Hub : Traits : Tibialis anterior weight : ← : →

chr15:35,841,493-43,041,493

Trait: Tibialis anterior weight

Best TWAS P=5.58e-09 · Best GWAS P=5.35e-09 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Bnip3l	alternative TSS	XM_039092965.1	0.08	1	0.06	1.8e-07	-5.35	8.70e-08	0.59	FALSE
Adipose	Bnip3l	alternative TSS	XM_006252091.3	0.02	1	0.02	1.3e-03	5.35	8.70e-08	0.04	FALSE
Adipose	Bnip3l	alternative TSS	XM_039092965.1	0.06	1	0.05	5.6e-06	-5.35	8.70e-08	0.43	FALSE
Adipose	Fam124a	gene expression	Fam124a	0.03	2137	0.01	5.9e-02	5.55	2.82e-08	0.44	TRUE
Adipose	Fzd3	gene expression	Fzd3	0.03	1	0.03	5.3e-04	5.34	9.17e-08	0.1	FALSE
Adipose	Gulo	gene expression	Gulo	0.24	1909	0.23	2.8e-25	5.27	1.36e-07	0.58	FALSE
Adipose	Ints9	gene expression	Ints9	0.1	1361	0.06	1.4e-07	-5.19	2.05e-07	0.63	FALSE
Adipose	Kif13b	gene expression	Kif13b	0.08	1	0.09	7.8e-10	5.34	9.39e-08	0.63	FALSE
Adipose	LOC120097019	gene expression	LOC120097019	0.03	1558	0.02	4.5e-03	-5.25	1.52e-07	0.65	FALSE
Adipose	LOC120097103	gene expression	LOC120097103	0.03	1	0.02	2.5e-03	5.32	1.01e-07	0.05	FALSE
Adipose	Ppp2r2a	gene expression	Ppp2r2a	0.07	1	0.05	3.7e-06	5.35	8.70e-08	0.56	FALSE
Adipose	Sox7	gene expression	Sox7	0.14	1399	0.09	3.4e-10	5.65	1.56e-08	0.78	FALSE
Adipose	Bnip3l	isoform ratio	XM_039092965.1	0.1	1	0.08	3.1e-09	-5.38	7.37e-08	0.64	FALSE
Adipose	Dock5	mRNA stability	Dock5	0.12	470	0.1	1.8e-11	-5.36	8.39e-08	0.68	FALSE
Adipose	Ints6	mRNA stability	Ints6	0.02	1842	0.01	9.8e-03	-5.36	8.38e-08	0.36	FALSE
Adipose	Ptk2b	mRNA stability	Ptk2b	0.03	1	0.02	2.7e-03	5.35	8.64e-08	0.06	FALSE
BLA	Msra	alternative TSS	XM_039093217.1	0.1	1	0.06	2.3e-04	-5.27	1.37e-07	0.07	FALSE
BLA	Prss55	alternative TSS	XM_039093917.1	0.24	37	0.04	3.9e-03	-5.25	1.49e-07	0.55	FALSE
BLA	Fbxo16	gene expression	Fbxo16	0.26	31	0.16	6.3e-09	-5.18	2.19e-07	0.71	FALSE
BLA	Gucy1b2	gene expression	Gucy1b2	0.31	35	0.29	1.2e-15	-5.4	6.81e-08	0.47	FALSE
BLA	Kctd9	gene expression	Kctd9	0.1	1	0.07	1.1e-04	-5.29	1.22e-07	0.14	FALSE
BLA	LOC102554746	gene expression	LOC102554746	0.15	1	0.13	2.2e-07	5.52	3.36e-08	0.53	FALSE
BLA	Nefm	gene expression	Nefm	0.14	488	0.06	2.4e-04	5.35	9.03e-08	0.64	FALSE
BLA	Pinx1	gene expression	Pinx1	0.06	9	0.03	7.9e-03	-5.57	2.51e-08	0.7	FALSE
BLA	Prss55	gene expression	Prss55	0.54	72	0.47	1.4e-27	-5.44	5.35e-08	0.73	FALSE
BLA	Stmn4	gene expression	Stmn4	0.08	1	0.05	1.2e-03	-5.26	1.46e-07	0.05	FALSE
BLA	Wdfy2	gene expression	Wdfy2	0.11	1789	0.04	5.9e-03	5.65	1.65e-08	0.23	FALSE
BLA	Ints6	isoform ratio	NM_001271488.1	0.06	1843	0.02	1.8e-02	-5.59	2.27e-08	0.38	FALSE
BLA	Ints6	isoform ratio	XM_039093512.1	0.08	1843	0.02	3.2e-02	5.22	1.77e-07	0.43	FALSE
BLA	Prss55	isoform ratio	XM_039093916.1	0.1	1	0.06	6.6e-04	-5.68	1.38e-08	0.24	FALSE
BLA	Prss55	isoform ratio	XM_039093917.1	0.1	19	0.05	1.3e-03	-5.53	3.26e-08	0.68	FALSE
BLA	Prss55	intron excision ratio	chr15_38340170_38344928	0.07	1	0.03	1.4e-02	5.27	1.37e-07	0.06	FALSE
BLA	Ptk2b	intron excision ratio	chr15_40414856_40481059	0.3	7	0.15	2.3e-08	-5.47	4.48e-08	0.71	TRUE
BLA	Rnaseh2b	intron excision ratio	chr15_36576723_36583517	0.07	1	0.06	2.2e-04	-5.69	1.27e-08	0.1	FALSE
BLA	Dock5	mRNA stability	Dock5	0.07	1	0.01	5.7e-02	5.29	1.22e-07	0.04	FALSE
BLA	Fam124a	mRNA stability	Fam124a	0.1	1	0.08	3.7e-05	5.41	6.31e-08	0.09	FALSE
Brain	Bnip3l	alternative polyA	NM_080888.2	0.03	1465	0.03	1.2e-03	5.36	8.25e-08	0.56	FALSE
Brain	Bnip3l	alternative polyA	XM_039092964.1	0.03	1	0.03	7.9e-04	5.43	5.66e-08	0.05	FALSE
Brain	Dock5	alternative polyA	XM_039093338.1	0.04	473	0.03	5.3e-04	5.35	8.86e-08	0.63	FALSE
Brain	Dock5	alternative polyA	XM_039093339.1	0.03	473	0.03	7.1e-04	-5.35	8.75e-08	0.62	FALSE
Brain	Prss55	alternative TSS	XM_039093917.1	0.04	1	0.05	3.0e-05	5.69	1.28e-08	0.57	FALSE
Brain	Prss55	alternative TSS	XM_039093918.1	0.12	1	0.03	1.3e-03	-5.36	8.29e-08	0.34	FALSE
Brain	Prss55	alternative TSS	XM_039093917.1	0.08	1	0.06	1.9e-06	5.36	8.29e-08	0.62	FALSE
Brain	Prss55	alternative TSS	XM_039093918.1	0.24	1	0.04	6.5e-05	-5.36	8.29e-08	0.57	FALSE
Brain	Dock5	gene expression	Dock5	0.25	473	0.26	1.4e-24	-5.36	8.51e-08	0.67	FALSE
Brain	Gucy1b2	gene expression	Gucy1b2	0.23	7	0.24	1.6e-22	-5.43	5.63e-08	0.43	FALSE
Brain	Ints6	gene expression	Ints6	0.06	1843	0.05	1.1e-05	-5.65	1.61e-08	0.55	FALSE
Brain	Kctd9	gene expression	Kctd9	0.11	52	0.11	1.1e-10	-5.29	1.21e-07	0.74	FALSE
Brain	LOC120097103	gene expression	LOC120097103	0.09	1	0.13	8.7e-12	5.21	1.91e-07	0.5	FALSE
Brain	Nefm	gene expression	Nefm	0.19	1	0.19	1.6e-17	-5.3	1.18e-07	0.65	FALSE
Brain	Pinx1	gene expression	Pinx1	0.11	1426	0.05	2.1e-05	5.3	1.17e-07	0.72	FALSE
Brain	Prss52	gene expression	Prss52	0.14	1	0.16	8.1e-15	5.37	7.76e-08	0.71	FALSE
Brain	Prss55	gene expression	Prss55	0.38	1	0.4	2.1e-39	5.23	1.68e-07	0.54	FALSE
Brain	Stmn4	gene expression	Stmn4	0.21	62	0.23	2.2e-21	-5.26	1.42e-07	0.37	FALSE
Brain	Adra1a	isoform ratio	XM_039093212.1	0.06	2027	0.04	3.4e-04	5.33	9.90e-08	0.52	TRUE
Brain	Dock5	isoform ratio	XM_039093339.1	0.04	1	0.03	7.5e-04	5.33	9.68e-08	0.06	FALSE
Brain	Prss55	isoform ratio	XM_039093917.1	0.05	1	0.03	1.1e-03	5.36	8.29e-08	0.07	FALSE
Brain	Prss55	isoform ratio	XM_039093918.1	0.11	1	0.03	6.7e-04	-5.36	8.29e-08	0.38	FALSE
Brain	Stmn4	isoform ratio	NM_001270856.1	0.07	2138	0.06	5.8e-06	5.37	8.08e-08	0.49	FALSE
Brain	Prss55	intron excision ratio	chr15_38340170_38344928	0.07	26	0.06	1.6e-06	5.62	1.86e-08	0.74	FALSE
Brain	Ptk2b	intron excision ratio	chr15_40414856_40481059	0.16	2108	0.16	5.7e-15	-5.32	1.05e-07	0.45	FALSE
Brain	Stmn4	intron excision ratio	chr15_40553358_40554341	0.31	19	0.17	8.5e-16	5.19	2.15e-07	0.43	FALSE
Brain	Stmn4	intron excision ratio	chr15_40554019_40554341	0.12	4	0.12	7.0e-11	-5.35	8.73e-08	0.58	FALSE
Brain	Dock5	mRNA stability	Dock5	0.06	473	0.05	1.4e-05	-5.35	8.84e-08	0.68	FALSE
Brain	Extl3	mRNA stability	Extl3	0.04	1385	0.02	2.4e-03	-5.55	2.92e-08	0.6	FALSE
IL	Gucy1b2	gene expression	Gucy1b2	0.24	1	0.09	4.3e-03	5.45	5.16e-08	0.05	FALSE
IL	Nefl	mRNA stability	Nefl	0.18	1	0.04	4.3e-02	-5.29	1.22e-07	0.06	FALSE
LHb	Bnip3l	gene expression	Bnip3l	0.29	1465	0.14	4.0e-04	-5.34	9.16e-08	0.53	FALSE
LHb	Dock5	gene expression	Dock5	0.41	473	0.21	1.2e-05	-5.35	8.80e-08	0.66	FALSE
LHb	Gucy1b2	gene expression	Gucy1b2	0.24	2144	0.11	1.8e-03	-5.18	2.19e-07	0.24	FALSE
LHb	Kctd9	gene expression	Kctd9	0.22	13	0.07	9.6e-03	-5.25	1.54e-07	0.46	FALSE
LHb	LOC108352941	gene expression	LOC108352941	0.29	1	0.15	2.0e-04	5.24	1.64e-07	0.1	FALSE
LHb	Scara5	mRNA stability	Scara5	0.19	1	0.04	3.9e-02	-5.24	1.64e-07	0.05	TRUE
Liver	Chrna2	gene expression	Chrna2	0.06	2038	0.06	6.1e-07	-5.21	1.89e-07	0.55	FALSE
Liver	Dock5	gene expression	Dock5	0.12	1	0.1	2.5e-11	5.33	9.68e-08	0.69	FALSE
Liver	Extl3	gene expression	Extl3	0.05	1	0.07	3.3e-08	5.3	1.18e-07	0.62	FALSE
Liver	Prss52	gene expression	Prss52	0.04	1	0.02	1.2e-03	5.83	5.58e-09	0.68	TRUE
Liver	Wdfy2	gene expression	Wdfy2	0.47	1788	0.41	4.9e-49	-5.38	7.41e-08	0.14	FALSE
Liver	Zfp395	gene expression	Zfp395	0.02	1	0.02	5.1e-03	-5.24	1.60e-07	0.04	FALSE
Liver	Msra	isoform ratio	XM_039093216.1	0.04	1	0.02	1.2e-03	-5.37	7.76e-08	0.16	FALSE
Liver	Rnaseh2b	intron excision ratio	chr15_36576723_36581882	0.06	1	0.06	1.3e-07	5.52	3.36e-08	0.55	FALSE
Liver	Dock5	mRNA stability	Dock5	0.02	1	0.02	4.6e-03	5.33	9.68e-08	0.03	FALSE
Liver	Gucy1b2	mRNA stability	Gucy1b2	0.15	2141	0.2	1.9e-21	-5.27	1.36e-07	0.4	FALSE
NAcc	Defb41	gene expression	Defb41	0.02	10	0.03	1.4e-04	-5.6	2.11e-08	0.52	FALSE
NAcc	Dock5	gene expression	Dock5	0.08	473	0.07	2.5e-08	-5.35	8.78e-08	0.68	FALSE
NAcc	Extl3	gene expression	Extl3	0.05	1	0.06	5.4e-07	-5.34	9.17e-08	0.68	FALSE
NAcc	Fbxo16	gene expression	Fbxo16	0.24	136	0.24	6.7e-27	5.17	2.28e-07	0.71	FALSE
NAcc	Gucy1b2	gene expression	Gucy1b2	0.23	1	0.25	2.3e-28	5.64	1.65e-08	0.7	FALSE
NAcc	Ints6	gene expression	Ints6	0.09	1	0.06	1.6e-07	5.36	8.43e-08	0.3	FALSE
NAcc	Kctd9	gene expression	Kctd9	0.19	327	0.12	5.0e-14	5.27	1.33e-07	0.78	FALSE
NAcc	LOC102554746	gene expression	LOC102554746	0.06	2080	0.08	3.9e-09	-5.34	9.20e-08	0.48	FALSE
NAcc	LOC120097103	gene expression	LOC120097103	0.03	1	0	1.2e-01	5.29	1.25e-07	0.05	FALSE
NAcc	Nefm	gene expression	Nefm	0.1	488	0.08	6.9e-10	5.34	9.10e-08	0.68	FALSE
NAcc	Prss55	gene expression	Prss55	0.35	1481	0.27	1.5e-31	-5.18	2.22e-07	0.7	FALSE
NAcc	Extl3	isoform ratio	XM_039093622.1	0.03	1	0.01	2.6e-02	5.34	9.17e-08	0.04	TRUE
NAcc	Stmn4	isoform ratio	XM_008770778.2	0.03	1	0.01	7.3e-03	5.29	1.22e-07	0.09	FALSE
NAcc	Stmn4	isoform ratio	XM_039093677.1	0.42	12	0.27	2.0e-31	-5.3	1.17e-07	0	TRUE
NAcc	Adra1a	intron excision ratio	chr15_40922033_40922127	0.03	2027	0.01	1.3e-02	5.41	6.31e-08	0.46	FALSE
NAcc	Gucy1b2	intron excision ratio	chr15_36640915_36643646	0.1	2144	0.04	4.9e-05	-5.58	2.38e-08	0.58	FALSE
NAcc	Gucy1b2	intron excision ratio	chr15_36642868_36643646	0.09	2144	0.03	7.8e-05	5.57	2.59e-08	0.58	FALSE
NAcc	LOC102554489	intron excision ratio	chr15_38820277_38825743	0.04	1	0.02	9.0e-04	-5.32	1.01e-07	0.1	FALSE
NAcc	Ppp2r2a	intron excision ratio	chr15_41261896_41263615	0.06	1310	0.04	6.2e-06	5.33	9.75e-08	0.68	FALSE
NAcc	Stmn4	intron excision ratio	chr15_40553358_40553939	0.25	6	0.12	6.0e-14	-5.3	1.18e-07	0.48	FALSE
NAcc	Stmn4	intron excision ratio	chr15_40553358_40554341	0.24	1	0.1	4.2e-12	-5.18	2.17e-07	0.44	FALSE
NAcc	Dock5	mRNA stability	Dock5	0.05	473	0.03	1.4e-04	-5.36	8.49e-08	0.68	FALSE
NAcc	Ppp2r2a	mRNA stability	Ppp2r2a	0.05	17	0.03	4.1e-04	5.36	8.31e-08	0.67	FALSE
OFC	Bnip3l	gene expression	Bnip3l	0.2	25	0.04	3.3e-02	-5.44	5.46e-08	0.27	FALSE
PL	Prss55	alternative TSS	XM_039093917.1	0.03	1481	0.02	2.0e-03	-5.31	1.08e-07	0.66	FALSE
PL	Prss55	alternative TSS	XM_039093918.1	0.03	1	0.03	1.9e-04	-5.18	2.20e-07	0.05	FALSE
PL	Prss55	alternative TSS	XM_039093917.1	0.04	1481	0.03	2.8e-04	-5.21	1.84e-07	0.66	FALSE
PL	Prss55	alternative TSS	XM_039093918.1	0.05	1	0.05	1.3e-06	-5.18	2.20e-07	0.36	FALSE
PL	Bnip3l	gene expression	Bnip3l	0.07	38	0.04	1.1e-05	5.2	1.98e-07	0.63	FALSE
PL	Fam124a	gene expression	Fam124a	0.04	1	0.03	5.6e-04	-5.48	4.16e-08	0.06	FALSE
PL	Fbxo16	gene expression	Fbxo16	0.25	1	0.28	8.1e-31	5.21	1.91e-07	0.57	FALSE
PL	Gucy1b2	gene expression	Gucy1b2	0.42	48	0.4	2.1e-47	-5.37	7.89e-08	0.48	FALSE
PL	Kctd9	gene expression	Kctd9	0.12	1	0.12	3.4e-13	-5.34	9.19e-08	0.78	FALSE
PL	LOC120097017	gene expression	LOC120097017	0.03	1398	0.01	1.1e-02	5.41	6.33e-08	0.6	FALSE
PL	Nefl	gene expression	Nefl	0.04	482	0.02	4.2e-03	-5.36	8.52e-08	0.62	FALSE
PL	Nefm	gene expression	Nefm	0.05	1	0.04	4.2e-05	-5.34	9.37e-08	0.28	FALSE
PL	Prss55	gene expression	Prss55	0.22	1	0.21	1.7e-22	5.69	1.28e-08	0.93	FALSE
PL	Wdfy2	gene expression	Wdfy2	0.02	1	0.02	9.2e-04	-5.51	3.52e-08	0.06	FALSE
PL	Prss55	isoform ratio	XM_039093918.1	0.03	1	0.03	3.3e-04	-5.18	2.20e-07	0.04	FALSE
PL	Adra1a	intron excision ratio	chr15_40922349_40926019	0.02	1	0.01	3.5e-02	5.39	6.90e-08	0.04	FALSE
PL	Ptk2b	intron excision ratio	chr15_40414856_40481059	0.53	71	0.26	6.3e-28	5.28	1.31e-07	0.49	FALSE
pVTA	Prss55	alternative TSS	XM_039093917.1	0.16	1	0.14	1.1e-06	5.35	8.88e-08	0.65	FALSE
pVTA	Prss55	alternative TSS	XM_039093917.1	0.15	1	0.14	1.0e-06	5.35	8.88e-08	0.61	FALSE
pVTA	Dock5	gene expression	Dock5	0.37	473	0.26	1.4e-11	-5.34	9.46e-08	0.68	FALSE
pVTA	Extl3	gene expression	Extl3	0.12	1	0.13	3.7e-06	-5.42	5.81e-08	0.48	FALSE
pVTA	Fbxo16	gene expression	Fbxo16	0.1	1428	0.04	5.4e-03	-5.57	2.58e-08	0.66	FALSE
pVTA	Kctd9	gene expression	Kctd9	0.09	327	0.08	2.2e-04	5.38	7.51e-08	0.74	FALSE
pVTA	LOC102554746	gene expression	LOC102554746	0.26	1	0.23	2.4e-10	5.65	1.60e-08	0.71	FALSE
pVTA	LOC120097012	gene expression	LOC120097012	0.09	1	0.09	1.4e-04	-5.34	9.25e-08	0.15	FALSE
pVTA	Wdfy2	gene expression	Wdfy2	0.09	1789	0.05	2.4e-03	5.52	3.37e-08	0.32	FALSE
pVTA	Rnaseh2b	intron excision ratio	chr15_36495129_36498293	0.11	1	0.09	1.3e-04	5.65	1.60e-08	0.13	FALSE
pVTA	Fam124a	mRNA stability	Fam124a	0.1	2140	0.04	1.1e-02	-5.19	2.10e-07	0.37	FALSE