Hub : Genes

Mmd2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Mmd2 0.16 0.06 0.0e+00 0.21 0.19 0.2 0.21 4.4e-23 2.2e-20 4.0e-22 1.9e-22
2 Adipose isoform ratio XM_063271264.1 0.11 0.04 1.9e-14 0.13 0.11 0.1 0.11 2.5e-14 2.1e-12 6.0e-11 5.6e-12
3 Adipose alternative polyA XM_063271263.1 0.12 0.05 0.0e+00 0.17 0.15 0.14 0.15 4.1e-18 5.6e-16 7.0e-15 3.8e-16
4 Adipose alternative polyA XM_063271264.1 0.12 0.05 0.0e+00 0.17 0.15 0.14 0.15 3.2e-18 4.8e-16 5.2e-15 2.9e-16
5 Adipose isoform ratio NM_001037217.1 0.11 0.04 3.6e-14 0.13 0.11 0.1 0.1 7.0e-14 2.3e-12 1.5e-11 2.6e-11
6 BLA gene expression Mmd2 0.07 0.05 2.1e-03 0.03 0.03 0.01 0.04 9.2e-03 6.9e-03 9.6e-02 2.6e-03
7 pVTA gene expression Mmd2 0.14 0.05 1.1e-13 0.12 0.17 0.16 0.16 4.0e-10 2.2e-13 7.5e-13 3.0e-13
8 NAcc gene expression Mmd2 0.18 0.06 0.0e+00 0.2 0.2 0.19 0.2 1.5e-29 1.5e-29 2.8e-28 1.3e-29
9 PL gene expression Mmd2 0.12 0.05 1.6e-14 0.13 0.14 0.14 0.14 1.0e-13 1.4e-15 2.1e-15 1.9e-15
10 Brain gene expression Mmd2 0.36 0.09 0.0e+00 0.32 0.38 0.39 0.38 1.6e-30 6.5e-38 1.9e-38 8.1e-37
11 NAcc mRNA stability Mmd2 0.16 0.06 5.6e-17 0.13 0.12 0.12 0.13 3.5e-19 1.0e-17 2.0e-17 2.8e-19
12 Liver mRNA stability Mmd2 0.07 0.04 1.1e-05 0.03 0.04 0.04 0.04 6.5e-04 1.5e-05 3.9e-05 5.5e-05
13 PL mRNA stability Mmd2 0.14 0.05 1.3e-14 0.13 0.14 0.14 0.14 2.5e-14 1.2e-14 3.1e-15 7.9e-15
14 RMTg gene expression Mmd2 0.15 0.09 7.6e-03 0.13 0.06 0.06 0.09 2.7e-04 9.0e-03 1.0e-02 2.7e-03
15 LHb gene expression Mmd2 0.23 0.11 1.5e-03 0.11 0.08 0.1 0.1 1.2e-03 4.9e-03 2.5e-03 2.3e-03
16 OFC gene expression Mmd2 0.48 0.15 1.5e-04 0.06 0.14 0.11 0.14 1.3e-02 4.2e-04 1.3e-03 4.2e-04
17 Liver alternative polyA XM_063271263.1 0.09 0.05 1.3e-06 0.06 0.06 0.06 0.06 2.7e-07 9.7e-07 9.5e-07 3.8e-07
18 Liver gene expression Mmd2 0.34 0.12 1.1e-11 0.12 0.09 0.1 0.11 1.1e-12 3.8e-10 2.3e-11 6.9e-12
19 pVTA mRNA stability Mmd2 0.08 0.04 4.8e-05 0.07 0.05 0.06 0.05 1.9e-06 4.6e-05 1.7e-05 3.6e-05
20 Liver alternative polyA XM_063271264.1 0.1 0.05 2.4e-08 0.08 0.07 0.08 0.08 1.2e-09 9.5e-09 5.2e-09 2.2e-09
21 BLA mRNA stability Mmd2 0.14 0.07 2.9e-04 0.03 0.03 0.04 0.02 9.8e-03 6.5e-03 5.8e-03 3.9e-02
22 Eye gene expression Mmd2 0.37 0.21 9.1e-03 0.08 0.07 0.06 0.12 2.1e-02 2.8e-02 4.7e-02 6.8e-03
23 Brain mRNA stability Mmd2 0.41 0.09 0.0e+00 0.38 0.43 0.41 0.42 1.2e-36 1.5e-43 4.8e-41 1.1e-42
24 Liver intron excision ratio chr12_17076470_17077124 0.08 0.03 1.1e-07 0.01 0.06 0.06 0.05 1.3e-02 1.6e-07 1.9e-07 1.7e-06
25 Liver intron excision ratio chr12_17076470_17106372 0.05 0.03 1.2e-04 0.02 0.03 0.03 0.05 8.8e-04 6.2e-04 3.2e-04 5.2e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25
Bone: apparent density1.12.13.4-1.71.7-1.71.7-1.8-1.5-1.6-1.6-1.61.5-1.4-1.11.71.61.5-0.51.61.61.6-1.60.9-0.2-1.3-1.30.3
Area under the delay curve1.52.35.01.7-1.51.5-1.51.41.31.81.21.3-1.61.92.2-1.8-1.4-1.51.7-1.6-1.6-1.61.6-1.4-0.61.60.9-0.5
BMI with tail0.31.02.9-1.51.5-1.51.5-1.4-1.7-1.0-1.1-1.10.9-0.4-0.40.40.70.9-0.20.40.40.4-0.40.0-1.70.30.9-1.2
BMI without tail0.63.28.8-2.52.8-2.82.8-2.8-2.9-1.7-1.8-1.61.4-0.2-1.10.11.01.0-0.80.10.10.1-0.10.2-3.00.62.2-2.4
Body weight1.35.512.7-3.43.2-3.23.2-3.0-3.6-2.7-3.1-2.92.30.0-1.90.92.62.6-2.01.61.61.6-1.61.5-2.6-0.71.1-1.3
Weight adjusted by age1.13.311.0-1.81.6-1.61.6-1.5-1.5-1.9-1.3-1.81.4-1.7-2.12.12.31.9-2.71.61.61.6-1.63.30.2-1.7-1.01.6
Bone surface1.83.66.1-2.22.3-2.32.3-2.4-1.6-2.1-1.6-1.71.6-1.9-1.82.51.71.6-1.62.02.02.0-2.02.00.5-2.0-1.70.9
Bone volume2.34.67.0-2.52.6-2.62.6-2.6-2.0-2.4-2.1-2.22.1-2.2-2.02.62.02.0-1.62.22.22.2-2.21.9-0.0-2.1-1.70.7
Breakpoint value in progressive ratio session0.91.73.40.6-0.40.4-0.40.50.81.41.21.2-1.61.81.3-1.7-0.9-1.21.3-1.9-1.9-1.91.9-0.5-0.51.91.4-1.0
Number of licking bursts0.41.23.7-1.91.8-1.81.8-1.8-0.9-1.0-0.2-0.30.5-0.9-1.21.0-0.4-0.4-0.30.90.90.9-0.9-0.61.0-0.70.3-1.6
Context. condit. distance diff. score0.91.02.3-1.21.3-1.31.3-1.4-1.4-1.3-1.5-1.41.4-0.9-1.10.71.21.3-0.30.40.40.4-0.40.6-0.6-0.8-0.40.0
Locomotion velocity, session 10.91.03.91.3-1.21.2-1.21.52.01.01.10.9-0.70.40.7-0.2-0.5-0.50.3-0.4-0.4-0.40.4-0.31.7-0.5-1.21.6
Locomotion distance, session 10.50.62.41.0-0.90.9-0.91.01.60.81.10.9-0.7-0.60.50.3-0.5-0.50.0-0.1-0.1-0.10.1-0.21.3-0.3-1.11.2
Locomotion velocity, session 20.20.21.10.5-0.40.4-0.40.51.00.40.60.3-0.4-0.20.50.3-0.3-0.10.00.10.10.1-0.1-0.10.5-0.1-0.91.1
Locomotion distance, session 20.71.02.50.7-0.60.6-0.60.81.31.21.41.4-1.20.01.2-0.4-1.4-1.51.1-0.8-0.8-0.80.8-1.60.51.00.3-0.6
Locomotion velocity, session 30.81.01.91.2-1.21.2-1.21.40.91.00.40.4-0.81.21.2-1.2-0.3-0.30.9-1.2-1.2-1.21.2-0.9-0.81.00.4-0.1
Locomotion distance, session 30.20.21.30.3-0.40.4-0.40.4-0.00.1-0.4-0.40.2-0.00.20.00.80.80.4-0.0-0.0-0.00.0-0.0-1.10.1-0.40.6
Stereotopy head waving bouts, day 30.50.62.4-0.20.1-0.10.10.0-0.4-0.9-0.9-0.80.8-1.3-0.31.10.70.7-1.60.70.70.7-0.71.0-0.4-0.7-0.60.6
Stereotopy head waving duration, day 30.10.10.40.4-0.50.5-0.50.50.40.10.20.2-0.4-0.10.3-0.2-0.3-0.3-0.6-0.5-0.5-0.50.50.30.20.20.20.0
Locomotion velocity, session 70.80.91.60.4-0.40.4-0.40.61.01.21.11.1-1.31.00.9-1.0-0.9-1.01.3-1.3-1.3-1.31.3-1.00.41.10.5-0.4
Locomotion distance, session 71.11.53.30.3-0.20.2-0.20.30.71.41.31.3-1.51.41.2-1.3-1.1-1.11.7-1.5-1.5-1.51.5-1.4-0.11.81.3-1.1
Stereotopy head waving bouts, day 70.81.02.8-0.90.9-0.90.9-0.9-1.4-1.3-1.7-1.31.5-1.1-1.00.91.21.1-0.90.40.40.4-0.40.8-1.3-0.5-0.1-0.1
Stereotopy head waving duration, day 70.20.21.3-0.20.0-0.00.0-0.1-0.6-0.4-0.8-0.50.8-0.4-0.40.10.40.30.1-0.3-0.3-0.30.3-0.2-1.10.10.3-0.4
Locomotion velocity, session 80.30.42.7-0.30.2-0.20.2-0.3-0.2-0.6-0.5-0.60.8-1.7-0.41.20.50.6-0.00.60.60.6-0.60.10.0-0.6-1.00.8
Locomotion distance, session 80.10.20.8-0.50.5-0.50.5-0.5-0.5-0.5-0.7-0.60.6-0.9-0.00.70.50.60.00.00.00.0-0.0-0.5-0.60.0-0.3-0.2
Degree of sensitization distance0.40.51.8-0.20.3-0.30.3-0.20.60.61.21.1-1.00.50.2-0.3-1.2-1.20.2-0.4-0.4-0.40.4-0.41.30.50.6-0.6
Degree of sensitization stereotypy1.31.43.6-1.21.1-1.11.1-1.2-1.7-1.5-1.9-1.61.8-1.3-1.41.11.51.4-0.60.60.60.6-0.60.9-1.4-0.6-0.2-0.1
Conditioned locomotion0.60.71.4-1.01.1-1.11.1-1.2-0.9-1.0-0.8-0.71.0-1.0-0.91.00.40.4-0.70.90.90.9-0.90.60.2-0.8-0.4-0.2
Cocaine response after cond. corrected0.40.61.71.2-1.21.2-1.21.31.30.70.80.7-0.5-0.20.60.0-0.2-0.30.3-0.2-0.2-0.20.2-0.60.90.0-1.00.8
Cocaine response after cond. not corrected0.20.30.90.9-0.90.9-0.90.90.90.50.60.6-0.3-0.40.6-0.0-0.4-0.50.20.00.00.0-0.0-0.70.50.1-0.60.3
Cocaine response before conditioning0.30.41.6-0.70.8-0.80.8-0.8-0.9-0.4-0.4-0.20.3-0.1-0.2-0.1-0.3-0.30.20.30.30.3-0.3-0.5-1.10.51.1-1.3
Saline control response2.43.47.5-2.72.7-2.72.7-2.7-2.5-2.0-1.7-1.51.8-1.3-2.51.51.01.1-1.51.51.51.5-1.51.2-0.9-0.90.9-1.1
Bone: connectivity density0.71.12.6-1.41.3-1.31.3-1.6-0.7-1.0-0.6-0.60.8-1.1-1.01.60.70.6-0.31.11.11.1-1.10.50.9-1.0-1.10.1
Bone: cortical apparent density1.42.14.8-1.21.3-1.31.3-1.3-2.1-1.8-2.2-1.91.8-0.9-1.01.21.91.9-1.31.21.21.2-1.22.0-1.4-1.0-0.40.5
Bone: cortical area0.81.24.3-2.12.0-2.02.0-2.0-1.4-1.0-0.7-0.50.4-0.3-0.90.60.20.2-0.80.70.70.7-0.70.8-0.1-0.20.8-1.2
Bone: cortical porosity0.20.20.9-0.20.2-0.20.2-0.3-0.4-0.0-0.3-0.30.1-0.20.3-0.40.10.10.9-0.6-0.6-0.60.6-0.8-0.80.80.4-0.7
Bone: cortical porosity0.20.20.6-0.60.7-0.70.7-0.8-0.6-0.5-0.5-0.60.5-0.7-0.30.30.60.60.30.00.00.0-0.0-0.0-0.70.1-0.1-0.3
Bone: cortical thickness0.50.82.3-1.41.3-1.31.3-1.3-1.5-0.8-0.9-0.70.40.0-0.30.10.60.6-0.60.20.20.2-0.20.6-1.20.41.2-1.1
Bone: cortical thickness0.40.51.8-1.11.3-1.31.3-1.1-0.9-0.5-0.4-0.30.2-0.1-0.50.00.30.3-0.70.20.20.2-0.20.6-0.3-0.10.7-0.5
Bone: cortical tissue density1.42.35.1-1.21.3-1.31.3-1.3-2.2-1.9-2.3-2.01.9-0.9-1.11.32.02.0-1.31.21.21.2-1.22.0-1.5-1.0-0.50.5
Condit. Reinf. active minus inactive responses0.10.10.50.3-0.20.2-0.20.20.60.60.70.5-0.7-0.20.70.0-0.3-0.30.4-0.2-0.2-0.20.2-0.10.10.3-0.40.2
Condit. Reinf. active-inactive response ratio0.50.61.70.8-0.60.6-0.60.51.11.01.21.0-1.30.41.0-0.4-0.6-0.70.4-0.7-0.7-0.70.7-0.00.80.5-0.20.3
Condit. Reinf. active responses0.20.30.6-0.70.7-0.70.7-0.8-0.00.20.60.4-0.6-0.20.30.2-0.7-0.70.6-0.2-0.2-0.20.2-0.4-0.40.60.5-0.7
Condit. Reinf. inactive responses0.50.62.0-1.41.3-1.31.3-1.3-0.9-0.4-0.1-0.20.2-0.3-0.40.2-0.5-0.40.50.00.00.0-0.0-0.5-1.00.61.1-1.4
Incentive salience index mean0.20.31.10.2-0.10.1-0.10.10.60.70.90.6-1.00.31.0-0.4-0.5-0.50.6-0.5-0.5-0.50.5-0.7-0.30.70.1-0.3
Condit. Reinf. lever presses0.10.20.8-0.70.7-0.70.7-0.6-0.3-0.00.0-0.1-0.40.10.40.1-0.1-0.10.3-0.1-0.1-0.10.1-0.7-0.90.60.2-0.8
Condit. Reinf. active minus inactive responses0.60.92.3-1.31.2-1.21.2-1.2-1.3-1.2-1.1-1.01.1-1.5-0.60.80.70.6-0.30.50.50.5-0.5-0.1-1.10.00.4-0.8
Condit. Reinf. active-inactive response ratio0.30.61.2-1.11.0-1.01.0-1.1-0.9-0.9-0.9-0.81.0-1.1-0.90.60.70.7-0.10.50.50.5-0.50.2-0.3-0.4-0.0-0.2
Condit. Reinf. active responses1.01.43.5-1.41.5-1.51.5-1.5-1.7-1.5-1.5-1.41.5-1.9-0.91.31.00.9-0.40.80.80.8-0.80.2-1.3-0.30.1-0.7
Condit. Reinf. inactive responses0.30.51.2-0.30.4-0.40.4-0.3-1.0-0.9-1.1-1.01.0-1.0-0.31.00.90.9-0.60.50.50.5-0.50.4-1.1-0.2-0.3-0.0
Condit. Reinf. lever presses1.31.94.3-1.61.7-1.71.7-1.7-2.1-1.8-1.7-1.51.6-2.1-1.41.61.31.3-0.71.01.01.0-1.00.4-1.3-0.40.1-0.7
Condit. Reinf. lever reinforcers received1.01.43.5-1.41.4-1.41.4-1.4-1.8-1.5-1.5-1.31.6-1.9-1.01.20.90.9-0.30.80.80.8-0.80.1-1.4-0.20.3-0.9
Conditioned reinforcement - actives0.20.63.4-1.31.3-1.31.3-1.1-1.0-0.3-0.5-0.10.10.5-0.3-0.3-0.2-0.20.60.00.00.0-0.0-0.9-0.10.41.3-1.9
Conditioned reinforcement - inactives0.10.21.00.10.3-0.30.3-0.2-0.4-0.3-0.7-0.60.4-0.10.40.20.10.20.30.20.20.2-0.2-1.0-1.00.1-0.1-0.6
Conditioned locomotion0.60.94.2-1.51.5-1.51.5-1.3-1.1-0.2-0.3-0.0-0.00.7-0.3-0.5-0.2-0.10.5-0.4-0.4-0.40.4-0.5-0.70.81.8-2.1
Patch foraging indifference point 0 sec0.10.20.90.00.0-0.00.0-0.10.2-0.00.60.4-0.4-0.5-0.20.4-0.8-0.9-0.60.50.50.5-0.50.30.9-0.30.2-0.3
Patch foraging indifference point AUC1.53.65.9-2.42.3-2.32.3-2.3-2.3-2.4-1.9-1.92.1-1.7-2.41.81.21.3-2.21.91.91.9-1.91.8-0.7-1.60.3-0.5
Delay disc. indifference point, 0s delay0.20.20.70.7-0.80.8-0.80.80.40.10.0-0.1-0.1-0.30.20.20.20.1-0.20.30.30.3-0.30.20.1-0.4-0.70.8
Delay disc. indifference point, 16s delay2.83.96.22.2-1.91.9-1.91.81.82.41.72.1-1.92.32.5-2.3-2.3-2.12.2-2.1-2.1-2.12.1-2.1-0.02.01.4-0.9
Delay disc. indifference point, 2s delay0.10.10.40.3-0.20.2-0.20.10.30.10.20.0-0.3-0.30.20.00.1-0.2-0.5-0.0-0.0-0.00.00.60.1-0.2-0.20.5
Delay disc. indifference point, 24s delay0.40.61.70.8-0.90.9-0.90.71.21.01.01.0-0.80.20.9-0.3-1.3-1.30.7-0.3-0.3-0.30.3-0.41.30.1-0.20.3
Delay disc. indifference point, 4s delay2.02.14.01.9-1.71.7-1.71.61.31.71.31.1-1.52.01.9-1.7-0.8-1.01.1-1.6-1.6-1.61.6-0.9-0.81.40.60.1
Delay disc. indifference point, 8s delay1.52.56.11.6-1.51.5-1.51.51.21.81.01.1-1.52.12.5-2.0-1.0-1.22.0-1.9-1.9-1.91.9-1.5-1.31.80.8-0.5
Indifference point function ln k1.23.66.92.4-2.32.3-2.32.32.32.31.91.9-2.01.62.5-1.7-1.4-1.52.6-1.7-1.7-1.71.7-1.60.81.5-0.40.3
Indifference point function log k1.23.66.92.4-2.32.3-2.32.32.32.31.91.9-2.01.62.5-1.7-1.4-1.52.6-1.7-1.7-1.71.7-1.60.81.5-0.40.3
Patch foraging total patch changes 0 sec0.10.31.70.5-0.40.4-0.40.30.70.30.90.8-0.7-0.20.10.1-1.0-1.2-0.30.30.30.3-0.30.21.3-0.20.1-0.2
Patch foraging total patch changes 12 sec1.72.36.4-1.71.5-1.51.5-1.5-1.3-1.8-0.9-1.01.3-1.5-2.21.70.50.6-2.51.91.91.9-1.91.50.8-1.8-0.1-0.1
Patch foraging total patch changes 18 sec0.51.22.8-1.41.5-1.51.5-1.3-1.1-1.2-0.8-0.80.9-1.1-1.70.90.50.4-1.51.11.11.1-1.11.10.3-1.10.4-0.4
Patch foraging total patch changes 24 sec0.62.15.2-1.61.5-1.51.5-1.4-1.9-1.9-1.5-1.61.4-1.3-1.91.51.21.0-2.31.41.41.4-1.41.7-0.8-1.20.3-0.5
Patch foraging total patch changes 6 sec0.50.82.1-1.21.0-1.01.0-1.0-1.1-1.0-0.3-0.20.5-0.8-1.40.8-0.4-0.4-1.40.80.80.8-0.80.30.4-0.51.1-1.4
Patch foraging time to switch 0 sec0.31.12.30.6-0.90.9-0.91.01.31.21.31.4-1.30.90.4-1.0-0.9-0.90.9-1.4-1.4-1.41.4-1.50.90.80.1-0.1
Patch foraging water rate 0 sec0.10.51.3-0.40.8-0.80.8-0.8-0.8-0.7-0.7-0.80.6-0.7-0.20.70.50.5-0.51.11.11.1-1.10.9-0.4-0.5-0.20.1
Patch foraging water rate 12 sec0.41.64.2-0.41.0-1.01.0-0.8-0.6-1.1-1.2-1.40.9-1.7-0.51.71.71.6-0.81.31.31.3-1.31.70.0-1.2-2.11.7
Patch foraging water rate 18 sec0.00.00.40.10.2-0.20.2-0.2-0.00.20.10.0-0.3-0.00.50.00.00.10.6-0.0-0.0-0.00.00.0-0.00.3-0.40.1
Patch foraging water rate 24 sec0.91.32.7-0.90.8-0.80.8-0.8-0.6-1.0-0.8-1.00.9-1.4-0.91.50.70.7-0.51.71.71.7-1.71.20.9-1.4-1.40.9
Patch foraging water rate 6 sec0.20.31.20.20.2-0.20.2-0.00.10.50.30.1-0.51.01.1-0.7-0.1-0.20.4-0.4-0.4-0.40.40.1-1.00.80.7-0.1
Seeking ratio, delayed vs. immediate footshock0.20.21.0-0.60.9-0.90.9-1.0-0.3-0.2-0.00.2-0.10.0-0.4-0.0-0.3-0.3-0.40.00.00.0-0.0-0.20.10.20.8-1.0
Distance traveled before self-admin0.10.21.20.5-0.70.7-0.70.70.40.2-0.1-0.0-0.20.20.50.10.20.3-0.30.00.00.0-0.00.3-0.2-0.2-0.61.1
Distance traveled after self-admin0.10.20.60.1-0.30.3-0.30.3-0.00.30.30.3-0.50.70.3-0.30.20.1-0.2-0.8-0.8-0.80.80.5-0.40.70.50.1
Extensor digitorum longus weight1.76.913.4-3.73.6-3.63.6-3.6-3.0-3.0-2.7-2.82.7-2.1-3.02.52.52.4-1.92.42.42.4-2.41.9-0.4-2.1-1.0-0.1
Bone: elastic displacement2.32.96.4-0.50.4-0.40.4-0.6-1.4-1.8-2.3-2.11.9-2.5-1.02.02.52.5-1.91.81.81.8-1.82.0-0.8-1.4-1.81.5
Bone: elastic work2.93.86.1-1.91.8-1.81.8-2.0-2.2-2.3-2.3-2.21.8-2.1-1.41.82.12.0-2.52.22.22.2-2.22.4-1.1-1.4-0.50.3
Bone: endosteal estimation0.10.20.9-0.70.9-0.90.9-0.9-0.0-0.20.10.1-0.20.0-0.40.4-0.4-0.4-0.30.30.30.3-0.3-0.10.9-0.4-0.1-0.4
Bone: endosteal perimeter0.30.93.9-1.01.1-1.11.1-1.20.0-0.50.20.10.2-0.8-1.11.1-0.2-0.3-0.51.21.21.2-1.20.22.0-1.2-0.7-0.3
Epididymis fat weight0.41.96.02.4-2.32.3-2.32.41.91.10.90.7-1.10.91.2-0.60.30.3-0.00.40.40.4-0.40.01.2-0.4-2.02.1
Delta time in closed arm before/after self-admin0.90.94.3-2.11.0-1.01.0-0.9-1.7-1.0-1.2-0.71.0-0.3-0.70.60.40.40.10.40.40.4-0.40.2-0.80.11.3-1.4
Delta time in open arm before/after self-admin2.73.27.32.4-1.01.0-1.00.82.52.42.72.4-2.41.91.5-2.1-2.2-2.11.3-1.8-1.8-1.81.8-0.91.41.30.6-0.0
Diff in mean of infusions in LGA sessions1.01.83.30.4-0.80.8-0.80.50.91.61.61.6-1.51.70.7-1.7-1.6-1.71.5-1.6-1.6-1.61.6-0.80.21.41.8-1.2
Delay discount exponential model param2.02.85.9-1.81.6-1.61.6-1.5-1.4-1.9-1.3-1.51.7-2.1-2.42.01.51.7-1.81.81.81.8-1.81.60.7-1.7-1.10.7
Extinction: sum of active levers before priming0.20.41.6-1.21.2-1.21.2-1.3-0.4-0.3-0.2-0.20.10.3-0.30.10.30.1-0.4-0.0-0.0-0.00.00.6-0.1-0.10.5-0.2
Active lever presses in extinction session 60.60.61.8-0.60.4-0.40.4-0.40.3-0.50.0-0.20.1-0.9-0.71.00.50.3-1.30.80.80.8-0.81.31.1-1.1-1.21.3
Bone: final force1.21.95.7-2.32.3-2.32.3-2.4-1.9-1.1-1.1-0.90.30.6-0.6-0.20.1-0.0-0.80.20.20.2-0.20.1-1.70.52.1-2.3
Bone: final moment1.32.16.0-2.32.3-2.32.3-2.4-2.1-1.2-1.3-1.00.50.6-0.5-0.20.30.1-0.70.10.10.1-0.1-0.0-2.00.62.2-2.4
Food consumed during 24 hour testing period0.10.20.60.2-0.10.1-0.10.00.40.30.70.7-0.40.30.00.1-0.8-0.8-0.00.00.00.0-0.0-0.50.70.20.3-0.5
Glucose1.82.86.22.3-2.52.5-2.52.12.22.12.01.9-2.01.81.7-1.7-1.1-1.10.7-1.1-1.1-1.11.1-0.51.60.90.10.6
Heart weight0.30.41.10.8-1.01.0-1.01.10.70.70.50.4-0.70.60.9-0.60.10.00.1-0.5-0.5-0.50.50.1-0.30.3-0.30.8
Delay discount hyperbolic model param1.41.84.1-1.61.3-1.31.3-1.2-1.1-1.6-1.0-1.11.4-1.7-2.01.61.21.4-1.41.51.51.5-1.51.30.7-1.4-0.90.5
Intermittent access intake day 1-15 change0.10.42.4-0.20.4-0.40.4-0.2-0.50.2-0.4-0.3-0.21.10.6-0.80.50.60.3-0.8-0.8-0.80.8-0.5-1.50.90.8-0.6
Intermittent access intake escalation0.10.41.1-0.40.6-0.60.6-0.5-0.40.2-0.2-0.1-0.31.00.4-0.70.30.40.4-0.7-0.7-0.70.7-0.5-1.10.80.7-0.7
Intermittent access intake escalation 20.10.20.8-0.30.4-0.40.4-0.2-0.40.0-0.3-0.1-0.00.90.1-0.60.50.50.3-0.6-0.6-0.60.6-0.3-0.90.50.5-0.3
Intermitt. access day 1 inactive lever presses0.00.10.30.10.0-0.00.00.1-0.4-0.1-0.2-0.00.40.3-0.1-0.1-0.0-0.00.30.10.10.1-0.1-0.1-0.50.20.4-0.5
Intermitt. access day 15 inactive lever presses0.10.30.8-0.70.8-0.80.8-0.6-0.7-0.4-0.5-0.70.6-0.0-0.30.10.60.7-0.10.10.10.1-0.1-0.3-0.9-0.00.2-0.6
Intermitt. access escalation Index0.20.74.10.3-0.40.4-0.40.30.3-0.3-0.2-0.20.5-1.1-0.50.90.60.5-0.50.90.90.9-0.91.00.8-1.1-1.62.0
Intermittent access day 1 total infusions0.10.40.90.2-0.20.2-0.20.10.60.80.90.8-0.91.00.2-0.8-0.7-0.60.6-0.6-0.6-0.60.6-0.60.90.50.4-0.4
Intermittent access day 15 total infusions0.10.41.50.00.2-0.20.2-0.10.40.70.70.6-0.81.20.2-0.9-0.2-0.00.7-0.8-0.8-0.80.8-0.70.30.60.3-0.1
Intermittent access terminal intake (last 3 days)0.10.20.70.3-0.10.1-0.10.10.60.60.70.5-0.60.80.0-0.6-0.00.10.4-0.4-0.4-0.40.4-0.40.70.1-0.30.5
Intermittent access total infusions0.60.71.60.8-0.60.6-0.60.51.01.11.21.0-1.11.30.6-1.1-0.6-0.50.9-0.9-0.9-0.90.9-0.90.80.60.10.2
Intermittent access day 1 locomotion0.20.41.1-0.10.1-0.10.1-0.10.30.70.90.8-0.71.0-0.1-0.9-0.6-0.70.8-0.6-0.6-0.60.6-0.50.70.60.7-0.7
Intermittent access day 15 total locomotion0.10.41.1-0.91.0-1.01.0-1.0-0.60.00.10.1-0.20.8-0.6-0.60.30.20.1-0.5-0.5-0.50.5-0.2-0.10.41.0-1.0
Intermittent access total locomotion0.30.31.20.00.1-0.10.1-0.10.30.60.80.8-0.71.1-0.1-0.9-0.4-0.50.3-0.7-0.7-0.70.7-0.20.60.50.9-0.5
Intermittent access standard deviation0.21.23.41.2-1.21.2-1.21.20.71.10.50.4-0.81.81.3-1.6-0.2-0.01.1-1.3-1.3-1.31.3-1.2-1.11.20.50.0
Left kidney weight0.10.92.6-1.41.6-1.61.6-1.6-1.2-0.8-1.0-0.90.60.6-0.6-0.00.80.7-0.40.90.90.9-0.90.90.0-0.60.2-0.3
Right kidney weight0.21.33.0-1.31.3-1.31.3-1.2-0.7-0.8-0.5-0.70.4-0.1-0.90.70.60.6-1.01.71.71.7-1.71.61.0-1.3-0.60.6
Cocaine induced anxiety0.10.20.40.40.0-0.00.0-0.10.30.50.40.6-0.60.40.6-0.6-0.5-0.50.4-0.5-0.5-0.50.50.20.10.60.6-0.1
Post-drug Anxiety0.30.31.4-0.10.6-0.60.6-0.6-0.10.30.10.3-0.50.60.4-0.7-0.4-0.40.2-0.8-0.8-0.80.80.3-0.70.91.2-0.6
Baseline Anxiety0.10.10.7-0.30.2-0.20.2-0.1-0.2-0.1-0.1-0.1-0.10.30.1-0.2-0.1-0.2-0.0-0.4-0.4-0.40.4-0.3-0.80.50.7-0.8
Tail length1.26.313.4-3.43.3-3.33.3-3.3-3.7-3.1-3.3-2.92.6-0.6-2.41.32.62.5-2.91.71.71.7-1.72.2-2.1-1.40.9-0.9
Length with tail0.94.18.9-2.92.5-2.52.5-2.4-3.0-2.3-3.0-2.62.00.5-1.60.62.42.4-1.91.41.41.4-1.41.6-1.9-0.90.7-0.8
Length without tail0.20.81.7-1.20.7-0.70.7-0.5-0.9-0.9-1.2-1.20.80.7-0.80.31.31.3-1.11.11.11.1-1.11.0-0.1-0.9-0.20.3
Times rat made contact with spout0.00.00.20.1-0.00.0-0.0-0.0-0.3-0.0-0.3-0.10.20.50.4-0.10.10.10.40.00.00.0-0.0-0.3-0.20.10.2-0.2
Lifetime Intake0.60.71.70.5-0.20.2-0.20.10.91.11.21.0-1.21.30.6-1.1-0.8-0.61.1-1.0-1.0-1.01.0-1.10.80.80.3-0.2
Liver weight, left0.20.30.9-0.80.8-0.80.8-0.8-0.6-0.4-0.5-0.60.10.7-0.3-0.30.90.9-0.2-0.4-0.4-0.40.40.2-0.70.00.0-0.2
Liver weight, right0.20.41.6-0.91.0-1.01.0-1.1-0.8-0.4-0.3-0.20.30.3-0.5-0.1-0.00.0-0.1-0.1-0.1-0.10.1-0.2-0.20.31.2-1.3
Locomotor activity0.61.02.8-1.21.2-1.21.2-0.9-1.7-1.3-1.5-1.31.3-0.4-0.90.41.11.1-0.50.80.80.8-0.80.0-1.1-0.30.6-0.7
Locomotor testing distance0.30.71.6-1.01.3-1.31.3-1.1-1.3-0.9-1.2-0.90.9-0.1-0.60.10.90.8-0.10.30.30.3-0.3-0.3-1.0-0.00.5-0.8
Locomotor testing rearing0.72.57.6-2.72.6-2.62.6-2.4-2.1-1.8-1.5-1.51.5-0.7-2.10.90.90.9-0.70.80.80.8-0.80.2-0.9-0.60.9-1.4
Locomotion in novel chamber0.10.10.9-0.4-0.20.2-0.20.2-0.3-0.0-0.00.30.10.3-0.3-0.2-0.5-0.40.20.00.00.0-0.0-0.30.4-0.10.6-0.9
Locomotion in novel chamber post-restriction0.20.73.1-0.0-0.40.4-0.40.4-0.1-0.5-0.5-0.60.8-1.2-0.71.01.11.0-0.30.90.90.9-0.90.70.7-1.0-1.81.3
Fecal boli incidents, locomotor time 10.20.61.3-1.10.7-0.70.7-0.5-1.1-0.9-1.1-1.01.1-0.6-1.10.70.80.8-0.30.70.70.7-0.70.4-0.7-0.60.2-0.4
Change in fecal boli incidents, locomotor task0.10.10.20.1-0.30.3-0.30.30.00.10.20.1-0.20.30.1-0.30.00.1-0.3-0.4-0.4-0.40.4-0.3-0.40.40.4-0.1
Time >=10cm from walls, locomotor time 10.91.12.7-0.2-0.50.5-0.50.5-0.6-1.1-1.1-1.11.1-1.6-0.81.41.21.3-1.51.21.21.2-1.20.8-0.3-1.2-1.21.0
Bouts of movement, locomotor time 10.70.92.8-0.40.8-0.80.8-0.50.20.80.70.8-1.11.10.8-1.1-1.1-1.11.4-1.0-1.0-1.01.0-1.00.11.11.3-1.7
Total resting periods, locomotor time 10.70.83.0-0.60.8-0.80.8-0.5-0.00.70.60.7-0.90.90.6-1.0-1.0-1.01.3-0.9-0.9-0.90.9-0.80.21.01.4-1.7
Rest time, locomotor task time 10.30.61.7-1.31.2-1.21.2-0.8-0.30.10.40.5-0.40.6-0.7-0.6-0.6-0.70.6-0.4-0.4-0.40.4-0.20.70.21.3-1.2
Distance moved, locomotor task time 10.30.93.82.0-1.51.5-1.51.50.60.1-0.2-0.30.2-0.31.00.30.70.7-0.90.20.20.2-0.20.4-0.8-0.2-1.41.5
Vertical activity count, locomotor time 10.10.43.90.4-0.30.3-0.30.1-0.7-0.4-0.9-0.70.9-0.20.50.10.50.50.20.10.10.1-0.1-0.8-2.00.4-0.0-0.5
Time >=10cm from walls, locomotor time 20.41.25.30.8-0.90.9-0.91.00.3-0.4-0.3-0.80.1-1.1-0.10.91.71.6-1.80.70.70.7-0.71.6-0.1-1.1-1.82.3
Bouts of movement, locomotor time 20.00.10.30.2-0.40.4-0.40.6-0.2-0.1-0.3-0.3-0.10.00.4-0.10.50.5-0.10.10.10.1-0.10.5-0.3-0.2-0.50.2
Total resting periods, locomotor time 20.00.10.3-0.1-0.20.2-0.20.4-0.30.1-0.2-0.1-0.30.20.5-0.30.10.10.2-0.2-0.2-0.20.20.0-0.30.20.1-0.5
Rest time, locomotor task time 21.01.77.7-1.10.7-0.70.7-0.4-0.30.60.71.1-0.91.2-0.1-1.4-1.6-1.61.3-1.3-1.3-1.31.3-1.40.01.42.8-2.7
Distance moved, locomotor task time 20.91.25.42.1-1.31.3-1.31.30.9-0.0-0.2-0.70.3-0.21.00.51.11.0-1.50.60.60.6-0.60.8-0.3-0.9-2.12.3
Vertical activity count, locomotor time 20.82.04.6-0.20.4-0.40.4-0.4-1.3-1.6-1.9-2.11.9-1.2-0.71.42.12.0-1.41.51.51.5-1.50.9-1.7-1.3-1.51.2
Light reinforcement 10.83.77.2-2.32.3-2.32.3-2.0-2.2-2.3-2.0-1.91.8-2.2-2.12.01.51.5-2.71.81.81.8-1.81.9-0.5-1.60.1-0.2
Light reinforcement 20.51.02.2-0.10.3-0.30.3-0.3-0.7-1.0-1.1-1.21.1-1.5-0.41.21.11.2-1.01.31.31.3-1.31.3-0.4-1.1-1.31.1
Bone: marrow area0.10.20.9-0.70.9-0.90.9-0.90.0-0.30.10.1-0.10.0-0.40.4-0.4-0.3-0.30.30.30.3-0.3-0.11.0-0.5-0.1-0.3
Bone: maximum diameter0.30.71.5-1.11.2-1.21.2-1.2-0.2-0.6-0.1-0.10.2-0.7-0.71.00.00.1-0.80.90.90.9-0.90.91.2-0.9-0.6-0.0
Bone: maximum force0.91.85.7-2.42.4-2.42.4-2.4-1.7-1.2-0.9-0.90.5-0.1-1.00.30.20.0-1.20.50.50.5-0.50.2-0.8-0.11.5-1.9
Bone: maximum moment0.91.85.3-2.32.3-2.32.3-2.3-1.9-1.2-1.1-1.00.50.0-0.80.20.40.2-1.00.50.50.5-0.50.0-1.20.11.5-2.0
Mean time between licks in bursts0.00.31.2-0.40.3-0.30.3-0.3-0.8-0.6-0.6-0.50.5-0.10.10.00.10.2-0.90.50.50.5-0.50.4-1.1-0.00.6-0.7
Mean num. licks in bursts0.41.13.31.8-1.71.7-1.71.60.61.00.00.4-0.41.31.4-1.20.30.30.8-0.9-0.9-0.90.9-0.1-1.11.00.11.0
Cd content in liver1.51.64.60.8-0.80.8-0.80.80.91.31.41.5-1.41.41.2-1.1-1.5-1.61.8-1.3-1.3-1.31.3-2.20.11.61.0-1.2
Co content in liver0.60.73.9-0.00.1-0.10.1-0.1-0.60.1-0.30.0-0.20.70.6-0.3-0.2-0.20.8-1.0-1.0-1.01.0-1.7-2.01.51.0-1.7
Cu content in liver0.20.21.60.7-0.60.6-0.60.80.40.50.20.1-0.1-0.00.4-0.20.10.11.3-0.1-0.1-0.10.1-0.1-0.30.2-0.60.4
Fe content in liver1.51.93.8-1.00.9-0.90.9-0.7-0.5-1.2-0.9-1.21.1-1.7-1.51.61.41.4-1.31.61.61.6-1.61.91.1-1.9-2.01.6
K content in liver0.40.42.70.7-0.60.6-0.60.60.60.70.50.5-0.21.00.4-0.8-0.7-0.71.6-0.4-0.4-0.40.4-0.9-0.20.2-0.30.1
Mg content in liver1.01.15.31.2-1.11.1-1.11.20.91.30.80.8-0.71.30.9-1.3-0.7-0.72.3-0.9-0.9-0.90.9-1.3-0.40.8-0.1-0.0
Mn content in liver1.21.35.2-1.21.3-1.31.3-1.4-0.90.20.00.3-0.40.90.3-1.0-1.1-1.11.1-1.0-1.0-1.01.0-0.4-1.31.42.3-2.1
Na content in liver1.01.15.40.9-0.80.8-0.81.10.6-0.3-0.3-0.70.2-0.4-0.30.81.41.4-1.00.70.70.7-0.71.50.0-1.3-2.32.3
Rb content in liver0.70.92.00.9-0.80.8-0.80.90.40.90.20.3-0.61.11.1-1.30.10.10.9-1.4-1.4-1.41.4-1.0-0.81.20.5-0.4
Se content in liver2.83.45.4-1.41.4-1.41.4-1.3-1.3-2.0-1.6-1.91.9-2.2-2.02.21.71.7-1.72.32.32.3-2.32.30.1-2.2-1.81.4
Sr content in liver0.20.20.5-0.70.6-0.60.6-0.6-0.6-0.6-0.3-0.30.1-0.3-0.60.50.1-0.0-0.60.30.30.3-0.30.6-0.3-0.20.1-0.3
Zn content in liver0.30.33.40.5-0.60.6-0.60.60.30.50.10.2-0.10.40.7-0.3-0.1-0.11.8-0.5-0.5-0.50.5-0.3-0.60.4-0.70.4
Bone: minimum diameter0.40.82.4-1.51.6-1.61.6-1.5-0.4-0.30.40.5-0.3-0.3-0.90.4-1.0-1.0-0.30.30.30.3-0.30.01.0-0.11.1-1.3
Time in familiar zone, hab. session 10.20.20.7-0.60.6-0.60.6-0.7-0.6-0.2-0.4-0.00.30.3-0.5-0.10.00.00.6-0.1-0.1-0.10.1-0.3-0.10.30.6-0.8
Time in novel zone, hab. session 10.20.20.60.5-0.60.6-0.60.80.70.50.40.3-0.5-0.00.4-0.3-0.4-0.40.2-0.5-0.5-0.50.5-0.20.20.1-0.10.4
Total zone transitions, hab. session 10.10.20.6-0.60.6-0.60.6-0.6-0.5-0.3-0.5-0.50.1-0.30.1-0.10.60.5-0.4-0.2-0.2-0.20.20.4-0.70.10.1-0.2
Total locomotion distance, hab. session 11.01.44.1-1.41.5-1.51.5-1.4-1.2-1.4-0.9-1.20.9-1.0-0.90.91.10.9-2.00.90.90.9-0.92.0-0.1-1.1-0.20.1
Locomotion velocity, hab. session 10.50.72.5-1.21.3-1.31.3-1.2-0.8-0.9-0.3-0.70.3-0.6-0.50.50.50.3-1.60.60.60.6-0.61.50.2-0.70.2-0.3
Time in familiar zone, hab. session 20.70.85.2-0.40.4-0.40.4-0.6-0.50.20.10.6-0.20.90.1-0.9-1.3-1.20.4-0.6-0.6-0.60.6-1.2-0.41.12.3-1.9
Time in novel zone, hab. session 20.30.32.50.3-0.30.3-0.30.60.50.10.0-0.30.1-0.30.20.30.70.70.40.10.10.1-0.10.40.3-0.6-1.61.3
Total zone transitions, hab. session 20.30.41.80.5-0.40.4-0.40.50.20.50.10.1-0.3-0.51.4-0.40.10.11.0-0.8-0.8-0.80.8-0.9-1.10.8-0.2-0.2
Total locomotion distance, hab. session 20.91.14.8-0.90.9-0.90.9-0.8-1.1-1.4-0.9-1.21.1-2.2-0.71.51.00.9-1.40.90.90.9-0.91.0-0.3-1.1-0.90.3
Locomotion velocity, hab. session 20.40.63.3-0.50.5-0.50.5-0.4-0.5-0.9-0.4-0.70.5-1.8-0.21.10.60.5-1.20.70.70.7-0.70.90.0-0.9-0.90.4
Novel to familiar place preference ratio0.10.10.60.1-0.10.1-0.10.10.40.00.2-0.00.0-0.4-0.00.3-0.1-0.20.10.60.60.6-0.60.20.3-0.5-0.80.6
Novelty place preference0.10.10.50.2-0.20.2-0.20.30.60.20.30.1-0.1-0.00.20.1-0.3-0.30.30.40.40.4-0.40.00.3-0.4-0.70.6
Time in novel zone, NPP test0.10.10.30.2-0.20.2-0.20.20.60.30.30.1-0.20.00.3-0.1-0.3-0.30.40.20.20.2-0.2-0.10.2-0.2-0.60.5
Total zone transitions, NPP test0.10.10.60.2-0.20.2-0.20.30.30.00.0-0.20.0-0.70.10.00.40.30.2-0.1-0.1-0.10.1-0.40.1-0.2-0.70.3
Total locomotion distance, NPP test0.30.41.6-0.40.3-0.30.3-0.2-0.2-0.6-0.2-0.50.4-1.2-0.60.80.60.5-1.10.50.50.5-0.50.80.3-0.9-0.70.5
Locomotion velocity, NPP test0.20.21.2-0.30.3-0.30.3-0.1-0.2-0.5-0.1-0.30.3-1.1-0.50.70.40.3-0.90.40.40.4-0.40.60.3-0.7-0.50.2
Intraocular pressure0.50.85.2-0.70.7-0.70.7-0.6-1.6-1.0-1.4-1.10.80.0-0.20.20.90.9-0.3-0.1-0.1-0.10.1-0.2-2.30.60.8-1.3
Delta distance traveled before/after self-admin0.20.21.2-0.30.4-0.40.4-0.40.10.30.80.7-0.60.2-0.6-0.2-0.3-0.4-0.2-0.5-0.5-0.50.50.31.10.30.7-0.4
Delta ambulatory time before/after self-admin0.10.21.1-0.40.3-0.30.3-0.30.10.20.70.6-0.5-0.1-0.4-0.0-0.4-0.4-0.4-0.3-0.3-0.30.30.41.10.20.6-0.4
Parametrial fat weight1.33.28.81.2-1.01.0-1.01.21.11.81.61.8-1.83.01.8-2.3-2.1-2.01.2-1.9-1.9-1.91.9-2.2-0.32.02.4-1.9
Pavlov. Cond. lever latency0.30.31.01.0-0.90.9-0.90.90.90.60.60.6-0.50.50.3-0.5-0.5-0.40.0-0.2-0.2-0.20.20.30.8-0.0-0.10.6
Pavlov. Cond. magazine entry latency0.20.20.80.6-0.70.7-0.70.70.50.20.10.0-0.2-0.50.60.10.50.60.3-0.3-0.3-0.30.3-0.50.10.1-0.90.6
Pavlov. Cond. change in total contacts0.10.10.3-0.1-0.10.1-0.1-0.0-0.2-0.0-0.1-0.2-0.0-0.40.5-0.10.40.40.4-0.4-0.4-0.40.4-0.5-0.60.4-0.2-0.2
Pavlov. Cond. index score0.10.20.8-0.30.1-0.10.1-0.2-0.5-0.4-0.5-0.60.4-0.60.00.40.80.90.0-0.2-0.2-0.20.2-0.3-0.80.0-0.4-0.0
Pavlov. Cond. latency score0.10.21.0-0.30.2-0.20.2-0.2-0.6-0.4-0.5-0.60.3-0.40.20.20.70.80.0-0.3-0.3-0.30.3-0.4-1.00.2-0.1-0.2
Pavlov. Cond. lever contacts0.20.20.9-0.70.5-0.50.5-0.5-0.8-0.5-0.5-0.50.4-0.4-0.10.30.50.50.1-0.1-0.1-0.10.1-0.5-0.90.20.1-0.6
Pavlov. Cond. magazine entry number0.20.30.6-0.40.5-0.50.5-0.6-0.3-0.3-0.00.00.30.1-0.80.2-0.6-0.7-0.20.80.80.8-0.80.60.6-0.50.5-0.2
Pavlov. Cond. intertrial magazine entries0.10.10.7-0.30.5-0.50.5-0.8-0.4-0.1-0.0-0.20.00.3-0.20.00.10.10.20.00.00.0-0.00.6-0.80.10.10.0
Pavlov. Cond. lever-magazine prob. diff.0.20.20.9-0.40.3-0.30.3-0.3-0.6-0.6-0.6-0.70.6-0.7-0.20.50.90.9-0.1-0.0-0.0-0.00.0-0.3-0.7-0.1-0.5-0.0
Pavlov. Cond. response bias0.10.10.8-0.30.2-0.20.2-0.1-0.1-0.3-0.2-0.30.1-0.80.10.50.60.7-0.00.00.00.0-0.0-0.1-0.2-0.2-0.90.4
Pavlov. Cond. lever latency3.14.37.32.1-2.12.1-2.12.12.72.62.62.6-2.52.42.0-2.4-2.5-2.41.8-1.8-1.8-1.81.8-1.51.81.20.6-0.1
Pavlov. Cond. magazine entry latency0.10.20.7-0.50.4-0.40.4-0.4-0.4-0.10.20.3-0.1-0.9-0.10.3-0.7-0.70.5-0.1-0.1-0.10.10.0-0.00.40.6-0.8
Pavlov. Cond. change in total contacts1.02.43.7-1.61.6-1.61.6-1.5-1.8-1.9-1.8-1.91.8-1.8-1.61.71.91.9-1.11.41.41.4-1.41.4-0.9-1.0-0.70.4
Pavlov. Cond. index score0.81.22.6-1.41.4-1.41.4-1.3-1.6-1.4-1.2-1.01.2-1.5-1.21.30.80.7-0.80.90.90.9-0.90.9-0.7-0.40.2-0.5
Pavlov. Cond. latency score0.60.92.3-1.31.2-1.21.2-1.1-1.5-1.3-1.1-1.01.0-1.3-0.91.00.70.7-0.70.70.70.7-0.70.7-1.0-0.20.4-0.6
Pavlov. Cond. lever contacts2.33.45.7-2.02.0-2.02.0-2.0-2.4-2.3-2.2-2.12.2-2.3-1.92.22.12.1-1.41.61.61.6-1.61.4-1.4-1.0-0.5-0.0
Pavlov. Cond. magazine entry number0.20.31.00.9-0.70.7-0.70.70.80.60.30.3-0.51.00.7-0.60.10.10.1-0.5-0.5-0.50.5-0.5-0.00.2-0.30.4
Pavlov. Cond. intertrial magazine entries0.61.32.6-0.91.1-1.11.1-1.1-0.5-1.1-0.6-0.61.0-1.6-1.41.50.40.5-1.41.61.61.6-1.60.90.9-1.4-0.80.7
Pavlov. Cond. lever-magazine prob. diff.0.71.12.3-1.51.4-1.41.4-1.4-1.5-1.3-0.9-0.91.0-1.4-1.21.10.60.5-0.70.80.80.8-0.80.8-0.6-0.30.4-0.6
Pavlov. Cond. response bias1.92.65.1-1.71.7-1.71.7-1.7-2.1-2.0-1.8-1.81.9-2.3-1.82.01.71.6-1.21.51.51.5-1.51.3-1.1-0.9-0.50.1
Time in closed arm before self-admin0.20.42.00.3-0.00.0-0.00.00.3-0.40.1-0.30.4-0.7-0.60.70.20.3-0.60.90.90.9-0.9-0.11.0-1.0-1.40.7
Time in closed arm after self-admin0.50.61.4-0.4-0.30.3-0.30.3-0.4-0.7-0.7-0.70.9-0.6-0.60.90.70.8-0.51.21.21.2-1.20.20.2-1.0-1.00.8
Time in open arm before self-admin0.50.64.6-0.5-0.10.1-0.10.1-0.9-0.1-1.0-0.50.20.21.0-0.20.60.51.1-0.7-0.7-0.70.7-0.6-2.11.10.5-0.7
Time in open arm after self-admin2.12.34.61.3-0.30.3-0.30.31.21.71.61.5-1.71.71.7-1.9-1.5-1.51.7-2.1-2.1-2.12.1-1.3-0.52.01.4-1.1
Bone: periosteal estimation0.30.83.0-1.71.7-1.71.7-1.7-0.7-0.6-0.1-0.1-0.1-0.1-0.80.6-0.3-0.4-0.60.60.60.6-0.60.30.7-0.30.5-1.0
Bone: periosteal perimeter0.51.03.4-1.71.7-1.71.7-1.9-0.7-0.7-0.1-0.20.1-0.1-1.00.70.1-0.0-0.80.80.80.8-0.80.80.9-0.60.2-0.7
Bone: post-yield work2.23.96.4-2.32.4-2.42.4-2.4-1.5-2.1-1.3-1.71.6-2.1-2.52.41.51.3-1.92.32.32.3-2.31.30.8-2.2-1.50.3
Progressive ratio test 1 active lever presses0.30.61.80.6-0.50.5-0.50.51.01.01.31.1-1.10.80.6-0.6-0.8-1.00.9-0.5-0.5-0.50.5-0.61.30.5-0.00.0
Progressive ratio test 1 breakpoint0.40.61.60.5-0.40.4-0.40.51.01.01.31.1-1.20.90.6-0.7-0.9-1.00.9-0.6-0.6-0.60.6-0.71.30.50.1-0.1
Progressive ratio test 1 inactive lever presses0.00.10.30.1-0.00.0-0.00.1-0.4-0.3-0.3-0.40.5-0.2-0.00.30.10.10.20.50.50.5-0.5-0.5-0.3-0.3-0.3-0.2
Progressive ratio test 2 active lever presses0.20.22.2-0.30.4-0.40.4-0.40.50.20.60.5-0.4-0.1-0.00.2-0.6-0.60.40.40.40.4-0.4-0.51.5-0.3-0.50.0
Progressive ratio test 2 breakpoint0.30.33.2-0.10.3-0.30.3-0.30.70.30.80.7-0.5-0.0-0.00.1-0.8-0.80.50.30.30.3-0.3-0.61.8-0.3-0.50.1
Progressive ratio test 2 inactive lever presses0.20.52.80.10.1-0.10.10.00.30.70.60.7-0.80.80.8-0.7-0.8-0.81.5-0.5-0.5-0.50.5-1.70.50.70.3-1.1
Incentive Sensitization - Responses0.20.62.3-0.30.3-0.30.3-0.40.3-0.40.0-0.10.3-1.3-0.31.1-0.4-0.3-0.21.21.21.2-1.2-0.21.5-1.0-1.20.4
Incentive Sensitization - Breakpoint0.30.62.2-0.30.4-0.40.4-0.50.2-0.50.0-0.10.3-1.3-0.41.1-0.4-0.3-0.21.21.21.2-1.2-0.21.5-1.0-1.10.4
Sum of active levers in priming session hrs 5-60.60.61.90.30.2-0.20.2-0.30.80.71.11.2-1.40.50.6-0.6-1.1-1.3-0.0-0.7-0.7-0.70.70.01.20.70.6-0.7
Progressive ratio0.10.20.7-0.20.8-0.80.8-0.80.1-0.10.10.10.1-0.2-0.50.30.10.1-0.1-0.0-0.0-0.00.0-0.80.7-0.4-0.3-0.2
Food seeking constrained by brief footshock0.50.62.90.10.0-0.00.00.1-0.6-0.7-1.2-0.90.8-0.8-0.30.81.61.7-0.90.30.30.3-0.30.7-0.7-0.6-1.21.0
Seeking ratio, punishment vs. effort0.10.31.50.2-1.21.2-1.21.2-0.20.0-0.30.0-0.1-0.30.40.10.30.4-0.10.00.00.0-0.01.1-0.30.3-0.10.6
Retroperitoneal fat weight1.35.911.03.2-3.13.1-3.13.33.22.93.02.6-3.33.12.5-2.6-1.7-1.80.3-2.1-2.1-2.12.1-0.91.91.30.60.6
Reaction time number correct0.51.93.71.9-1.81.8-1.81.91.91.71.71.5-1.70.81.6-1.0-0.9-1.01.6-1.1-1.1-1.11.1-0.90.71.0-0.40.7
Reaction time mean minus median0.00.31.4-0.0-0.40.4-0.40.40.10.30.40.7-0.00.2-0.3-0.5-1.2-1.10.3-0.2-0.2-0.20.2-0.40.40.11.1-0.7
Reaction time mean minus median AUC0.10.42.00.1-0.50.5-0.50.40.60.40.80.8-0.20.2-0.6-0.3-1.4-1.30.10.30.30.3-0.30.11.4-0.50.5-0.1
Reaction time num false alarms0.40.71.60.9-0.80.8-0.80.90.10.50.20.3-0.81.31.1-1.0-0.0-0.1-0.1-1.2-1.2-1.21.2-0.7-1.11.10.8-0.6
Reaction time num false alarms AUC0.30.61.40.9-0.80.8-0.80.80.10.50.30.3-0.61.21.1-0.9-0.2-0.20.1-1.0-1.0-1.01.0-0.9-0.90.90.7-0.7
Reaction time trials correct on left0.51.93.71.9-1.81.8-1.81.91.91.71.71.5-1.70.81.6-1.0-0.9-1.01.6-1.1-1.1-1.11.1-0.90.71.0-0.40.7
Reaction time trials on left0.62.03.81.9-1.81.8-1.81.91.91.71.81.6-1.80.81.6-1.1-0.9-1.11.6-1.1-1.1-1.11.1-0.90.71.1-0.40.7
Reaction time mean0.40.83.80.3-0.40.4-0.40.21.20.91.41.4-0.90.30.3-0.5-1.9-2.00.4-0.2-0.2-0.20.2-0.71.80.20.8-0.6
Reaction time mean AUC0.51.24.90.6-0.80.8-0.80.61.41.21.61.7-1.20.50.7-0.8-2.1-2.20.7-0.4-0.4-0.40.4-1.11.80.50.9-0.7
Median of all reaction times0.50.93.60.5-0.40.4-0.40.21.31.01.51.5-1.10.30.5-0.5-1.8-1.90.4-0.2-0.2-0.20.2-0.81.90.30.5-0.4
Reaction time omissions1.42.34.41.9-2.02.0-2.02.11.81.71.41.5-1.41.62.1-1.7-1.8-1.71.1-1.0-1.0-1.01.0-1.50.21.00.50.0
Reaction time false alarm rate0.20.21.2-0.10.1-0.10.1-0.2-0.7-0.4-0.6-0.40.20.70.2-0.30.30.3-0.7-0.4-0.4-0.40.4-0.3-1.10.30.8-0.9
Reaction time premature initiation rate0.50.92.5-0.50.8-0.80.8-0.8-0.5-0.9-0.7-1.00.8-0.8-0.91.01.31.2-1.30.90.90.9-0.91.6-0.4-0.8-0.71.1
Reaction time premature initiations0.10.21.90.7-0.30.3-0.30.30.70.30.50.1-0.4-0.20.20.30.40.4-0.30.10.10.1-0.10.90.3-0.2-0.91.4
Std. dev. reaction times0.31.14.20.7-1.01.0-1.00.91.21.11.41.5-1.00.80.6-0.9-2.0-2.10.5-0.4-0.4-0.40.4-0.71.30.41.1-0.5
Reaction time trials completed0.62.03.81.9-1.81.8-1.81.91.91.71.81.6-1.80.81.6-1.1-0.9-1.11.6-1.1-1.1-1.11.1-0.90.71.1-0.40.7
Reaction time trials AUC0.51.83.31.8-1.71.7-1.71.81.81.61.71.5-1.70.71.5-1.0-0.9-1.01.5-1.1-1.1-1.11.1-0.80.71.1-0.30.7
Run reversals in cocaine runway, females2.02.25.21.8-1.91.9-1.91.72.01.62.12.1-1.50.30.9-0.8-2.2-2.31.1-0.7-0.7-0.70.7-1.02.10.60.1-0.3
Run reversals in cocaine runway, males0.30.31.20.8-0.70.7-0.70.60.50.60.20.1-0.60.81.1-0.70.10.20.5-0.5-0.5-0.50.5-0.3-0.60.4-0.60.5
Latency to leave start box in cocaine runway6.28.614.33.7-2.82.8-2.82.83.63.73.53.7-3.82.93.6-3.0-3.3-3.32.4-2.8-2.8-2.82.8-1.61.52.61.4-0.4
Latency to leave start box in cocaine runway, F2.12.66.52.1-1.41.4-1.41.52.32.22.32.1-2.61.62.1-1.6-1.4-1.50.8-1.3-1.3-1.31.3-0.61.51.10.10.3
Latency to leave start box in cocaine runway, M5.14.97.22.5-2.12.1-2.12.12.02.52.02.5-2.22.12.5-2.3-2.7-2.52.2-2.4-2.4-2.42.4-1.5-0.12.52.1-1.1
Std. dev. time between licks in bursts1.52.95.3-2.11.8-1.81.8-1.8-2.2-2.3-1.9-2.02.1-1.7-2.01.81.01.1-1.91.71.71.7-1.70.8-0.9-1.40.2-1.0
Total sessions with >9 infusions0.30.31.5-0.81.2-1.21.2-1.10.00.20.30.2-0.40.4-0.3-0.1-0.2-0.00.6-0.1-0.1-0.10.1-0.10.90.1-0.2-0.3
Short access day 1 total inactive lever presses0.30.61.7-0.41.1-1.11.1-1.1-0.40.1-0.10.1-0.30.9-0.0-0.7-0.10.00.6-0.9-0.9-0.90.9-0.9-0.60.80.8-1.3
Short access day 10 total inactive lever presses0.10.82.4-0.81.0-1.01.0-1.0-1.5-1.0-1.1-0.91.10.1-1.00.20.70.6-0.50.30.30.3-0.3-0.3-1.40.01.2-1.5
Short access day 1 total infusions0.20.31.3-0.81.1-1.11.1-1.2-0.0-0.00.10.1-0.50.2-0.50.10.10.30.0-0.1-0.1-0.10.1-0.01.0-0.1-0.4-0.1
Short access day 10 total infusions0.40.71.90.6-0.30.3-0.30.21.11.11.41.1-1.31.30.2-1.1-0.6-0.50.5-0.8-0.8-0.80.8-0.61.40.40.00.1
Short access total infusions0.50.71.70.2-0.00.0-0.0-0.11.01.11.31.0-1.31.20.4-0.9-0.8-0.71.0-0.9-0.9-0.90.9-0.71.20.60.1-0.1
Short access day 1 locomotion0.20.30.8-0.80.7-0.70.7-0.80.10.30.40.5-0.60.5-0.3-0.3-0.6-0.40.2-0.3-0.3-0.30.3-0.40.90.20.6-0.8
Short access day 10 total locomotion0.31.22.90.9-0.70.7-0.70.71.11.41.41.4-1.31.70.3-1.5-0.9-1.11.2-1.2-1.2-1.21.2-0.91.20.70.7-0.6
Short access total locomotion0.20.31.3-0.20.3-0.30.3-0.20.40.60.90.8-0.81.0-0.3-0.7-0.5-0.50.5-0.5-0.5-0.50.5-0.31.10.30.6-0.6
One hour access (0.3 mA shock)0.10.10.3-0.20.2-0.20.20.0-0.2-0.3-0.3-0.30.4-0.0-0.50.20.10.20.10.50.50.5-0.5-0.40.3-0.5-0.30.2
Compulsive drug intake2.13.15.4-1.61.6-1.61.6-1.4-1.3-2.0-1.6-1.81.8-2.3-2.12.21.31.4-2.31.91.91.9-1.92.30.1-1.9-1.21.1
One hour access (shock baseline)0.41.12.90.9-0.80.8-0.80.80.61.20.90.9-0.91.71.0-1.5-0.5-0.61.6-1.1-1.1-1.11.1-1.7-0.11.10.7-0.6
Social response proportion0.10.20.50.1-0.50.5-0.50.7-0.3-0.3-0.5-0.40.60.4-0.1-0.30.30.30.30.40.40.4-0.4-0.7-0.2-0.3-0.20.1
Social responses0.70.92.1-1.51.4-1.41.4-1.2-1.2-1.2-1.1-0.81.3-0.6-1.10.80.40.4-0.41.01.01.0-1.00.2-0.1-0.70.4-0.7
Social time0.20.32.1-0.30.2-0.20.2-0.40.30.20.30.20.20.30.0-0.3-0.9-0.91.0-0.2-0.2-0.20.2-1.50.60.00.4-0.8
Soleus weight0.82.44.2-1.31.2-1.21.2-1.2-1.7-1.9-1.9-2.11.7-1.1-1.41.62.01.9-1.51.81.81.8-1.81.5-0.8-1.5-1.00.7
Bone: stiffness0.81.54.7-0.50.5-0.50.5-0.40.20.81.00.9-1.11.90.6-1.5-1.5-1.60.8-1.3-1.3-1.31.3-1.5-0.41.32.2-2.0
Tibialis anterior weight4.214.327.8-5.25.3-5.35.3-5.2-3.8-4.2-3.4-3.43.8-3.5-4.44.02.82.6-2.63.93.93.9-3.92.40.8-3.4-1.40.0
Time to tail flick, vehicle, before self-admin0.20.31.6-0.41.0-1.01.0-1.3-0.3-0.2-0.2-0.3-0.10.20.2-0.00.50.2-0.3-0.1-0.1-0.10.1-0.1-0.80.20.1-0.4
Time to tail flick, vehicle, after self-admin0.30.62.00.4-0.50.5-0.50.70.40.70.61.0-0.30.6-0.0-0.8-1.1-1.01.2-0.7-0.7-0.70.7-1.40.20.71.2-1.2
Time to tail flick, test, before self-admin0.60.71.3-0.50.5-0.50.5-0.6-0.7-1.1-1.0-0.90.9-1.1-0.91.00.50.4-1.21.11.11.1-1.10.80.1-1.1-0.50.2
Time to tail flick, test, after self-admin0.40.43.0-0.1-0.10.1-0.10.00.80.41.11.0-1.00.3-0.1-0.2-0.9-1.0-1.0-0.1-0.1-0.10.10.61.7-0.10.70.1
Delta time to tail flick, vehicle, before/after SA0.80.93.01.0-1.41.4-1.41.71.30.91.01.1-0.40.30.0-0.5-1.4-1.20.7-0.4-0.4-0.40.4-0.91.30.00.20.1
Delta time to tail flick, test, before/after SA1.01.24.60.6-0.60.6-0.60.51.61.32.01.8-1.81.00.5-0.9-1.5-1.4-0.1-0.9-0.9-0.90.90.12.10.50.70.3
Tibia length0.10.31.0-0.80.9-0.90.9-0.7-0.7-0.2-0.3-0.3-0.20.90.2-0.5-0.1-0.1-0.10.20.20.2-0.2-0.2-0.80.31.0-1.0
Ambulatory time before self-admin0.10.51.8-0.0-0.20.2-0.20.2-0.3-0.6-0.8-0.80.5-0.2-0.10.61.01.1-1.00.60.60.6-0.61.0-0.6-0.7-0.81.3
Ambulatory time after self-admin0.10.10.3-0.2-0.20.2-0.20.1-0.30.10.20.1-0.40.50.2-0.20.20.3-0.3-0.5-0.5-0.50.50.5-0.40.50.5-0.0
Bone: tissue strength3.84.012.7-1.81.7-1.71.7-1.8-3.0-2.5-3.1-3.12.5-1.0-1.21.42.62.5-1.91.41.41.4-1.40.4-3.6-0.60.2-1.0
Total heroin consumption3.23.75.81.1-1.21.2-1.21.11.42.11.92.0-2.32.42.1-2.4-2.1-2.41.6-2.4-2.4-2.42.4-1.3-0.42.32.4-1.7
Bone: trabecular number1.42.74.2-1.81.8-1.81.8-2.1-1.5-1.9-1.7-1.71.8-1.8-1.62.01.81.7-1.11.71.71.7-1.71.10.2-1.7-1.50.6
Bone: trabecular spacing2.84.16.62.1-2.12.1-2.12.11.62.21.81.9-2.11.92.5-2.4-1.9-1.91.7-2.2-2.2-2.22.2-2.6-0.72.41.7-1.3
Bone: trabecular thickness2.13.06.1-2.42.4-2.42.4-2.5-2.0-1.8-1.7-1.61.7-1.2-1.71.91.41.4-0.61.71.71.7-1.71.30.0-1.4-0.8-0.2
Bone: trabecular tissue density0.20.41.90.6-0.50.5-0.50.6-0.10.50.10.2-0.61.40.8-1.0-0.1-0.10.3-0.7-0.7-0.70.70.9-0.90.90.90.2
Water consumed over 24 hours0.20.31.9-0.20.2-0.20.2-0.2-0.10.30.40.5-0.50.50.5-0.3-0.8-0.80.4-0.3-0.3-0.30.3-1.00.10.60.9-1.4
Number of responses in last shaping day1.62.04.70.2-0.10.1-0.10.01.41.61.61.9-1.81.71.0-1.7-2.2-2.12.0-1.4-1.4-1.41.4-1.61.41.31.1-1.4