Hub : Genes

Saxo4

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Saxo4 0.03 0.02 7.0e-04 0.01 0.03 0.03 0.02 7.2e-02 5.0e-04 1.1e-03 2.8e-03
2 BLA mRNA stability Saxo4 0.04 0.03 8.7e-03 0.01 0.04 0.02 0.02 5.7e-02 4.3e-03 2.3e-02 2.7e-02
3 PL isoform ratio NM_145786.1 0.02 0.01 4.3e-03 0.01 0.02 0 0.01 1.9e-02 6.3e-03 8.2e-02 2.1e-02
4 NAcc gene expression Saxo4 0.02 0.01 1.8e-03 0.01 0.02 0.01 0.01 1.9e-03 6.6e-04 5.3e-03 3.2e-03
5 PL isoform ratio XM_006231016.5 0.05 0.03 4.1e-07 0.05 0.06 0.05 0.05 4.8e-06 6.9e-07 3.8e-06 7.4e-06
6 NAcc mRNA stability Saxo4 0.08 0.04 4.5e-14 0.1 0.1 0.09 0.1 1.6e-14 4.4e-15 8.2e-14 4.1e-15
7 PL mRNA stability Saxo4 0.12 0.08 3.9e-08 0.07 0.07 0.07 0.07 3.6e-08 1.3e-08 8.3e-08 3.6e-08
8 Brain mRNA stability Saxo4 0.13 0.06 4.3e-15 0.16 0.15 0.15 0.15 1.6e-14 3.9e-14 8.7e-14 3.6e-14
9 NAcc intron excision ratio chr1_216543190_216543687 0.01 0.01 7.2e-03 0.01 0.01 0.01 0.01 6.4e-03 1.9e-02 2.1e-02 1.6e-02
10 LHb mRNA stability Saxo4 0.25 0.14 4.2e-04 0.1 0.09 0.1 0.08 2.1e-03 3.9e-03 3.0e-03 5.0e-03
11 IL mRNA stability Saxo4 0.16 0.11 2.8e-03 0 0.04 0.05 0.01 2.9e-01 3.2e-02 2.4e-02 1.7e-01
12 OFC gene expression Saxo4 0.22 0.13 8.7e-04 0.04 0.04 0.03 0.02 4.0e-02 3.4e-02 7.9e-02 1.2e-01
13 Adipose mRNA stability Saxo4 0.04 0.03 7.4e-04 0.01 0.02 0.01 0.01 6.6e-02 2.6e-03 1.7e-02 1.3e-02
14 IC isoform ratio XM_006231016.5 0.13 0.08 2.2e-04 0.09 0.05 0.07 0.07 1.6e-04 4.5e-03 6.0e-04 6.1e-04
15 IC alternative TSS XM_006231016.5 0.07 0.05 8.9e-03 0.02 0.03 0.02 0.03 4.8e-02 1.7e-02 4.2e-02 2.6e-02
16 IC alternative TSS XM_063281660.1 0.07 0.05 8.9e-03 0.01 0.03 0.02 0.03 1.0e-01 1.6e-02 4.2e-02 2.5e-02
17 NAcc isoform ratio XM_006231016.5 0.02 0.02 2.7e-03 0.01 0.01 0 0.01 1.3e-02 3.4e-03 4.4e-02 1.7e-02
18 BLA isoform ratio XM_006231016.5 0.09 0.07 1.4e-03 0.04 0.03 0.03 0.03 2.4e-03 1.3e-02 8.5e-03 1.2e-02
19 pVTA isoform ratio XM_006231016.5 0.08 0.1 2.5e-03 0.01 -0 -0 -0 4.4e-02 7.5e-01 6.5e-01 7.0e-01
20 PL intron excision ratio chr1_216543815_216545639 0.03 0.02 4.1e-03 0.01 0 -0 0 1.5e-02 1.2e-01 8.5e-01 8.1e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.10.10.5-0.0-0.00.0-0.1-0.20.30.2-0.2-0.6-0.30.2-0.50.70.4-0.60.6-0.60.20.2-0.2
Area under the delay curve0.10.10.40.3-0.4-0.30.30.1-0.0-0.60.3-0.50.30.5-0.10.3-0.5-0.30.3-0.40.00.0-0.0
BMI with tail3.110.818.1-2.02.02.1-2.6-2.73.23.0-3.4-3.2-3.5-2.0-3.74.23.4-4.34.3-3.83.63.6-3.5
BMI without tail0.42.33.9-1.11.01.1-1.2-1.31.40.9-1.3-1.7-1.4-0.4-1.71.81.5-1.81.8-1.82.02.0-2.0
Body weight3.214.120.6-2.92.82.9-3.2-3.53.72.9-3.5-4.4-3.5-2.8-4.34.54.2-4.54.5-4.53.83.8-3.7
Weight adjusted by age1.23.65.0-1.71.91.8-1.9-1.81.92.2-2.2-1.2-2.2-2.1-1.81.71.7-1.81.8-1.62.02.0-2.0
Bone surface0.61.12.7-0.70.60.7-0.8-1.01.30.7-0.8-1.6-1.0-0.3-1.31.60.9-1.51.5-1.50.60.6-0.6
Bone volume0.20.31.2-0.10.00.1-0.3-0.40.70.3-0.4-0.9-0.50.1-0.71.10.8-1.01.0-0.90.10.1-0.0
Breakpoint value in progressive ratio session1.83.35.2-2.22.22.2-2.1-2.11.81.8-1.8-1.8-1.7-2.3-1.71.31.6-1.31.3-1.51.61.6-1.6
Number of licking bursts0.00.10.3-0.1-0.00.0-0.1-0.10.1-0.3-0.0-0.0-0.00.3-0.40.40.5-0.40.4-0.40.10.1-0.1
Context. condit. distance diff. score0.00.00.10.0-0.0-0.10.0-0.0-0.00.0-0.20.1-0.20.3-0.20.20.3-0.30.3-0.20.30.3-0.3
Locomotion velocity, session 10.20.31.4-0.30.50.4-0.5-0.30.51.2-0.6-0.2-0.6-0.7-0.10.1-0.3-0.20.2-0.00.70.7-0.7
Locomotion distance, session 11.41.83.2-1.11.21.2-1.3-1.21.41.8-1.6-1.0-1.5-1.7-1.11.11.1-1.21.2-1.01.61.6-1.6
Locomotion velocity, session 22.73.24.0-1.61.61.7-1.8-1.82.01.7-1.9-1.8-1.9-1.1-1.91.91.3-1.91.9-1.91.91.9-1.9
Locomotion distance, session 21.21.73.1-1.21.31.2-1.3-1.21.21.4-1.4-0.8-1.4-1.5-1.10.91.3-1.01.0-1.01.81.8-1.7
Locomotion velocity, session 30.60.72.0-0.1-0.00.0-0.2-0.40.60.2-0.6-0.7-0.6-0.0-1.11.40.9-1.41.4-1.20.80.8-0.8
Locomotion distance, session 30.30.41.30.5-0.6-0.60.60.5-0.5-0.80.7-0.10.71.20.4-0.4-0.80.4-0.40.3-0.7-0.70.7
Stereotopy head waving bouts, day 30.20.20.50.4-0.3-0.30.20.10.10.1-0.3-0.2-0.2-0.7-0.40.60.2-0.70.7-0.50.70.7-0.7
Stereotopy head waving duration, day 30.30.41.1-0.10.10.1-0.2-0.30.30.1-0.5-0.4-0.5-0.5-0.70.80.4-0.90.9-0.81.01.0-1.0
Locomotion velocity, session 70.10.10.90.3-0.4-0.30.30.1-0.1-0.60.2-0.20.20.9-0.10.2-0.7-0.20.2-0.3-0.1-0.10.1
Locomotion distance, session 70.10.10.40.3-0.3-0.30.30.2-0.2-0.60.2-0.20.20.5-0.10.1-0.6-0.20.2-0.20.20.2-0.2
Stereotopy head waving bouts, day 70.10.20.4-0.30.30.3-0.4-0.30.50.6-0.6-0.4-0.5-0.3-0.40.50.3-0.50.5-0.40.30.3-0.2
Stereotopy head waving duration, day 70.91.12.1-1.00.91.0-1.0-1.11.20.9-1.0-1.4-1.0-0.9-1.11.11.0-1.11.1-1.10.90.9-0.8
Locomotion velocity, session 80.10.10.3-0.20.10.10.1-0.0-0.1-0.40.3-0.30.3-0.40.3-0.50.40.5-0.50.20.00.0-0.0
Locomotion distance, session 80.10.10.40.1-0.1-0.1-0.0-0.00.10.2-0.40.1-0.3-0.1-0.30.40.3-0.40.4-0.30.60.6-0.6
Degree of sensitization distance0.91.01.9-0.30.40.4-0.6-0.60.80.8-1.0-0.3-1.1-1.3-1.01.20.8-1.31.3-1.11.41.4-1.4
Degree of sensitization stereotypy0.80.91.3-0.90.90.9-1.0-1.01.21.1-1.1-1.0-1.1-0.6-1.01.01.0-1.01.0-0.90.70.7-0.7
Conditioned locomotion0.50.61.1-0.80.80.8-0.8-0.90.80.5-0.6-0.9-0.6-0.7-0.90.8-0.0-0.90.9-0.90.80.8-1.0
Cocaine response after cond. corrected0.10.20.70.00.20.1-0.2-0.0-0.00.7-0.40.5-0.4-0.8-0.10.10.1-0.30.20.00.70.7-0.8
Cocaine response after cond. not corrected0.10.10.90.20.1-0.0-0.10.10.00.9-0.40.7-0.5-0.50.10.1-0.2-0.10.10.20.40.4-0.4
Cocaine response before conditioning0.10.20.9-0.00.10.0-0.10.10.30.7-0.30.2-0.30.40.3-0.1-0.10.2-0.20.4-0.7-0.70.9
Saline control response1.92.64.0-1.91.81.8-1.8-1.81.71.6-1.4-1.9-1.5-2.0-1.51.21.8-1.31.3-1.51.41.4-1.3
Bone: connectivity density0.81.32.4-0.90.80.9-1.0-1.11.31.0-1.1-1.6-1.2-0.4-1.31.50.8-1.51.5-1.41.11.1-1.1
Bone: cortical apparent density0.20.20.6-0.80.80.8-0.7-0.70.50.4-0.6-0.5-0.50.1-0.40.20.1-0.10.2-0.30.40.4-0.4
Bone: cortical area0.10.10.6-0.30.30.3-0.3-0.40.60.4-0.1-0.8-0.30.1-0.30.50.1-0.40.4-0.4-0.2-0.20.2
Bone: cortical porosity0.10.10.5-0.70.60.6-0.5-0.50.2-0.0-0.0-0.3-0.1-0.4-0.1-0.20.40.2-0.2-0.10.30.3-0.3
Bone: cortical porosity0.20.30.7-0.80.80.8-0.6-0.70.40.2-0.2-0.6-0.4-0.6-0.3-0.00.4-0.00.0-0.20.50.5-0.5
Bone: cortical thickness1.52.55.0-2.22.22.2-2.0-2.01.71.7-1.3-2.2-1.4-1.3-1.20.81.0-0.80.8-1.21.31.3-1.2
Bone: cortical thickness0.10.11.0-0.50.50.5-0.3-0.40.20.1-0.1-0.5-0.11.0-0.1-0.1-0.70.1-0.1-0.00.00.00.0
Bone: cortical tissue density0.30.41.0-1.01.01.0-0.9-0.90.70.6-0.8-0.7-0.7-0.0-0.60.30.2-0.30.3-0.50.60.6-0.6
Condit. Reinf. active minus inactive responses1.82.04.9-1.31.51.4-1.5-1.31.62.2-1.7-0.8-1.6-1.9-1.21.11.4-1.21.2-0.91.31.3-1.3
Condit. Reinf. active-inactive response ratio1.51.64.4-1.41.61.5-1.5-1.21.32.1-1.3-0.5-1.4-2.0-0.80.61.1-0.70.7-0.51.31.3-1.3
Condit. Reinf. active responses1.52.04.6-1.11.21.2-1.4-1.21.62.1-1.8-0.7-1.7-1.4-1.31.41.4-1.51.4-1.11.31.3-1.3
Condit. Reinf. inactive responses0.10.10.40.4-0.3-0.30.10.10.20.3-0.40.3-0.30.5-0.30.70.4-0.60.6-0.30.00.0-0.0
Incentive salience index mean1.01.33.1-0.91.00.9-1.1-1.01.41.8-1.4-0.8-1.3-1.2-1.01.21.0-1.21.2-0.91.01.0-1.0
Condit. Reinf. lever presses0.10.20.6-0.10.00.0-0.2-0.20.70.5-0.5-0.6-0.40.1-0.50.80.1-0.70.7-0.60.10.1-0.0
Condit. Reinf. active minus inactive responses0.10.10.7-0.00.20.1-0.2-0.00.20.8-0.30.7-0.2-0.30.00.1-0.1-0.00.00.2-0.2-0.20.2
Condit. Reinf. active-inactive response ratio0.10.20.70.2-0.1-0.1-0.1-0.00.30.4-0.50.8-0.5-0.1-0.50.80.6-0.70.7-0.40.20.2-0.3
Condit. Reinf. active responses0.10.10.8-0.30.40.4-0.4-0.30.40.9-0.50.2-0.4-0.5-0.10.20.0-0.20.20.0-0.0-0.00.1
Condit. Reinf. inactive responses0.20.30.70.1-0.0-0.10.20.3-0.30.20.4-0.10.50.10.8-0.9-0.80.8-0.80.8-0.7-0.70.9
Condit. Reinf. lever presses0.71.02.0-0.70.70.7-0.9-0.91.11.2-1.3-0.5-1.2-0.7-1.11.41.3-1.31.3-1.10.70.7-0.5
Condit. Reinf. lever reinforcers received0.30.41.6-0.70.80.7-0.8-0.60.81.3-0.90.0-0.8-0.8-0.50.50.5-0.50.5-0.30.30.3-0.2
Conditioned reinforcement - actives0.00.20.70.1-0.0-0.10.10.2-0.10.50.00.90.10.80.4-0.3-0.40.4-0.40.6-0.6-0.60.6
Conditioned reinforcement - inactives0.00.10.50.3-0.3-0.30.10.10.20.4-0.40.3-0.40.7-0.30.70.4-0.60.6-0.3-0.1-0.10.1
Conditioned locomotion1.21.84.21.8-1.8-1.81.71.6-1.3-1.11.21.41.22.11.1-0.6-1.30.7-0.71.0-1.2-1.21.2
Patch foraging indifference point 0 sec0.20.51.5-0.70.60.7-0.7-0.70.60.4-0.6-1.2-0.6-1.2-0.60.60.7-0.60.6-0.70.80.8-0.5
Patch foraging indifference point AUC0.40.91.4-1.21.21.2-1.2-1.11.21.0-1.0-1.1-1.0-0.7-0.80.70.8-0.70.7-0.80.60.6-0.6
Delay disc. indifference point, 0s delay0.10.10.40.6-0.7-0.60.40.4-0.3-0.20.30.20.30.2-0.10.5-0.2-0.50.5-0.30.10.1-0.1
Delay disc. indifference point, 16s delay0.00.00.10.1-0.1-0.10.0-0.10.3-0.0-0.2-0.2-0.20.3-0.20.4-0.1-0.30.3-0.30.10.1-0.1
Delay disc. indifference point, 2s delay0.60.71.71.2-1.3-1.21.11.0-0.7-0.90.80.50.80.80.6-0.1-0.80.2-0.20.4-0.9-0.90.9
Delay disc. indifference point, 24s delay0.00.10.30.2-0.2-0.20.20.10.1-0.40.2-0.30.20.6-0.00.1-0.5-0.10.1-0.10.00.0-0.0
Delay disc. indifference point, 4s delay0.20.21.00.1-0.3-0.20.2-0.10.0-0.70.2-1.00.20.3-0.40.6-0.2-0.50.5-0.70.40.4-0.4
Delay disc. indifference point, 8s delay0.30.52.20.7-0.8-0.70.80.6-0.9-1.50.9-0.00.90.70.5-0.5-1.20.5-0.50.3-0.4-0.40.4
Indifference point function ln k0.82.44.32.1-2.0-2.11.91.9-1.8-1.41.51.91.41.61.4-1.0-1.31.0-1.01.4-1.0-1.01.2
Indifference point function log k0.82.44.32.1-2.0-2.11.91.9-1.8-1.41.51.91.41.61.4-1.0-1.31.0-1.01.4-1.0-1.01.2
Patch foraging total patch changes 0 sec0.20.51.5-0.80.80.8-0.7-0.80.50.5-0.6-1.2-0.6-1.2-0.60.40.6-0.40.4-0.60.80.8-0.5
Patch foraging total patch changes 12 sec5.06.79.3-3.02.93.0-2.9-2.92.62.3-2.6-3.0-2.5-2.6-2.52.12.3-2.12.1-2.52.52.5-2.4
Patch foraging total patch changes 18 sec0.30.73.0-1.01.01.0-1.0-0.90.91.0-0.7-0.8-0.6-1.7-0.50.41.0-0.40.4-0.50.50.5-0.4
Patch foraging total patch changes 24 sec2.06.79.4-2.62.42.5-2.6-2.72.62.0-2.3-3.1-2.3-2.6-2.82.72.7-2.72.7-2.92.52.5-2.5
Patch foraging total patch changes 6 sec0.40.72.0-0.90.70.8-0.8-0.90.80.4-0.7-1.4-0.7-0.8-0.90.91.2-0.80.9-1.00.80.8-0.6
Patch foraging time to switch 0 sec0.10.41.1-0.20.20.2-0.4-0.40.70.4-0.7-0.4-0.6-0.3-0.81.00.5-1.01.0-0.80.30.3-0.5
Patch foraging water rate 0 sec0.31.11.90.8-0.8-0.80.91.0-1.3-0.81.00.90.91.01.3-1.4-1.01.4-1.41.3-0.9-0.91.1
Patch foraging water rate 12 sec0.51.83.41.4-1.4-1.41.51.5-1.8-1.31.41.41.30.91.5-1.5-0.71.4-1.41.5-1.0-1.01.0
Patch foraging water rate 18 sec0.40.91.41.0-1.1-1.11.11.0-1.2-1.11.10.51.01.00.9-0.9-1.10.8-0.80.8-0.7-0.70.8
Patch foraging water rate 24 sec1.01.52.51.1-1.1-1.21.31.2-1.6-1.21.31.31.21.21.3-1.3-0.91.3-1.31.3-1.1-1.11.2
Patch foraging water rate 6 sec0.91.42.31.0-1.1-1.11.21.2-1.5-1.31.40.91.30.61.3-1.4-0.91.4-1.41.2-0.9-0.91.0
Seeking ratio, delayed vs. immediate footshock0.10.20.8-0.0-0.00.0-0.1-0.20.2-0.0-0.2-0.1-0.2-0.4-0.60.80.9-0.70.7-0.70.40.4-0.5
Distance traveled before self-admin0.81.73.1-1.11.11.1-1.3-1.31.51.5-1.4-1.0-1.4-1.2-1.41.61.8-1.51.5-1.40.90.9-0.8
Distance traveled after self-admin0.30.50.8-0.90.90.9-0.9-0.80.70.9-0.7-0.4-0.8-0.5-0.70.60.8-0.60.6-0.60.60.6-0.5
Extensor digitorum longus weight5.823.027.4-4.64.54.6-4.8-5.05.04.2-4.7-5.1-4.9-3.4-5.25.04.4-5.15.1-5.25.05.0-4.9
Bone: elastic displacement0.20.31.20.00.10.00.20.3-0.5-0.10.40.30.40.00.7-1.1-0.71.0-1.00.8-0.1-0.10.1
Bone: elastic work0.70.91.7-1.31.31.3-1.1-1.10.91.0-0.6-1.3-0.7-1.1-0.70.30.9-0.40.4-0.61.01.0-1.0
Bone: endosteal estimation1.02.55.82.3-2.4-2.32.11.9-1.4-1.81.51.61.41.90.9-0.2-1.20.3-0.30.7-1.5-1.51.5
Bone: endosteal perimeter1.63.98.52.8-2.9-2.82.52.4-1.7-2.21.82.11.82.31.2-0.4-1.30.6-0.61.0-2.0-2.02.0
Epididymis fat weight0.42.15.42.3-2.3-2.32.01.9-1.4-1.51.31.51.20.51.0-0.20.00.4-0.40.8-1.4-1.41.5
Delta time in closed arm before/after self-admin3.12.96.3-1.81.71.7-1.7-1.81.21.1-1.2-2.0-1.3-2.5-1.71.31.8-1.51.5-1.72.02.0-2.0
Delta time in open arm before/after self-admin1.41.72.8-1.41.41.4-1.5-1.41.71.5-1.6-0.9-1.6-0.2-1.41.40.6-1.31.3-1.21.11.1-1.1
Diff in mean of infusions in LGA sessions1.83.24.6-2.12.12.1-2.1-2.11.71.6-1.6-2.0-1.6-2.1-1.81.51.5-1.51.5-1.81.71.7-1.7
Delay discount exponential model param0.10.10.4-0.30.50.4-0.3-0.20.00.7-0.30.5-0.3-0.60.1-0.30.60.3-0.30.40.00.0-0.0
Extinction: sum of active levers before priming2.03.14.2-1.71.61.7-1.7-1.81.91.2-1.9-2.0-1.9-1.4-1.91.81.2-1.81.8-2.01.91.9-1.8
Active lever presses in extinction session 61.81.82.9-1.51.51.5-1.5-1.51.61.4-1.6-1.2-1.7-0.8-1.41.31.2-1.21.2-1.31.11.1-1.1
Bone: final force0.50.91.5-0.80.80.8-0.9-1.01.21.0-0.8-1.2-1.0-0.5-1.11.20.8-1.11.1-1.10.60.6-0.6
Bone: final moment0.60.91.5-0.90.80.9-0.9-1.01.21.1-0.8-1.2-1.0-0.6-1.01.10.8-1.11.1-1.10.70.7-0.7
Food consumed during 24 hour testing period0.30.50.90.5-0.5-0.50.60.6-0.6-0.20.60.80.60.60.8-0.8-0.60.9-0.90.9-0.9-0.91.0
Glucose1.62.65.52.3-2.2-2.32.12.1-1.8-1.31.62.01.60.31.6-1.1-0.61.0-1.01.4-1.3-1.31.3
Heart weight0.30.41.31.1-1.1-1.10.90.7-0.5-1.00.50.10.50.7-0.00.4-0.6-0.50.5-0.30.00.0-0.0
Delay discount hyperbolic model param0.10.20.5-0.50.60.5-0.5-0.30.20.7-0.40.4-0.4-0.7-0.0-0.20.70.2-0.20.20.20.2-0.2
Intermittent access intake day 1-15 change0.42.03.41.4-1.3-1.41.41.5-1.2-0.81.21.81.21.51.5-1.3-1.11.4-1.41.6-1.7-1.71.7
Intermittent access intake escalation0.42.14.01.5-1.3-1.41.41.5-1.3-0.71.22.01.11.41.6-1.4-1.01.4-1.41.7-1.7-1.71.7
Intermittent access intake escalation 20.30.61.30.7-0.7-0.70.70.8-0.5-0.20.51.20.50.70.8-0.6-0.40.7-0.70.8-1.1-1.11.1
Intermitt. access day 1 inactive lever presses0.00.20.90.6-0.4-0.50.40.5-0.30.00.20.90.10.60.5-0.4-0.50.4-0.40.6-0.5-0.50.5
Intermitt. access day 15 inactive lever presses0.21.13.3-0.10.10.1-0.5-0.51.21.1-1.1-0.6-1.3-0.0-1.21.81.4-1.71.7-1.30.60.6-0.6
Intermitt. access escalation Index0.41.12.11.1-1.1-1.11.11.1-1.1-1.41.10.61.11.41.0-0.9-1.40.9-0.90.9-0.9-0.90.8
Intermittent access day 1 total infusions0.20.73.01.2-1.3-1.20.80.7-0.0-0.1-0.30.1-0.31.7-0.41.30.2-1.11.1-0.60.20.2-0.2
Intermittent access day 15 total infusions1.43.38.22.6-2.5-2.52.22.3-1.6-1.21.32.11.32.91.5-0.7-1.30.9-0.91.4-1.7-1.71.8
Intermittent access terminal intake (last 3 days)0.50.93.51.6-1.6-1.61.21.2-0.5-0.20.21.10.21.90.40.4-0.1-0.30.30.3-0.7-0.70.8
Intermittent access total infusions0.81.04.61.7-1.7-1.71.31.2-0.6-0.50.30.90.32.10.30.5-0.4-0.30.30.2-0.6-0.60.7
Intermittent access day 1 locomotion0.30.51.50.5-0.5-0.50.20.10.30.3-0.6-0.3-0.61.2-0.71.20.2-1.21.2-0.80.50.5-0.5
Intermittent access day 15 total locomotion0.10.51.80.6-0.6-0.60.20.20.50.7-0.70.2-0.70.8-0.71.30.7-1.21.2-0.70.20.2-0.2
Intermittent access total locomotion0.70.93.21.3-1.3-1.20.70.70.30.4-0.60.4-0.61.8-0.61.60.4-1.41.4-0.70.10.10.1
Intermittent access standard deviation0.00.20.70.4-0.3-0.40.40.5-0.40.10.20.80.20.10.5-0.5-0.00.5-0.50.7-0.5-0.50.6
Left kidney weight0.21.23.51.7-1.9-1.81.51.3-0.9-1.51.00.40.91.60.50.2-0.3-0.10.10.1-0.9-0.91.0
Right kidney weight0.10.51.61.2-1.3-1.21.00.9-0.6-0.80.60.20.60.60.30.1-0.2-0.10.10.1-0.4-0.40.5
Cocaine induced anxiety0.00.10.5-0.50.50.5-0.5-0.40.40.7-0.40.0-0.4-0.7-0.10.0-0.0-0.00.00.00.10.1-0.1
Post-drug Anxiety0.30.30.8-0.40.50.5-0.5-0.50.60.9-0.6-0.2-0.6-0.8-0.50.60.6-0.60.6-0.50.40.4-0.4
Baseline Anxiety0.10.20.4-0.10.10.1-0.2-0.30.30.0-0.2-0.7-0.2-0.2-0.50.50.5-0.60.6-0.60.40.4-0.5
Tail length0.10.61.8-1.31.21.2-1.0-1.10.60.3-0.1-1.3-0.2-0.8-0.60.21.1-0.30.3-0.70.60.6-0.6
Length with tail0.94.08.4-2.22.02.0-2.0-2.22.01.3-1.5-2.7-1.5-2.0-2.22.02.9-2.02.0-2.31.61.6-1.5
Length without tail1.57.913.4-2.72.52.6-2.7-2.82.82.5-2.6-3.4-2.5-3.4-2.82.73.7-2.82.8-2.92.62.6-2.5
Times rat made contact with spout0.30.30.8-0.90.90.9-0.8-0.70.60.6-0.4-0.5-0.4-0.6-0.40.00.6-0.10.1-0.20.50.5-0.4
Lifetime Intake0.50.63.11.3-1.3-1.31.00.9-0.4-0.40.10.60.11.80.10.5-0.2-0.40.4-0.0-0.2-0.20.3
Liver weight, left0.61.01.41.0-0.9-1.01.01.1-1.0-0.81.11.21.00.91.1-1.2-0.61.1-1.11.2-0.8-0.80.9
Liver weight, right1.22.13.41.8-1.7-1.81.71.8-1.6-1.01.51.41.50.21.7-1.4-0.51.4-1.41.6-1.2-1.21.3
Locomotor activity0.71.12.40.8-0.8-0.80.91.0-1.4-1.01.30.41.3-0.61.3-1.5-0.41.4-1.41.2-0.6-0.60.8
Locomotor testing distance0.40.91.90.9-0.8-0.90.91.0-1.2-0.51.10.51.0-0.61.3-1.4-0.71.2-1.21.2-0.5-0.50.6
Locomotor testing rearing0.20.91.90.8-0.7-0.80.81.0-1.2-0.20.80.90.8-0.61.3-1.4-0.51.3-1.31.4-0.6-0.60.8
Locomotion in novel chamber1.62.23.31.8-1.8-1.81.71.7-1.5-1.31.31.41.31.41.4-1.1-1.31.2-1.21.3-1.5-1.51.5
Locomotion in novel chamber post-restriction0.51.41.91.0-1.0-1.01.11.2-1.2-1.01.21.41.10.71.3-1.4-1.11.4-1.41.4-1.2-1.21.1
Fecal boli incidents, locomotor time 10.10.20.8-0.00.20.1-0.30.00.10.9-0.10.8-0.2-0.8-0.00.20.9-0.10.10.2-0.4-0.40.4
Change in fecal boli incidents, locomotor task2.02.13.41.7-1.8-1.81.81.6-1.5-1.91.60.71.71.51.4-1.2-1.61.2-1.21.1-1.1-1.11.1
Time >=10cm from walls, locomotor time 10.81.03.31.4-1.3-1.31.11.2-0.8-0.60.61.50.61.80.7-0.2-0.90.4-0.40.8-1.1-1.11.1
Bouts of movement, locomotor time 11.62.15.0-2.12.22.1-2.0-1.71.21.7-1.0-0.6-1.1-2.2-1.10.62.2-0.60.6-0.70.70.7-0.7
Total resting periods, locomotor time 11.21.33.6-1.71.71.7-1.6-1.40.91.5-0.8-0.5-0.8-1.8-0.90.51.9-0.50.5-0.60.40.4-0.4
Rest time, locomotor task time 10.60.91.80.9-0.9-0.90.81.0-1.3-0.81.21.31.10.40.9-0.8-0.30.9-0.91.0-1.1-1.11.1
Distance moved, locomotor task time 10.10.20.50.0-0.0-0.00.1-0.10.50.1-0.6-0.3-0.50.6-0.20.3-0.7-0.30.3-0.30.50.5-0.5
Vertical activity count, locomotor time 10.21.65.31.2-1.2-1.21.41.2-0.9-1.40.90.60.91.91.3-1.3-2.31.2-1.21.1-0.8-0.80.8
Time >=10cm from walls, locomotor time 20.10.30.90.3-0.3-0.30.30.4-0.1-0.10.20.90.20.80.5-0.4-0.80.5-0.50.6-0.8-0.80.8
Bouts of movement, locomotor time 21.75.89.6-2.42.62.5-2.7-2.42.13.0-2.6-1.3-2.6-3.1-2.32.12.7-2.12.1-1.92.32.3-2.3
Total resting periods, locomotor time 21.24.98.5-2.22.42.3-2.5-2.21.82.9-2.4-1.0-2.4-2.9-2.11.92.5-2.02.0-1.72.12.1-2.1
Rest time, locomotor task time 20.40.62.00.9-0.9-0.90.81.0-1.3-0.60.81.40.70.30.8-0.7-0.10.7-0.70.9-0.4-0.40.4
Distance moved, locomotor task time 20.10.11.1-0.30.20.3-0.1-0.20.2-0.2-0.1-0.40.00.70.2-0.4-1.10.4-0.40.1-0.3-0.30.3
Vertical activity count, locomotor time 20.41.03.60.4-0.5-0.40.80.6-0.7-1.30.8-0.10.90.91.1-1.5-1.91.4-1.41.0-0.7-0.70.7
Light reinforcement 10.10.30.80.4-0.3-0.40.30.5-0.20.20.50.70.4-0.20.7-0.6-0.30.6-0.60.8-0.9-0.90.9
Light reinforcement 20.51.02.51.3-1.3-1.31.11.1-0.5-0.81.01.01.01.10.6-0.1-0.70.3-0.30.5-1.6-1.61.5
Bone: marrow area1.23.06.62.5-2.6-2.52.32.1-1.6-2.01.71.81.62.01.1-0.3-1.30.5-0.50.8-1.6-1.61.6
Bone: maximum diameter0.10.20.60.4-0.5-0.50.30.20.1-0.40.1-0.10.10.8-0.20.50.0-0.40.4-0.4-0.6-0.60.6
Bone: maximum force0.91.73.8-0.90.80.9-1.1-1.21.71.1-1.0-1.6-1.3-0.4-1.62.01.0-1.91.9-1.80.90.9-0.9
Bone: maximum moment0.91.73.6-0.90.80.9-1.1-1.21.71.1-1.1-1.6-1.3-0.5-1.61.91.1-1.81.8-1.70.90.9-0.9
Mean time between licks in bursts0.21.02.6-1.01.11.0-1.0-1.00.91.0-1.1-0.9-1.1-0.7-0.90.6-0.1-0.80.8-0.81.61.6-1.5
Mean num. licks in bursts0.10.10.4-0.40.50.4-0.2-0.10.10.5-0.10.0-0.1-0.60.3-0.6-0.30.6-0.60.50.10.1-0.1
Cd content in liver0.91.01.41.0-1.0-1.01.01.1-0.9-0.60.91.00.90.61.1-1.0-1.21.0-1.01.1-1.0-1.01.0
Co content in liver0.80.91.80.4-0.4-0.50.70.7-1.0-1.01.00.81.01.21.1-1.4-1.21.3-1.31.1-0.7-0.70.7
Cu content in liver0.10.10.50.1-0.1-0.10.20.1-0.3-0.70.5-0.10.50.40.2-0.4-0.30.4-0.40.2-0.2-0.20.2
Fe content in liver0.00.00.00.1-0.1-0.10.10.0-0.0-0.10.00.00.00.2-0.10.10.1-0.10.1-0.10.10.1-0.1
K content in liver0.10.10.4-0.0-0.00.0-0.1-0.20.40.1-0.3-0.4-0.30.0-0.40.6-0.0-0.50.6-0.50.30.3-0.2
Mg content in liver0.00.00.30.4-0.3-0.30.20.3-0.00.10.1-0.10.1-0.60.10.10.2-0.10.10.00.10.1-0.1
Mn content in liver2.22.53.3-1.61.51.6-1.6-1.71.81.2-1.7-1.7-1.7-0.8-1.81.80.9-1.71.7-1.81.61.6-1.5
Na content in liver0.10.11.0-0.20.30.3-0.3-0.20.41.0-0.4-0.2-0.4-0.3-0.10.2-0.0-0.20.2-0.00.10.1-0.1
Rb content in liver2.12.53.01.7-1.6-1.61.71.7-1.7-1.41.61.71.61.11.7-1.7-1.51.6-1.61.7-1.4-1.41.4
Se content in liver0.20.20.7-0.30.20.3-0.4-0.40.40.1-0.5-0.2-0.5-0.0-0.70.80.2-0.70.7-0.70.40.4-0.4
Sr content in liver6.05.26.3-2.42.42.4-2.4-2.42.32.2-2.3-2.2-2.3-2.1-2.22.02.1-2.12.1-2.12.52.5-2.5
Zn content in liver2.52.94.0-1.71.71.7-1.8-1.81.81.7-1.7-2.0-1.7-1.2-1.61.51.2-1.51.5-1.71.91.9-1.9
Bone: minimum diameter0.81.63.71.9-1.9-1.91.61.5-1.0-1.21.21.21.11.60.7-0.1-1.10.2-0.20.5-1.3-1.31.3
Time in familiar zone, hab. session 10.00.10.3-0.00.10.0-0.1-0.10.30.4-0.10.0-0.2-0.5-0.10.20.5-0.20.2-0.1-0.1-0.10.1
Time in novel zone, hab. session 11.01.11.61.0-0.9-1.01.01.1-1.2-0.71.01.21.00.91.2-1.2-1.01.2-1.21.2-0.9-0.90.9
Total zone transitions, hab. session 10.30.40.6-0.80.80.8-0.7-0.70.60.6-0.7-0.8-0.5-0.8-0.40.20.4-0.30.3-0.40.70.7-0.6
Total locomotion distance, hab. session 10.10.20.5-0.00.10.1-0.2-0.20.40.5-0.70.0-0.5-0.3-0.50.60.4-0.60.6-0.50.60.6-0.6
Locomotion velocity, hab. session 10.60.81.4-0.70.70.7-0.8-0.80.90.9-1.2-0.6-1.0-0.8-0.90.90.8-1.01.0-0.91.11.1-1.1
Time in familiar zone, hab. session 20.91.01.50.7-0.6-0.70.80.9-0.9-0.61.11.01.00.41.2-1.2-0.91.2-1.21.2-1.2-1.21.2
Time in novel zone, hab. session 20.70.81.2-0.60.60.6-0.7-0.80.90.9-1.0-1.0-0.9-0.6-0.91.00.7-1.01.0-1.01.11.1-1.1
Total zone transitions, hab. session 20.70.91.9-0.91.01.0-1.0-0.91.11.4-1.0-1.1-0.9-1.4-0.70.70.7-0.70.7-0.70.90.9-0.9
Total locomotion distance, hab. session 20.30.51.1-0.40.50.5-0.6-0.50.71.0-0.9-0.3-0.7-1.0-0.50.60.7-0.70.7-0.50.80.8-0.7
Locomotion velocity, hab. session 20.20.20.6-0.10.20.2-0.3-0.30.50.8-0.7-0.1-0.5-0.8-0.40.60.5-0.60.6-0.40.60.6-0.5
Novel to familiar place preference ratio1.11.43.2-1.11.01.0-1.0-1.21.10.4-0.9-1.8-1.0-0.5-1.41.31.0-1.31.4-1.61.21.2-1.2
Novelty place preference0.70.92.0-0.80.70.7-0.8-1.00.80.2-0.7-1.4-0.7-0.3-1.21.10.8-1.11.1-1.31.01.0-1.0
Time in novel zone, NPP test1.11.42.3-1.00.91.0-1.0-1.21.00.5-1.0-1.5-1.0-0.6-1.41.31.2-1.41.4-1.51.31.3-1.3
Total zone transitions, NPP test1.11.62.5-1.41.51.5-1.4-1.31.41.5-1.4-1.3-1.3-1.6-0.90.70.9-0.80.8-0.91.41.4-1.3
Total locomotion distance, NPP test0.10.20.7-0.40.40.4-0.4-0.40.40.5-0.5-0.5-0.3-0.9-0.20.20.2-0.20.2-0.30.60.6-0.5
Locomotion velocity, NPP test0.00.00.2-0.20.20.2-0.1-0.10.10.1-0.1-0.40.1-0.40.1-0.2-0.40.1-0.10.00.10.1-0.1
Intraocular pressure0.00.00.2-0.30.40.3-0.3-0.2-0.00.2-0.10.4-0.1-0.2-0.0-0.10.10.1-0.10.10.10.1-0.1
Delta distance traveled before/after self-admin0.20.20.60.1-0.0-0.00.20.2-0.6-0.50.40.40.40.40.4-0.7-0.80.6-0.60.50.20.2-0.1
Delta ambulatory time before/after self-admin0.20.41.00.2-0.1-0.20.30.4-0.8-0.50.60.60.60.50.7-1.0-1.00.9-0.90.8-0.2-0.20.2
Parametrial fat weight2.66.112.03.2-3.5-3.33.12.7-2.3-3.42.51.72.43.31.6-0.6-1.90.9-0.91.1-2.5-2.52.5
Pavlov. Cond. lever latency0.20.20.60.3-0.3-0.30.40.4-0.7-0.70.70.80.40.50.4-0.6-0.20.5-0.50.5-0.2-0.20.2
Pavlov. Cond. magazine entry latency0.60.71.5-0.60.60.6-0.8-0.71.21.2-1.0-0.5-1.0-0.8-0.91.20.9-1.11.1-0.90.40.4-0.4
Pavlov. Cond. change in total contacts0.20.20.7-0.30.30.3-0.4-0.30.70.8-0.7-0.2-0.6-0.4-0.40.50.2-0.40.4-0.30.00.0-0.0
Pavlov. Cond. index score0.20.30.7-0.50.50.5-0.6-0.50.80.8-0.7-0.5-0.6-0.7-0.50.60.6-0.50.5-0.50.10.1-0.1
Pavlov. Cond. latency score0.10.10.4-0.20.20.2-0.3-0.30.60.6-0.5-0.4-0.3-0.6-0.30.40.4-0.40.4-0.3-0.1-0.10.1
Pavlov. Cond. lever contacts0.00.00.20.0-0.1-0.0-0.0-0.00.30.3-0.2-0.4-0.1-0.3-0.10.3-0.1-0.20.2-0.1-0.2-0.20.2
Pavlov. Cond. magazine entry number0.50.61.30.8-0.8-0.90.90.8-1.2-1.00.90.50.90.60.8-0.8-0.70.7-0.70.7-0.3-0.30.3
Pavlov. Cond. intertrial magazine entries0.10.10.3-0.30.30.3-0.2-0.10.00.4-0.1-0.2-0.0-0.50.4-0.50.10.5-0.50.4-0.0-0.00.1
Pavlov. Cond. lever-magazine prob. diff.0.30.40.8-0.60.60.6-0.7-0.60.90.9-0.8-0.5-0.7-0.7-0.60.70.5-0.60.6-0.50.20.2-0.2
Pavlov. Cond. response bias0.50.61.2-0.70.70.7-0.8-0.81.11.1-1.0-0.6-0.9-0.5-0.80.90.5-0.80.8-0.70.30.3-0.3
Pavlov. Cond. lever latency1.11.52.80.9-0.9-0.91.11.0-1.3-1.71.60.41.50.81.3-1.6-1.61.5-1.51.2-0.9-0.90.9
Pavlov. Cond. magazine entry latency5.68.011.1-2.82.82.8-3.0-2.93.23.3-3.3-2.0-3.3-1.6-3.03.03.0-2.92.9-2.72.52.5-2.5
Pavlov. Cond. change in total contacts1.02.55.5-1.31.41.4-1.6-1.41.92.3-2.2-0.5-2.0-0.8-1.61.82.1-1.71.7-1.31.01.0-0.9
Pavlov. Cond. index score3.45.38.4-2.02.12.0-2.3-2.22.62.8-2.8-1.2-2.7-1.3-2.52.72.9-2.62.6-2.31.81.8-1.8
Pavlov. Cond. latency score3.14.98.2-1.91.91.9-2.2-2.12.52.7-2.7-1.2-2.6-1.3-2.42.72.9-2.62.6-2.21.71.7-1.7
Pavlov. Cond. lever contacts1.21.73.6-1.01.11.1-1.3-1.11.41.9-1.8-0.2-1.6-1.0-1.41.51.9-1.51.5-1.11.01.0-0.9
Pavlov. Cond. magazine entry number9.512.316.13.5-3.5-3.53.73.6-3.9-3.94.02.63.92.03.8-3.7-3.83.7-3.63.5-3.1-3.13.1
Pavlov. Cond. intertrial magazine entries1.22.53.51.5-1.5-1.51.61.7-1.7-1.51.71.41.70.31.9-1.9-1.31.8-1.81.8-1.5-1.51.6
Pavlov. Cond. lever-magazine prob. diff.3.85.99.2-2.12.22.2-2.5-2.32.73.0-3.0-1.3-2.8-1.5-2.62.83.0-2.72.7-2.31.91.9-1.9
Pavlov. Cond. response bias2.94.06.5-1.71.81.8-2.0-1.92.32.5-2.5-1.1-2.4-1.1-2.22.32.2-2.32.3-1.91.71.7-1.6
Time in closed arm before self-admin0.20.41.30.7-0.8-0.70.60.7-0.3-0.20.50.70.51.10.4-0.1-0.30.2-0.20.4-1.0-1.01.0
Time in closed arm after self-admin0.50.60.90.8-0.8-0.80.80.8-1.0-0.71.00.60.90.30.8-0.7-0.00.7-0.70.7-0.8-0.80.8
Time in open arm before self-admin1.01.22.50.8-0.8-0.91.11.0-1.4-1.61.30.21.30.41.2-1.6-1.21.4-1.41.1-0.3-0.30.3
Time in open arm after self-admin0.30.40.8-0.90.80.8-0.7-0.70.50.2-0.6-0.8-0.5-0.2-0.40.1-0.3-0.20.2-0.50.90.9-0.9
Bone: periosteal estimation0.30.71.81.2-1.3-1.21.00.9-0.4-0.90.80.50.61.30.20.3-0.6-0.20.20.0-1.0-1.01.0
Bone: periosteal perimeter0.20.30.80.9-0.9-0.80.70.7-0.2-0.30.40.40.40.50.30.1-0.1-0.10.10.2-0.8-0.80.8
Bone: post-yield work0.61.02.91.6-1.7-1.61.31.1-0.5-1.10.80.70.81.00.20.6-0.3-0.40.4-0.1-1.2-1.21.2
Progressive ratio test 1 active lever presses0.10.11.30.5-0.5-0.50.40.4-0.2-0.20.10.30.11.10.10.2-0.2-0.10.10.0-0.1-0.10.1
Progressive ratio test 1 breakpoint0.10.11.20.5-0.5-0.50.40.4-0.2-0.10.10.30.11.10.00.2-0.1-0.20.2-0.0-0.1-0.10.1
Progressive ratio test 1 inactive lever presses0.92.43.9-1.01.01.0-1.3-1.31.61.5-1.7-1.3-1.8-1.1-1.82.01.5-2.02.0-1.81.51.5-1.5
Progressive ratio test 2 active lever presses0.40.61.91.3-1.2-1.21.01.0-0.5-0.30.41.00.51.40.40.1-0.40.0-0.00.4-0.7-0.70.7
Progressive ratio test 2 breakpoint0.40.61.81.3-1.2-1.21.01.0-0.5-0.30.30.90.41.30.40.2-0.3-0.10.10.3-0.7-0.70.7
Progressive ratio test 2 inactive lever presses0.10.41.41.0-1.0-1.00.70.7-0.10.10.10.7-0.01.20.10.50.0-0.40.40.1-0.5-0.50.5
Incentive Sensitization - Responses0.20.61.9-0.20.20.2-0.4-0.50.90.9-1.0-0.3-0.9-0.3-1.01.40.7-1.31.3-1.00.60.6-0.6
Incentive Sensitization - Breakpoint0.20.51.80.0-0.0-0.0-0.3-0.30.80.8-0.8-0.2-0.8-0.1-0.91.30.6-1.21.2-0.90.50.5-0.5
Sum of active levers in priming session hrs 5-60.50.51.1-1.01.01.0-1.0-0.90.90.8-0.9-0.4-1.0-0.4-0.60.40.4-0.30.3-0.40.40.4-0.4
Progressive ratio0.00.10.60.4-0.5-0.40.20.20.1-0.0-0.10.1-0.10.8-0.30.70.0-0.60.6-0.4-0.2-0.20.1
Food seeking constrained by brief footshock0.10.10.50.2-0.1-0.20.10.2-0.20.10.20.30.20.70.2-0.2-0.50.1-0.10.3-0.1-0.10.1
Seeking ratio, punishment vs. effort0.00.10.3-0.30.30.3-0.2-0.2-0.10.10.0-0.20.0-0.50.1-0.3-0.00.2-0.20.10.60.6-0.4
Retroperitoneal fat weight2.712.221.84.6-4.7-4.64.44.2-3.8-4.23.73.33.62.53.1-2.1-2.22.3-2.32.6-3.2-3.23.2
Reaction time number correct0.10.42.3-0.70.70.6-0.6-0.50.50.8-0.0-0.7-0.2-1.3-0.20.01.5-0.10.1-0.10.20.2-0.0
Reaction time mean minus median0.10.81.4-1.11.21.2-1.1-1.01.01.2-1.1-0.6-1.0-1.1-0.70.50.7-0.50.5-0.60.60.6-0.8
Reaction time mean minus median AUC0.10.61.8-1.11.21.1-1.0-0.80.71.1-0.8-0.2-0.7-1.3-0.3-0.10.70.0-0.0-0.10.40.4-0.5
Reaction time num false alarms0.20.30.90.2-0.3-0.30.40.4-0.7-0.80.90.10.70.50.7-0.9-0.60.8-0.80.6-0.2-0.20.1
Reaction time num false alarms AUC0.10.20.6-0.30.20.20.0-0.1-0.4-0.60.6-0.60.40.20.3-0.8-0.50.6-0.60.20.20.2-0.2
Reaction time trials correct on left0.10.42.3-0.70.70.6-0.6-0.50.50.8-0.0-0.7-0.2-1.3-0.20.01.5-0.10.1-0.10.20.2-0.0
Reaction time trials on left0.10.42.4-0.70.70.7-0.6-0.60.50.8-0.1-0.7-0.2-1.4-0.20.01.6-0.10.1-0.10.20.2-0.0
Reaction time mean0.10.21.1-0.40.60.5-0.5-0.40.61.0-0.90.3-0.7-0.1-0.10.1-0.2-0.10.00.10.20.2-0.4
Reaction time mean AUC0.10.10.7-0.10.30.2-0.2-0.10.30.9-0.60.6-0.40.10.1-0.1-0.40.1-0.20.4-0.1-0.1-0.1
Median of all reaction times0.10.20.8-0.30.40.4-0.4-0.30.50.9-0.80.3-0.60.3-0.20.2-0.3-0.20.2-0.00.20.2-0.4
Reaction time omissions0.20.40.9-0.90.90.9-0.8-0.80.60.6-0.7-0.5-0.6-0.9-0.40.20.7-0.20.2-0.30.40.4-0.5
Reaction time false alarm rate0.20.31.50.3-0.4-0.30.50.4-0.7-1.00.6-0.00.61.00.5-0.7-1.20.6-0.60.3-0.1-0.1-0.0
Reaction time premature initiation rate1.93.05.8-1.41.11.2-1.4-1.71.70.9-1.7-2.4-1.60.0-2.12.31.2-2.22.2-2.41.71.7-1.7
Reaction time premature initiations1.23.77.5-1.91.71.8-1.9-2.12.01.4-1.7-2.7-1.7-1.0-2.22.12.1-2.12.1-2.31.81.8-1.7
Std. dev. reaction times0.00.20.4-0.60.70.6-0.5-0.30.30.6-0.50.2-0.3-0.40.1-0.4-0.20.4-0.40.30.00.0-0.2
Reaction time trials completed0.10.42.4-0.70.70.7-0.6-0.60.50.8-0.1-0.7-0.2-1.4-0.20.01.6-0.10.1-0.10.20.2-0.0
Reaction time trials AUC0.10.42.4-0.60.60.6-0.5-0.50.40.8-0.0-0.6-0.2-1.4-0.2-0.01.6-0.10.1-0.10.20.2-0.0
Run reversals in cocaine runway, females0.20.20.90.2-0.3-0.20.1-0.10.1-0.3-0.2-0.9-0.30.1-0.50.70.2-0.70.7-0.70.60.6-0.5
Run reversals in cocaine runway, males1.61.83.91.1-1.2-1.11.31.2-1.4-1.61.40.51.41.61.4-1.5-2.01.5-1.51.2-1.1-1.11.3
Latency to leave start box in cocaine runway0.91.22.51.5-1.6-1.51.41.2-0.8-1.31.10.51.11.50.7-0.2-0.80.3-0.30.4-1.2-1.21.1
Latency to leave start box in cocaine runway, F0.10.10.20.3-0.4-0.40.20.20.0-0.30.2-0.30.10.4-0.20.40.1-0.40.4-0.3-0.2-0.20.1
Latency to leave start box in cocaine runway, M3.02.83.81.9-2.0-1.91.91.8-1.6-1.91.81.51.81.81.5-1.2-1.61.3-1.31.4-1.8-1.81.7
Std. dev. time between licks in bursts0.10.31.00.5-0.5-0.50.50.5-0.6-0.50.50.20.50.60.5-0.5-1.00.5-0.50.5-0.2-0.20.3
Total sessions with >9 infusions0.10.11.00.5-0.4-0.40.30.3-0.3-0.0-0.00.4-0.11.00.00.1-0.4-0.10.10.10.10.1-0.1
Short access day 1 total inactive lever presses0.00.10.40.3-0.4-0.30.20.2-0.0-0.20.1-0.20.10.6-0.10.3-0.2-0.30.3-0.20.10.1-0.1
Short access day 10 total inactive lever presses0.00.10.40.10.0-0.00.10.2-0.30.10.10.6-0.00.30.4-0.6-0.60.5-0.50.6-0.1-0.10.1
Short access day 1 total infusions0.30.71.91.1-1.1-1.11.01.0-0.9-0.80.70.70.71.40.7-0.5-0.70.5-0.50.7-0.6-0.60.6
Short access day 10 total infusions0.30.42.90.9-0.9-0.90.60.50.00.0-0.30.2-0.31.7-0.30.9-0.1-0.90.9-0.40.20.2-0.2
Short access total infusions0.20.31.90.9-0.9-0.90.70.6-0.3-0.30.10.20.01.4-0.00.4-0.2-0.40.4-0.10.10.1-0.1
Short access day 1 locomotion0.10.11.00.3-0.4-0.40.30.3-0.2-0.30.20.10.21.00.10.0-0.30.0-0.00.1-0.2-0.20.2
Short access day 10 total locomotion0.20.82.40.1-0.0-0.1-0.3-0.30.81.0-1.1-0.0-1.10.4-1.01.50.6-1.51.5-1.00.90.9-0.8
Short access total locomotion0.20.31.10.3-0.3-0.30.0-0.00.40.5-0.60.0-0.70.8-0.61.10.3-1.01.0-0.60.50.5-0.4
One hour access (0.3 mA shock)0.70.92.21.5-1.5-1.51.21.2-0.7-0.70.61.10.71.50.50.1-0.50.0-0.00.4-0.8-0.80.8
Compulsive drug intake0.91.45.6-1.51.61.5-1.3-1.30.70.9-0.9-0.9-0.8-2.4-0.80.31.1-0.40.4-0.71.31.3-1.3
One hour access (shock baseline)1.64.110.32.6-2.7-2.62.42.4-1.7-1.71.72.01.83.21.7-0.9-1.71.1-1.11.5-2.1-2.12.1
Social response proportion0.50.61.20.6-0.7-0.70.70.6-0.7-0.91.00.10.90.60.7-0.7-0.80.7-0.70.6-1.1-1.11.1
Social responses0.30.41.00.0-0.1-0.10.30.3-0.7-0.70.8-0.00.70.30.7-1.0-0.61.0-1.00.7-0.9-0.90.9
Social time0.10.20.7-0.60.60.5-0.3-0.2-0.30.20.1-0.00.2-0.80.4-0.8-0.20.7-0.70.5-0.1-0.10.1
Soleus weight2.77.89.92.8-2.7-2.82.83.0-3.0-2.22.53.12.62.33.1-2.9-2.62.9-2.93.1-2.7-2.72.8
Bone: stiffness0.10.10.5-0.10.00.1-0.2-0.30.50.1-0.1-0.4-0.30.4-0.50.70.2-0.60.6-0.6-0.2-0.20.2
Tibialis anterior weight8.428.835.7-5.75.65.6-5.7-5.85.55.0-5.4-6.0-5.5-4.9-5.34.74.9-4.94.9-5.35.55.5-5.5
Time to tail flick, vehicle, before self-admin0.20.20.70.1-0.1-0.1-0.1-0.10.30.1-0.3-0.4-0.40.6-0.50.80.1-0.80.8-0.60.20.2-0.2
Time to tail flick, vehicle, after self-admin0.51.01.8-0.60.60.6-0.8-0.80.90.8-0.9-0.9-0.9-0.8-1.11.31.3-1.31.3-1.21.01.0-0.9
Time to tail flick, test, before self-admin0.10.20.50.3-0.4-0.30.20.1-0.1-0.40.1-0.7-0.00.0-0.40.60.5-0.60.6-0.60.30.3-0.4
Time to tail flick, test, after self-admin0.00.00.10.00.00.00.00.1-0.10.10.10.4-0.10.20.2-0.2-0.20.3-0.30.3-0.3-0.30.3
Delta time to tail flick, vehicle, before/after SA0.70.71.8-0.90.90.9-0.9-0.90.80.9-0.7-0.7-0.6-1.3-0.80.61.3-0.70.7-0.70.80.8-0.8
Delta time to tail flick, test, before/after SA0.20.20.8-0.80.90.8-0.7-0.50.40.7-0.50.5-0.4-0.30.1-0.4-0.30.4-0.40.4-0.1-0.10.1
Tibia length0.71.83.0-1.31.21.2-1.3-1.41.61.1-1.3-1.7-1.4-0.9-1.51.71.5-1.61.6-1.60.90.9-0.7
Ambulatory time before self-admin0.31.01.6-0.90.80.9-1.0-1.01.31.3-1.2-0.7-1.2-0.7-1.11.31.2-1.21.2-1.00.50.5-0.5
Ambulatory time after self-admin0.10.10.3-0.20.20.2-0.3-0.20.30.5-0.40.1-0.40.2-0.30.50.4-0.40.4-0.30.00.00.0
Bone: tissue strength0.80.81.20.9-0.8-0.90.90.9-0.9-0.71.10.90.90.71.0-1.0-1.01.0-1.01.0-0.9-0.90.9
Total heroin consumption5.16.09.7-3.13.03.1-2.9-2.92.52.1-2.4-2.6-2.4-2.8-2.31.61.8-1.71.7-2.22.32.3-2.4
Bone: trabecular number0.50.91.9-0.60.50.6-0.7-0.80.90.6-1.0-1.2-1.0-0.2-1.21.40.8-1.31.3-1.30.90.9-0.9
Bone: trabecular spacing0.30.41.40.10.10.00.10.3-0.40.40.40.80.4-0.20.9-1.2-0.41.1-1.11.1-0.4-0.40.4
Bone: trabecular thickness0.30.40.80.8-0.9-0.80.80.7-0.7-0.80.80.60.60.60.5-0.30.10.4-0.40.4-0.8-0.80.8
Bone: trabecular tissue density3.15.56.82.1-2.1-2.12.32.4-2.5-2.22.52.62.41.72.5-2.5-2.22.6-2.62.6-2.3-2.32.3
Water consumed over 24 hours0.10.30.6-0.80.60.7-0.6-0.70.50.1-0.3-0.7-0.30.3-0.60.40.7-0.40.4-0.60.30.3-0.2
Number of responses in last shaping day0.50.71.2-1.11.01.0-0.9-1.00.70.5-0.7-1.1-0.7-0.7-0.80.50.4-0.60.6-0.81.01.0-1.0