chr6:19,297,402-21,124,468

Trait: Tibialis anterior weight

Best TWAS P=7.42e-10 · Best GWAS P=3.91e-10 conditioned to 1.18e-01

Associated models

Tissue Gene RNA modality RNA phenotype h2 # weights Model R2 Model R2 P TWAS Z TWAS P Coloc P Joint
Adipose Rasgrp3 isoform ratio XM_006239762.4 0.05 1 0.04 8.2e-05 -6.16 7.42e-10 0.37 TRUE
Adipose Rasgrp3 intron excision ratio chr6_19968222_19993572 0.04 22 0.01 2.2e-02 -5.26 1.47e-07 0.42 FALSE
BLA Ltbp1 gene expression Ltbp1 0.19 2413 0.17 3.2e-09 -5.26 1.43e-07 0.59 FALSE
BLA Rasgrp3 isoform ratio NM_001399544.1 0.07 10 0.03 1.7e-02 -5.55 2.85e-08 0.51 FALSE
BLA Rasgrp3 intron excision ratio chr6_19935344_19993572 0.15 1 0.08 5.9e-05 -5.19 2.12e-07 0.04 FALSE
Brain Ltbp1 gene expression Ltbp1 0.53 149 0.43 9.4e-43 5.19 2.13e-07 0.83 FALSE
IL Ltbp1 gene expression Ltbp1 0.32 39 0.24 2.3e-06 -6.06 1.38e-09 0.72 FALSE
OFC Ltbp1 gene expression Ltbp1 0.2 2413 0.13 6.0e-04 -5.78 7.67e-09 0.64 FALSE
PL Rasgrp3 isoform ratio XM_006239759.4 0.04 26 0.02 1.5e-03 -5.77 7.76e-09 0.65 FALSE
PL Rasgrp3 intron excision ratio chr6_19935344_19958446 0.03 2404 0.01 6.8e-02 -5.75 8.90e-09 0.6 FALSE
PL Rasgrp3 mRNA stability Rasgrp3 0.05 1 0.05 7.1e-06 -5.5 3.70e-08 0.08 FALSE
pVTA Fam98a gene expression Fam98a 0.09 66 0.08 1.7e-04 -5.4 6.63e-08 0.32 FALSE
pVTA Ltbp1 gene expression Ltbp1 0.25 6 0.22 9.3e-10 -5.9 3.63e-09 0.82 FALSE