Hub : Genes

Knop1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression Knop1 0.06 0.04 5.4e-04 0.02 0.03 0.03 0.03 1.6e-02 2.1e-03 1.9e-03 3.0e-03
2 PL gene expression Knop1 0.12 0.07 9.7e-10 0.06 0.08 0.07 0.08 2.2e-07 5.5e-09 1.5e-08 6.6e-09
3 NAcc gene expression Knop1 0.06 0.03 3.2e-12 0.08 0.08 0.06 0.08 1.2e-11 3.7e-12 4.7e-10 2.2e-12
4 Brain gene expression Knop1 0.04 0.03 7.5e-03 0.01 0.01 0 0 2.1e-02 4.3e-02 3.5e-01 9.9e-02
5 pVTA mRNA stability Knop1 0.05 0.03 1.4e-04 0.04 0.05 0.04 0.04 1.7e-04 1.0e-04 1.9e-04 1.5e-04
6 NAcc mRNA stability Knop1 0.07 0.05 9.7e-07 0.03 0.03 0.04 0.03 1.5e-05 2.4e-05 4.6e-07 9.3e-06
7 PL mRNA stability Knop1 0.12 0.11 7.1e-03 0 0.03 0.04 0.02 1.5e-01 9.3e-04 8.6e-05 4.8e-03
8 LHb gene expression Knop1 0.25 0.18 7.3e-03 0.03 0.01 0.07 0.05 5.4e-02 1.6e-01 1.2e-02 3.0e-02
9 Adipose mRNA stability Knop1 0.08 0.04 1.0e-08 0.07 0.06 0.06 0.06 2.1e-08 8.5e-07 5.7e-07 3.1e-07
10 IL mRNA stability Knop1 0.28 0.14 3.1e-03 0.08 0.11 0.1 0.07 4.8e-03 1.6e-03 2.3e-03 7.3e-03
11 Adipose alternative TSS NM_001399776.1 0.06 0.03 1.8e-05 0.04 0.04 0.03 0.03 3.4e-05 6.2e-05 1.1e-04 1.2e-04
12 Adipose alternative TSS XM_039087781.2 0.06 0.03 1.4e-05 0.04 0.04 0.04 0.04 2.6e-05 3.3e-05 5.2e-05 7.9e-05
13 Adipose alternative TSS XM_039087781.2 0.06 0.03 1.4e-05 0.04 0.04 0.04 0.04 2.7e-05 3.5e-05 4.6e-05 8.2e-05
14 Adipose isoform ratio XM_039087781.2 0.06 0.03 1.3e-05 0.04 0.04 0.03 0.03 4.7e-05 5.7e-05 2.0e-04 1.2e-04
15 Adipose alternative TSS NM_001399775.1 0.06 0.03 1.5e-05 0.04 0.04 0.04 0.03 3.1e-05 5.5e-05 7.3e-05 1.1e-04
16 Liver gene expression Knop1 0.05 0.03 2.2e-04 -0 0.01 0 0 3.8e-01 4.4e-02 2.9e-01 1.2e-01
17 Brain mRNA stability Knop1 0.07 0.04 2.1e-04 0.03 0.04 0.02 0.04 3.7e-04 5.4e-05 2.2e-03 1.9e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
Bone: apparent density0.71.23.31.71.81.61.61.71.5-0.21.40.10.2-0.30.30.30.3-0.31.00.8
Area under the delay curve0.30.32.40.00.0-0.5-0.3-0.60.91.50.50.50.60.4-0.4-0.4-0.40.40.10.4
BMI with tail2.17.216.53.43.34.14.04.01.4-3.61.8-2.2-1.2-2.32.32.32.3-2.30.90.2
BMI without tail3.19.425.54.64.74.94.95.12.8-2.72.4-1.7-0.7-1.71.71.71.7-1.71.91.1
Body weight1.35.816.24.03.93.83.74.02.6-1.12.2-1.1-0.8-1.11.11.11.1-1.11.50.7
Weight adjusted by age0.50.84.1-0.2-0.40.20.20.6-1.4-2.0-1.2-0.9-1.3-0.50.50.50.5-0.5-0.5-1.0
Bone surface0.71.42.61.51.41.61.61.31.2-0.41.4-0.9-0.8-1.21.21.21.2-1.2-0.1-0.3
Bone volume1.11.94.42.12.02.12.11.91.7-0.51.8-0.7-0.3-1.01.01.01.0-1.00.50.3
Breakpoint value in progressive ratio session1.11.32.6-1.1-1.2-1.5-1.4-0.9-1.20.5-1.61.0-0.11.4-1.4-1.4-1.41.4-0.1-0.3
Number of licking bursts1.93.010.5-3.0-3.1-2.5-2.6-3.2-1.71.0-1.10.20.50.1-0.1-0.1-0.10.1-1.6-0.8
Context. condit. distance diff. score0.40.40.9-0.5-0.5-0.7-0.7-0.3-0.9-0.1-0.90.8-0.00.8-0.8-0.8-0.80.80.0-0.1
Locomotion velocity, session 10.10.10.60.30.20.10.1-0.20.50.20.80.10.2-0.10.10.10.1-0.1-0.10.1
Locomotion distance, session 10.50.62.01.21.31.11.21.40.9-0.10.60.3-0.10.1-0.1-0.1-0.10.10.80.4
Locomotion velocity, session 20.10.10.7-0.0-0.0-0.2-0.2-0.40.60.80.50.10.50.1-0.1-0.1-0.10.10.00.3
Locomotion distance, session 21.11.53.41.81.81.81.81.61.80.11.6-0.4-0.4-0.80.80.80.8-0.80.40.2
Locomotion velocity, session 30.20.20.90.90.90.70.70.70.5-0.20.50.1-0.4-0.20.20.20.2-0.20.2-0.0
Locomotion distance, session 31.01.12.10.2-0.10.40.3-0.2-0.1-0.90.3-0.9-1.4-1.41.41.41.4-1.4-1.4-1.3
Stereotopy head waving bouts, day 30.70.81.5-0.6-0.4-0.8-0.8-0.4-0.31.0-0.71.00.71.2-1.2-1.2-1.21.20.60.6
Stereotopy head waving duration, day 30.60.71.4-0.10.1-0.4-0.30.10.11.0-0.60.80.71.2-1.2-1.2-1.21.20.90.8
Locomotion velocity, session 71.71.94.41.30.91.31.10.70.3-1.40.7-2.1-2.1-1.51.51.51.5-1.5-1.3-1.6
Locomotion distance, session 70.81.13.2-0.2-0.50.0-0.0-0.7-0.5-1.3-0.1-1.8-1.3-1.11.11.11.1-1.1-1.6-1.4
Stereotopy head waving bouts, day 70.40.41.40.70.80.40.30.70.81.20.11.10.20.5-0.5-0.5-0.50.50.80.5
Stereotopy head waving duration, day 70.81.03.61.71.71.51.41.91.1-0.10.60.2-0.5-0.30.30.30.3-0.30.80.3
Locomotion velocity, session 80.10.20.90.30.40.20.10.20.71.00.50.80.20.1-0.1-0.1-0.10.10.30.3
Locomotion distance, session 80.10.10.40.60.60.50.50.60.2-0.30.40.2-0.30.1-0.1-0.1-0.10.10.2-0.0
Degree of sensitization distance0.90.92.0-0.10.1-0.3-0.20.00.20.4-0.30.41.41.4-1.4-1.4-1.41.41.21.3
Degree of sensitization stereotypy0.90.92.71.61.61.51.31.41.30.31.00.1-0.5-0.50.50.50.5-0.50.40.1
Conditioned locomotion1.01.12.5-1.1-1.3-1.0-1.0-1.2-1.3-0.7-0.7-1.0-1.3-0.70.70.70.7-0.7-1.6-1.6
Cocaine response after cond. corrected0.10.10.4-0.6-0.6-0.5-0.4-0.6-0.10.30.20.10.20.0-0.0-0.0-0.00.0-0.2-0.0
Cocaine response after cond. not corrected0.10.10.30.20.10.20.40.10.3-0.20.5-0.4-0.3-0.50.50.50.5-0.5-0.3-0.3
Cocaine response before conditioning1.62.03.31.71.51.81.71.31.0-1.11.0-1.5-1.3-1.61.61.61.6-1.6-0.5-0.7
Saline control response0.30.40.9-0.2-0.1-0.6-0.4-0.0-0.2-0.1-0.40.80.71.0-1.0-1.0-1.01.00.70.6
Bone: connectivity density0.40.61.51.01.11.11.11.20.6-0.60.6-0.3-0.5-0.60.60.60.6-0.60.3-0.0
Bone: cortical apparent density0.50.72.1-1.3-1.3-1.2-1.2-1.5-0.31.1-0.40.60.70.5-0.5-0.5-0.50.5-0.40.0
Bone: cortical area2.03.17.62.72.52.82.72.22.3-0.72.3-1.2-0.4-1.11.11.11.1-1.10.50.4
Bone: cortical porosity0.40.41.71.01.00.90.81.30.1-0.7-0.1-0.4-0.8-0.30.30.30.3-0.30.3-0.2
Bone: cortical porosity0.20.21.00.70.70.30.31.0-0.3-0.5-0.6-0.0-0.70.2-0.2-0.2-0.20.20.4-0.2
Bone: cortical thickness1.11.86.22.11.91.91.81.22.50.52.2-0.50.8-0.20.20.20.2-0.20.91.1
Bone: cortical thickness1.01.25.01.31.31.00.90.32.21.12.00.11.40.2-0.2-0.2-0.20.21.01.4
Bone: cortical tissue density0.50.72.1-1.3-1.3-1.2-1.2-1.4-0.41.0-0.50.60.60.5-0.5-0.5-0.50.5-0.40.0
Condit. Reinf. active minus inactive responses0.30.30.6-0.3-0.2-0.5-0.40.0-0.7-0.2-0.80.70.10.7-0.7-0.7-0.70.70.30.2
Condit. Reinf. active-inactive response ratio0.20.20.8-0.2-0.1-0.3-0.20.3-0.9-0.5-0.80.3-0.50.3-0.3-0.3-0.30.30.0-0.3
Condit. Reinf. active responses0.20.30.5-0.2-0.2-0.4-0.3-0.0-0.6-0.6-0.60.50.50.7-0.7-0.7-0.70.70.50.5
Condit. Reinf. inactive responses0.10.10.60.00.00.10.00.10.0-0.6-0.00.10.80.3-0.3-0.3-0.30.30.50.7
Incentive salience index mean0.20.21.1-0.1-0.2-0.10.00.1-0.7-1.1-0.5-0.4-0.7-0.40.40.40.4-0.4-0.5-0.6
Condit. Reinf. lever presses0.70.92.6-0.5-0.7-0.2-0.1-0.2-1.1-1.6-0.6-1.1-1.2-1.01.01.01.0-1.0-1.1-1.3
Condit. Reinf. active minus inactive responses0.71.02.90.71.10.90.91.7-0.2-1.4-0.50.80.60.8-0.8-0.8-0.80.81.61.1
Condit. Reinf. active-inactive response ratio0.81.02.3-0.00.40.10.11.0-0.7-1.0-1.01.11.01.2-1.2-1.2-1.21.21.51.2
Condit. Reinf. active responses0.40.52.10.70.90.90.81.5-0.2-1.3-0.30.50.10.2-0.2-0.2-0.20.21.00.6
Condit. Reinf. inactive responses1.01.32.11.10.81.21.10.80.5-0.61.0-1.1-1.3-1.51.51.51.5-1.5-0.7-0.9
Condit. Reinf. lever presses0.70.93.91.31.51.71.52.00.2-1.20.30.2-0.3-0.20.20.20.2-0.21.00.4
Condit. Reinf. lever reinforcers received0.30.41.50.40.60.60.51.2-0.6-1.2-0.60.60.10.4-0.4-0.4-0.40.40.90.5
Conditioned reinforcement - actives0.40.63.10.70.90.20.10.21.41.71.10.40.90.4-0.4-0.4-0.40.40.80.9
Conditioned reinforcement - inactives0.30.41.3-0.9-0.6-0.8-0.9-1.10.11.00.30.61.20.2-0.2-0.2-0.20.20.10.6
Conditioned locomotion0.00.00.3-0.1-0.1-0.4-0.3-0.40.00.50.20.10.30.1-0.1-0.1-0.10.1-0.00.1
Patch foraging indifference point 0 sec1.01.93.81.11.40.40.81.41.11.10.71.71.21.6-1.6-1.6-1.61.61.91.7
Patch foraging indifference point AUC0.40.51.10.70.81.11.00.71.0-0.21.10.11.0-0.10.10.10.1-0.10.81.0
Delay disc. indifference point, 0s delay0.91.02.90.70.71.21.10.11.3-0.21.7-1.0-0.3-1.21.21.21.2-1.2-0.7-0.3
Delay disc. indifference point, 16s delay3.13.47.3-1.9-1.6-2.4-2.3-1.9-0.52.7-1.22.01.42.0-2.0-2.0-2.02.00.40.7
Delay disc. indifference point, 2s delay2.62.95.82.22.02.32.41.72.0-1.12.1-1.5-0.7-1.61.61.61.6-1.6-0.1-0.1
Delay disc. indifference point, 24s delay1.71.95.0-1.7-1.8-2.2-2.2-2.1-0.81.8-1.11.30.60.9-0.9-0.9-0.90.9-0.4-0.1
Delay disc. indifference point, 4s delay0.60.62.80.80.70.20.3-0.11.71.21.50.31.10.1-0.1-0.1-0.10.10.50.9
Delay disc. indifference point, 8s delay0.20.21.10.40.30.00.1-0.30.91.00.8-0.4-0.0-0.20.20.20.2-0.2-0.3-0.1
Indifference point function ln k0.10.20.80.70.60.30.40.50.6-0.10.9-0.5-0.1-0.10.10.10.1-0.10.20.1
Indifference point function log k0.10.20.80.70.60.30.40.50.6-0.10.9-0.5-0.1-0.10.10.10.1-0.10.20.1
Patch foraging total patch changes 0 sec1.22.34.81.21.50.50.81.61.11.00.71.81.31.8-1.8-1.8-1.81.82.21.8
Patch foraging total patch changes 12 sec0.10.10.50.20.40.40.50.70.1-0.20.10.60.20.3-0.3-0.3-0.30.30.50.4
Patch foraging total patch changes 18 sec0.40.61.80.10.3-0.00.20.10.50.80.41.31.20.9-0.9-0.9-0.90.90.91.1
Patch foraging total patch changes 24 sec0.61.12.31.21.40.90.91.21.10.70.51.11.00.9-0.9-0.9-0.90.91.51.4
Patch foraging total patch changes 6 sec3.24.99.20.20.8-0.4-0.20.51.22.20.53.03.02.8-2.8-2.8-2.82.82.93.0
Patch foraging time to switch 0 sec1.63.26.7-2.4-2.6-2.0-2.0-2.2-2.5-0.0-2.2-0.5-1.8-0.60.60.60.6-0.6-2.4-2.4
Patch foraging water rate 0 sec0.10.30.80.90.80.70.70.90.6-0.10.7-0.20.1-0.00.00.00.0-0.00.60.4
Patch foraging water rate 12 sec1.02.14.42.02.11.31.31.72.01.01.30.81.20.9-0.9-0.9-0.90.92.01.8
Patch foraging water rate 18 sec0.50.71.71.31.20.60.51.20.90.80.50.50.40.8-0.8-0.8-0.80.81.30.9
Patch foraging water rate 24 sec0.40.61.91.41.30.90.90.71.30.11.1-0.30.60.1-0.1-0.1-0.10.10.70.8
Patch foraging water rate 6 sec0.60.83.30.40.50.10.10.20.70.40.81.01.80.9-0.9-0.9-0.90.91.31.7
Seeking ratio, delayed vs. immediate footshock0.10.10.20.30.30.50.20.40.2-0.10.2-0.30.20.3-0.3-0.3-0.30.30.40.3
Distance traveled before self-admin0.30.41.51.00.60.70.40.20.90.31.2-0.60.7-0.30.30.30.3-0.30.40.6
Distance traveled after self-admin1.62.04.11.51.41.71.60.81.6-0.22.0-1.8-0.4-1.61.61.61.6-1.6-0.4-0.2
Extensor digitorum longus weight3.212.823.54.13.64.84.83.22.7-2.63.6-3.9-2.8-3.93.93.93.9-3.9-1.2-1.5
Bone: elastic displacement0.91.12.2-0.2-0.1-0.6-0.8-0.40.21.4-0.31.51.41.2-1.2-1.2-1.21.21.01.2
Bone: elastic work0.30.41.11.11.00.90.80.70.80.00.90.10.4-0.10.10.10.1-0.10.60.6
Bone: endosteal estimation1.22.64.21.51.42.02.01.80.2-2.00.9-1.5-1.8-1.91.91.91.9-1.9-0.6-1.1
Bone: endosteal perimeter1.22.54.30.90.71.51.51.0-0.1-2.10.7-1.7-1.9-2.12.12.12.1-2.1-1.2-1.5
Epididymis fat weight0.51.96.22.12.22.12.12.51.3-1.31.0-0.10.2-0.20.20.20.2-0.21.51.0
Delta time in closed arm before/after self-admin1.41.33.4-0.3-0.40.40.5-0.2-0.3-0.5-0.4-1.4-1.8-1.41.41.41.4-1.4-1.7-1.8
Delta time in open arm before/after self-admin0.90.92.31.11.41.31.51.50.9-1.21.00.10.4-0.20.20.20.2-0.21.00.9
Diff in mean of infusions in LGA sessions1.31.63.3-0.20.1-0.3-0.30.3-0.2-0.0-0.21.51.81.7-1.7-1.7-1.71.71.71.8
Delay discount exponential model param0.30.32.20.10.10.60.40.7-0.8-1.5-0.4-0.4-0.5-0.30.30.30.3-0.30.0-0.3
Extinction: sum of active levers before priming0.50.51.7-1.3-1.2-1.0-0.8-0.8-1.3-0.4-1.00.4-0.20.1-0.1-0.1-0.10.1-0.5-0.5
Active lever presses in extinction session 60.10.10.30.20.2-0.00.10.4-0.2-0.0-0.10.20.10.5-0.5-0.5-0.50.50.50.3
Bone: final force3.04.811.93.23.03.43.32.82.5-1.32.9-1.6-0.5-1.51.51.51.5-1.50.70.4
Bone: final moment2.54.110.43.12.93.23.12.82.4-1.02.7-1.2-0.2-1.11.11.11.1-1.11.00.7
Food consumed during 24 hour testing period1.01.43.11.21.31.81.71.20.8-1.51.5-1.1-0.2-1.21.21.21.2-1.20.10.2
Glucose0.10.20.70.20.2-0.1-0.2-0.10.30.90.30.30.60.6-0.6-0.6-0.60.60.50.5
Heart weight0.10.10.30.30.30.40.50.40.4-0.00.4-0.10.3-0.10.10.10.1-0.10.30.3
Delay discount hyperbolic model param0.20.21.3-0.3-0.20.20.10.3-0.9-1.1-0.6-0.2-0.3-0.10.10.10.1-0.1-0.0-0.2
Intermittent access intake day 1-15 change0.30.62.3-1.2-1.2-0.8-1.0-1.5-0.50.20.30.10.4-0.70.70.70.7-0.7-0.9-0.3
Intermittent access intake escalation0.30.62.5-1.1-1.1-0.9-1.1-1.6-0.30.70.40.30.6-0.40.40.40.4-0.4-0.7-0.0
Intermittent access intake escalation 20.70.73.1-1.2-1.2-0.9-1.1-1.7-0.11.00.7-0.00.5-0.60.60.60.6-0.6-1.0-0.3
Intermitt. access day 1 inactive lever presses0.10.31.5-1.2-1.0-0.7-0.6-1.1-0.5-0.2-0.30.10.5-0.20.20.20.2-0.2-0.5-0.0
Intermitt. access day 15 inactive lever presses0.20.40.80.20.30.60.50.30.3-0.40.7-0.5-0.4-0.90.90.90.9-0.9-0.4-0.3
Intermitt. access escalation Index0.10.21.30.30.30.50.60.8-0.2-1.10.20.20.3-0.00.00.00.0-0.00.60.5
Intermittent access day 1 total infusions0.30.51.61.01.20.90.91.30.1-1.10.30.6-0.20.1-0.1-0.1-0.10.10.70.3
Intermittent access day 15 total infusions0.00.10.4-0.10.0-0.1-0.1-0.2-0.1-0.20.40.60.4-0.10.10.10.1-0.10.10.3
Intermittent access terminal intake (last 3 days)0.10.10.30.40.40.30.30.30.0-0.50.60.50.4-0.10.10.10.1-0.10.40.4
Intermittent access total infusions0.60.72.21.41.51.11.11.30.8-0.61.10.10.2-0.10.10.10.1-0.10.80.7
Intermittent access day 1 locomotion0.30.41.00.80.90.60.60.90.1-0.80.31.00.40.4-0.4-0.4-0.40.40.90.7
Intermittent access day 15 total locomotion0.40.82.4-0.10.1-0.3-0.30.1-0.10.00.11.51.41.0-1.0-1.0-1.01.01.21.3
Intermittent access total locomotion0.60.72.00.80.90.50.51.10.1-0.90.21.10.90.7-0.7-0.7-0.70.71.41.2
Intermittent access standard deviation0.71.54.70.70.91.21.20.41.2-0.42.2-0.3-0.1-1.71.71.71.7-1.7-0.4-0.0
Left kidney weight1.36.014.03.73.53.73.63.32.6-1.73.2-1.6-0.6-1.71.71.71.7-1.70.90.5
Right kidney weight1.56.817.54.24.04.04.03.93.1-1.23.2-1.4-0.3-1.31.31.31.3-1.31.61.1
Cocaine induced anxiety0.30.41.3-0.7-1.0-0.4-0.4-0.6-1.0-1.2-0.6-0.50.1-0.50.50.50.5-0.5-0.5-0.3
Post-drug Anxiety0.60.61.9-0.4-0.4-0.7-0.7-0.4-0.20.4-0.20.81.41.0-1.0-1.0-1.01.00.81.1
Baseline Anxiety1.41.64.21.11.40.40.30.71.72.11.30.91.21.2-1.2-1.2-1.21.21.51.5
Tail length0.52.16.52.42.51.81.71.82.51.41.60.20.50.4-0.4-0.4-0.40.41.31.1
Length with tail0.31.46.41.61.50.50.50.81.92.50.80.60.11.1-1.1-1.1-1.11.10.90.6
Length without tail0.31.05.9-0.3-0.5-1.3-1.3-1.10.32.4-0.10.50.11.1-1.1-1.1-1.11.1-0.2-0.2
Times rat made contact with spout2.32.65.20.70.61.51.30.40.3-2.11.3-2.0-1.1-2.32.32.32.3-2.3-1.2-1.0
Lifetime Intake0.81.03.41.81.81.41.31.61.1-0.51.2-0.20.1-0.20.20.20.2-0.20.90.7
Liver weight, left0.30.52.4-1.0-0.8-0.8-0.7-0.0-1.3-0.0-1.60.5-0.60.4-0.4-0.4-0.40.4-0.1-0.5
Liver weight, right0.30.62.2-0.7-0.7-0.7-0.5-0.2-1.10.0-1.5-0.2-1.4-0.20.20.20.2-0.2-0.8-1.3
Locomotor activity0.00.10.4-0.2-0.00.00.10.3-0.20.1-0.60.7-0.30.1-0.1-0.1-0.10.10.0-0.2
Locomotor testing distance0.10.10.40.20.40.40.50.60.20.1-0.20.60.00.1-0.1-0.1-0.10.10.40.2
Locomotor testing rearing0.20.31.8-0.2-0.1-0.3-0.20.3-0.9-0.6-1.40.6-0.20.6-0.6-0.6-0.60.60.3-0.0
Locomotion in novel chamber0.60.82.31.21.00.70.71.50.1-0.6-0.30.40.50.8-0.8-0.8-0.80.81.51.0
Locomotion in novel chamber post-restriction0.91.42.7-0.3-0.1-0.7-0.50.4-0.01.2-0.61.51.61.5-1.5-1.5-1.51.51.71.5
Fecal boli incidents, locomotor time 10.71.03.9-0.8-1.0-0.6-1.1-0.4-2.0-1.3-1.9-0.4-1.3-0.20.20.20.2-0.2-0.9-1.3
Change in fecal boli incidents, locomotor task2.72.76.32.11.90.70.91.32.51.91.61.51.81.1-1.1-1.1-1.11.12.22.2
Time >=10cm from walls, locomotor time 10.50.51.20.80.71.10.70.50.7-0.01.0-0.7-0.2-0.90.90.90.9-0.9-0.1-0.1
Bouts of movement, locomotor time 11.92.16.1-2.1-2.3-2.0-2.1-1.7-2.5-0.9-1.91.00.60.9-0.9-0.9-0.90.9-0.3-0.1
Total resting periods, locomotor time 12.12.36.1-2.2-2.4-2.2-2.3-1.9-2.5-0.5-2.11.00.30.8-0.8-0.8-0.80.8-0.6-0.4
Rest time, locomotor task time 10.81.02.7-0.7-1.3-1.2-1.4-1.6-0.90.5-0.9-0.1-0.8-0.50.50.50.5-0.5-1.5-1.3
Distance moved, locomotor task time 10.71.12.81.21.41.11.51.71.0-0.21.00.40.80.5-0.5-0.5-0.50.51.51.3
Vertical activity count, locomotor time 10.71.64.21.31.71.92.01.51.8-0.22.0-0.21.2-0.30.30.30.3-0.31.21.5
Time >=10cm from walls, locomotor time 21.11.63.01.51.41.61.51.01.3-0.51.7-1.5-0.7-1.41.41.41.4-1.4-0.2-0.3
Bouts of movement, locomotor time 21.01.65.5-0.3-0.60.20.20.4-2.0-2.3-1.3-1.1-2.2-0.90.90.90.9-0.9-1.4-1.9
Total resting periods, locomotor time 20.81.44.80.0-0.30.40.50.6-1.6-2.1-1.0-1.1-2.2-0.90.90.90.9-0.9-1.3-1.9
Rest time, locomotor task time 20.20.21.30.90.50.1-0.00.20.81.10.30.40.20.3-0.3-0.3-0.30.30.40.3
Distance moved, locomotor task time 20.40.52.00.10.20.70.9-0.10.3-0.91.4-1.00.1-0.80.80.80.8-0.8-0.5-0.1
Vertical activity count, locomotor time 20.40.52.50.30.60.80.80.01.10.31.6-0.11.2-0.20.20.20.2-0.20.41.0
Light reinforcement 10.30.71.9-0.2-0.0-0.4-0.40.3-0.31.0-0.71.40.31.1-1.1-1.1-1.11.10.80.5
Light reinforcement 20.30.40.90.10.2-0.1-0.10.5-0.30.4-0.40.90.40.9-0.9-0.9-0.90.90.90.6
Bone: marrow area1.12.43.91.41.31.91.91.70.2-2.00.8-1.4-1.7-1.81.81.81.8-1.8-0.6-1.0
Bone: maximum diameter1.42.66.32.12.02.52.52.21.4-1.31.6-1.2-0.9-1.41.41.41.4-1.40.2-0.2
Bone: maximum force2.54.410.83.02.83.33.22.62.5-1.02.9-1.4-0.5-1.61.61.61.6-1.60.60.4
Bone: maximum moment2.13.69.12.92.73.02.92.52.3-0.82.6-1.0-0.2-1.11.11.11.1-1.10.90.6
Mean time between licks in bursts0.20.41.5-0.8-1.1-0.5-0.6-0.5-1.2-0.7-0.8-0.4-0.3-0.30.30.30.3-0.3-0.6-0.6
Mean num. licks in bursts2.74.310.33.23.23.13.23.11.9-2.01.9-1.2-0.9-1.31.31.31.3-1.30.90.3
Cd content in liver3.53.99.2-0.10.2-1.0-1.00.6-0.21.9-1.63.01.72.7-2.7-2.7-2.72.72.31.9
Co content in liver1.31.54.30.70.80.20.2-0.01.81.61.31.12.11.1-1.1-1.1-1.11.11.41.9
Cu content in liver0.91.02.31.51.41.21.11.31.50.31.00.30.90.5-0.5-0.5-0.50.51.41.3
Fe content in liver0.70.82.80.20.0-0.3-0.4-0.30.60.60.60.81.71.1-1.1-1.1-1.11.11.11.4
K content in liver0.20.10.70.40.40.50.50.7-0.0-0.90.3-0.10.20.0-0.0-0.0-0.00.00.50.4
Mg content in liver0.20.20.70.1-0.10.10.20.4-0.7-0.8-0.5-0.6-0.8-0.30.30.30.3-0.3-0.3-0.6
Mn content in liver0.40.51.10.40.30.60.70.5-0.1-1.10.1-0.9-0.7-0.80.80.80.8-0.8-0.4-0.5
Na content in liver4.44.89.91.21.12.32.21.5-0.0-3.11.2-3.0-2.2-2.72.72.72.7-2.7-1.3-1.7
Rb content in liver6.06.912.90.40.3-1.3-1.30.11.03.0-0.72.93.23.6-3.6-3.6-3.63.63.23.2
Se content in liver0.30.41.20.2-0.00.50.40.0-0.0-1.00.6-1.1-0.3-0.80.80.80.8-0.8-0.4-0.3
Sr content in liver0.60.51.50.20.50.90.90.7-0.1-1.20.2-0.4-0.7-0.80.80.80.8-0.8-0.3-0.5
Zn content in liver1.01.13.11.21.11.51.51.7-0.1-1.6-0.0-0.5-1.1-0.80.80.80.8-0.80.1-0.5
Bone: minimum diameter1.52.75.21.91.72.32.21.80.8-1.81.2-1.5-1.6-1.81.81.81.8-1.8-0.5-0.9
Time in familiar zone, hab. session 11.11.13.4-0.3-0.2-0.5-0.5-0.50.41.00.21.31.81.2-1.2-1.2-1.21.21.11.5
Time in novel zone, hab. session 11.11.15.20.90.60.50.60.60.0-0.2-0.2-1.0-2.3-1.11.11.11.1-1.1-1.2-1.7
Total zone transitions, hab. session 11.82.66.52.52.52.22.22.12.50.42.40.00.6-0.30.30.30.3-0.31.41.3
Total locomotion distance, hab. session 13.44.813.43.53.73.23.33.43.0-0.22.60.30.5-0.30.30.30.3-0.32.11.7
Locomotion velocity, hab. session 12.73.810.22.93.22.93.03.22.5-0.22.00.40.6-0.10.10.10.1-0.12.11.7
Time in familiar zone, hab. session 20.20.20.60.70.60.70.70.60.5-0.30.6-0.00.3-0.30.30.30.3-0.30.40.5
Time in novel zone, hab. session 20.10.10.2-0.2-0.1-0.3-0.30.0-0.20.1-0.40.3-0.10.4-0.4-0.4-0.40.40.1-0.0
Total zone transitions, hab. session 21.62.05.52.32.32.01.92.12.10.41.80.40.4-0.00.00.00.0-0.01.41.1
Total locomotion distance, hab. session 22.12.87.52.62.72.42.42.32.50.22.20.20.6-0.20.20.20.2-0.21.51.4
Locomotion velocity, hab. session 22.33.08.02.72.82.62.62.52.5-0.12.30.00.3-0.50.50.50.5-0.51.41.2
Novel to familiar place preference ratio0.40.51.4-1.2-1.0-0.9-0.8-1.1-0.40.3-0.20.61.00.5-0.5-0.5-0.50.50.00.5
Novelty place preference0.40.51.5-1.1-1.0-0.9-0.9-1.2-0.20.4-0.00.51.10.4-0.4-0.4-0.40.4-0.10.5
Time in novel zone, NPP test0.50.51.3-1.0-0.9-0.9-0.8-1.0-0.20.5-0.10.91.20.6-0.6-0.6-0.60.60.20.7
Total zone transitions, NPP test1.01.43.71.91.91.81.71.71.80.11.5-0.10.1-0.40.40.40.4-0.40.90.7
Total locomotion distance, NPP test1.11.53.81.81.91.91.91.61.8-0.51.70.00.6-0.40.40.40.4-0.41.01.1
Locomotion velocity, NPP test0.91.33.11.61.81.71.81.41.7-0.51.6-0.30.5-0.40.40.40.4-0.40.90.9
Intraocular pressure0.20.20.80.30.40.30.50.40.3-0.1-0.2-0.7-0.9-0.50.50.50.5-0.5-0.4-0.6
Delta distance traveled before/after self-admin0.40.51.30.50.70.60.90.70.3-0.20.3-0.8-1.1-0.70.70.70.7-0.7-0.5-0.8
Delta ambulatory time before/after self-admin0.80.91.40.70.90.91.20.70.6-0.70.9-1.2-1.2-1.11.11.11.1-1.1-0.7-0.8
Parametrial fat weight2.35.514.33.53.62.72.53.82.2-0.72.20.41.41.3-1.3-1.3-1.31.33.42.7
Pavlov. Cond. lever latency2.63.37.90.60.9-0.1-0.3-0.32.02.71.42.12.81.9-1.9-1.9-1.91.92.02.6
Pavlov. Cond. magazine entry latency3.74.816.30.80.51.61.71.8-1.3-4.0-0.8-2.9-3.1-2.32.32.32.3-2.3-1.5-2.3
Pavlov. Cond. change in total contacts4.95.210.9-0.3-0.80.50.60.0-1.8-3.2-1.2-3.1-3.3-2.62.62.62.6-2.6-2.8-3.2
Pavlov. Cond. index score3.34.211.1-0.1-0.40.70.80.9-1.8-3.3-1.4-2.6-3.2-2.22.22.22.2-2.2-2.0-2.7
Pavlov. Cond. latency score2.73.59.9-0.0-0.30.70.80.9-1.7-3.2-1.2-2.4-2.9-2.02.02.02.0-2.0-1.7-2.4
Pavlov. Cond. lever contacts3.44.09.90.1-0.20.80.91.0-1.6-3.1-1.1-2.5-3.1-2.32.32.32.3-2.3-1.9-2.6
Pavlov. Cond. magazine entry number3.44.311.5-0.00.2-0.8-1.0-0.81.63.41.12.93.12.3-2.3-2.3-2.32.32.12.7
Pavlov. Cond. intertrial magazine entries2.32.75.7-0.3-0.1-0.9-1.0-0.50.61.90.02.32.42.1-2.1-2.1-2.12.11.82.1
Pavlov. Cond. lever-magazine prob. diff.3.84.713.80.0-0.30.91.01.1-1.9-3.7-1.4-2.7-3.3-2.42.42.42.4-2.4-2.0-2.8
Pavlov. Cond. response bias4.65.713.3-0.0-0.40.80.90.7-1.8-3.5-1.2-3.1-3.6-2.72.72.72.7-2.7-2.5-3.2
Pavlov. Cond. lever latency0.50.72.7-1.3-1.4-1.3-1.2-1.6-0.40.9-0.50.10.20.3-0.3-0.3-0.30.3-0.8-0.3
Pavlov. Cond. magazine entry latency1.01.22.9-1.5-1.5-1.2-1.2-1.2-1.7-0.9-1.3-0.4-1.0-0.50.50.50.5-0.5-1.4-1.3
Pavlov. Cond. change in total contacts0.81.33.30.40.70.10.01.00.10.1-0.31.71.21.5-1.5-1.5-1.51.51.81.5
Pavlov. Cond. index score0.10.10.7-0.1-0.00.1-0.10.3-0.7-0.8-0.50.2-0.2-0.00.00.00.0-0.00.1-0.1
Pavlov. Cond. latency score0.10.10.6-0.1-0.10.1-0.00.3-0.6-0.8-0.4-0.0-0.4-0.30.30.30.3-0.3-0.1-0.3
Pavlov. Cond. lever contacts0.40.62.51.11.21.31.11.60.2-0.90.3-0.2-0.4-0.40.40.40.4-0.40.60.2
Pavlov. Cond. magazine entry number1.01.33.11.81.71.71.71.41.70.11.6-0.6-0.1-0.60.60.60.6-0.60.50.4
Pavlov. Cond. intertrial magazine entries1.11.74.91.91.92.02.12.21.1-0.91.1-0.9-0.8-0.90.90.90.9-0.90.50.0
Pavlov. Cond. lever-magazine prob. diff.0.10.20.8-0.4-0.3-0.2-0.30.1-0.9-0.8-0.70.1-0.4-0.10.10.10.1-0.1-0.1-0.3
Pavlov. Cond. response bias0.10.21.40.20.30.30.20.7-0.7-1.2-0.50.1-0.20.0-0.0-0.0-0.00.00.40.1
Time in closed arm before self-admin0.10.10.30.40.30.40.20.30.2-0.30.50.20.3-0.20.20.20.2-0.20.40.4
Time in closed arm after self-admin0.30.42.7-0.1-0.1-0.3-0.3-0.40.61.60.20.70.60.6-0.6-0.6-0.60.60.30.5
Time in open arm before self-admin0.70.71.7-1.3-1.2-1.3-1.2-1.2-0.90.9-1.10.0-0.10.5-0.5-0.5-0.50.5-0.6-0.5
Time in open arm after self-admin1.71.83.50.60.71.31.50.90.4-1.81.1-1.4-0.9-1.91.91.91.9-1.9-0.7-0.7
Bone: periosteal estimation2.24.610.02.72.53.23.12.61.6-1.92.1-1.8-1.5-2.12.12.12.1-2.1-0.2-0.6
Bone: periosteal perimeter1.22.14.51.71.62.12.01.90.6-1.61.0-1.1-1.3-1.41.41.41.4-1.4-0.1-0.6
Bone: post-yield work1.21.77.22.12.22.02.12.70.8-1.20.70.0-0.6-0.30.30.30.3-0.31.20.4
Progressive ratio test 1 active lever presses0.30.42.70.80.40.60.50.8-0.6-1.6-0.30.0-0.5-0.30.30.30.3-0.30.1-0.3
Progressive ratio test 1 breakpoint0.30.32.50.70.40.50.50.7-0.7-1.6-0.40.0-0.6-0.30.30.30.3-0.3-0.0-0.3
Progressive ratio test 1 inactive lever presses0.40.54.5-0.3-0.40.10.10.1-1.4-2.1-0.90.3-0.4-0.40.40.40.4-0.4-0.4-0.5
Progressive ratio test 2 active lever presses0.10.20.70.40.1-0.0-0.10.2-0.7-0.7-0.9-0.3-0.60.2-0.2-0.2-0.20.2-0.1-0.4
Progressive ratio test 2 breakpoint0.10.20.90.40.1-0.1-0.10.2-0.7-0.6-0.9-0.2-0.50.3-0.3-0.3-0.30.3-0.0-0.3
Progressive ratio test 2 inactive lever presses0.10.21.20.50.50.50.50.6-0.2-1.1-0.3-0.4-0.3-0.20.20.20.2-0.20.1-0.1
Incentive Sensitization - Responses0.20.20.90.2-0.2-0.3-0.2-0.1-0.5-0.4-0.9-1.0-0.90.0-0.0-0.0-0.00.0-0.6-0.8
Incentive Sensitization - Breakpoint0.10.20.80.3-0.0-0.2-0.20.0-0.4-0.4-0.8-0.9-0.80.1-0.1-0.1-0.10.1-0.4-0.6
Sum of active levers in priming session hrs 5-61.31.24.5-1.4-1.2-1.3-1.0-0.3-2.1-0.7-2.10.4-0.60.9-0.9-0.9-0.90.9-0.2-0.6
Progressive ratio0.60.92.40.50.80.20.30.71.01.50.10.80.91.1-1.1-1.1-1.11.11.31.2
Food seeking constrained by brief footshock0.60.71.3-1.1-0.9-1.1-1.0-1.0-0.60.0-0.61.10.90.9-0.9-0.9-0.90.90.20.4
Seeking ratio, punishment vs. effort0.71.14.5-0.2-0.50.0-0.1-0.4-1.0-2.1-0.1-1.0-1.2-1.11.11.11.1-1.1-1.3-1.3
Retroperitoneal fat weight1.46.117.53.33.62.42.34.21.8-0.40.51.11.22.1-2.1-2.1-2.12.13.92.8
Reaction time number correct0.30.72.1-1.0-0.8-1.0-1.1-0.6-1.20.1-1.51.0-0.20.6-0.6-0.6-0.60.6-0.2-0.4
Reaction time mean minus median0.10.10.40.30.20.40.40.40.2-0.40.70.30.5-0.20.20.20.2-0.20.40.5
Reaction time mean minus median AUC0.20.62.0-0.10.1-0.1-0.30.3-0.20.3-0.01.41.10.8-0.8-0.8-0.80.81.11.1
Reaction time num false alarms0.40.62.5-1.4-1.3-1.0-0.8-1.6-0.20.50.10.00.4-0.30.30.30.3-0.3-0.9-0.3
Reaction time num false alarms AUC0.30.51.7-1.3-1.2-0.9-0.7-1.3-0.40.4-0.2-0.2-0.1-0.30.30.30.3-0.3-1.0-0.6
Reaction time trials correct on left0.30.72.1-1.0-0.8-1.0-1.1-0.6-1.20.1-1.51.0-0.20.6-0.6-0.6-0.60.6-0.2-0.4
Reaction time trials on left0.40.72.2-1.0-0.8-1.1-1.2-0.6-1.30.0-1.51.0-0.30.6-0.6-0.6-0.60.6-0.2-0.4
Reaction time mean0.10.10.50.50.50.40.50.70.3-0.20.2-0.10.20.0-0.0-0.0-0.00.00.60.4
Reaction time mean AUC0.00.00.20.20.10.10.20.4-0.1-0.2-0.1-0.2-0.10.0-0.0-0.0-0.00.00.20.1
Median of all reaction times0.10.10.60.60.50.40.50.80.2-0.2-0.0-0.3-0.10.0-0.0-0.0-0.00.00.40.2
Reaction time omissions0.20.31.3-0.5-0.6-0.6-0.60.0-1.1-0.2-1.10.0-0.80.1-0.1-0.1-0.10.1-0.3-0.7
Reaction time false alarm rate0.30.51.0-0.7-0.8-0.3-0.1-1.00.30.40.7-0.8-0.0-0.80.80.80.8-0.8-1.0-0.5
Reaction time premature initiation rate1.31.82.81.21.11.31.50.70.9-1.51.3-1.5-1.1-1.71.71.71.7-1.7-0.8-0.8
Reaction time premature initiations0.50.91.80.50.40.50.70.10.1-1.20.3-0.9-1.3-1.31.31.31.3-1.3-1.1-1.1
Std. dev. reaction times0.10.20.70.60.60.50.50.70.50.20.50.40.50.2-0.2-0.2-0.20.20.80.7
Reaction time trials completed0.40.72.2-1.0-0.8-1.1-1.2-0.6-1.30.0-1.51.0-0.30.6-0.6-0.6-0.60.6-0.2-0.4
Reaction time trials AUC0.30.51.7-0.8-0.6-0.8-0.9-0.4-1.1-0.0-1.30.9-0.20.6-0.6-0.6-0.60.6-0.1-0.3
Run reversals in cocaine runway, females3.53.56.52.02.02.42.31.41.9-1.32.5-1.8-0.9-2.12.12.12.1-2.1-0.5-0.4
Run reversals in cocaine runway, males0.30.31.1-0.7-0.8-0.8-0.8-1.0-0.11.0-0.10.90.30.2-0.2-0.2-0.20.2-0.4-0.1
Latency to leave start box in cocaine runway1.21.43.10.40.6-0.1-0.30.50.31.3-0.21.81.31.5-1.5-1.5-1.51.51.61.4
Latency to leave start box in cocaine runway, F0.30.30.8-0.2-0.1-0.4-0.60.1-0.60.4-0.80.9-0.10.7-0.7-0.7-0.70.70.30.0
Latency to leave start box in cocaine runway, M2.11.94.10.91.00.20.20.71.11.50.41.51.91.6-1.6-1.6-1.61.62.02.0
Std. dev. time between licks in bursts0.50.74.7-0.5-0.40.20.20.5-1.3-2.2-0.8-0.5-0.6-0.70.70.70.7-0.7-0.3-0.5
Total sessions with >9 infusions2.83.411.23.33.12.82.73.02.0-0.51.7-1.0-0.8-0.80.80.80.8-0.81.00.4
Short access day 1 total inactive lever presses0.20.30.70.80.80.60.70.60.70.40.3-0.2-0.5-0.40.40.40.4-0.4-0.1-0.2
Short access day 10 total inactive lever presses0.41.13.5-1.7-1.7-1.5-1.5-1.9-1.30.2-0.90.0-0.2-0.10.10.10.1-0.1-1.2-0.8
Short access day 1 total infusions0.91.23.71.91.81.41.41.31.71.01.2-0.8-0.7-0.60.60.60.6-0.60.2-0.1
Short access day 10 total infusions1.21.54.52.11.91.81.72.00.9-0.81.0-0.5-1.0-0.80.80.80.8-0.80.4-0.1
Short access total infusions1.82.37.92.82.62.22.22.41.8-0.51.6-0.6-0.5-0.60.60.60.6-0.60.90.4
Short access day 1 locomotion0.50.72.11.31.10.60.60.51.41.51.4-0.50.1-0.30.30.30.3-0.30.20.3
Short access day 10 total locomotion1.22.25.11.91.52.12.12.00.4-2.30.8-0.6-0.9-1.41.41.41.4-1.40.1-0.3
Short access total locomotion2.22.68.02.82.82.22.22.72.00.11.60.30.4-0.00.00.00.0-0.01.71.3
One hour access (0.3 mA shock)0.30.31.90.30.00.20.10.6-0.9-1.4-0.70.60.10.4-0.4-0.4-0.40.40.60.3
Compulsive drug intake0.20.32.3-0.3-0.2-0.10.10.3-0.5-0.1-1.5-0.1-0.30.6-0.6-0.6-0.60.60.2-0.1
One hour access (shock baseline)0.10.21.2-0.1-0.1-0.2-0.3-0.1-0.4-0.50.31.10.80.3-0.3-0.3-0.30.30.50.7
Social response proportion0.60.72.7-0.10.1-0.3-0.30.5-0.5-0.0-0.71.60.51.1-1.1-1.1-1.11.11.00.7
Social responses0.60.82.1-1.2-1.0-1.0-1.0-0.4-1.40.1-1.31.50.10.8-0.8-0.8-0.80.80.1-0.1
Social time0.81.13.3-0.9-0.7-1.2-1.1-0.7-0.51.2-0.91.80.61.3-1.3-1.3-1.31.30.40.4
Soleus weight1.64.711.33.43.43.23.22.83.3-0.23.2-0.60.5-0.90.90.90.9-0.91.61.5
Bone: stiffness2.03.39.12.42.22.72.61.72.5-0.83.0-1.4-0.1-1.41.41.41.4-1.40.30.4
Tibialis anterior weight3.913.431.65.45.25.65.64.64.2-2.04.5-2.6-1.0-2.72.72.72.7-2.71.10.6
Time to tail flick, vehicle, before self-admin0.10.10.30.30.30.50.60.30.3-0.50.20.10.3-0.10.10.10.1-0.10.20.3
Time to tail flick, vehicle, after self-admin1.62.14.6-2.0-1.9-2.0-2.1-1.6-2.10.1-2.11.2-0.31.0-1.0-1.0-1.01.0-0.7-0.8
Time to tail flick, test, before self-admin0.40.51.1-0.4-0.50.20.0-0.4-0.1-0.20.0-0.3-0.4-1.11.11.11.1-1.1-0.9-0.7
Time to tail flick, test, after self-admin2.72.88.2-1.4-1.6-0.5-0.5-1.1-1.9-2.9-0.4-1.5-1.5-1.81.81.81.8-1.8-2.2-2.0
Delta time to tail flick, vehicle, before/after SA0.30.30.6-0.6-0.4-0.8-0.7-0.2-0.70.2-0.70.6-0.20.7-0.7-0.7-0.70.70.1-0.1
Delta time to tail flick, test, before/after SA0.40.42.80.0-0.00.20.30.2-0.6-1.70.2-1.0-0.6-0.60.60.60.6-0.6-0.4-0.5
Tibia length0.30.81.90.40.60.20.30.31.01.10.91.41.20.8-0.8-0.8-0.80.81.11.2
Ambulatory time before self-admin0.30.51.70.90.50.3-0.0-0.21.11.11.3-0.21.30.2-0.2-0.2-0.20.20.71.1
Ambulatory time after self-admin1.72.04.91.71.51.71.50.71.90.12.2-2.0-0.3-1.51.51.51.5-1.5-0.3-0.0
Bone: tissue strength0.20.20.30.30.10.30.3-0.10.2-0.30.5-0.5-0.2-0.60.60.60.6-0.6-0.3-0.2
Total heroin consumption0.70.82.8-0.5-0.5-0.8-0.8-0.0-1.30.3-1.70.8-0.31.2-1.2-1.2-1.21.20.3-0.2
Bone: trabecular number0.50.81.81.31.41.21.31.11.2-0.41.3-0.30.2-0.50.50.50.5-0.50.60.5
Bone: trabecular spacing1.01.34.5-1.6-1.6-1.2-1.3-0.9-2.1-0.7-2.0-0.3-1.1-0.00.00.00.0-0.0-1.0-1.3
Bone: trabecular thickness3.64.58.92.73.02.02.02.52.91.12.11.42.11.3-1.3-1.3-1.31.33.02.8
Bone: trabecular tissue density0.10.10.4-0.00.00.10.1-0.10.50.60.60.30.70.2-0.2-0.2-0.20.20.30.5
Water consumed over 24 hours1.62.25.5-1.1-1.4-0.6-0.7-1.8-0.7-0.60.2-1.6-1.2-1.81.81.81.8-1.8-2.4-1.8
Number of responses in last shaping day0.30.30.80.50.40.40.40.10.40.80.1-0.4-0.9-0.60.60.60.6-0.6-0.6-0.7