Aldh3b2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL mRNA stability Aldh3b2 0.17 0.1 2.0e-13 0.11 0.13 0.13 0.13 2.5e-12 4.7e-14 6.0e-14 4.4e-14
2 NAcc isoform ratio XM_039101313.1 0.03 0.02 7.1e-04 0.01 0.02 0.02 0.02 2.3e-03 3.2e-04 1.3e-03 3.8e-04
3 PL isoform ratio XM_039101313.1 0.12 0.08 5.4e-09 0.08 0.08 0.08 0.08 8.9e-09 2.3e-09 9.2e-09 4.6e-09
4 PL gene expression Aldh3b2 0.42 0.2 0.0e+00 0.33 0.34 0.34 0.34 9.9e-37 3.9e-38 9.8e-38 2.3e-38
5 BLA gene expression Aldh3b2 0.3 0.14 3.8e-15 0.23 0.26 0.25 0.25 1.2e-12 8.3e-14 2.3e-13 2.5e-13
6 OFC gene expression Aldh3b2 0.64 0.17 1.5e-11 0.38 0.24 0.34 0.35 6.5e-10 2.2e-06 7.1e-09 3.6e-09
7 IC gene expression Aldh3b2 0.73 0.2 0.0e+00 0.33 0.39 0.39 0.39 1.1e-14 1.1e-17 1.1e-17 1.2e-17
8 Brain gene expression Aldh3b2 0.37 0.19 0.0e+00 0.26 0.26 0.28 0.26 1.8e-24 4.8e-24 1.1e-25 1.3e-24
9 IC mRNA stability Aldh3b2 0.23 0.13 1.2e-05 0.1 0.08 0.11 0.08 4.2e-05 2.6e-04 3.4e-05 2.3e-04
10 IL gene expression Aldh3b2 0.27 0.16 1.5e-03 0.13 0.13 0.19 0.16 6.4e-04 5.4e-04 2.1e-05 1.3e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density3.05.17.41.5-2.2-2.52.72.72.02.62.42.01.8
Area under the delay curve0.91.11.90.5-0.7-1.01.31.21.41.21.11.00.7
BMI with tail3.311.315.23.3-3.5-3.63.43.23.93.23.53.32.5
BMI without tail1.44.36.92.6-2.6-2.42.01.72.11.72.11.81.3
Body weight1.67.215.74.0-3.7-3.32.41.72.51.62.31.82.5
Weight adjusted by age0.20.31.21.1-0.8-0.50.2-0.10.1-0.20.2-0.00.8
Bone surface4.58.311.02.9-3.2-3.33.12.82.62.72.92.42.7
Bone volume2.64.66.11.7-2.2-2.42.52.42.02.32.21.91.9
Breakpoint value in progressive ratio session1.01.23.01.7-1.5-1.40.90.60.90.40.80.91.1
Number of licking bursts0.10.10.50.1-0.3-0.40.40.40.10.30.10.20.7
Context. condit. distance diff. score0.20.21.1-1.00.70.5-0.10.1-0.00.2-0.0-0.0-0.3
Locomotion velocity, session 10.00.00.00.0-0.1-0.10.10.10.10.10.1-0.00.2
Locomotion distance, session 11.92.43.01.2-1.5-1.71.71.71.61.61.61.51.4
Locomotion velocity, session 20.70.82.61.6-1.4-1.10.60.30.60.20.60.40.8
Locomotion distance, session 21.11.52.11.4-1.5-1.41.21.01.21.01.21.01.2
Locomotion velocity, session 31.61.82.70.6-1.0-1.31.51.61.61.61.51.41.0
Locomotion distance, session 30.20.20.30.2-0.3-0.30.40.40.60.50.60.30.3
Stereotopy head waving bouts, day 30.91.12.00.1-0.5-0.81.21.41.21.41.21.30.4
Stereotopy head waving duration, day 30.30.30.8-0.60.2-0.10.60.80.50.90.40.8-0.1
Locomotion velocity, session 71.01.11.70.6-0.8-1.01.21.21.31.31.31.20.6
Locomotion distance, session 70.40.50.70.8-0.8-0.80.70.60.70.60.70.60.5
Stereotopy head waving bouts, day 71.11.22.20.1-0.6-0.91.31.41.21.51.11.40.2
Stereotopy head waving duration, day 71.82.22.91.0-1.5-1.61.71.61.51.61.51.60.9
Locomotion velocity, session 80.50.61.51.2-1.2-1.00.60.40.50.20.50.30.9
Locomotion distance, session 80.10.20.4-0.4-0.0-0.20.40.60.40.60.40.40.3
Degree of sensitization distance0.60.60.80.8-0.9-0.90.80.70.80.70.80.80.6
Degree of sensitization stereotypy0.70.81.20.5-0.9-1.01.11.00.91.00.91.00.5
Conditioned locomotion0.80.92.20.8-0.30.2-0.9-1.3-1.0-1.5-1.1-1.20.2
Cocaine response after cond. corrected0.00.00.1-0.20.10.00.10.20.20.20.10.3-0.3
Cocaine response after cond. not corrected0.20.20.5-0.0-0.1-0.30.50.60.50.60.40.7-0.1
Cocaine response before conditioning0.10.10.20.2-0.4-0.40.50.40.20.40.20.40.4
Saline control response1.01.43.61.9-1.8-1.51.00.60.60.40.60.61.3
Bone: connectivity density4.97.710.52.6-3.1-3.23.12.92.32.72.82.32.5
Bone: cortical apparent density0.10.20.50.4-0.10.1-0.5-0.6-0.4-0.7-0.3-0.60.1
Bone: cortical area0.20.30.70.4-0.20.1-0.5-0.7-0.6-0.8-0.8-0.60.2
Bone: cortical porosity0.10.10.40.2-0.3-0.30.30.30.50.30.10.60.1
Bone: cortical porosity0.10.10.30.5-0.5-0.40.30.20.40.10.10.50.3
Bone: cortical thickness1.01.63.51.7-0.9-0.2-1.0-1.6-1.1-1.9-1.3-1.40.7
Bone: cortical thickness0.40.41.31.1-0.8-0.4-0.2-0.5-0.7-0.7-0.4-0.70.6
Bone: cortical tissue density0.10.20.50.6-0.20.0-0.5-0.6-0.3-0.7-0.3-0.60.2
Condit. Reinf. active minus inactive responses0.50.60.80.6-0.7-0.80.80.80.90.80.90.70.5
Condit. Reinf. active-inactive response ratio0.20.20.50.2-0.3-0.40.50.60.60.60.70.50.2
Condit. Reinf. active responses0.00.10.10.2-0.1-0.20.20.20.30.30.40.30.0
Condit. Reinf. inactive responses0.10.10.2-0.30.40.4-0.4-0.3-0.3-0.3-0.3-0.2-0.5
Incentive salience index mean0.40.40.60.6-0.7-0.70.70.70.70.60.80.60.6
Condit. Reinf. lever presses0.00.00.00.1-0.00.0-0.1-0.1-0.2-0.2-0.1-0.20.2
Condit. Reinf. active minus inactive responses0.70.91.8-0.1-0.3-0.61.01.21.21.31.21.10.2
Condit. Reinf. active-inactive response ratio0.30.31.0-1.00.60.30.30.60.50.80.50.5-0.4
Condit. Reinf. active responses1.42.03.00.6-1.0-1.31.61.71.71.71.61.60.7
Condit. Reinf. inactive responses1.51.92.51.4-1.6-1.61.51.31.41.31.41.31.1
Condit. Reinf. lever presses1.42.02.51.2-1.5-1.61.61.41.41.41.31.41.3
Condit. Reinf. lever reinforcers received1.72.43.30.8-1.2-1.51.71.81.81.81.81.70.9
Conditioned reinforcement - actives0.61.01.4-0.81.11.2-1.1-1.1-0.8-1.0-1.0-0.4-1.1
Conditioned reinforcement - inactives0.60.93.0-1.71.51.1-0.6-0.1-0.50.1-0.30.1-1.2
Conditioned locomotion4.35.612.9-3.63.43.0-2.1-1.5-1.8-1.3-1.9-1.5-2.3
Patch foraging indifference point 0 sec0.10.20.9-0.60.40.3-0.10.10.00.2-0.20.2-0.9
Patch foraging indifference point AUC0.20.20.60.7-0.3-0.0-0.5-0.70.1-0.7-0.4-0.20.6
Delay disc. indifference point, 0s delay1.92.03.60.5-1.0-1.31.51.71.91.81.41.80.8
Delay disc. indifference point, 16s delay0.20.20.9-1.00.70.50.00.20.30.3-0.20.2-0.4
Delay disc. indifference point, 2s delay0.30.30.7-0.30.0-0.30.60.80.80.80.60.50.4
Delay disc. indifference point, 24s delay0.20.20.3-0.00.20.3-0.3-0.5-0.4-0.5-0.6-0.4-0.6
Delay disc. indifference point, 4s delay0.80.81.70.6-0.7-0.81.00.91.30.91.00.70.9
Delay disc. indifference point, 8s delay0.40.50.90.5-0.6-0.70.90.80.90.80.70.70.2
Indifference point function ln k1.32.45.9-2.42.21.8-1.0-0.6-1.4-0.4-1.0-0.8-2.0
Indifference point function log k1.32.45.9-2.42.21.8-1.0-0.6-1.4-0.4-1.0-0.8-2.0
Patch foraging total patch changes 0 sec0.20.31.0-0.60.50.5-0.4-0.4-0.4-0.4-0.6-0.3-1.0
Patch foraging total patch changes 12 sec0.70.93.01.7-1.5-1.20.60.30.90.10.50.61.0
Patch foraging total patch changes 18 sec0.20.30.60.6-0.6-0.60.40.40.70.30.30.50.8
Patch foraging total patch changes 24 sec0.10.20.70.8-0.5-0.2-0.2-0.4-0.1-0.5-0.1-0.30.2
Patch foraging total patch changes 6 sec0.91.42.01.4-1.4-1.41.11.01.31.00.91.20.8
Patch foraging time to switch 0 sec2.55.16.42.1-2.4-2.52.52.42.12.22.21.92.3
Patch foraging water rate 0 sec4.59.512.5-3.33.53.5-3.2-2.9-3.0-2.7-3.0-2.5-3.0
Patch foraging water rate 12 sec5.411.216.4-3.84.14.0-3.4-3.0-3.1-2.7-3.0-2.8-3.2
Patch foraging water rate 18 sec1.11.82.9-1.71.71.6-1.2-1.1-1.4-1.0-1.2-1.0-1.4
Patch foraging water rate 24 sec3.95.57.0-2.32.62.7-2.5-2.3-2.2-2.1-2.3-1.9-2.5
Patch foraging water rate 6 sec3.44.96.1-2.12.42.5-2.3-2.2-2.4-2.1-2.2-2.1-1.8
Seeking ratio, delayed vs. immediate footshock0.91.11.90.6-0.7-0.91.11.21.41.21.11.20.6
Distance traveled before self-admin0.40.50.70.5-0.6-0.70.80.80.60.80.80.90.6
Distance traveled after self-admin0.00.00.10.2-0.2-0.20.30.2-0.40.10.1-0.10.3
Extensor digitorum longus weight1.56.024.14.9-3.9-2.91.00.01.3-0.41.00.42.9
Bone: elastic displacement2.52.94.6-0.91.41.7-2.0-2.1-1.5-2.1-1.9-1.6-1.3
Bone: elastic work0.40.61.31.0-0.5-0.0-0.7-1.0-0.5-1.2-0.7-0.80.3
Bone: endosteal estimation0.40.92.0-1.00.4-0.10.81.21.01.40.81.2-0.2
Bone: endosteal perimeter0.81.84.0-1.40.7-0.01.21.71.42.01.21.8-0.5
Epididymis fat weight1.55.115.0-3.93.52.9-1.7-1.0-1.7-0.6-1.7-0.9-2.1
Delta time in closed arm before/after self-admin0.20.20.70.8-0.6-0.4-0.1-0.30.4-0.40.00.30.3
Delta time in open arm before/after self-admin0.20.20.50.2-0.3-0.50.60.70.30.70.50.5-0.3
Diff in mean of infusions in LGA sessions0.10.10.60.8-0.6-0.40.1-0.1-0.2-0.2-0.1-0.00.4
Delay discount exponential model param0.70.81.4-0.50.70.9-1.1-1.1-1.2-1.0-1.0-0.8-0.7
Extinction: sum of active levers before priming2.02.23.51.8-1.9-1.81.51.21.01.11.41.71.1
Active lever presses in extinction session 60.30.31.11.1-0.6-0.40.0-0.30.3-0.40.2-0.40.7
Bone: final force0.71.12.31.5-1.5-1.41.00.70.70.60.80.51.4
Bone: final moment0.61.02.21.5-1.5-1.30.90.70.60.50.70.51.3
Food consumed during 24 hour testing period0.40.60.9-0.90.90.8-0.7-0.7-1.0-0.7-1.0-0.6-0.5
Glucose0.81.33.2-0.70.1-0.41.21.71.11.81.41.20.3
Heart weight1.01.63.00.1-0.7-1.11.51.71.31.71.31.50.8
Delay discount hyperbolic model param0.80.91.5-0.50.70.9-1.1-1.1-1.2-1.1-1.1-0.8-0.7
Intermittent access intake day 1-15 change1.02.15.1-2.32.11.8-1.2-0.8-1.4-0.8-1.3-0.8-1.0
Intermittent access intake escalation1.02.14.6-2.22.01.8-1.2-0.9-1.5-0.8-1.3-0.9-1.0
Intermittent access intake escalation 21.11.33.4-1.81.71.5-1.0-0.6-1.0-0.5-1.0-0.7-0.7
Intermitt. access day 1 inactive lever presses0.00.10.9-0.10.10.1-0.1-0.10.2-0.0-0.00.5-1.0
Intermitt. access day 15 inactive lever presses0.20.40.9-0.90.60.20.40.70.20.90.40.9-0.4
Intermitt. access escalation Index1.92.64.9-2.22.12.0-1.6-1.3-1.3-1.2-1.6-1.3-1.1
Intermittent access day 1 total infusions1.22.04.5-0.4-0.2-0.81.52.01.52.11.62.00.1
Intermittent access day 15 total infusions0.91.45.6-2.42.01.3-0.30.3-0.40.5-0.30.3-1.2
Intermittent access terminal intake (last 3 days)0.70.93.1-1.71.30.70.30.90.41.10.30.8-0.7
Intermittent access total infusions0.60.71.5-1.10.70.20.61.10.81.20.71.0-0.3
Intermittent access day 1 locomotion0.70.81.8-0.30.1-0.40.81.21.21.31.01.3-0.3
Intermittent access day 15 total locomotion0.61.04.7-2.21.81.2-0.20.4-0.20.5-0.20.1-0.6
Intermittent access total locomotion1.01.25.2-2.31.81.10.00.80.31.00.20.8-0.6
Intermittent access standard deviation0.10.20.8-0.90.80.5-0.20.1-0.30.1-0.1-0.4-0.2
Left kidney weight0.31.24.4-2.11.81.4-0.6-0.3-0.5-0.0-0.8-0.1-1.1
Right kidney weight0.42.04.3-2.11.91.7-1.2-1.0-1.3-0.8-1.5-0.8-1.4
Cocaine induced anxiety0.00.10.1-0.1-0.2-0.20.30.40.00.30.30.00.2
Post-drug Anxiety0.20.20.60.7-0.8-0.70.50.40.10.40.50.10.4
Baseline Anxiety0.10.10.50.7-0.5-0.30.0-0.2-0.1-0.20.1-0.20.2
Tail length0.20.81.71.0-0.5-0.0-0.7-1.2-1.0-1.3-0.9-1.1-0.1
Length with tail0.31.55.92.4-1.9-1.20.1-0.7-0.2-1.0-0.2-0.71.4
Length without tail0.41.24.92.2-1.8-1.20.3-0.30.2-0.50.1-0.21.4
Times rat made contact with spout0.91.11.40.9-1.2-1.21.21.00.91.01.01.00.9
Lifetime Intake0.40.51.1-0.70.50.10.50.90.81.10.71.0-0.4
Liver weight, left0.81.31.8-1.11.21.3-1.2-1.1-1.3-1.1-1.2-1.1-1.0
Liver weight, right1.01.82.7-1.61.61.5-1.2-1.0-1.4-0.9-1.2-1.1-1.3
Locomotor activity0.91.42.2-1.31.31.3-1.1-1.0-1.5-0.9-1.2-1.2-1.2
Locomotor testing distance0.91.72.3-1.51.51.5-1.1-1.1-1.5-0.9-1.3-1.1-1.4
Locomotor testing rearing0.10.10.6-0.80.60.40.10.3-0.10.40.20.2-0.3
Locomotion in novel chamber1.31.76.2-2.52.11.5-0.60.0-1.10.2-0.6-0.4-1.4
Locomotion in novel chamber post-restriction0.91.44.8-2.21.81.5-0.8-0.3-0.8-0.1-0.8-0.2-1.3
Fecal boli incidents, locomotor time 10.10.10.3-0.30.30.20.0-0.10.30.0-0.20.4-0.5
Change in fecal boli incidents, locomotor task0.10.10.20.4-0.4-0.40.40.30.40.30.4-0.10.2
Time >=10cm from walls, locomotor time 11.01.12.5-0.50.0-0.41.11.41.11.61.21.50.2
Bouts of movement, locomotor time 10.30.41.10.4-0.20.2-0.6-0.9-0.2-0.9-0.7-1.10.3
Total resting periods, locomotor time 10.40.41.00.00.10.4-0.7-0.9-0.4-0.9-0.8-1.00.1
Rest time, locomotor task time 11.82.23.4-1.81.81.8-1.4-1.2-1.5-1.1-1.5-1.4-1.3
Distance moved, locomotor task time 11.01.52.00.8-1.1-1.31.31.41.21.41.31.41.0
Vertical activity count, locomotor time 10.10.20.5-0.60.2-0.10.50.70.20.70.30.3-0.2
Time >=10cm from walls, locomotor time 20.20.20.4-0.50.60.7-0.6-0.6-0.2-0.5-0.4-0.4-0.3
Bouts of movement, locomotor time 20.20.31.00.7-0.5-0.40.1-0.00.8-0.00.21.0-0.4
Total resting periods, locomotor time 20.20.31.60.4-0.4-0.40.20.10.90.20.21.3-0.4
Rest time, locomotor task time 20.30.41.4-1.20.80.40.20.60.20.70.00.8-0.4
Distance moved, locomotor task time 20.30.41.20.6-0.20.0-0.5-0.7-0.7-0.8-0.4-1.10.1
Vertical activity count, locomotor time 21.62.23.9-0.50.91.2-1.5-1.8-1.7-1.8-1.6-2.0-1.3
Light reinforcement 10.30.81.5-1.11.21.1-0.9-0.7-0.8-0.7-0.9-0.7-0.5
Light reinforcement 21.32.03.9-1.92.01.8-1.3-1.0-1.1-0.8-1.1-1.0-1.3
Bone: marrow area0.40.92.0-1.00.5-0.00.91.21.01.40.91.2-0.2
Bone: maximum diameter0.10.20.4-0.60.50.5-0.4-0.4-0.5-0.3-0.7-0.2-0.3
Bone: maximum force2.74.86.02.1-2.4-2.52.32.12.32.02.22.01.9
Bone: maximum moment2.44.25.32.1-2.3-2.32.11.92.11.82.01.91.9
Mean time between licks in bursts0.10.20.70.8-0.7-0.50.20.10.3-0.00.20.00.5
Mean num. licks in bursts0.10.20.30.3-0.3-0.30.40.30.50.40.50.5-0.2
Cd content in liver0.50.52.0-1.41.20.9-0.4-0.1-0.30.0-0.2-0.1-0.7
Co content in liver2.22.63.3-1.01.51.7-1.8-1.8-1.7-1.8-1.6-1.7-1.1
Cu content in liver0.00.00.1-0.00.20.2-0.2-0.2-0.0-0.1-0.1-0.2-0.2
Fe content in liver0.00.00.20.5-0.3-0.20.0-0.00.1-0.10.1-0.10.1
K content in liver0.70.70.90.9-0.9-0.90.90.80.80.70.80.70.7
Mg content in liver0.10.10.4-0.30.1-0.10.40.50.30.60.40.5-0.0
Mn content in liver0.80.82.51.6-1.4-1.10.60.40.70.20.60.41.0
Na content in liver0.70.81.1-0.50.70.8-1.0-1.0-1.0-1.1-1.0-1.0-0.4
Rb content in liver0.40.51.2-0.60.2-0.10.80.90.71.10.70.80.0
Se content in liver0.20.30.6-0.1-0.1-0.30.60.70.60.80.70.70.2
Sr content in liver0.40.40.80.9-0.4-0.1-0.5-0.8-0.5-0.9-0.5-0.70.3
Zn content in liver0.10.10.30.4-0.10.1-0.4-0.5-0.4-0.6-0.3-0.5-0.0
Bone: minimum diameter0.91.73.6-0.4-0.2-0.71.41.71.71.91.31.90.2
Time in familiar zone, hab. session 10.10.10.3-0.40.20.00.30.40.40.50.50.3-0.1
Time in novel zone, hab. session 10.10.10.2-0.00.00.1-0.2-0.2-0.4-0.3-0.4-0.1-0.1
Total zone transitions, hab. session 10.30.40.80.8-0.9-0.80.60.50.40.40.40.50.9
Total locomotion distance, hab. session 10.10.10.3-0.60.50.30.00.2-0.10.2-0.10.2-0.2
Locomotion velocity, hab. session 10.00.00.0-0.20.20.1-0.00.1-0.10.1-0.10.10.0
Time in familiar zone, hab. session 20.20.30.60.3-0.10.1-0.5-0.7-0.5-0.8-0.5-0.70.2
Time in novel zone, hab. session 20.90.91.50.3-0.6-0.81.11.21.11.21.01.20.3
Total zone transitions, hab. session 24.86.17.42.0-2.5-2.72.72.62.62.62.62.51.9
Total locomotion distance, hab. session 21.21.62.40.6-0.9-1.21.41.51.41.61.41.50.8
Locomotion velocity, hab. session 20.91.22.20.3-0.6-0.91.31.41.21.51.21.40.6
Novel to familiar place preference ratio0.50.50.70.5-0.7-0.80.80.80.70.80.70.80.6
Novelty place preference0.40.40.70.3-0.5-0.60.80.80.60.80.60.80.5
Time in novel zone, NPP test0.40.50.80.3-0.5-0.70.80.90.60.80.60.80.5
Total zone transitions, NPP test1.62.33.01.5-1.7-1.71.61.41.51.31.51.21.5
Total locomotion distance, NPP test0.30.40.70.3-0.4-0.50.70.80.80.80.80.60.5
Locomotion velocity, NPP test0.20.20.40.2-0.3-0.40.50.60.60.60.60.40.4
Intraocular pressure1.31.92.5-1.31.41.5-1.5-1.5-1.1-1.4-1.6-1.0-1.4
Delta distance traveled before/after self-admin0.20.20.8-0.10.20.3-0.4-0.5-0.9-0.5-0.5-0.7-0.3
Delta ambulatory time before/after self-admin0.20.30.90.00.20.3-0.4-0.6-0.8-0.6-0.5-0.9-0.4
Parametrial fat weight0.41.05.0-2.21.71.2-0.20.4-0.00.6-0.20.2-0.7
Pavlov. Cond. lever latency0.20.30.8-0.70.70.6-0.5-0.4-0.4-0.3-0.5-0.2-0.9
Pavlov. Cond. magazine entry latency0.60.81.40.1-0.6-0.81.11.20.91.21.01.00.7
Pavlov. Cond. change in total contacts0.20.20.4-0.40.1-0.10.50.60.40.60.40.50.1
Pavlov. Cond. index score0.00.00.1-0.20.0-0.00.10.1-0.10.10.0-0.00.4
Pavlov. Cond. latency score0.10.10.30.0-0.2-0.30.40.40.20.30.30.20.5
Pavlov. Cond. lever contacts0.10.10.50.3-0.4-0.40.40.30.30.30.40.10.7
Pavlov. Cond. magazine entry number0.00.00.20.4-0.2-0.20.10.00.30.10.20.1-0.1
Pavlov. Cond. intertrial magazine entries0.80.91.2-0.60.91.0-1.1-1.0-1.0-1.0-1.0-0.9-0.9
Pavlov. Cond. lever-magazine prob. diff.0.00.00.1-0.2-0.0-0.10.20.20.00.20.10.00.4
Pavlov. Cond. response bias0.10.10.2-0.40.20.2-0.1-0.1-0.4-0.2-0.3-0.20.1
Pavlov. Cond. lever latency0.00.00.10.20.10.0-0.00.10.30.10.30.1-0.3
Pavlov. Cond. magazine entry latency3.64.36.62.3-2.6-2.52.21.91.91.71.91.82.0
Pavlov. Cond. change in total contacts0.71.01.50.5-1.0-1.11.21.21.01.10.91.20.9
Pavlov. Cond. index score1.01.32.01.0-1.4-1.41.31.11.01.00.91.11.2
Pavlov. Cond. latency score0.70.91.40.9-1.2-1.21.10.90.80.80.70.91.0
Pavlov. Cond. lever contacts0.00.00.2-0.0-0.2-0.20.20.1-0.20.0-0.20.10.4
Pavlov. Cond. magazine entry number4.04.97.8-2.52.82.7-2.3-1.9-2.1-1.8-2.0-1.9-2.1
Pavlov. Cond. intertrial magazine entries0.81.22.4-1.41.51.4-1.1-0.8-0.9-0.7-0.8-0.9-1.1
Pavlov. Cond. lever-magazine prob. diff.1.21.72.51.3-1.6-1.61.41.21.11.11.11.21.3
Pavlov. Cond. response bias1.01.42.01.1-1.4-1.41.31.11.01.00.91.11.2
Time in closed arm before self-admin0.20.20.5-0.50.30.00.50.70.50.70.5-0.0-0.2
Time in closed arm after self-admin0.10.10.1-0.20.30.3-0.3-0.30.2-0.2-0.20.0-0.2
Time in open arm before self-admin0.30.30.70.3-0.20.0-0.5-0.7-0.8-0.8-0.6-0.60.4
Time in open arm after self-admin0.30.30.80.8-0.9-0.80.60.40.00.30.40.10.6
Bone: periosteal estimation0.00.10.1-0.30.20.10.20.30.20.3-0.00.4-0.0
Bone: periosteal perimeter0.30.51.1-0.0-0.3-0.50.80.90.91.00.71.00.3
Bone: post-yield work6.910.216.11.2-2.1-2.83.63.93.74.03.73.61.7
Progressive ratio test 1 active lever presses0.10.10.6-0.10.30.3-0.2-0.20.4-0.00.00.5-0.8
Progressive ratio test 1 breakpoint0.10.10.5-0.10.20.2-0.2-0.30.4-0.1-0.00.5-0.7
Progressive ratio test 1 inactive lever presses0.10.10.60.10.10.1-0.1-0.10.50.10.20.8-0.7
Progressive ratio test 2 active lever presses0.30.41.2-1.11.00.7-0.20.10.20.40.00.6-0.9
Progressive ratio test 2 breakpoint0.30.41.1-1.11.00.7-0.20.10.10.3-0.00.4-0.9
Progressive ratio test 2 inactive lever presses1.21.96.6-2.62.31.6-0.60.1-0.30.5-0.40.9-1.6
Incentive Sensitization - Responses0.50.71.10.5-0.6-0.81.01.00.81.01.00.60.7
Incentive Sensitization - Breakpoint0.40.50.90.3-0.4-0.60.80.90.71.00.90.50.6
Sum of active levers in priming session hrs 5-63.63.35.0-0.91.41.7-2.1-2.2-2.2-2.2-2.0-1.8-1.1
Progressive ratio3.85.97.81.9-2.4-2.72.82.72.32.72.62.21.7
Food seeking constrained by brief footshock0.20.20.50.5-0.6-0.60.50.50.30.40.50.70.3
Seeking ratio, punishment vs. effort2.43.44.6-1.62.02.1-2.1-2.0-1.7-2.0-2.0-1.4-1.4
Retroperitoneal fat weight2.410.434.0-5.85.04.1-2.2-1.0-2.4-0.6-2.3-1.3-3.1
Reaction time number correct0.20.30.80.30.00.3-0.7-0.8-0.5-0.9-0.4-0.80.1
Reaction time mean minus median0.92.14.21.8-2.0-1.91.41.11.71.01.31.00.8
Reaction time mean minus median AUC0.30.82.31.5-1.5-1.20.70.40.90.30.60.30.4
Reaction time num false alarms0.81.11.9-0.40.50.8-1.2-1.2-1.2-1.3-1.3-1.4-0.6
Reaction time num false alarms AUC0.30.51.20.3-0.20.1-0.7-0.8-0.9-1.0-0.8-1.1-0.1
Reaction time trials correct on left0.20.30.80.30.00.3-0.7-0.8-0.5-0.9-0.4-0.80.1
Reaction time trials on left0.20.40.90.3-0.00.3-0.7-0.9-0.5-0.9-0.5-0.90.1
Reaction time mean0.20.40.70.2-0.6-0.70.80.90.50.80.60.30.6
Reaction time mean AUC0.30.40.90.2-0.5-0.70.80.90.60.90.70.40.5
Median of all reaction times0.30.40.9-0.1-0.3-0.50.80.90.40.90.60.40.7
Reaction time omissions0.81.13.31.8-1.7-1.40.70.40.90.30.80.01.0
Reaction time false alarm rate0.20.30.6-0.10.10.3-0.6-0.6-0.7-0.7-0.8-0.7-0.4
Reaction time premature initiation rate0.91.24.62.1-1.8-1.50.80.40.60.20.90.20.8
Reaction time premature initiations0.61.15.12.3-1.7-1.20.2-0.20.2-0.40.5-0.40.8
Std. dev. reaction times0.50.91.71.0-1.3-1.21.00.91.00.80.80.50.4
Reaction time trials completed0.20.40.90.3-0.00.3-0.7-0.9-0.5-0.9-0.5-0.90.1
Reaction time trials AUC0.10.30.70.3-0.00.2-0.6-0.8-0.4-0.8-0.4-0.80.2
Run reversals in cocaine runway, females1.71.72.11.4-1.4-1.41.31.21.31.21.41.01.4
Run reversals in cocaine runway, males0.70.71.1-0.10.40.6-0.9-1.0-1.1-1.0-0.9-1.0-0.5
Latency to leave start box in cocaine runway0.80.91.60.2-0.5-0.81.11.30.91.31.11.10.8
Latency to leave start box in cocaine runway, F0.80.91.40.4-0.6-0.81.01.20.91.11.00.91.1
Latency to leave start box in cocaine runway, M0.00.00.10.1-0.2-0.20.20.30.00.30.20.20.1
Std. dev. time between licks in bursts0.60.81.80.20.10.5-1.0-1.2-1.0-1.3-0.9-1.20.0
Total sessions with >9 infusions0.30.40.70.7-0.5-0.60.60.50.80.70.80.8-0.1
Short access day 1 total inactive lever presses0.50.61.8-1.41.21.0-0.5-0.2-0.3-0.0-0.30.4-1.0
Short access day 10 total inactive lever presses0.00.10.30.0-0.1-0.20.20.20.20.20.20.6-0.2
Short access day 1 total infusions0.20.30.8-0.60.70.40.00.30.20.50.20.9-0.9
Short access day 10 total infusions1.72.23.70.7-0.9-1.21.51.81.81.91.81.90.6
Short access total infusions0.70.92.00.5-0.5-0.70.91.01.21.21.11.40.1
Short access day 1 locomotion0.20.20.5-0.70.60.4-0.00.30.20.40.30.4-0.6
Short access day 10 total locomotion0.10.30.6-0.20.1-0.20.40.80.60.80.70.40.1
Short access total locomotion0.20.20.4-0.50.40.10.20.60.50.60.50.4-0.5
One hour access (0.3 mA shock)1.01.13.9-2.01.71.2-0.40.1-0.30.4-0.40.4-1.4
Compulsive drug intake0.40.51.91.4-0.9-0.4-0.3-0.8-0.3-0.8-0.4-0.1-0.5
One hour access (shock baseline)1.21.86.9-2.62.31.7-0.70.0-0.40.2-0.50.2-1.5
Social response proportion0.70.81.30.9-1.2-1.11.00.81.00.91.00.50.8
Social responses0.10.10.30.6-0.5-0.2-0.0-0.30.3-0.30.1-0.40.3
Social time0.20.30.90.9-0.8-0.70.50.20.70.20.50.20.5
Soleus weight2.98.615.6-3.93.93.6-2.8-2.2-2.5-1.9-2.7-1.9-2.9
Bone: stiffness2.44.04.81.7-2.0-2.22.22.12.12.01.92.11.6
Tibialis anterior weight1.24.217.84.2-2.7-1.4-0.7-1.8-0.3-2.3-0.7-1.21.9
Time to tail flick, vehicle, before self-admin1.61.72.71.0-1.3-1.51.61.71.01.41.40.71.3
Time to tail flick, vehicle, after self-admin2.73.65.01.9-2.0-2.01.91.72.21.71.92.21.3
Time to tail flick, test, before self-admin1.41.42.60.0-0.4-0.81.31.51.61.61.41.50.5
Time to tail flick, test, after self-admin0.20.20.9-0.20.20.2-0.2-0.3-0.2-0.4-0.3-1.00.4
Delta time to tail flick, vehicle, before/after SA1.11.12.91.1-1.0-0.90.70.51.50.70.91.70.7
Delta time to tail flick, test, before/after SA3.33.48.3-0.30.81.3-1.9-2.2-2.1-2.4-2.0-2.9-0.7
Tibia length0.51.42.5-0.20.60.9-1.3-1.5-1.4-1.6-1.6-1.3-0.5
Ambulatory time before self-admin0.50.81.40.4-0.7-0.91.01.10.81.00.91.20.7
Ambulatory time after self-admin0.20.30.7-0.40.1-0.20.70.80.20.80.50.60.2
Bone: tissue strength0.10.10.3-0.1-0.1-0.20.40.50.50.50.30.60.1
Total heroin consumption1.31.55.02.2-1.8-1.50.90.41.00.30.80.91.1
Bone: trabecular number2.94.96.81.6-2.2-2.42.62.51.92.42.31.91.9
Bone: trabecular spacing0.81.11.8-0.91.21.3-1.3-1.2-0.4-1.1-1.0-0.7-1.0
Bone: trabecular thickness0.91.22.40.2-0.7-1.01.41.60.71.51.21.00.7
Bone: trabecular tissue density4.77.012.1-3.53.53.2-2.6-2.1-2.2-1.8-2.6-1.6-2.6
Water consumed over 24 hours0.81.01.71.1-1.3-1.21.10.90.80.80.80.90.9
Number of responses in last shaping day0.00.00.10.3-0.00.1-0.2-0.30.3-0.20.10.3-0.2