.9-1.40.0
Delay disc. indifference point, 8s delay0.00.00.2-0.0-0.1-0.1-0.1-0.00.1-0.1-0.1-0.0-0.0-0.0-0.00.00.10.1-0.0-0.40.00.0
Indifference point function ln k0.00.10.30.20.10.20.10.2-0.20.20.20.20.20.2-0.30.30.50.50.2-0.50.30.0
Indifference point function log k0.00.10.30.20.10.20.10.2-0.20.20.20.20.20.2-0.30.30.50.50.2-0.50.30.0
Patch foraging total patch changes 0 sec1.42.63.41.81.61.61.61.6-1.61.61.61.61.61.6-1.71.71.81.81.60.91.80.0
Patch foraging total patch changes 12 sec0.50.70.90.90.90.90.90.9-0.90.90.90.90.90.9-0.90.90.70.70.90.80.90.0
Patch foraging total patch changes 18 sec1.01.51.91.41.31.31.31.3-1.31.31.31.31.31.3-1.31.31.11.11.31.31.20.0
Patch foraging total patch changes 24 sec0.00.00.3-0.1-0.1-0.1-0.1-0.10.1-0.1-0.1-0.1-0.1-0.10.1-0.1-0.1-0.1-0.1-0.6-0.00.0
Patch foraging total patch changes 6 sec0.30.40.60.80.60.60.60.6-0.60.60.60.70.70.7-0.80.80.70.70.70.20.80.0
Patch foraging time to switch 0 sec0.51.01.21.01.11.11.11.1-1.11.11.11.11.11.1-0.90.91.01.01.00.90.90.0
Patch foraging water rate 0 sec0.40.71.1-0.9-0.9-0.9-0.9-0.90.9-0.9-0.9-0.9-0.9-0.90.9-0.9-1.0-1.0-0.9-0.3-0.90.0
Patch foraging water rate 12 sec0.51.01.1-1.0-1.0-1.0-1.0-1.01.0-1.0-1.0-1.0-1.0-1.01.0-1.0-1.1-1.1-1.0-0.2-1.00.0
Patch foraging water rate 18 sec2.33.54.0-2.0-2.0-2.0-2.0-2.02.0-2.0-2.0-2.0-2.0-2.01.9-1.9-1.8-1.8-1.9-1.6-1.80.0
Patch foraging water rate 24 sec0.10.20.2-0.4-0.4-0.4-0.4-0.40.4-0.4-0.4-0.4-0.4-0.40.4-0.4-0.3-0.3-0.4-0.5-0.30.0
Patch foraging water rate 6 sec2.33.34.0-1.9-1.9-1.9-1.9-1.91.9-1.9-1.9-1.9-1.9-1.91.8-1.8-2.0-2.0-1.9-1.3-1.80.0
Seeking ratio, delayed vs. immediate footshock0.60.82.60.80.90.90.90.9-0.90.90.90.80.80.8-0.60.61.01.00.81.60.70.0
Distance traveled before self-admin0.60.70.9-0.9-0.9-0.9-0.9-0.90.9-0.9-0.9-0.9-0.9-0.91.0-1.0-0.8-0.8-0.9-0.6-0.90.0
Distance traveled after self-admin2.53.16.8-1.8-1.9-1.9-1.9-1.81.8-1.9-1.9-1.8-1.8-1.81.7-1.7-1.3-1.3-1.8-2.6-1.60.0
Extensor digitorum longus weight12.247.855.4-7.4-7.2-7.2-7.2-7.27.2-7.2-7.2-7.2-7.2-7.27.1-7.1-7.1-7.1-7.1-6.0-7.10.0
Bone: elastic displacement0.30.31.00.60.60.60.60.6-0.60.60.60.60.60.6-0.50.50.40.40.61.00.50.0
Bone: elastic work0.20.20.30.50.50.50.50.5-0.50.50.50.50.50.5-0.50.50.50.50.50.50.50.0
Bone: endosteal estimation0.00.00.5-0.0-0.2-0.1-0.1-0.10.1-0.1-0.1-0.1-0.1-0.1-0.10.10.00.0-0.0-0.70.10.0
Bone: endosteal perimeter0.00.00.1-0.0-0.2-0.1-0.1-0.10.1-0.1-0.1-0.1-0.1-0.1-0.10.1-0.1-0.1-0.1-0.20.00.0
Epididymis fat weight0.72.53.21.71.61.61.61.6-1.61.61.61.61.61.6-1.81.81.71.71.60.41.80.0
Delta time in closed arm before/after self-admin2.92.74.11.71.71.71.71.7-1.71.71.71.71.71.7-1.71.71.51.51.72.01.60.0
Delta time in open arm before/after self-admin0.00.00.3-0.1-0.1-0.1-0.1-0.10.1-0.1-0.1-0.1-0.1-0.10.1-0.1-0.5-0.5-0.10.5-0.20.0
Diff in mean of infusions in LGA sessions0.50.63.2-0.7-0.8-0.8-0.8-0.80.8-0.8-0.8-0.7-0.7-0.70.6-0.6-0.4-0.4-0.7-1.8-0.60.0
Delay discount exponential model param0.40.50.60.70.70.70.70.7-0.70.70.70.70.70.7-0.70.70.70.70.70.70.70.0
Extinction: sum of active levers before priming1.92.13.71.61.41.41.41.4-1.41.41.41.41.41.4-1.61.61.91.91.40.11.70.0
Active lever presses in extinction session 60.30.31.10.50.50.50.50.5-0.50.50.50.50.50.5-0.50.51.01.00.5-0.50.60.0
Bone: final force0.00.10.4-0.2-0.3-0.3-0.3-0.30.3-0.3-0.3-0.2-0.2-0.20.1-0.1-0.1-0.1-0.2-0.6-0.10.0
Bone: final moment0.00.00.5-0.1-0.2-0.2-0.2-0.20.2-0.2-0.2-0.1-0.1-0.10.0-0.00.10.1-0.1-0.70.00.0
Food consumed during 24 hour testing period0.30.50.70.80.60.60.60.6-0.60.60.60.70.70.7-0.90.90.80.80.70.10.80.0
Glucose0.00.00.10.20.00.10.10.1-0.10.10.10.10.10.1-0.20.20.10.10.1-0.10.20.0
Heart weight0.61.01.51.10.91.01.01.0-1.01.01.01.01.01.0-1.21.21.01.01.00.31.20.0
Delay discount hyperbolic model param0.50.60.70.80.80.80.80.8-0.80.80.80.80.80.8-0.80.80.80.80.80.70.80.0
Intermittent access intake day 1-15 change1.73.55.52.01.91.91.91.9-1.91.91.91.91.91.9-1.91.91.71.71.92.31.90.0
Intermittent access intake escalation1.83.65.92.01.91.91.91.9-1.91.91.92.02.01.9-2.02.01.71.71.92.41.90.0
Intermittent access intake escalation 21.51.84.01.41.31.31.31.3-1.31.31.31.31.31.3-1.41.41.11.11.32.01.30.0
Intermitt. access day 1 inactive lever presses0.00.00.00.10.10.10.10.1-0.10.10.10.10.10.1-0.10.10.10.10.10.10.20.0
Intermitt. access day 15 inactive lever presses0.00.00.10.20.20.20.20.2-0.20.20.20.20.20.2-0.20.20.00.00.20.10.20.0
Intermitt. access escalation Index0.10.10.3-0.2-0.2-0.2-0.2-0.20.2-0.2-0.2-0.2-0.2-0.20.2-0.2-0.5-0.5-0.2-0.2-0.20.0
Intermittent access day 1 total infusions0.00.00.30.00.00.00.00.0-0.00.00.00.00.00.0-0.10.10.10.10.1-0.50.10.0
Intermittent access day 15 total infusions1.62.42.81.71.61.61.61.6-1.61.61.61.61.61.6-1.61.61.51.51.61.61.60.0
Intermittent access terminal intake (last 3 days)1.01.41.91.31.21.21.21.2-1.21.21.21.21.21.2-1.31.31.01.01.21.41.20.0
Intermittent access total infusions1.11.41.81.31.21.21.21.2-1.21.21.21.21.21.2-1.21.21.31.31.20.61.20.0
Intermittent access day 1 locomotion0.00.00.10.10.10.10.10.1-0.10.10.10.10.10.1-0.10.10.10.10.1-0.30.10.0
Intermittent access day 15 total locomotion0.20.40.50.70.60.60.60.6-0.60.60.60.60.60.6-0.70.70.70.70.60.50.60.0
Intermittent access total locomotion0.10.10.20.40.30.30.30.3-0.30.30.30.30.30.3-0.40.40.40.40.40.20.40.0
Intermittent access standard deviation0.20.30.80.60.50.60.60.6-0.60.60.60.60.60.6-0.60.60.50.50.60.90.60.0
Left kidney weight0.00.10.9-0.3-0.3-0.3-0.3-0.30.3-0.3-0.3-0.3-0.3-0.30.3-0.30.00.0-0.3-0.9-0.20.0
Right kidney weight0.00.10.6-0.1-0.2-0.2-0.2-0.20.2-0.2-0.2-0.2-0.2-0.20.1-0.10.30.3-0.1-0.8-0.10.0
Cocaine induced anxiety0.00.00.0-0.0-0.1-0.1-0.1-0.10.1-0.1-0.1-0.1-0.1-0.1-0.00.0-0.1-0.1-0.00.1-0.00.0
Post-drug Anxiety0.70.81.10.90.90.90.90.9-0.90.90.90.90.90.9-0.80.81.01.00.90.70.90.0
Baseline Anxiety0.30.40.60.60.70.70.70.7-0.70.70.70.70.60.7-0.50.50.80.80.60.40.60.0
Tail length0.41.51.71.31.31.31.31.2-1.21.31.31.21.31.2-1.21.21.31.31.21.31.20.0
Length with tail0.10.20.5-0.5-0.5-0.5-0.5-0.50.5-0.5-0.5-0.5-0.5-0.50.5-0.5-0.2-0.2-0.5-0.7-0.40.0
Length without tail2.16.67.7-2.8-2.7-2.7-2.7-2.72.7-2.7-2.7-2.7-2.7-2.72.7-2.7-2.5-2.5-2.7-2.3-2.60.0
Times rat made contact with spout0.60.70.90.90.80.80.80.8-0.80.80.80.90.90.9-1.01.00.90.90.90.11.00.0
Lifetime Intake0.70.81.41.00.90.90.90.9-0.90.90.90.90.90.9-0.90.91.21.20.90.21.00.0
Liver weight, left1.62.74.2-1.7-1.8-1.7-1.7-1.71.7-1.7-1.7-1.7-1.7-1.71.5-1.5-1.6-1.6-1.7-2.0-1.60.0
Liver weight, right0.61.01.3-1.0-1.0-1.0-1.0-1.01.0-1.0-1.0-1.0-1.0-1.01.0-1.0-1.1-1.1-1.0-0.6-1.00.0
Locomotor activity1.42.22.7-1.6-1.5-1.5-1.5-1.51.5-1.5-1.5-1.5-1.5-1.51.6-1.6-1.6-1.6-1.6-0.8-1.60.0
Locomotor testing distance0.00.10.20.30.30.30.30.3-0.30.30.30.30.30.3-0.20.20.20.20.30.50.30.0
Locomotor testing rearing0.20.30.90.60.60.60.60.6-0.60.60.60.60.60.6-0.40.40.40.40.60.90.50.0
Locomotion in novel chamber0.60.72.20.90.80.80.80.8-0.80.80.80.80.80.8-1.01.00.60.60.81.50.80.0
Locomotion in novel chamber post-restriction0.71.11.4-1.2-1.1-1.1-1.1-1.11.1-1.1-1.1-1.1-1.1-1.11.2-1.2-0.7-0.7-1.1-1.1-1.20.0
Fecal boli incidents, locomotor time 10.60.92.6-0.9-1.0-1.0-1.0-1.01.0-1.0-1.0-1.0-1.0-1.00.9-0.9-0.7-0.7-1.0-1.6-0.80.0
Change in fecal boli incidents, locomotor task0.20.20.4-0.6-0.5-0.5-0.5-0.50.5-0.5-0.5-0.5-0.5-0.50.6-0.6-0.5-0.5-0.50.0-0.60.0
Time >=10cm from walls, locomotor time 11.21.21.51.21.11.21.11.2-1.21.21.11.21.21.2-1.21.21.21.21.20.41.20.0
Bouts of movement, locomotor time 14.85.46.1-2.5-2.4-2.4-2.4-2.42.4-2.4-2.4-2.4-2.4-2.42.4-2.4-2.3-2.3-2.4-2.3-2.30.0
Total resting periods, locomotor time 14.85.36.3-2.4-2.4-2.4-2.4-2.42.4-2.4-2.4-2.4-2.4-2.42.3-2.3-2.2-2.2-2.4-2.5-2.30.0
Rest time, locomotor task time 12.02.42.7-1.7-1.6-1.6-1.6-1.61.6-1.6-1.6-1.6-1.6-1.61.6-1.6-1.6-1.6-1.6-1.5-1.60.0
Distance moved, locomotor task time 11.72.63.11.71.71.71.71.7-1.71.71.71.71.71.7-1.61.61.51.51.61.71.60.0
Vertical activity count, locomotor time 10.30.84.40.80.90.90.90.9-0.90.90.90.80.80.8-0.70.70.40.40.82.10.60.0
Time >=10cm from walls, locomotor time 20.30.41.0-0.6-0.7-0.7-0.7-0.70.7-0.7-0.7-0.7-0.7-0.70.6-0.6-0.5-0.5-0.6-1.0-0.60.0
Bouts of movement, locomotor time 22.94.66.7-2.2-2.3-2.2-2.2-2.22.2-2.2-2.2-2.2-2.2-2.22.1-2.1-1.9-1.9-2.2-2.6-2.10.0
Total resting periods, locomotor time 22.84.97.0-2.3-2.3-2.3-2.3-2.32.3-2.3-2.3-2.3-2.3-2.32.2-2.2-2.0-2.0-2.3-2.7-2.10.0
Rest time, locomotor task time 20.91.11.3-1.2-1.1-1.1-1.1-1.11.1-1.1-1.1-1.1-1.1-1.11.0-1.0-1.1-1.1-1.1-0.7-1.10.0
Distance moved, locomotor task time 22.32.83.31.81.71.71.71.7-1.71.71.71.71.71.7-1.71.71.71.71.71.41.70.0
Vertical activity count, locomotor time 20.20.30.70.60.60.60.60.6-0.60.60.60.60.60.6-0.60.60.50.50.60.80.50.0
Light reinforcement 11.94.76.12.32.32.32.32.3-2.32.32.32.22.22.2-2.12.12.02.02.22.52.10.0
Light reinforcement 20.91.41.61.21.21.21.21.2-1.21.21.21.21.21.2-1.21.21.11.11.21.31.20.0
Bone: marrow area0.00.00.40.1-0.0-0.0-0.00.0-0.0-0.0-0.00.00.10.0-0.20.20.10.10.1-0.60.20.0
Bone: maximum diameter0.20.40.7-0.7-0.7-0.7-0.7-0.70.7-0.7-0.7-0.7-0.7-0.70.6-0.6-0.6-0.6-0.7-0.8-0.60.0
Bone: maximum force0.20.30.8-0.5-0.6-0.6-0.6-0.60.6-0.6-0.6-0.5-0.5-0.50.4-0.4-0.4-0.4-0.5-0.9-0.40.0
Bone: maximum moment0.10.20.8-0.3-0.4-0.4-0.4-0.40.4-0.4-0.4-0.4-0.4-0.40.2-0.2-0.1-0.1-0.4-0.9-0.20.0
Mean time between licks in bursts1.02.42.81.61.61.61.61.6-1.61.61.61.61.61.6-1.61.61.71.71.61.41.60.0
Mean num. licks in bursts0.30.50.70.70.70.70.70.7-0.70.70.70.70.70.7-0.70.70.80.80.70.30.70.0
Cd content in liver1.21.41.6-1.3-1.2-1.2-1.2-1.21.2-1.2-1.2-1.2-1.2-1.21.2-1.2-1.1-1.1-1.2-1.0-1.20.0
Co content in liver4.75.46.8-2.5-2.4-2.4-2.4-2.42.4-2.4-2.4-2.4-2.4-2.42.3-2.3-2.2-2.2-2.4-2.6-2.30.0
Cu content in liver0.50.50.6-0.8-0.8-0.8-0.8-0.80.8-0.8-0.8-0.8-0.8-0.80.8-0.8-0.7-0.7-0.8-0.8-0.70.0
Fe content in liver1.72.02.51.51.51.51.51.5-1.51.51.51.51.51.5-1.51.51.61.61.51.01.50.0
K content in liver1.01.02.51.01.11.11.11.0-1.01.11.11.01.01.0-0.80.80.80.81.01.60.80.0
Mg content in liver2.12.23.61.51.61.61.61.5-1.51.61.61.51.51.5-1.31.31.31.31.51.91.30.0
Mn content in liver2.32.53.01.71.61.61.61.6-1.61.61.61.61.61.6-1.71.71.51.51.61.51.60.0
Na content in liver1.21.31.5-1.2-1.2-1.2-1.2-1.21.2-1.2-1.2-1.2-1.2-1.21.2-1.2-1.1-1.1-1.2-1.2-1.10.0
Rb content in liver0.00.00.20.10.20.20.20.2-0.20.20.20.20.20.2-0.10.10.10.10.20.50.10.0
Se content in liver0.91.01.61.11.11.11.11.1-1.11.11.11.01.01.0-1.01.00.90.91.01.30.90.0
Sr content in liver0.00.00.10.10.00.00.00.0-0.10.00.00.00.00.0-0.10.1-0.0-0.00.00.30.00.0
Zn content in liver0.10.10.20.30.30.30.30.3-0.30.30.30.30.30.3-0.30.30.50.50.30.00.30.0
Bone: minimum diameter0.00.10.5-0.2-0.3-0.3-0.3-0.30.3-0.3-0.3-0.3-0.3-0.30.1-0.1-0.2-0.2-0.3-0.7-0.10.0
Time in familiar zone, hab. session 10.00.00.1-0.1-0.1-0.1-0.1-0.10.1-0.1-0.1-0.1-0.1-0.10.0-0.0-0.0-0.0-0.1-0.4-0.10.0
Time in novel zone, hab. session 11.21.21.4-1.1-1.2-1.2-1.2-1.21.2-1.2-1.2-1.2-1.2-1.21.1-1.1-1.1-1.1-1.2-0.8-1.10.0
Total zone transitions, hab. session 10.30.42.3-0.5-0.6-0.6-0.6-0.60.6-0.6-0.6-0.6-0.6-0.60.4-0.4-0.2-0.2-0.6-1.5-0.30.0
Total locomotion distance, hab. session 10.00.00.50.0-0.1-0.0-0.1-0.00.0-0.0-0.1-0.0-0.0-0.0-0.10.10.30.30.0-0.70.10.0
Locomotion velocity, hab. session 10.10.10.30.30.30.30.30.3-0.30.30.30.30.30.3-0.40.40.60.60.3-0.50.40.0
Time in familiar zone, hab. session 21.71.84.5-1.4-1.4-1.4-1.4-1.41.4-1.4-1.4-1.3-1.3-1.31.2-1.2-1.2-1.2-1.3-2.1-1.20.0
Time in novel zone, hab. session 20.60.61.80.80.80.80.80.8-0.80.80.80.80.80.8-0.70.70.70.70.81.30.70.0
Total zone transitions, hab. session 21.72.12.5-1.6-1.5-1.5-1.5-1.51.5-1.5-1.5-1.5-1.5-1.51.6-1.6-1.3-1.3-1.5-1.4-1.50.0
Total locomotion distance, hab. session 20.40.60.8-0.9-0.8-0.8-0.8-0.80.8-0.8-0.8-0.8-0.8-0.80.9-0.9-0.6-0.6-0.8-0.7-0.80.0
Locomotion velocity, hab. session 20.81.11.3-1.2-1.1-1.1-1.1-1.11.1-1.1-1.1-1.1-1.1-1.11.1-1.1-0.9-0.9-1.1-1.0-1.10.0
Novel to familiar place preference ratio1.21.34.01.11.31.21.21.2-1.21.21.21.11.11.2-0.90.90.90.91.12.00.90.0
Novelty place preference0.91.03.61.01.11.11.11.0-1.01.11.11.01.01.0-0.80.80.80.81.01.90.80.0
Time in novel zone, NPP test0.50.52.50.60.80.70.70.7-0.70.70.70.70.70.7-0.50.50.50.50.61.60.50.0
Total zone transitions, NPP test0.10.10.20.30.30.30.30.3-0.30.30.30.30.30.3-0.30.30.50.50.3-0.30.30.0
Total locomotion distance, NPP test2.12.93.51.81.71.71.71.7-1.71.71.71.71.71.7-1.81.81.91.91.81.11.80.0
Locomotion velocity, NPP test2.02.83.41.81.71.71.71.7-1.71.71.71.71.71.7-1.81.81.81.81.71.11.80.0
Intraocular pressure0.50.71.11.00.80.80.80.9-0.90.80.80.90.90.9-1.01.00.90.90.90.61.00.0
Delta distance traveled before/after self-admin3.23.46.4-1.9-1.9-1.9-1.9-1.91.9-1.9-1.9-1.9-1.9-1.91.8-1.8-1.5-1.5-1.9-2.5-1.70.0
Delta ambulatory time before/after self-admin2.83.57.0-2.0-2.0-2.0-2.0-1.91.9-2.0-2.0-1.9-1.9-1.91.8-1.8-1.5-1.5-1.9-2.6-1.70.0
Parametrial fat weight2.25.18.72.42.32.32.32.3-2.32.32.32.32.32.3-2.32.33.03.02.30.92.40.0
Pavlov. Cond. lever latency0.00.00.00.10.10.10.10.1-0.10.10.10.10.10.1-0.20.20.10.10.1-0.00.20.0
Pavlov. Cond. magazine entry latency0.10.10.20.30.20.20.20.3-0.30.20.20.30.30.3-0.40.40.40.40.3-0.40.40.0
Pavlov. Cond. change in total contacts1.21.31.6-1.2-1.1-1.1-1.1-1.11.1-1.1-1.1-1.2-1.2-1.21.2-1.2-1.0-1.0-1.2-1.2-1.20.0
Pavlov. Cond. index score0.10.10.1-0.4-0.3-0.3-0.3-0.30.3-0.3-0.3-0.3-0.3-0.30.3-0.3-0.3-0.3-0.3-0.4-0.30.0
Pavlov. Cond. latency score0.00.00.1-0.2-0.2-0.2-0.2-0.20.2-0.2-0.2-0.2-0.2-0.20.2-0.2-0.1-0.1-0.2-0.4-0.20.0
Pavlov. Cond. lever contacts0.00.00.0-0.00.00.00.00.0-0.00.00.00.0-0.00.00.1-0.10.10.1-0.0-0.1-0.10.0
Pavlov. Cond. magazine entry number0.30.31.30.60.60.60.60.6-0.60.60.60.60.60.6-0.50.50.40.40.61.10.40.0
Pavlov. Cond. intertrial magazine entries0.10.10.20.40.30.30.30.3-0.30.30.30.30.30.3-0.40.40.50.50.3-0.10.40.0
Pavlov. Cond. lever-magazine prob. diff.0.20.20.4-0.5-0.5-0.5-0.5-0.50.5-0.5-0.5-0.5-0.5-0.50.5-0.5-0.4-0.4-0.5-0.6-0.50.0
Pavlov. Cond. response bias0.10.20.7-0.4-0.4-0.4-0.4-0.40.4-0.4-0.4-0.4-0.4-0.40.4-0.4-0.2-0.2-0.4-0.8-0.30.0
Pavlov. Cond. lever latency0.50.71.30.90.80.80.80.8-0.80.80.80.80.80.8-0.90.91.11.10.80.20.90.0
Pavlov. Cond. magazine entry latency0.00.00.20.20.20.20.20.2-0.20.20.20.20.20.2-0.20.2-0.0-0.00.20.50.20.0
Pavlov. Cond. change in total contacts1.21.92.5-1.5-1.4-1.4-1.4-1.41.4-1.4-1.4-1.4-1.4-1.41.4-1.4-1.6-1.6-1.4-1.0-1.40.0
Pavlov. Cond. index score0.50.61.2-0.8-0.8-0.8-0.8-0.80.8-0.8-0.8-0.8-0.8-0.80.8-0.8-1.1-1.1-0.8-0.4-0.80.0
Pavlov. Cond. latency score0.30.40.8-0.7-0.7-0.6-0.6-0.60.6-0.6-0.6-0.6-0.6-0.60.6-0.6-0.9-0.9-0.6-0.3-0.70.0
Pavlov. Cond. lever contacts0.30.40.8-0.7-0.6-0.6-0.6-0.60.6-0.6-0.6-0.6-0.6-0.60.6-0.6-0.9-0.9-0.6-0.1-0.70.0
Pavlov. Cond. magazine entry number0.00.00.2-0.0-0.1-0.1-0.1-0.10.1-0.1-0.1-0.1-0.1-0.10.0-0.00.20.2-0.0-0.40.00.0
Pavlov. Cond. intertrial magazine entries5.38.09.33.12.92.92.92.9-2.92.92.92.92.92.9-3.03.03.03.02.91.93.00.0
Pavlov. Cond. lever-magazine prob. diff.0.60.81.3-0.9-0.9-0.9-0.9-0.90.9-0.9-0.9-0.9-0.9-0.90.9-0.9-1.2-1.2-0.9-0.5-0.90.0
Pavlov. Cond. response bias0.40.51.0-0.8-0.6-0.6-0.6-0.70.7-0.6-0.6-0.7-0.7-0.70.7-0.7-1.0-1.0-0.70.0-0.80.0
Time in closed arm before self-admin1.01.32.5-1.3-1.1-1.1-1.1-1.11.1-1.1-1.1-1.1-1.2-1.21.2-1.2-0.9-0.9-1.1-1.6-1.20.0
Time in closed arm after self-admin0.00.00.1-0.1-0.0-0.0-0.0-0.00.0-0.0-0.0-0.0-0.0-0.00.1-0.10.10.1-0.0-0.2-0.10.0
Time in open arm before self-admin0.00.00.2-0.1-0.2-0.2-0.2-0.20.2-0.2-0.2-0.2-0.2-0.20.1-0.10.10.1-0.1-0.5-0.10.0
Time in open arm after self-admin0.00.00.20.10.00.00.00.0-0.00.00.00.00.10.1-0.10.1-0.2-0.20.10.50.10.0
Bone: periosteal estimation0.00.00.30.0-0.1-0.1-0.1-0.10.1-0.1-0.1-0.0-0.0-0.0-0.10.10.10.1-0.0-0.60.10.0
Bone: periosteal perimeter0.00.00.0-0.0-0.1-0.1-0.1-0.10.1-0.1-0.1-0.1-0.1-0.1-0.00.0-0.2-0.2-0.10.2-0.00.0
Bone: post-yield work0.20.30.40.60.50.50.50.5-0.50.50.50.50.50.5-0.60.60.60.60.50.10.60.0
Progressive ratio test 1 active lever presses0.10.11.5-0.2-0.2-0.2-0.2-0.20.2-0.2-0.2-0.2-0.2-0.20.2-0.2-0.1-0.1-0.2-1.2-0.20.0
Progressive ratio test 1 breakpoint0.10.21.8-0.3-0.3-0.3-0.3-0.30.3-0.3-0.3-0.3-0.3-0.30.3-0.3-0.1-0.1-0.3-1.3-0.20.0
Progressive ratio test 1 inactive lever presses0.81.21.51.21.11.11.11.1-1.11.11.11.21.21.2-1.21.21.11.11.20.51.20.0
Progressive ratio test 2 active lever presses0.10.10.80.20.10.10.10.1-0.10.10.10.10.10.1-0.20.20.70.70.1-0.90.30.0
Progressive ratio test 2 breakpoint0.10.10.80.20.10.10.10.1-0.10.10.10.10.10.1-0.20.20.70.70.1-0.90.30.0
Progressive ratio test 2 inactive lever presses0.30.51.30.70.60.60.60.6-0.60.60.60.60.60.6-0.70.71.21.20.7-0.20.70.0
Incentive Sensitization - Responses0.20.31.10.60.50.50.50.5-0.50.50.50.50.50.5-0.60.61.11.10.5-0.10.60.0
Incentive Sensitization - Breakpoint0.30.41.30.70.60.60.60.6-0.60.60.60.60.60.6-0.70.71.11.10.60.00.70.0
Sum of active levers in priming session hrs 5-60.10.10.70.20.10.10.10.1-0.10.10.10.10.10.1-0.30.30.60.60.2-0.90.30.0
Progressive ratio0.20.31.6-0.4-0.3-0.3-0.3-0.30.3-0.3-0.3-0.3-0.3-0.30.5-0.5-0.8-0.8-0.41.3-0.50.0
Food seeking constrained by brief footshock1.82.22.6-1.6-1.6-1.6-1.6-1.61.6-1.6-1.6-1.6-1.6-1.61.3-1.3-1.5-1.5-1.5-1.4-1.50.0
Seeking ratio, punishment vs. effort0.50.75.3-0.7-0.8-0.8-0.8-0.80.8-0.8-0.8-0.7-0.7-0.70.4-0.4-0.1-0.1-0.7-2.3-0.50.0
Retroperitoneal fat weight0.10.61.40.80.70.70.70.7-0.70.70.70.80.80.8-0.90.91.21.20.8-0.40.90.0
Reaction time number correct0.50.92.1-0.9-1.1-1.0-1.0-1.01.0-1.0-1.0-1.0-1.0-1.00.9-0.9-0.8-0.8-1.0-1.5-0.80.0
Reaction time mean minus median0.10.31.0-0.5-0.6-0.6-0.6-0.60.6-0.6-0.6-0.6-0.6-0.60.5-0.5-0.5-0.5-0.6-1.0-0.50.0
Reaction time mean minus median AUC0.10.30.6-0.5-0.5-0.5-0.5-0.50.5-0.5-0.5-0.5-0.5-0.50.5-0.5-0.5-0.5-0.5-0.8-0.50.0
Reaction time num false alarms0.10.12.1-0.0-0.2-0.2-0.2-0.10.1-0.2-0.2-0.1-0.1-0.1-0.10.10.40.4-0.1-1.40.20.0
Reaction time num false alarms AUC0.10.11.50.1-0.1-0.1-0.1-0.00.0-0.1-0.1-0.0-0.0-0.0-0.10.10.40.40.0-1.20.20.0
Reaction time trials correct on left0.50.92.1-0.9-1.1-1.0-1.0-1.01.0-1.0-1.0-1.0-1.0-1.00.9-0.9-0.8-0.8-1.0-1.5-0.80.0
Reaction time trials on left0.40.71.8-0.8-0.9-0.9-0.9-0.90.9-0.9-0.9-0.9-0.8-0.90.7-0.7-0.7-0.7-0.8-1.4-0.70.0
Reaction time mean0.30.50.8-0.7-0.7-0.7-0.7-0.70.7-0.7-0.7-0.7-0.7-0.70.7-0.7-0.6-0.6-0.7-0.9-0.60.0
Reaction time mean AUC0.50.80.9-0.9-0.9-0.9-0.9-0.90.9-0.9-0.9-0.9-0.9-0.90.9-0.9-0.9-0.9-0.9-0.9-0.90.0
Median of all reaction times0.30.40.5-0.7-0.7-0.7-0.7-0.70.7-0.7-0.7-0.7-0.7-0.70.7-0.7-0.6-0.6-0.7-0.6-0.60.0
Reaction time omissions1.62.32.81.71.61.61.61.6-1.61.61.61.61.61.6-1.61.61.41.41.61.61.50.0
Reaction time false alarm rate0.20.30.70.50.50.50.50.5-0.50.50.50.50.50.5-0.60.60.90.90.5-0.40.60.0
Reaction time premature initiation rate1.52.12.4-1.6-1.5-1.5-1.6-1.51.5-1.5-1.6-1.5-1.5-1.51.5-1.5-1.3-1.3-1.5-1.4-1.50.0
Reaction time premature initiations1.83.24.1-1.9-1.9-1.9-1.9-1.91.9-1.9-1.9-1.9-1.9-1.91.8-1.8-1.6-1.6-1.9-2.0-1.70.0
Std. dev. reaction times0.20.41.7-0.6-0.6-0.6-0.6-0.60.6-0.6-0.6-0.6-0.6-0.60.5-0.5-0.3-0.3-0.6-1.3-0.50.0
Reaction time trials completed0.40.71.8-0.8-0.9-0.9-0.9-0.90.9-0.9-0.9-0.9-0.8-0.90.7-0.7-0.7-0.7-0.8-1.4-0.70.0
Reaction time trials AUC0.30.71.7-0.8-0.9-0.9-0.9-0.80.8-0.9-0.9-0.8-0.8-0.80.7-0.7-0.6-0.6-0.8-1.3-0.60.0
Run reversals in cocaine runway, females2.82.83.41.81.71.81.81.8-1.81.81.81.81.81.8-1.81.81.61.61.81.31.70.0
Run reversals in cocaine runway, males1.81.82.0-1.4-1.4-1.4-1.4-1.41.4-1.4-1.4-1.4-1.4-1.41.3-1.3-1.4-1.4-1.4-1.1-1.30.0
Latency to leave start box in cocaine runway1.01.12.7-1.0-0.8-0.9-0.9-0.90.9-0.9-0.9-0.9-0.9-0.91.1-1.1-1.6-1.6-1.01.3-1.20.0
Latency to leave start box in cocaine runway, F2.22.55.1-1.6-1.4-1.4-1.4-1.51.5-1.4-1.4-1.5-1.5-1.51.8-1.8-2.3-2.3-1.61.0-1.80.0
Latency to leave start box in cocaine runway, M0.10.10.20.40.30.30.30.3-0.30.30.30.30.30.3-0.40.40.20.20.30.30.40.0
Std. dev. time between licks in bursts1.52.13.01.61.41.41.41.5-1.51.41.41.51.51.5-1.61.61.71.71.50.41.60.0
Total sessions with >9 infusions0.00.10.8-0.1-0.2-0.2-0.2-0.20.2-0.2-0.2-0.1-0.1-0.10.1-0.10.10.1-0.1-0.9-0.00.0
Short access day 1 total inactive lever presses0.10.20.40.40.40.40.40.4-0.40.40.40.40.40.4-0.40.40.60.60.4-0.10.40.0
Short access day 10 total inactive lever presses0.10.21.10.50.50.50.50.5-0.50.50.50.40.40.4-0.40.40.30.30.41.00.40.0
Short access day 1 total infusions0.10.10.6-0.3-0.3-0.3-0.3-0.30.3-0.3-0.3-0.3-0.3-0.30.3-0.3-0.1-0.1-0.3-0.8-0.30.0
Short access day 10 total infusions0.20.30.5-0.6-0.6-0.6-0.6-0.60.6-0.6-0.6-0.6-0.6-0.60.5-0.5-0.6-0.6-0.6-0.7-0.60.0
Short access total infusions0.10.10.9-0.2-0.2-0.2-0.2-0.20.2-0.2-0.2-0.2-0.2-0.20.2-0.20.00.0-0.2-1.0-0.10.0
Short access day 1 locomotion0.81.01.2-1.1-1.0-1.0-1.0-1.01.0-1.0-1.0-1.0-1.0-1.01.0-1.0-0.9-0.9-1.0-1.1-1.00.0
Short access day 10 total locomotion0.00.00.00.10.20.20.20.2-0.20.20.20.20.20.2-0.20.20.00.00.20.20.10.0
Short access total locomotion0.10.10.2-0.3-0.3-0.3-0.3-0.30.3-0.3-0.3-0.3-0.3-0.30.2-0.2-0.4-0.4-0.3-0.3-0.30.0
One hour access (0.3 mA shock)0.70.81.41.00.90.90.90.9-0.90.90.90.90.90.9-0.90.91.21.20.90.41.00.0
Compulsive drug intake0.50.60.90.80.80.80.80.8-0.80.80.80.80.80.8-0.70.71.01.00.80.60.70.0
One hour access (shock baseline)0.00.00.10.10.00.00.00.0-0.00.00.00.00.00.0-0.10.10.30.30.0-0.20.10.0
Social response proportion0.20.20.3-0.5-0.4-0.5-0.5-0.50.5-0.5-0.5-0.5-0.5-0.50.5-0.5-0.3-0.3-0.5-0.5-0.50.0
Social responses1.01.31.71.31.11.11.11.2-1.21.11.11.21.21.2-1.31.31.21.21.20.71.30.0
Social time0.20.31.30.40.60.60.60.5-0.50.60.60.50.50.5-0.20.20.20.20.51.10.30.0
Soleus weight1.13.33.7-1.9-1.9-1.9-1.9-1.91.9-1.9-1.9-1.9-1.9-1.91.8-1.8-1.9-1.9-1.8-1.8-1.80.0
Bone: stiffness0.50.81.4-0.9-1.0-1.0-1.0-1.01.0-1.0-1.0-0.9-0.9-0.90.8-0.8-0.7-0.7-0.9-1.2-0.80.0
Tibialis anterior weight8.027.031.0-5.6-5.4-5.4-5.4-5.45.4-5.4-5.4-5.4-5.4-5.45.3-5.3-5.3-5.3-5.4-4.6-5.30.0
Time to tail flick, vehicle, before self-admin1.01.11.31.11.11.11.11.1-1.11.11.11.11.11.1-1.11.11.21.21.10.31.10.0
Time to tail flick, vehicle, after self-admin1.41.92.7-1.5-1.3-1.3-1.3-1.31.3-1.3-1.3-1.4-1.4-1.41.6-1.6-1.7-1.7-1.4-0.9-1.60.0
Time to tail flick, test, before self-admin3.03.14.41.91.81.81.81.8-1.81.81.81.81.81.8-1.91.92.12.11.80.72.00.0
Time to tail flick, test, after self-admin2.12.23.11.61.61.61.61.5-1.51.61.51.51.51.5-1.41.41.81.81.50.71.50.0
Delta time to tail flick, vehicle, before/after SA0.40.40.9-0.7-0.5-0.6-0.6-0.60.6-0.6-0.6-0.6-0.6-0.60.8-0.8-0.9-0.9-0.60.4-0.80.0
Delta time to tail flick, test, before/after SA0.00.00.1-0.00.10.10.10.0-0.10.10.10.00.00.00.1-0.1-0.1-0.10.00.2-0.10.0
Tibia length1.13.03.41.81.81.81.81.8-1.81.81.81.81.81.8-1.71.71.81.81.81.71.70.0
Ambulatory time before self-admin0.10.20.3-0.5-0.5-0.5-0.5-0.50.5-0.5-0.5-0.5-0.5-0.50.5-0.5-0.5-0.5-0.50.1-0.50.0
Ambulatory time after self-admin5.15.98.7-2.6-2.6-2.6-2.6-2.62.6-2.6-2.6-2.6-2.6-2.52.5-2.5-2.0-2.0-2.5-2.9-2.40.0
Bone: tissue strength0.10.10.20.40.30.30.30.4-0.40.30.30.40.40.4-0.40.40.40.40.4-0.00.40.0
Total heroin consumption0.60.72.3-0.8-0.8-0.8-0.8-0.80.8-0.8-0.8-0.8-0.8-0.80.8-0.8-0.5-0.5-0.8-1.5-0.80.0
Bone: trabecular number2.44.04.62.22.12.12.12.1-2.12.12.12.12.12.1-2.02.02.12.12.01.72.00.0
Bone: trabecular spacing2.23.03.5-1.9-1.8-1.8-1.8-1.81.8-1.8-1.8-1.8-1.8-1.81.8-1.8-1.9-1.9-1.8-1.2-1.80.0
Bone: trabecular thickness1.01.31.61.21.21.21.21.2-1.21.21.21.21.21.2-1.21.21.31.31.20.61.20.0
Bone: trabecular tissue density1.32.03.0-1.5-1.5-1.5-1.5-1.51.5-1.5-1.5-1.5-1.4-1.51.4-1.4-1.2-1.2-1.4-1.7-1.30.0
Water consumed over 24 hours1.11.42.7-1.2-1.3-1.3-1.3-1.31.3-1.3-1.3-1.2-1.2-1.21.0-1.0-1.2-1.2-1.2-1.6-1.00.0
Number of responses in last shaping day0.60.70.8-0.9-0.8-0.8-0.8-0.80.8-0.8-0.8-0.8-0.8-0.80.9-0.9-0.9-0.9-0.8-0.7-0.80.0