Hub : Genes

Ahnak

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Ahnak 0.09 0.05 2.1e-06 0.01 0.04 0.04 0.03 1.7e-02 5.2e-05 3.0e-05 2.2e-04
2 Adipose isoform ratio NM_001398671.1 0.03 0.02 3.6e-03 0.02 0.01 0.01 0.01 3.5e-03 1.9e-02 2.1e-02 1.5e-02
3 Adipose mRNA stability Ahnak 0.2 0.1 0.0e+00 0.11 0.12 0.1 0.12 1.2e-12 3.3e-13 1.6e-11 1.4e-13
4 Liver alternative polyA XM_017588769.3 0.04 0.03 4.6e-04 0.03 0.02 0.02 0.03 2.4e-04 6.3e-03 9.2e-04 7.5e-04
5 Liver alternative polyA XM_017588769.3 0.04 0.03 9.8e-04 0.03 0.01 0.02 0.03 2.3e-04 7.6e-03 1.6e-03 5.9e-04
6 NAcc isoform ratio NM_001398671.1 0.03 0.02 2.5e-05 0.04 0.04 0.03 0.03 4.6e-06 4.6e-06 5.3e-06 8.2e-06
7 Adipose alternative polyA XM_063278638.1 0.31 0.16 1.6e-05 0.03 0.01 0.01 0.02 3.9e-04 1.1e-02 1.4e-02 4.3e-03
8 Adipose isoform ratio XM_063278638.1 0.07 0.08 1.7e-04 0.03 0.02 0.04 0.02 2.4e-04 1.5e-03 4.9e-05 1.6e-03
9 Adipose alternative polyA XM_017588769.3 0.22 0.15 7.2e-04 0.01 0.01 0.03 0.01 5.0e-02 4.1e-02 6.4e-04 4.3e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.20.40.70.4-0.70.70.80.8-0.50.50.1-0.7
Area under the delay curve0.10.10.5-0.5-0.10.20.10.1-0.10.4-0.7-0.0
BMI with tail1.55.28.11.3-2.82.82.82.8-2.12.7-0.9-1.3
BMI without tail0.41.12.6-0.1-1.31.31.01.0-0.91.6-0.7-0.7
Body weight2.611.216.02.5-4.04.03.83.8-3.43.90.9-2.6
Weight adjusted by age0.60.91.41.2-1.11.11.11.1-1.00.90.00.0
Bone surface1.93.55.02.1-2.12.02.22.2-1.71.61.0-1.4
Bone volume0.81.42.21.5-1.31.31.41.4-0.90.80.5-0.9
Breakpoint value in progressive ratio session2.02.44.52.1-1.61.61.71.7-1.91.20.7-0.3
Number of licking bursts0.10.21.00.2-0.20.1-0.0-0.00.00.21.0-0.7
Context. condit. distance diff. score0.70.82.2-1.50.9-0.7-0.7-0.70.7-0.5-1.4-0.1
Locomotion velocity, session 10.20.31.2-1.10.30.1-0.1-0.10.00.4-0.2-0.9
Locomotion distance, session 10.50.62.4-0.5-0.50.70.60.6-0.61.00.1-1.6
Locomotion velocity, session 21.92.23.11.3-1.81.71.61.6-1.71.70.8-1.0
Locomotion distance, session 20.10.20.5-0.2-0.40.40.30.3-0.60.7-0.1-0.5
Locomotion velocity, session 30.20.30.6-0.4-0.50.60.30.3-0.20.8-0.7-0.6
Locomotion distance, session 30.10.10.4-0.2-0.30.40.20.2-0.20.60.1-0.7
Stereotopy head waving bouts, day 30.60.73.7-1.00.6-0.5-0.5-0.50.6-0.5-1.90.5
Stereotopy head waving duration, day 30.40.52.2-1.00.6-0.5-0.5-0.50.4-0.4-1.50.2
Locomotion velocity, session 70.10.10.5-0.20.1-0.2-0.2-0.20.1-0.2-0.70.1
Locomotion distance, session 70.30.41.8-1.10.4-0.2-0.4-0.40.30.1-1.40.3
Stereotopy head waving bouts, day 70.20.20.40.6-0.40.30.40.4-0.3-0.00.3-0.7
Stereotopy head waving duration, day 71.41.72.11.4-1.41.31.41.4-1.31.11.0-1.2
Locomotion velocity, session 80.10.21.1-1.00.4-0.2-0.3-0.3-0.00.2-0.3-0.1
Locomotion distance, session 80.60.82.0-1.30.8-0.8-0.8-0.80.8-0.6-1.4-0.1
Degree of sensitization distance0.30.31.8-0.70.3-0.3-0.2-0.20.4-0.2-1.40.4
Degree of sensitization stereotypy0.91.02.21.5-1.00.91.01.0-1.00.50.9-0.8
Conditioned locomotion0.50.50.70.6-0.80.80.90.9-0.80.80.3-0.3
Cocaine response after cond. corrected0.81.03.7-1.91.2-0.9-0.7-0.70.8-0.4-0.6-0.6
Cocaine response after cond. not corrected0.50.62.1-1.40.9-0.7-0.6-0.60.7-0.4-0.3-0.5
Cocaine response before conditioning0.50.62.41.5-0.90.70.70.7-0.60.30.80.4
Saline control response3.04.05.81.3-2.22.21.91.9-2.12.41.9-2.0
Bone: connectivity density1.32.13.31.1-1.71.71.81.8-1.41.50.3-0.7
Bone: cortical apparent density0.50.72.30.7-0.40.50.70.7-0.80.31.5-1.1
Bone: cortical area0.91.42.41.5-1.41.31.21.2-1.01.01.1-0.9
Bone: cortical porosity0.10.10.20.30.2-0.2-0.1-0.1-0.2-0.40.00.5
Bone: cortical porosity0.00.00.20.3-0.00.10.10.1-0.4-0.0-0.00.3
Bone: cortical thickness3.55.77.32.1-2.52.52.32.3-2.62.62.7-1.8
Bone: cortical thickness0.60.71.50.1-0.60.70.70.7-0.80.91.2-1.1
Bone: cortical tissue density0.60.92.60.8-0.60.60.80.8-1.00.51.6-1.1
Condit. Reinf. active minus inactive responses1.01.11.41.0-1.11.21.21.2-1.11.00.9-0.7
Condit. Reinf. active-inactive response ratio0.50.60.90.5-0.60.80.80.8-0.80.61.0-0.7
Condit. Reinf. active responses0.70.81.61.3-1.11.01.11.1-0.90.60.2-0.2
Condit. Reinf. inactive responses0.20.20.90.5-0.1-0.1-0.1-0.10.3-0.4-1.00.6
Incentive salience index mean1.11.31.81.0-1.31.31.31.3-1.11.20.8-1.1
Condit. Reinf. lever presses0.81.11.90.8-1.21.21.11.1-0.81.00.8-1.4
Condit. Reinf. active minus inactive responses0.10.20.50.60.2-0.4-0.3-0.30.3-0.70.30.3
Condit. Reinf. active-inactive response ratio0.80.92.00.40.7-0.9-0.7-0.70.9-1.4-1.01.4
Condit. Reinf. active responses0.20.31.20.7-0.40.40.30.3-0.30.21.1-0.8
Condit. Reinf. inactive responses0.70.92.8-0.1-0.60.70.60.6-0.61.11.6-1.7
Condit. Reinf. lever presses1.01.42.11.4-1.41.31.31.3-1.01.01.2-0.8
Condit. Reinf. lever reinforcers received0.40.61.51.0-0.70.60.60.6-0.60.41.2-0.8
Conditioned reinforcement - actives0.30.51.30.80.6-0.7-0.6-0.60.5-1.10.20.9
Conditioned reinforcement - inactives0.10.20.60.60.3-0.3-0.2-0.20.5-0.80.00.4
Conditioned locomotion2.32.94.0-1.71.9-1.8-1.7-1.71.9-2.0-1.11.3
Patch foraging indifference point 0 sec0.40.81.70.5-0.91.00.90.9-0.91.00.5-1.3
Patch foraging indifference point AUC1.52.16.02.5-1.41.31.51.5-1.50.61.5-0.3
Delay disc. indifference point, 0s delay0.60.72.2-1.50.7-0.6-0.7-0.70.7-0.2-1.20.1
Delay disc. indifference point, 16s delay0.10.10.10.3-0.30.30.30.3-0.10.2-0.30.1
Delay disc. indifference point, 2s delay0.30.40.6-0.70.5-0.6-0.5-0.50.7-0.5-0.80.7
Delay disc. indifference point, 24s delay0.10.10.4-0.4-0.30.40.30.3-0.30.60.0-0.6
Delay disc. indifference point, 4s delay0.30.30.9-0.7-0.40.60.40.4-0.51.0-0.5-0.3
Delay disc. indifference point, 8s delay0.40.51.5-1.20.7-0.5-0.7-0.70.5-0.2-1.00.3
Indifference point function ln k2.95.115.5-3.92.5-2.1-2.2-2.22.4-1.3-1.4-0.5
Indifference point function log k2.95.115.5-3.92.5-2.1-2.2-2.22.4-1.3-1.4-0.5
Patch foraging total patch changes 0 sec0.51.02.50.3-0.91.00.90.9-1.01.20.8-1.6
Patch foraging total patch changes 12 sec5.67.39.73.1-2.92.93.03.0-3.12.51.9-1.6
Patch foraging total patch changes 18 sec0.71.12.01.3-0.90.81.01.0-1.00.61.4-0.8
Patch foraging total patch changes 24 sec4.78.010.02.5-3.03.03.23.2-2.92.82.1-2.6
Patch foraging total patch changes 6 sec1.21.92.70.9-1.41.41.51.5-1.41.41.0-1.7
Patch foraging time to switch 0 sec0.20.40.90.7-0.60.50.50.5-0.40.2-0.90.7
Patch foraging water rate 0 sec0.30.71.1-1.00.8-0.7-0.7-0.70.8-0.41.0-1.1
Patch foraging water rate 12 sec1.12.46.6-2.61.7-1.5-1.7-1.71.7-0.7-0.3-0.3
Patch foraging water rate 18 sec0.61.04.8-2.20.7-0.5-0.8-0.80.90.3-0.4-1.0
Patch foraging water rate 24 sec1.21.63.7-1.91.5-1.4-1.4-1.41.3-0.9-0.6-0.0
Patch foraging water rate 6 sec1.21.85.3-2.31.4-1.2-1.5-1.51.4-0.60.2-0.7
Seeking ratio, delayed vs. immediate footshock0.00.00.1-0.1-0.20.20.20.2-0.10.30.4-0.1
Distance traveled before self-admin2.02.64.12.0-1.81.71.81.8-1.51.21.3-1.2
Distance traveled after self-admin0.60.81.31.2-0.70.80.90.9-0.90.51.1-0.8
Extensor digitorum longus weight5.822.829.24.0-5.45.45.25.2-5.05.23.4-3.7
Bone: elastic displacement0.30.30.7-0.80.6-0.6-0.6-0.60.4-0.2-0.20.5
Bone: elastic work0.81.12.40.2-1.11.21.11.1-1.21.50.5-0.7
Bone: endosteal estimation1.12.55.6-1.41.4-1.4-1.3-1.32.0-1.6-2.40.9
Bone: endosteal perimeter1.63.36.0-1.01.7-1.9-1.7-1.72.4-2.3-2.21.1
Epididymis fat weight0.62.23.9-0.61.1-1.4-1.3-1.32.0-1.5-2.01.7
Delta time in closed arm before/after self-admin0.90.92.6-0.7-0.81.00.80.8-1.11.6-0.7-0.6
Delta time in open arm before/after self-admin2.01.95.02.2-1.41.31.51.5-1.40.71.2-0.7
Diff in mean of infusions in LGA sessions2.12.63.81.4-1.61.71.71.7-2.01.61.2-1.5
Delay discount exponential model param0.10.10.40.50.1-0.2-0.1-0.10.1-0.40.60.0
Extinction: sum of active levers before priming3.63.94.81.9-2.12.12.22.2-2.01.81.6-1.8
Active lever presses in extinction session 62.72.75.62.4-1.71.71.81.8-1.81.11.3-0.8
Bone: final force1.42.23.11.5-1.81.71.61.6-1.41.51.0-1.3
Bone: final moment1.52.43.41.5-1.81.81.71.7-1.41.61.0-1.3
Food consumed during 24 hour testing period0.10.10.50.4-0.0-0.2-0.2-0.20.3-0.20.7-0.1
Glucose2.53.96.2-2.11.9-1.9-1.9-1.92.3-1.7-2.51.4
Heart weight0.50.83.2-1.80.4-0.3-0.5-0.50.90.2-1.70.0
Delay discount hyperbolic model param0.10.10.40.50.0-0.1-0.0-0.0-0.0-0.30.7-0.1
Intermittent access intake day 1-15 change0.81.73.40.01.3-1.6-1.4-1.41.5-1.80.21.2
Intermittent access intake escalation1.02.14.20.11.5-1.8-1.6-1.61.6-2.00.31.2
Intermittent access intake escalation 20.50.61.50.60.7-0.9-0.8-0.80.8-1.20.50.6
Intermitt. access day 1 inactive lever presses0.41.42.2-0.31.3-1.4-1.4-1.41.1-1.5-0.51.3
Intermitt. access day 15 inactive lever presses0.30.72.01.4-0.90.80.80.8-0.50.41.0-0.3
Intermitt. access escalation Index0.50.71.6-1.31.0-0.9-0.9-0.90.9-0.7-0.40.1
Intermittent access day 1 total infusions0.50.91.6-1.30.8-0.7-0.8-0.81.3-0.8-1.10.8
Intermittent access day 15 total infusions2.84.16.7-1.22.1-2.3-2.2-2.22.6-2.6-0.71.7
Intermittent access terminal intake (last 3 days)1.11.42.7-0.41.1-1.3-1.1-1.11.7-1.6-0.51.1
Intermittent access total infusions1.31.52.7-1.01.2-1.2-1.2-1.21.6-1.5-0.91.1
Intermittent access day 1 locomotion0.30.30.8-0.90.4-0.3-0.3-0.30.7-0.4-0.90.5
Intermittent access day 15 total locomotion0.20.41.20.00.6-0.6-0.4-0.40.8-1.1-0.50.8
Intermittent access total locomotion0.50.61.4-0.30.6-0.6-0.5-0.51.2-1.2-0.80.8
Intermittent access standard deviation0.51.01.8-0.31.1-1.2-1.1-1.11.1-1.4-0.21.0
Left kidney weight0.20.93.6-0.40.4-0.6-0.6-0.61.0-0.7-1.91.1
Right kidney weight0.10.41.5-0.10.2-0.4-0.4-0.40.7-0.5-1.21.0
Cocaine induced anxiety0.10.10.70.8-0.10.10.10.1-0.3-0.1-0.00.6
Post-drug Anxiety0.30.30.80.9-0.60.50.60.6-0.60.40.3-0.0
Baseline Anxiety0.40.51.1-0.2-0.60.70.60.6-0.60.90.4-1.1
Tail length0.51.93.70.8-1.31.21.01.0-1.31.61.9-1.8
Length with tail1.67.18.82.1-2.82.72.52.5-2.62.83.0-3.0
Length without tail3.09.611.42.4-3.33.33.23.2-3.23.42.8-3.0
Times rat made contact with spout0.40.51.8-0.0-0.40.40.30.3-0.50.81.4-1.1
Lifetime Intake1.01.32.1-1.31.1-1.1-1.1-1.11.5-1.2-0.70.8
Liver weight, left0.81.41.8-1.11.3-1.3-1.3-1.31.3-1.1-0.60.9
Liver weight, right1.22.15.0-2.21.5-1.5-1.6-1.61.8-0.9-0.90.0
Locomotor activity0.61.03.4-1.91.1-0.9-1.1-1.10.8-0.2-0.6-0.1
Locomotor testing distance0.81.45.3-2.31.2-1.0-1.2-1.21.0-0.2-0.8-0.1
Locomotor testing rearing0.71.33.8-2.01.2-1.1-1.3-1.31.2-0.4-0.90.2
Locomotion in novel chamber2.12.73.4-1.11.7-1.6-1.6-1.61.8-1.8-1.71.7
Locomotion in novel chamber post-restriction1.72.74.3-0.91.8-1.9-1.7-1.71.7-2.1-1.11.5
Fecal boli incidents, locomotor time 10.20.31.10.70.4-0.6-0.4-0.40.5-1.00.10.7
Change in fecal boli incidents, locomotor task1.21.23.7-1.91.2-1.0-1.2-1.21.1-0.5-0.70.2
Time >=10cm from walls, locomotor time 11.92.14.3-0.41.4-1.6-1.5-1.51.7-2.1-0.81.3
Bouts of movement, locomotor time 10.30.41.91.4-0.30.30.20.2-0.9-0.10.30.7
Total resting periods, locomotor time 10.30.41.91.4-0.30.30.30.3-0.8-0.10.30.7
Rest time, locomotor task time 11.11.32.1-0.71.3-1.5-1.2-1.21.4-1.40.00.8
Distance moved, locomotor task time 10.20.30.40.2-0.60.60.60.6-0.50.6-0.0-0.5
Vertical activity count, locomotor time 10.20.60.8-0.90.8-0.7-0.8-0.80.8-0.6-0.70.3
Time >=10cm from walls, locomotor time 20.20.20.90.90.1-0.2-0.1-0.10.2-0.80.40.6
Bouts of movement, locomotor time 20.91.41.71.3-1.31.21.31.3-1.31.11.0-1.0
Total resting periods, locomotor time 20.40.70.90.9-0.90.80.90.9-0.90.70.7-0.7
Rest time, locomotor task time 22.63.34.2-1.72.0-2.0-2.0-2.02.0-1.9-1.01.4
Distance moved, locomotor task time 20.60.71.01.0-0.80.90.90.9-1.00.80.6-0.5
Vertical activity count, locomotor time 20.00.10.2-0.30.10.0-0.1-0.1-0.20.30.2-0.5
Light reinforcement 10.10.31.60.10.1-0.1-0.1-0.10.1-0.11.3-0.9
Light reinforcement 20.20.31.00.90.1-0.5-0.3-0.30.6-1.0-0.10.6
Bone: marrow area1.32.95.9-1.51.5-1.6-1.5-1.52.2-1.7-2.41.0
Bone: maximum diameter0.10.20.91.0-0.50.40.50.5-0.1-0.00.1-0.2
Bone: maximum force1.93.35.22.0-2.32.12.22.2-1.61.80.4-1.0
Bone: maximum moment2.03.55.42.0-2.32.22.22.2-1.71.90.4-1.1
Mean time between licks in bursts0.30.72.5-0.7-0.70.90.60.6-0.61.60.2-0.8
Mean num. licks in bursts0.00.10.2-0.40.3-0.2-0.1-0.1-0.00.0-0.30.2
Cd content in liver0.80.92.1-0.41.1-1.2-0.9-0.91.0-1.4-0.50.3
Co content in liver0.60.71.8-1.41.1-0.9-1.0-1.00.6-0.50.5-0.2
Cu content in liver0.00.00.1-0.20.1-0.1-0.1-0.1-0.1-0.1-0.20.3
Fe content in liver0.00.10.1-0.40.3-0.2-0.1-0.10.2-0.3-0.3-0.1
K content in liver0.50.51.00.4-0.90.80.50.5-0.50.90.7-1.0
Mg content in liver0.20.21.4-0.6-0.10.20.00.00.10.50.2-1.2
Mn content in liver3.23.54.92.2-2.22.02.02.0-1.91.71.5-1.2
Na content in liver0.60.61.30.7-0.80.70.70.7-0.50.71.1-1.1
Rb content in liver2.22.64.3-2.11.7-1.7-2.0-2.01.8-1.2-1.00.4
Se content in liver0.10.20.80.9-0.40.20.30.3-0.1-0.1-0.20.4
Sr content in liver4.23.64.52.0-2.02.02.02.0-2.11.81.6-1.2
Zn content in liver2.22.43.31.3-1.71.71.81.8-1.81.60.9-1.2
Bone: minimum diameter0.61.13.0-0.60.7-0.9-0.9-0.91.5-1.1-1.70.7
Time in familiar zone, hab. session 10.10.10.7-0.0-0.20.40.40.4-0.10.30.1-0.8
Time in novel zone, hab. session 11.11.11.6-1.31.2-1.2-1.3-1.31.1-0.8-0.30.7
Total zone transitions, hab. session 10.40.62.10.4-0.50.40.40.4-0.60.51.3-1.5
Total locomotion distance, hab. session 10.10.10.3-0.20.4-0.4-0.3-0.30.4-0.6-0.3-0.3
Locomotion velocity, hab. session 10.00.10.20.3-0.20.20.20.2-0.3-0.00.1-0.4
Time in familiar zone, hab. session 20.30.30.8-0.60.4-0.2-0.3-0.30.40.10.9-0.8
Time in novel zone, hab. session 20.30.30.60.4-0.60.60.60.6-0.60.5-0.70.3
Total zone transitions, hab. session 21.51.95.30.3-1.31.41.21.2-1.21.61.2-2.3
Total locomotion distance, hab. session 20.20.21.4-0.3-0.30.30.20.2-0.20.50.1-1.2
Locomotion velocity, hab. session 20.10.10.9-0.3-0.10.10.00.00.00.2-0.1-0.9
Novel to familiar place preference ratio1.61.73.11.8-1.61.51.41.4-1.51.10.00.2
Novelty place preference1.01.12.31.5-1.31.11.11.1-1.10.8-0.30.5
Time in novel zone, NPP test1.11.12.01.4-1.31.21.11.1-1.20.9-0.30.5
Total zone transitions, NPP test1.01.43.20.4-1.11.21.11.1-1.31.31.0-1.8
Total locomotion distance, NPP test0.10.10.3-0.5-0.00.1-0.0-0.0-0.20.3-0.4-0.4
Locomotion velocity, NPP test0.00.10.2-0.40.1-0.0-0.1-0.1-0.20.1-0.2-0.4
Intraocular pressure0.10.10.20.30.3-0.3-0.3-0.30.2-0.50.30.2
Delta distance traveled before/after self-admin0.40.41.3-1.10.8-0.6-0.6-0.60.4-0.30.1-0.5
Delta ambulatory time before/after self-admin0.50.61.7-1.31.0-0.8-0.9-0.90.7-0.5-0.1-0.1
Parametrial fat weight1.63.87.4-1.11.7-1.9-1.7-1.72.3-2.2-2.71.7
Pavlov. Cond. lever latency0.81.01.3-0.91.1-1.1-1.1-1.10.9-0.9-0.51.1
Pavlov. Cond. magazine entry latency0.81.02.11.4-1.21.11.31.3-0.80.60.3-0.4
Pavlov. Cond. change in total contacts0.40.41.61.3-0.60.50.70.7-0.4-0.20.1-0.1
Pavlov. Cond. index score0.60.81.61.3-1.00.91.11.1-0.80.50.6-0.5
Pavlov. Cond. latency score0.50.60.90.9-0.90.91.01.0-0.70.60.5-0.7
Pavlov. Cond. lever contacts0.40.50.80.6-0.80.70.80.8-0.50.60.3-0.9
Pavlov. Cond. magazine entry number0.81.02.5-1.61.0-1.0-1.2-1.21.0-0.4-0.70.2
Pavlov. Cond. intertrial magazine entries0.40.42.40.9-0.20.10.10.1-0.4-0.3-0.61.5
Pavlov. Cond. lever-magazine prob. diff.0.70.92.01.4-1.01.01.11.1-0.80.40.6-0.5
Pavlov. Cond. response bias0.81.02.21.5-1.11.01.21.2-0.90.60.7-0.6
Pavlov. Cond. lever latency0.60.81.2-1.01.0-1.0-1.1-1.10.7-0.7-0.80.6
Pavlov. Cond. magazine entry latency4.85.87.52.7-2.72.62.72.7-2.62.21.8-1.2
Pavlov. Cond. change in total contacts1.52.44.52.1-1.61.51.81.8-1.30.91.6-0.9
Pavlov. Cond. index score2.63.55.52.3-2.12.02.22.2-1.81.51.4-0.7
Pavlov. Cond. latency score2.33.15.12.3-2.01.92.12.1-1.71.31.1-0.6
Pavlov. Cond. lever contacts0.50.71.11.1-0.90.91.01.0-0.70.60.8-0.4
Pavlov. Cond. magazine entry number7.28.811.8-3.43.3-3.2-3.4-3.43.2-2.6-2.11.4
Pavlov. Cond. intertrial magazine entries1.21.82.9-1.01.6-1.6-1.5-1.51.5-1.7-0.50.6
Pavlov. Cond. lever-magazine prob. diff.3.14.16.12.5-2.32.12.42.4-2.01.61.5-0.8
Pavlov. Cond. response bias2.12.93.91.8-1.91.82.02.0-1.61.51.4-1.0
Time in closed arm before self-admin0.10.10.40.6-0.0-0.2-0.1-0.10.4-0.50.50.0
Time in closed arm after self-admin0.80.81.6-1.30.8-0.9-1.0-1.01.0-0.5-0.70.7
Time in open arm before self-admin1.21.46.3-2.51.2-0.8-1.1-1.10.8-0.1-0.8-0.1
Time in open arm after self-admin0.30.40.80.3-0.40.70.70.7-0.90.60.4-0.6
Bone: periosteal estimation0.10.10.60.3-0.1-0.00.00.00.6-0.4-0.7-0.0
Bone: periosteal perimeter0.00.10.30.6-0.2-0.00.10.10.4-0.4-0.0-0.2
Bone: post-yield work0.30.52.80.10.2-0.30.00.00.9-0.8-1.70.3
Progressive ratio test 1 active lever presses0.50.60.9-0.60.9-0.8-0.8-0.80.8-1.0-0.60.8
Progressive ratio test 1 breakpoint0.50.61.0-0.60.8-0.8-0.8-0.80.8-1.0-0.60.8
Progressive ratio test 1 inactive lever presses0.30.40.60.7-0.80.80.70.7-0.70.70.4-0.4
Progressive ratio test 2 active lever presses0.91.12.3-0.31.1-1.1-1.0-1.01.3-1.5-0.61.0
Progressive ratio test 2 breakpoint0.91.02.2-0.31.0-1.1-0.9-0.91.2-1.5-0.51.0
Progressive ratio test 2 inactive lever presses0.50.91.6-0.10.8-0.9-0.8-0.81.1-1.3-0.81.2
Incentive Sensitization - Responses0.30.51.11.1-0.80.70.90.9-0.40.40.1-0.2
Incentive Sensitization - Breakpoint0.30.30.91.0-0.60.60.80.8-0.30.20.1-0.1
Sum of active levers in priming session hrs 5-61.71.66.82.6-1.00.81.11.1-1.10.01.5-0.1
Progressive ratio0.10.10.50.1-0.10.00.00.00.4-0.20.5-0.7
Food seeking constrained by brief footshock0.10.20.6-0.50.2-0.2-0.3-0.30.2-0.00.4-0.8
Seeking ratio, punishment vs. effort0.10.21.0-1.00.3-0.1-0.2-0.2-0.10.4-0.50.0
Retroperitoneal fat weight3.816.120.0-3.94.0-4.1-4.2-4.24.5-3.7-4.43.1
Reaction time number correct0.61.11.80.6-1.11.10.90.9-0.81.31.3-1.3
Reaction time mean minus median0.41.04.62.2-0.80.60.90.9-0.9-0.20.20.8
Reaction time mean minus median AUC0.20.42.21.5-0.40.30.50.5-0.6-0.10.50.5
Reaction time num false alarms0.30.52.5-1.60.8-0.5-0.5-0.50.30.0-0.5-0.0
Reaction time num false alarms AUC0.10.21.3-1.10.30.10.10.1-0.30.6-0.2-0.3
Reaction time trials correct on left0.61.11.80.6-1.11.10.90.9-0.81.31.3-1.3
Reaction time trials on left0.61.21.90.6-1.11.10.90.9-0.81.31.4-1.3
Reaction time mean0.10.20.80.80.3-0.40.10.10.0-0.9-0.10.7
Reaction time mean AUC0.20.20.90.70.3-0.4-0.1-0.10.2-0.90.10.7
Median of all reaction times0.10.10.50.40.3-0.30.10.10.1-0.7-0.10.3
Reaction time omissions0.30.51.31.1-0.60.50.80.8-0.90.30.6-0.2
Reaction time false alarm rate0.40.62.1-1.40.9-0.6-0.5-0.50.3-0.3-1.00.5
Reaction time premature initiation rate4.25.810.01.0-2.62.72.52.5-2.33.21.8-2.4
Reaction time premature initiations4.78.313.61.4-3.13.22.92.9-2.83.72.6-3.0
Std. dev. reaction times0.20.41.21.10.3-0.30.10.1-0.1-0.9-0.11.1
Reaction time trials completed0.61.21.90.6-1.11.10.90.9-0.81.31.4-1.3
Reaction time trials AUC0.51.01.70.4-1.01.00.80.8-0.71.31.3-1.3
Run reversals in cocaine runway, females0.50.51.2-1.0-0.50.70.50.5-0.31.0-0.2-1.1
Run reversals in cocaine runway, males0.40.40.6-0.60.7-0.7-0.8-0.80.6-0.60.10.4
Latency to leave start box in cocaine runway0.50.51.3-0.80.6-0.7-0.6-0.60.9-0.6-1.10.5
Latency to leave start box in cocaine runway, F0.00.00.10.1-0.20.20.20.2-0.00.3-0.20.1
Latency to leave start box in cocaine runway, M2.32.12.8-1.41.5-1.5-1.5-1.51.7-1.4-1.60.8
Std. dev. time between licks in bursts0.20.21.4-1.20.2-0.1-0.3-0.30.20.6-0.3-0.3
Total sessions with >9 infusions0.81.01.4-1.21.1-1.1-1.0-1.01.1-1.1-0.50.7
Short access day 1 total inactive lever presses0.20.20.7-0.80.4-0.2-0.1-0.10.4-0.3-0.80.4
Short access day 10 total inactive lever presses0.20.60.8-0.80.9-0.8-0.8-0.80.7-0.7-0.50.5
Short access day 1 total infusions1.21.62.7-1.61.4-1.3-1.3-1.31.5-1.2-0.50.8
Short access day 10 total infusions0.40.51.0-1.00.6-0.6-0.6-0.61.0-0.6-0.40.3
Short access total infusions0.81.02.8-1.71.0-0.9-1.0-1.01.2-0.8-0.60.5
Short access day 1 locomotion0.30.30.6-0.60.6-0.6-0.6-0.60.8-0.7-0.00.3
Short access day 10 total locomotion0.00.00.1-0.1-0.00.00.10.10.3-0.20.1-0.1
Short access total locomotion0.20.20.4-0.50.5-0.4-0.4-0.40.7-0.7-0.30.3
One hour access (0.3 mA shock)1.11.32.2-0.91.2-1.2-1.1-1.11.5-1.4-0.51.0
Compulsive drug intake0.91.02.10.3-1.01.11.11.1-1.21.50.4-0.9
One hour access (shock baseline)2.74.16.6-1.12.1-2.3-2.2-2.22.4-2.6-0.91.8
Social response proportion0.10.10.40.1-0.50.30.10.1-0.20.60.30.1
Social responses0.30.31.50.3-0.40.30.20.2-0.40.61.2-0.7
Social time0.10.10.6-0.1-0.0-0.0-0.1-0.1-0.20.30.8-0.7
Soleus weight2.67.710.0-2.83.1-3.1-3.2-3.23.1-2.8-1.71.3
Bone: stiffness0.61.02.71.6-1.21.01.01.0-0.70.60.8-0.6
Tibialis anterior weight8.328.034.55.3-5.95.85.85.8-5.95.24.1-3.5
Time to tail flick, vehicle, before self-admin0.10.10.30.2-0.30.20.40.4-0.10.1-0.60.3
Time to tail flick, vehicle, after self-admin0.20.30.9-0.3-0.50.60.50.5-0.40.70.4-0.9
Time to tail flick, test, before self-admin0.30.30.6-0.8-0.30.60.50.5-0.10.7-0.6-0.6
Time to tail flick, test, after self-admin0.10.10.40.7-0.30.10.20.2-0.1-0.10.00.4
Delta time to tail flick, vehicle, before/after SA0.30.30.8-0.1-0.50.60.30.3-0.50.70.6-0.9
Delta time to tail flick, test, before/after SA0.40.42.21.5-0.2-0.10.10.1-0.4-0.40.60.7
Tibia length1.43.89.53.1-2.21.82.02.0-1.91.11.8-1.1
Ambulatory time before self-admin1.52.24.82.2-1.61.51.61.6-1.40.91.2-0.9
Ambulatory time after self-admin0.30.30.80.9-0.40.40.50.5-0.40.10.9-0.7
Bone: tissue strength0.20.20.4-0.50.3-0.3-0.6-0.60.6-0.00.5-0.5
Total heroin consumption5.56.49.22.9-2.72.62.72.7-3.02.41.7-1.6
Bone: trabecular number0.71.21.90.9-1.31.41.41.4-1.01.10.2-0.8
Bone: trabecular spacing0.40.50.9-1.00.8-0.7-0.9-0.90.6-0.30.30.2
Bone: trabecular thickness0.10.20.60.10.4-0.4-0.3-0.30.5-0.8-0.30.3
Bone: trabecular tissue density4.26.29.2-2.33.0-2.9-2.9-2.92.6-2.8-0.81.1
Water consumed over 24 hours1.01.33.10.7-1.11.00.90.9-0.91.31.8-1.4
Number of responses in last shaping day0.10.10.3-0.3-0.30.40.30.3-0.50.6-0.40.0