Mmd2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Mmd2 0.16 0.06 0.0e+00 0.21 0.19 0.2 0.21 4.4e-23 2.2e-20 4.0e-22 1.8e-22
2 Adipose isoform ratio XM_063271264.1 0.11 0.04 1.9e-14 0.13 0.11 0.1 0.11 2.5e-14 2.1e-12 6.0e-11 5.7e-12
3 Adipose alternative polyA XM_063271264.1 0.12 0.05 0.0e+00 0.17 0.15 0.14 0.15 3.2e-18 4.8e-16 5.3e-15 2.9e-16
4 Adipose alternative polyA XM_063271263.1 0.12 0.05 0.0e+00 0.17 0.15 0.14 0.15 4.1e-18 5.6e-16 7.0e-15 3.6e-16
5 Adipose isoform ratio NM_001037217.1 0.11 0.04 3.6e-14 0.13 0.11 0.1 0.1 7.0e-14 2.3e-12 1.5e-11 2.8e-11
6 BLA gene expression Mmd2 0.07 0.05 2.1e-03 0.03 0.03 0.01 0.04 9.2e-03 6.9e-03 9.6e-02 2.9e-03
7 pVTA gene expression Mmd2 0.14 0.05 1.1e-13 0.12 0.17 0.16 0.16 4.0e-10 2.2e-13 7.5e-13 3.1e-13
8 NAcc gene expression Mmd2 0.18 0.06 0.0e+00 0.2 0.2 0.19 0.2 1.5e-29 1.5e-29 2.8e-28 1.3e-29
9 PL gene expression Mmd2 0.12 0.05 1.6e-14 0.13 0.14 0.14 0.14 1.0e-13 1.4e-15 2.1e-15 1.8e-15
10 Brain gene expression Mmd2 0.36 0.09 0.0e+00 0.32 0.38 0.39 0.38 1.6e-30 6.5e-38 1.9e-38 8.1e-37
11 NAcc mRNA stability Mmd2 0.16 0.06 5.6e-17 0.13 0.12 0.12 0.13 3.5e-19 1.0e-17 2.0e-17 2.7e-19
12 Liver mRNA stability Mmd2 0.07 0.04 1.1e-05 0.03 0.04 0.04 0.04 6.5e-04 1.5e-05 3.8e-05 4.8e-05
13 PL mRNA stability Mmd2 0.14 0.05 1.3e-14 0.13 0.14 0.14 0.14 2.5e-14 1.2e-14 3.1e-15 7.8e-15
14 RMTg gene expression Mmd2 0.15 0.09 7.6e-03 0.13 0.06 0.06 0.09 2.7e-04 9.0e-03 1.1e-02 2.7e-03
15 LHb gene expression Mmd2 0.23 0.11 1.5e-03 0.11 0.08 0.1 0.1 1.2e-03 4.9e-03 2.5e-03 2.4e-03
16 OFC gene expression Mmd2 0.48 0.15 1.5e-04 0.06 0.14 0.11 0.14 1.3e-02 4.2e-04 1.3e-03 4.3e-04
17 Liver alternative polyA XM_063271263.1 0.09 0.05 1.3e-06 0.06 0.06 0.06 0.06 2.7e-07 9.7e-07 9.5e-07 4.2e-07
18 Liver gene expression Mmd2 0.34 0.12 1.1e-11 0.12 0.09 0.1 0.11 1.1e-12 3.8e-10 2.3e-11 6.8e-12
19 pVTA mRNA stability Mmd2 0.08 0.04 4.8e-05 0.07 0.05 0.06 0.05 1.9e-06 4.6e-05 1.7e-05 3.7e-05
20 Liver alternative polyA XM_063271264.1 0.1 0.05 2.4e-08 0.08 0.07 0.08 0.08 1.2e-09 9.5e-09 5.2e-09 2.2e-09
21 BLA mRNA stability Mmd2 0.14 0.07 2.9e-04 0.03 0.03 0.04 0.02 9.8e-03 6.5e-03 5.8e-03 3.8e-02
22 Eye gene expression Mmd2 0.37 0.21 9.1e-03 0.08 0.07 0.06 0.12 2.1e-02 2.8e-02 4.6e-02 6.2e-03
23 Brain mRNA stability Mmd2 0.41 0.09 0.0e+00 0.38 0.43 0.41 0.42 1.2e-36 1.5e-43 4.9e-41 1.1e-42
24 Liver intron excision ratio chr12_17076470_17077124 0.08 0.03 1.1e-07 0.01 0.06 0.06 0.05 1.3e-02 1.6e-07 1.9e-07 1.6e-06
25 Liver intron excision ratio chr12_17076470_17106372 0.05 0.03 1.2e-04 0.02 0.03 0.03 0.05 8.8e-04 6.2e-04 2.8e-04 5.0e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25
Bone: apparent density1.22.13.41.7-1.7-1.71.81.8-1.4-1.6-1.6-1.6-1.5-1.4-1.1-1.7-1.6-1.5-0.5-1.6-1.6-1.61.6-0.9-0.2-1.3-1.30.3
Area under the delay curve2.02.35.0-1.71.51.5-1.4-1.41.31.81.21.31.61.92.21.81.41.51.71.61.61.6-1.61.4-0.61.60.9-0.5
BMI with tail0.31.02.91.5-1.5-1.51.41.4-1.7-1.0-1.1-1.1-0.9-0.4-0.4-0.4-0.7-0.9-0.2-0.4-0.4-0.40.4-0.0-1.70.30.9-1.2
BMI without tail1.03.28.82.5-2.8-2.82.82.8-2.9-1.7-1.8-1.6-1.4-0.2-1.1-0.1-1.0-1.0-0.8-0.1-0.1-0.10.1-0.2-3.00.62.2-2.4
Body weight1.35.512.73.4-3.2-3.23.03.0-3.6-2.7-3.1-2.9-2.30.1-1.9-0.9-2.6-2.6-2.0-1.6-1.6-1.61.6-1.5-2.6-0.71.1-1.3
Weight adjusted by age2.13.311.01.8-1.6-1.61.51.5-1.5-1.9-1.3-1.8-1.4-1.7-2.1-2.1-2.3-1.9-2.7-1.6-1.6-1.61.6-3.30.2-1.7-1.01.6
Bone surface2.03.66.12.2-2.3-2.32.42.4-1.6-2.1-1.6-1.7-1.6-1.9-1.8-2.5-1.7-1.6-1.6-2.0-2.0-2.02.0-2.00.5-2.0-1.70.9
Bone volume2.64.67.02.5-2.6-2.62.62.6-2.0-2.4-2.1-2.2-2.1-2.2-2.0-2.6-2.0-2.0-1.6-2.2-2.2-2.22.2-1.9-0.0-2.1-1.70.7
Breakpoint value in progressive ratio session1.41.73.4-0.60.40.4-0.5-0.50.81.41.21.21.61.81.31.70.91.21.31.91.91.9-1.90.5-0.51.91.4-1.0
Number of licking bursts0.71.23.71.9-1.8-1.81.81.8-0.9-1.0-0.2-0.3-0.5-0.8-1.2-1.00.40.4-0.3-0.9-0.9-0.90.90.61.0-0.70.3-1.6
Context. condit. distance diff. score0.91.12.31.2-1.3-1.31.41.4-1.4-1.3-1.5-1.4-1.4-0.9-1.1-0.7-1.2-1.3-0.3-0.4-0.4-0.40.4-0.6-0.6-0.8-0.40.0
Locomotion velocity, session 11.01.03.9-1.31.21.2-1.5-1.52.01.01.10.90.70.40.70.20.50.50.30.40.40.4-0.40.31.7-0.5-1.21.6
Locomotion distance, session 10.50.62.4-1.00.90.9-1.0-1.01.60.81.10.90.7-0.60.5-0.30.50.50.00.10.10.1-0.10.21.3-0.3-1.11.2
Locomotion velocity, session 20.20.21.1-0.50.40.4-0.5-0.51.00.40.60.30.4-0.20.5-0.30.30.10.0-0.1-0.1-0.10.10.10.5-0.1-0.91.1
Locomotion distance, session 20.71.02.5-0.70.60.6-0.8-0.81.31.21.41.41.20.01.20.41.41.51.10.80.80.8-0.81.60.51.00.3-0.6
Locomotion velocity, session 30.81.01.9-1.21.21.2-1.4-1.40.91.00.40.40.81.21.21.20.30.30.91.21.21.2-1.20.9-0.81.00.4-0.1
Locomotion distance, session 30.20.21.3-0.30.40.4-0.4-0.4-0.00.1-0.4-0.4-0.2-0.00.2-0.0-0.8-0.80.40.00.00.0-0.00.0-1.10.1-0.40.6
Stereotopy head waving bouts, day 30.50.52.40.2-0.1-0.1-0.0-0.0-0.4-0.9-0.9-0.8-0.8-1.3-0.3-1.1-0.7-0.7-1.6-0.7-0.7-0.70.7-1.0-0.4-0.7-0.60.6
Stereotopy head waving duration, day 30.10.10.4-0.40.50.5-0.5-0.50.40.10.20.20.4-0.10.30.20.30.3-0.60.50.50.5-0.5-0.30.20.20.20.0
Locomotion velocity, session 70.80.91.6-0.40.40.4-0.6-0.61.01.21.11.11.31.00.91.00.91.01.31.31.31.3-1.31.00.41.10.5-0.4
Locomotion distance, session 71.21.53.3-0.30.20.2-0.3-0.30.71.41.31.31.51.41.21.31.11.11.71.51.51.5-1.51.4-0.11.81.3-1.1
Stereotopy head waving bouts, day 70.91.02.80.9-0.9-0.90.90.9-1.4-1.3-1.7-1.3-1.5-1.1-1.0-0.9-1.2-1.1-0.9-0.4-0.4-0.40.4-0.8-1.3-0.5-0.1-0.1
Stereotopy head waving duration, day 70.20.21.30.2-0.0-0.00.10.1-0.6-0.4-0.8-0.5-0.8-0.4-0.4-0.1-0.4-0.30.10.30.30.3-0.30.2-1.10.10.3-0.4
Locomotion velocity, session 80.30.42.70.3-0.2-0.20.30.3-0.2-0.6-0.5-0.6-0.8-1.7-0.4-1.2-0.5-0.6-0.0-0.6-0.6-0.60.6-0.10.0-0.6-1.00.8
Locomotion distance, session 80.10.20.80.5-0.5-0.50.50.5-0.5-0.5-0.7-0.6-0.6-0.9-0.0-0.7-0.5-0.60.0-0.0-0.0-0.00.00.5-0.60.0-0.3-0.2
Degree of sensitization distance0.40.51.80.2-0.3-0.30.20.20.60.61.21.11.00.50.20.31.21.20.20.40.40.4-0.40.41.30.50.6-0.6
Degree of sensitization stereotypy1.31.43.61.2-1.1-1.11.21.2-1.7-1.5-1.9-1.6-1.8-1.3-1.4-1.1-1.5-1.4-0.6-0.6-0.6-0.60.6-0.9-1.4-0.6-0.2-0.1
Conditioned locomotion0.60.71.41.0-1.1-1.11.21.2-0.9-1.0-0.8-0.7-1.0-1.0-0.9-1.0-0.4-0.4-0.7-0.9-0.9-0.90.9-0.60.2-0.8-0.4-0.2
Cocaine response after cond. corrected0.50.61.7-1.21.21.2-1.3-1.31.30.70.80.70.5-0.20.6-0.00.20.30.30.20.20.2-0.20.60.90.0-1.00.8
Cocaine response after cond. not corrected0.30.30.9-0.90.90.9-0.9-0.90.90.50.60.60.3-0.40.60.00.40.50.2-0.0-0.0-0.00.00.70.50.1-0.60.3
Cocaine response before conditioning0.30.41.60.7-0.8-0.80.80.8-0.9-0.4-0.4-0.2-0.3-0.1-0.20.10.30.30.2-0.3-0.3-0.30.30.5-1.10.51.1-1.3
Saline control response2.53.47.52.7-2.7-2.72.72.7-2.5-2.0-1.7-1.5-1.8-1.3-2.5-1.5-1.0-1.1-1.5-1.5-1.5-1.51.5-1.2-0.9-0.90.9-1.1
Bone: connectivity density0.71.12.61.4-1.3-1.31.61.6-0.7-1.0-0.6-0.6-0.8-1.1-1.0-1.6-0.7-0.6-0.3-1.1-1.1-1.11.1-0.50.9-1.0-1.10.1
Bone: cortical apparent density1.62.24.81.2-1.3-1.31.31.3-2.1-1.8-2.2-1.9-1.8-0.9-1.0-1.2-1.9-1.9-1.3-1.2-1.2-1.21.2-2.0-1.4-1.0-0.40.5
Bone: cortical area0.81.24.32.1-2.0-2.02.02.0-1.4-1.0-0.7-0.5-0.3-0.3-0.9-0.6-0.2-0.2-0.8-0.7-0.7-0.70.7-0.8-0.1-0.20.8-1.2
Bone: cortical porosity0.20.20.90.2-0.2-0.20.30.3-0.4-0.0-0.3-0.3-0.1-0.20.30.4-0.1-0.10.90.60.60.6-0.60.8-0.80.80.4-0.7
Bone: cortical porosity0.20.20.60.6-0.7-0.70.80.8-0.6-0.5-0.5-0.6-0.5-0.7-0.3-0.3-0.6-0.60.3-0.0-0.0-0.00.00.0-0.70.1-0.1-0.3
Bone: cortical thickness0.50.82.31.4-1.3-1.31.31.3-1.5-0.8-0.9-0.7-0.40.0-0.3-0.1-0.6-0.6-0.6-0.2-0.2-0.20.2-0.6-1.20.41.2-1.1
Bone: cortical thickness0.40.41.81.1-1.3-1.31.11.1-0.9-0.5-0.4-0.3-0.2-0.1-0.5-0.0-0.3-0.3-0.7-0.2-0.2-0.20.2-0.6-0.3-0.10.7-0.5
Bone: cortical tissue density1.72.35.11.2-1.3-1.31.31.3-2.2-1.9-2.3-2.0-1.9-0.9-1.1-1.3-2.0-2.0-1.3-1.2-1.2-1.21.2-2.0-1.5-1.0-0.50.5
Condit. Reinf. active minus inactive responses0.10.10.6-0.30.20.2-0.2-0.20.60.60.70.50.7-0.20.7-0.00.30.30.40.20.20.2-0.20.10.10.3-0.40.2
Condit. Reinf. active-inactive response ratio0.50.61.7-0.80.60.6-0.5-0.51.11.01.21.01.30.41.00.40.60.70.40.70.70.7-0.70.00.80.5-0.20.3
Condit. Reinf. active responses0.20.30.60.7-0.7-0.70.80.8-0.00.20.60.40.6-0.20.3-0.20.70.70.60.20.20.2-0.20.4-0.40.60.5-0.7
Condit. Reinf. inactive responses0.50.62.01.4-1.3-1.31.31.3-0.9-0.4-0.1-0.2-0.2-0.3-0.4-0.20.50.40.5-0.0-0.0-0.00.00.5-1.00.61.1-1.4
Incentive salience index mean0.20.31.1-0.20.10.1-0.1-0.10.60.70.90.61.00.31.00.40.50.50.60.50.50.5-0.50.7-0.30.70.1-0.3
Condit. Reinf. lever presses0.10.20.80.7-0.7-0.70.60.6-0.3-0.00.0-0.10.40.10.4-0.10.10.10.30.10.10.1-0.10.7-0.90.60.2-0.8
Condit. Reinf. active minus inactive responses0.70.82.31.3-1.2-1.21.21.2-1.3-1.2-1.1-1.0-1.1-1.5-0.6-0.8-0.7-0.6-0.3-0.5-0.5-0.50.50.1-1.10.00.4-0.8
Condit. Reinf. active-inactive response ratio0.50.61.21.1-1.0-1.01.11.1-0.9-0.9-0.9-0.8-1.0-1.1-0.9-0.6-0.7-0.7-0.1-0.5-0.5-0.50.5-0.2-0.3-0.4-0.0-0.2
Condit. Reinf. active responses1.01.43.51.4-1.5-1.51.51.5-1.7-1.5-1.5-1.4-1.5-1.9-0.9-1.3-1.0-0.9-0.4-0.8-0.8-0.80.8-0.2-1.3-0.30.1-0.7
Condit. Reinf. inactive responses0.40.51.20.3-0.4-0.40.30.3-1.0-0.9-1.1-1.0-1.0-1.0-0.3-1.0-0.9-0.9-0.6-0.5-0.5-0.50.5-0.4-1.1-0.2-0.3-0.0
Condit. Reinf. lever presses1.41.94.31.6-1.7-1.71.71.7-2.1-1.8-1.7-1.5-1.6-2.1-1.4-1.6-1.3-1.3-0.7-1.0-1.0-1.01.0-0.4-1.3-0.40.1-0.7
Condit. Reinf. lever reinforcers received1.01.43.41.4-1.4-1.41.41.4-1.8-1.5-1.5-1.3-1.6-1.9-1.0-1.2-0.9-0.9-0.3-0.8-0.8-0.80.8-0.1-1.4-0.20.3-0.9
Conditioned reinforcement - actives0.40.63.41.3-1.3-1.31.11.1-1.0-0.3-0.5-0.1-0.10.5-0.30.30.20.20.6-0.0-0.0-0.00.00.9-0.10.41.3-1.9
Conditioned reinforcement - inactives0.10.21.0-0.1-0.3-0.30.20.2-0.4-0.3-0.7-0.6-0.4-0.10.4-0.2-0.1-0.20.3-0.2-0.2-0.20.21.0-1.00.1-0.1-0.6
Conditioned locomotion0.70.94.21.5-1.5-1.51.31.3-1.1-0.2-0.3-0.00.00.7-0.30.50.20.10.50.40.40.4-0.40.5-0.70.81.8-2.1
Patch foraging indifference point 0 sec0.10.20.9-0.0-0.0-0.00.10.10.3-0.00.60.40.4-0.5-0.2-0.40.80.9-0.6-0.5-0.5-0.50.5-0.30.9-0.30.2-0.3
Patch foraging indifference point AUC2.53.65.92.4-2.3-2.32.32.3-2.3-2.4-1.9-1.9-2.1-1.7-2.4-1.8-1.2-1.3-2.2-1.9-1.9-1.91.9-1.8-0.7-1.60.3-0.5
Delay disc. indifference point, 0s delay0.20.20.7-0.70.80.8-0.8-0.80.40.10.0-0.10.1-0.30.2-0.2-0.2-0.1-0.2-0.3-0.3-0.30.3-0.20.1-0.4-0.70.8
Delay disc. indifference point, 16s delay3.63.96.2-2.21.91.9-1.8-1.81.82.41.72.11.92.32.52.32.32.12.22.12.12.1-2.12.1-0.02.01.4-0.9
Delay disc. indifference point, 2s delay0.10.10.4-0.30.20.2-0.1-0.10.30.10.20.00.3-0.30.2-0.0-0.10.2-0.50.00.00.0-0.0-0.60.1-0.2-0.20.5
Delay disc. indifference point, 24s delay0.50.61.7-0.80.90.9-0.7-0.71.21.01.01.00.80.20.90.31.31.30.70.30.30.3-0.30.41.30.1-0.20.3
Delay disc. indifference point, 4s delay2.02.14.0-1.91.71.7-1.6-1.61.31.71.31.11.52.01.91.70.81.01.11.61.61.6-1.60.9-0.81.40.60.1
Delay disc. indifference point, 8s delay2.22.56.1-1.61.51.5-1.5-1.51.11.81.01.11.52.12.52.01.01.22.01.91.91.9-1.91.5-1.31.80.8-0.5
Indifference point function ln k2.03.66.9-2.42.32.3-2.3-2.32.22.31.91.92.01.62.51.71.41.52.61.71.71.7-1.71.60.81.5-0.40.3
Indifference point function log k2.03.66.9-2.42.32.3-2.3-2.32.22.31.91.92.01.62.51.71.41.52.61.71.71.7-1.71.60.81.5-0.40.3
Patch foraging total patch changes 0 sec0.20.31.7-0.50.40.4-0.3-0.30.70.30.90.80.7-0.20.1-0.11.01.2-0.3-0.3-0.3-0.30.3-0.21.3-0.20.1-0.2
Patch foraging total patch changes 12 sec1.82.36.41.7-1.5-1.51.51.5-1.3-1.8-0.9-1.0-1.3-1.5-2.2-1.7-0.5-0.6-2.5-1.9-1.9-1.91.9-1.50.8-1.8-0.1-0.1
Patch foraging total patch changes 18 sec0.81.22.81.4-1.5-1.51.31.3-1.1-1.2-0.8-0.8-0.9-1.1-1.7-0.9-0.5-0.4-1.5-1.1-1.1-1.11.1-1.10.3-1.10.4-0.4
Patch foraging total patch changes 24 sec1.22.15.21.6-1.5-1.51.41.4-1.9-1.9-1.5-1.6-1.4-1.3-1.9-1.5-1.2-1.0-2.3-1.4-1.4-1.41.4-1.7-0.8-1.20.3-0.5
Patch foraging total patch changes 6 sec0.50.82.11.2-1.0-1.01.01.0-1.1-1.0-0.3-0.2-0.5-0.8-1.4-0.80.40.4-1.4-0.8-0.8-0.80.8-0.30.4-0.51.1-1.4
Patch foraging time to switch 0 sec0.61.12.3-0.60.90.9-1.0-1.01.31.21.31.41.30.90.41.00.90.90.91.41.41.4-1.41.50.90.80.1-0.1
Patch foraging water rate 0 sec0.30.51.30.4-0.8-0.80.80.8-0.8-0.7-0.7-0.8-0.6-0.7-0.2-0.7-0.5-0.5-0.5-1.1-1.1-1.11.1-0.9-0.4-0.5-0.20.1
Patch foraging water rate 12 sec0.81.64.20.4-1.0-1.00.80.8-0.6-1.1-1.2-1.4-0.9-1.7-0.5-1.7-1.7-1.6-0.8-1.3-1.3-1.31.3-1.70.0-1.2-2.11.7
Patch foraging water rate 18 sec0.00.00.4-0.1-0.2-0.20.20.2-0.00.20.10.00.3-0.00.5-0.0-0.0-0.10.60.00.00.0-0.0-0.0-0.00.3-0.40.1
Patch foraging water rate 24 sec0.91.32.70.9-0.8-0.80.80.8-0.6-1.0-0.8-1.0-0.9-1.4-0.9-1.5-0.7-0.7-0.5-1.7-1.7-1.71.7-1.20.9-1.4-1.40.9
Patch foraging water rate 6 sec0.20.31.2-0.2-0.2-0.20.00.00.10.50.30.10.51.01.10.70.10.20.40.40.40.4-0.4-0.1-1.00.80.7-0.1
Seeking ratio, delayed vs. immediate footshock0.20.31.00.6-0.9-0.91.01.0-0.3-0.2-0.00.20.10.0-0.40.00.30.3-0.4-0.0-0.0-0.00.00.20.10.20.8-1.0
Distance traveled before self-admin0.10.21.2-0.50.70.7-0.7-0.70.40.2-0.1-0.00.20.20.5-0.1-0.2-0.3-0.3-0.0-0.0-0.00.0-0.3-0.2-0.2-0.61.1
Distance traveled after self-admin0.20.20.6-0.10.30.3-0.3-0.3-0.00.30.30.30.50.70.30.3-0.2-0.1-0.20.80.80.8-0.8-0.5-0.40.70.50.1
Extensor digitorum longus weight1.76.913.43.7-3.6-3.63.63.6-3.0-3.0-2.7-2.8-2.7-2.1-3.0-2.5-2.5-2.4-1.9-2.4-2.4-2.42.4-1.9-0.4-2.1-1.0-0.1
Bone: elastic displacement2.52.96.40.5-0.4-0.40.60.6-1.4-1.8-2.3-2.1-1.9-2.5-1.0-2.0-2.5-2.5-1.9-1.8-1.8-1.81.8-2.0-0.8-1.4-1.81.5
Bone: elastic work2.93.86.11.9-1.8-1.82.02.0-2.2-2.3-2.3-2.2-1.8-2.1-1.4-1.8-2.1-2.0-2.5-2.2-2.2-2.22.2-2.4-1.1-1.4-0.50.3
Bone: endosteal estimation0.10.20.90.7-0.9-0.90.90.9-0.0-0.20.10.10.20.1-0.4-0.40.40.4-0.3-0.3-0.3-0.30.30.10.9-0.4-0.1-0.4
Bone: endosteal perimeter0.40.93.91.0-1.1-1.11.21.20.0-0.50.20.1-0.2-0.8-1.1-1.10.20.3-0.5-1.2-1.2-1.21.2-0.22.0-1.2-0.7-0.3
Epididymis fat weight0.62.06.0-2.42.32.3-2.4-2.41.91.10.90.71.10.81.20.6-0.3-0.3-0.0-0.4-0.4-0.40.4-0.01.2-0.4-2.02.1
Delta time in closed arm before/after self-admin0.90.94.32.1-1.0-1.00.90.9-1.7-1.0-1.2-0.7-1.0-0.3-0.7-0.6-0.4-0.40.1-0.4-0.4-0.40.4-0.2-0.80.11.3-1.4
Delta time in open arm before/after self-admin3.23.27.3-2.41.01.0-0.8-0.82.52.42.72.42.41.91.52.12.22.11.31.81.81.8-1.80.91.41.30.6-0.0
Diff in mean of infusions in LGA sessions1.41.83.3-0.40.80.8-0.5-0.50.91.61.61.61.51.70.71.71.61.71.51.61.61.6-1.60.80.21.41.8-1.2
Delay discount exponential model param2.52.75.91.8-1.6-1.61.51.5-1.4-1.9-1.3-1.5-1.7-2.1-2.4-2.0-1.5-1.7-1.8-1.8-1.8-1.81.8-1.60.7-1.7-1.10.7
Extinction: sum of active levers before priming0.30.41.61.2-1.2-1.21.31.3-0.4-0.3-0.2-0.2-0.10.3-0.3-0.1-0.3-0.1-0.40.00.00.0-0.0-0.6-0.1-0.10.5-0.2
Active lever presses in extinction session 60.60.61.80.6-0.4-0.40.40.40.3-0.50.0-0.2-0.1-0.9-0.7-1.0-0.5-0.3-1.3-0.8-0.8-0.80.8-1.31.1-1.1-1.21.3
Bone: final force1.22.05.72.3-2.3-2.32.42.4-1.9-1.1-1.1-0.9-0.30.6-0.60.2-0.10.0-0.8-0.2-0.2-0.20.2-0.1-1.70.52.1-2.3
Bone: final moment1.32.16.02.3-2.3-2.32.42.4-2.1-1.2-1.3-1.0-0.50.6-0.50.2-0.3-0.1-0.7-0.1-0.1-0.10.10.0-2.00.62.2-2.4
Food consumed during 24 hour testing period0.10.20.6-0.20.10.1-0.0-0.00.40.30.70.70.40.30.0-0.10.80.8-0.0-0.0-0.0-0.00.00.50.70.20.3-0.5
Glucose1.72.86.2-2.32.52.5-2.1-2.12.22.12.01.92.01.81.71.71.11.10.71.11.11.1-1.10.51.60.90.10.6
Heart weight0.30.41.1-0.81.01.0-1.1-1.10.70.70.50.40.70.60.90.6-0.1-0.00.10.50.50.5-0.5-0.1-0.30.3-0.30.8
Delay discount hyperbolic model param1.61.84.11.6-1.3-1.31.21.2-1.1-1.6-1.0-1.1-1.4-1.7-2.0-1.6-1.2-1.4-1.4-1.5-1.5-1.51.5-1.30.7-1.4-0.90.5
Intermittent access intake day 1-15 change0.20.42.40.2-0.4-0.40.20.2-0.50.2-0.4-0.30.21.10.60.8-0.5-0.60.30.80.80.8-0.80.5-1.50.90.8-0.6
Intermittent access intake escalation0.20.41.10.4-0.6-0.60.50.5-0.40.2-0.2-0.10.31.00.40.7-0.3-0.40.40.70.70.7-0.70.5-1.10.80.7-0.7
Intermittent access intake escalation 20.20.20.80.3-0.4-0.40.20.2-0.40.0-0.3-0.10.00.90.10.6-0.5-0.50.30.60.60.6-0.60.3-0.90.50.5-0.3
Intermitt. access day 1 inactive lever presses0.00.10.3-0.1-0.0-0.0-0.1-0.1-0.4-0.1-0.2-0.0-0.40.3-0.10.10.00.00.3-0.1-0.1-0.10.10.1-0.50.20.4-0.5
Intermitt. access day 15 inactive lever presses0.10.30.80.7-0.8-0.80.60.6-0.7-0.4-0.5-0.7-0.6-0.0-0.3-0.1-0.6-0.7-0.1-0.1-0.1-0.10.10.3-0.9-0.00.2-0.6
Intermitt. access escalation Index0.50.74.1-0.30.40.4-0.3-0.30.3-0.3-0.2-0.2-0.5-1.1-0.5-0.9-0.6-0.5-0.5-0.9-0.9-0.90.9-1.00.8-1.1-1.62.0
Intermittent access day 1 total infusions0.20.40.9-0.20.20.2-0.1-0.10.60.80.90.80.91.00.20.80.70.60.60.60.60.6-0.60.60.90.50.4-0.4
Intermittent access day 15 total infusions0.20.41.5-0.0-0.2-0.20.10.10.40.70.70.60.81.20.20.90.20.00.70.80.80.8-0.80.70.30.60.3-0.1
Intermittent access terminal intake (last 3 days)0.10.20.7-0.30.10.1-0.1-0.10.60.60.70.50.60.80.00.60.0-0.10.40.40.40.4-0.40.40.70.1-0.30.5
Intermittent access total infusions0.60.71.6-0.80.60.6-0.5-0.51.01.11.21.01.11.30.61.10.60.50.90.90.90.9-0.90.90.80.60.10.2
Intermittent access day 1 locomotion0.30.41.10.1-0.1-0.10.10.10.40.70.90.80.71.0-0.10.90.60.70.80.60.60.6-0.60.50.70.60.7-0.7
Intermittent access day 15 total locomotion0.20.41.10.9-1.0-1.01.01.0-0.60.00.10.10.20.8-0.60.6-0.3-0.20.10.50.50.5-0.50.2-0.10.41.0-1.0
Intermittent access total locomotion0.30.31.2-0.0-0.1-0.10.10.10.30.60.80.80.71.1-0.10.90.40.50.30.70.70.7-0.70.20.60.50.9-0.5
Intermittent access standard deviation0.61.23.4-1.21.21.2-1.2-1.20.71.10.50.40.81.81.31.60.20.01.11.31.31.3-1.31.2-1.11.20.5-0.0
Left kidney weight0.20.92.61.4-1.6-1.61.61.6-1.2-0.8-1.0-0.9-0.60.6-0.60.0-0.8-0.7-0.4-0.9-0.9-0.90.9-0.90.0-0.60.2-0.3
Right kidney weight0.31.33.01.3-1.3-1.31.21.2-0.7-0.8-0.5-0.7-0.4-0.1-0.9-0.7-0.6-0.6-1.0-1.7-1.7-1.71.7-1.61.0-1.3-0.60.6
Cocaine induced anxiety0.10.20.4-0.4-0.0-0.00.10.10.30.50.40.60.60.40.60.60.50.50.40.50.50.5-0.5-0.20.10.60.6-0.1
Post-drug Anxiety0.30.31.40.1-0.6-0.60.60.6-0.10.30.10.30.50.60.40.70.40.40.20.80.80.8-0.8-0.3-0.70.91.2-0.6
Baseline Anxiety0.10.10.70.3-0.2-0.20.10.1-0.2-0.1-0.1-0.10.10.30.10.20.10.2-0.00.40.40.4-0.40.3-0.80.50.7-0.8
Tail length1.66.313.43.4-3.3-3.33.33.3-3.7-3.1-3.3-2.9-2.6-0.6-2.4-1.3-2.6-2.5-2.9-1.7-1.7-1.71.7-2.2-2.1-1.40.9-0.9
Length with tail0.94.08.92.9-2.5-2.52.42.4-3.0-2.3-3.0-2.6-2.00.5-1.6-0.6-2.4-2.4-1.9-1.4-1.4-1.41.4-1.6-1.9-0.90.7-0.8
Length without tail0.30.81.71.2-0.7-0.70.50.5-0.9-0.9-1.2-1.2-0.80.7-0.8-0.3-1.3-1.3-1.1-1.1-1.1-1.11.1-1.0-0.1-0.9-0.20.3
Times rat made contact with spout0.00.00.2-0.10.00.00.00.0-0.3-0.0-0.3-0.1-0.20.50.40.1-0.1-0.10.4-0.0-0.0-0.00.00.3-0.20.10.2-0.2
Lifetime Intake0.60.71.7-0.50.20.2-0.1-0.10.91.11.21.01.21.30.61.10.80.61.11.01.01.0-1.01.10.80.80.3-0.2
Liver weight, left0.20.30.90.8-0.8-0.80.80.8-0.6-0.4-0.5-0.6-0.10.7-0.30.3-0.9-0.9-0.20.40.40.4-0.4-0.2-0.70.00.0-0.2
Liver weight, right0.20.41.60.9-1.0-1.01.11.1-0.8-0.4-0.3-0.2-0.30.4-0.50.10.0-0.0-0.10.10.10.1-0.10.2-0.20.31.2-1.3
Locomotor activity0.61.02.81.2-1.2-1.20.90.9-1.7-1.3-1.5-1.3-1.3-0.4-0.9-0.4-1.1-1.1-0.5-0.8-0.8-0.80.8-0.0-1.1-0.30.6-0.7
Locomotor testing distance0.40.71.61.0-1.3-1.31.11.1-1.3-0.9-1.2-0.9-0.9-0.1-0.6-0.1-0.9-0.8-0.1-0.3-0.3-0.30.30.3-1.0-0.00.5-0.8
Locomotor testing rearing1.22.47.62.7-2.6-2.62.42.4-2.1-1.8-1.5-1.5-1.5-0.7-2.1-0.9-0.9-0.9-0.7-0.8-0.8-0.80.8-0.2-0.9-0.60.9-1.4
Locomotion in novel chamber0.10.10.90.40.20.2-0.2-0.2-0.3-0.0-0.00.3-0.10.3-0.30.20.50.40.2-0.0-0.0-0.00.00.30.4-0.10.6-0.9
Locomotion in novel chamber post-restriction0.40.73.10.00.40.4-0.4-0.4-0.1-0.5-0.5-0.6-0.8-1.2-0.7-1.0-1.1-1.0-0.3-0.9-0.9-0.90.9-0.70.7-1.0-1.81.3
Fecal boli incidents, locomotor time 10.40.61.31.1-0.7-0.70.50.5-1.1-0.9-1.1-1.0-1.1-0.6-1.1-0.7-0.8-0.8-0.3-0.7-0.7-0.70.7-0.4-0.7-0.60.2-0.4
Change in fecal boli incidents, locomotor task0.10.10.2-0.10.30.3-0.3-0.30.00.10.20.10.20.30.10.3-0.0-0.1-0.30.40.40.4-0.40.3-0.40.40.4-0.1
Time >=10cm from walls, locomotor time 11.01.12.70.20.50.5-0.5-0.5-0.6-1.1-1.1-1.1-1.1-1.6-0.8-1.4-1.2-1.3-1.5-1.2-1.2-1.21.2-0.8-0.3-1.2-1.21.0
Bouts of movement, locomotor time 10.80.92.80.4-0.8-0.80.50.50.20.80.70.81.11.10.81.11.11.11.41.01.01.0-1.01.00.11.11.3-1.7
Total resting periods, locomotor time 10.70.83.00.6-0.8-0.80.50.5-0.00.70.60.70.90.90.61.01.01.01.30.90.90.9-0.90.80.21.01.4-1.7
Rest time, locomotor task time 10.40.51.71.3-1.2-1.20.80.8-0.30.10.40.50.40.6-0.70.60.60.70.60.40.40.4-0.40.20.70.21.3-1.2
Distance moved, locomotor task time 10.60.83.8-2.01.51.5-1.5-1.50.60.1-0.2-0.3-0.2-0.31.0-0.3-0.7-0.7-0.9-0.2-0.2-0.20.2-0.4-0.8-0.2-1.41.5
Vertical activity count, locomotor time 10.10.43.9-0.40.30.3-0.1-0.1-0.7-0.4-0.9-0.7-0.9-0.20.5-0.1-0.5-0.50.2-0.1-0.1-0.10.10.8-2.00.4-0.0-0.5
Time >=10cm from walls, locomotor time 20.81.25.2-0.80.90.9-1.0-1.00.3-0.4-0.3-0.8-0.1-1.1-0.1-0.9-1.7-1.6-1.8-0.7-0.7-0.70.7-1.6-0.1-1.1-1.82.3
Bouts of movement, locomotor time 20.10.10.3-0.20.40.4-0.6-0.6-0.2-0.1-0.3-0.30.10.00.40.1-0.5-0.5-0.1-0.1-0.1-0.10.1-0.5-0.3-0.2-0.50.2
Total resting periods, locomotor time 20.00.10.30.10.20.2-0.4-0.4-0.30.1-0.2-0.10.30.20.50.3-0.1-0.10.20.20.20.2-0.2-0.0-0.30.20.1-0.5
Rest time, locomotor task time 21.31.77.71.1-0.7-0.70.40.4-0.30.60.71.10.91.2-0.11.41.61.61.31.31.31.3-1.31.40.01.42.8-2.7
Distance moved, locomotor task time 21.01.25.4-2.11.31.3-1.3-1.30.8-0.0-0.2-0.7-0.3-0.21.0-0.5-1.1-1.0-1.5-0.6-0.6-0.60.6-0.8-0.3-0.9-2.12.3
Vertical activity count, locomotor time 21.42.04.60.2-0.4-0.40.40.4-1.4-1.6-1.9-2.1-1.9-1.2-0.7-1.4-2.1-2.0-1.4-1.5-1.5-1.51.5-0.9-1.7-1.3-1.51.2
Light reinforcement 11.53.67.22.3-2.3-2.32.02.0-2.2-2.3-2.0-1.9-1.8-2.2-2.1-2.0-1.5-1.5-2.7-1.8-1.8-1.81.8-1.9-0.5-1.60.1-0.2
Light reinforcement 20.71.02.20.1-0.3-0.30.30.3-0.7-1.0-1.1-1.2-1.1-1.5-0.4-1.2-1.1-1.2-1.0-1.3-1.3-1.31.3-1.3-0.4-1.1-1.31.1
Bone: marrow area0.10.30.90.7-0.9-0.90.90.90.0-0.30.10.10.10.0-0.4-0.40.40.3-0.3-0.3-0.3-0.30.30.11.0-0.5-0.1-0.3
Bone: maximum diameter0.40.71.51.1-1.2-1.21.21.2-0.2-0.6-0.1-0.1-0.2-0.7-0.7-1.0-0.0-0.1-0.8-0.9-0.9-0.90.9-0.91.2-0.9-0.6-0.0
Bone: maximum force1.01.85.72.4-2.4-2.42.42.4-1.7-1.2-0.9-0.9-0.5-0.1-1.0-0.3-0.2-0.0-1.2-0.5-0.5-0.50.5-0.2-0.8-0.11.5-1.9
Bone: maximum moment1.01.85.32.3-2.3-2.32.32.3-1.9-1.2-1.1-1.0-0.50.0-0.8-0.2-0.4-0.2-1.0-0.5-0.5-0.50.5-0.0-1.20.11.5-2.0
Mean time between licks in bursts0.10.31.20.4-0.3-0.30.30.3-0.8-0.6-0.6-0.5-0.5-0.10.1-0.0-0.1-0.2-0.9-0.5-0.5-0.50.5-0.4-1.1-0.00.6-0.7
Mean num. licks in bursts0.71.13.3-1.81.71.7-1.6-1.60.61.00.00.40.41.31.41.2-0.3-0.30.80.90.90.9-0.90.1-1.11.00.11.0
Cd content in liver1.51.64.6-0.80.80.8-0.8-0.80.91.31.41.51.41.41.21.11.51.61.81.31.31.3-1.32.20.11.61.0-1.2
Co content in liver0.60.73.90.0-0.1-0.10.10.1-0.60.1-0.30.00.20.70.60.30.20.20.81.01.01.0-1.01.7-2.01.51.0-1.7
Cu content in liver0.20.21.6-0.70.60.6-0.8-0.80.40.50.20.10.1-0.00.40.2-0.1-0.11.30.10.10.1-0.10.1-0.30.2-0.60.4
Fe content in liver1.51.93.81.0-0.9-0.90.70.7-0.5-1.2-0.9-1.2-1.1-1.7-1.5-1.6-1.4-1.4-1.3-1.6-1.6-1.61.6-1.91.1-1.9-2.01.6
K content in liver0.40.42.7-0.70.60.6-0.6-0.60.60.70.50.50.21.00.40.80.70.71.60.40.40.4-0.40.9-0.20.2-0.30.1
Mg content in liver1.11.15.3-1.21.11.1-1.2-1.20.91.30.80.80.71.30.91.30.70.72.30.90.90.9-0.91.3-0.40.8-0.1-0.0
Mn content in liver1.21.35.21.2-1.3-1.31.41.4-0.90.20.00.30.40.90.31.01.11.11.11.01.01.0-1.00.4-1.31.42.3-2.1
Na content in liver1.11.15.4-0.90.80.8-1.1-1.10.6-0.3-0.3-0.7-0.2-0.4-0.3-0.8-1.4-1.4-1.0-0.7-0.7-0.70.7-1.50.0-1.3-2.32.3
Rb content in liver0.80.92.0-0.90.80.8-0.9-0.90.40.90.20.30.61.11.11.3-0.1-0.10.91.41.41.4-1.41.0-0.81.20.5-0.4
Se content in liver2.83.45.41.4-1.4-1.41.31.3-1.3-2.0-1.6-1.9-1.9-2.2-2.0-2.2-1.7-1.7-1.7-2.3-2.3-2.32.3-2.30.1-2.2-1.81.4
Sr content in liver0.20.20.50.7-0.6-0.60.60.6-0.6-0.6-0.3-0.3-0.1-0.3-0.6-0.5-0.10.0-0.6-0.3-0.3-0.30.3-0.6-0.3-0.20.1-0.3
Zn content in liver0.30.33.4-0.50.60.6-0.6-0.60.30.50.10.20.10.40.70.30.10.11.80.50.50.5-0.50.3-0.60.4-0.70.4
Bone: minimum diameter0.40.82.41.5-1.6-1.61.51.5-0.4-0.30.40.50.3-0.3-0.9-0.41.01.0-0.3-0.3-0.3-0.30.3-0.01.0-0.11.1-1.3
Time in familiar zone, hab. session 10.20.20.70.6-0.6-0.60.70.7-0.6-0.2-0.4-0.0-0.30.3-0.50.1-0.0-0.00.60.10.10.1-0.10.3-0.10.30.6-0.8
Time in novel zone, hab. session 10.20.20.6-0.50.60.6-0.8-0.80.70.50.40.30.5-0.00.40.30.40.40.20.50.50.5-0.50.20.20.1-0.10.4
Total zone transitions, hab. session 10.10.20.60.6-0.6-0.60.60.6-0.5-0.3-0.5-0.5-0.1-0.30.10.1-0.6-0.5-0.40.20.20.2-0.2-0.4-0.70.10.1-0.2
Total locomotion distance, hab. session 11.01.34.11.4-1.5-1.51.41.4-1.2-1.4-0.9-1.2-0.9-1.0-0.9-0.9-1.1-0.9-2.0-0.9-0.9-0.90.9-2.0-0.1-1.1-0.20.1
Locomotion velocity, hab. session 10.50.72.51.2-1.3-1.31.21.2-0.8-0.9-0.3-0.7-0.3-0.6-0.5-0.5-0.5-0.3-1.6-0.6-0.6-0.60.6-1.50.2-0.70.2-0.3
Time in familiar zone, hab. session 20.70.85.20.4-0.4-0.40.60.6-0.50.20.10.60.20.90.10.91.31.20.40.60.60.6-0.61.2-0.41.12.3-1.9
Time in novel zone, hab. session 20.30.32.5-0.30.30.3-0.6-0.60.40.10.0-0.3-0.1-0.40.2-0.3-0.7-0.70.4-0.1-0.1-0.10.1-0.40.3-0.6-1.61.3
Total zone transitions, hab. session 20.30.41.8-0.50.40.4-0.5-0.50.20.50.10.10.3-0.51.40.4-0.1-0.11.00.80.80.8-0.80.9-1.10.8-0.2-0.2
Total locomotion distance, hab. session 20.91.14.80.9-0.9-0.90.80.8-1.1-1.4-0.9-1.2-1.1-2.2-0.7-1.5-1.0-0.9-1.4-0.9-0.9-0.90.9-1.0-0.3-1.1-0.90.3
Locomotion velocity, hab. session 20.40.63.30.5-0.5-0.50.40.4-0.5-0.9-0.4-0.7-0.5-1.8-0.2-1.1-0.6-0.5-1.2-0.7-0.7-0.70.7-0.90.0-0.9-0.90.4
Novel to familiar place preference ratio0.10.10.6-0.10.10.1-0.1-0.10.40.00.2-0.0-0.0-0.4-0.0-0.30.10.20.1-0.6-0.6-0.60.6-0.20.3-0.5-0.80.6
Novelty place preference0.10.10.5-0.20.20.2-0.3-0.30.60.20.30.10.1-0.00.2-0.10.30.30.3-0.4-0.4-0.40.4-0.00.3-0.4-0.70.6
Time in novel zone, NPP test0.10.10.3-0.20.20.2-0.2-0.20.60.30.30.10.20.00.30.10.30.30.4-0.2-0.2-0.20.20.10.2-0.2-0.60.5
Total zone transitions, NPP test0.10.10.6-0.20.20.2-0.3-0.30.30.00.0-0.2-0.0-0.70.1-0.0-0.4-0.30.20.10.10.1-0.10.40.1-0.2-0.70.3
Total locomotion distance, NPP test0.30.41.60.4-0.3-0.30.20.2-0.2-0.6-0.2-0.5-0.4-1.3-0.6-0.8-0.6-0.5-1.1-0.5-0.5-0.50.5-0.80.3-0.9-0.70.5
Locomotion velocity, NPP test0.20.21.20.3-0.3-0.30.10.1-0.2-0.5-0.1-0.3-0.3-1.1-0.5-0.7-0.4-0.3-0.9-0.4-0.4-0.40.4-0.60.3-0.7-0.50.2
Intraocular pressure0.50.85.20.7-0.7-0.70.60.6-1.6-1.0-1.4-1.1-0.80.0-0.2-0.2-0.9-0.9-0.30.10.10.1-0.10.2-2.30.60.8-1.3
Delta distance traveled before/after self-admin0.20.21.20.3-0.4-0.40.40.40.10.30.80.70.60.2-0.60.20.30.4-0.20.50.50.5-0.5-0.31.10.30.7-0.4
Delta ambulatory time before/after self-admin0.10.21.10.4-0.3-0.30.30.30.10.20.70.60.5-0.1-0.40.00.40.4-0.40.30.30.3-0.3-0.41.10.20.6-0.4
Parametrial fat weight1.43.28.8-1.21.01.0-1.2-1.21.11.81.61.81.83.01.82.32.12.01.21.91.91.9-1.92.2-0.32.02.4-1.9
Pavlov. Cond. lever latency0.30.31.0-1.00.90.9-0.9-0.90.90.60.60.60.50.50.30.50.50.40.00.20.20.2-0.2-0.30.8-0.0-0.10.6
Pavlov. Cond. magazine entry latency0.20.20.8-0.60.70.7-0.7-0.70.50.20.10.00.2-0.50.6-0.1-0.5-0.60.30.30.30.3-0.30.50.10.1-0.90.6
Pavlov. Cond. change in total contacts0.10.10.30.10.10.10.00.0-0.2-0.0-0.1-0.20.0-0.40.50.1-0.4-0.40.40.40.40.4-0.40.5-0.60.4-0.2-0.2
Pavlov. Cond. index score0.10.20.80.3-0.1-0.10.20.2-0.5-0.4-0.5-0.6-0.4-0.60.0-0.4-0.8-0.90.00.20.20.2-0.20.3-0.80.0-0.4-0.0
Pavlov. Cond. latency score0.10.21.00.3-0.2-0.20.20.2-0.6-0.4-0.5-0.6-0.3-0.40.2-0.2-0.7-0.80.00.30.30.3-0.30.4-1.00.2-0.1-0.2
Pavlov. Cond. lever contacts0.20.20.90.7-0.5-0.50.50.5-0.8-0.5-0.5-0.5-0.4-0.4-0.1-0.3-0.5-0.50.10.10.10.1-0.10.5-0.90.20.1-0.6
Pavlov. Cond. magazine entry number0.20.30.60.4-0.5-0.50.60.6-0.3-0.3-0.00.0-0.30.2-0.8-0.20.60.7-0.2-0.8-0.8-0.80.8-0.60.6-0.50.5-0.2
Pavlov. Cond. intertrial magazine entries0.10.10.70.3-0.5-0.50.80.8-0.4-0.1-0.0-0.20.00.3-0.2-0.0-0.1-0.10.2-0.0-0.0-0.00.0-0.6-0.80.10.10.0
Pavlov. Cond. lever-magazine prob. diff.0.20.20.90.4-0.3-0.30.30.3-0.6-0.6-0.6-0.7-0.5-0.7-0.2-0.5-0.9-0.9-0.10.00.00.0-0.00.3-0.7-0.1-0.5-0.0
Pavlov. Cond. response bias0.10.10.80.3-0.2-0.20.10.1-0.1-0.3-0.2-0.3-0.1-0.80.1-0.5-0.6-0.7-0.0-0.0-0.0-0.00.00.1-0.2-0.2-0.90.3
Pavlov. Cond. lever latency3.24.37.3-2.12.12.1-2.1-2.12.72.62.62.62.52.42.02.42.52.41.81.81.81.8-1.81.51.81.20.6-0.1
Pavlov. Cond. magazine entry latency0.10.20.70.5-0.4-0.40.40.4-0.4-0.10.30.30.1-0.8-0.1-0.30.70.70.50.10.10.1-0.1-0.0-0.00.40.6-0.8
Pavlov. Cond. change in total contacts1.52.43.71.6-1.6-1.61.51.5-1.8-1.9-1.8-1.9-1.8-1.8-1.6-1.7-1.9-1.9-1.1-1.4-1.4-1.41.4-1.4-0.9-1.0-0.70.4
Pavlov. Cond. index score0.91.22.51.4-1.4-1.41.31.3-1.6-1.4-1.2-1.0-1.2-1.5-1.2-1.3-0.8-0.7-0.8-0.9-0.9-0.90.9-0.9-0.7-0.40.2-0.5
Pavlov. Cond. latency score0.70.92.31.3-1.2-1.21.11.1-1.5-1.3-1.1-1.0-1.0-1.3-0.9-1.0-0.7-0.7-0.7-0.7-0.7-0.70.7-0.7-1.0-0.20.4-0.6
Pavlov. Cond. lever contacts2.53.45.72.0-2.0-2.02.02.0-2.4-2.3-2.2-2.1-2.1-2.3-1.9-2.2-2.1-2.1-1.4-1.6-1.6-1.61.6-1.4-1.4-1.0-0.5-0.0
Pavlov. Cond. magazine entry number0.30.31.0-0.90.70.7-0.7-0.70.80.60.30.30.51.00.70.6-0.1-0.10.10.50.50.5-0.50.5-0.00.2-0.30.4
Pavlov. Cond. intertrial magazine entries0.91.32.60.9-1.1-1.11.11.1-0.5-1.1-0.6-0.6-1.0-1.6-1.4-1.5-0.4-0.5-1.4-1.6-1.6-1.61.6-0.90.9-1.4-0.80.7
Pavlov. Cond. lever-magazine prob. diff.0.81.12.31.5-1.4-1.41.41.4-1.5-1.3-0.9-0.9-1.0-1.4-1.2-1.1-0.6-0.5-0.7-0.8-0.8-0.80.8-0.8-0.6-0.30.4-0.6
Pavlov. Cond. response bias1.92.65.11.7-1.7-1.71.71.7-2.1-2.0-1.8-1.8-1.9-2.3-1.8-2.0-1.7-1.6-1.2-1.5-1.5-1.51.5-1.3-1.1-0.9-0.50.1
Time in closed arm before self-admin0.30.42.0-0.30.00.0-0.0-0.00.3-0.40.1-0.3-0.4-0.7-0.6-0.7-0.2-0.3-0.6-0.9-0.9-0.90.90.11.0-1.0-1.40.7
Time in closed arm after self-admin0.50.61.40.40.30.3-0.3-0.3-0.4-0.7-0.7-0.7-0.9-0.6-0.6-0.9-0.7-0.8-0.5-1.2-1.2-1.21.2-0.20.2-1.0-1.00.8
Time in open arm before self-admin0.50.64.60.50.10.1-0.1-0.1-0.9-0.1-1.0-0.5-0.20.21.00.2-0.6-0.51.10.70.70.7-0.70.6-2.11.10.5-0.7
Time in open arm after self-admin2.12.34.6-1.30.30.3-0.3-0.31.21.71.61.51.71.71.71.91.51.51.72.12.12.1-2.11.3-0.52.01.4-1.1
Bone: periosteal estimation0.40.83.01.7-1.7-1.71.71.7-0.7-0.6-0.1-0.10.1-0.1-0.8-0.60.30.4-0.6-0.6-0.6-0.60.6-0.30.7-0.30.5-1.0
Bone: periosteal perimeter0.61.03.41.7-1.7-1.71.91.9-0.7-0.7-0.1-0.2-0.1-0.1-1.0-0.7-0.10.0-0.8-0.8-0.8-0.80.8-0.80.9-0.60.2-0.7
Bone: post-yield work2.63.96.42.3-2.4-2.42.42.4-1.5-2.1-1.3-1.7-1.6-2.1-2.5-2.4-1.5-1.3-1.9-2.3-2.3-2.32.3-1.30.8-2.2-1.50.3
Progressive ratio test 1 active lever presses0.50.61.8-0.60.50.5-0.5-0.51.01.01.31.11.10.80.60.60.81.00.90.50.50.5-0.50.61.30.5-0.00.0
Progressive ratio test 1 breakpoint0.50.61.6-0.50.40.4-0.5-0.51.01.01.31.11.20.90.60.70.91.00.90.60.60.6-0.60.71.30.50.1-0.1
Progressive ratio test 1 inactive lever presses0.10.10.3-0.10.00.0-0.1-0.1-0.4-0.3-0.3-0.4-0.5-0.2-0.0-0.3-0.1-0.10.2-0.5-0.5-0.50.50.5-0.3-0.3-0.3-0.2
Progressive ratio test 2 active lever presses0.20.22.20.3-0.4-0.40.40.40.50.20.60.50.4-0.1-0.0-0.20.60.60.4-0.4-0.4-0.40.40.51.5-0.3-0.50.0
Progressive ratio test 2 breakpoint0.30.33.20.1-0.3-0.30.30.30.70.30.80.70.5-0.0-0.0-0.10.80.80.5-0.3-0.3-0.30.30.61.8-0.3-0.50.1
Progressive ratio test 2 inactive lever presses0.30.52.8-0.1-0.1-0.1-0.0-0.00.30.70.60.70.80.80.80.70.80.81.50.50.50.5-0.51.70.50.70.3-1.1
Incentive Sensitization - Responses0.40.62.30.3-0.3-0.30.40.40.3-0.40.1-0.1-0.3-1.3-0.3-1.10.40.3-0.2-1.2-1.2-1.21.20.21.5-1.0-1.20.4
Incentive Sensitization - Breakpoint0.50.62.20.3-0.4-0.40.50.50.2-0.50.0-0.1-0.3-1.3-0.4-1.10.40.3-0.2-1.2-1.2-1.21.20.21.5-1.0-1.10.4
Sum of active levers in priming session hrs 5-60.60.61.9-0.3-0.2-0.20.30.30.80.71.11.21.40.50.60.61.11.3-0.00.70.70.7-0.7-0.01.20.70.6-0.7
Progressive ratio0.10.20.70.2-0.8-0.80.80.80.1-0.10.10.1-0.1-0.2-0.5-0.3-0.1-0.1-0.10.00.00.0-0.00.80.7-0.4-0.3-0.2
Food seeking constrained by brief footshock0.50.62.9-0.1-0.0-0.0-0.1-0.1-0.6-0.7-1.2-0.9-0.8-0.8-0.3-0.8-1.6-1.7-0.9-0.3-0.3-0.30.3-0.7-0.7-0.6-1.21.0
Seeking ratio, punishment vs. effort0.20.31.5-0.21.21.2-1.2-1.2-0.20.0-0.30.00.1-0.30.4-0.1-0.3-0.4-0.1-0.0-0.0-0.00.0-1.1-0.30.3-0.10.6
Retroperitoneal fat weight1.46.011.0-3.23.13.1-3.3-3.33.22.93.02.63.33.12.52.61.71.80.32.12.12.1-2.10.91.91.30.60.6
Reaction time number correct1.01.93.7-1.91.81.8-1.9-1.91.81.71.71.51.70.71.61.00.91.01.61.11.11.1-1.10.90.71.0-0.40.7
Reaction time mean minus median0.10.31.40.00.40.4-0.4-0.40.10.30.40.70.00.2-0.30.51.21.10.30.20.20.2-0.20.40.40.11.1-0.7
Reaction time mean minus median AUC0.20.42.0-0.10.50.5-0.4-0.40.60.40.80.80.20.2-0.60.31.41.30.1-0.3-0.3-0.30.3-0.11.4-0.50.5-0.1
Reaction time num false alarms0.50.71.6-0.90.80.8-0.9-0.90.10.50.20.30.81.31.11.00.00.1-0.11.21.21.2-1.20.7-1.11.10.8-0.6
Reaction time num false alarms AUC0.40.61.4-0.90.80.8-0.8-0.80.10.50.30.30.61.21.10.90.20.20.11.01.01.0-1.00.9-0.90.90.7-0.7
Reaction time trials correct on left1.01.93.7-1.91.81.8-1.9-1.91.81.71.71.51.70.71.61.00.91.01.61.11.11.1-1.10.90.71.0-0.40.7
Reaction time trials on left1.12.03.8-1.91.81.8-1.9-1.91.91.71.81.61.80.81.61.10.91.11.61.11.11.1-1.10.90.71.1-0.40.7
Reaction time mean0.50.83.8-0.30.40.4-0.2-0.21.20.91.41.40.90.30.30.51.92.00.40.20.20.2-0.20.71.80.20.8-0.6
Reaction time mean AUC0.81.24.9-0.60.80.8-0.6-0.61.41.21.61.71.20.50.70.82.12.20.70.40.40.4-0.41.11.80.50.9-0.7
Median of all reaction times0.60.93.6-0.50.40.4-0.2-0.21.31.01.51.51.10.30.50.51.81.90.40.20.20.2-0.20.81.90.30.5-0.4
Reaction time omissions1.62.34.4-1.92.02.0-2.1-2.11.81.71.41.51.41.62.11.71.81.71.11.01.01.0-1.01.50.21.00.50.0
Reaction time false alarm rate0.20.21.20.1-0.1-0.10.20.2-0.7-0.4-0.6-0.4-0.20.70.20.3-0.3-0.3-0.70.40.40.4-0.40.3-1.10.30.8-0.9
Reaction time premature initiation rate0.60.92.50.5-0.8-0.80.80.8-0.5-0.9-0.7-1.0-0.8-0.8-0.9-1.0-1.3-1.2-1.3-0.9-0.9-0.90.9-1.6-0.4-0.8-0.71.1
Reaction time premature initiations0.10.21.9-0.70.30.3-0.3-0.30.70.30.50.10.4-0.20.2-0.3-0.4-0.4-0.3-0.1-0.1-0.10.1-0.90.3-0.2-0.91.4
Std. dev. reaction times0.61.14.2-0.71.01.0-0.9-0.91.21.11.41.51.00.80.60.92.02.10.50.40.40.4-0.40.71.30.41.1-0.5
Reaction time trials completed1.12.03.8-1.91.81.8-1.9-1.91.91.71.81.61.80.81.61.10.91.11.61.11.11.1-1.10.90.71.1-0.40.7
Reaction time trials AUC0.91.83.3-1.81.71.7-1.8-1.81.81.61.71.51.70.71.51.00.91.01.51.11.11.1-1.10.80.71.1-0.30.7
Run reversals in cocaine runway, females2.22.25.2-1.81.91.9-1.7-1.72.01.62.12.11.50.30.90.82.22.31.10.70.70.7-0.71.02.10.60.1-0.3
Run reversals in cocaine runway, males0.30.31.2-0.80.70.7-0.6-0.60.50.60.20.10.60.71.10.7-0.1-0.20.50.50.50.5-0.50.3-0.60.4-0.60.5
Latency to leave start box in cocaine runway7.58.614.3-3.72.82.8-2.8-2.83.63.73.53.73.82.93.63.03.33.32.42.82.82.8-2.81.61.52.61.4-0.4
Latency to leave start box in cocaine runway, F2.22.66.5-2.11.41.4-1.5-1.52.32.22.32.12.61.62.11.61.41.50.81.31.31.3-1.30.61.51.10.10.3
Latency to leave start box in cocaine runway, M5.24.87.2-2.52.12.1-2.1-2.12.02.52.02.52.22.12.52.32.72.52.22.42.42.4-2.41.5-0.12.52.1-1.1
Std. dev. time between licks in bursts2.12.95.32.1-1.8-1.81.81.8-2.2-2.3-1.9-2.0-2.1-1.7-2.0-1.8-1.0-1.1-1.9-1.7-1.7-1.71.7-0.8-0.9-1.40.2-1.0
Total sessions with >9 infusions0.30.31.50.8-1.2-1.21.11.10.00.20.30.20.40.4-0.30.10.20.00.60.10.10.1-0.10.10.90.1-0.2-0.3
Short access day 1 total inactive lever presses0.40.61.70.4-1.1-1.11.11.1-0.40.1-0.10.10.30.9-0.00.70.1-0.00.60.90.90.9-0.90.9-0.60.80.8-1.3
Short access day 10 total inactive lever presses0.30.82.40.8-1.0-1.01.01.0-1.5-1.0-1.1-0.9-1.10.1-1.0-0.2-0.7-0.6-0.5-0.3-0.3-0.30.30.3-1.40.01.2-1.5
Short access day 1 total infusions0.20.31.30.8-1.1-1.11.21.2-0.0-0.00.10.10.50.2-0.5-0.1-0.1-0.30.00.10.10.1-0.10.01.0-0.1-0.4-0.1
Short access day 10 total infusions0.50.71.9-0.60.30.3-0.2-0.21.11.11.41.11.31.30.21.10.60.50.50.80.80.8-0.80.61.40.40.00.1
Short access total infusions0.50.71.7-0.20.00.00.10.11.01.11.31.01.31.20.40.90.80.71.00.90.90.9-0.90.71.20.60.1-0.1
Short access day 1 locomotion0.20.30.80.8-0.7-0.70.80.80.10.30.40.50.60.5-0.30.30.60.40.20.30.30.3-0.30.40.90.20.6-0.8
Short access day 10 total locomotion0.61.22.9-0.90.70.7-0.7-0.71.11.41.41.41.31.70.31.50.91.11.21.21.21.2-1.20.91.20.70.7-0.6
Short access total locomotion0.30.31.30.2-0.3-0.30.20.20.40.60.90.80.81.1-0.30.70.50.50.50.50.50.5-0.50.31.10.30.6-0.6
One hour access (0.3 mA shock)0.10.10.30.2-0.2-0.2-0.0-0.0-0.2-0.3-0.3-0.3-0.4-0.0-0.5-0.2-0.1-0.20.1-0.5-0.5-0.50.50.40.3-0.5-0.30.2
Compulsive drug intake2.63.15.41.6-1.6-1.61.41.4-1.3-2.0-1.6-1.8-1.8-2.3-2.1-2.2-1.3-1.4-2.3-1.9-1.9-1.91.9-2.30.1-1.9-1.21.1
One hour access (shock baseline)0.71.12.9-0.90.80.8-0.8-0.80.61.20.90.90.91.71.01.50.50.61.61.11.11.1-1.11.7-0.11.10.7-0.6
Social response proportion0.20.20.5-0.10.50.5-0.7-0.7-0.3-0.3-0.5-0.4-0.60.4-0.10.3-0.3-0.30.3-0.4-0.4-0.40.40.7-0.2-0.3-0.20.1
Social responses0.70.92.11.5-1.4-1.41.21.2-1.2-1.2-1.1-0.8-1.3-0.6-1.1-0.8-0.4-0.4-0.4-1.0-1.0-1.01.0-0.2-0.1-0.70.4-0.7
Social time0.20.32.10.3-0.2-0.20.40.40.30.20.30.2-0.20.30.00.30.90.91.00.20.20.2-0.21.50.60.00.4-0.8
Soleus weight0.82.44.21.3-1.2-1.21.21.2-1.7-1.9-1.9-2.1-1.7-1.1-1.4-1.6-2.0-1.9-1.5-1.8-1.8-1.81.8-1.5-0.8-1.5-1.00.7
Bone: stiffness0.91.54.70.5-0.5-0.50.40.40.20.81.00.91.11.90.61.51.51.60.81.31.31.3-1.31.5-0.41.32.2-2.0
Tibialis anterior weight4.214.327.85.2-5.3-5.35.25.2-3.8-4.2-3.4-3.4-3.8-3.5-4.4-4.0-2.8-2.6-2.6-3.9-3.9-3.93.9-2.40.8-3.4-1.40.0
Time to tail flick, vehicle, before self-admin0.30.31.60.4-1.0-1.01.31.3-0.3-0.2-0.2-0.30.20.20.20.0-0.5-0.2-0.30.10.10.1-0.10.1-0.80.20.1-0.4
Time to tail flick, vehicle, after self-admin0.50.62.0-0.40.50.5-0.7-0.70.40.70.61.00.30.6-0.00.81.11.01.20.70.70.7-0.71.40.20.71.2-1.2
Time to tail flick, test, before self-admin0.70.71.30.5-0.5-0.50.60.6-0.7-1.1-1.0-0.9-0.9-1.1-0.9-1.0-0.5-0.4-1.2-1.1-1.1-1.11.1-0.80.1-1.1-0.50.2
Time to tail flick, test, after self-admin0.40.43.00.10.10.1-0.0-0.00.80.41.11.01.00.3-0.10.20.91.0-1.00.10.10.1-0.1-0.61.7-0.10.70.1
Delta time to tail flick, vehicle, before/after SA1.00.93.0-1.01.41.4-1.7-1.71.30.91.01.10.40.30.00.51.41.20.70.40.40.4-0.40.91.30.00.20.1
Delta time to tail flick, test, before/after SA1.21.24.6-0.60.60.6-0.5-0.51.61.32.01.81.81.00.50.91.51.4-0.10.90.90.9-0.9-0.12.10.50.70.3
Tibia length0.10.31.00.8-0.9-0.90.70.7-0.7-0.2-0.3-0.30.20.90.20.50.10.1-0.1-0.2-0.2-0.20.20.2-0.80.31.0-1.0
Ambulatory time before self-admin0.30.51.80.00.20.2-0.2-0.2-0.3-0.6-0.8-0.8-0.5-0.2-0.1-0.6-1.0-1.1-1.0-0.6-0.6-0.60.6-1.0-0.6-0.7-0.81.3
Ambulatory time after self-admin0.10.10.30.20.20.2-0.1-0.1-0.30.10.20.10.40.50.20.2-0.2-0.3-0.30.50.50.5-0.5-0.5-0.40.50.5-0.0
Bone: tissue strength3.94.012.71.8-1.7-1.71.81.8-3.0-2.5-3.1-3.1-2.5-1.0-1.2-1.4-2.6-2.5-1.9-1.4-1.4-1.41.4-0.4-3.6-0.60.2-1.0
Total heroin consumption3.23.75.8-1.11.21.2-1.1-1.11.42.11.92.02.32.42.12.42.12.41.62.42.42.4-2.41.3-0.42.32.4-1.7
Bone: trabecular number1.72.84.21.8-1.8-1.82.12.1-1.5-1.9-1.7-1.7-1.8-1.8-1.6-2.0-1.8-1.7-1.1-1.7-1.7-1.71.7-1.10.2-1.7-1.50.6
Bone: trabecular spacing3.14.16.6-2.12.12.1-2.1-2.11.62.21.81.92.11.92.52.41.91.91.72.22.22.2-2.22.6-0.72.41.7-1.3
Bone: trabecular thickness2.43.06.12.4-2.4-2.42.52.5-2.0-1.8-1.7-1.6-1.7-1.2-1.7-1.9-1.4-1.4-0.6-1.7-1.7-1.71.7-1.30.0-1.4-0.8-0.2
Bone: trabecular tissue density0.30.41.9-0.60.50.5-0.6-0.6-0.10.50.10.20.61.40.81.00.10.10.30.70.70.7-0.7-0.9-0.90.90.90.2
Water consumed over 24 hours0.20.31.90.2-0.2-0.20.20.2-0.10.30.40.50.50.50.50.30.80.80.40.30.30.3-0.31.00.10.60.9-1.4
Number of responses in last shaping day1.82.04.7-0.20.10.1-0.0-0.01.41.61.61.91.81.71.01.72.22.12.01.41.41.4-1.41.61.41.31.1-1.4