chr12:27,006-4,653,252

Trait: Tibialis anterior weight

Best TWAS P=3.96e-10 · Best GWAS P=2.41e-08 conditioned to 1.00e+00

Associated models

Tissue Gene RNA modality RNA phenotype h2 # weights Model R2 Model R2 P TWAS Z TWAS P Coloc P Joint
Adipose N4bp2l2 alternative polyA ENSRNOT00000111844 0.14 1 0.12 7.1e-13 5.29 1.21e-07 0.92 FALSE
Adipose N4bp2l2 alternative polyA ENSRNOT00000118063 0.14 1 0.12 3.9e-13 -5.29 1.21e-07 0.92 FALSE
Adipose Pet100 alternative TSS ENSRNOT00000071928 0.22 116 0.13 3.4e-14 5.58 2.45e-08 0.79 FALSE
Adipose Pet100 alternative TSS ENSRNOT00000107172 0.22 122 0.13 2.6e-14 -5.59 2.24e-08 0.79 FALSE
Adipose Trappc5 gene expression ENSRNOG00000001003 0.09 1 0.03 9.9e-05 -5.38 7.44e-08 0.26 FALSE
Adipose Evi5l gene expression ENSRNOG00000001034 0.09 1 -0 4.2e-01 5.45 5.12e-08 0.04 FALSE
Adipose Mcemp1 gene expression ENSRNOG00000028259 0.15 1 0.06 3.2e-07 5.3 1.15e-07 0.73 FALSE
Adipose Insr gene expression ENSRNOG00000029986 0.13 1 0.02 4.3e-03 5.16 2.52e-07 0.03 FALSE
Adipose N4bp2l1 gene expression ENSRNOG00000059322 0.32 16 0.24 1.2e-26 -5.46 4.89e-08 0.93 FALSE
Adipose Pet100 isoform ratio ENSRNOT00000071928 0.23 64 0.13 1.8e-14 5.63 1.81e-08 0.82 FALSE
Adipose Pet100 isoform ratio ENSRNOT00000107172 0.23 66 0.13 2.6e-14 -5.63 1.76e-08 0.82 FALSE
Adipose Zfp958 isoform ratio ENSRNOT00000102786 0.03 169 0.01 6.9e-03 5.43 5.72e-08 0.3 FALSE
Adipose Zfp958 intron excision ratio chr12:3971128:3971331 0.03 1113 0.01 2.8e-02 5.56 2.67e-08 0.19 FALSE
Adipose Elavl1 mRNA stability ENSRNOG00000001069 0.16 2406 0.07 9.4e-09 5.65 1.60e-08 0.24 FALSE
Adipose Cers4 mRNA stability ENSRNOG00000001072 0.14 1 0.09 1.7e-10 5.09 3.49e-07 0.6 FALSE
BLA Stxbp2 gene expression ENSRNOG00000000994 0.19 1 0.13 1.6e-07 -5.3 1.17e-07 0.64 FALSE
BLA Pet100 intron excision ratio chr12:1680794:1680963 0.36 13 0.19 1.7e-10 -5.8 6.58e-09 0.8 FALSE
BLA Pet100 intron excision ratio chr12:1680995:1681508 0.35 11 0.2 9.8e-11 5.78 7.26e-09 0.8 FALSE
BLA Cers4 mRNA stability ENSRNOG00000001072 0.16 2109 0.08 5.0e-05 5.42 5.90e-08 0.3 FALSE
BLA Stard13 mRNA stability ENSRNOG00000001090 0.08 1438 0.05 1.3e-03 5.25 1.52e-07 0.55 FALSE
Brain Pcp2 gene expression ENSRNOG00000000993 0.12 1 0.1 1.8e-09 5.39 7.02e-08 0.82 FALSE
Brain Elavl1 gene expression ENSRNOG00000001069 0.07 2406 0.02 4.4e-03 -5.66 1.50e-08 0.33 FALSE
Brain Arhgef18 gene expression ENSRNOG00000028090 0.12 11 0.08 1.2e-07 -5.83 5.58e-09 0.7 FALSE
Brain N4bp2l1 gene expression ENSRNOG00000059322 0.06 2 0.05 3.5e-05 -5.36 8.45e-08 0.9 FALSE
Brain Trappc5 intron excision ratio chr12:1737769:1740114 0.05 18 0.03 5.1e-04 -6.26 3.96e-10 0.63 TRUE
Brain Insr mRNA stability ENSRNOG00000029986 0.72 150 0.6 8.8e-69 5.19 2.10e-07 0.85 FALSE
Eye Elavl1 intron excision ratio chr12:2667464:2684652 0.69 30 0.31 1.3e-05 5.9 3.62e-09 0.25 FALSE
IL Snapc2 gene expression ENSRNOG00000001056 0.35 5 0.03 8.2e-02 -5.85 4.87e-09 0.36 FALSE
IL Cers4 gene expression ENSRNOG00000001072 0.3 1 0.08 7.0e-03 5.12 2.99e-07 0.07 FALSE
IL Insr intron excision ratio chr12:1257822:1307450 0.73 1 0.5 6.5e-14 5.48 4.35e-08 0.87 FALSE
IL N4bp2l2 mRNA stability ENSRNOG00000001108 0.16 1 0.08 4.7e-03 5.21 1.88e-07 0.5 FALSE
LHb Arhgef18 gene expression ENSRNOG00000028090 0.31 1 0.1 3.0e-03 -5.38 7.52e-08 0.09 FALSE
Liver N4bp2l2 alternative polyA ENSRNOT00000111844 0.1 681 0.07 2.3e-08 5.38 7.59e-08 0.58 FALSE
Liver N4bp2l2 alternative polyA ENSRNOT00000118063 0.1 681 0.07 1.5e-08 -5.41 6.42e-08 0.58 FALSE
Liver Mcoln1 gene expression ENSRNOG00000000975 0.09 39 0.04 1.7e-05 5.43 5.51e-08 0.83 FALSE
Liver Timm44 gene expression ENSRNOG00000001058 0.11 10 0.04 7.4e-05 5.71 1.11e-08 0.65 FALSE
Liver Stxbp2 isoform ratio ENSRNOT00000107607 0.15 10 0.09 5.9e-10 -5.68 1.38e-08 0.76 FALSE
Liver Stxbp2 isoform ratio ENSRNOT00000115749 0.1 1 0.05 6.9e-06 5.19 2.09e-07 0.46 FALSE
Liver N4bp2l1 isoform ratio ENSRNOT00000110394 0.06 587 0.04 6.9e-05 5.35 8.61e-08 0.59 FALSE
Liver Pet100 intron excision ratio chr12:1680794:1680963 0.21 1823 0.09 1.9e-10 -5.78 7.29e-09 0.74 FALSE
Liver Pet100 intron excision ratio chr12:1680995:1681508 0.18 152 0.07 3.1e-08 5.74 9.73e-09 0.6 FALSE
Liver Zfp958 intron excision ratio chr12:3953566:3958666 0.03 1113 0.01 1.1e-02 -5.6 2.18e-08 0.34 FALSE
Liver N4bp2l2 mRNA stability ENSRNOG00000001108 0.03 1 0.02 2.0e-03 5.36 8.45e-08 0.16 FALSE
NAcc Pet100 alternative TSS ENSRNOT00000071928 0.08 1 0.03 1.4e-03 5.32 1.02e-07 0.14 FALSE
NAcc Stxbp2 gene expression ENSRNOG00000000994 0.1 1 0.07 9.6e-06 -5.32 1.02e-07 0.31 FALSE
NAcc Cers4 gene expression ENSRNOG00000001072 0.27 26 0.27 5.9e-20 5.76 8.47e-09 0.59 FALSE
NAcc Arhgef18 gene expression ENSRNOG00000028090 0.13 1531 0.08 1.3e-06 -5.58 2.36e-08 0.49 FALSE
NAcc Lrrc8e gene expression ENSRNOG00000028460 0.31 12 0.07 1.2e-05 -5.6 2.17e-08 0.65 TRUE
NAcc Trappc5 isoform ratio ENSRNOT00000001327 0.11 38 0.04 2.9e-04 -5.69 1.31e-08 0.81 FALSE
NAcc Trappc5 isoform ratio ENSRNOT00000111016 0.09 29 0.03 5.1e-03 5.66 1.47e-08 0.78 FALSE
NAcc Snapc2 mRNA stability ENSRNOG00000001056 0.13 1 0.06 1.3e-05 -5.43 5.77e-08 0.76 FALSE
NAcc Brca2 mRNA stability ENSRNOG00000001111 0.14 42 0.09 4.2e-07 5.36 8.20e-08 0.9 FALSE
NAcc Insr mRNA stability ENSRNOG00000029986 0.37 29 0.23 1.8e-17 5.21 1.93e-07 0.84 FALSE
OFC Stxbp2 gene expression ENSRNOG00000000994 0.43 1 0.14 2.8e-04 -5.41 6.27e-08 0.08 FALSE
OFC Snapc2 gene expression ENSRNOG00000001056 0.54 2272 0.12 1.0e-03 -5.96 2.56e-09 0.49 TRUE
OFC Insr intron excision ratio chr12:1257822:1307450 0.64 1 0.28 2.2e-07 5.48 4.35e-08 0.7 FALSE
OFC Insr mRNA stability ENSRNOG00000029986 0.82 1 0.37 1.0e-09 5.32 1.02e-07 0.69 TRUE
PL Stxbp2 gene expression ENSRNOG00000000994 0.13 1819 0.06 2.6e-05 -5.82 5.96e-09 0.71 FALSE
PL Snapc2 gene expression ENSRNOG00000001056 0.47 50 0.28 8.7e-22 -5.14 2.82e-07 0.72 FALSE
PL Arhgef18 isoform ratio ENSRNOT00000066281 0.07 1 0.05 8.6e-05 5.3 1.19e-07 0.12 TRUE
PL Arhgef18 isoform ratio ENSRNOT00000110862 0.08 1 0.06 2.4e-05 -5.3 1.19e-07 0.26 FALSE
PL Snapc2 intron excision ratio chr12:2606007:2606962 0.06 1 0.04 2.5e-04 5.19 2.15e-07 0.34 FALSE
PL Snapc2 intron excision ratio chr12:2606335:2606962 0.18 1 0.16 6.0e-12 -5.21 1.91e-07 0.81 FALSE
PL Pet100 intron excision ratio chr12:1680794:1680963 0.49 1822 0.18 2.5e-13 -5.52 3.39e-08 0.44 FALSE
PL Pet100 intron excision ratio chr12:1680995:1681508 0.38 17 0.16 1.8e-12 5.26 1.43e-07 0.4 TRUE
PL Insr mRNA stability ENSRNOG00000029986 0.65 32 0.49 2.3e-42 5.23 1.71e-07 0.84 FALSE