Hub : Traits : Tibialis anterior weight : ← : →

chr5:51,803,731-54,764,625

Trait: Tibialis anterior weight

Best TWAS P = 7.26e-09 · Best GWAS P= 7.68e-09 conditioned to 1.96e-01

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	RGD1359108	alternative polyA	XM_039109829.2	0.13	195	0.07	1.8e-08	-5.59	2.23e-08	0.72	FALSE
Adipose	RGD1359108	alternative polyA	XM_039109830.2	0.13	112	0.07	1.8e-08	5.6	2.11e-08	0.72	FALSE
Adipose	Akirin2	alternative TSS	NM_001039914.2	0.02	74	0.01	1.4e-02	5.27	1.34e-07	0.29	FALSE
Adipose	Rars2	alternative TSS	XM_039109436.2	0.04	1	0.03	2.8e-04	5.28	1.27e-07	0.12	FALSE
Adipose	Rars2	alternative TSS	NM_001106643.2	0.02	1	0.01	7.0e-03	-5.27	1.34e-07	0.03	FALSE
Adipose	Rars2	alternative TSS	XM_006237986.5	0.04	1	0.04	7.3e-05	5.28	1.27e-07	0.21	FALSE
Adipose	LOC103692331	gene expression	LOC103692331	0.02	1449	0.01	3.4e-02	5.21	1.91e-07	0.23	FALSE
Adipose	LOC134486926	gene expression	LOC134486926	0.04	1	0.02	3.0e-03	5.26	1.42e-07	0.03	FALSE
Adipose	RGD1359108	gene expression	RGD1359108	0.18	1	0.08	2.3e-09	5.53	3.22e-08	0.74	FALSE
Adipose	Slc35a1	gene expression	Slc35a1	0.1	8	0.06	2.3e-07	5.38	7.48e-08	0.51	FALSE
Adipose	RGD1359108	isoform ratio	XR_010066381.1	0.05	125	0.02	3.6e-03	5.58	2.46e-08	0.62	FALSE
BLA	LOC103692331	gene expression	LOC103692331	0.11	1449	0.1	4.1e-06	5.22	1.75e-07	0.47	FALSE
BLA	LOC134486925	gene expression	LOC134486925	0.65	982	0.28	2.5e-15	5.57	2.61e-08	0.76	FALSE
BLA	RGD1359108	gene expression	RGD1359108	0.12	1	0.07	8.2e-05	5.26	1.42e-07	0.06	FALSE
BLA	Rars2	mRNA stability	Rars2	0.1	1626	0.05	7.5e-04	5.55	2.81e-08	0.49	FALSE
Brain	Rars2	alternative polyA	NM_001106643.2	0.05	1	0.05	1.1e-05	-5.27	1.34e-07	0.31	FALSE
Brain	Rars2	alternative polyA	XM_006237986.5	0.11	32	0.11	1.7e-10	-5.23	1.69e-07	0.49	FALSE
Brain	Rars2	alternative polyA	NM_001106643.2	0.13	1	0.14	7.9e-13	-5.23	1.69e-07	0.58	FALSE
Brain	Rars2	alternative polyA	XM_006237986.5	0.13	1	0.14	4.5e-13	5.23	1.69e-07	0.58	FALSE
Brain	RGD1359108	alternative polyA	XM_039109829.2	0.16	1	0.12	1.4e-11	-5.46	4.70e-08	0.67	FALSE
Brain	RGD1359108	alternative polyA	XM_039109830.2	0.17	1	0.13	4.7e-12	5.46	4.70e-08	0.67	FALSE
Brain	LOC134486925	gene expression	LOC134486925	0.4	10	0.25	9.6e-23	5.47	4.60e-08	0.75	FALSE
Brain	RGD1359108	isoform ratio	XR_010066381.1	0.05	1	0.03	8.6e-04	5.46	4.70e-08	0.05	FALSE
Brain	Rars2	intron excision ratio	chr5_53992191_53993110	0.03	1626	0.02	1.1e-02	-5.51	3.54e-08	0.33	FALSE
Brain	RGD1359108	mRNA stability	RGD1359108	0.07	1	0.05	1.5e-05	-5.53	3.22e-08	0.32	FALSE
Brain	Slc35a1	mRNA stability	Slc35a1	0.09	1	0.06	1.3e-06	-5.33	9.96e-08	0.62	FALSE
IC	Cnr1	gene expression	Cnr1	0.08	3	0.04	1.2e-02	5.23	1.68e-07	0.32	FALSE
IC	LOC103692331	gene expression	LOC103692331	0.2	1449	0.08	3.2e-04	5.3	1.13e-07	0.48	FALSE
IC	LOC120102853	gene expression	LOC120102853	0.08	25	0.02	5.1e-02	5.22	1.78e-07	0.33	FALSE
IC	RGD1359108	isoform ratio	NM_001007702.2	0.1	1	0.06	1.7e-03	-5.78	7.68e-09	0.07	FALSE
IL	Rars2	alternative polyA	XM_006237986.5	0.29	1626	0.12	8.9e-04	-5.48	4.29e-08	0.45	FALSE
IL	Rars2	alternative polyA	NM_001106643.2	0.29	1626	0.12	8.5e-04	5.45	5.05e-08	0.46	FALSE
IL	Rars2	alternative polyA	XM_006237986.5	0.28	1626	0.12	1.0e-03	-5.46	4.85e-08	0.45	FALSE
IL	Cfap206	gene expression	Cfap206	0.42	1	0.19	2.4e-05	5.33	9.96e-08	0.07	FALSE
IL	Rars2	isoform ratio	XM_006237986.5	0.19	1626	0.07	8.8e-03	-5.55	2.82e-08	0.37	FALSE
IL	Rngtt	mRNA stability	Rngtt	0.5	794	0.04	5.0e-02	5.34	9.30e-08	0.27	FALSE
LHb	Cfap206	gene expression	Cfap206	0.67	1	0.4	1.3e-10	5.33	9.96e-08	0.57	FALSE
Liver	RGD1359108	gene expression	RGD1359108	0.04	8	0.01	3.7e-02	5.48	4.34e-08	0.46	FALSE
Liver	Slc35a1	gene expression	Slc35a1	0.12	1621	0.09	7.8e-10	5.27	1.39e-07	0.49	FALSE
Liver	Rars2	intron excision ratio	chr5_53980699_53982440	0.22	1	0.12	2.1e-13	5.23	1.74e-07	0.58	FALSE
Liver	Rars2	intron excision ratio	chr5_53980699_53984117	0.16	1	0.12	6.6e-13	-5.23	1.74e-07	0.58	FALSE
Liver	Rars2	intron excision ratio	chr5_54018938_54029227	0.03	1626	0	1.1e-01	5.47	4.44e-08	0.36	FALSE
NAcc	Rars2	alternative polyA	XM_006237986.5	0.06	1626	0.05	3.4e-08	-5.56	2.65e-08	0.49	FALSE
NAcc	Rars2	alternative polyA	NM_001106643.2	0.05	1626	0.04	1.7e-07	5.56	2.67e-08	0.49	FALSE
NAcc	Rars2	alternative polyA	XM_006237986.5	0.05	1626	0.05	1.1e-07	-5.56	2.75e-08	0.49	FALSE
NAcc	Cfap206	alternative TSS	NM_001079701.1	0.05	1585	0.06	5.6e-09	5.53	3.26e-08	0.43	FALSE
NAcc	Cfap206	alternative TSS	NM_001079701.1	0.05	1585	0.06	4.1e-09	5.51	3.49e-08	0.42	FALSE
NAcc	RGD1359108	alternative TSS	NM_001007702.2	0.03	1080	0.02	4.0e-04	5.68	1.36e-08	0.73	FALSE
NAcc	RGD1359108	alternative TSS	XM_039109829.2	0.04	1	0.03	7.4e-05	5.5	3.79e-08	0.6	FALSE
NAcc	RGD1359108	alternative TSS	NM_001007702.2	0.05	34	0.04	3.4e-06	-5.75	8.92e-09	0.73	FALSE
NAcc	RGD1359108	alternative TSS	XM_039109829.2	0.05	18	0.04	2.7e-06	5.72	1.05e-08	0.72	FALSE
NAcc	Cfap206	gene expression	Cfap206	0.8	132	0.55	7.2e-101	5.23	1.68e-07	0.42	FALSE
NAcc	LOC103692331	gene expression	LOC103692331	0.01	1	0.01	2.2e-03	-5.41	6.39e-08	0.04	FALSE
NAcc	LOC134486925	gene expression	LOC134486925	0.28	37	0.29	6.9e-44	5.54	3.05e-08	0.75	FALSE
NAcc	Cfap206	isoform ratio	XM_017593532.3	0.07	1585	0.08	1.3e-12	-5.51	3.68e-08	0.42	FALSE
NAcc	Rars2	isoform ratio	XM_006237986.5	0.04	1626	0.04	5.4e-07	-5.54	3.01e-08	0.48	FALSE
NAcc	RGD1359108	isoform ratio	NM_001007702.2	0.07	5	0.06	4.4e-09	5.78	7.26e-09	0.73	TRUE
NAcc	RGD1359108	isoform ratio	XM_039109829.2	0.04	2	0.03	2.0e-05	-5.65	1.63e-08	0.71	FALSE
NAcc	Slc35a1	intron excision ratio	chr5_54027121_54027542	0.03	1621	0.02	2.8e-04	5.4	6.85e-08	0.52	FALSE
OFC	LOC103692331	gene expression	LOC103692331	0.14	1	0.06	1.5e-02	-5.41	6.39e-08	0.05	FALSE
PL	Rars2	alternative polyA	XM_006237986.5	0.05	1626	0.04	1.2e-05	-5.52	3.31e-08	0.48	FALSE
PL	Rars2	alternative polyA	NM_001106643.2	0.05	1626	0.05	8.0e-06	5.4	6.65e-08	0.48	FALSE
PL	Rars2	alternative polyA	XM_006237986.5	0.05	1626	0.05	6.2e-06	-5.36	8.26e-08	0.48	FALSE
PL	LOC103692331	gene expression	LOC103692331	0.04	1449	0.06	1.2e-06	5.24	1.65e-07	0.53	FALSE
PL	LOC134486925	gene expression	LOC134486925	0.47	35	0.24	8.2e-26	5.53	3.25e-08	0.77	FALSE
PL	Slc35a1	mRNA stability	Slc35a1	0.04	1621	0.03	4.7e-04	5.5	3.72e-08	0.49	FALSE
pVTA	LOC103692331	gene expression	LOC103692331	0.23	1448	0.04	2.8e-04	5.32	1.03e-07	0.52	FALSE
pVTA	Cfap206	isoform ratio	XM_017593532.3	0.08	7	0.07	2.1e-06	-5.26	1.43e-07	0.44	FALSE
pVTA	RGD1359108	mRNA stability	RGD1359108	0.04	1	0.03	1.2e-03	-5.53	3.22e-08	0.06	FALSE
RMTg	RGD1359108	gene expression	RGD1359108	0.23	11	0.15	9.4e-05	-5.49	4.06e-08	0.67	FALSE
RMTg	Rars2	mRNA stability	Rars2	0.15	4	0.14	1.9e-04	5.35	8.83e-08	0.47	FALSE