Hub : Genes

Saxo4

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL mRNA stability Saxo4 0.16 0.11 2.8e-03 0 0.04 0.03 0.01 2.9e-01 3.2e-02 7.1e-02 1.6e-01
2 Brain gene expression Saxo4 0.03 0.02 7.0e-04 0.01 0.03 0.03 0.02 7.2e-02 5.0e-04 1.1e-03 2.7e-03
3 BLA mRNA stability Saxo4 0.04 0.03 8.7e-03 0.01 0.04 0.02 0.02 5.7e-02 4.3e-03 2.3e-02 2.8e-02
4 PL isoform ratio NM_145786.1 0.02 0.01 4.3e-03 0.01 0.02 0 0.01 1.9e-02 6.3e-03 8.2e-02 2.0e-02
5 NAcc gene expression Saxo4 0.02 0.01 1.8e-03 0.01 0.02 0.01 0.01 1.9e-03 6.6e-04 5.3e-03 3.4e-03
6 PL isoform ratio XM_006231016.5 0.05 0.03 4.1e-07 0.05 0.06 0.05 0.05 4.8e-06 6.9e-07 3.7e-06 7.6e-06
7 NAcc mRNA stability Saxo4 0.08 0.04 4.5e-14 0.1 0.1 0.09 0.1 1.6e-14 4.4e-15 8.4e-14 4.2e-15
8 PL mRNA stability Saxo4 0.12 0.08 3.9e-08 0.07 0.07 0.07 0.07 3.6e-08 1.3e-08 8.3e-08 3.5e-08
9 Brain mRNA stability Saxo4 0.13 0.06 4.3e-15 0.16 0.15 0.15 0.15 1.6e-14 3.9e-14 9.5e-14 3.6e-14
10 NAcc intron excision ratio chr1_216543190_216543687 0.01 0.01 7.2e-03 0.01 0.01 0.01 0.01 6.4e-03 1.9e-02 2.1e-02 1.6e-02
11 LHb mRNA stability Saxo4 0.25 0.14 4.2e-04 0.1 0.09 0.1 0.08 2.1e-03 3.9e-03 3.0e-03 5.0e-03
12 OFC gene expression Saxo4 0.22 0.13 8.7e-04 0.04 0.04 0.03 0.02 4.0e-02 3.4e-02 8.1e-02 1.1e-01
13 Adipose mRNA stability Saxo4 0.04 0.03 7.4e-04 0.01 0.02 0.01 0.01 6.6e-02 2.6e-03 1.7e-02 1.2e-02
14 IC isoform ratio XM_006231016.5 0.13 0.08 2.2e-04 0.09 0.05 0.07 0.07 1.6e-04 4.5e-03 6.0e-04 6.4e-04
15 IC alternative TSS XM_006231016.5 0.07 0.05 8.9e-03 0.02 0.03 0.02 0.03 4.8e-02 1.7e-02 4.2e-02 2.5e-02
16 IC alternative TSS XM_063281660.1 0.07 0.05 8.9e-03 0.01 0.03 0.02 0.03 1.0e-01 1.6e-02 4.2e-02 2.6e-02
17 NAcc isoform ratio XM_006231016.5 0.02 0.02 2.7e-03 0.01 0.01 0 0.01 1.3e-02 3.4e-03 4.4e-02 1.6e-02
18 BLA isoform ratio XM_006231016.5 0.09 0.07 1.4e-03 0.04 0.03 0.03 0.03 2.4e-03 1.3e-02 8.5e-03 1.2e-02
19 pVTA isoform ratio XM_006231016.5 0.08 0.1 2.5e-03 0.01 -0 -0 -0 4.4e-02 7.5e-01 6.5e-01 6.9e-01
20 PL intron excision ratio chr1_216543815_216545639 0.03 0.02 4.1e-03 0.01 0 -0 0 1.5e-02 1.2e-01 8.5e-01 7.9e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.10.10.5-0.1-0.0-0.00.0-0.1-0.20.30.20.20.60.3-0.50.7-0.4-0.60.6-0.6-0.2-0.20.2
Area under the delay curve0.10.10.4-0.50.3-0.4-0.30.30.1-0.0-0.6-0.30.5-0.3-0.10.30.5-0.30.3-0.4-0.0-0.00.0
BMI with tail3.110.718.11.8-2.02.02.1-2.6-2.73.23.03.43.23.5-3.74.2-3.4-4.34.3-3.8-3.6-3.63.5
BMI without tail0.82.33.90.8-1.11.01.1-1.2-1.31.40.91.31.71.4-1.71.8-1.5-1.81.8-1.8-2.0-2.02.0
Body weight3.214.020.62.5-2.92.82.9-3.2-3.53.72.93.54.43.5-4.34.5-4.2-4.54.5-4.5-3.8-3.83.7
Weight adjusted by age2.33.55.01.8-1.71.91.8-1.9-1.81.92.22.21.22.2-1.81.7-1.7-1.81.8-1.6-2.0-2.02.0
Bone surface0.61.12.70.5-0.70.60.7-0.8-1.01.30.70.81.61.0-1.31.6-0.9-1.51.5-1.5-0.6-0.60.6
Bone volume0.20.31.2-0.0-0.10.00.1-0.3-0.40.70.30.40.90.5-0.71.1-0.8-1.01.0-0.9-0.1-0.10.0
Breakpoint value in progressive ratio session2.73.35.02.2-2.22.22.2-2.1-2.11.81.81.81.81.7-1.71.3-1.6-1.31.3-1.5-1.6-1.61.6
Number of licking bursts0.00.10.3-0.1-0.1-0.00.0-0.1-0.10.1-0.30.00.00.0-0.40.4-0.5-0.40.4-0.4-0.1-0.10.1
Context. condit. distance diff. score0.00.00.1-0.10.0-0.0-0.10.0-0.0-0.00.00.2-0.10.2-0.20.2-0.3-0.30.3-0.2-0.3-0.30.3
Locomotion velocity, session 10.30.31.40.6-0.30.50.4-0.5-0.30.51.20.60.20.6-0.10.10.3-0.20.2-0.0-0.7-0.70.7
Locomotion distance, session 11.41.73.21.3-1.11.21.2-1.3-1.21.41.81.61.01.5-1.11.1-1.1-1.21.2-1.0-1.6-1.61.6
Locomotion velocity, session 22.83.34.01.6-1.61.61.7-1.8-1.82.01.71.91.81.9-1.91.9-1.3-1.91.9-1.9-1.9-1.91.9
Locomotion distance, session 21.21.73.11.3-1.21.31.2-1.3-1.21.21.41.40.81.4-1.10.9-1.3-1.01.0-1.0-1.8-1.81.7
Locomotion velocity, session 30.60.72.0-0.2-0.1-0.00.0-0.2-0.40.60.20.60.70.6-1.11.4-0.9-1.41.4-1.2-0.8-0.80.8
Locomotion distance, session 30.30.30.6-0.60.5-0.6-0.60.60.5-0.5-0.8-0.70.1-0.70.4-0.40.80.4-0.40.30.70.7-0.7
Stereotopy head waving bouts, day 30.20.20.5-0.40.4-0.3-0.30.20.10.10.10.30.20.2-0.40.6-0.2-0.70.7-0.5-0.7-0.70.7
Stereotopy head waving duration, day 30.30.41.1-0.1-0.10.10.1-0.2-0.30.30.10.50.40.5-0.70.8-0.4-0.90.9-0.8-1.0-1.01.0
Locomotion velocity, session 70.10.10.5-0.50.3-0.4-0.30.30.1-0.1-0.6-0.20.2-0.2-0.10.20.7-0.20.2-0.30.10.1-0.1
Locomotion distance, session 70.10.10.4-0.50.3-0.3-0.30.30.2-0.2-0.6-0.20.2-0.2-0.10.10.6-0.20.2-0.2-0.2-0.20.2
Stereotopy head waving bouts, day 70.10.20.40.3-0.30.30.3-0.4-0.30.50.60.60.40.5-0.40.5-0.3-0.50.5-0.4-0.3-0.30.2
Stereotopy head waving duration, day 70.91.12.10.9-1.00.91.0-1.0-1.11.20.91.01.41.0-1.11.1-1.0-1.11.1-1.1-0.9-0.90.8
Locomotion velocity, session 80.10.10.30.1-0.20.10.10.1-0.0-0.1-0.4-0.30.3-0.30.3-0.5-0.40.5-0.50.2-0.0-0.00.0
Locomotion distance, session 80.10.10.4-0.10.1-0.1-0.1-0.0-0.00.10.20.4-0.10.3-0.30.4-0.3-0.40.4-0.3-0.6-0.60.6
Degree of sensitization distance0.90.91.90.3-0.30.40.4-0.6-0.60.80.81.00.31.1-1.01.2-0.8-1.31.3-1.1-1.4-1.41.4
Degree of sensitization stereotypy0.90.91.30.9-0.90.90.9-1.0-1.01.21.11.11.01.1-1.01.0-1.0-1.01.0-0.9-0.7-0.70.7
Conditioned locomotion0.60.61.10.7-0.80.80.8-0.8-0.90.80.50.60.90.6-0.90.80.0-0.90.9-0.9-0.8-0.81.0
Cocaine response after cond. corrected0.10.10.70.20.00.20.1-0.2-0.0-0.00.70.4-0.50.4-0.10.1-0.1-0.30.20.0-0.7-0.70.8
Cocaine response after cond. not corrected0.10.10.90.10.20.1-0.0-0.10.10.00.90.4-0.70.50.10.10.2-0.10.10.2-0.4-0.40.4
Cocaine response before conditioning0.10.20.90.2-0.00.10.0-0.10.10.30.70.3-0.20.30.3-0.10.10.2-0.20.40.70.7-0.9
Saline control response1.92.63.61.9-1.91.81.8-1.8-1.81.71.61.41.91.5-1.51.2-1.8-1.31.3-1.5-1.4-1.41.3
Bone: connectivity density0.91.32.40.8-0.90.80.9-1.0-1.11.31.01.11.61.2-1.31.5-0.8-1.51.5-1.4-1.1-1.11.1
Bone: cortical apparent density0.20.30.60.8-0.80.80.8-0.7-0.70.50.40.60.50.5-0.40.2-0.1-0.10.2-0.3-0.4-0.40.4
Bone: cortical area0.10.10.60.3-0.30.30.3-0.3-0.40.60.40.10.80.3-0.30.5-0.1-0.40.4-0.40.20.2-0.2
Bone: cortical porosity0.10.10.50.6-0.70.60.6-0.5-0.50.2-0.00.00.30.1-0.1-0.2-0.40.2-0.2-0.1-0.3-0.30.3
Bone: cortical porosity0.20.30.70.8-0.80.80.8-0.6-0.70.40.20.20.60.4-0.3-0.0-0.4-0.00.0-0.2-0.5-0.50.5
Bone: cortical thickness1.62.75.32.3-2.22.22.2-2.0-2.01.71.71.32.21.4-1.20.8-1.0-0.80.8-1.2-1.3-1.31.2
Bone: cortical thickness0.10.10.40.5-0.50.50.5-0.3-0.40.20.10.10.50.1-0.1-0.10.70.1-0.1-0.0-0.0-0.0-0.0
Bone: cortical tissue density0.40.51.01.0-1.01.01.0-0.9-0.90.70.60.80.70.7-0.60.3-0.2-0.30.3-0.5-0.6-0.60.6
Condit. Reinf. active minus inactive responses1.82.04.91.6-1.31.51.4-1.5-1.31.62.21.70.81.6-1.21.1-1.4-1.21.2-0.9-1.3-1.31.3
Condit. Reinf. active-inactive response ratio1.51.64.41.7-1.41.61.5-1.5-1.21.32.11.30.51.4-0.80.6-1.1-0.70.7-0.5-1.3-1.31.3
Condit. Reinf. active responses1.61.94.61.3-1.11.21.2-1.4-1.21.62.11.80.71.7-1.31.4-1.4-1.51.4-1.1-1.3-1.31.3
Condit. Reinf. inactive responses0.10.10.4-0.40.4-0.3-0.30.10.10.20.30.4-0.30.3-0.30.7-0.4-0.60.6-0.3-0.0-0.00.0
Incentive salience index mean1.01.33.11.1-0.91.00.9-1.1-1.01.41.81.40.81.3-1.01.2-1.0-1.21.2-0.9-1.0-1.01.0
Condit. Reinf. lever presses0.10.20.60.0-0.10.00.0-0.2-0.20.70.50.50.60.4-0.50.8-0.1-0.70.7-0.6-0.1-0.10.0
Condit. Reinf. active minus inactive responses0.10.10.70.3-0.00.20.1-0.2-0.00.20.80.3-0.70.20.00.10.1-0.00.00.20.20.2-0.2
Condit. Reinf. active-inactive response ratio0.20.20.7-0.20.2-0.1-0.1-0.1-0.00.30.40.5-0.80.5-0.50.8-0.6-0.70.7-0.4-0.2-0.20.3
Condit. Reinf. active responses0.10.10.80.5-0.30.40.4-0.4-0.30.40.90.5-0.20.4-0.10.2-0.0-0.20.20.00.00.0-0.1
Condit. Reinf. inactive responses0.20.30.70.20.1-0.0-0.10.20.3-0.30.2-0.40.1-0.50.8-0.90.80.8-0.80.80.70.7-0.9
Condit. Reinf. lever presses0.71.02.00.7-0.70.70.7-0.9-0.91.11.21.30.51.2-1.11.4-1.3-1.31.3-1.1-0.7-0.70.5
Condit. Reinf. lever reinforcers received0.30.41.60.9-0.70.80.7-0.8-0.60.81.30.9-0.00.8-0.50.5-0.5-0.50.5-0.3-0.3-0.30.2
Conditioned reinforcement - actives0.10.20.70.10.1-0.0-0.10.10.2-0.10.5-0.0-0.9-0.10.4-0.30.40.4-0.40.60.60.6-0.6
Conditioned reinforcement - inactives0.10.10.4-0.30.3-0.3-0.30.10.10.20.40.4-0.30.4-0.30.7-0.4-0.60.6-0.30.10.1-0.1
Conditioned locomotion1.41.83.4-1.81.8-1.8-1.81.71.6-1.3-1.1-1.2-1.4-1.21.1-0.61.30.7-0.71.01.21.2-1.2
Patch foraging indifference point 0 sec0.20.51.50.6-0.70.60.7-0.7-0.70.60.40.61.20.6-0.60.6-0.7-0.60.6-0.7-0.8-0.80.5
Patch foraging indifference point AUC0.60.91.61.2-1.21.21.2-1.2-1.11.21.01.01.11.0-0.80.7-0.8-0.70.7-0.8-0.6-0.60.6
Delay disc. indifference point, 0s delay0.20.20.5-0.70.6-0.7-0.60.40.4-0.3-0.2-0.3-0.2-0.3-0.10.50.2-0.50.5-0.3-0.1-0.10.1
Delay disc. indifference point, 16s delay0.00.00.1-0.10.1-0.1-0.10.0-0.10.3-0.00.20.20.2-0.20.40.1-0.30.3-0.3-0.1-0.10.1
Delay disc. indifference point, 2s delay0.70.71.7-1.31.2-1.3-1.21.11.0-0.7-0.9-0.8-0.5-0.80.6-0.10.80.2-0.20.40.90.9-0.9
Delay disc. indifference point, 24s delay0.00.00.2-0.30.2-0.2-0.20.20.10.1-0.4-0.20.3-0.2-0.00.10.5-0.10.1-0.1-0.0-0.00.0
Delay disc. indifference point, 4s delay0.20.21.0-0.40.1-0.3-0.20.2-0.10.0-0.7-0.21.0-0.2-0.40.60.2-0.50.5-0.7-0.4-0.40.4
Delay disc. indifference point, 8s delay0.50.62.2-0.90.7-0.8-0.70.80.6-0.9-1.5-0.90.0-0.90.5-0.51.20.5-0.50.30.40.4-0.4
Indifference point function ln k1.42.54.3-2.12.1-2.0-2.11.91.9-1.8-1.4-1.5-1.9-1.41.4-1.01.31.0-1.01.41.01.0-1.2
Indifference point function log k1.42.54.3-2.12.1-2.0-2.11.91.9-1.8-1.4-1.5-1.9-1.41.4-1.01.31.0-1.01.41.01.0-1.2
Patch foraging total patch changes 0 sec0.20.51.40.8-0.80.80.8-0.7-0.80.50.50.61.20.6-0.60.4-0.6-0.40.4-0.6-0.8-0.80.5
Patch foraging total patch changes 12 sec5.26.89.32.9-3.02.93.0-2.9-2.92.62.32.63.02.5-2.52.1-2.3-2.12.1-2.5-2.5-2.52.4
Patch foraging total patch changes 18 sec0.40.61.31.1-1.01.01.0-1.0-0.90.91.00.70.80.6-0.50.4-1.0-0.40.4-0.5-0.5-0.50.4
Patch foraging total patch changes 24 sec3.96.69.42.3-2.62.42.5-2.6-2.72.62.02.33.12.3-2.82.7-2.7-2.72.7-2.9-2.5-2.52.5
Patch foraging total patch changes 6 sec0.50.72.00.7-0.90.70.8-0.8-0.90.80.40.71.40.7-0.90.9-1.2-0.80.9-1.0-0.8-0.80.6
Patch foraging time to switch 0 sec0.20.41.10.1-0.20.20.2-0.4-0.40.70.40.70.40.6-0.81.0-0.5-1.01.0-0.8-0.3-0.30.5
Patch foraging water rate 0 sec0.51.11.9-0.70.8-0.8-0.80.91.0-1.3-0.8-1.0-0.9-0.91.3-1.41.01.4-1.41.30.90.9-1.1
Patch foraging water rate 12 sec0.91.93.4-1.41.4-1.4-1.41.51.5-1.8-1.3-1.4-1.4-1.31.5-1.50.71.4-1.41.51.01.0-1.0
Patch foraging water rate 18 sec0.60.91.4-1.11.0-1.1-1.11.11.0-1.2-1.1-1.1-0.5-1.00.9-0.91.10.8-0.80.80.70.7-0.8
Patch foraging water rate 24 sec1.11.52.5-1.21.1-1.1-1.21.31.2-1.6-1.2-1.3-1.3-1.21.3-1.30.91.3-1.31.31.11.1-1.2
Patch foraging water rate 6 sec1.01.42.3-1.11.0-1.1-1.11.21.2-1.5-1.3-1.4-0.9-1.31.3-1.40.91.4-1.41.20.90.9-1.0
Seeking ratio, delayed vs. immediate footshock0.20.20.8-0.1-0.0-0.00.0-0.1-0.20.2-0.00.20.10.2-0.60.8-0.9-0.70.7-0.7-0.4-0.40.5
Distance traveled before self-admin1.31.73.11.1-1.11.11.1-1.3-1.31.51.51.41.01.4-1.41.6-1.8-1.51.5-1.4-0.9-0.90.8
Distance traveled after self-admin0.40.50.80.9-0.90.90.9-0.9-0.80.70.90.70.40.8-0.70.6-0.8-0.60.6-0.6-0.6-0.60.5
Extensor digitorum longus weight5.923.327.44.2-4.64.54.6-4.8-5.05.04.24.75.14.9-5.25.0-4.4-5.15.1-5.2-5.0-5.04.9
Bone: elastic displacement0.20.31.20.20.00.10.00.20.3-0.5-0.1-0.4-0.3-0.40.7-1.10.71.0-1.00.80.10.1-0.1
Bone: elastic work0.70.91.81.3-1.31.31.3-1.1-1.10.91.00.61.30.7-0.70.3-0.9-0.40.4-0.6-1.0-1.01.0
Bone: endosteal estimation1.22.66.7-2.62.3-2.4-2.32.11.9-1.4-1.8-1.5-1.6-1.40.9-0.21.20.3-0.30.71.51.5-1.5
Bone: endosteal perimeter1.94.19.4-3.12.8-2.9-2.82.52.4-1.7-2.2-1.8-2.1-1.81.2-0.41.30.6-0.61.02.02.0-2.0
Epididymis fat weight0.72.35.6-2.42.3-2.3-2.32.01.9-1.4-1.5-1.3-1.5-1.21.0-0.2-0.00.4-0.40.81.41.4-1.5
Delta time in closed arm before/after self-admin2.92.74.11.6-1.81.71.7-1.7-1.81.21.11.22.01.3-1.71.3-1.8-1.51.5-1.7-2.0-2.02.0
Delta time in open arm before/after self-admin1.81.82.81.4-1.41.41.4-1.5-1.41.71.51.60.91.6-1.41.4-0.6-1.31.3-1.2-1.1-1.11.1
Diff in mean of infusions in LGA sessions2.73.24.42.0-2.12.12.1-2.1-2.11.71.61.62.01.6-1.81.5-1.5-1.51.5-1.8-1.7-1.71.7
Delay discount exponential model param0.10.10.40.5-0.30.50.4-0.3-0.20.00.70.3-0.50.30.1-0.3-0.60.3-0.30.4-0.0-0.00.0
Extinction: sum of active levers before priming2.83.14.21.5-1.71.61.7-1.7-1.81.91.21.92.01.9-1.91.8-1.2-1.81.8-2.0-1.9-1.91.8
Active lever presses in extinction session 61.91.92.91.5-1.51.51.5-1.5-1.51.61.41.61.21.7-1.41.3-1.2-1.21.2-1.3-1.1-1.11.1
Bone: final force0.60.91.50.8-0.80.80.8-0.9-1.01.21.00.81.21.0-1.11.2-0.8-1.11.1-1.1-0.6-0.60.6
Bone: final moment0.60.91.50.8-0.90.80.9-0.9-1.01.21.10.81.21.0-1.01.1-0.8-1.11.1-1.1-0.7-0.70.7
Food consumed during 24 hour testing period0.40.50.9-0.40.5-0.5-0.50.60.6-0.6-0.2-0.6-0.8-0.60.8-0.80.60.9-0.90.90.90.9-1.0
Glucose1.82.85.5-2.22.3-2.2-2.32.12.1-1.8-1.3-1.6-2.0-1.61.6-1.10.61.0-1.01.41.31.3-1.3
Heart weight0.30.51.7-1.31.1-1.1-1.10.90.7-0.5-1.0-0.5-0.1-0.5-0.00.40.6-0.50.5-0.3-0.0-0.00.0
Delay discount hyperbolic model param0.20.20.50.7-0.50.60.5-0.5-0.30.20.70.4-0.40.4-0.0-0.2-0.70.2-0.20.2-0.2-0.20.2
Intermittent access intake day 1-15 change1.02.03.4-1.21.4-1.3-1.41.41.5-1.2-0.8-1.2-1.8-1.21.5-1.31.11.4-1.41.61.71.7-1.7
Intermittent access intake escalation1.02.14.0-1.21.5-1.3-1.41.41.5-1.3-0.7-1.2-2.0-1.11.6-1.41.01.4-1.41.71.71.7-1.7
Intermittent access intake escalation 20.50.61.3-0.60.7-0.7-0.70.70.8-0.5-0.2-0.5-1.2-0.50.8-0.60.40.7-0.70.81.11.1-1.1
Intermitt. access day 1 inactive lever presses0.10.20.9-0.40.6-0.4-0.50.40.5-0.30.0-0.2-0.9-0.10.5-0.40.50.4-0.40.60.50.5-0.5
Intermitt. access day 15 inactive lever presses0.51.13.30.0-0.10.10.1-0.5-0.51.21.11.10.61.3-1.21.8-1.4-1.71.7-1.3-0.6-0.60.6
Intermitt. access escalation Index0.81.12.1-1.21.1-1.1-1.11.11.1-1.1-1.4-1.1-0.6-1.11.0-0.91.40.9-0.90.90.90.9-0.8
Intermittent access day 1 total infusions0.40.61.9-1.41.2-1.3-1.20.80.7-0.0-0.10.3-0.10.3-0.41.3-0.2-1.11.1-0.6-0.2-0.20.2
Intermittent access day 15 total infusions2.23.26.6-2.52.6-2.5-2.52.22.3-1.6-1.2-1.3-2.1-1.31.5-0.71.30.9-0.91.41.71.7-1.8
Intermittent access terminal intake (last 3 days)0.60.82.6-1.61.6-1.6-1.61.21.2-0.5-0.2-0.2-1.1-0.20.40.40.1-0.30.30.30.70.7-0.8
Intermittent access total infusions0.80.93.0-1.71.7-1.7-1.71.31.2-0.6-0.5-0.3-0.9-0.30.30.50.4-0.30.30.20.60.6-0.7
Intermittent access day 1 locomotion0.30.41.5-0.70.5-0.5-0.50.20.10.30.30.60.30.6-0.71.2-0.2-1.21.2-0.8-0.5-0.50.5
Intermittent access day 15 total locomotion0.30.51.8-0.60.6-0.6-0.60.20.20.50.70.7-0.20.7-0.71.3-0.7-1.21.2-0.7-0.2-0.20.2
Intermittent access total locomotion0.70.82.5-1.31.3-1.3-1.20.70.70.30.40.6-0.40.6-0.61.6-0.4-1.41.4-0.7-0.1-0.1-0.1
Intermittent access standard deviation0.10.20.7-0.30.4-0.3-0.40.40.5-0.40.1-0.2-0.8-0.20.5-0.50.00.5-0.50.70.50.5-0.6
Left kidney weight0.31.33.9-2.01.7-1.9-1.81.51.3-0.9-1.5-1.0-0.4-0.90.50.20.3-0.10.10.10.90.9-1.0
Right kidney weight0.10.51.7-1.31.2-1.3-1.21.00.9-0.6-0.8-0.6-0.2-0.60.30.10.2-0.10.10.10.40.4-0.5
Cocaine induced anxiety0.10.10.50.6-0.50.50.5-0.5-0.40.40.70.4-0.00.4-0.10.00.0-0.00.00.0-0.1-0.10.1
Post-drug Anxiety0.30.30.80.5-0.40.50.5-0.5-0.50.60.90.60.20.6-0.50.6-0.6-0.60.6-0.5-0.4-0.40.4
Baseline Anxiety0.10.20.40.0-0.10.10.1-0.2-0.30.30.00.20.70.2-0.50.5-0.5-0.60.6-0.6-0.4-0.40.5
Tail length0.20.71.81.1-1.31.21.2-1.0-1.10.60.30.11.30.2-0.60.2-1.1-0.30.3-0.7-0.6-0.60.6
Length with tail0.94.08.41.8-2.22.02.0-2.0-2.22.01.31.52.71.5-2.22.0-2.9-2.02.0-2.3-1.6-1.61.5
Length without tail2.47.613.42.5-2.72.52.6-2.7-2.82.82.52.63.42.5-2.82.7-3.7-2.82.8-2.9-2.6-2.62.5
Times rat made contact with spout0.30.30.90.9-0.90.90.9-0.8-0.70.60.60.40.50.4-0.40.0-0.6-0.10.1-0.2-0.5-0.50.4
Lifetime Intake0.40.51.9-1.41.3-1.3-1.31.00.9-0.4-0.4-0.1-0.6-0.10.10.50.2-0.40.4-0.00.20.2-0.3
Liver weight, left0.61.01.4-0.91.0-0.9-1.01.01.1-1.0-0.8-1.1-1.2-1.01.1-1.20.61.1-1.11.20.80.8-0.9
Liver weight, right1.32.23.4-1.61.8-1.7-1.81.71.8-1.6-1.0-1.5-1.4-1.51.7-1.40.51.4-1.41.61.21.2-1.3
Locomotor activity0.71.12.4-0.60.8-0.8-0.80.91.0-1.4-1.0-1.3-0.4-1.31.3-1.50.41.4-1.41.20.60.6-0.8
Locomotor testing distance0.50.91.9-0.60.9-0.8-0.90.91.0-1.2-0.5-1.1-0.5-1.01.3-1.40.71.2-1.21.20.50.5-0.6
Locomotor testing rearing0.40.91.9-0.50.8-0.7-0.80.81.0-1.2-0.2-0.8-0.9-0.81.3-1.40.51.3-1.31.40.60.6-0.8
Locomotion in novel chamber1.72.23.3-1.71.8-1.8-1.81.71.7-1.5-1.3-1.3-1.4-1.31.4-1.11.31.2-1.21.31.51.5-1.5
Locomotion in novel chamber post-restriction0.81.41.9-0.91.0-1.0-1.01.11.2-1.2-1.0-1.2-1.4-1.11.3-1.41.11.4-1.41.41.21.2-1.1
Fecal boli incidents, locomotor time 10.10.20.80.3-0.00.20.1-0.30.00.10.90.1-0.80.2-0.00.2-0.9-0.10.10.20.40.4-0.4
Change in fecal boli incidents, locomotor task2.22.23.4-1.81.7-1.8-1.81.81.6-1.5-1.9-1.6-0.7-1.71.4-1.21.61.2-1.21.11.11.1-1.1
Time >=10cm from walls, locomotor time 10.91.02.3-1.31.4-1.3-1.31.11.2-0.8-0.6-0.6-1.5-0.60.7-0.20.90.4-0.40.81.11.1-1.1
Bouts of movement, locomotor time 11.82.15.22.3-2.12.22.1-2.0-1.71.21.71.00.61.1-1.10.6-2.2-0.60.6-0.7-0.7-0.70.7
Total resting periods, locomotor time 11.21.33.61.9-1.71.71.7-1.6-1.40.91.50.80.50.8-0.90.5-1.9-0.50.5-0.6-0.4-0.40.4
Rest time, locomotor task time 10.81.01.8-0.80.9-0.9-0.90.81.0-1.3-0.8-1.2-1.3-1.10.9-0.80.30.9-0.91.01.11.1-1.1
Distance moved, locomotor task time 10.10.10.5-0.10.0-0.0-0.00.1-0.10.50.10.60.30.5-0.20.30.7-0.30.3-0.3-0.5-0.50.5
Vertical activity count, locomotor time 10.61.55.3-1.31.2-1.2-1.21.41.2-0.9-1.4-0.9-0.6-0.91.3-1.32.31.2-1.21.10.80.8-0.8
Time >=10cm from walls, locomotor time 20.20.30.9-0.20.3-0.3-0.30.30.4-0.1-0.1-0.2-0.9-0.20.5-0.40.80.5-0.50.60.80.8-0.8
Bouts of movement, locomotor time 23.55.79.22.6-2.42.62.5-2.7-2.42.13.02.61.32.6-2.32.1-2.7-2.12.1-1.9-2.3-2.32.3
Total resting periods, locomotor time 22.74.88.32.4-2.22.42.3-2.5-2.21.82.92.41.02.4-2.11.9-2.5-2.02.0-1.7-2.1-2.12.1
Rest time, locomotor task time 20.50.72.0-0.80.9-0.9-0.90.81.0-1.3-0.6-0.8-1.4-0.70.8-0.70.10.7-0.70.90.40.4-0.4
Distance moved, locomotor task time 20.10.11.10.3-0.30.20.3-0.1-0.20.2-0.20.10.4-0.00.2-0.41.10.4-0.40.10.30.3-0.3
Vertical activity count, locomotor time 20.71.03.6-0.50.4-0.5-0.40.80.6-0.7-1.3-0.80.1-0.91.1-1.51.91.4-1.41.00.70.7-0.7
Light reinforcement 10.10.30.8-0.10.4-0.3-0.40.30.5-0.20.2-0.5-0.7-0.40.7-0.60.30.6-0.60.80.90.9-0.9
Light reinforcement 20.71.12.5-1.31.3-1.3-1.31.11.1-0.5-0.8-1.0-1.0-1.00.6-0.10.70.3-0.30.51.61.6-1.5
Bone: marrow area1.43.17.6-2.72.5-2.6-2.52.32.1-1.6-2.0-1.7-1.8-1.61.1-0.31.30.5-0.50.81.61.6-1.6
Bone: maximum diameter0.10.20.4-0.60.4-0.5-0.50.30.20.1-0.4-0.10.1-0.1-0.20.5-0.0-0.40.4-0.40.60.6-0.6
Bone: maximum force1.01.73.80.7-0.90.80.9-1.1-1.21.71.11.01.61.3-1.62.0-1.0-1.91.9-1.8-0.9-0.90.9
Bone: maximum moment1.01.73.60.7-0.90.80.9-1.1-1.21.71.11.11.61.3-1.61.9-1.1-1.81.8-1.7-0.9-0.90.9
Mean time between licks in bursts0.41.12.61.0-1.01.11.0-1.0-1.00.91.01.10.91.1-0.90.60.1-0.80.8-0.8-1.6-1.61.5
Mean num. licks in bursts0.10.10.40.6-0.40.50.4-0.2-0.10.10.50.1-0.00.10.3-0.60.30.6-0.60.5-0.1-0.10.1
Cd content in liver0.91.01.4-0.91.0-1.0-1.01.01.1-0.9-0.6-0.9-1.0-0.91.1-1.01.21.0-1.01.11.01.0-1.0
Co content in liver0.70.81.8-0.40.4-0.4-0.50.70.7-1.0-1.0-1.0-0.8-1.01.1-1.41.21.3-1.31.10.70.7-0.7
Cu content in liver0.10.10.5-0.20.1-0.1-0.10.20.1-0.3-0.7-0.50.1-0.50.2-0.40.30.4-0.40.20.20.2-0.2
Fe content in liver0.00.00.0-0.10.1-0.1-0.10.10.0-0.0-0.1-0.0-0.0-0.0-0.10.1-0.1-0.10.1-0.1-0.1-0.10.1
K content in liver0.10.10.4-0.0-0.0-0.00.0-0.1-0.20.40.10.30.40.3-0.40.60.0-0.50.6-0.5-0.3-0.30.2
Mg content in liver0.00.00.1-0.30.4-0.3-0.30.20.3-0.00.1-0.10.1-0.10.10.1-0.2-0.10.10.0-0.1-0.10.1
Mn content in liver2.32.63.31.4-1.61.51.6-1.6-1.71.81.21.71.71.7-1.81.8-0.9-1.71.7-1.8-1.6-1.61.5
Na content in liver0.10.11.00.5-0.20.30.3-0.3-0.20.41.00.40.20.4-0.10.20.0-0.20.2-0.0-0.1-0.10.1
Rb content in liver2.22.53.0-1.51.7-1.6-1.61.71.7-1.7-1.4-1.6-1.7-1.61.7-1.71.51.6-1.61.71.41.4-1.4
Se content in liver0.20.20.70.1-0.30.20.3-0.4-0.40.40.10.50.20.5-0.70.8-0.2-0.70.7-0.7-0.4-0.40.4
Sr content in liver6.15.36.32.4-2.42.42.4-2.4-2.42.32.22.32.22.3-2.22.0-2.1-2.12.1-2.1-2.5-2.52.5
Zn content in liver2.62.94.01.7-1.71.71.7-1.8-1.81.81.71.72.01.7-1.61.5-1.2-1.51.5-1.7-1.9-1.91.9
Bone: minimum diameter0.91.73.9-2.01.9-1.9-1.91.61.5-1.0-1.2-1.2-1.2-1.10.7-0.11.10.2-0.20.51.31.3-1.3
Time in familiar zone, hab. session 10.00.00.30.1-0.00.10.0-0.1-0.10.30.40.1-0.00.2-0.10.2-0.5-0.20.2-0.10.10.1-0.1
Time in novel zone, hab. session 11.11.11.6-0.91.0-0.9-1.01.01.1-1.2-0.7-1.0-1.2-1.01.2-1.21.01.2-1.21.20.90.9-0.9
Total zone transitions, hab. session 10.30.40.70.8-0.80.80.8-0.7-0.70.60.60.70.80.5-0.40.2-0.4-0.30.3-0.4-0.7-0.70.6
Total locomotion distance, hab. session 10.10.20.50.1-0.00.10.1-0.2-0.20.40.50.7-0.00.5-0.50.6-0.4-0.60.6-0.5-0.6-0.60.6
Locomotion velocity, hab. session 10.60.81.40.7-0.70.70.7-0.8-0.80.90.91.20.61.0-0.90.9-0.8-1.01.0-0.9-1.1-1.11.1
Time in familiar zone, hab. session 20.91.01.5-0.50.7-0.6-0.70.80.9-0.9-0.6-1.1-1.0-1.01.2-1.20.91.2-1.21.21.21.2-1.2
Time in novel zone, hab. session 20.80.81.20.6-0.60.60.6-0.7-0.80.90.91.01.00.9-0.91.0-0.7-1.01.0-1.0-1.1-1.11.1
Total zone transitions, hab. session 20.70.91.91.1-0.91.01.0-1.0-0.91.11.41.01.10.9-0.70.7-0.7-0.70.7-0.7-0.9-0.90.9
Total locomotion distance, hab. session 20.30.41.10.6-0.40.50.5-0.6-0.50.71.00.90.30.7-0.50.6-0.7-0.70.7-0.5-0.8-0.80.7
Locomotion velocity, hab. session 20.20.20.60.3-0.10.20.2-0.3-0.30.50.80.70.10.5-0.40.6-0.5-0.60.6-0.4-0.6-0.60.5
Novel to familiar place preference ratio1.31.43.20.8-1.11.01.0-1.0-1.21.10.40.91.81.0-1.41.3-1.0-1.31.4-1.6-1.2-1.21.2
Novelty place preference0.80.92.00.5-0.80.70.7-0.8-1.00.80.20.71.40.7-1.21.1-0.8-1.11.1-1.3-1.0-1.01.0
Time in novel zone, NPP test1.31.42.30.7-1.00.91.0-1.0-1.21.00.51.01.51.0-1.41.3-1.2-1.41.4-1.5-1.3-1.31.3
Total zone transitions, NPP test1.11.62.51.6-1.41.51.5-1.4-1.31.41.51.41.31.3-0.90.7-0.9-0.80.8-0.9-1.4-1.41.3
Total locomotion distance, NPP test0.10.20.30.5-0.40.40.4-0.4-0.40.40.50.50.50.3-0.20.2-0.2-0.20.2-0.3-0.6-0.60.5
Locomotion velocity, NPP test0.00.00.20.2-0.20.20.2-0.1-0.10.10.10.10.4-0.10.1-0.20.40.1-0.10.0-0.1-0.10.1
Intraocular pressure0.00.00.20.4-0.30.40.3-0.3-0.2-0.00.20.1-0.40.1-0.0-0.1-0.10.1-0.10.1-0.1-0.10.1
Delta distance traveled before/after self-admin0.20.20.6-0.10.1-0.0-0.00.20.2-0.6-0.5-0.4-0.4-0.40.4-0.70.80.6-0.60.5-0.2-0.20.1
Delta ambulatory time before/after self-admin0.30.41.0-0.10.2-0.1-0.20.30.4-0.8-0.5-0.6-0.6-0.60.7-1.01.00.9-0.90.80.20.2-0.2
Parametrial fat weight2.66.213.5-3.73.2-3.5-3.33.12.7-2.3-3.4-2.5-1.7-2.41.6-0.61.90.9-0.91.12.52.5-2.5
Pavlov. Cond. lever latency0.20.20.6-0.40.3-0.3-0.30.40.4-0.7-0.7-0.7-0.8-0.40.4-0.60.20.5-0.50.50.20.2-0.2
Pavlov. Cond. magazine entry latency0.60.71.50.6-0.60.60.6-0.8-0.71.21.21.00.51.0-0.91.2-0.9-1.11.1-0.9-0.4-0.40.4
Pavlov. Cond. change in total contacts0.20.20.70.4-0.30.30.3-0.4-0.30.70.80.70.20.6-0.40.5-0.2-0.40.4-0.3-0.0-0.00.0
Pavlov. Cond. index score0.20.30.70.6-0.50.50.5-0.6-0.50.80.80.70.50.6-0.50.6-0.6-0.50.5-0.5-0.1-0.10.1
Pavlov. Cond. latency score0.10.10.40.3-0.20.20.2-0.3-0.30.60.60.50.40.3-0.30.4-0.4-0.40.4-0.30.10.1-0.1
Pavlov. Cond. lever contacts0.00.00.20.00.0-0.1-0.0-0.0-0.00.30.30.20.40.1-0.10.30.1-0.20.2-0.10.20.2-0.2
Pavlov. Cond. magazine entry number0.50.61.3-0.90.8-0.8-0.90.90.8-1.2-1.0-0.9-0.5-0.90.8-0.80.70.7-0.70.70.30.3-0.3
Pavlov. Cond. intertrial magazine entries0.10.10.30.5-0.30.30.3-0.2-0.10.00.40.10.20.00.4-0.5-0.10.5-0.50.40.00.0-0.1
Pavlov. Cond. lever-magazine prob. diff.0.30.40.80.7-0.60.60.6-0.7-0.60.90.90.80.50.7-0.60.7-0.5-0.60.6-0.5-0.2-0.20.2
Pavlov. Cond. response bias0.50.61.20.8-0.70.70.7-0.8-0.81.11.11.00.60.9-0.80.9-0.5-0.80.8-0.7-0.3-0.30.3
Pavlov. Cond. lever latency1.11.52.8-0.90.9-0.9-0.91.11.0-1.3-1.7-1.6-0.4-1.51.3-1.61.61.5-1.51.20.90.9-0.9
Pavlov. Cond. magazine entry latency6.88.211.12.8-2.82.82.8-3.0-2.93.23.33.32.03.3-3.03.0-3.0-2.92.9-2.7-2.5-2.52.5
Pavlov. Cond. change in total contacts1.62.55.51.5-1.31.41.4-1.6-1.41.92.32.20.52.0-1.61.8-2.1-1.71.7-1.3-1.0-1.00.9
Pavlov. Cond. index score4.05.48.42.0-2.02.12.0-2.3-2.22.62.82.81.22.7-2.52.7-2.9-2.62.6-2.3-1.8-1.81.8
Pavlov. Cond. latency score3.85.08.21.9-1.91.91.9-2.2-2.12.52.72.71.22.6-2.42.7-2.9-2.62.6-2.2-1.7-1.71.7
Pavlov. Cond. lever contacts1.31.73.61.1-1.01.11.1-1.3-1.11.41.91.80.21.6-1.41.5-1.9-1.51.5-1.1-1.0-1.00.9
Pavlov. Cond. magazine entry number10.212.716.1-3.43.5-3.5-3.53.73.6-3.9-3.9-4.0-2.6-3.93.8-3.73.83.7-3.63.53.13.1-3.1
Pavlov. Cond. intertrial magazine entries1.72.63.5-1.31.5-1.5-1.51.61.7-1.7-1.5-1.7-1.4-1.71.9-1.91.31.8-1.81.81.51.5-1.6
Pavlov. Cond. lever-magazine prob. diff.4.56.09.22.2-2.12.22.2-2.5-2.32.73.03.01.32.8-2.62.8-3.0-2.72.7-2.3-1.9-1.91.9
Pavlov. Cond. response bias3.14.16.51.8-1.71.81.8-2.0-1.92.32.52.51.12.4-2.22.3-2.2-2.32.3-1.9-1.7-1.71.6
Time in closed arm before self-admin0.30.41.1-0.70.7-0.8-0.70.60.7-0.3-0.2-0.5-0.7-0.50.4-0.10.30.2-0.20.41.01.0-1.0
Time in closed arm after self-admin0.50.60.9-0.70.8-0.8-0.80.80.8-1.0-0.7-1.0-0.6-0.90.8-0.70.00.7-0.70.70.80.8-0.8
Time in open arm before self-admin1.11.22.5-0.90.8-0.8-0.91.11.0-1.4-1.6-1.3-0.2-1.31.2-1.61.21.4-1.41.10.30.3-0.3
Time in open arm after self-admin0.40.40.80.8-0.90.80.8-0.7-0.70.50.20.60.80.5-0.40.10.3-0.20.2-0.5-0.9-0.90.9
Bone: periosteal estimation0.30.72.0-1.41.2-1.3-1.21.00.9-0.4-0.9-0.8-0.5-0.60.20.30.6-0.20.20.01.01.0-1.0
Bone: periosteal perimeter0.20.30.8-0.80.9-0.9-0.80.70.7-0.2-0.3-0.4-0.4-0.40.30.10.1-0.10.10.20.80.8-0.8
Bone: post-yield work0.81.13.3-1.81.6-1.7-1.61.31.1-0.5-1.1-0.8-0.7-0.80.20.60.3-0.40.4-0.11.21.2-1.2
Progressive ratio test 1 active lever presses0.10.10.3-0.60.5-0.5-0.50.40.4-0.2-0.2-0.1-0.3-0.10.10.20.2-0.10.10.00.10.1-0.1
Progressive ratio test 1 breakpoint0.10.10.3-0.50.5-0.5-0.50.40.4-0.2-0.1-0.1-0.3-0.10.00.20.1-0.20.2-0.00.10.1-0.1
Progressive ratio test 1 inactive lever presses1.62.43.90.9-1.01.01.0-1.3-1.31.61.51.71.31.8-1.82.0-1.5-2.02.0-1.8-1.5-1.51.5
Progressive ratio test 2 active lever presses0.50.61.6-1.21.3-1.2-1.21.01.0-0.5-0.3-0.4-1.0-0.50.40.10.40.0-0.00.40.70.7-0.7
Progressive ratio test 2 breakpoint0.50.61.6-1.21.3-1.2-1.21.01.0-0.5-0.3-0.3-0.9-0.40.40.20.3-0.10.10.30.70.7-0.7
Progressive ratio test 2 inactive lever presses0.20.31.1-1.01.0-1.0-1.00.70.7-0.10.1-0.1-0.70.00.10.5-0.0-0.40.40.10.50.5-0.5
Incentive Sensitization - Responses0.40.61.90.1-0.20.20.2-0.4-0.50.90.91.00.30.9-1.01.4-0.7-1.31.3-1.0-0.6-0.60.6
Incentive Sensitization - Breakpoint0.40.51.8-0.10.0-0.0-0.0-0.3-0.30.80.80.80.20.8-0.91.3-0.6-1.21.2-0.9-0.5-0.50.5
Sum of active levers in priming session hrs 5-60.60.51.21.1-1.01.01.0-1.0-0.90.90.80.90.41.0-0.60.4-0.4-0.30.3-0.4-0.4-0.40.4
Progressive ratio0.10.10.5-0.50.4-0.5-0.40.20.20.1-0.00.1-0.10.1-0.30.7-0.0-0.60.6-0.40.20.2-0.1
Food seeking constrained by brief footshock0.00.00.2-0.10.2-0.1-0.20.10.2-0.20.1-0.2-0.3-0.20.2-0.20.50.1-0.10.30.10.1-0.1
Seeking ratio, punishment vs. effort0.10.10.30.3-0.30.30.3-0.2-0.2-0.10.1-0.00.2-0.00.1-0.30.00.2-0.20.1-0.6-0.60.4
Retroperitoneal fat weight3.013.022.8-4.84.6-4.7-4.64.44.2-3.8-4.2-3.7-3.3-3.63.1-2.12.22.3-2.32.63.23.2-3.2
Reaction time number correct0.20.32.30.8-0.70.70.6-0.6-0.50.50.80.00.70.2-0.20.0-1.5-0.10.1-0.1-0.2-0.20.0
Reaction time mean minus median0.30.81.51.2-1.11.21.2-1.1-1.01.01.21.10.61.0-0.70.5-0.7-0.50.5-0.6-0.6-0.60.8
Reaction time mean minus median AUC0.20.61.71.3-1.11.21.1-1.0-0.80.71.10.80.20.7-0.3-0.1-0.70.0-0.0-0.1-0.4-0.40.5
Reaction time num false alarms0.20.30.9-0.30.2-0.3-0.30.40.4-0.7-0.8-0.9-0.1-0.70.7-0.90.60.8-0.80.60.20.2-0.1
Reaction time num false alarms AUC0.10.20.60.2-0.30.20.20.0-0.1-0.4-0.6-0.60.6-0.40.3-0.80.50.6-0.60.2-0.2-0.20.2
Reaction time trials correct on left0.20.32.30.8-0.70.70.6-0.6-0.50.50.80.00.70.2-0.20.0-1.5-0.10.1-0.1-0.2-0.20.0
Reaction time trials on left0.20.42.40.9-0.70.70.7-0.6-0.60.50.80.10.70.2-0.20.0-1.6-0.10.1-0.1-0.2-0.20.0
Reaction time mean0.10.21.10.7-0.40.60.5-0.5-0.40.61.00.9-0.30.7-0.10.10.2-0.10.00.1-0.2-0.20.4
Reaction time mean AUC0.10.10.70.4-0.10.30.2-0.2-0.10.30.90.6-0.60.40.1-0.10.40.1-0.20.40.10.10.1
Median of all reaction times0.10.20.80.5-0.30.40.4-0.4-0.30.50.90.8-0.30.6-0.20.20.3-0.20.2-0.0-0.2-0.20.4
Reaction time omissions0.30.40.91.0-0.90.90.9-0.8-0.80.60.60.70.50.6-0.40.2-0.7-0.20.2-0.3-0.4-0.40.5
Reaction time false alarm rate0.20.31.5-0.50.3-0.4-0.30.50.4-0.7-1.0-0.60.0-0.60.5-0.71.20.6-0.60.30.10.10.0
Reaction time premature initiation rate2.23.05.80.9-1.41.11.2-1.4-1.71.70.91.72.41.6-2.12.3-1.2-2.22.2-2.4-1.7-1.71.7
Reaction time premature initiations2.13.87.51.6-1.91.71.8-1.9-2.12.01.41.72.71.7-2.22.1-2.1-2.12.1-2.3-1.8-1.81.7
Std. dev. reaction times0.10.20.60.8-0.60.70.6-0.5-0.30.30.60.5-0.20.30.1-0.40.20.4-0.40.3-0.0-0.00.2
Reaction time trials completed0.20.42.40.9-0.70.70.7-0.6-0.60.50.80.10.70.2-0.20.0-1.6-0.10.1-0.1-0.2-0.20.0
Reaction time trials AUC0.20.32.40.8-0.60.60.6-0.5-0.50.40.80.00.60.2-0.2-0.0-1.6-0.10.1-0.1-0.2-0.20.0
Run reversals in cocaine runway, females0.20.20.9-0.40.2-0.3-0.20.1-0.10.1-0.30.20.90.3-0.50.7-0.2-0.70.7-0.7-0.6-0.60.5
Run reversals in cocaine runway, males1.71.73.9-1.11.1-1.2-1.11.31.2-1.4-1.6-1.4-0.5-1.41.4-1.52.01.5-1.51.21.11.1-1.3
Latency to leave start box in cocaine runway1.11.22.8-1.71.5-1.6-1.51.41.2-0.8-1.3-1.1-0.5-1.10.7-0.20.80.3-0.30.41.21.2-1.1
Latency to leave start box in cocaine runway, F0.10.10.2-0.50.3-0.4-0.40.20.20.0-0.3-0.20.3-0.1-0.20.4-0.1-0.40.4-0.30.20.2-0.1
Latency to leave start box in cocaine runway, M3.12.94.0-2.01.9-2.0-1.91.91.8-1.6-1.9-1.8-1.5-1.81.5-1.21.61.3-1.31.41.81.8-1.7
Std. dev. time between licks in bursts0.20.31.0-0.50.5-0.5-0.50.50.5-0.6-0.5-0.5-0.2-0.50.5-0.51.00.5-0.50.50.20.2-0.3
Total sessions with >9 infusions0.10.10.2-0.50.5-0.4-0.40.30.3-0.3-0.00.0-0.40.10.00.10.4-0.10.10.1-0.1-0.10.1
Short access day 1 total inactive lever presses0.00.00.2-0.40.3-0.4-0.30.20.2-0.0-0.2-0.10.2-0.1-0.10.30.2-0.30.3-0.2-0.1-0.10.1
Short access day 10 total inactive lever presses0.00.10.40.10.10.0-0.00.10.2-0.30.1-0.1-0.60.00.4-0.60.60.5-0.50.60.10.1-0.1
Short access day 1 total infusions0.50.61.2-1.11.1-1.1-1.11.01.0-0.9-0.8-0.7-0.7-0.70.7-0.50.70.5-0.50.70.60.6-0.6
Short access day 10 total infusions0.30.31.0-1.00.9-0.9-0.90.60.50.00.00.3-0.20.3-0.30.90.1-0.90.9-0.4-0.2-0.20.2
Short access total infusions0.20.31.0-1.00.9-0.9-0.90.70.6-0.3-0.3-0.1-0.2-0.0-0.00.40.2-0.40.4-0.1-0.1-0.10.1
Short access day 1 locomotion0.10.10.2-0.40.3-0.4-0.40.30.3-0.2-0.3-0.2-0.1-0.20.10.00.30.0-0.00.10.20.2-0.2
Short access day 10 total locomotion0.40.82.4-0.20.1-0.0-0.1-0.3-0.30.71.01.10.01.1-1.01.5-0.6-1.51.5-1.0-0.9-0.90.8
Short access total locomotion0.30.31.1-0.40.3-0.3-0.30.0-0.00.40.50.6-0.00.7-0.61.1-0.3-1.01.0-0.6-0.5-0.50.4
One hour access (0.3 mA shock)0.70.92.3-1.51.5-1.5-1.51.21.2-0.7-0.7-0.6-1.1-0.70.50.10.50.0-0.00.40.80.8-0.8
Compulsive drug intake1.01.22.41.5-1.51.61.5-1.3-1.30.70.90.90.90.8-0.80.3-1.1-0.40.4-0.7-1.3-1.31.3
One hour access (shock baseline)2.64.07.1-2.62.6-2.7-2.62.42.4-1.7-1.7-1.7-2.0-1.81.7-0.91.71.1-1.11.52.12.1-2.1
Social response proportion0.50.61.2-0.70.6-0.7-0.70.70.6-0.7-0.9-1.0-0.1-0.90.7-0.70.80.7-0.70.61.11.1-1.1
Social responses0.30.41.0-0.10.0-0.1-0.10.30.3-0.7-0.7-0.80.0-0.70.7-1.00.61.0-1.00.70.90.9-0.9
Social time0.10.20.70.7-0.60.60.5-0.3-0.2-0.30.2-0.10.0-0.20.4-0.80.20.7-0.70.50.10.1-0.1
Soleus weight2.77.99.9-2.52.8-2.7-2.82.83.0-3.0-2.2-2.5-3.1-2.63.1-2.92.62.9-2.93.12.72.7-2.8
Bone: stiffness0.10.10.5-0.0-0.10.00.1-0.2-0.30.50.10.10.40.3-0.50.7-0.2-0.60.6-0.60.20.2-0.2
Tibialis anterior weight8.629.135.75.5-5.75.65.6-5.7-5.85.55.05.46.05.5-5.34.7-4.9-4.94.9-5.3-5.5-5.55.5
Time to tail flick, vehicle, before self-admin0.20.20.7-0.20.1-0.1-0.1-0.1-0.10.30.10.30.40.4-0.50.8-0.1-0.80.8-0.6-0.2-0.20.2
Time to tail flick, vehicle, after self-admin0.71.01.80.5-0.60.60.6-0.8-0.80.90.80.90.90.9-1.11.3-1.3-1.31.3-1.2-1.0-1.00.9
Time to tail flick, test, before self-admin0.20.20.5-0.50.3-0.4-0.30.20.1-0.1-0.4-0.10.70.0-0.40.6-0.5-0.60.6-0.6-0.3-0.30.4
Time to tail flick, test, after self-admin0.00.00.10.10.00.00.00.00.1-0.10.1-0.1-0.40.10.2-0.20.20.3-0.30.30.30.3-0.3
Delta time to tail flick, vehicle, before/after SA0.70.71.80.9-0.90.90.9-0.9-0.90.80.90.70.70.6-0.80.6-1.3-0.70.7-0.7-0.8-0.80.8
Delta time to tail flick, test, before/after SA0.30.31.01.0-0.80.90.8-0.7-0.50.40.70.5-0.50.40.1-0.40.30.4-0.40.40.10.1-0.1
Tibia length0.71.83.01.1-1.31.21.2-1.3-1.41.61.11.31.71.4-1.51.7-1.5-1.61.6-1.6-0.9-0.90.7
Ambulatory time before self-admin0.71.01.60.9-0.90.80.9-1.0-1.01.31.31.20.71.2-1.11.3-1.2-1.21.2-1.0-0.5-0.50.5
Ambulatory time after self-admin0.10.10.30.2-0.20.20.2-0.3-0.20.30.50.4-0.10.4-0.30.5-0.4-0.40.4-0.3-0.0-0.0-0.0
Bone: tissue strength0.80.91.2-0.80.9-0.8-0.90.90.9-0.9-0.7-1.1-0.9-0.91.0-1.01.01.0-1.01.00.90.9-0.9
Total heroin consumption5.26.19.73.0-3.13.03.1-2.9-2.92.52.12.42.62.4-2.31.6-1.8-1.71.7-2.2-2.3-2.32.4
Bone: trabecular number0.60.91.90.4-0.60.50.6-0.7-0.80.90.61.01.21.0-1.21.4-0.8-1.31.3-1.3-0.9-0.90.9
Bone: trabecular spacing0.30.41.40.30.10.10.00.10.3-0.40.4-0.4-0.8-0.40.9-1.20.41.1-1.11.10.40.4-0.4
Bone: trabecular thickness0.40.50.8-0.90.8-0.9-0.80.80.7-0.7-0.8-0.8-0.6-0.60.5-0.3-0.10.4-0.40.40.80.8-0.8
Bone: trabecular tissue density3.85.66.8-2.02.1-2.1-2.12.32.4-2.5-2.2-2.5-2.6-2.42.5-2.52.22.6-2.62.62.32.3-2.3
Water consumed over 24 hours0.20.30.60.5-0.80.60.7-0.6-0.70.50.10.30.70.3-0.60.4-0.7-0.40.4-0.6-0.3-0.30.2
Number of responses in last shaping day0.70.71.21.0-1.11.01.0-0.9-1.00.70.50.71.10.7-0.80.5-0.4-0.60.6-0.8-1.0-1.01.0