Hub : Genes

Znrd2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA intron excision ratio chr1_212447710_212448242 0.35 0.11 0.0e+00 0.4 0.41 0.4 0.41 8.7e-34 2.7e-35 5.9e-34 5.9e-35
2 Brain intron excision ratio chr1_212447710_212448005 0.22 0.09 0.0e+00 0.29 0.27 0.28 0.28 7.1e-27 3.6e-25 3.2e-26 4.2e-26
3 IC intron excision ratio chr1_212447710_212448242 0.27 0.11 8.0e-11 0.16 0.16 0.15 0.12 3.0e-07 3.5e-07 6.0e-07 1.3e-05
4 pVTA gene expression Znrd2 0.1 0.05 1.3e-09 0.12 0.12 0.11 0.12 7.3e-10 1.4e-09 5.6e-09 1.0e-09
5 Brain intron excision ratio chr1_212447710_212448242 0.33 0.1 0.0e+00 0.42 0.42 0.42 0.43 1.0e-42 3.5e-42 1.6e-42 1.3e-43
6 IC gene expression Znrd2 0.42 0.14 2.2e-16 0.27 0.26 0.25 0.26 1.2e-11 1.6e-11 9.9e-11 3.2e-11
7 BLA gene expression Znrd2 0.22 0.1 6.0e-13 0.23 0.23 0.23 0.22 1.8e-12 2.3e-12 2.7e-12 6.5e-12
8 PL alternative polyA NM_001109537.2 0.04 0.03 6.6e-05 0.04 0.04 0.03 0.04 3.9e-05 6.0e-05 4.0e-04 5.0e-05
9 PL alternative polyA XM_063274608.1 0.04 0.03 1.0e-04 0.04 0.03 0.03 0.03 8.7e-05 1.1e-04 6.7e-04 1.7e-04
10 PL gene expression Znrd2 0.24 0.09 0.0e+00 0.34 0.34 0.34 0.34 5.1e-39 9.6e-38 1.5e-38 8.5e-39
11 OFC intron excision ratio chr1_212447710_212448242 0.22 0.12 1.0e-03 0.08 0.13 0.1 0.1 6.3e-03 5.5e-04 2.0e-03 2.5e-03
12 NAcc gene expression Znrd2 0.17 0.07 0.0e+00 0.22 0.21 0.22 0.21 1.3e-32 4.0e-31 6.7e-32 1.1e-31
13 Adipose intron excision ratio chr1_212447710_212448242 0.05 0.03 2.8e-04 0.01 0.01 0.01 0.01 3.9e-02 7.6e-03 1.5e-02 4.5e-02
14 Brain gene expression Znrd2 0.25 0.1 0.0e+00 0.25 0.25 0.25 0.26 3.7e-23 1.9e-23 4.0e-23 6.8e-24
15 IL gene expression Znrd2 0.6 0.18 7.9e-07 0.12 0.18 0.2 0.18 7.4e-04 4.0e-05 1.3e-05 3.2e-05
16 LHb gene expression Znrd2 0.21 0.11 9.5e-05 0.11 0.22 0.15 0.16 1.3e-03 6.8e-06 2.2e-04 1.3e-04
17 OFC gene expression Znrd2 0.25 0.13 1.1e-04 0.18 0.12 0.19 0.18 4.0e-05 9.4e-04 2.9e-05 5.1e-05
18 pVTA mRNA stability Znrd2 0.04 0.03 9.8e-04 0.05 0.04 0.04 0.04 1.1e-04 4.3e-04 5.3e-04 6.3e-04
19 Brain mRNA stability Znrd2 0.04 0.03 2.0e-03 0.04 0.03 0.04 0.03 2.3e-04 1.5e-03 2.8e-04 4.3e-04
20 Adipose isoform ratio NM_001109537.2 0.08 0.05 4.1e-03 0.02 0 0.01 0.01 2.4e-03 3.6e-01 2.7e-02 3.4e-02
21 Liver gene expression Znrd2 0.04 0.03 9.5e-04 0.01 0.01 0.01 0.01 7.0e-03 1.4e-02 6.6e-02 1.7e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density0.50.93.41.20.8-1.01.00.90.90.80.8-0.80.81.51.01.6-0.20.00.00.9-0.1-0.7-0.6-1.8
Area under the delay curve0.20.31.40.1-0.20.2-0.2-0.2-0.0-0.4-0.40.4-0.40.5-0.30.30.7-0.80.6-0.5-0.2-1.2-1.0-1.1
BMI with tail2.06.923.23.32.6-2.82.82.52.42.42.4-2.42.43.72.54.3-1.31.1-0.42.1-1.7-1.5-1.4-4.8
BMI without tail0.52.810.32.11.5-1.91.91.61.51.51.5-1.51.52.61.62.7-0.60.3-0.41.0-0.9-1.1-1.1-3.2
Body weight2.711.819.84.13.7-3.93.93.73.73.83.8-3.83.84.13.64.4-3.03.2-2.63.80.71.11.1-3.1
Weight adjusted by age0.72.03.81.41.4-1.61.61.51.51.31.3-1.31.31.11.41.1-1.62.0-1.51.81.01.41.60.0
Bone surface4.07.811.73.33.0-3.23.23.13.13.13.1-3.13.13.23.13.4-2.32.3-1.93.41.41.31.4-2.0
Bone volume1.32.65.22.11.6-1.91.91.81.81.71.7-1.71.72.01.82.3-1.11.1-0.72.00.50.30.4-1.8
Breakpoint value in progressive ratio session2.13.85.22.22.2-2.32.32.22.02.12.1-2.12.12.02.22.0-2.12.0-1.61.91.51.31.5-1.0
Number of licking bursts0.10.40.80.70.6-0.90.90.70.60.80.8-0.80.80.60.80.6-0.70.8-0.50.60.20.50.5-0.3
Context. condit. distance diff. score2.12.53.3-1.6-1.71.8-1.8-1.8-1.6-1.7-1.71.7-1.7-1.4-1.8-1.31.7-1.71.6-1.5-1.2-1.5-1.40.1
Locomotion velocity, session 10.00.00.1-0.1-0.10.0-0.0-0.10.1-0.1-0.10.1-0.1-0.1-0.0-0.1-0.10.3-0.40.20.30.20.20.3
Locomotion distance, session 10.60.73.11.00.7-0.80.80.70.80.70.7-0.70.71.30.81.4-0.20.2-0.20.6-0.8-0.6-0.6-1.8
Locomotion velocity, session 22.53.05.02.11.9-1.91.91.91.91.81.8-1.81.82.12.02.2-1.61.7-1.41.90.30.50.5-1.6
Locomotion distance, session 20.71.02.91.21.0-1.11.11.01.00.90.9-0.90.91.61.01.5-0.50.5-0.50.7-0.7-0.3-0.3-1.7
Locomotion velocity, session 30.30.41.5-0.2-0.20.4-0.4-0.3-0.4-0.5-0.50.5-0.5-0.0-0.30.40.5-0.20.7-0.2-1.2-1.2-1.1-1.2
Locomotion distance, session 30.00.00.0-0.10.00.1-0.1-0.1-0.2-0.2-0.20.2-0.2-0.1-0.1-0.10.10.10.1-0.1-0.0-0.2-0.1-0.2
Stereotopy head waving bouts, day 30.91.14.1-0.6-0.91.1-1.1-1.0-0.9-0.8-0.80.8-0.8-0.4-1.1-0.01.2-0.81.1-0.6-2.0-1.5-1.5-1.0
Stereotopy head waving duration, day 30.91.12.1-0.8-1.11.3-1.3-1.2-0.9-0.9-0.90.9-0.9-0.6-1.3-0.41.3-1.11.2-0.7-1.4-1.2-1.3-0.4
Locomotion velocity, session 70.91.03.8-0.2-0.70.5-0.5-0.5-0.6-0.7-0.70.7-0.70.1-0.50.40.9-1.11.3-1.0-2.0-1.8-1.8-1.7
Locomotion distance, session 70.20.31.70.1-0.1-0.00.00.0-0.20.00.0-0.00.00.5-0.10.50.3-0.40.3-0.6-1.2-0.9-1.0-1.3
Stereotopy head waving bouts, day 70.10.10.40.0-0.20.3-0.3-0.2-0.1-0.2-0.20.2-0.20.0-0.10.20.4-0.40.6-0.0-0.4-0.5-0.5-0.5
Stereotopy head waving duration, day 70.50.61.21.10.8-0.70.70.81.00.70.7-0.70.71.10.91.1-0.50.4-0.20.80.3-0.00.0-1.0
Locomotion velocity, session 80.91.12.00.91.2-1.11.11.11.01.11.1-1.11.10.91.10.8-1.11.3-1.41.20.71.11.10.0
Locomotion distance, session 80.40.62.4-0.4-0.60.6-0.6-0.7-0.5-0.6-0.60.6-0.6-0.2-0.70.10.8-0.60.9-0.2-1.5-1.2-1.2-1.0
Degree of sensitization distance0.20.31.80.3-0.1-0.10.10.00.00.20.2-0.20.20.5-0.00.70.3-0.30.3-0.1-1.3-0.7-0.8-1.1
Degree of sensitization stereotypy0.30.40.70.80.7-0.60.60.70.70.60.6-0.60.60.70.80.8-0.60.5-0.10.70.50.20.2-0.6
Conditioned locomotion1.51.82.81.41.4-1.41.41.41.41.41.4-1.41.41.31.41.3-1.41.6-1.41.71.01.11.1-0.3
Cocaine response after cond. corrected1.11.62.4-1.3-1.61.4-1.4-1.4-1.4-1.4-1.41.4-1.4-1.2-1.3-1.11.3-1.11.0-1.3-1.2-1.2-1.20.3
Cocaine response after cond. not corrected0.81.11.7-1.1-1.31.1-1.1-1.2-1.2-1.2-1.21.2-1.2-1.0-1.1-0.91.1-0.80.9-1.1-1.1-1.0-0.90.2
Cocaine response before conditioning0.80.91.41.01.1-1.21.21.11.01.01.0-1.01.00.81.00.8-1.11.0-0.70.80.60.90.9-0.3
Saline control response3.85.26.62.52.6-2.52.52.52.52.52.5-2.52.52.42.62.3-2.22.2-2.42.21.21.81.8-0.8
Bone: connectivity density2.23.56.72.32.0-2.22.22.12.02.02.0-2.02.02.52.12.6-1.31.1-1.12.00.60.30.5-2.0
Bone: cortical apparent density0.10.20.90.20.3-0.30.30.30.30.40.4-0.40.40.20.4-0.1-0.50.2-0.4-0.31.00.50.50.2
Bone: cortical area0.81.32.21.11.1-1.41.41.21.11.11.1-1.11.10.81.31.0-1.31.5-1.01.40.91.01.0-0.1
Bone: cortical porosity0.20.20.60.60.4-0.40.40.30.50.40.4-0.40.40.70.30.7-0.00.2-0.10.50.2-0.1-0.3-0.8
Bone: cortical porosity0.50.61.21.00.7-0.70.70.70.90.80.8-0.80.81.10.71.1-0.40.6-0.50.90.30.10.0-0.9
Bone: cortical thickness3.25.37.82.02.3-2.62.62.52.32.32.3-2.32.31.72.61.4-2.82.8-2.71.82.72.42.40.4
Bone: cortical thickness0.60.81.70.60.9-1.01.00.90.70.80.8-0.80.80.51.00.3-1.11.1-1.30.41.31.01.00.5
Bone: cortical tissue density0.20.31.20.30.4-0.40.40.50.50.60.6-0.60.60.30.5-0.0-0.70.3-0.6-0.11.10.70.70.2
Condit. Reinf. active minus inactive responses0.10.20.50.50.4-0.30.30.40.40.40.4-0.40.40.70.50.6-0.2-0.0-0.1-0.0-0.4-0.2-0.2-0.7
Condit. Reinf. active-inactive response ratio0.00.00.20.1-0.00.1-0.10.00.10.00.0-0.00.00.20.10.00.0-0.40.0-0.50.4-0.1-0.2-0.2
Condit. Reinf. active responses0.10.20.90.30.1-0.20.20.20.10.10.1-0.10.10.40.40.5-0.1-0.10.30.0-1.0-0.5-0.5-0.9
Condit. Reinf. inactive responses0.20.32.5-0.0-0.20.1-0.1-0.1-0.3-0.2-0.20.2-0.2-0.1-0.00.40.2-0.10.60.2-1.6-0.8-0.6-0.8
Incentive salience index mean0.30.41.70.80.6-0.60.60.60.50.60.6-0.60.61.00.71.1-0.30.1-0.10.4-0.7-0.4-0.5-1.3
Condit. Reinf. lever presses0.50.71.51.00.9-0.90.90.80.70.90.9-0.90.90.90.91.2-0.80.7-0.31.1-0.40.00.0-1.0
Condit. Reinf. active minus inactive responses0.00.00.2-0.1-0.10.1-0.1-0.1-0.2-0.2-0.20.2-0.2-0.2-0.1-0.10.3-0.40.4-0.0-0.2-0.1-0.0-0.1
Condit. Reinf. active-inactive response ratio0.40.61.4-0.7-0.80.7-0.7-0.8-0.8-0.8-0.80.8-0.8-0.9-0.7-0.50.8-0.61.2-0.3-1.0-0.7-0.6-0.0
Condit. Reinf. active responses0.10.20.40.50.5-0.50.50.50.40.40.4-0.40.40.60.50.5-0.1-0.20.00.20.1-0.00.0-0.6
Condit. Reinf. inactive responses0.40.61.70.90.9-0.90.90.90.80.90.9-0.90.91.30.80.9-0.50.1-0.60.20.40.10.1-0.9
Condit. Reinf. lever presses1.92.84.01.91.9-1.91.91.91.71.81.8-1.81.81.62.01.7-1.61.6-1.21.91.11.21.2-0.7
Condit. Reinf. lever reinforcers received0.30.40.70.80.8-0.80.80.80.70.80.8-0.80.80.90.80.7-0.50.1-0.30.50.40.40.4-0.5
Conditioned reinforcement - actives0.00.21.0-0.1-0.0-0.20.20.00.00.10.1-0.10.1-0.60.1-0.3-0.20.7-0.10.60.10.90.81.0
Conditioned reinforcement - inactives1.23.35.8-2.1-2.01.9-1.9-1.9-2.1-2.0-2.02.0-2.0-2.4-1.8-2.21.7-1.81.9-1.6-0.7-0.8-0.61.6
Conditioned locomotion6.29.313.3-3.5-3.33.3-3.3-3.3-3.3-3.3-3.33.3-3.3-3.6-3.3-3.52.9-3.02.9-3.3-1.6-1.6-1.62.2
Patch foraging indifference point 0 sec0.00.00.2-0.10.20.1-0.1-0.0-0.30.00.0-0.00.00.0-0.30.00.1-0.40.3-0.4-0.2-0.1-0.2-0.2
Patch foraging indifference point AUC1.53.54.61.82.0-1.91.91.92.02.12.1-2.12.11.52.01.4-2.01.8-1.71.72.11.91.8-0.1
Delay disc. indifference point, 0s delay0.91.03.1-0.4-1.00.8-0.8-1.0-0.4-0.7-0.70.7-0.70.1-1.00.11.4-1.31.0-0.8-0.9-1.7-1.7-1.4
Delay disc. indifference point, 16s delay0.60.81.8-0.7-0.80.8-0.8-0.7-1.0-1.0-1.01.0-1.0-0.5-0.8-0.60.9-1.31.2-1.1-0.7-1.3-0.9-0.7
Delay disc. indifference point, 2s delay0.20.20.6-0.2-0.40.4-0.4-0.4-0.3-0.5-0.50.5-0.5-0.2-0.1-0.00.6-0.40.6-0.5-0.8-0.7-0.7-0.4
Delay disc. indifference point, 24s delay0.10.10.2-0.3-0.30.3-0.3-0.3-0.1-0.5-0.50.5-0.5-0.1-0.5-0.30.2-0.1-0.1-0.20.2-0.30.10.1
Delay disc. indifference point, 4s delay0.30.31.3-0.2-0.30.4-0.4-0.4-0.2-0.4-0.40.4-0.40.3-0.40.20.8-0.80.5-0.8-0.7-1.1-1.0-0.8
Delay disc. indifference point, 8s delay0.10.20.7-0.0-0.20.2-0.2-0.30.0-0.3-0.30.3-0.30.4-0.50.20.6-0.70.3-0.20.1-0.8-0.8-0.6
Indifference point function ln k3.711.314.4-3.6-3.63.6-3.6-3.6-3.8-3.8-3.83.8-3.8-3.2-3.7-3.03.4-3.13.0-3.3-3.3-2.9-2.80.9
Indifference point function log k3.711.314.4-3.6-3.63.6-3.6-3.6-3.8-3.8-3.83.8-3.8-3.2-3.7-3.03.4-3.13.0-3.3-3.3-2.9-2.80.9
Patch foraging total patch changes 0 sec0.00.00.1-0.10.20.0-0.00.1-0.10.10.1-0.10.1-0.0-0.2-0.1-0.1-0.1-0.1-0.20.10.20.20.2
Patch foraging total patch changes 12 sec4.66.18.62.72.9-2.82.82.82.62.82.8-2.82.82.72.72.5-2.52.0-2.12.11.81.61.5-1.4
Patch foraging total patch changes 18 sec0.30.81.21.01.0-1.01.01.01.01.11.1-1.11.11.01.01.0-0.90.7-0.50.80.50.50.4-0.7
Patch foraging total patch changes 24 sec0.93.04.01.61.9-1.71.71.81.82.02.0-2.02.01.41.61.3-1.91.7-1.91.51.62.01.80.2
Patch foraging total patch changes 6 sec1.01.72.71.41.7-1.51.51.61.21.51.5-1.51.51.41.51.4-1.40.9-1.10.80.60.80.8-0.9
Patch foraging time to switch 0 sec0.72.56.22.11.7-1.71.71.71.71.61.6-1.61.62.21.62.5-1.00.9-0.41.6-0.2-0.4-0.3-2.5
Patch foraging water rate 0 sec1.65.911.5-3.1-2.72.7-2.7-2.7-2.7-2.5-2.52.5-2.5-3.3-2.7-3.42.0-1.71.4-2.0-0.5-0.2-0.42.9
Patch foraging water rate 12 sec3.112.519.8-4.4-3.93.9-3.9-4.0-3.7-4.0-4.04.0-4.0-4.3-3.9-4.53.3-2.82.2-3.3-1.5-1.3-1.33.4
Patch foraging water rate 18 sec1.84.05.7-2.4-2.42.3-2.3-2.2-2.2-2.2-2.22.2-2.2-2.3-2.1-2.31.9-1.51.3-1.8-1.3-1.0-1.21.5
Patch foraging water rate 24 sec4.15.89.1-2.9-2.82.8-2.8-2.8-2.5-2.7-2.72.7-2.7-3.0-2.7-3.02.2-1.71.5-1.8-1.3-0.8-0.82.2
Patch foraging water rate 6 sec3.75.59.1-3.0-2.72.6-2.6-2.6-2.6-2.6-2.62.6-2.6-3.0-2.5-3.02.1-1.61.3-2.2-1.2-0.7-0.72.4
Seeking ratio, delayed vs. immediate footshock0.20.30.9-0.1-0.10.3-0.3-0.2-0.5-0.4-0.40.4-0.40.2-0.30.10.5-0.80.8-0.8-0.9-0.9-0.9-1.0
Distance traveled before self-admin0.30.71.21.10.9-0.90.90.80.91.01.0-1.01.01.00.91.1-0.60.5-0.31.00.40.10.3-0.9
Distance traveled after self-admin0.20.31.70.60.6-0.70.70.50.50.50.5-0.50.50.50.50.4-0.6-0.0-0.40.21.30.50.6-0.1
Extensor digitorum longus weight7.329.036.96.16.0-5.95.95.95.95.85.8-5.85.85.75.95.8-5.55.6-5.05.73.33.33.4-2.7
Bone: elastic displacement0.70.92.8-1.3-0.80.9-0.9-0.9-1.0-1.0-1.01.0-1.0-1.4-0.9-1.50.5-0.3-0.0-0.80.20.30.31.7
Bone: elastic work1.01.32.50.91.2-1.31.31.21.01.11.1-1.11.10.81.20.7-1.31.4-1.61.11.31.21.20.2
Bone: endosteal estimation0.81.96.3-0.8-1.21.2-1.2-1.3-1.3-1.2-1.21.2-1.2-0.7-1.4-0.01.8-1.41.9-0.2-2.5-2.0-1.8-1.3
Bone: endosteal perimeter0.92.35.8-1.0-1.61.3-1.3-1.4-1.5-1.4-1.41.4-1.4-0.9-1.5-0.32.0-1.62.2-0.4-2.4-2.0-1.9-1.0
Epididymis fat weight2.010.313.6-3.4-3.53.6-3.6-3.6-3.3-3.6-3.63.6-3.6-3.6-3.7-3.13.3-2.83.3-2.0-2.8-2.3-2.21.4
Delta time in closed arm before/after self-admin0.10.10.50.30.3-0.30.30.30.30.30.3-0.30.30.50.40.4-0.30.5-0.70.40.10.10.1-0.3
Delta time in open arm before/after self-admin0.20.31.10.40.5-0.50.50.50.40.50.5-0.50.50.10.30.1-0.50.3-0.20.61.00.60.70.3
Diff in mean of infusions in LGA sessions0.40.71.50.80.9-0.90.90.90.80.70.7-0.70.70.71.20.6-1.00.9-1.00.80.60.91.00.1
Delay discount exponential model param0.10.21.0-0.10.1-0.10.10.1-0.10.30.3-0.30.3-0.50.2-0.3-0.50.6-0.40.40.11.00.71.0
Extinction: sum of active levers before priming1.72.64.42.01.8-2.02.01.81.61.71.7-1.71.72.12.02.1-1.51.3-1.11.10.40.50.5-1.7
Active lever presses in extinction session 63.23.35.71.91.8-2.02.01.82.01.91.9-1.91.91.41.91.7-2.02.4-1.72.20.91.71.7-0.3
Bone: final force2.44.06.12.22.2-2.22.22.22.12.22.2-2.22.22.02.12.2-1.92.0-1.72.51.11.31.4-0.9
Bone: final moment2.33.75.82.12.1-2.12.12.12.02.12.1-2.12.11.92.12.1-1.82.0-1.62.41.11.21.3-0.9
Food consumed during 24 hour testing period0.10.31.6-0.00.1-0.10.10.10.30.20.2-0.20.2-0.30.2-0.4-0.40.6-0.50.31.30.91.01.2
Glucose2.84.48.0-1.7-2.12.0-2.0-2.1-2.0-2.0-2.02.0-2.0-1.2-2.1-0.92.6-2.42.5-1.7-2.5-2.8-2.8-1.2
Heart weight1.72.77.5-0.9-1.31.4-1.4-1.4-1.2-1.4-1.41.4-1.4-0.3-1.40.12.1-1.91.8-1.2-2.6-2.7-2.7-1.9
Delay discount hyperbolic model param0.20.21.0-0.10.1-0.20.20.2-0.00.30.3-0.30.3-0.40.2-0.3-0.60.6-0.40.40.21.00.80.9
Intermittent access intake day 1-15 change0.31.53.3-1.5-1.41.4-1.4-1.4-1.3-1.2-1.21.2-1.2-1.8-1.3-1.71.0-1.01.1-1.2-0.4-0.2-0.21.4
Intermittent access intake escalation0.21.23.0-1.4-1.21.2-1.2-1.2-1.2-1.1-1.11.1-1.1-1.7-1.2-1.60.8-0.80.9-1.0-0.20.00.01.5
Intermittent access intake escalation 20.71.12.6-1.3-1.11.2-1.2-1.2-1.1-1.0-1.01.0-1.0-1.6-1.2-1.50.8-0.80.9-1.0-0.00.0-0.01.3
Intermitt. access day 1 inactive lever presses0.00.20.8-0.4-0.40.5-0.5-0.4-0.4-0.5-0.50.5-0.5-0.4-0.5-0.60.3-0.60.4-0.90.4-0.3-0.10.3
Intermitt. access day 15 inactive lever presses0.42.13.1-1.5-1.51.5-1.5-1.4-1.7-1.6-1.61.6-1.6-1.7-1.2-1.41.4-1.51.8-1.2-1.0-1.3-1.10.6
Intermitt. access escalation Index1.33.96.6-2.0-2.22.0-2.0-2.1-2.1-2.0-2.02.0-2.0-1.6-2.0-1.72.4-2.62.1-2.1-1.7-1.9-2.10.2
Intermittent access day 1 total infusions1.44.18.5-1.5-2.01.7-1.7-1.8-1.9-1.8-1.81.8-1.8-1.3-1.7-0.82.6-2.52.7-1.4-2.9-2.8-2.9-0.8
Intermittent access day 15 total infusions2.66.58.7-2.7-2.82.5-2.5-2.6-2.8-2.7-2.72.7-2.7-2.9-2.4-2.52.7-2.62.9-2.3-2.4-2.0-2.01.1
Intermittent access terminal intake (last 3 days)3.15.48.3-2.4-2.62.3-2.3-2.4-2.5-2.4-2.42.4-2.4-2.6-2.2-2.02.6-2.42.9-1.8-2.6-2.1-2.10.7
Intermittent access total infusions3.64.37.8-1.9-2.31.8-1.8-1.9-2.2-2.1-2.12.1-2.1-2.0-1.7-1.42.5-2.32.7-1.6-2.8-2.3-2.30.1
Intermittent access day 1 locomotion1.62.95.3-1.4-1.81.5-1.5-1.6-1.6-1.6-1.61.6-1.6-1.2-1.5-0.92.1-2.12.2-1.5-2.3-2.2-2.3-0.5
Intermittent access day 15 total locomotion1.35.28.1-2.3-2.52.3-2.3-2.3-2.5-2.4-2.42.4-2.4-2.6-2.1-2.12.4-2.52.8-2.1-2.0-2.0-1.90.8
Intermittent access total locomotion6.57.813.2-2.7-3.02.8-2.8-2.8-2.9-2.9-2.92.9-2.9-2.8-2.6-2.13.1-3.23.6-2.4-3.1-2.9-2.90.3
Intermittent access standard deviation0.31.73.3-1.6-1.61.5-1.5-1.5-1.4-1.3-1.31.3-1.3-1.8-1.3-1.71.2-1.21.1-1.3-0.2-0.4-0.51.3
Left kidney weight0.43.34.6-1.6-1.92.1-2.1-2.0-1.6-1.8-1.81.8-1.8-1.5-2.1-1.22.0-2.12.1-1.3-1.7-2.0-2.1-0.1
Right kidney weight0.21.32.1-1.3-1.31.4-1.4-1.4-1.1-1.2-1.21.2-1.2-1.5-1.4-1.21.1-0.81.1-0.7-0.6-0.8-0.80.7
Cocaine induced anxiety0.00.00.10.20.2-0.40.40.20.10.00.0-0.00.00.10.10.1-0.20.1-0.00.10.20.20.1-0.0
Post-drug Anxiety0.80.91.51.01.2-1.21.21.10.90.90.9-0.90.90.80.80.9-1.11.1-0.80.90.40.81.0-0.3
Baseline Anxiety0.30.51.00.60.9-0.60.60.70.70.80.8-0.80.80.60.60.5-0.81.0-0.90.60.40.70.90.0
Tail length0.31.83.61.01.0-1.21.21.21.41.41.4-1.41.41.01.20.6-1.31.3-1.91.21.81.81.50.6
Length with tail1.98.411.32.82.9-3.03.03.03.03.13.1-3.13.12.52.92.3-3.03.3-3.43.22.62.92.7-0.1
Length without tail1.36.911.52.42.7-2.72.72.72.72.62.6-2.62.62.22.62.0-2.93.4-3.13.12.32.62.70.1
Times rat made contact with spout0.40.41.10.80.6-0.70.70.70.70.60.6-0.60.61.00.80.7-0.40.1-0.60.40.90.10.2-0.7
Lifetime Intake2.63.26.5-1.6-1.91.5-1.5-1.6-1.8-1.8-1.81.8-1.8-1.6-1.4-1.12.2-2.02.3-1.4-2.6-2.1-2.1-0.1
Liver weight, left0.71.32.0-1.3-1.41.3-1.3-1.4-1.2-1.3-1.31.3-1.3-1.3-1.3-1.11.2-0.70.8-0.8-0.8-0.7-0.70.7
Liver weight, right2.13.64.7-2.2-2.12.1-2.1-2.1-2.1-2.1-2.12.1-2.1-1.9-2.2-1.82.0-1.41.5-1.6-1.8-1.5-1.50.8
Locomotor activity1.72.64.6-2.1-1.81.7-1.7-1.8-1.9-1.9-1.91.9-1.9-2.1-1.6-2.11.3-1.00.8-1.5-0.4-0.6-0.51.7
Locomotor testing distance1.43.45.8-2.4-2.12.0-2.0-2.0-2.1-2.2-2.22.2-2.2-2.3-1.8-2.41.6-1.30.9-1.7-0.5-0.7-0.51.8
Locomotor testing rearing0.93.45.0-2.2-2.12.0-2.0-2.0-2.0-2.2-2.22.2-2.2-1.9-1.7-2.22.0-1.81.2-1.7-0.2-1.0-0.91.5
Locomotion in novel chamber4.86.47.9-2.8-2.82.8-2.8-2.8-2.7-2.8-2.82.8-2.8-2.8-2.8-2.52.6-2.42.5-2.0-2.2-1.8-1.91.3
Locomotion in novel chamber post-restriction1.44.15.1-2.2-2.32.1-2.1-2.1-2.2-2.3-2.32.3-2.3-2.2-1.9-2.02.1-2.22.1-2.1-1.5-1.4-1.50.8
Fecal boli incidents, locomotor time 10.00.00.20.10.10.0-0.00.00.1-0.0-0.00.0-0.0-0.30.2-0.1-0.30.40.20.40.40.20.40.1
Change in fecal boli incidents, locomotor task0.10.11.00.0-0.0-0.10.1-0.0-0.1-0.1-0.10.1-0.10.3-0.20.40.3-0.1-0.0-0.2-1.0-0.6-0.4-0.7
Time >=10cm from walls, locomotor time 10.81.03.2-0.5-0.70.8-0.8-0.8-0.7-0.7-0.70.7-0.7-0.5-0.9-0.01.1-1.11.7-0.2-1.8-1.6-1.4-1.0
Bouts of movement, locomotor time 11.41.85.91.31.5-1.41.41.31.41.41.4-1.41.41.31.20.8-1.40.9-1.40.72.41.61.5-0.0
Total resting periods, locomotor time 11.01.24.11.11.2-1.11.11.11.11.11.1-1.11.11.01.00.6-1.10.6-1.00.52.01.21.2-0.1
Rest time, locomotor task time 11.01.62.6-1.5-1.41.5-1.5-1.4-1.3-1.5-1.51.5-1.5-1.6-1.3-1.51.1-0.91.1-0.9-0.1-0.6-0.51.0
Distance moved, locomotor task time 10.10.31.40.60.3-0.50.50.40.30.20.2-0.20.20.80.40.80.0-0.10.20.3-1.0-0.7-0.8-1.2
Vertical activity count, locomotor time 10.11.01.3-1.1-1.11.0-1.0-1.0-1.1-1.1-1.11.1-1.1-1.0-1.1-0.91.0-1.01.0-1.1-1.1-0.8-0.80.3
Time >=10cm from walls, locomotor time 20.00.10.40.30.1-0.20.20.10.40.20.2-0.20.20.2-0.10.2-0.10.10.10.60.40.00.0-0.1
Bouts of movement, locomotor time 20.20.61.40.80.8-0.90.90.80.70.80.8-0.80.81.00.70.6-0.60.4-0.60.61.20.60.6-0.6
Total resting periods, locomotor time 20.10.30.80.60.5-0.60.60.50.40.50.5-0.50.50.70.40.5-0.3-0.0-0.20.30.90.20.2-0.7
Rest time, locomotor task time 21.72.93.8-1.7-1.91.9-1.9-1.9-1.7-1.9-1.91.9-1.9-1.7-1.9-1.51.8-1.71.7-1.4-0.8-1.6-1.30.3
Distance moved, locomotor task time 21.01.41.81.21.2-1.31.31.31.31.21.2-1.21.21.11.20.9-1.31.3-1.31.10.81.20.9-0.0
Vertical activity count, locomotor time 20.10.31.6-0.30.1-0.10.10.1-0.1-0.0-0.00.0-0.0-0.5-0.0-0.6-0.50.7-0.80.10.41.20.91.3
Light reinforcement 10.00.10.4-0.4-0.40.4-0.4-0.3-0.3-0.2-0.20.2-0.2-0.4-0.2-0.60.3-0.40.1-0.60.50.2-0.00.6
Light reinforcement 20.40.81.9-1.0-1.01.0-1.0-1.0-1.0-1.0-1.01.0-1.0-1.4-0.9-1.10.8-0.61.0-0.6-0.5-0.1-0.41.0
Bone: marrow area0.92.27.1-0.9-1.31.3-1.3-1.3-1.3-1.3-1.31.3-1.3-0.7-1.5-0.01.9-1.52.0-0.3-2.7-2.1-1.9-1.4
Bone: maximum diameter0.20.31.50.50.5-0.60.60.50.50.50.5-0.50.50.10.50.5-0.61.0-0.31.20.20.70.70.2
Bone: maximum force2.85.69.12.82.6-2.72.72.62.52.62.6-2.62.62.72.73.0-2.12.2-1.52.90.70.91.0-2.0
Bone: maximum moment2.75.18.42.72.5-2.62.62.52.42.42.4-2.42.42.52.52.9-2.02.1-1.52.80.70.80.9-1.9
Mean time between licks in bursts0.10.30.90.40.6-0.60.60.50.50.70.7-0.70.70.60.60.4-0.60.8-1.00.20.00.60.7-0.0
Mean num. licks in bursts0.10.41.1-0.5-0.50.7-0.7-0.6-0.5-0.7-0.70.7-0.7-0.2-0.6-0.40.8-1.00.4-0.70.1-0.6-0.6-0.0
Cd content in liver1.11.21.8-1.2-1.21.2-1.2-1.2-1.2-1.2-1.21.2-1.2-1.3-1.1-1.21.1-1.31.3-0.9-0.4-0.6-0.60.7
Co content in liver1.31.63.6-1.6-1.41.3-1.3-1.4-1.2-1.2-1.21.2-1.2-1.5-1.4-1.90.9-1.10.3-1.60.60.1-0.11.6
Cu content in liver0.10.10.80.10.0-0.10.10.1-0.2-0.2-0.20.2-0.20.30.10.20.1-0.50.4-0.7-0.1-0.8-0.7-0.9
Fe content in liver0.20.31.00.30.6-0.50.50.40.40.40.4-0.40.40.10.50.2-0.61.0-0.70.80.30.70.80.5
K content in liver0.50.51.40.80.7-0.70.70.70.60.70.7-0.70.71.00.71.1-0.50.4-0.30.6-0.1-0.2-0.3-1.2
Mg content in liver0.40.51.1-0.5-0.60.6-0.6-0.6-0.7-0.6-0.60.6-0.6-0.2-0.6-0.20.8-0.90.7-0.7-1.0-1.0-1.1-0.6
Mn content in liver3.43.84.92.12.2-2.12.12.22.12.12.1-2.12.11.72.21.8-2.12.2-1.82.01.11.61.7-0.4
Na content in liver0.60.71.90.50.7-0.70.70.70.70.70.7-0.70.70.20.70.2-1.01.3-1.01.01.41.21.10.7
Rb content in liver2.02.34.2-1.5-1.51.5-1.5-1.6-1.6-1.7-1.71.7-1.7-1.1-1.5-1.31.8-2.11.5-1.8-0.9-1.5-1.4-0.1
Se content in liver0.10.10.3-0.4-0.20.2-0.2-0.3-0.4-0.4-0.40.4-0.4-0.5-0.2-0.40.4-0.30.5-0.1-0.3-0.1-0.00.3
Sr content in liver2.92.53.71.41.6-1.61.61.61.71.71.7-1.71.71.11.61.0-1.81.8-1.81.61.91.81.60.4
Zn content in liver0.20.20.60.60.5-0.60.60.50.50.50.5-0.50.50.80.50.6-0.40.1-0.40.10.50.0-0.1-0.7
Bone: minimum diameter1.02.05.4-0.6-1.20.9-0.9-1.0-1.2-1.2-1.21.2-1.2-0.2-1.10.21.8-1.82.0-0.7-2.1-2.3-2.1-1.8
Time in familiar zone, hab. session 10.30.41.5-0.4-0.50.4-0.4-0.5-0.5-0.5-0.50.5-0.5-0.3-0.3-0.10.5-0.60.8-0.9-1.2-0.8-0.9-0.5
Time in novel zone, hab. session 10.20.21.0-0.6-0.40.5-0.5-0.5-0.4-0.4-0.40.4-0.4-0.6-0.6-0.70.3-0.1-0.2-0.00.50.30.41.0
Total zone transitions, hab. session 10.60.81.41.11.0-1.11.11.11.00.90.9-0.90.91.21.11.1-0.90.6-0.60.50.30.20.2-1.1
Total locomotion distance, hab. session 10.40.61.5-0.4-0.70.7-0.7-0.7-0.5-0.6-0.60.6-0.6-0.3-0.7-0.00.7-0.71.0-0.6-1.2-1.2-1.2-0.8
Locomotion velocity, hab. session 10.10.20.90.1-0.20.2-0.2-0.1-0.1-0.1-0.10.1-0.10.2-0.20.40.2-0.30.5-0.2-0.6-0.8-0.8-0.9
Time in familiar zone, hab. session 20.10.10.3-0.3-0.00.0-0.0-0.0-0.30.00.0-0.00.0-0.2-0.0-0.3-0.20.4-0.5-0.30.10.40.30.5
Time in novel zone, hab. session 20.10.10.70.40.2-0.20.20.20.40.20.2-0.20.20.60.20.50.1-0.50.30.3-0.1-0.4-0.4-0.8
Total zone transitions, hab. session 21.51.96.71.81.3-1.41.41.31.41.31.3-1.31.32.21.32.2-0.40.3-0.41.1-0.8-0.6-0.7-2.6
Total locomotion distance, hab. session 20.50.73.70.3-0.20.2-0.2-0.20.0-0.0-0.00.0-0.00.8-0.20.90.7-0.60.7-0.1-1.6-1.4-1.6-1.9
Locomotion velocity, hab. session 20.60.83.30.2-0.40.3-0.3-0.3-0.2-0.3-0.30.3-0.30.5-0.40.80.9-0.71.0-0.1-1.8-1.6-1.7-1.8
Novel to familiar place preference ratio0.81.01.51.21.0-1.11.11.11.21.21.2-1.21.21.01.11.1-1.00.7-0.51.00.40.60.7-0.6
Novelty place preference0.30.40.70.80.6-0.70.70.70.80.70.7-0.70.70.70.70.7-0.60.3-0.20.60.30.30.3-0.4
Time in novel zone, NPP test0.20.30.50.70.5-0.60.60.60.70.60.6-0.60.60.60.60.6-0.40.2-0.10.50.20.30.3-0.4
Total zone transitions, NPP test2.13.05.12.11.9-1.91.91.92.01.91.9-1.91.92.31.82.3-1.41.3-1.31.90.50.50.5-1.7
Total locomotion distance, NPP test0.20.31.80.50.2-0.20.20.20.30.30.3-0.30.30.70.10.90.1-0.20.20.2-0.7-0.8-0.8-1.4
Locomotion velocity, NPP test0.20.31.80.60.3-0.30.30.30.40.30.3-0.30.30.80.30.9-0.0-0.20.20.3-0.5-0.7-0.7-1.3
Intraocular pressure0.91.53.7-1.5-1.31.3-1.3-1.3-1.1-1.2-1.21.2-1.2-1.9-1.5-1.90.8-0.60.8-0.70.50.30.41.9
Delta distance traveled before/after self-admin0.20.20.6-0.5-0.30.3-0.3-0.2-0.4-0.4-0.40.4-0.4-0.4-0.3-0.70.1-0.5-0.2-0.80.70.30.30.7
Delta ambulatory time before/after self-admin0.10.10.5-0.3-0.10.1-0.1-0.0-0.2-0.2-0.20.2-0.2-0.2-0.1-0.4-0.1-0.2-0.4-0.60.70.50.40.6
Parametrial fat weight3.58.311.5-2.8-3.13.2-3.2-3.2-3.0-2.8-2.82.8-2.8-2.6-3.4-2.23.2-3.13.4-2.5-2.9-2.8-2.90.1
Pavlov. Cond. lever latency0.30.30.8-0.7-0.60.6-0.6-0.5-0.6-0.6-0.60.6-0.6-0.8-0.6-0.90.4-0.40.2-0.80.40.00.10.7
Pavlov. Cond. magazine entry latency0.30.42.10.90.5-0.40.40.40.60.60.6-0.60.61.00.41.1-0.2-0.00.20.5-0.5-0.5-0.7-1.4
Pavlov. Cond. change in total contacts0.10.10.70.50.2-0.30.30.30.30.30.3-0.30.30.50.30.6-0.30.10.30.3-0.2-0.3-0.4-0.8
Pavlov. Cond. index score0.20.30.50.70.5-0.50.50.50.50.60.6-0.60.60.60.50.6-0.50.4-0.20.70.10.2-0.0-0.4
Pavlov. Cond. latency score0.10.20.40.60.3-0.30.30.30.40.50.5-0.50.50.60.30.7-0.30.2-0.00.6-0.3-0.1-0.3-0.6
Pavlov. Cond. lever contacts0.10.20.60.50.3-0.40.40.30.30.40.4-0.40.40.60.30.7-0.20.10.00.5-0.6-0.3-0.4-0.8
Pavlov. Cond. magazine entry number0.30.40.6-0.7-0.60.6-0.6-0.6-0.6-0.7-0.70.7-0.7-0.6-0.6-0.50.8-0.50.4-0.7-0.7-0.5-0.40.1
Pavlov. Cond. intertrial magazine entries0.40.51.2-0.9-0.70.4-0.4-0.5-1.0-0.8-0.80.8-0.8-1.0-0.4-1.10.4-0.80.5-0.8-0.2-0.0-0.01.0
Pavlov. Cond. lever-magazine prob. diff.0.40.40.80.90.7-0.60.60.60.70.80.8-0.80.80.90.60.9-0.60.5-0.20.80.10.1-0.1-0.8
Pavlov. Cond. response bias0.20.30.40.60.5-0.60.60.50.50.60.6-0.60.60.50.50.5-0.70.5-0.30.60.30.40.3-0.2
Pavlov. Cond. lever latency0.60.91.6-0.9-1.01.0-1.0-1.0-1.0-1.0-1.01.0-1.0-0.6-1.0-0.81.0-1.20.7-1.2-0.8-0.9-0.9-0.0
Pavlov. Cond. magazine entry latency3.65.27.22.72.5-2.72.72.62.42.52.5-2.52.52.72.72.6-2.01.9-1.82.11.41.11.2-1.7
Pavlov. Cond. change in total contacts0.92.33.31.81.8-1.81.81.81.61.61.6-1.61.61.61.81.6-1.41.3-0.81.40.80.80.9-1.0
Pavlov. Cond. index score2.13.34.72.11.9-2.12.12.02.02.02.0-2.02.01.92.22.0-1.71.7-1.31.81.11.01.1-1.1
Pavlov. Cond. latency score1.72.84.02.01.8-2.02.01.91.81.81.8-1.81.81.72.01.9-1.61.6-1.11.70.90.91.0-1.1
Pavlov. Cond. lever contacts0.60.91.51.01.0-1.01.01.01.01.01.0-1.01.00.71.10.8-0.91.2-0.71.20.80.90.9-0.0
Pavlov. Cond. magazine entry number6.68.611.4-3.4-3.33.3-3.3-3.3-3.2-3.2-3.23.2-3.2-3.2-3.4-3.12.8-2.62.4-2.7-2.0-1.8-1.91.6
Pavlov. Cond. intertrial magazine entries0.61.31.9-1.4-1.31.3-1.3-1.3-1.3-1.3-1.31.3-1.3-1.4-1.4-1.31.1-1.01.1-1.0-0.8-0.6-0.70.8
Pavlov. Cond. lever-magazine prob. diff.2.64.05.52.32.2-2.32.32.22.22.22.2-2.22.22.12.42.2-1.91.8-1.41.91.21.21.2-1.2
Pavlov. Cond. response bias2.02.83.81.91.8-1.91.91.91.91.81.8-1.81.81.71.91.8-1.61.7-1.31.81.21.01.1-0.9
Time in closed arm before self-admin0.20.30.9-0.4-0.50.4-0.4-0.5-0.5-0.5-0.50.5-0.5-0.5-0.8-0.30.7-0.70.9-0.5-0.9-0.6-0.6-0.1
Time in closed arm after self-admin0.20.31.1-0.5-0.40.3-0.3-0.4-0.6-0.5-0.50.5-0.5-0.4-0.6-0.30.5-0.50.5-0.8-1.0-0.4-0.5-0.1
Time in open arm before self-admin0.20.20.8-0.5-0.60.7-0.7-0.6-0.4-0.4-0.40.4-0.4-0.1-0.2-0.40.4-0.5-0.1-0.9-0.4-0.5-0.7-0.0
Time in open arm after self-admin0.10.11.10.20.1-0.10.10.10.30.30.3-0.30.30.20.20.0-0.20.1-0.50.31.00.20.30.2
Bone: periosteal estimation0.10.20.90.2-0.0-0.10.10.0-0.1-0.0-0.00.0-0.00.1-0.00.60.20.20.50.9-0.9-0.5-0.4-0.8
Bone: periosteal perimeter0.10.20.80.60.3-0.50.50.40.40.40.4-0.40.40.50.40.9-0.20.40.10.9-0.5-0.2-0.1-0.8
Bone: post-yield work1.52.514.91.70.8-0.90.90.90.80.80.8-0.80.82.00.92.60.2-0.41.21.0-2.4-2.1-2.1-3.9
Progressive ratio test 1 active lever presses0.10.20.6-0.5-0.80.3-0.3-0.4-0.6-0.5-0.50.5-0.5-0.6-0.2-0.40.7-0.50.7-0.1-0.5-0.4-0.50.3
Progressive ratio test 1 breakpoint0.10.20.5-0.4-0.70.3-0.3-0.4-0.5-0.4-0.40.4-0.4-0.6-0.1-0.40.6-0.40.6-0.1-0.4-0.3-0.50.3
Progressive ratio test 1 inactive lever presses0.00.10.2-0.3-0.40.3-0.3-0.2-0.3-0.2-0.20.2-0.2-0.4-0.1-0.40.3-0.40.3-0.30.2-0.1-0.00.3
Progressive ratio test 2 active lever presses1.72.43.6-1.7-1.91.5-1.5-1.6-1.8-1.5-1.51.5-1.5-1.9-1.4-1.61.8-1.61.9-1.3-1.4-1.1-1.30.9
Progressive ratio test 2 breakpoint1.82.33.7-1.7-1.91.5-1.5-1.6-1.7-1.5-1.51.5-1.5-1.9-1.3-1.61.7-1.51.8-1.3-1.4-1.1-1.20.9
Progressive ratio test 2 inactive lever presses3.09.412.1-3.3-3.33.2-3.2-3.2-3.3-3.2-3.23.2-3.2-3.4-3.1-3.13.4-3.43.5-3.0-2.4-2.5-2.31.3
Incentive Sensitization - Responses0.00.10.90.1-0.1-0.10.10.0-0.10.10.1-0.10.10.00.10.30.3-0.20.50.1-1.0-0.5-0.6-0.5
Incentive Sensitization - Breakpoint0.10.21.1-0.1-0.40.1-0.1-0.2-0.3-0.1-0.10.1-0.1-0.2-0.10.00.4-0.40.7-0.1-1.0-0.6-0.7-0.3
Sum of active levers in priming session hrs 5-62.42.37.20.71.2-1.21.21.21.01.01.0-1.01.0-0.11.5-0.0-2.02.2-1.51.41.82.72.61.8
Progressive ratio0.51.55.91.61.1-0.90.91.01.21.01.0-1.01.01.90.92.1-0.30.40.01.3-0.9-1.1-0.9-2.4
Food seeking constrained by brief footshock0.10.10.20.20.4-0.30.30.40.20.20.2-0.20.20.30.40.2-0.40.4-0.3-0.0-0.30.30.2-0.0
Seeking ratio, punishment vs. effort0.71.63.9-1.8-1.31.1-1.1-1.2-1.4-1.3-1.31.3-1.3-1.7-1.1-2.00.7-0.80.3-1.80.00.30.21.9
Retroperitoneal fat weight8.739.247.7-6.8-6.86.8-6.8-6.9-6.7-6.8-6.86.8-6.8-6.4-6.8-5.96.7-6.36.2-5.7-5.2-4.9-5.02.2
Reaction time number correct0.10.51.60.40.5-0.60.60.50.80.50.5-0.50.50.10.60.2-0.81.3-1.00.70.81.10.90.8
Reaction time mean minus median0.74.25.92.42.3-2.32.32.32.22.22.2-2.22.22.12.12.2-2.22.3-1.62.31.11.41.6-1.1
Reaction time mean minus median AUC0.32.33.71.61.6-1.71.71.61.61.61.6-1.61.61.31.51.3-1.71.9-1.41.71.11.31.6-0.3
Reaction time num false alarms0.20.31.2-0.7-0.70.6-0.6-0.5-0.8-0.4-0.40.4-0.4-0.5-0.4-0.60.4-0.60.2-1.1-0.5-0.3-0.40.1
Reaction time num false alarms AUC0.00.00.2-0.10.1-0.10.10.1-0.10.10.1-0.10.10.10.2-0.0-0.20.1-0.4-0.5-0.20.0-0.1-0.2
Reaction time trials correct on left0.10.51.60.40.5-0.60.60.50.80.50.5-0.50.50.10.60.2-0.81.3-1.00.70.81.10.90.8
Reaction time trials on left0.20.62.00.50.6-0.70.70.60.90.60.6-0.60.60.20.70.3-1.01.4-1.10.80.81.21.00.8
Reaction time mean0.00.10.10.30.2-0.20.20.20.20.40.4-0.40.40.2-0.10.1-0.30.20.10.30.20.20.3-0.2
Reaction time mean AUC0.00.00.10.30.1-0.10.10.20.10.30.3-0.30.30.2-0.10.2-0.20.00.20.10.10.00.1-0.4
Median of all reaction times0.10.10.4-0.3-0.40.5-0.5-0.4-0.4-0.2-0.20.2-0.2-0.2-0.6-0.30.4-0.50.6-0.3-0.2-0.3-0.3-0.1
Reaction time omissions1.52.53.71.81.8-1.91.91.81.71.61.6-1.61.61.71.61.6-1.71.8-1.41.51.00.91.2-0.7
Reaction time false alarm rate0.20.30.9-0.6-0.50.5-0.5-0.4-0.8-0.4-0.40.4-0.4-0.3-0.4-0.40.5-0.70.4-0.9-0.7-0.7-0.6-0.4
Reaction time premature initiation rate2.13.35.21.82.0-1.81.81.91.91.91.9-1.91.91.91.81.7-1.92.1-2.31.81.41.51.6-0.6
Reaction time premature initiations1.85.69.22.22.5-2.32.32.42.62.42.4-2.42.42.12.41.8-2.63.0-3.02.22.32.32.3-0.1
Std. dev. reaction times0.41.21.71.31.3-1.21.21.21.31.21.2-1.21.21.10.91.1-1.21.2-0.81.20.60.91.1-0.5
Reaction time trials completed0.20.62.00.50.6-0.70.70.60.90.60.6-0.60.60.20.70.3-1.01.4-1.10.80.81.21.00.8
Reaction time trials AUC0.10.41.40.30.4-0.50.50.50.70.50.5-0.50.50.10.50.2-0.81.2-0.90.60.61.00.80.7
Run reversals in cocaine runway, females0.60.73.20.80.5-0.60.60.50.60.60.6-0.60.61.20.41.3-0.10.1-0.0-0.1-1.2-1.0-1.1-1.8
Run reversals in cocaine runway, males0.50.63.1-0.9-0.60.6-0.6-0.6-0.6-0.6-0.60.6-0.6-1.3-0.5-1.2-0.10.3-0.2-0.20.60.80.71.8
Latency to leave start box in cocaine runway0.30.41.40.0-0.20.0-0.0-0.1-0.4-0.4-0.40.4-0.40.2-0.10.40.5-0.70.8-0.4-1.2-1.1-1.2-1.1
Latency to leave start box in cocaine runway, F0.20.21.10.1-0.2-0.00.0-0.1-0.1-0.2-0.20.2-0.20.3-0.00.30.4-0.70.6-0.3-0.4-1.0-1.0-0.9
Latency to leave start box in cocaine runway, M0.10.11.10.20.3-0.40.40.3-0.1-0.0-0.00.0-0.00.10.20.5-0.10.30.10.2-1.1-0.1-0.2-0.5
Std. dev. time between licks in bursts0.00.00.2-0.3-0.20.1-0.1-0.2-0.2-0.1-0.10.1-0.1-0.2-0.2-0.30.00.3-0.5-0.2-0.20.20.20.4
Total sessions with >9 infusions0.20.31.40.2-0.1-0.20.20.1-0.00.00.0-0.00.00.30.20.60.5-0.40.60.3-1.2-1.0-1.0-0.9
Short access day 1 total inactive lever presses1.32.73.6-1.7-1.61.7-1.7-1.6-1.8-1.7-1.71.7-1.7-1.6-1.6-1.41.7-1.71.7-1.9-1.6-1.6-1.40.4
Short access day 10 total inactive lever presses0.10.72.9-0.9-0.80.8-0.8-0.7-0.9-0.9-0.90.9-0.9-0.7-0.7-0.80.7-0.90.7-1.7-0.5-0.7-0.60.2
Short access day 1 total infusions1.12.24.7-1.2-1.51.3-1.3-1.4-1.5-1.4-1.41.4-1.4-1.0-1.2-0.71.8-1.71.9-1.3-2.2-2.1-2.0-0.5
Short access day 10 total infusions0.81.45.8-0.2-0.80.3-0.3-0.5-0.7-0.7-0.70.7-0.7-0.0-0.20.41.4-1.41.7-0.6-2.4-2.2-2.3-1.5
Short access total infusions0.71.05.0-0.4-0.80.5-0.5-0.6-0.7-0.7-0.70.7-0.7-0.3-0.30.21.2-1.01.3-0.5-2.2-1.7-1.8-1.0
Short access day 1 locomotion1.22.03.4-1.3-1.51.3-1.3-1.3-1.5-1.4-1.41.4-1.4-1.2-1.0-1.01.6-1.61.7-1.7-1.8-1.7-1.6-0.0
Short access day 10 total locomotion0.41.53.0-0.9-1.31.2-1.2-1.1-1.1-1.1-1.11.1-1.1-0.9-0.9-0.61.4-1.41.7-1.0-1.6-1.7-1.7-0.4
Short access total locomotion1.21.93.5-1.1-1.41.3-1.3-1.3-1.4-1.3-1.31.3-1.3-1.1-1.0-0.81.6-1.61.8-1.2-1.9-1.8-1.8-0.3
One hour access (0.3 mA shock)6.47.610.0-3.0-3.22.9-2.9-2.9-3.0-2.9-2.92.9-2.9-3.1-2.8-2.73.0-2.92.9-2.5-2.2-2.1-2.21.3
Compulsive drug intake1.52.24.51.31.4-1.41.41.41.51.51.5-1.51.51.51.31.0-1.61.6-2.11.32.11.71.60.0
One hour access (shock baseline)3.38.711.5-3.1-3.33.0-3.0-3.1-3.2-3.1-3.13.1-3.1-3.3-2.9-2.83.2-3.13.4-2.7-2.6-2.4-2.41.2
Social response proportion0.60.71.20.91.1-1.01.01.00.90.90.9-0.90.90.80.80.8-0.90.8-0.70.90.70.80.9-0.2
Social responses0.30.30.80.40.5-0.50.50.60.50.50.5-0.50.50.30.60.2-0.60.7-0.70.60.80.80.90.5
Social time0.30.51.00.50.6-0.60.60.60.90.50.5-0.50.50.40.60.3-0.71.0-1.00.80.90.90.90.5
Soleus weight4.011.915.3-3.8-3.83.9-3.9-3.9-3.7-3.8-3.83.8-3.8-3.7-3.9-3.43.5-3.43.3-2.9-2.3-2.5-2.61.5
Bone: stiffness2.13.86.32.42.1-2.22.22.12.12.22.2-2.22.22.32.12.5-1.61.6-1.12.20.80.70.7-1.7
Tibialis anterior weight10.335.348.26.16.5-6.46.46.36.46.36.3-6.36.35.26.45.3-6.66.9-6.16.54.75.15.1-0.8
Time to tail flick, vehicle, before self-admin0.20.20.70.60.3-0.40.40.30.50.50.5-0.50.50.60.30.8-0.10.1-0.00.1-0.8-0.2-0.3-0.8
Time to tail flick, vehicle, after self-admin0.40.84.51.10.6-0.50.50.60.80.70.7-0.70.71.40.51.6-0.00.20.00.8-1.0-1.1-0.9-2.1
Time to tail flick, test, before self-admin2.42.75.2-1.3-1.51.7-1.7-1.5-1.5-1.4-1.41.4-1.4-0.8-1.4-0.61.9-2.11.9-2.0-2.3-2.3-2.3-1.0
Time to tail flick, test, after self-admin0.10.10.30.10.2-0.10.10.10.30.20.2-0.20.2-0.10.00.0-0.20.2-0.20.10.20.60.50.4
Delta time to tail flick, vehicle, before/after SA0.30.31.40.70.6-0.50.50.50.60.50.5-0.50.50.90.51.0-0.30.3-0.30.70.0-0.4-0.2-1.2
Delta time to tail flick, test, before/after SA2.53.18.61.01.4-1.41.41.31.51.41.4-1.41.40.41.20.1-2.02.2-2.11.92.72.92.91.9
Tibia length1.23.35.81.61.7-1.91.91.91.81.81.8-1.81.80.91.91.1-2.12.3-1.52.41.82.12.20.6
Ambulatory time before self-admin0.20.50.80.90.8-0.80.80.70.70.80.8-0.80.80.80.70.9-0.50.3-0.00.80.20.10.2-0.8
Ambulatory time after self-admin0.20.31.5-0.3-0.30.3-0.3-0.4-0.4-0.4-0.40.4-0.4-0.2-0.5-0.20.5-1.20.8-0.80.2-0.5-0.5-0.3
Bone: tissue strength0.00.00.10.10.1-0.10.10.10.00.10.1-0.10.10.10.10.1-0.0-0.10.10.1-0.3-0.1-0.1-0.2
Total heroin consumption5.26.17.72.72.7-2.62.62.62.72.72.7-2.72.72.62.82.4-2.62.6-2.32.32.12.01.8-1.1
Bone: trabecular number0.61.22.71.41.0-1.31.31.21.11.11.1-1.11.11.51.31.7-0.50.4-0.21.20.2-0.2-0.0-1.5
Bone: trabecular spacing0.40.61.2-0.9-0.80.9-0.9-0.9-0.7-0.8-0.80.8-0.8-0.7-0.8-0.90.7-0.60.4-1.1-0.4-0.4-0.50.3
Bone: trabecular thickness0.40.51.3-0.4-0.60.4-0.4-0.5-0.6-0.7-0.70.7-0.7-0.2-0.5-0.10.8-1.01.0-0.7-0.7-1.1-1.0-0.7
Bone: trabecular tissue density3.35.78.1-2.8-2.52.7-2.7-2.7-2.7-2.6-2.62.6-2.6-2.8-2.6-2.82.2-2.22.1-2.4-1.2-1.3-1.21.6
Water consumed over 24 hours0.61.22.61.11.2-1.21.21.21.31.21.2-1.21.21.21.30.8-1.00.8-1.30.81.61.01.0-0.1
Number of responses in last shaping day0.00.00.4-0.2-0.30.0-0.0-0.1-0.1-0.0-0.00.0-0.0-0.1-0.1-0.30.10.0-0.2-0.10.60.30.20.4