Hub : Genes

Gstp3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver isoform ratio NM_001398780.1 0.34 0.16 4.7e-09 0.06 0.08 0.08 0.06 4.7e-07 2.7e-09 5.1e-09 5.1e-07
2 Liver isoform ratio XM_039108270.1 0.65 0.13 0.0e+00 0.4 0.41 0.43 0.4 5.4e-47 8.8e-49 5.8e-52 1.2e-47
3 Liver isoform ratio XM_039108277.1 0.77 0.14 0.0e+00 0.42 0.44 0.46 0.44 6.9e-50 5.4e-54 6.8e-56 9.3e-53
4 Liver alternative TSS XM_039108277.1 0.1 0.07 4.5e-07 0.04 0.04 0.05 0.04 6.0e-05 6.9e-05 6.6e-06 2.4e-05
5 Liver alternative TSS NM_001134508.2 0.1 0.07 3.6e-07 0.04 0.04 0.04 0.04 6.5e-05 4.7e-05 7.6e-05 1.5e-05
6 Liver alternative TSS NM_001134508.2 0.06 0.06 2.4e-03 0.02 0.01 0.01 0.01 2.8e-03 3.9e-02 2.2e-02 1.3e-02
7 Liver alternative TSS XM_017589017.1 0.09 0.09 8.6e-04 0.02 0.01 0.01 0.02 4.4e-03 1.3e-02 7.3e-03 5.7e-03
8 Liver gene expression Gstp3 0.04 0.03 1.1e-03 0.01 0.02 0.02 0.01 1.6e-02 1.7e-03 3.6e-03 9.9e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bone: apparent density0.91.45.9-0.70.1-0.7-0.40.9-1.31.4-2.4
Area under the delay curve0.40.51.50.1-0.2-0.10.00.6-1.00.8-1.2
BMI with tail1.44.48.6-2.82.4-2.9-2.5-0.7-0.40.3-2.5
BMI without tail0.71.53.2-1.81.2-1.7-1.3-0.4-0.10.2-1.5
Body weight2.510.318.0-4.23.9-4.1-3.9-2.92.2-2.2-0.4
Weight adjusted by age1.61.82.9-1.61.7-1.6-1.4-1.51.1-1.20.1
Bone surface1.42.55.1-2.21.6-2.1-1.7-0.4-0.40.3-2.2
Bone volume0.71.14.5-1.00.5-1.0-0.70.5-1.01.0-2.1
Breakpoint value in progressive ratio session1.82.03.2-1.81.6-1.7-1.6-1.41.0-1.1-0.1
Number of licking bursts0.00.00.1-0.10.1-0.20.0-0.0-0.10.1-0.4
Context. condit. distance diff. score0.80.91.31.1-1.01.00.91.1-1.00.9-0.5
Locomotion velocity, session 10.00.00.0-0.00.1-0.1-0.2-0.00.0-0.0-0.1
Locomotion distance, session 10.60.82.5-0.80.7-1.0-0.80.1-0.60.6-1.6
Locomotion velocity, session 22.12.53.7-1.91.9-1.9-1.9-1.61.3-1.30.2
Locomotion distance, session 20.70.91.9-1.31.2-1.4-1.3-0.60.2-0.2-0.8
Locomotion velocity, session 30.60.72.5-0.1-0.1-0.2-0.10.9-1.21.1-1.6
Locomotion distance, session 30.10.10.2-0.00.2-0.1-0.30.2-0.30.3-0.4
Stereotopy head waving bouts, day 31.01.22.30.5-0.90.50.81.2-1.41.3-1.5
Stereotopy head waving duration, day 31.41.72.21.1-1.41.11.41.4-1.51.3-1.1
Locomotion velocity, session 70.50.51.7-0.00.0-0.2-0.10.7-1.01.1-1.3
Locomotion distance, session 70.20.20.5-0.70.6-0.7-0.6-0.30.10.0-0.4
Stereotopy head waving bouts, day 71.31.52.50.8-1.00.80.91.4-1.61.5-1.4
Stereotopy head waving duration, day 70.60.72.5-0.80.5-0.8-0.50.4-0.80.7-1.6
Locomotion velocity, session 81.31.52.2-1.51.5-1.5-1.5-1.21.0-1.00.0
Locomotion distance, session 80.20.30.60.4-0.30.20.20.6-0.70.7-0.8
Degree of sensitization distance0.20.20.4-0.60.4-0.6-0.3-0.1-0.10.2-0.6
Degree of sensitization stereotypy0.20.20.9-0.40.2-0.4-0.20.3-0.50.4-1.0
Conditioned locomotion3.44.05.9-1.61.9-1.5-1.7-2.42.4-2.41.8
Cocaine response after cond. corrected0.20.20.30.4-0.50.40.60.4-0.40.4-0.3
Cocaine response after cond. not corrected0.40.40.70.4-0.50.40.50.7-0.80.8-0.7
Cocaine response before conditioning0.10.10.2-0.30.3-0.3-0.40.2-0.30.3-0.5
Saline control response2.12.84.6-2.11.9-2.0-1.8-1.71.3-1.3-0.0
Bone: connectivity density1.42.25.4-2.01.3-1.9-1.6-0.2-0.50.5-2.3
Bone: cortical apparent density0.60.81.0-0.91.0-0.9-0.9-1.00.9-0.90.5
Bone: cortical area0.61.01.7-0.80.8-0.7-0.6-1.21.3-1.31.0
Bone: cortical porosity0.00.00.10.00.1-0.1-0.10.2-0.20.2-0.3
Bone: cortical porosity0.30.30.6-0.60.8-0.7-0.7-0.40.4-0.4-0.0
Bone: cortical thickness4.98.111.4-2.62.7-2.4-2.4-3.43.4-3.42.2
Bone: cortical thickness2.12.53.4-1.71.5-1.4-1.4-1.91.8-1.81.0
Bone: cortical tissue density0.71.01.2-1.01.1-1.0-1.0-1.11.0-1.00.5
Condit. Reinf. active minus inactive responses0.20.20.6-0.20.3-0.4-0.30.2-0.50.5-0.8
Condit. Reinf. active-inactive response ratio0.20.20.50.1-0.10.0-0.00.5-0.60.7-0.7
Condit. Reinf. active responses0.00.00.10.00.2-0.1-0.10.2-0.20.3-0.3
Condit. Reinf. inactive responses0.00.00.10.20.00.10.00.10.00.00.3
Incentive salience index mean0.20.20.4-0.40.5-0.6-0.5-0.0-0.20.2-0.6
Condit. Reinf. lever presses0.10.10.3-0.30.5-0.4-0.4-0.40.3-0.30.2
Condit. Reinf. active minus inactive responses1.51.83.20.9-1.00.80.91.6-1.71.8-1.5
Condit. Reinf. active-inactive response ratio2.42.53.31.6-1.61.51.61.8-1.71.7-1.0
Condit. Reinf. active responses0.91.33.20.2-0.40.10.31.3-1.61.6-1.8
Condit. Reinf. inactive responses0.60.71.3-1.10.9-1.1-1.0-0.1-0.30.2-1.1
Condit. Reinf. lever presses0.50.61.2-1.10.8-1.1-0.8-0.2-0.10.1-1.1
Condit. Reinf. lever reinforcers received0.71.03.3-0.1-0.2-0.20.01.1-1.41.4-1.8
Conditioned reinforcement - actives0.30.30.70.6-0.70.80.40.2-0.30.00.7
Conditioned reinforcement - inactives5.76.49.13.0-3.03.02.72.6-2.32.3-0.1
Conditioned locomotion5.87.013.33.7-3.13.63.12.2-1.61.41.1
Patch foraging indifference point 0 sec0.50.81.21.0-1.00.90.81.1-0.90.9-0.2
Patch foraging indifference point AUC2.12.53.4-1.41.7-1.6-1.8-1.71.5-1.70.8
Delay disc. indifference point, 0s delay0.90.92.70.1-0.5-0.00.11.0-1.41.3-1.6
Delay disc. indifference point, 16s delay1.41.41.91.4-1.31.21.21.2-1.31.1-0.6
Delay disc. indifference point, 2s delay0.40.50.80.5-0.60.30.60.7-0.90.8-0.9
Delay disc. indifference point, 24s delay0.10.10.4-0.1-0.10.0-0.2-0.50.3-0.60.6
Delay disc. indifference point, 4s delay0.20.20.6-0.20.4-0.5-0.50.1-0.40.2-0.8
Delay disc. indifference point, 8s delay0.10.10.6-0.10.0-0.2-0.00.3-0.50.4-0.7
Indifference point function ln k4.05.58.82.8-2.92.93.02.2-1.71.8-0.0
Indifference point function log k4.05.58.82.8-2.92.93.02.2-1.71.8-0.0
Patch foraging total patch changes 0 sec0.20.20.40.7-0.60.70.50.5-0.30.30.3
Patch foraging total patch changes 12 sec2.22.84.5-1.92.0-2.0-2.1-1.61.3-1.40.2
Patch foraging total patch changes 18 sec0.20.20.5-0.50.5-0.7-0.7-0.30.2-0.2-0.2
Patch foraging total patch changes 24 sec1.11.31.7-1.11.2-1.0-1.2-1.31.3-1.30.7
Patch foraging total patch changes 6 sec0.40.61.1-1.00.8-1.0-1.1-0.2-0.10.0-0.8
Patch foraging time to switch 0 sec1.11.74.1-1.51.3-1.7-1.3-0.1-0.50.6-2.0
Patch foraging water rate 0 sec2.54.07.82.7-2.32.82.30.80.1-0.22.3
Patch foraging water rate 12 sec3.55.310.63.2-2.73.32.81.1-0.10.12.4
Patch foraging water rate 18 sec1.01.32.61.5-1.41.51.60.7-0.40.30.7
Patch foraging water rate 24 sec1.52.13.71.8-1.61.91.80.30.3-0.31.9
Patch foraging water rate 6 sec0.91.43.41.4-1.01.51.3-0.10.7-0.71.8
Seeking ratio, delayed vs. immediate footshock0.20.31.1-0.2-0.1-0.20.20.3-0.70.6-1.1
Distance traveled before self-admin0.20.20.3-0.40.6-0.6-0.3-0.30.5-0.2-0.3
Distance traveled after self-admin0.10.10.3-0.1-0.20.20.50.20.00.2-0.2
Extensor digitorum longus weight6.023.732.5-5.65.7-5.6-5.4-5.24.3-4.41.2
Bone: elastic displacement1.01.24.50.4-0.20.50.3-0.91.3-1.32.1
Bone: elastic work2.22.84.4-1.41.5-1.3-1.3-2.02.1-2.11.6
Bone: endosteal estimation1.73.85.61.7-1.81.61.62.3-2.42.3-1.7
Bone: endosteal perimeter3.88.011.22.5-2.72.42.63.3-3.33.2-2.3
Epididymis fat weight2.96.610.13.2-2.92.93.02.6-2.22.2-0.4
Delta time in closed arm before/after self-admin1.31.31.9-1.01.1-1.0-1.4-1.31.1-1.30.8
Delta time in open arm before/after self-admin0.30.30.50.4-0.40.40.40.6-0.50.7-0.3
Diff in mean of infusions in LGA sessions0.60.61.0-0.80.6-0.7-0.6-1.01.0-1.00.4
Delay discount exponential model param0.30.31.1-0.00.00.20.1-0.40.8-0.61.0
Extinction: sum of active levers before priming2.52.55.4-2.31.6-1.9-1.8-1.60.8-1.1-0.6
Active lever presses in extinction session 62.42.33.0-1.21.7-1.3-1.6-1.61.7-1.71.3
Bone: final force1.11.83.4-1.81.5-1.7-1.4-1.31.0-1.0-0.4
Bone: final moment1.01.63.0-1.71.4-1.6-1.3-1.20.9-0.9-0.3
Food consumed during 24 hour testing period0.20.30.50.7-0.60.70.70.20.1-0.00.5
Glucose2.33.45.11.6-1.71.41.52.1-2.32.2-1.8
Heart weight1.72.33.21.7-1.71.61.81.6-1.51.4-0.5
Delay discount hyperbolic model param0.30.31.10.0-0.10.30.2-0.40.7-0.51.1
Intermittent access intake day 1-15 change1.21.12.31.4-1.31.51.50.6-0.40.20.6
Intermittent access intake escalation1.21.22.31.4-1.41.51.50.8-0.70.50.1
Intermittent access intake escalation 20.60.61.31.0-0.91.11.10.5-0.30.20.4
Intermitt. access day 1 inactive lever presses1.81.92.61.5-1.51.51.61.5-1.41.3-0.3
Intermitt. access day 15 inactive lever presses3.33.65.81.8-2.42.02.41.8-2.01.7-0.7
Intermitt. access escalation Index1.51.43.01.7-1.31.51.60.9-0.50.50.4
Intermittent access day 1 total infusions6.37.312.62.2-2.41.82.23.3-3.33.6-2.5
Intermittent access day 15 total infusions8.69.711.93.4-3.53.23.33.4-3.13.1-1.2
Intermittent access terminal intake (last 3 days)6.87.49.32.8-2.92.52.83.0-2.93.0-1.5
Intermittent access total infusions4.95.47.72.2-2.31.92.12.7-2.82.7-1.6
Intermittent access day 1 locomotion3.23.46.71.2-1.30.91.12.2-2.62.6-2.0
Intermittent access day 15 total locomotion4.34.66.12.5-2.32.22.22.3-2.22.2-0.9
Intermittent access total locomotion7.08.011.02.8-2.82.42.63.2-3.33.3-2.0
Intermittent access standard deviation0.70.81.31.1-1.11.21.00.7-0.70.50.0
Left kidney weight0.72.14.12.0-1.81.91.71.1-0.60.50.9
Right kidney weight0.51.42.81.7-1.31.61.40.60.0-0.01.4
Cocaine induced anxiety0.00.00.10.2-0.20.20.10.1-0.00.10.1
Post-drug Anxiety1.11.21.9-1.10.9-0.9-0.8-1.31.4-1.30.9
Baseline Anxiety2.22.32.9-1.71.6-1.5-1.3-1.71.7-1.70.8
Tail length0.92.84.8-1.61.2-1.0-1.2-2.02.2-2.11.7
Length with tail2.48.811.1-3.23.0-2.8-2.9-3.33.2-3.21.7
Length without tail2.35.06.8-2.52.6-2.5-2.5-2.42.1-2.10.7
Times rat made contact with spout0.30.40.7-0.80.6-0.8-0.7-0.2-0.00.0-0.8
Lifetime Intake4.24.77.12.0-2.11.71.82.5-2.62.7-1.6
Liver weight, left0.10.10.40.4-0.50.50.60.3-0.10.20.0
Liver weight, right0.10.20.60.3-0.20.40.2-0.20.4-0.40.8
Locomotor activity0.50.81.71.1-1.11.30.90.6-0.20.20.7
Locomotor testing distance0.61.02.11.3-1.31.51.20.7-0.30.30.7
Locomotor testing rearing0.81.21.51.1-1.11.11.11.2-1.21.1-0.7
Locomotion in novel chamber5.97.310.23.2-3.13.03.12.8-2.42.5-0.8
Locomotion in novel chamber post-restriction2.93.55.82.2-2.42.22.21.8-1.41.4-0.0
Fecal boli incidents, locomotor time 10.10.10.30.1-0.20.20.50.2-0.20.2-0.1
Change in fecal boli incidents, locomotor task0.10.10.3-0.50.3-0.5-0.6-0.1-0.10.1-0.4
Time >=10cm from walls, locomotor time 13.63.76.81.3-1.81.31.22.2-2.62.4-2.0
Bouts of movement, locomotor time 11.41.52.3-1.01.1-1.0-1.4-1.41.5-1.51.0
Total resting periods, locomotor time 10.90.91.6-0.60.8-0.6-1.0-1.11.2-1.20.9
Rest time, locomotor task time 10.91.02.01.4-1.11.41.00.60.10.11.0
Distance moved, locomotor task time 10.40.41.6-0.20.1-0.40.30.5-0.80.9-1.3
Vertical activity count, locomotor time 11.71.82.71.2-1.51.21.61.4-1.41.5-0.8
Time >=10cm from walls, locomotor time 20.10.10.30.4-0.50.60.40.1-0.3-0.00.3
Bouts of movement, locomotor time 20.40.40.6-0.80.7-0.7-0.7-0.80.4-0.70.3
Total resting periods, locomotor time 20.10.10.2-0.40.4-0.4-0.5-0.40.1-0.30.1
Rest time, locomotor task time 22.52.84.11.8-1.81.51.42.0-1.71.9-1.0
Distance moved, locomotor task time 21.11.32.1-1.11.3-1.0-0.6-1.31.4-1.30.8
Vertical activity count, locomotor time 21.11.23.4-0.40.40.00.1-1.21.5-1.51.8
Light reinforcement 10.30.61.61.3-0.91.10.80.4-0.20.00.5
Light reinforcement 21.62.14.62.2-1.71.91.61.3-0.80.80.5
Bone: marrow area1.83.95.71.7-1.81.61.72.3-2.42.3-1.7
Bone: maximum diameter0.10.10.20.5-0.40.50.50.2-0.00.00.3
Bone: maximum force1.01.73.2-1.81.3-1.8-1.3-0.4-0.20.1-1.8
Bone: maximum moment0.81.42.8-1.71.3-1.7-1.2-0.4-0.10.1-1.6
Mean time between licks in bursts0.60.91.4-1.21.0-1.0-0.9-1.00.9-0.90.3
Mean num. licks in bursts0.00.00.1-0.20.0-0.1-0.20.2-0.20.2-0.3
Cd content in liver1.11.22.21.5-1.31.41.41.0-0.60.70.4
Co content in liver0.30.41.50.5-0.20.50.0-0.30.6-0.61.2
Cu content in liver0.10.20.3-0.40.5-0.4-0.5-0.40.4-0.40.3
Fe content in liver0.10.10.2-0.30.3-0.3-0.5-0.30.2-0.30.0
K content in liver1.01.01.9-1.31.2-1.4-1.3-0.3-0.20.1-1.3
Mg content in liver1.31.44.5-0.0-0.1-0.20.01.2-1.61.6-2.1
Mn content in liver1.01.21.9-1.41.3-1.4-1.4-1.00.7-0.7-0.1
Na content in liver0.30.30.7-0.20.3-0.1-0.4-0.70.8-0.80.7
Rb content in liver2.73.45.81.3-1.51.11.32.3-2.42.4-1.9
Se content in liver0.50.61.20.4-0.40.30.40.9-1.01.0-1.1
Sr content in liver2.82.53.5-1.51.6-1.4-1.5-1.91.8-1.81.1
Zn content in liver0.70.81.2-1.11.0-1.0-1.0-1.00.8-0.80.3
Bone: minimum diameter1.83.35.51.2-1.51.11.32.2-2.32.3-2.1
Time in familiar zone, hab. session 10.60.61.00.7-0.70.60.50.9-0.91.0-0.6
Time in novel zone, hab. session 10.10.10.1-0.20.2-0.2-0.1-0.30.3-0.40.3
Total zone transitions, hab. session 10.30.50.9-0.90.9-0.9-0.9-0.50.2-0.2-0.4
Total locomotion distance, hab. session 10.40.60.80.8-0.80.70.70.8-0.90.8-0.5
Locomotion velocity, hab. session 10.10.10.20.4-0.40.30.30.3-0.40.4-0.2
Time in familiar zone, hab. session 21.01.01.6-0.80.8-0.7-0.8-1.21.3-1.21.0
Time in novel zone, hab. session 20.70.71.70.3-0.30.20.31.0-1.21.2-1.3
Total zone transitions, hab. session 21.41.85.6-1.41.0-1.5-1.20.3-0.90.9-2.4
Total locomotion distance, hab. session 20.50.72.5-0.1-0.2-0.20.10.8-1.21.1-1.6
Locomotion velocity, hab. session 20.70.92.40.3-0.50.20.31.0-1.41.3-1.6
Novel to familiar place preference ratio0.20.20.6-0.30.1-0.3-0.10.2-0.50.5-0.8
Novelty place preference0.30.30.80.0-0.2-0.00.20.5-0.70.7-0.9
Time in novel zone, NPP test0.30.30.8-0.0-0.2-0.10.10.5-0.70.7-0.9
Total zone transitions, NPP test0.91.32.4-1.41.3-1.6-1.4-0.60.0-0.1-1.2
Total locomotion distance, NPP test0.10.20.70.0-0.0-0.1-0.00.3-0.60.5-0.8
Locomotion velocity, NPP test0.10.10.40.1-0.0-0.1-0.00.2-0.50.4-0.6
Intraocular pressure0.50.71.70.7-1.01.01.0-0.10.4-0.51.3
Delta distance traveled before/after self-admin0.10.10.40.0-0.50.40.60.1-0.20.10.1
Delta ambulatory time before/after self-admin0.00.00.1-0.2-0.10.20.4-0.10.1-0.10.3
Parametrial fat weight1.73.44.51.9-1.81.61.62.1-2.12.0-1.3
Pavlov. Cond. lever latency0.30.30.60.7-0.80.70.70.5-0.20.30.4
Pavlov. Cond. magazine entry latency0.50.72.10.1-0.20.00.20.9-1.11.1-1.4
Pavlov. Cond. change in total contacts0.50.61.00.6-0.50.50.50.9-1.01.0-0.9
Pavlov. Cond. index score0.00.00.00.10.00.00.00.1-0.20.1-0.2
Pavlov. Cond. latency score0.00.00.20.00.1-0.1-0.00.2-0.30.2-0.4
Pavlov. Cond. lever contacts0.10.10.3-0.30.5-0.4-0.4-0.20.0-0.2-0.3
Pavlov. Cond. magazine entry number0.00.00.1-0.20.1-0.2-0.2-0.00.00.0-0.0
Pavlov. Cond. intertrial magazine entries0.20.30.90.5-0.40.60.4-0.10.4-0.40.9
Pavlov. Cond. lever-magazine prob. diff.0.00.00.0-0.00.2-0.1-0.10.0-0.10.1-0.2
Pavlov. Cond. response bias0.00.00.00.1-0.00.10.10.1-0.20.1-0.2
Pavlov. Cond. lever latency0.00.00.10.2-0.10.20.1-0.00.0-0.10.2
Pavlov. Cond. magazine entry latency1.92.14.3-2.11.7-2.0-1.7-1.00.4-0.4-1.2
Pavlov. Cond. change in total contacts0.20.31.1-0.60.3-0.5-0.20.1-0.40.4-1.1
Pavlov. Cond. index score0.50.61.3-1.20.8-1.1-0.8-0.50.1-0.2-0.8
Pavlov. Cond. latency score0.40.41.0-1.00.7-0.9-0.6-0.40.1-0.2-0.7
Pavlov. Cond. lever contacts0.00.10.1-0.20.1-0.1-0.2-0.30.3-0.30.3
Pavlov. Cond. magazine entry number2.32.85.82.4-2.02.32.01.0-0.40.41.4
Pavlov. Cond. intertrial magazine entries1.21.62.71.7-1.61.61.61.1-0.70.70.4
Pavlov. Cond. lever-magazine prob. diff.0.70.91.9-1.41.0-1.3-1.0-0.60.2-0.3-0.8
Pavlov. Cond. response bias0.40.51.1-1.00.8-1.0-0.9-0.50.2-0.2-0.5
Time in closed arm before self-admin0.30.30.70.5-0.30.30.60.8-0.50.8-0.5
Time in closed arm after self-admin0.20.20.3-0.20.5-0.3-0.5-0.40.4-0.40.4
Time in open arm before self-admin0.40.40.9-0.60.4-0.4-0.4-0.90.7-1.00.4
Time in open arm after self-admin0.00.00.1-0.0-0.10.1-0.0-0.20.2-0.20.3
Bone: periosteal estimation0.10.30.30.5-0.60.50.60.6-0.60.5-0.3
Bone: periosteal perimeter0.30.50.80.4-0.60.40.70.8-0.90.8-0.8
Bone: post-yield work3.95.414.70.4-0.90.20.62.6-3.23.2-3.8
Progressive ratio test 1 active lever presses1.92.02.91.6-1.71.61.31.5-1.41.30.0
Progressive ratio test 1 breakpoint1.61.72.61.5-1.61.61.21.3-1.31.10.2
Progressive ratio test 1 inactive lever presses0.80.81.40.9-0.90.80.71.0-1.21.1-0.3
Progressive ratio test 2 active lever presses3.53.84.92.2-2.22.11.92.1-2.02.0-0.3
Progressive ratio test 2 breakpoint3.64.16.12.5-2.42.42.12.1-1.81.80.2
Progressive ratio test 2 inactive lever presses9.410.814.13.5-3.83.43.43.5-3.53.3-1.1
Incentive Sensitization - Responses0.50.50.70.6-0.80.70.70.8-0.80.8-0.2
Incentive Sensitization - Breakpoint0.70.70.80.9-0.90.90.80.9-0.80.9-0.2
Sum of active levers in priming session hrs 5-61.51.54.1-0.40.5-0.1-0.3-1.31.7-1.62.0
Progressive ratio1.41.64.7-1.71.0-1.5-1.0-0.1-0.60.6-2.2
Food seeking constrained by brief footshock0.20.20.6-0.70.4-0.6-0.1-0.50.3-0.4-0.2
Seeking ratio, punishment vs. effort0.91.13.01.3-0.81.21.2-0.00.5-0.51.7
Retroperitoneal fat weight4.514.921.94.7-4.54.54.53.9-3.23.2-0.5
Reaction time number correct0.91.22.0-0.81.0-0.8-1.0-1.31.4-1.31.1
Reaction time mean minus median0.91.22.9-1.71.3-1.5-1.4-0.60.2-0.0-0.7
Reaction time mean minus median AUC1.01.32.5-1.61.3-1.4-1.4-1.00.8-0.70.1
Reaction time num false alarms0.30.51.5-0.10.10.1-0.1-0.60.9-0.91.2
Reaction time num false alarms AUC0.71.01.6-0.80.8-0.6-0.8-1.11.3-1.21.1
Reaction time trials correct on left0.91.22.0-0.81.0-0.8-1.0-1.31.4-1.31.1
Reaction time trials on left1.11.52.4-0.91.1-0.9-1.1-1.41.5-1.51.2
Reaction time mean0.30.41.00.1-0.40.10.30.7-0.81.0-0.8
Reaction time mean AUC0.40.51.30.2-0.40.20.30.9-1.01.2-0.9
Median of all reaction times0.60.81.70.5-0.70.40.61.0-1.11.3-1.0
Reaction time omissions1.41.93.1-1.81.6-1.6-1.6-1.31.1-1.00.3
Reaction time false alarm rate0.10.10.4-0.20.1-0.0-0.1-0.40.5-0.50.7
Reaction time premature initiation rate2.33.14.6-2.12.1-2.0-2.2-1.71.5-1.40.3
Reaction time premature initiations4.36.17.9-2.72.7-2.5-2.8-2.62.4-2.31.1
Std. dev. reaction times0.20.30.7-0.80.4-0.6-0.50.1-0.20.4-0.6
Reaction time trials completed1.11.52.4-0.91.1-0.9-1.1-1.41.5-1.51.2
Reaction time trials AUC0.81.11.8-0.81.0-0.8-1.0-1.21.3-1.31.0
Run reversals in cocaine runway, females0.90.91.9-1.20.9-1.2-1.0-0.1-0.50.5-1.4
Run reversals in cocaine runway, males0.60.61.6-0.40.5-0.3-0.1-0.81.3-0.91.1
Latency to leave start box in cocaine runway0.60.61.80.2-0.30.10.30.8-1.11.0-1.3
Latency to leave start box in cocaine runway, F0.30.31.2-0.00.0-0.20.30.5-0.50.7-1.1
Latency to leave start box in cocaine runway, M0.00.00.10.1-0.20.2-0.20.2-0.30.2-0.2
Std. dev. time between licks in bursts1.11.42.3-0.70.9-0.6-0.9-1.41.5-1.51.5
Total sessions with >9 infusions0.91.01.71.0-0.90.80.71.2-1.31.2-0.6
Short access day 1 total inactive lever presses3.43.86.42.0-2.12.02.52.0-1.91.9-0.5
Short access day 10 total inactive lever presses1.71.83.61.4-1.61.41.91.3-1.21.1-0.4
Short access day 1 total infusions3.73.95.31.7-2.01.71.92.3-2.32.3-1.3
Short access day 10 total infusions2.83.16.50.9-1.00.50.92.1-2.42.6-2.3
Short access total infusions1.71.94.00.9-1.00.70.71.7-1.92.0-1.4
Short access day 1 locomotion2.32.44.31.4-1.51.21.21.8-2.11.9-1.3
Short access day 10 total locomotion1.01.12.10.8-0.70.50.61.3-1.51.4-1.1
Short access total locomotion1.11.12.60.7-0.70.50.51.3-1.61.4-1.1
One hour access (0.3 mA shock)8.39.713.43.6-3.73.53.23.3-3.03.0-0.6
Compulsive drug intake3.83.95.1-2.31.9-1.8-2.2-2.21.9-2.11.2
One hour access (shock baseline)8.910.315.23.9-3.73.63.43.4-3.02.9-0.6
Social response proportion0.60.61.3-1.20.9-1.0-1.0-0.2-0.10.2-0.7
Social responses0.91.12.3-1.01.4-1.1-1.5-0.90.8-0.80.5
Social time0.71.01.8-1.11.3-1.2-1.4-0.80.6-0.6-0.0
Soleus weight2.67.514.63.8-3.33.73.32.3-1.41.41.1
Bone: stiffness0.81.23.8-1.30.9-1.4-0.8-0.0-0.60.5-1.9
Tibialis anterior weight9.030.739.4-5.66.0-5.5-5.5-6.35.8-5.93.2
Time to tail flick, vehicle, before self-admin0.60.63.0-0.80.2-0.70.10.4-0.60.7-1.7
Time to tail flick, vehicle, after self-admin2.12.24.0-1.81.9-1.9-2.0-1.30.7-0.9-0.4
Time to tail flick, test, before self-admin0.90.92.70.0-0.1-0.20.11.0-1.21.4-1.6
Time to tail flick, test, after self-admin0.20.20.6-0.50.6-0.5-0.1-0.40.8-0.50.1
Delta time to tail flick, vehicle, before/after SA1.51.53.9-1.01.6-1.3-2.0-1.10.7-0.90.4
Delta time to tail flick, test, before/after SA2.72.45.2-0.80.9-0.6-0.6-1.72.3-2.22.0
Tibia length0.41.12.8-0.40.5-0.2-0.4-1.21.5-1.51.7
Ambulatory time before self-admin0.10.10.3-0.20.1-0.2-0.2-0.10.0-0.0-0.5
Ambulatory time after self-admin1.11.21.80.7-1.00.81.11.2-1.21.3-1.2
Bone: tissue strength0.20.10.30.3-0.20.20.30.5-0.50.4-0.5
Total heroin consumption3.84.47.0-2.52.5-2.5-2.6-2.01.7-1.70.3
Bone: trabecular number0.71.14.7-0.80.2-0.7-0.40.6-1.11.1-2.2
Bone: trabecular spacing0.20.31.10.40.10.20.1-0.40.6-0.71.1
Bone: trabecular thickness1.61.93.20.8-1.20.91.01.7-1.71.8-1.7
Bone: trabecular tissue density3.34.79.13.0-2.62.92.61.7-1.01.01.1
Water consumed over 24 hours0.40.51.0-1.00.9-1.0-0.8-0.60.3-0.4-0.5
Number of responses in last shaping day0.60.61.00.9-1.01.00.40.8-0.90.70.2