Knop1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression Knop1 0.06 0.04 5.4e-04 0.02 0.03 0.03 0.03 1.6e-02 2.1e-03 1.9e-03 3.6e-03
2 PL gene expression Knop1 0.12 0.07 9.7e-10 0.06 0.08 0.07 0.08 2.2e-07 5.5e-09 1.5e-08 6.2e-09
3 NAcc gene expression Knop1 0.06 0.03 3.2e-12 0.08 0.08 0.06 0.08 1.2e-11 3.7e-12 4.3e-10 2.2e-12
4 Brain gene expression Knop1 0.04 0.03 7.5e-03 0.01 0.01 0 0.01 2.1e-02 4.3e-02 3.4e-01 9.0e-02
5 pVTA mRNA stability Knop1 0.05 0.03 1.4e-04 0.04 0.05 0.04 0.04 1.7e-04 1.0e-04 1.9e-04 1.5e-04
6 NAcc mRNA stability Knop1 0.07 0.05 9.7e-07 0.03 0.03 0.04 0.03 1.5e-05 2.4e-05 4.6e-07 1.0e-05
7 LHb gene expression Knop1 0.25 0.18 7.3e-03 0.03 0.01 0.07 0.05 5.4e-02 1.6e-01 1.2e-02 3.0e-02
8 PL mRNA stability Knop1 0.12 0.11 7.1e-03 0 0.03 0.04 0.02 1.5e-01 9.3e-04 7.9e-05 4.5e-03
9 Adipose mRNA stability Knop1 0.08 0.04 1.0e-08 0.07 0.06 0.06 0.06 2.1e-08 8.5e-07 5.7e-07 3.0e-07
10 IL mRNA stability Knop1 0.28 0.14 3.1e-03 0.08 0.11 0.1 0.07 4.8e-03 1.6e-03 2.3e-03 7.2e-03
11 Adipose alternative TSS NM_001399776.1 0.06 0.03 1.8e-05 0.04 0.04 0.03 0.03 3.4e-05 6.2e-05 1.1e-04 1.1e-04
12 Adipose alternative TSS NM_001399775.1 0.06 0.03 1.5e-05 0.04 0.04 0.04 0.03 3.1e-05 5.5e-05 7.3e-05 1.2e-04
13 Adipose alternative TSS XM_039087781.2 0.06 0.03 1.4e-05 0.04 0.04 0.04 0.04 2.7e-05 3.5e-05 4.6e-05 8.0e-05
14 Adipose alternative TSS XM_039087781.2 0.06 0.03 1.4e-05 0.04 0.04 0.04 0.04 2.6e-05 3.3e-05 5.2e-05 7.9e-05
15 Adipose isoform ratio XM_039087781.2 0.06 0.03 1.3e-05 0.04 0.04 0.03 0.03 4.7e-05 5.7e-05 2.0e-04 1.2e-04
16 Liver gene expression Knop1 0.05 0.03 2.2e-04 -0 0.01 0 0 3.8e-01 4.4e-02 2.9e-01 1.2e-01
17 Brain mRNA stability Knop1 0.07 0.04 2.1e-04 0.03 0.04 0.03 0.04 3.7e-04 5.4e-05 2.1e-03 2.1e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
Bone: apparent density0.61.23.3-1.71.81.6-1.61.7-1.5-1.40.1-0.10.20.30.3-0.3-0.3-0.31.00.8
Area under the delay curve0.20.32.4-0.00.0-0.50.3-0.6-0.9-0.5-1.5-0.50.6-0.4-0.40.40.40.40.10.4
BMI with tail2.17.216.5-3.43.34.1-4.04.0-1.4-1.83.62.2-1.22.32.3-2.3-2.3-2.30.90.2
BMI without tail1.89.425.5-4.64.74.9-4.95.1-2.8-2.42.61.7-0.71.71.7-1.7-1.7-1.71.91.1
Body weight1.35.816.2-4.03.93.8-3.74.0-2.6-2.21.01.1-0.81.11.1-1.1-1.1-1.11.50.7
Weight adjusted by age0.30.84.00.2-0.40.2-0.20.61.41.22.00.9-1.30.50.5-0.5-0.5-0.5-0.5-1.0
Bone surface0.71.42.6-1.51.41.6-1.61.3-1.2-1.40.40.9-0.81.21.2-1.2-1.2-1.2-0.1-0.3
Bone volume1.01.94.4-2.12.02.1-2.11.9-1.7-1.80.50.7-0.31.01.0-1.0-1.0-1.00.50.3
Breakpoint value in progressive ratio session0.71.32.61.1-1.2-1.51.4-0.91.21.6-0.5-1.0-0.1-1.4-1.41.41.41.4-0.1-0.3
Number of licking bursts1.03.010.53.0-3.1-2.52.6-3.21.71.1-0.9-0.20.5-0.1-0.10.10.10.1-1.6-0.8
Context. condit. distance diff. score0.40.40.90.5-0.5-0.70.7-0.30.90.90.1-0.8-0.0-0.8-0.80.80.80.80.0-0.1
Locomotion velocity, session 10.10.10.6-0.30.20.1-0.1-0.2-0.5-0.8-0.2-0.10.20.10.1-0.1-0.1-0.1-0.10.1
Locomotion distance, session 10.50.62.0-1.21.31.1-1.21.4-0.9-0.60.0-0.3-0.1-0.1-0.10.10.10.10.80.4
Locomotion velocity, session 20.10.10.70.0-0.0-0.20.2-0.4-0.6-0.5-0.8-0.10.5-0.1-0.10.10.10.10.00.3
Locomotion distance, session 21.11.53.4-1.81.81.8-1.81.6-1.8-1.6-0.20.4-0.40.80.8-0.8-0.8-0.80.40.2
Locomotion velocity, session 30.20.20.9-0.90.90.7-0.70.7-0.5-0.50.1-0.1-0.40.20.2-0.2-0.2-0.20.2-0.0
Locomotion distance, session 30.91.12.1-0.2-0.10.4-0.3-0.20.1-0.30.90.9-1.41.41.4-1.4-1.4-1.4-1.4-1.3
Stereotopy head waving bouts, day 30.70.81.50.6-0.4-0.80.8-0.40.30.7-1.0-1.00.7-1.2-1.21.21.21.20.60.6
Stereotopy head waving duration, day 30.50.71.40.10.1-0.40.30.1-0.10.6-1.0-0.80.7-1.2-1.21.21.21.20.90.8
Locomotion velocity, session 71.71.94.4-1.30.91.3-1.10.7-0.3-0.71.42.1-2.11.51.5-1.5-1.5-1.5-1.3-1.6
Locomotion distance, session 70.81.13.20.2-0.50.00.0-0.70.50.11.31.8-1.31.11.1-1.1-1.1-1.1-1.6-1.4
Stereotopy head waving bouts, day 70.40.41.4-0.70.80.4-0.30.7-0.8-0.1-1.2-1.10.2-0.5-0.50.50.50.50.80.5
Stereotopy head waving duration, day 70.81.03.6-1.71.71.5-1.41.9-1.1-0.60.0-0.2-0.50.30.3-0.3-0.3-0.30.80.3
Locomotion velocity, session 80.10.21.0-0.30.40.2-0.10.2-0.7-0.5-1.0-0.80.2-0.1-0.10.10.10.10.30.3
Locomotion distance, session 80.10.10.4-0.60.60.5-0.50.6-0.2-0.40.3-0.2-0.3-0.1-0.10.10.10.10.2-0.0
Degree of sensitization distance0.80.92.00.10.1-0.30.20.0-0.20.3-0.4-0.41.4-1.4-1.41.41.41.41.21.3
Degree of sensitization stereotypy0.80.92.7-1.61.61.5-1.31.4-1.3-1.0-0.4-0.1-0.50.50.5-0.5-0.5-0.50.40.1
Conditioned locomotion0.91.12.51.1-1.3-1.01.0-1.21.30.70.71.0-1.30.70.7-0.7-0.7-0.7-1.6-1.6
Cocaine response after cond. corrected0.10.10.40.6-0.6-0.50.4-0.60.1-0.2-0.3-0.10.2-0.0-0.00.00.00.0-0.2-0.0
Cocaine response after cond. not corrected0.10.10.3-0.20.10.2-0.40.1-0.3-0.50.20.4-0.30.50.5-0.5-0.5-0.5-0.3-0.3
Cocaine response before conditioning1.62.03.3-1.71.51.8-1.71.3-1.0-1.01.11.5-1.31.61.6-1.6-1.6-1.6-0.5-0.7
Saline control response0.30.40.90.2-0.1-0.60.4-0.00.20.40.1-0.80.7-1.0-1.01.01.01.00.70.6
Bone: connectivity density0.40.61.5-1.01.11.1-1.11.2-0.6-0.60.60.3-0.50.60.6-0.6-0.6-0.60.3-0.0
Bone: cortical apparent density0.40.72.11.3-1.3-1.21.2-1.50.30.4-1.0-0.60.7-0.5-0.50.50.50.5-0.40.0
Bone: cortical area1.93.17.6-2.72.52.8-2.72.2-2.3-2.30.61.2-0.41.11.1-1.1-1.1-1.10.50.4
Bone: cortical porosity0.40.41.7-1.01.00.9-0.81.3-0.10.10.70.4-0.80.30.3-0.3-0.3-0.30.3-0.2
Bone: cortical porosity0.20.21.0-0.70.70.3-0.31.00.30.60.40.0-0.7-0.2-0.20.20.20.20.4-0.2
Bone: cortical thickness1.11.86.2-2.11.91.9-1.81.2-2.5-2.2-0.50.50.80.20.2-0.2-0.2-0.20.91.1
Bone: cortical thickness1.01.25.0-1.31.31.0-0.90.3-2.2-2.0-1.1-0.11.4-0.2-0.20.20.20.21.01.4
Bone: cortical tissue density0.40.72.11.3-1.3-1.21.2-1.40.40.5-1.0-0.60.6-0.5-0.50.50.50.5-0.40.0
Condit. Reinf. active minus inactive responses0.30.30.60.3-0.2-0.50.40.00.70.80.2-0.70.1-0.7-0.70.70.70.70.30.2
Condit. Reinf. active-inactive response ratio0.20.20.80.2-0.1-0.30.20.30.90.80.5-0.3-0.5-0.3-0.30.30.30.30.0-0.3
Condit. Reinf. active responses0.20.30.50.2-0.2-0.40.3-0.00.60.60.6-0.50.5-0.7-0.70.70.70.70.50.5
Condit. Reinf. inactive responses0.10.10.6-0.00.00.1-0.00.1-0.00.00.7-0.10.8-0.3-0.30.30.30.30.50.7
Incentive salience index mean0.20.21.10.1-0.2-0.1-0.00.10.70.51.10.4-0.70.40.4-0.4-0.4-0.4-0.5-0.6
Condit. Reinf. lever presses0.60.92.70.5-0.7-0.20.1-0.21.10.61.61.1-1.21.01.0-1.0-1.0-1.0-1.1-1.3
Condit. Reinf. active minus inactive responses0.61.02.9-0.71.10.9-0.91.70.20.51.4-0.80.6-0.8-0.80.80.80.81.61.1
Condit. Reinf. active-inactive response ratio0.61.02.30.00.40.1-0.11.00.71.01.0-1.11.0-1.2-1.21.21.21.21.51.2
Condit. Reinf. active responses0.40.52.1-0.70.90.9-0.81.50.20.31.2-0.50.1-0.2-0.20.20.20.21.00.6
Condit. Reinf. inactive responses0.91.32.1-1.10.81.2-1.10.8-0.5-1.00.61.1-1.31.51.5-1.5-1.5-1.5-0.7-0.9
Condit. Reinf. lever presses0.60.93.9-1.31.51.7-1.52.0-0.2-0.31.1-0.2-0.30.20.2-0.2-0.2-0.21.00.4
Condit. Reinf. lever reinforcers received0.30.41.5-0.40.60.6-0.51.20.60.61.2-0.60.1-0.4-0.40.40.40.40.90.5
Conditioned reinforcement - actives0.20.63.1-0.70.90.2-0.10.2-1.4-1.1-1.8-0.40.9-0.4-0.40.40.40.40.80.9
Conditioned reinforcement - inactives0.20.41.30.9-0.6-0.80.9-1.1-0.1-0.3-0.9-0.61.2-0.2-0.20.20.20.20.10.6
Conditioned locomotion0.00.00.30.1-0.1-0.40.3-0.4-0.0-0.2-0.5-0.10.3-0.1-0.10.10.10.1-0.00.1
Patch foraging indifference point 0 sec0.71.93.8-1.11.40.4-0.81.4-1.1-0.7-1.1-1.71.2-1.6-1.61.61.61.61.91.7
Patch foraging indifference point AUC0.20.51.1-0.70.81.1-1.00.7-1.0-1.10.3-0.11.00.10.1-0.1-0.1-0.10.81.0
Delay disc. indifference point, 0s delay0.91.02.9-0.70.71.2-1.10.1-1.3-1.70.11.0-0.31.21.2-1.2-1.2-1.2-0.7-0.3
Delay disc. indifference point, 16s delay2.43.47.21.9-1.6-2.42.3-1.90.51.2-2.7-2.01.4-2.0-2.02.02.02.00.40.7
Delay disc. indifference point, 2s delay2.62.95.8-2.22.02.3-2.41.7-2.0-2.11.11.5-0.71.61.6-1.6-1.6-1.6-0.1-0.1
Delay disc. indifference point, 24s delay1.21.95.01.7-1.8-2.22.2-2.10.81.1-1.8-1.30.6-0.9-0.90.90.90.9-0.4-0.1
Delay disc. indifference point, 4s delay0.60.62.8-0.80.70.2-0.3-0.1-1.7-1.5-1.2-0.31.1-0.1-0.10.10.10.10.50.9
Delay disc. indifference point, 8s delay0.10.21.1-0.40.30.0-0.1-0.3-0.9-0.8-1.10.4-0.00.20.2-0.2-0.2-0.2-0.3-0.1
Indifference point function ln k0.10.20.8-0.70.60.3-0.40.5-0.6-0.90.10.5-0.10.10.1-0.1-0.1-0.10.20.1
Indifference point function log k0.10.20.8-0.70.60.3-0.40.5-0.6-0.90.10.5-0.10.10.1-0.1-0.1-0.10.20.1
Patch foraging total patch changes 0 sec0.82.34.8-1.21.50.5-0.81.6-1.1-0.7-1.0-1.81.3-1.8-1.81.81.81.82.21.8
Patch foraging total patch changes 12 sec0.10.10.5-0.20.40.4-0.50.7-0.1-0.10.2-0.60.2-0.3-0.30.30.30.30.50.4
Patch foraging total patch changes 18 sec0.30.61.8-0.10.3-0.0-0.20.1-0.5-0.4-0.7-1.31.2-0.9-0.90.90.90.90.91.1
Patch foraging total patch changes 24 sec0.31.12.3-1.21.40.9-0.91.2-1.1-0.5-0.7-1.11.0-0.9-0.90.90.90.91.51.4
Patch foraging total patch changes 6 sec2.94.99.2-0.20.8-0.40.20.5-1.2-0.5-2.2-3.03.0-2.8-2.82.82.82.82.93.0
Patch foraging time to switch 0 sec0.83.26.72.4-2.6-2.02.0-2.22.52.20.10.5-1.80.60.6-0.6-0.6-0.6-2.4-2.4
Patch foraging water rate 0 sec0.10.30.8-0.90.80.7-0.70.9-0.6-0.70.10.20.10.00.0-0.0-0.0-0.00.60.4
Patch foraging water rate 12 sec0.52.14.4-2.02.11.3-1.31.7-2.0-1.3-1.1-0.81.2-0.9-0.90.90.90.92.01.8
Patch foraging water rate 18 sec0.30.71.7-1.31.20.6-0.51.2-0.9-0.5-0.8-0.50.4-0.8-0.80.80.80.81.30.9
Patch foraging water rate 24 sec0.40.61.9-1.41.30.9-0.90.7-1.3-1.1-0.10.30.6-0.1-0.10.10.10.10.70.8
Patch foraging water rate 6 sec0.60.83.3-0.40.50.1-0.10.2-0.7-0.8-0.3-1.01.8-0.9-0.90.90.90.91.31.7
Seeking ratio, delayed vs. immediate footshock0.10.10.2-0.30.30.5-0.20.4-0.2-0.20.10.30.2-0.3-0.30.30.30.30.40.3
Distance traveled before self-admin0.20.41.5-1.00.60.7-0.40.2-0.9-1.2-0.30.60.70.30.3-0.3-0.3-0.30.40.6
Distance traveled after self-admin1.12.04.1-1.51.41.7-1.60.8-1.6-2.00.21.8-0.41.61.6-1.6-1.6-1.6-0.4-0.2
Extensor digitorum longus weight3.212.723.5-4.13.64.8-4.83.2-2.7-3.62.53.9-2.83.93.9-3.9-3.9-3.9-1.2-1.5
Bone: elastic displacement0.81.02.20.2-0.1-0.60.8-0.4-0.20.3-1.4-1.51.4-1.2-1.21.21.21.21.01.2
Bone: elastic work0.30.41.1-1.11.00.9-0.80.7-0.8-0.9-0.1-0.10.40.10.1-0.1-0.1-0.10.60.6
Bone: endosteal estimation1.12.64.2-1.51.42.0-2.01.8-0.2-0.92.01.5-1.81.91.9-1.9-1.9-1.9-0.6-1.1
Bone: endosteal perimeter1.02.54.3-0.90.71.5-1.51.00.1-0.72.11.7-1.92.12.1-2.1-2.1-2.1-1.2-1.5
Epididymis fat weight0.41.96.2-2.12.22.1-2.12.5-1.3-1.01.20.10.20.20.2-0.2-0.2-0.21.51.0
Delta time in closed arm before/after self-admin1.41.33.40.3-0.40.4-0.5-0.20.30.40.51.4-1.81.41.4-1.4-1.4-1.4-1.7-1.8
Delta time in open arm before/after self-admin0.70.92.3-1.11.41.3-1.51.5-0.9-1.01.2-0.10.40.20.2-0.2-0.2-0.21.00.9
Diff in mean of infusions in LGA sessions0.91.63.30.20.1-0.30.30.30.20.20.1-1.51.8-1.7-1.71.71.71.71.71.8
Delay discount exponential model param0.20.32.3-0.10.10.6-0.40.70.80.41.50.4-0.50.30.3-0.3-0.3-0.30.0-0.3
Extinction: sum of active levers before priming0.30.51.71.3-1.2-1.00.8-0.81.31.00.4-0.4-0.2-0.1-0.10.10.10.1-0.5-0.5
Active lever presses in extinction session 60.10.10.3-0.20.2-0.0-0.10.40.20.10.0-0.20.1-0.5-0.50.50.50.50.50.3
Bone: final force2.94.811.9-3.23.03.4-3.32.8-2.5-2.91.21.6-0.51.51.5-1.5-1.5-1.50.70.4
Bone: final moment2.54.110.4-3.12.93.2-3.12.8-2.4-2.70.91.2-0.21.11.1-1.1-1.1-1.11.00.7
Food consumed during 24 hour testing period0.71.43.1-1.21.31.8-1.71.2-0.8-1.51.51.1-0.21.21.2-1.2-1.2-1.20.10.2
Glucose0.10.20.8-0.20.2-0.10.2-0.1-0.3-0.3-0.9-0.30.6-0.6-0.60.60.60.60.50.5
Heart weight0.10.10.3-0.30.30.4-0.50.4-0.4-0.40.00.10.30.10.1-0.1-0.1-0.10.30.3
Delay discount hyperbolic model param0.10.21.30.3-0.20.2-0.10.30.90.61.10.2-0.30.10.1-0.1-0.1-0.1-0.0-0.2
Intermittent access intake day 1-15 change0.10.62.31.2-1.2-0.81.0-1.50.5-0.3-0.1-0.10.40.70.7-0.7-0.7-0.7-0.9-0.3
Intermittent access intake escalation0.10.62.51.1-1.1-0.91.1-1.60.3-0.4-0.6-0.30.60.40.4-0.4-0.4-0.4-0.7-0.0
Intermittent access intake escalation 20.40.73.11.2-1.2-0.91.1-1.70.1-0.7-0.90.00.50.60.6-0.6-0.6-0.6-1.0-0.3
Intermitt. access day 1 inactive lever presses0.00.31.51.2-1.0-0.70.6-1.10.50.30.3-0.10.50.20.2-0.2-0.2-0.2-0.5-0.0
Intermitt. access day 15 inactive lever presses0.10.40.8-0.20.30.6-0.50.3-0.3-0.70.40.5-0.40.90.9-0.9-0.9-0.9-0.4-0.3
Intermitt. access escalation Index0.10.21.4-0.30.30.5-0.60.80.2-0.21.2-0.20.30.00.0-0.0-0.0-0.00.60.5
Intermittent access day 1 total infusions0.20.51.6-1.01.20.9-0.91.3-0.1-0.31.1-0.6-0.2-0.1-0.10.10.10.10.70.3
Intermittent access day 15 total infusions0.00.10.40.10.0-0.10.1-0.20.1-0.40.3-0.60.40.10.1-0.1-0.1-0.10.10.3
Intermittent access terminal intake (last 3 days)0.10.10.3-0.40.40.3-0.30.3-0.0-0.60.5-0.50.40.10.1-0.1-0.1-0.10.40.4
Intermittent access total infusions0.60.72.2-1.41.51.1-1.11.3-0.8-1.10.6-0.10.20.10.1-0.1-0.1-0.10.80.7
Intermittent access day 1 locomotion0.20.41.0-0.80.90.6-0.60.9-0.1-0.30.8-1.00.4-0.4-0.40.40.40.40.90.7
Intermittent access day 15 total locomotion0.20.82.40.10.1-0.30.30.10.1-0.10.0-1.51.4-1.0-1.01.01.01.01.21.3
Intermittent access total locomotion0.60.72.0-0.80.90.5-0.51.1-0.1-0.20.9-1.10.9-0.7-0.70.70.70.71.41.2
Intermittent access standard deviation0.31.54.7-0.70.91.2-1.20.4-1.2-2.20.40.3-0.11.71.7-1.7-1.7-1.7-0.4-0.0
Left kidney weight0.76.014.0-3.73.53.7-3.63.3-2.6-3.21.61.6-0.61.71.7-1.7-1.7-1.70.90.5
Right kidney weight1.06.817.5-4.24.04.0-4.03.9-3.1-3.21.11.4-0.31.31.3-1.3-1.3-1.31.61.1
Cocaine induced anxiety0.10.41.50.7-1.0-0.40.4-0.61.00.61.20.50.10.50.5-0.5-0.5-0.5-0.5-0.3
Post-drug Anxiety0.60.61.90.4-0.4-0.70.7-0.40.20.2-0.3-0.81.4-1.0-1.01.01.01.00.81.1
Baseline Anxiety1.01.64.4-1.11.40.4-0.30.7-1.7-1.3-2.1-0.91.2-1.2-1.21.21.21.21.51.5
Tail length0.42.26.5-2.42.51.8-1.71.8-2.5-1.6-1.5-0.20.5-0.4-0.40.40.40.41.31.1
Length with tail0.31.46.8-1.61.50.5-0.50.8-1.9-0.8-2.6-0.60.1-1.1-1.11.11.11.10.90.6
Length without tail0.21.06.10.3-0.5-1.31.3-1.1-0.30.1-2.5-0.50.1-1.1-1.11.11.11.1-0.2-0.2
Times rat made contact with spout2.32.65.2-0.70.61.5-1.30.4-0.3-1.32.12.0-1.12.32.3-2.3-2.3-2.3-1.2-1.0
Lifetime Intake0.81.03.4-1.81.81.4-1.31.6-1.1-1.20.50.20.10.20.2-0.2-0.2-0.20.90.7
Liver weight, left0.30.52.41.0-0.8-0.80.7-0.01.31.60.0-0.5-0.6-0.4-0.40.40.40.4-0.1-0.5
Liver weight, right0.30.62.20.7-0.7-0.70.5-0.21.11.5-0.00.2-1.40.20.2-0.2-0.2-0.2-0.8-1.3
Locomotor activity0.00.10.40.2-0.00.0-0.10.30.20.6-0.1-0.7-0.3-0.1-0.10.10.10.10.0-0.2
Locomotor testing distance0.00.10.4-0.20.40.4-0.50.6-0.20.2-0.1-0.60.0-0.1-0.10.10.10.10.40.2
Locomotor testing rearing0.10.31.80.2-0.1-0.30.20.30.91.40.6-0.6-0.2-0.6-0.60.60.60.60.3-0.0
Locomotion in novel chamber0.60.82.3-1.21.00.7-0.71.5-0.10.30.7-0.40.5-0.8-0.80.80.80.81.51.0
Locomotion in novel chamber post-restriction0.51.42.70.3-0.1-0.70.50.40.00.6-1.2-1.51.6-1.5-1.51.51.51.51.71.5
Fecal boli incidents, locomotor time 10.41.03.90.8-1.0-0.61.1-0.42.01.91.30.4-1.30.20.2-0.2-0.2-0.2-0.9-1.3
Change in fecal boli incidents, locomotor task2.52.76.3-2.11.90.7-0.91.3-2.5-1.6-2.0-1.51.8-1.1-1.11.11.11.12.22.2
Time >=10cm from walls, locomotor time 10.40.51.2-0.80.71.1-0.70.5-0.7-1.00.00.7-0.20.90.9-0.9-0.9-0.9-0.1-0.1
Bouts of movement, locomotor time 11.72.16.12.1-2.3-2.02.1-1.72.51.90.9-1.00.6-0.9-0.90.90.90.9-0.3-0.1
Total resting periods, locomotor time 12.02.36.12.2-2.4-2.22.3-1.92.52.10.5-1.00.3-0.8-0.80.80.80.8-0.6-0.4
Rest time, locomotor task time 10.61.02.70.7-1.3-1.21.4-1.60.90.9-0.50.1-0.80.50.5-0.5-0.5-0.5-1.5-1.3
Distance moved, locomotor task time 10.41.12.8-1.21.41.1-1.51.7-1.0-1.00.2-0.40.8-0.5-0.50.50.50.51.51.3
Vertical activity count, locomotor time 10.21.64.2-1.31.71.9-2.01.5-1.8-2.00.30.21.20.30.3-0.3-0.3-0.31.21.5
Time >=10cm from walls, locomotor time 20.61.63.0-1.51.41.6-1.51.0-1.3-1.70.41.5-0.71.41.4-1.4-1.4-1.4-0.2-0.3
Bouts of movement, locomotor time 20.51.65.50.3-0.60.2-0.20.42.01.32.41.1-2.20.90.9-0.9-0.9-0.9-1.4-1.9
Total resting periods, locomotor time 20.41.44.8-0.0-0.30.4-0.50.61.61.02.11.1-2.20.90.9-0.9-0.9-0.9-1.3-1.9
Rest time, locomotor task time 20.10.21.3-0.90.50.10.00.2-0.8-0.3-1.1-0.40.2-0.3-0.30.30.30.30.40.3
Distance moved, locomotor task time 20.40.52.0-0.10.20.7-0.9-0.1-0.3-1.40.91.00.10.80.8-0.8-0.8-0.8-0.5-0.1
Vertical activity count, locomotor time 20.20.52.5-0.30.60.8-0.80.0-1.1-1.6-0.20.11.20.20.2-0.2-0.2-0.20.41.0
Light reinforcement 10.10.71.90.2-0.0-0.40.40.30.30.7-1.0-1.40.3-1.1-1.11.11.11.10.80.5
Light reinforcement 20.20.40.9-0.10.2-0.10.10.50.30.4-0.4-0.90.4-0.9-0.90.90.90.90.90.6
Bone: marrow area1.02.43.7-1.41.31.9-1.91.7-0.2-0.81.91.4-1.71.81.8-1.8-1.8-1.8-0.6-1.0
Bone: maximum diameter1.32.66.3-2.12.02.5-2.52.2-1.4-1.61.31.2-0.91.41.4-1.4-1.4-1.40.2-0.2
Bone: maximum force2.24.410.8-3.02.83.3-3.22.6-2.5-2.90.91.4-0.51.61.6-1.6-1.6-1.60.60.4
Bone: maximum moment1.93.69.1-2.92.73.0-2.92.5-2.3-2.60.71.0-0.21.11.1-1.1-1.1-1.10.90.6
Mean time between licks in bursts0.10.41.50.8-1.1-0.50.6-0.51.20.80.70.4-0.30.30.3-0.3-0.3-0.3-0.6-0.6
Mean num. licks in bursts1.64.310.3-3.23.23.1-3.23.1-1.9-1.91.91.2-0.91.31.3-1.3-1.3-1.30.90.3
Cd content in liver3.53.99.20.10.2-1.01.00.60.21.6-1.9-3.01.7-2.7-2.72.72.72.72.31.9
Co content in liver1.31.54.3-0.70.80.2-0.2-0.0-1.8-1.3-1.6-1.12.1-1.1-1.11.11.11.11.41.9
Cu content in liver0.91.02.3-1.51.41.2-1.11.3-1.5-1.0-0.3-0.30.9-0.5-0.50.50.50.51.41.3
Fe content in liver0.70.82.8-0.20.0-0.30.4-0.3-0.6-0.6-0.6-0.81.7-1.1-1.11.11.11.11.11.4
K content in liver0.20.10.8-0.40.40.5-0.50.70.0-0.30.90.10.2-0.0-0.00.00.00.00.50.4
Mg content in liver0.20.20.7-0.1-0.10.1-0.20.40.70.50.80.6-0.80.30.3-0.3-0.3-0.3-0.3-0.6
Mn content in liver0.40.51.2-0.40.30.6-0.70.50.1-0.11.10.9-0.70.80.8-0.8-0.8-0.8-0.4-0.5
Na content in liver4.24.89.9-1.21.12.3-2.21.50.0-1.23.23.0-2.22.72.7-2.7-2.7-2.7-1.3-1.7
Rb content in liver6.06.912.9-0.40.3-1.31.30.1-1.00.7-3.0-2.93.2-3.6-3.63.63.63.63.23.2
Se content in liver0.30.41.2-0.2-0.00.5-0.40.00.0-0.61.01.1-0.30.80.8-0.8-0.8-0.8-0.4-0.3
Sr content in liver0.60.51.6-0.20.50.9-0.90.70.1-0.21.20.4-0.70.80.8-0.8-0.8-0.8-0.3-0.5
Zn content in liver0.91.13.1-1.21.11.5-1.51.70.10.01.60.5-1.10.80.8-0.8-0.8-0.80.1-0.5
Bone: minimum diameter1.42.75.2-1.91.72.3-2.21.8-0.8-1.21.71.5-1.61.81.8-1.8-1.8-1.8-0.5-0.9
Time in familiar zone, hab. session 11.01.13.40.3-0.2-0.50.5-0.5-0.4-0.2-1.0-1.31.8-1.2-1.21.21.21.21.11.5
Time in novel zone, hab. session 11.01.15.2-0.90.60.5-0.60.6-0.00.20.11.0-2.31.11.1-1.1-1.1-1.1-1.2-1.7
Total zone transitions, hab. session 11.82.66.5-2.52.52.2-2.22.1-2.5-2.4-0.4-0.00.60.30.3-0.3-0.3-0.31.41.3
Total locomotion distance, hab. session 13.44.813.4-3.53.73.2-3.33.4-3.0-2.60.1-0.30.50.30.3-0.3-0.3-0.32.11.7
Locomotion velocity, hab. session 12.63.810.2-2.93.22.9-3.03.2-2.5-2.00.1-0.40.60.10.1-0.1-0.1-0.12.11.7
Time in familiar zone, hab. session 20.20.20.6-0.70.60.7-0.70.6-0.5-0.60.30.00.30.30.3-0.3-0.3-0.30.40.5
Time in novel zone, hab. session 20.10.10.20.2-0.1-0.30.30.00.20.4-0.1-0.3-0.1-0.4-0.40.40.40.40.1-0.0
Total zone transitions, hab. session 21.62.05.5-2.32.32.0-1.92.1-2.1-1.8-0.5-0.40.40.00.0-0.0-0.0-0.01.41.1
Total locomotion distance, hab. session 22.12.87.5-2.62.72.4-2.42.3-2.5-2.2-0.2-0.20.60.20.2-0.2-0.2-0.21.51.4
Locomotion velocity, hab. session 22.33.08.0-2.72.82.6-2.62.5-2.5-2.30.1-0.00.30.50.5-0.5-0.5-0.51.41.2
Novel to familiar place preference ratio0.40.51.41.2-1.0-0.90.8-1.10.40.2-0.3-0.61.0-0.5-0.50.50.50.50.00.5
Novelty place preference0.40.51.51.1-1.0-0.90.9-1.20.20.0-0.4-0.51.1-0.4-0.40.40.40.4-0.10.5
Time in novel zone, NPP test0.40.51.31.0-0.9-0.90.8-1.00.20.1-0.5-0.91.2-0.6-0.60.60.60.60.20.7
Total zone transitions, NPP test0.91.43.7-1.91.91.8-1.71.7-1.8-1.5-0.10.10.10.40.4-0.4-0.4-0.40.90.7
Total locomotion distance, NPP test1.11.53.8-1.81.91.9-1.91.6-1.8-1.70.4-0.00.60.40.4-0.4-0.4-0.41.01.1
Locomotion velocity, NPP test0.91.33.1-1.61.81.7-1.81.4-1.7-1.60.50.30.50.40.4-0.4-0.4-0.40.90.9
Intraocular pressure0.10.20.8-0.30.40.3-0.50.4-0.30.20.00.7-0.90.50.5-0.5-0.5-0.5-0.4-0.6
Delta distance traveled before/after self-admin0.40.51.3-0.50.70.6-0.90.7-0.3-0.30.10.8-1.10.70.7-0.7-0.7-0.7-0.5-0.8
Delta ambulatory time before/after self-admin0.50.91.4-0.70.90.9-1.20.7-0.6-0.90.71.2-1.21.11.1-1.1-1.1-1.1-0.7-0.8
Parametrial fat weight2.35.514.3-3.53.62.7-2.53.8-2.2-2.20.6-0.41.4-1.3-1.31.31.31.33.42.7
Pavlov. Cond. lever latency2.63.37.9-0.60.9-0.10.3-0.3-2.0-1.4-2.8-2.12.8-1.9-1.91.91.91.92.02.6
Pavlov. Cond. magazine entry latency3.74.816.1-0.80.51.6-1.71.81.30.84.02.9-3.12.32.3-2.3-2.3-2.3-1.5-2.3
Pavlov. Cond. change in total contacts4.95.210.90.3-0.80.5-0.60.01.81.23.23.1-3.32.62.6-2.6-2.6-2.6-2.8-3.2
Pavlov. Cond. index score3.34.211.00.1-0.40.7-0.80.91.81.43.32.6-3.22.22.2-2.2-2.2-2.2-2.0-2.7
Pavlov. Cond. latency score2.73.59.90.0-0.30.7-0.80.91.71.23.12.4-2.92.02.0-2.0-2.0-2.0-1.7-2.4
Pavlov. Cond. lever contacts3.34.09.9-0.1-0.20.8-0.91.01.61.13.12.5-3.12.32.3-2.3-2.3-2.3-1.9-2.6
Pavlov. Cond. magazine entry number3.44.311.40.00.2-0.81.0-0.8-1.6-1.1-3.4-2.93.1-2.3-2.32.32.32.32.12.7
Pavlov. Cond. intertrial magazine entries2.32.75.70.3-0.1-0.91.0-0.5-0.6-0.0-1.9-2.32.4-2.1-2.12.12.12.11.82.1
Pavlov. Cond. lever-magazine prob. diff.3.84.713.7-0.0-0.30.9-1.01.11.91.43.72.7-3.32.42.4-2.4-2.4-2.4-2.0-2.8
Pavlov. Cond. response bias4.55.713.30.0-0.40.8-0.90.71.81.23.53.1-3.62.72.7-2.7-2.7-2.7-2.5-3.2
Pavlov. Cond. lever latency0.50.72.71.3-1.4-1.31.2-1.60.40.5-0.8-0.10.2-0.3-0.30.30.30.3-0.8-0.3
Pavlov. Cond. magazine entry latency0.91.22.91.5-1.5-1.21.2-1.21.71.30.90.4-1.00.50.5-0.5-0.5-0.5-1.4-1.3
Pavlov. Cond. change in total contacts0.51.33.3-0.40.70.1-0.01.0-0.10.3-0.1-1.71.2-1.5-1.51.51.51.51.81.5
Pavlov. Cond. index score0.10.10.70.1-0.00.10.10.30.70.50.8-0.2-0.20.00.0-0.0-0.0-0.00.1-0.1
Pavlov. Cond. latency score0.10.10.60.1-0.10.10.00.30.60.40.80.0-0.40.30.3-0.3-0.3-0.3-0.1-0.3
Pavlov. Cond. lever contacts0.40.62.5-1.11.21.3-1.11.6-0.2-0.30.80.2-0.40.40.4-0.4-0.4-0.40.60.2
Pavlov. Cond. magazine entry number1.01.33.1-1.81.71.7-1.71.4-1.7-1.6-0.10.6-0.10.60.6-0.6-0.6-0.60.50.4
Pavlov. Cond. intertrial magazine entries0.81.74.9-1.91.92.0-2.12.2-1.1-1.10.80.9-0.80.90.9-0.9-0.9-0.90.50.0
Pavlov. Cond. lever-magazine prob. diff.0.10.20.80.4-0.3-0.20.30.10.90.70.8-0.1-0.40.10.1-0.1-0.1-0.1-0.1-0.3
Pavlov. Cond. response bias0.10.21.4-0.20.30.3-0.20.70.70.51.2-0.1-0.2-0.0-0.00.00.00.00.40.1
Time in closed arm before self-admin0.10.10.3-0.40.30.4-0.20.3-0.2-0.50.4-0.20.30.20.2-0.2-0.2-0.20.40.4
Time in closed arm after self-admin0.30.42.80.1-0.1-0.30.3-0.4-0.6-0.2-1.7-0.70.6-0.6-0.60.60.60.60.30.5
Time in open arm before self-admin0.60.71.71.3-1.2-1.31.2-1.20.91.1-0.8-0.0-0.1-0.5-0.50.50.50.5-0.6-0.5
Time in open arm after self-admin1.71.93.5-0.60.71.3-1.50.9-0.4-1.11.91.4-0.91.91.9-1.9-1.9-1.9-0.7-0.7
Bone: periosteal estimation1.94.610.0-2.72.53.2-3.12.6-1.6-2.11.81.8-1.52.12.1-2.1-2.1-2.1-0.2-0.6
Bone: periosteal perimeter1.02.04.5-1.71.62.1-2.01.9-0.6-1.01.61.1-1.31.41.4-1.4-1.4-1.4-0.1-0.6
Bone: post-yield work1.01.77.2-2.12.22.0-2.12.7-0.8-0.71.1-0.0-0.60.30.3-0.3-0.3-0.31.20.4
Progressive ratio test 1 active lever presses0.20.42.7-0.80.40.6-0.50.80.60.31.7-0.0-0.50.30.3-0.3-0.3-0.30.1-0.3
Progressive ratio test 1 breakpoint0.20.32.5-0.70.40.5-0.50.70.70.41.6-0.0-0.60.30.3-0.3-0.3-0.3-0.0-0.3
Progressive ratio test 1 inactive lever presses0.20.64.80.3-0.40.1-0.10.11.40.92.2-0.3-0.40.40.4-0.4-0.4-0.4-0.4-0.5
Progressive ratio test 2 active lever presses0.10.20.7-0.40.1-0.00.10.20.70.90.70.3-0.6-0.2-0.20.20.20.2-0.1-0.4
Progressive ratio test 2 breakpoint0.10.20.9-0.40.1-0.10.10.20.70.90.60.2-0.5-0.3-0.30.30.30.3-0.0-0.3
Progressive ratio test 2 inactive lever presses0.10.21.2-0.50.50.5-0.50.60.20.31.10.4-0.30.20.2-0.2-0.2-0.20.1-0.1
Incentive Sensitization - Responses0.10.20.9-0.2-0.2-0.30.2-0.10.50.90.31.0-0.9-0.0-0.00.00.00.0-0.6-0.8
Incentive Sensitization - Breakpoint0.10.20.8-0.3-0.0-0.20.20.00.40.80.40.9-0.8-0.1-0.10.10.10.1-0.4-0.6
Sum of active levers in priming session hrs 5-61.31.34.51.4-1.2-1.31.0-0.32.12.10.7-0.4-0.6-0.9-0.90.90.90.9-0.2-0.6
Progressive ratio0.30.92.4-0.50.80.2-0.30.7-1.0-0.1-1.5-0.80.9-1.1-1.11.11.11.11.31.2
Food seeking constrained by brief footshock0.60.71.31.1-0.9-1.11.0-1.00.60.6-0.0-1.10.9-0.9-0.90.90.90.90.20.4
Seeking ratio, punishment vs. effort0.51.14.40.2-0.50.00.1-0.41.00.12.11.0-1.21.11.1-1.1-1.1-1.1-1.3-1.3
Retroperitoneal fat weight1.46.117.5-3.33.62.4-2.34.2-1.8-0.50.3-1.11.2-2.1-2.12.12.12.13.92.8
Reaction time number correct0.20.72.11.0-0.8-1.01.1-0.61.21.5-0.1-1.0-0.2-0.6-0.60.60.60.6-0.2-0.4
Reaction time mean minus median0.00.10.4-0.30.20.4-0.40.4-0.2-0.70.5-0.30.50.20.2-0.2-0.2-0.20.40.5
Reaction time mean minus median AUC0.10.62.00.10.1-0.10.30.30.20.0-0.2-1.41.1-0.8-0.80.80.80.81.11.1
Reaction time num false alarms0.30.62.51.4-1.3-1.00.8-1.60.2-0.1-0.5-0.00.40.30.3-0.3-0.3-0.3-0.9-0.3
Reaction time num false alarms AUC0.20.51.71.3-1.2-0.90.7-1.30.40.2-0.40.2-0.10.30.3-0.3-0.3-0.3-1.0-0.6
Reaction time trials correct on left0.20.72.11.0-0.8-1.01.1-0.61.21.5-0.1-1.0-0.2-0.6-0.60.60.60.6-0.2-0.4
Reaction time trials on left0.20.72.21.0-0.8-1.11.2-0.61.31.5-0.0-1.0-0.3-0.6-0.60.60.60.6-0.2-0.4
Reaction time mean0.10.10.5-0.50.50.4-0.50.7-0.3-0.20.20.10.2-0.0-0.00.00.00.00.60.4
Reaction time mean AUC0.00.00.2-0.20.10.1-0.20.40.10.10.20.2-0.1-0.0-0.00.00.00.00.20.1
Median of all reaction times0.10.10.6-0.60.50.4-0.50.8-0.20.00.20.3-0.1-0.0-0.00.00.00.00.40.2
Reaction time omissions0.20.31.30.5-0.6-0.60.60.01.11.10.2-0.0-0.8-0.1-0.10.10.10.1-0.3-0.7
Reaction time false alarm rate0.30.51.00.7-0.8-0.30.1-1.0-0.3-0.7-0.30.8-0.00.80.8-0.8-0.8-0.8-1.0-0.5
Reaction time premature initiation rate1.21.82.8-1.21.11.3-1.50.7-0.9-1.31.41.5-1.11.71.7-1.7-1.7-1.7-0.8-0.8
Reaction time premature initiations0.30.91.8-0.50.40.5-0.70.1-0.1-0.31.20.9-1.31.31.3-1.3-1.3-1.3-1.1-1.1
Std. dev. reaction times0.10.20.7-0.60.60.5-0.50.7-0.5-0.5-0.2-0.40.5-0.2-0.20.20.20.20.80.7
Reaction time trials completed0.20.72.21.0-0.8-1.11.2-0.61.31.5-0.0-1.0-0.3-0.6-0.60.60.60.6-0.2-0.4
Reaction time trials AUC0.10.51.70.8-0.6-0.80.9-0.41.11.30.0-0.9-0.2-0.6-0.60.60.60.6-0.1-0.3
Run reversals in cocaine runway, females3.13.56.5-2.02.02.4-2.31.4-1.9-2.51.31.8-0.92.12.1-2.1-2.1-2.1-0.5-0.4
Run reversals in cocaine runway, males0.30.31.10.7-0.8-0.80.8-1.00.10.1-1.0-0.90.3-0.2-0.20.20.20.2-0.4-0.1
Latency to leave start box in cocaine runway1.01.43.1-0.40.6-0.10.30.5-0.30.2-1.3-1.81.3-1.5-1.51.51.51.51.61.4
Latency to leave start box in cocaine runway, F0.20.30.80.2-0.1-0.40.60.10.60.8-0.4-0.9-0.1-0.7-0.70.70.70.70.30.0
Latency to leave start box in cocaine runway, M2.01.94.1-0.91.00.2-0.20.7-1.1-0.4-1.5-1.51.9-1.6-1.61.61.61.62.02.0
Std. dev. time between licks in bursts0.40.74.80.5-0.40.2-0.20.51.30.82.20.5-0.60.70.7-0.7-0.7-0.7-0.3-0.5
Total sessions with >9 infusions2.73.411.2-3.33.12.8-2.73.0-2.0-1.70.41.0-0.80.80.8-0.8-0.8-0.81.00.4
Short access day 1 total inactive lever presses0.10.30.7-0.80.80.6-0.70.6-0.7-0.3-0.40.2-0.50.40.4-0.4-0.4-0.4-0.1-0.2
Short access day 10 total inactive lever presses0.21.13.51.7-1.7-1.51.5-1.91.30.9-0.2-0.0-0.20.10.1-0.1-0.1-0.1-1.2-0.8
Short access day 1 total infusions0.61.23.7-1.91.81.4-1.41.3-1.7-1.2-1.10.8-0.70.60.6-0.6-0.6-0.60.2-0.1
Short access day 10 total infusions0.91.54.5-2.11.91.8-1.72.0-0.9-1.00.80.5-1.00.80.8-0.8-0.8-0.80.4-0.1
Short access total infusions1.72.37.9-2.82.62.2-2.22.4-1.8-1.60.40.6-0.50.60.6-0.6-0.6-0.60.90.4
Short access day 1 locomotion0.40.72.2-1.31.10.6-0.60.5-1.4-1.4-1.50.50.10.30.3-0.3-0.3-0.30.20.3
Short access day 10 total locomotion0.52.25.1-1.91.52.1-2.12.0-0.4-0.82.30.6-0.91.41.4-1.4-1.4-1.40.1-0.3
Short access total locomotion1.72.68.0-2.82.82.2-2.22.7-2.0-1.6-0.2-0.30.40.00.0-0.0-0.0-0.01.71.3
One hour access (0.3 mA shock)0.30.32.0-0.30.00.2-0.10.60.90.71.4-0.60.1-0.4-0.40.40.40.40.60.3
Compulsive drug intake0.20.32.30.3-0.2-0.1-0.10.30.51.50.10.1-0.3-0.6-0.60.60.60.60.2-0.1
One hour access (shock baseline)0.10.21.20.1-0.1-0.20.3-0.10.4-0.30.6-1.10.8-0.3-0.30.30.30.30.50.7
Social response proportion0.50.72.70.10.1-0.30.30.50.50.70.0-1.60.5-1.1-1.11.11.11.11.00.7
Social responses0.60.82.11.2-1.0-1.01.0-0.41.41.3-0.1-1.50.1-0.8-0.80.80.80.80.1-0.1
Social time0.71.13.30.9-0.7-1.21.1-0.70.50.9-1.1-1.80.6-1.3-1.31.31.31.30.40.4
Soleus weight1.64.711.3-3.43.43.2-3.22.8-3.3-3.20.10.60.50.90.9-0.9-0.9-0.91.61.5
Bone: stiffness1.83.39.1-2.42.22.7-2.61.7-2.5-3.00.71.4-0.11.41.4-1.4-1.4-1.40.30.4
Tibialis anterior weight3.913.431.6-5.45.25.6-5.64.6-4.2-4.51.92.6-1.02.72.7-2.7-2.7-2.71.10.6
Time to tail flick, vehicle, before self-admin0.10.10.3-0.30.30.5-0.60.3-0.3-0.20.5-0.10.30.10.1-0.1-0.1-0.10.20.3
Time to tail flick, vehicle, after self-admin1.02.14.62.0-1.9-2.02.1-1.62.12.1-0.1-1.2-0.3-1.0-1.01.01.01.0-0.7-0.8
Time to tail flick, test, before self-admin0.40.51.10.4-0.50.2-0.0-0.40.1-0.00.20.3-0.41.11.1-1.1-1.1-1.1-0.9-0.7
Time to tail flick, test, after self-admin2.72.88.41.4-1.6-0.50.5-1.11.90.42.91.5-1.51.81.8-1.8-1.8-1.8-2.2-2.0
Delta time to tail flick, vehicle, before/after SA0.30.30.60.6-0.4-0.80.7-0.20.70.7-0.1-0.6-0.2-0.7-0.70.70.70.70.1-0.1
Delta time to tail flick, test, before/after SA0.30.42.8-0.0-0.00.2-0.30.20.6-0.21.71.0-0.60.60.6-0.6-0.6-0.6-0.4-0.5
Tibia length0.30.81.9-0.40.60.2-0.30.3-1.0-0.9-1.1-1.41.2-0.8-0.80.80.80.81.11.2
Ambulatory time before self-admin0.20.51.7-0.90.50.30.0-0.2-1.1-1.3-1.10.21.3-0.2-0.20.20.20.20.71.1
Ambulatory time after self-admin1.32.04.9-1.71.51.7-1.50.7-1.9-2.2-0.12.0-0.31.51.5-1.5-1.5-1.5-0.3-0.0
Bone: tissue strength0.20.20.3-0.30.10.4-0.3-0.1-0.2-0.50.30.5-0.20.60.6-0.6-0.6-0.6-0.3-0.2
Total heroin consumption0.70.82.80.5-0.5-0.80.8-0.01.31.7-0.3-0.8-0.3-1.2-1.21.21.21.20.3-0.2
Bone: trabecular number0.40.81.8-1.31.41.2-1.31.1-1.2-1.30.40.30.20.50.5-0.5-0.5-0.50.60.5
Bone: trabecular spacing0.91.34.51.6-1.6-1.21.3-0.92.12.00.80.3-1.10.00.0-0.0-0.0-0.0-1.0-1.3
Bone: trabecular thickness3.24.58.9-2.73.02.0-2.02.5-2.9-2.1-1.1-1.42.1-1.3-1.31.31.31.33.02.8
Bone: trabecular tissue density0.10.10.40.00.00.1-0.1-0.1-0.5-0.6-0.6-0.30.7-0.2-0.20.20.20.20.30.5
Water consumed over 24 hours1.12.25.51.1-1.4-0.60.7-1.80.7-0.20.61.6-1.21.81.8-1.8-1.8-1.8-2.4-1.8
Number of responses in last shaping day0.20.30.8-0.50.40.4-0.40.1-0.4-0.1-0.90.4-0.90.60.6-0.6-0.6-0.6-0.6-0.7