Hub : Genes

Lcmt1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL intron excision ratio chr1_187389064_187390973 0.06 0.04 9.7e-06 0.04 0.04 0.03 0.03 4.8e-05 4.5e-05 1.9e-04 1.3e-04
2 NAcc gene expression Lcmt1 0.11 0.05 0.0e+00 0.12 0.11 0.1 0.11 1.8e-17 3.3e-16 2.9e-15 6.7e-16
3 Adipose mRNA stability Lcmt1 0.08 0.05 1.1e-05 0.04 0.02 0.01 0.03 8.2e-05 1.3e-03 8.5e-03 4.8e-04
4 Liver intron excision ratio chr1_187389064_187390973 0.05 0.03 1.3e-03 0.01 0.01 0 0.01 2.0e-02 1.4e-02 1.3e-01 4.7e-02
5 Adipose gene expression Lcmt1 0.12 0.06 1.2e-11 0.08 0.07 0.05 0.07 3.0e-09 7.6e-08 1.2e-06 1.1e-08
6 PL gene expression Lcmt1 0.04 0.03 8.9e-05 0.04 0.03 0.01 0.03 5.7e-05 2.4e-04 1.8e-02 2.2e-04
7 Liver intron excision ratio chr1_187382553_187383627 0.28 0.1 0.0e+00 0.14 0.14 0.14 0.14 2.0e-15 1.6e-15 5.6e-15 1.4e-15
8 Liver intron excision ratio chr1_187383524_187383627 0.27 0.1 0.0e+00 0.12 0.14 0.14 0.14 1.3e-13 1.6e-15 1.1e-15 1.2e-15
9 IC intron excision ratio chr1_187389064_187390973 0.11 0.07 4.5e-04 0.06 0.07 0.06 0.06 2.0e-03 6.6e-04 1.9e-03 1.4e-03
10 IL intron excision ratio chr1_187389064_187390973 0.3 0.16 2.4e-04 0.06 0.12 0.07 0.12 1.6e-02 9.6e-04 1.1e-02 1.0e-03
11 Liver mRNA stability Lcmt1 0.17 0.07 0.0e+00 0.09 0.09 0.1 0.09 7.2e-10 2.4e-10 2.9e-11 2.0e-10
12 Brain intron excision ratio chr1_187383718_187388967 0.04 0.03 5.8e-04 0.02 0.03 0.02 0.02 8.4e-03 1.1e-03 2.3e-03 6.0e-03
13 PL intron excision ratio chr1_187383718_187388967 0.05 0.03 1.9e-05 0.03 0.04 0.03 0.03 5.2e-04 7.5e-05 4.0e-04 2.7e-04
14 IL intron excision ratio chr1_187383718_187388967 0.28 0.14 1.3e-04 0.06 0.15 0.12 0.1 1.3e-02 2.3e-04 7.1e-04 2.2e-03
15 NAcc intron excision ratio chr1_187389064_187390973 0.05 0.03 2.8e-08 0.04 0.05 0.05 0.04 5.4e-07 3.3e-08 7.1e-08 7.4e-07
16 IC intron excision ratio chr1_187383718_187388967 0.11 0.08 2.5e-03 0.04 0.05 0.03 0.04 1.1e-02 3.0e-03 2.2e-02 6.3e-03
17 Brain mRNA stability Lcmt1 0.14 0.07 6.1e-11 0.12 0.11 0.11 0.11 3.6e-11 2.7e-10 1.7e-10 1.8e-10
18 PL isoform ratio XM_006230191.5 0.03 0.02 6.7e-03 0.01 0.01 0.01 0.01 1.9e-02 1.0e-02 8.6e-03 3.4e-02
19 PL isoform ratio NM_199405.3 0.03 0.02 6.3e-03 0.01 0.01 0.01 0.01 2.6e-02 9.3e-03 8.3e-03 3.0e-02
20 Adipose intron excision ratio chr1_187383718_187388967 0.03 0.02 5.2e-03 0.02 0.01 0.01 0.01 1.9e-03 8.2e-03 1.1e-02 6.9e-03
21 Brain intron excision ratio chr1_187389064_187390973 0.07 0.04 5.9e-06 0.04 0.05 0.05 0.05 8.1e-05 2.2e-05 1.2e-05 1.7e-05
22 NAcc intron excision ratio chr1_187383718_187388967 0.04 0.03 7.1e-05 0.02 0.02 0.03 0.02 3.3e-04 1.1e-04 2.3e-05 1.8e-04
23 PL mRNA stability Lcmt1 0.05 0.03 5.4e-04 0.03 0.03 0.01 0.02 8.9e-04 8.8e-04 8.7e-03 7.0e-03
24 LHb mRNA stability Lcmt1 0.34 0.17 2.4e-03 0.04 0.08 0.01 0.03 4.8e-02 6.7e-03 1.7e-01 6.8e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density0.50.91.61.0-0.8-1.20.8-1.1-0.81.2-1.11.01.11.3-1.0-1.1-1.11.0-1.00.8-0.10.20.61.2-1.00.7-0.0
Area under the delay curve0.10.10.60.00.10.1-0.2-0.10.1-0.0-0.40.10.20.10.1-0.3-0.3-0.1-0.20.50.3-0.00.50.0-0.00.70.8
BMI with tail3.411.816.63.6-4.0-3.63.0-3.6-3.33.2-3.34.04.03.3-3.5-4.1-4.13.5-3.94.0-2.01.63.84.0-2.83.20.8
BMI without tail4.814.620.04.1-4.5-4.03.3-4.0-4.03.8-3.74.34.43.9-3.9-4.4-4.43.9-4.34.4-2.11.74.34.1-3.23.20.5
Body weight2.912.819.14.1-4.4-4.24.0-4.1-3.93.9-3.93.93.93.7-3.9-3.7-3.63.8-3.73.1-3.43.32.83.3-2.71.7-0.8
Weight adjusted by age0.50.71.90.8-0.7-0.80.2-0.8-0.70.5-1.00.80.80.7-0.5-1.1-0.90.5-0.81.4-0.2-0.21.41.30.21.21.0
Bone surface1.01.84.51.6-1.3-1.51.4-1.6-1.21.7-2.11.41.41.7-1.3-1.5-1.41.1-1.31.3-0.70.81.21.3-0.91.10.4
Bone volume1.42.64.51.8-1.6-1.81.5-1.8-1.62.0-2.11.71.82.0-1.6-1.9-1.71.5-1.71.7-0.70.71.61.7-1.11.40.4
Breakpoint value in progressive ratio session0.20.20.8-0.40.40.2-0.40.30.40.00.6-0.5-0.5-0.10.20.60.5-0.20.4-0.90.4-0.3-0.9-0.50.1-0.8-0.9
Number of licking bursts3.65.813.9-2.92.42.8-3.42.82.9-2.82.0-2.0-1.9-2.22.91.31.4-2.81.8-0.13.3-3.7-0.1-0.42.11.33.3
Context. condit. distance diff. score0.40.42.0-0.60.50.5-0.90.50.6-0.90.3-0.3-0.1-0.70.7-0.00.0-0.70.20.50.8-1.30.6-0.00.60.81.4
Locomotion velocity, session 10.20.20.70.50.2-0.40.2-0.5-0.40.7-0.80.40.40.8-0.3-0.6-0.40.3-0.40.50.3-0.10.50.30.00.50.4
Locomotion distance, session 10.20.30.50.6-0.3-0.70.4-0.6-0.50.6-0.60.60.60.6-0.6-0.6-0.60.5-0.60.5-0.10.10.40.7-0.20.50.1
Locomotion velocity, session 20.40.51.30.6-0.2-0.70.3-0.6-0.60.6-1.20.60.70.7-0.3-0.9-0.70.2-0.61.1-0.10.11.20.10.31.01.0
Locomotion distance, session 20.50.71.10.9-0.8-0.80.8-0.8-0.80.9-1.00.90.91.0-0.9-0.9-0.90.9-0.90.8-0.20.10.61.0-1.00.7-0.0
Locomotion velocity, session 31.01.12.61.1-1.6-0.91.5-1.0-1.11.1-1.31.01.01.0-1.0-0.9-0.91.0-0.90.9-1.61.60.80.6-0.40.4-0.2
Locomotion distance, session 30.10.10.6-0.1-0.40.30.20.30.00.1-0.4-0.1-0.20.10.40.10.2-0.40.30.4-0.50.40.3-0.30.80.20.6
Stereotopy head waving bouts, day 30.40.42.40.20.0-0.20.2-0.3-0.00.60.40.20.20.6-0.70.1-0.10.7-0.4-1.10.7-0.2-0.90.6-1.4-0.7-1.6
Stereotopy head waving duration, day 30.30.41.70.5-0.2-0.60.5-0.7-0.30.9-0.20.50.50.9-0.8-0.3-0.40.8-0.6-0.50.40.1-0.30.8-1.3-0.2-1.0
Locomotion velocity, session 70.40.42.30.5-0.1-0.70.8-0.7-0.70.1-0.70.0-0.00.0-0.30.20.20.30.2-0.4-1.51.2-0.4-0.30.4-1.0-0.9
Locomotion distance, session 70.40.51.9-0.61.20.5-0.80.50.7-0.80.1-0.6-0.5-0.60.90.30.4-0.90.60.30.8-1.10.0-0.20.90.51.4
Stereotopy head waving bouts, day 70.20.20.80.4-0.7-0.40.6-0.4-0.40.5-0.30.20.20.4-0.4-0.0-0.10.5-0.2-0.4-0.60.6-0.20.0-0.4-0.5-0.9
Stereotopy head waving duration, day 70.81.01.71.1-1.3-1.11.3-1.1-1.11.2-1.00.90.91.1-1.2-0.7-0.71.1-0.80.2-1.11.20.20.7-0.9-0.2-1.0
Locomotion velocity, session 80.10.10.50.3-0.5-0.30.4-0.4-0.50.4-0.40.40.40.4-0.3-0.3-0.40.3-0.40.2-0.00.00.30.1-0.70.2-0.1
Locomotion distance, session 80.20.32.0-0.00.1-0.0-0.20.00.1-0.2-0.40.20.3-0.10.2-0.5-0.5-0.2-0.20.90.5-0.80.80.50.21.21.4
Degree of sensitization distance0.50.52.7-0.61.10.4-1.10.40.6-0.91.0-0.3-0.2-0.70.40.20.1-0.30.1-0.21.5-1.6-0.20.3-0.40.30.4
Degree of sensitization stereotypy0.20.31.20.5-0.9-0.50.8-0.5-0.60.5-0.60.30.30.3-0.4-0.2-0.20.4-0.20.0-1.10.90.1-0.0-0.1-0.4-0.6
Conditioned locomotion0.20.20.6-0.20.40.30.10.20.5-0.1-0.1-0.4-0.5-0.30.30.50.5-0.30.5-0.5-0.50.6-0.8-0.60.0-0.6-0.3
Cocaine response after cond. corrected0.70.91.7-1.11.21.0-1.31.01.1-1.10.8-0.9-0.8-1.01.10.70.7-1.00.8-0.21.2-1.3-0.2-0.80.80.20.9
Cocaine response after cond. not corrected0.00.00.10.2-0.1-0.30.1-0.3-0.2-0.0-0.20.10.1-0.0-0.2-0.1-0.10.1-0.10.0-0.30.10.0-0.20.1-0.2-0.2
Cocaine response before conditioning3.74.58.32.6-2.7-2.72.7-2.6-2.92.2-2.12.02.01.9-2.4-1.7-1.62.3-1.71.0-2.92.61.11.2-1.3-0.2-1.6
Saline control response0.20.32.3-0.50.40.6-0.80.50.4-0.10.8-0.3-0.2-0.10.40.10.1-0.40.1-0.01.5-1.40.0-0.20.20.40.6
Bone: connectivity density0.10.20.60.4-0.4-0.40.2-0.4-0.10.6-0.70.40.40.6-0.3-0.5-0.50.3-0.50.40.2-0.10.30.8-0.40.60.4
Bone: cortical apparent density0.71.01.8-1.11.11.1-1.31.21.0-1.10.9-0.8-0.8-0.91.20.60.6-1.20.80.31.2-1.30.2-0.51.00.41.3
Bone: cortical area3.96.09.52.6-2.6-2.52.3-2.6-2.62.7-3.12.72.72.8-2.2-2.8-2.72.2-2.63.1-1.21.23.02.3-1.62.31.0
Bone: cortical porosity1.82.08.01.5-1.9-1.42.3-1.4-1.51.3-1.81.10.91.1-1.2-0.7-0.71.1-0.70.4-2.82.80.30.5-0.1-0.4-0.9
Bone: cortical porosity1.41.57.41.2-1.6-1.12.0-1.1-1.31.1-1.20.70.50.8-1.0-0.2-0.20.9-0.3-0.3-2.72.7-0.40.0-0.0-1.0-1.5
Bone: cortical thickness1.62.76.61.3-1.7-1.21.1-1.3-1.31.5-2.01.71.71.7-1.1-2.0-1.91.1-1.72.6-0.30.32.51.8-0.82.31.6
Bone: cortical thickness0.50.62.50.3-0.7-0.20.2-0.3-0.50.4-0.90.70.70.5-0.1-0.9-0.80.1-0.61.60.3-0.51.60.50.11.51.5
Bone: cortical tissue density0.81.01.9-1.21.21.1-1.41.31.1-1.21.0-0.9-0.9-1.01.20.60.7-1.20.80.21.3-1.30.1-0.51.00.41.2
Condit. Reinf. active minus inactive responses0.10.10.4-0.20.40.2-0.50.20.3-0.30.2-0.3-0.2-0.20.30.10.2-0.30.3-0.10.1-0.2-0.1-0.20.70.10.3
Condit. Reinf. active-inactive response ratio0.20.21.10.10.0-0.20.0-0.20.10.00.1-0.2-0.2-0.0-0.20.30.30.20.2-0.9-0.60.6-1.0-0.40.0-0.9-1.0
Condit. Reinf. active responses0.30.42.5-0.30.60.3-0.80.30.4-0.20.1-0.00.00.10.4-0.4-0.3-0.5-0.10.91.0-0.90.70.40.81.31.6
Condit. Reinf. inactive responses1.01.26.5-0.20.50.3-0.80.40.20.0-0.10.40.40.30.4-0.9-0.7-0.5-0.51.91.7-1.61.81.00.52.32.5
Incentive salience index mean0.30.30.70.5-0.3-0.50.3-0.4-0.50.5-0.80.40.40.5-0.3-0.6-0.50.2-0.30.8-0.80.80.70.40.80.70.7
Condit. Reinf. lever presses1.11.53.41.2-0.9-1.11.0-1.0-1.01.2-1.81.11.11.3-0.8-1.5-1.20.6-1.01.8-1.21.21.71.20.71.61.4
Condit. Reinf. active minus inactive responses0.60.82.90.40.1-0.3-0.2-0.30.10.70.10.80.81.0-0.5-1.1-1.00.5-1.01.21.5-1.01.11.7-0.61.71.1
Condit. Reinf. active-inactive response ratio1.31.56.6-0.40.50.4-1.20.50.8-0.10.50.40.40.40.3-1.0-0.9-0.3-0.71.72.4-2.11.61.50.02.62.5
Condit. Reinf. active responses0.20.31.60.10.10.1-0.20.10.10.40.20.40.30.6-0.1-0.6-0.60.1-0.50.81.1-0.60.71.1-0.21.30.9
Condit. Reinf. inactive responses0.30.42.00.5-0.5-0.31.0-0.3-0.60.5-0.40.1-0.00.3-0.40.10.20.40.0-0.6-1.31.4-0.6-0.1-0.2-0.8-1.0
Condit. Reinf. lever presses1.01.42.41.2-1.0-1.00.8-1.0-1.11.4-0.91.31.31.5-1.1-1.5-1.41.0-1.41.50.10.11.41.5-0.81.50.7
Condit. Reinf. lever reinforcers received0.20.31.6-0.10.30.3-0.50.30.30.20.40.20.10.40.1-0.4-0.4-0.1-0.30.71.3-0.90.60.80.01.21.1
Conditioned reinforcement - actives0.40.71.6-0.90.60.7-0.70.80.7-0.80.9-1.0-0.9-0.80.71.11.0-0.60.9-1.30.2-0.4-1.2-1.10.2-1.2-0.8
Conditioned reinforcement - inactives0.50.81.9-1.11.11.2-1.40.81.2-0.60.8-0.9-0.8-0.50.90.80.7-0.80.7-0.71.4-1.4-0.7-0.40.5-0.20.2
Conditioned locomotion1.31.73.0-1.31.01.2-1.01.01.1-1.21.1-1.5-1.5-1.21.21.61.6-1.21.6-1.7-0.20.1-1.7-1.71.7-1.6-0.6
Patch foraging indifference point 0 sec0.81.62.81.4-0.9-1.51.0-1.3-1.41.4-0.51.41.61.4-1.6-1.4-1.51.5-1.51.10.2-0.20.91.7-1.70.8-0.5
Patch foraging indifference point AUC0.71.02.70.9-1.6-0.80.7-0.9-1.40.8-0.31.21.20.9-1.1-1.0-1.21.2-1.31.0-0.40.31.21.2-1.20.7-0.4
Delay disc. indifference point, 0s delay0.40.41.30.6-0.7-0.60.5-0.7-0.60.5-0.50.70.80.5-0.7-0.7-0.80.8-0.80.7-0.20.30.70.7-1.20.5-0.1
Delay disc. indifference point, 16s delay1.21.32.2-1.31.41.4-1.31.11.5-1.40.7-1.0-1.0-1.31.50.90.9-1.41.0-0.31.5-1.4-0.3-0.90.90.21.3
Delay disc. indifference point, 2s delay3.94.46.12.4-2.2-2.22.0-2.2-2.22.5-2.12.32.32.4-2.4-2.4-2.42.4-2.42.0-1.41.72.01.5-1.71.6-0.3
Delay disc. indifference point, 24s delay0.40.50.9-0.80.80.8-1.00.60.8-0.90.6-0.7-0.6-0.90.80.60.6-0.80.7-0.50.7-0.6-0.5-0.70.6-0.20.3
Delay disc. indifference point, 4s delay0.20.21.3-0.10.00.1-0.30.20.1-0.1-0.40.20.20.10.2-0.4-0.4-0.1-0.20.90.4-0.30.9-0.1-0.41.01.1
Delay disc. indifference point, 8s delay0.10.10.40.20.0-0.00.1-0.20.00.3-0.60.10.10.4-0.0-0.2-0.10.0-0.10.2-0.20.70.20.10.20.40.4
Indifference point function ln k1.11.93.01.6-1.0-1.61.4-1.5-1.21.4-1.71.51.61.4-1.3-1.7-1.61.3-1.41.7-0.70.61.41.2-0.91.50.8
Indifference point function log k1.11.93.01.6-1.0-1.61.4-1.5-1.21.4-1.71.51.61.4-1.3-1.7-1.61.3-1.41.7-0.70.61.41.2-0.91.50.8
Patch foraging total patch changes 0 sec1.01.83.31.4-0.9-1.50.8-1.3-1.31.3-0.51.61.71.4-1.6-1.6-1.71.6-1.71.30.5-0.51.11.8-1.81.1-0.2
Patch foraging total patch changes 12 sec0.10.10.7-0.20.10.1-0.50.2-0.1-0.10.7-0.00.1-0.0-0.10.0-0.10.1-0.1-0.10.8-0.8-0.10.5-0.5-0.0-0.4
Patch foraging total patch changes 18 sec0.10.10.9-0.30.10.2-0.70.30.1-0.20.9-0.1-0.0-0.20.00.1-0.00.0-0.1-0.10.9-0.90.20.3-0.40.1-0.1
Patch foraging total patch changes 24 sec0.20.31.30.2-0.1-0.2-0.3-0.1-0.30.30.40.50.60.5-0.4-0.6-0.70.4-0.70.71.1-1.00.51.0-0.70.80.2
Patch foraging total patch changes 6 sec0.40.61.80.3-0.7-0.3-0.2-0.2-0.60.60.60.70.80.7-0.7-0.7-0.90.8-1.00.61.2-1.00.71.0-1.40.7-0.3
Patch foraging time to switch 0 sec2.34.77.7-2.22.52.0-1.92.12.3-2.21.5-2.6-2.6-2.32.52.42.6-2.62.7-2.20.4-0.6-2.1-2.62.8-1.70.4
Patch foraging water rate 0 sec0.71.42.51.2-1.1-1.20.8-1.2-1.11.2-1.01.31.51.3-1.2-1.4-1.51.2-1.41.60.00.01.31.4-1.01.20.3
Patch foraging water rate 12 sec0.51.13.60.7-0.9-0.50.5-0.7-0.60.7-1.01.11.20.9-0.6-1.3-1.30.6-1.11.90.3-0.31.71.0-0.61.81.4
Patch foraging water rate 18 sec0.71.01.81.1-1.3-1.01.2-1.1-0.90.9-1.01.21.20.8-0.9-1.1-1.21.0-1.11.3-0.70.41.10.7-1.00.80.3
Patch foraging water rate 24 sec1.01.53.81.1-1.0-0.90.7-1.1-0.81.1-1.51.31.41.1-0.9-1.6-1.50.9-1.31.90.0-0.21.90.8-0.61.81.3
Patch foraging water rate 6 sec0.50.72.30.1-0.30.0-0.4-0.0-0.10.2-0.00.60.70.5-0.3-0.8-0.90.3-0.81.21.5-1.51.10.8-0.81.51.1
Seeking ratio, delayed vs. immediate footshock0.40.52.0-0.40.50.50.00.30.6-0.70.1-0.7-0.8-0.80.80.80.9-0.80.9-0.7-0.90.7-0.7-1.01.4-0.80.1
Distance traveled before self-admin0.60.71.3-0.90.81.0-0.61.00.9-0.60.8-1.0-1.1-0.60.91.01.0-0.91.0-1.0-0.10.6-1.0-1.11.1-0.7-0.1
Distance traveled after self-admin0.70.91.5-1.01.11.1-0.81.11.0-0.30.6-1.2-1.2-0.30.91.11.1-0.91.1-1.20.10.5-1.2-0.91.2-0.7-0.3
Extensor digitorum longus weight4.618.129.55.0-5.4-5.15.1-5.0-5.24.8-4.94.34.24.6-4.6-3.9-3.84.5-3.92.9-5.04.92.82.9-2.81.0-1.8
Bone: elastic displacement0.80.93.4-0.70.40.5-0.30.50.6-0.51.1-0.9-0.9-0.70.41.31.1-0.30.8-1.70.00.2-1.7-0.9-0.3-1.8-1.8
Bone: elastic work0.10.20.70.4-0.4-0.40.4-0.5-0.20.9-0.50.40.30.8-0.5-0.3-0.30.5-0.4-0.00.10.2-0.20.4-0.8-0.0-0.5
Bone: endosteal estimation1.53.25.32.1-2.1-2.11.9-2.1-2.32.2-2.21.91.92.1-1.9-1.9-1.81.8-1.81.6-1.21.11.51.3-1.60.8-0.3
Bone: endosteal perimeter0.91.93.91.7-1.5-1.71.7-1.8-1.71.6-2.01.31.41.5-1.4-1.3-1.21.4-1.11.0-1.61.30.90.5-0.80.2-0.5
Epididymis fat weight1.03.44.62.0-1.9-2.01.7-2.0-1.91.7-2.02.12.11.8-1.9-2.1-2.11.9-2.02.1-1.31.21.92.0-1.21.50.3
Delta time in closed arm before/after self-admin0.80.82.4-0.70.60.7-0.30.80.6-0.80.1-1.0-1.1-1.01.01.01.1-1.01.2-0.8-0.70.5-0.8-1.11.5-0.80.1
Delta time in open arm before/after self-admin3.93.96.22.0-1.9-1.91.4-2.0-1.92.2-1.32.32.42.4-2.2-2.3-2.42.2-2.52.00.10.32.02.4-2.31.7-0.1
Diff in mean of infusions in LGA sessions0.20.31.2-0.10.10.0-0.40.20.10.00.30.20.30.20.0-0.4-0.4-0.1-0.40.71.1-1.10.70.9-0.40.90.8
Delay discount exponential model param0.10.10.50.1-0.2-0.20.20.0-0.20.10.4-0.0-0.00.0-0.20.20.10.20.0-0.3-0.2-0.1-0.30.2-0.1-0.5-0.7
Extinction: sum of active levers before priming0.40.40.9-0.60.70.7-0.80.40.7-0.30.9-0.7-0.7-0.40.40.70.7-0.40.6-0.90.7-0.8-1.0-0.70.1-0.8-0.6
Active lever presses in extinction session 61.41.42.31.4-1.3-1.31.3-1.4-1.31.5-1.21.31.21.3-1.4-1.1-1.11.4-1.20.8-1.11.20.70.8-1.10.3-0.6
Bone: final force5.08.012.03.0-3.0-2.92.8-3.0-3.03.4-3.33.13.13.5-2.8-3.2-3.12.7-3.02.9-1.21.52.92.9-2.32.40.5
Bone: final moment4.57.211.12.9-2.7-2.82.6-2.9-2.83.3-3.13.03.03.3-2.7-3.0-3.02.6-2.92.8-0.91.32.82.7-2.32.30.4
Food consumed during 24 hour testing period1.31.82.91.3-1.5-1.11.0-1.2-1.51.4-1.21.51.51.6-1.3-1.5-1.61.4-1.61.6-0.10.11.71.7-1.61.30.2
Glucose0.40.73.20.7-0.9-0.70.5-0.8-1.10.5-0.00.80.90.6-1.1-0.5-0.81.2-0.90.3-0.40.10.31.1-1.8-0.2-1.3
Heart weight0.61.01.91.1-1.1-1.40.9-1.3-1.10.8-0.81.21.30.8-1.2-1.1-1.21.2-1.20.9-0.50.20.80.7-0.90.5-0.3
Delay discount hyperbolic model param0.10.10.5-0.30.10.1-0.10.30.1-0.20.6-0.3-0.4-0.30.20.50.5-0.20.3-0.6-0.0-0.3-0.6-0.10.2-0.7-0.7
Intermittent access intake day 1-15 change0.40.92.6-1.11.21.3-1.60.81.2-0.90.7-0.8-0.6-0.91.00.50.5-0.90.6-0.21.5-1.5-0.2-0.80.30.30.8
Intermittent access intake escalation0.30.72.2-1.01.11.1-1.50.71.1-0.80.5-0.6-0.5-0.80.90.40.3-0.80.4-0.01.4-1.4-0.0-0.60.30.40.9
Intermittent access intake escalation 20.70.82.3-1.01.11.2-1.40.61.2-0.80.4-0.7-0.6-0.90.90.50.5-0.90.6-0.21.4-1.5-0.2-0.90.40.20.8
Intermitt. access day 1 inactive lever presses0.20.82.8-0.91.01.0-1.40.81.0-0.70.9-0.5-0.4-0.40.80.10.1-0.80.30.31.7-1.70.30.50.41.01.3
Intermitt. access day 15 inactive lever presses0.30.61.10.9-0.7-0.60.7-0.9-0.71.0-1.10.80.81.0-0.7-1.0-0.80.6-0.71.0-0.80.61.00.8-0.10.90.5
Intermitt. access escalation Index0.10.10.20.2-0.2-0.10.1-0.3-0.10.2-0.10.40.30.2-0.2-0.4-0.40.2-0.40.40.5-0.40.40.2-0.40.40.2
Intermittent access day 1 total infusions0.10.10.8-0.1-0.3-0.2-0.30.4-0.3-0.10.9-0.00.00.2-0.0-0.1-0.1-0.0-0.10.10.2-0.10.10.20.80.1-0.1
Intermittent access day 15 total infusions0.50.82.6-1.00.81.0-1.60.90.9-0.91.1-0.6-0.5-0.70.90.30.3-0.80.40.11.5-1.40.2-0.40.90.61.0
Intermittent access terminal intake (last 3 days)0.20.31.4-0.60.40.6-1.20.50.5-0.40.9-0.3-0.2-0.20.40.10.1-0.40.10.11.1-1.00.1-0.20.70.40.5
Intermittent access total infusions0.10.10.30.1-0.4-0.2-0.10.1-0.30.30.30.20.30.4-0.1-0.3-0.30.1-0.20.40.10.00.40.20.50.40.2
Intermittent access day 1 locomotion0.10.21.2-0.2-0.00.1-0.50.40.1-0.10.3-0.10.00.20.3-0.2-0.1-0.40.00.60.3-0.30.60.21.10.71.0
Intermittent access day 15 total locomotion0.30.62.4-0.60.60.6-1.20.60.6-0.40.6-0.2-0.1-0.10.6-0.2-0.1-0.60.00.91.5-1.40.9-0.10.91.21.6
Intermittent access total locomotion0.40.51.60.4-0.7-0.50.0-0.2-0.50.5-0.10.60.70.8-0.4-0.9-0.80.3-0.71.20.2-0.21.20.70.41.10.9
Intermittent access standard deviation0.10.30.90.3-0.3-0.2-0.3-0.5-0.30.3-0.20.50.70.4-0.3-0.7-0.80.4-0.60.90.4-0.60.90.5-0.30.90.6
Left kidney weight3.918.228.75.0-5.2-5.25.4-5.1-4.84.5-4.64.54.44.1-4.7-3.9-4.04.6-4.12.9-5.04.72.83.5-3.21.0-1.9
Right kidney weight3.716.824.74.8-4.9-4.95.0-4.8-4.74.3-4.04.44.44.0-4.6-3.9-4.04.6-4.22.9-4.24.02.83.9-3.51.3-1.7
Cocaine induced anxiety0.30.40.8-0.70.90.9-0.80.50.9-0.70.5-0.6-0.6-0.70.70.40.5-0.70.5-0.30.5-0.6-0.3-0.50.80.10.6
Post-drug Anxiety0.00.00.10.10.00.00.2-0.20.00.00.10.10.0-0.1-0.10.0-0.00.2-0.1-0.2-0.1-0.0-0.20.1-0.4-0.2-0.3
Baseline Anxiety1.01.22.21.2-1.4-1.31.5-1.2-1.31.2-0.81.11.11.0-1.3-0.8-0.91.3-1.00.5-1.01.00.50.9-1.5-0.2-1.1
Tail length1.14.27.12.5-2.2-2.72.3-2.6-2.52.5-2.12.12.22.3-2.4-1.9-2.02.3-2.01.5-1.41.31.21.9-2.00.4-1.2
Length with tail0.62.57.91.7-1.7-1.92.4-1.8-1.81.9-1.71.00.91.3-1.5-0.4-0.41.4-0.7-0.3-2.72.8-0.60.1-0.6-1.5-2.2
Length without tail0.41.24.90.4-0.6-0.51.3-0.4-0.50.3-0.3-0.2-0.4-0.2-0.30.80.70.20.5-1.4-2.12.2-1.6-0.90.3-2.1-2.1
Times rat made contact with spout0.20.21.2-0.3-0.40.3-0.40.30.10.1-0.5-0.1-0.10.20.4-0.2-0.0-0.40.10.70.3-0.50.7-0.40.30.81.1
Lifetime Intake0.10.10.30.1-0.5-0.30.00.1-0.40.20.50.10.20.3-0.3-0.2-0.20.2-0.20.1-0.10.30.20.30.30.0-0.3
Liver weight, left0.30.52.90.4-0.7-0.70.1-0.7-0.9-0.00.80.50.7-0.2-0.9-0.2-0.51.0-0.6-0.2-0.2-0.2-0.10.0-1.5-0.8-1.7
Liver weight, right0.30.42.80.5-0.4-0.60.5-0.8-0.60.20.00.20.4-0.1-0.70.1-0.10.7-0.2-0.7-1.00.7-0.7-0.2-0.7-1.2-1.7
Locomotor activity0.40.64.80.3-0.3-0.20.6-0.4-0.30.60.1-0.0-0.10.3-0.60.50.30.7-0.0-1.1-0.81.1-1.2-0.1-1.0-1.5-2.2
Locomotor testing distance0.10.10.60.2-0.3-0.20.0-0.2-0.30.20.30.20.30.1-0.4-0.1-0.20.4-0.3-0.1-0.0-0.0-0.10.3-0.7-0.3-0.8
Locomotor testing rearing1.02.03.7-1.61.41.6-1.81.51.6-1.61.9-1.4-1.3-1.61.31.41.2-1.31.2-1.21.5-1.7-1.3-1.20.8-0.9-0.1
Locomotion in novel chamber0.81.03.10.6-0.6-0.70.3-0.6-0.60.5-0.51.01.10.8-0.6-1.2-1.20.6-1.11.70.7-0.91.81.1-0.71.61.2
Locomotion in novel chamber post-restriction1.52.48.5-1.81.61.7-2.21.91.7-1.51.5-1.2-1.1-1.11.70.80.8-1.61.0-0.02.9-2.90.0-0.31.10.91.9
Fecal boli incidents, locomotor time 11.11.63.3-1.21.01.0-0.90.81.1-1.41.2-1.4-1.3-1.51.01.61.5-1.01.4-1.80.1-0.6-1.8-1.50.4-1.8-1.1
Change in fecal boli incidents, locomotor task1.51.43.21.2-1.3-1.21.4-0.9-1.21.3-1.31.31.11.4-1.1-1.3-1.21.0-1.21.3-1.21.81.31.1-0.11.10.4
Time >=10cm from walls, locomotor time 10.50.51.0-0.60.70.7-0.50.70.8-0.40.5-0.8-0.9-0.40.60.80.9-0.60.8-1.00.5-0.4-1.0-1.0-0.2-0.7-0.4
Bouts of movement, locomotor time 10.10.10.4-0.30.40.3-0.40.20.1-0.60.5-0.4-0.3-0.60.30.40.4-0.30.4-0.5-0.1-0.1-0.5-0.0-0.0-0.6-0.3
Total resting periods, locomotor time 10.10.10.3-0.30.30.2-0.30.10.1-0.50.4-0.3-0.3-0.60.30.40.4-0.30.4-0.4-0.3-0.0-0.4-0.10.0-0.5-0.2
Rest time, locomotor task time 10.50.71.2-0.60.50.6-0.30.50.5-0.70.2-0.9-0.9-0.80.91.01.1-0.91.1-1.0-1.00.9-1.0-1.01.0-1.1-0.2
Distance moved, locomotor task time 11.01.64.40.8-0.6-0.80.1-0.7-0.60.8-0.41.31.41.1-0.9-1.6-1.60.9-1.51.91.5-1.31.91.3-1.22.11.2
Vertical activity count, locomotor time 10.41.02.10.7-0.5-0.70.1-0.8-0.60.70.01.11.21.0-1.0-1.2-1.41.0-1.41.11.2-0.91.11.5-1.01.40.4
Time >=10cm from walls, locomotor time 20.10.20.80.1-0.3-0.20.40.0-0.20.20.2-0.1-0.2-0.0-0.20.30.30.20.2-0.6-0.60.4-0.6-0.6-0.3-0.7-0.9
Bouts of movement, locomotor time 20.40.62.7-0.60.90.6-1.00.80.6-0.30.0-0.6-0.5-0.10.90.10.4-1.00.60.51.2-1.20.5-0.31.50.81.7
Total resting periods, locomotor time 20.20.42.1-0.30.70.4-0.60.50.3-0.1-0.3-0.3-0.30.00.7-0.10.2-0.80.40.60.7-0.80.6-0.21.30.71.4
Rest time, locomotor task time 20.30.42.20.4-0.8-0.50.8-0.5-0.60.2-0.60.20.20.1-0.40.1-0.00.5-0.1-0.3-1.51.1-0.40.4-0.8-0.7-0.9
Distance moved, locomotor task time 20.70.83.8-0.50.90.6-1.20.60.7-0.40.6-0.1-0.0-0.10.5-0.4-0.3-0.6-0.11.01.9-1.60.90.00.61.61.8
Vertical activity count, locomotor time 20.50.64.0-0.81.00.9-1.20.70.9-0.71.3-0.4-0.4-0.40.40.30.2-0.40.1-0.32.0-1.5-0.30.10.30.50.3
Light reinforcement 10.81.94.8-1.31.21.2-0.61.40.9-1.11.6-1.5-1.6-1.41.11.91.8-1.11.5-2.20.20.1-2.0-1.10.3-2.0-1.4
Light reinforcement 20.10.10.60.3-0.1-0.40.5-0.3-0.40.20.00.20.20.2-0.3-0.1-0.10.2-0.1-0.2-0.70.7-0.20.8-0.2-0.2-0.3
Bone: marrow area1.53.25.22.1-2.1-2.11.9-2.1-2.32.1-2.11.91.92.1-1.9-1.9-1.81.8-1.81.6-1.21.11.51.3-1.50.9-0.3
Bone: maximum diameter2.75.17.22.5-2.7-2.42.4-2.6-2.62.6-2.72.52.52.5-2.3-2.4-2.42.3-2.32.3-1.51.42.41.9-1.91.50.0
Bone: maximum force4.37.712.03.1-2.9-3.02.8-3.0-3.03.4-3.33.03.03.5-2.8-3.1-3.02.7-2.92.7-1.21.62.82.7-2.32.20.3
Bone: maximum moment3.96.810.92.9-2.6-2.82.6-2.9-2.83.3-3.12.92.83.3-2.7-2.9-2.82.6-2.82.6-1.01.32.62.5-2.32.00.3
Mean time between licks in bursts0.92.25.5-1.51.01.5-1.51.61.3-1.42.4-1.6-1.6-1.31.01.81.6-0.91.3-2.20.9-0.8-2.3-0.90.4-1.8-1.6
Mean num. licks in bursts2.33.68.32.2-2.1-2.12.6-2.1-2.32.4-1.81.51.42.0-2.2-1.0-1.02.2-1.30.3-2.52.90.2-0.1-1.8-1.0-2.6
Cd content in liver0.90.92.1-1.30.91.4-1.41.40.9-0.91.2-1.0-1.0-0.71.00.80.8-1.00.8-0.41.5-1.3-0.3-0.50.70.00.4
Co content in liver1.72.03.51.6-1.2-1.51.5-1.6-1.81.9-1.71.51.51.7-1.4-1.5-1.51.3-1.51.6-0.61.11.51.3-0.81.10.2
Cu content in liver1.61.94.31.2-1.1-1.21.2-1.2-1.11.5-1.81.41.31.7-0.9-1.6-1.40.9-1.32.0-0.50.92.11.4-0.01.81.3
Fe content in liver0.30.42.0-0.60.40.6-1.00.60.6-0.51.0-0.2-0.1-0.40.40.1-0.1-0.3-0.00.41.4-1.30.3-0.0-0.00.60.6
K content in liver3.13.05.61.9-1.8-1.82.1-1.9-1.72.0-2.41.81.62.0-1.5-1.8-1.51.5-1.61.9-1.82.21.91.5-0.31.10.4
Mg content in liver1.21.24.21.3-1.1-1.41.7-1.4-1.01.2-1.50.90.81.0-1.1-0.6-0.51.0-0.60.4-2.02.10.10.5-0.0-0.5-0.9
Mn content in liver0.60.71.20.9-1.1-1.00.9-1.0-0.90.9-1.00.90.90.9-0.9-0.8-0.80.9-0.80.7-0.70.50.80.4-0.90.2-0.3
Na content in liver3.73.97.92.3-2.2-2.32.8-2.3-1.92.3-2.81.91.82.1-2.1-1.6-1.52.0-1.61.1-2.62.81.11.6-1.10.2-1.0
Rb content in liver0.30.31.8-0.3-0.30.3-0.60.30.20.00.70.20.20.10.1-0.3-0.40.0-0.40.71.3-1.10.60.6-0.20.90.6
Se content in liver0.10.10.9-0.00.2-0.1-0.2-0.10.10.1-0.40.20.20.30.1-0.3-0.3-0.2-0.10.80.5-0.40.70.20.10.70.9
Sr content in liver0.20.21.00.3-0.9-0.20.2-0.2-0.70.1-0.20.40.50.2-0.3-0.4-0.50.4-0.40.7-0.40.11.00.2-0.30.40.2
Zn content in liver1.01.12.41.1-1.1-1.01.0-1.0-0.81.1-1.41.00.91.2-0.8-1.2-1.00.7-0.91.5-1.01.11.30.90.31.10.8
Bone: minimum diameter1.83.24.72.0-1.8-2.11.8-2.0-2.12.0-2.21.92.02.1-1.8-2.0-1.91.7-1.82.1-1.00.91.91.6-1.31.40.3
Time in familiar zone, hab. session 10.90.83.40.10.1-0.0-0.5-0.0-0.2-0.20.20.60.70.0-0.1-1.0-1.00.1-0.81.41.1-1.41.71.2-0.41.91.8
Time in novel zone, hab. session 11.71.77.2-0.20.10.10.70.10.20.00.0-1.0-1.1-0.30.21.51.5-0.21.2-2.1-1.61.8-2.3-1.70.5-2.7-2.4
Total zone transitions, hab. session 11.31.93.01.5-1.7-1.51.5-1.4-1.51.5-1.01.61.51.5-1.6-1.4-1.51.6-1.60.9-0.91.01.01.6-1.50.7-0.5
Total locomotion distance, hab. session 12.63.65.62.2-1.9-2.22.3-2.0-2.12.1-1.52.12.02.0-2.3-1.7-1.92.3-2.10.8-1.51.80.92.4-2.20.6-1.2
Locomotion velocity, hab. session 12.02.84.91.9-1.8-1.92.0-1.7-1.81.8-1.21.81.81.8-2.1-1.5-1.72.1-1.90.7-1.21.50.72.2-2.20.5-1.2
Time in familiar zone, hab. session 21.61.64.90.9-0.8-0.80.1-0.9-0.81.0-1.01.31.31.2-0.8-1.7-1.50.7-1.42.20.7-0.82.21.5-0.72.21.6
Time in novel zone, hab. session 21.11.13.4-0.80.80.7-0.30.80.7-0.91.1-1.0-1.1-1.10.61.41.2-0.61.1-1.8-0.20.2-1.8-1.10.3-1.7-1.3
Total zone transitions, hab. session 20.60.71.90.9-1.3-1.01.2-0.8-1.01.0-0.50.70.70.9-1.0-0.4-0.61.0-0.7-0.0-0.81.0-0.20.6-1.0-0.5-1.4
Total locomotion distance, hab. session 20.81.01.71.1-1.1-1.11.3-1.0-1.11.1-0.71.00.91.0-1.2-0.7-0.81.2-1.00.3-1.01.20.21.1-1.2-0.1-1.1
Locomotion velocity, hab. session 21.11.52.61.4-1.5-1.41.6-1.2-1.41.4-1.01.21.11.3-1.5-0.9-1.01.5-1.20.4-1.31.50.31.3-1.40.0-1.2
Novel to familiar place preference ratio1.41.63.3-1.21.81.3-1.41.31.5-0.91.8-1.2-1.2-0.90.91.21.2-1.01.0-1.61.8-1.4-1.6-0.8-0.0-0.8-0.5
Novelty place preference1.41.53.9-1.21.81.3-1.41.31.5-0.91.7-1.1-1.1-0.91.01.11.0-1.00.9-1.42.0-1.6-1.4-0.8-0.0-0.6-0.2
Time in novel zone, NPP test1.61.74.9-1.31.91.4-1.61.31.6-1.01.9-1.2-1.2-0.91.01.11.0-1.00.9-1.42.2-1.9-1.4-0.7-0.1-0.5-0.1
Total zone transitions, NPP test1.31.93.61.6-1.9-1.71.7-1.6-1.51.5-1.71.51.41.4-1.4-1.3-1.31.4-1.31.0-1.61.51.01.1-0.80.6-0.3
Total locomotion distance, NPP test1.01.42.11.4-1.4-1.41.4-1.3-1.31.1-1.31.31.21.1-1.4-1.1-1.21.4-1.20.6-1.41.20.71.3-1.00.4-0.6
Locomotion velocity, NPP test1.31.83.51.5-1.7-1.61.8-1.5-1.51.2-1.61.31.31.2-1.5-1.1-1.21.5-1.20.6-1.91.70.71.2-0.90.2-0.7
Intraocular pressure1.72.54.0-1.81.21.8-1.41.81.8-1.21.4-1.8-1.8-1.41.71.91.8-1.61.7-1.70.9-0.5-2.0-1.81.5-1.3-0.3
Delta distance traveled before/after self-admin0.20.20.3-0.40.60.6-0.50.50.5-0.10.1-0.5-0.5-0.10.50.30.4-0.50.4-0.20.4-0.4-0.3-0.00.50.10.3
Delta ambulatory time before/after self-admin0.20.20.5-0.50.60.6-0.60.60.6-0.10.1-0.5-0.50.00.50.30.3-0.50.4-0.20.7-0.5-0.20.10.20.20.4
Parametrial fat weight6.515.421.24.2-4.2-4.13.5-4.3-4.04.0-3.64.64.54.0-4.1-4.6-4.64.1-4.64.3-1.91.74.34.6-3.33.40.5
Pavlov. Cond. lever latency1.01.23.3-1.31.31.3-1.41.21.2-1.21.5-1.0-1.0-1.11.11.00.8-1.00.8-0.71.8-1.6-0.7-0.90.3-0.20.3
Pavlov. Cond. magazine entry latency1.01.34.21.3-1.3-1.31.5-1.3-1.51.0-0.90.80.80.8-1.3-0.5-0.61.3-0.70.2-2.01.80.00.5-0.6-0.8-1.7
Pavlov. Cond. change in total contacts0.50.64.00.6-0.7-0.60.9-0.5-0.70.5-1.00.0-0.00.3-0.20.00.20.20.2-0.1-2.01.9-0.1-0.50.9-0.7-0.5
Pavlov. Cond. index score0.60.83.21.1-1.1-1.11.1-1.0-1.20.8-1.10.70.70.7-0.9-0.6-0.60.9-0.50.4-1.81.50.50.50.0-0.2-0.6
Pavlov. Cond. latency score1.11.43.91.4-1.4-1.51.5-1.4-1.51.2-1.41.01.11.0-1.2-1.0-0.91.2-0.90.7-2.01.70.70.9-0.30.0-0.6
Pavlov. Cond. lever contacts1.21.44.31.4-1.4-1.51.6-1.4-1.41.3-1.61.01.01.1-1.2-0.9-0.81.1-0.80.6-2.11.90.60.7-0.2-0.0-0.6
Pavlov. Cond. magazine entry number0.40.52.3-0.60.60.7-0.70.60.8-0.40.3-0.2-0.3-0.20.70.10.1-0.70.10.31.5-1.30.3-0.0-0.10.91.3
Pavlov. Cond. intertrial magazine entries0.50.53.2-0.60.80.5-1.00.60.6-0.50.6-0.2-0.1-0.30.5-0.1-0.0-0.60.10.51.8-1.70.40.20.10.91.1
Pavlov. Cond. lever-magazine prob. diff.0.60.82.91.0-1.1-1.01.1-0.9-1.20.8-1.00.70.70.7-0.9-0.7-0.60.9-0.60.5-1.71.50.50.6-0.1-0.1-0.6
Pavlov. Cond. response bias0.40.43.00.6-0.6-0.60.8-0.5-0.70.4-0.60.10.20.3-0.5-0.00.00.50.0-0.2-1.71.5-0.2-0.10.3-0.8-1.0
Pavlov. Cond. lever latency0.91.22.3-1.11.30.9-0.80.91.2-1.10.9-1.2-1.2-1.21.01.41.3-0.91.2-1.50.1-0.1-1.5-1.40.8-1.3-0.7
Pavlov. Cond. magazine entry latency1.21.52.5-1.31.11.2-1.31.21.0-1.51.5-1.4-1.3-1.61.21.41.3-1.21.3-1.30.6-1.0-1.1-1.30.6-1.1-0.3
Pavlov. Cond. change in total contacts0.20.20.90.2-0.2-0.1-0.2-0.2-0.30.30.40.40.50.3-0.3-0.5-0.60.3-0.50.51.0-0.90.50.6-0.70.70.4
Pavlov. Cond. index score0.10.10.8-0.1-0.10.2-0.40.1-0.1-0.20.40.00.1-0.20.1-0.2-0.2-0.1-0.10.30.6-0.90.40.3-0.30.40.4
Pavlov. Cond. latency score0.10.10.40.1-0.2-0.0-0.1-0.1-0.3-0.10.30.20.3-0.1-0.1-0.3-0.30.1-0.20.40.3-0.60.40.3-0.40.30.3
Pavlov. Cond. lever contacts0.91.32.01.1-1.4-1.01.0-1.0-1.31.2-0.91.31.31.2-1.1-1.3-1.31.0-1.31.4-0.30.31.41.4-0.91.20.4
Pavlov. Cond. magazine entry number1.82.23.31.7-1.4-1.81.8-1.8-1.51.8-1.71.51.51.7-1.8-1.3-1.41.7-1.50.8-1.51.80.61.3-1.00.3-0.9
Pavlov. Cond. intertrial magazine entries2.94.46.52.4-2.3-2.42.5-2.4-2.52.5-2.12.22.12.3-2.4-1.9-1.92.3-2.11.2-2.32.51.31.9-1.10.6-1.0
Pavlov. Cond. lever-magazine prob. diff.0.10.10.9-0.30.20.4-0.60.30.1-0.40.7-0.2-0.2-0.40.30.10.1-0.30.2-0.00.7-0.9-0.0-0.0-0.10.10.2
Pavlov. Cond. response bias0.20.31.2-0.3-0.00.5-0.60.40.1-0.20.3-0.0-0.0-0.10.4-0.2-0.1-0.4-0.00.60.9-1.00.60.20.10.91.1
Time in closed arm before self-admin0.50.62.4-0.90.80.7-1.20.80.8-1.00.9-0.6-0.5-0.90.80.50.4-0.70.5-0.21.2-1.6-0.2-0.1-0.10.10.6
Time in closed arm after self-admin3.53.76.5-2.11.92.0-1.82.21.9-2.51.7-2.1-2.1-2.52.41.92.0-2.42.2-1.20.7-1.2-1.3-1.62.3-0.81.2
Time in open arm before self-admin0.40.41.60.0-0.1-0.10.6-0.1-0.10.1-0.3-0.3-0.5-0.20.10.60.6-0.20.5-0.8-1.21.3-0.8-1.00.9-1.1-0.9
Time in open arm after self-admin4.34.78.32.4-2.2-2.32.0-2.4-2.22.7-2.02.52.42.9-2.6-2.3-2.42.5-2.51.8-0.81.41.81.9-2.21.3-0.7
Bone: periosteal estimation4.08.513.73.2-3.1-3.22.9-3.2-3.33.3-3.73.23.23.4-2.8-3.3-3.12.7-3.03.4-1.61.63.32.5-1.92.40.8
Bone: periosteal perimeter1.73.04.82.1-2.0-2.02.1-2.1-2.11.9-2.21.81.81.8-1.8-1.7-1.61.7-1.61.4-1.81.61.41.0-1.20.5-0.5
Bone: post-yield work4.97.211.63.1-3.2-3.03.1-2.9-3.42.9-3.02.92.82.9-2.8-2.8-2.72.8-2.72.5-2.22.02.72.3-2.21.5-0.4
Progressive ratio test 1 active lever presses0.10.10.9-0.2-0.00.0-0.30.4-0.0-0.10.9-0.1-0.10.1-0.00.20.10.00.0-0.30.20.0-0.30.30.4-0.2-0.5
Progressive ratio test 1 breakpoint0.10.11.2-0.30.00.1-0.40.50.0-0.21.1-0.2-0.20.0-0.00.20.10.00.0-0.40.3-0.1-0.40.30.3-0.2-0.5
Progressive ratio test 1 inactive lever presses0.10.10.80.0-0.2-0.0-0.10.1-0.10.10.3-0.0-0.00.3-0.10.00.00.1-0.0-0.2-0.50.4-0.20.90.3-0.1-0.3
Progressive ratio test 2 active lever presses1.41.72.9-1.51.11.2-1.51.71.2-1.31.7-1.5-1.4-1.21.41.41.4-1.41.4-1.11.0-1.0-1.1-1.01.4-0.80.1
Progressive ratio test 2 breakpoint1.21.42.6-1.41.01.1-1.41.51.0-1.21.6-1.3-1.3-1.11.21.31.2-1.31.3-1.10.8-0.9-1.0-0.91.3-0.8-0.0
Progressive ratio test 2 inactive lever presses0.20.30.9-0.30.20.2-0.10.30.2-0.20.2-0.6-0.6-0.20.40.70.7-0.40.7-0.8-0.50.3-0.8-0.60.7-1.0-0.5
Incentive Sensitization - Responses0.81.11.7-1.10.90.9-1.01.20.9-0.81.0-1.3-1.2-0.91.11.31.3-1.11.3-1.30.4-0.5-1.3-1.10.9-1.2-0.5
Incentive Sensitization - Breakpoint0.50.71.2-0.80.60.7-0.80.90.7-0.60.7-1.0-1.0-0.70.81.01.1-0.81.1-1.10.2-0.3-1.1-0.90.7-1.1-0.5
Sum of active levers in priming session hrs 5-61.21.14.61.2-1.2-1.11.5-1.1-1.21.1-0.90.60.50.9-1.0-0.4-0.30.9-0.4-0.2-2.12.1-0.20.4-0.3-0.9-1.3
Progressive ratio0.30.52.50.5-0.6-0.50.8-0.5-0.60.20.00.20.2-0.1-0.60.20.00.6-0.1-0.7-1.31.3-0.70.1-0.5-1.2-1.6
Food seeking constrained by brief footshock0.10.10.7-0.0-0.1-0.1-0.0-0.00.0-0.10.7-0.00.0-0.1-0.20.20.00.2-0.1-0.50.4-0.3-0.5-0.1-0.7-0.5-0.8
Seeking ratio, punishment vs. effort0.00.00.20.1-0.0-0.20.1-0.10.00.4-0.20.20.10.4-0.1-0.3-0.20.1-0.20.30.2-0.10.3-0.00.00.40.3
Retroperitoneal fat weight1.46.110.32.7-3.0-2.72.6-2.8-3.02.2-1.52.82.81.9-3.1-2.2-2.63.2-2.91.6-2.01.71.52.9-3.10.4-1.9
Reaction time number correct1.22.43.3-1.71.31.7-1.51.81.6-1.71.6-1.8-1.8-1.71.71.71.7-1.71.8-1.51.1-1.1-1.6-1.61.0-1.10.0
Reaction time mean minus median0.10.10.40.4-0.4-0.40.3-0.3-0.50.3-0.10.40.40.3-0.5-0.3-0.40.5-0.40.2-0.1-0.00.30.6-0.60.1-0.4
Reaction time mean minus median AUC0.00.10.2-0.40.20.4-0.30.40.3-0.30.5-0.4-0.3-0.30.30.40.3-0.20.3-0.50.5-0.5-0.3-0.3-0.2-0.3-0.3
Reaction time num false alarms0.20.21.2-0.50.80.4-0.60.50.8-0.30.4-0.3-0.3-0.20.40.20.2-0.40.2-0.11.1-0.9-0.3-0.2-0.00.30.5
Reaction time num false alarms AUC0.00.00.1-0.10.2-0.00.00.00.30.0-0.1-0.0-0.10.00.10.00.0-0.10.00.10.2-0.0-0.2-0.1-0.00.10.2
Reaction time trials correct on left1.22.43.3-1.71.31.7-1.51.81.6-1.71.6-1.8-1.8-1.71.71.71.7-1.71.8-1.51.1-1.1-1.6-1.61.0-1.10.0
Reaction time trials on left1.22.33.2-1.71.31.7-1.51.81.6-1.71.6-1.8-1.8-1.71.71.71.7-1.71.7-1.51.0-1.1-1.6-1.61.0-1.10.0
Reaction time mean0.30.53.90.4-0.3-0.40.7-0.3-0.50.30.30.10.10.1-0.70.30.10.7-0.1-1.1-1.01.1-1.00.1-0.7-1.3-2.0
Reaction time mean AUC0.40.63.80.2-0.1-0.20.6-0.2-0.30.10.4-0.2-0.2-0.1-0.40.60.40.40.2-1.3-1.11.2-1.2-0.3-0.4-1.6-2.0
Median of all reaction times0.50.74.70.3-0.2-0.40.7-0.3-0.40.30.3-0.0-0.10.1-0.60.50.30.70.0-1.3-1.21.3-1.3-0.1-0.6-1.5-2.2
Reaction time omissions0.40.62.8-0.0-0.40.10.5-0.0-0.0-0.1-0.1-0.4-0.5-0.40.10.70.7-0.00.6-1.1-1.71.5-1.1-1.20.3-1.4-1.3
Reaction time false alarm rate0.20.30.50.5-0.1-0.60.4-0.6-0.20.7-0.70.70.60.7-0.5-0.7-0.70.5-0.60.70.00.20.50.5-0.40.70.4
Reaction time premature initiation rate0.81.13.1-0.40.10.50.50.40.2-0.3-0.1-0.9-1.0-0.60.51.21.2-0.51.1-1.6-1.61.7-1.5-1.71.0-1.8-1.3
Reaction time premature initiations1.62.97.0-1.30.81.3-0.21.41.1-1.20.6-1.9-2.0-1.61.42.12.2-1.42.1-2.4-1.31.3-2.4-2.61.7-2.4-1.2
Std. dev. reaction times0.10.21.20.5-0.4-0.50.5-0.4-0.70.20.00.30.30.1-0.6-0.1-0.20.6-0.3-0.3-0.70.6-0.20.3-0.6-0.6-1.1
Reaction time trials completed1.22.33.2-1.71.31.7-1.51.81.6-1.71.6-1.8-1.8-1.71.71.71.7-1.71.7-1.51.0-1.1-1.6-1.61.0-1.10.0
Reaction time trials AUC1.01.92.6-1.51.21.5-1.31.61.5-1.51.4-1.6-1.6-1.51.51.61.6-1.51.6-1.40.9-1.0-1.4-1.40.9-1.0-0.0
Run reversals in cocaine runway, females1.51.56.21.3-1.4-1.31.8-1.2-1.31.3-1.51.00.91.1-1.2-0.7-0.71.2-0.80.4-2.42.50.40.3-0.0-0.3-1.0
Run reversals in cocaine runway, males0.20.21.1-0.30.50.3-0.00.40.3-0.1-0.3-0.4-0.5-0.10.50.30.4-0.50.5-0.0-0.30.3-0.00.21.1-0.00.5
Latency to leave start box in cocaine runway1.21.43.61.0-0.9-0.70.8-0.9-1.00.7-0.61.41.40.9-0.9-1.5-1.50.9-1.51.80.2-0.11.91.2-1.01.81.1
Latency to leave start box in cocaine runway, F0.30.42.0-0.40.00.5-0.60.50.3-0.70.60.00.0-0.60.5-0.2-0.2-0.4-0.10.80.8-1.00.8-0.20.31.01.4
Latency to leave start box in cocaine runway, M2.82.74.11.8-1.3-1.51.8-1.7-1.71.6-1.51.91.81.7-1.8-1.8-1.91.7-1.91.7-0.71.01.72.0-1.81.40.1
Std. dev. time between licks in bursts0.10.21.2-0.3-0.10.2-0.50.4-0.2-0.31.1-0.2-0.1-0.0-0.10.30.10.1-0.0-0.40.7-0.6-0.40.6-0.5-0.4-0.8
Total sessions with >9 infusions0.30.41.10.6-0.9-0.80.5-0.3-0.90.50.30.40.50.7-0.7-0.4-0.40.7-0.50.1-0.81.00.11.0-0.0-0.1-0.9
Short access day 1 total inactive lever presses0.50.62.70.0-0.2-0.20.60.0-0.2-0.1-0.1-0.5-0.6-0.20.10.70.8-0.10.7-1.1-1.61.5-1.1-0.10.4-1.6-1.3
Short access day 10 total inactive lever presses0.30.71.4-1.01.01.1-1.01.01.0-0.90.6-1.0-1.0-0.71.10.80.9-1.11.0-0.50.4-0.5-0.5-0.41.2-0.00.8
Short access day 1 total infusions1.82.35.4-1.40.91.0-0.91.60.9-1.31.8-1.8-1.8-1.41.22.01.9-1.21.8-2.3-0.30.4-2.3-1.41.3-2.2-1.5
Short access day 10 total infusions0.10.10.7-0.3-0.10.1-0.50.5-0.0-0.40.8-0.3-0.2-0.10.10.10.1-0.20.2-0.20.00.0-0.20.40.6-0.0-0.1
Short access total infusions0.10.20.9-0.0-0.5-0.30.10.3-0.4-0.10.8-0.2-0.10.0-0.20.20.20.20.1-0.5-0.60.7-0.40.20.4-0.6-1.0
Short access day 1 locomotion1.51.94.4-1.51.21.3-1.31.81.3-1.41.4-1.6-1.7-1.11.61.51.6-1.71.6-1.20.3-0.3-1.2-1.02.1-0.70.4
Short access day 10 total locomotion0.40.72.30.6-0.3-0.4-0.1-0.6-0.30.7-0.60.80.91.0-0.6-1.1-1.00.6-0.91.30.6-0.61.31.5-0.61.51.0
Short access total locomotion0.60.72.40.8-0.9-0.80.4-0.5-0.90.7-0.10.90.91.1-0.8-1.0-1.00.8-1.01.0-0.10.11.01.6-0.30.90.2
One hour access (0.3 mA shock)0.20.20.80.3-0.2-0.2-0.4-0.5-0.20.30.30.50.60.3-0.6-0.4-0.60.7-0.70.20.7-0.60.20.4-0.90.1-0.6
Compulsive drug intake0.91.11.81.3-1.0-1.21.4-1.2-1.11.0-0.91.11.01.0-1.2-0.9-0.91.2-1.00.5-1.11.30.51.1-1.00.1-0.7
One hour access (shock baseline)0.10.21.6-0.40.30.5-0.90.20.4-0.20.4-0.10.0-0.10.20.0-0.1-0.1-0.10.11.3-1.20.1-0.2-0.20.30.2
Social response proportion0.70.81.6-1.01.00.9-0.90.90.8-1.01.2-0.9-0.8-1.00.61.10.9-0.50.8-1.30.5-0.4-1.3-0.50.6-1.0-0.8
Social responses0.40.51.1-0.70.80.5-0.70.60.3-0.91.0-0.7-0.5-0.90.40.80.6-0.30.6-0.90.4-0.6-0.8-0.70.3-1.0-0.8
Social time0.81.13.1-1.11.10.9-1.10.91.0-1.11.8-1.0-0.9-1.10.61.20.9-0.50.7-1.41.0-0.9-1.3-0.8-0.2-1.2-1.2
Soleus weight4.011.717.93.9-3.8-4.23.4-3.9-3.63.7-3.63.83.93.7-3.7-3.8-3.83.6-3.73.3-2.42.33.13.3-2.52.40.0
Bone: stiffness6.310.315.63.5-3.1-3.43.2-3.5-3.33.7-3.93.63.53.8-3.1-3.8-3.62.9-3.43.6-1.41.73.73.1-2.13.01.1
Tibialis anterior weight7.224.537.65.7-6.1-5.75.7-5.5-5.75.7-5.25.25.25.7-5.5-4.8-4.85.4-5.03.6-4.54.73.54.4-4.32.0-1.7
Time to tail flick, vehicle, before self-admin0.90.91.61.1-1.1-1.01.2-1.3-1.11.1-1.01.11.01.0-1.1-0.8-0.91.2-1.00.6-1.10.80.60.6-0.80.0-0.7
Time to tail flick, vehicle, after self-admin0.00.00.20.1-0.1-0.20.1-0.2-0.10.1-0.10.00.0-0.1-0.00.00.10.00.0-0.1-0.1-0.2-0.10.50.0-0.3-0.2
Time to tail flick, test, before self-admin1.61.62.51.5-1.6-1.51.5-1.5-1.61.4-1.11.21.31.2-1.5-1.1-1.11.5-1.10.6-1.41.10.71.5-1.10.1-0.9
Time to tail flick, test, after self-admin0.50.52.1-0.30.30.2-0.90.40.3-0.90.60.10.2-0.60.3-0.4-0.4-0.3-0.20.90.9-1.40.90.60.11.21.4
Delta time to tail flick, vehicle, before/after SA0.10.10.50.1-0.1-0.20.00.0-0.10.2-0.20.20.20.2-0.0-0.3-0.2-0.1-0.20.50.1-0.10.50.70.20.60.6
Delta time to tail flick, test, before/after SA0.40.41.8-0.60.50.4-0.90.60.5-0.90.8-0.1-0.0-0.60.5-0.1-0.2-0.4-0.00.51.2-1.40.50.1-0.10.91.1
Tibia length0.10.30.80.5-0.5-0.40.4-0.6-0.70.7-0.50.60.60.7-0.6-0.6-0.50.5-0.60.90.00.10.70.7-0.90.3-0.1
Ambulatory time before self-admin0.91.42.9-1.31.31.4-1.11.51.3-1.11.1-1.3-1.3-1.01.41.11.2-1.51.3-0.80.5-0.1-0.8-1.31.7-0.30.7
Ambulatory time after self-admin1.72.04.1-1.61.61.7-1.41.71.6-0.81.0-1.7-1.8-0.81.61.51.7-1.61.7-1.40.40.2-1.5-1.42.0-0.80.2
Bone: tissue strength0.20.21.60.4-0.3-0.40.8-0.3-0.30.5-0.50.1-0.00.4-0.30.00.10.2-0.0-0.4-0.91.3-0.40.3-0.0-0.4-0.6
Total heroin consumption0.30.42.80.4-0.4-0.40.3-0.6-0.40.70.10.10.20.5-0.60.20.10.6-0.2-0.7-0.1-0.0-0.7-0.3-0.9-1.1-1.7
Bone: trabecular number0.30.51.30.7-0.8-0.80.5-0.6-0.50.8-0.60.80.90.8-0.7-0.8-0.90.7-0.90.60.1-0.10.51.1-0.90.70.1
Bone: trabecular spacing0.70.92.8-0.50.60.5-0.00.40.6-0.70.3-0.9-1.0-0.90.51.21.2-0.51.1-1.4-1.01.0-1.5-1.30.5-1.7-1.2
Bone: trabecular thickness1.82.23.61.5-1.3-1.60.9-1.5-1.51.5-1.01.71.91.6-1.6-1.8-1.91.6-1.91.70.5-0.41.61.8-1.61.50.2
Bone: trabecular tissue density0.81.22.51.4-1.0-1.61.5-1.6-1.41.2-1.41.11.01.0-1.2-0.8-0.81.2-0.90.4-1.21.20.50.5-0.7-0.2-0.8
Water consumed over 24 hours1.21.63.2-1.51.11.4-1.31.51.3-1.40.2-1.5-1.5-1.21.81.21.4-1.81.6-0.40.6-0.9-0.5-1.31.7-0.31.2
Number of responses in last shaping day0.70.82.7-0.50.20.3-0.20.50.3-0.50.9-0.8-0.9-0.50.31.11.0-0.30.8-1.6-0.90.8-1.6-0.30.6-1.6-1.6