Hub : Genes

Phyhip

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc intron excision ratio chr15_51944744_51947752 0.03 0.03 4.6e-04 0.01 0.02 0.01 0.01 3.6e-03 1.7e-03 2.4e-02 1.9e-02
2 NAcc intron excision ratio chr15_51943945_51947752 0.02 0.03 1.4e-03 0.01 0.01 0.01 0.01 5.1e-03 3.8e-03 3.3e-02 2.4e-02
3 BLA alternative TSS XM_039093159.2 0.14 0.12 7.7e-06 0.08 0.08 0.08 0.09 4.0e-05 3.5e-05 6.7e-05 2.8e-05
4 BLA alternative TSS NM_001017376.1 0.14 0.12 6.3e-06 0.08 0.08 0.07 0.08 4.8e-05 3.8e-05 8.2e-05 3.3e-05
5 Eye gene expression Phyhip 0.79 0.16 1.3e-10 0.49 0.48 0.44 0.45 5.3e-09 9.4e-09 4.1e-08 3.1e-08
6 BLA isoform ratio XM_039093159.2 0.1 0.09 4.6e-04 0.05 0.05 0.04 0.05 1.7e-03 1.8e-03 3.7e-03 1.8e-03
7 BLA isoform ratio NM_001017376.1 0.1 0.09 3.4e-04 0.05 0.05 0.04 0.05 1.3e-03 1.3e-03 2.4e-03 1.3e-03
8 BLA intron excision ratio chr15_51944744_51947752 0.1 0.09 6.7e-04 0.03 0.04 0.03 0.03 1.7e-02 2.4e-03 9.3e-03 7.4e-03
9 PL intron excision ratio chr15_51944744_51947752 0.04 0.04 3.2e-04 0.02 0.03 0.02 0.02 1.2e-03 7.0e-04 1.5e-03 3.4e-03
10 LHb gene expression Phyhip 0.47 0.25 7.3e-08 0.15 0.22 0.19 0.18 2.1e-04 6.7e-06 2.9e-05 4.6e-05
11 PL alternative TSS XM_039093159.2 0.03 0.03 4.0e-03 0.01 0.01 0 0 3.0e-02 3.6e-02 3.1e-01 9.9e-02
12 pVTA gene expression Phyhip 0.45 0.62 3.9e-07 0.07 0.09 0.1 0.1 1.2e-06 2.6e-07 8.6e-09 1.5e-08
13 RMTg gene expression Phyhip 0.86 0.13 2.7e-04 0.1 0.12 0.07 0.1 1.7e-03 4.1e-04 5.8e-03 1.2e-03
14 Brain alternative TSS NM_001017376.1 0.12 0.13 2.7e-07 0.07 0.07 0.07 0.07 2.1e-07 8.1e-07 3.9e-07 7.0e-07
15 Brain isoform ratio NM_001017376.1 0.09 0.09 3.0e-06 0.06 0.05 0.05 0.04 1.5e-06 2.8e-05 2.7e-05 6.4e-05
16 Brain isoform ratio XM_039093159.2 0.08 0.09 4.2e-06 0.06 0.05 0.04 0.04 2.2e-06 3.6e-05 4.3e-05 6.2e-05
17 IC gene expression Phyhip 0.07 0.07 5.5e-03 0.05 0.04 0.04 0.04 4.6e-03 7.6e-03 1.3e-02 1.0e-02
18 Brain alternative TSS XM_039093159.2 0.11 0.12 7.0e-07 0.07 0.06 0.06 0.06 4.7e-07 3.3e-06 1.8e-06 3.2e-06
19 Brain intron excision ratio chr15_51943945_51947752 0.75 0.17 9.4e-06 0.07 0.05 0.08 0.08 8.4e-07 9.3e-06 1.1e-07 1.3e-07
20 Brain intron excision ratio chr15_51944744_51947752 0.74 0.18 6.8e-06 0.07 0.06 0.08 0.08 4.6e-07 5.7e-06 1.1e-07 8.7e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density1.01.82.11.4-1.41.4-1.4-1.4-1.4-1.41.41.4-1.4-1.40.9-1.41.31.3-1.3-1.3-1.31.31.0
Area under the delay curve0.10.10.6-0.20.2-0.40.40.40.40.4-0.2-0.20.30.3-0.80.4-0.3-0.30.30.30.3-0.3-0.7
BMI with tail0.31.21.5-1.21.2-1.21.21.21.21.2-1.2-1.21.21.20.10.8-1.1-1.11.11.11.1-1.0-0.3
BMI without tail0.00.21.70.0-0.0-0.10.10.10.10.10.00.0-0.1-0.11.3-0.40.30.3-0.3-0.3-0.30.31.1
Body weight0.62.63.1-1.71.7-1.71.71.71.71.7-1.7-1.71.71.8-1.11.5-1.6-1.61.61.61.6-1.6-1.3
Weight adjusted by age0.82.22.4-1.51.5-1.51.51.51.51.5-1.5-1.51.51.5-1.41.4-1.5-1.51.51.51.5-1.5-1.5
Bone surface0.40.81.01.0-1.01.0-1.0-1.0-1.0-1.01.01.0-1.0-1.00.1-0.80.70.7-0.7-0.7-0.70.70.3
Bone volume0.51.01.21.1-1.11.1-1.1-1.1-1.1-1.11.11.1-1.1-1.10.3-0.90.90.9-0.9-0.9-0.90.90.5
Breakpoint value in progressive ratio session0.10.10.1-0.30.3-0.30.30.30.30.3-0.3-0.30.30.3-0.40.2-0.3-0.30.30.30.3-0.3-0.4
Number of licking bursts0.00.00.00.0-0.00.1-0.1-0.1-0.1-0.10.00.0-0.0-0.00.2-0.10.10.1-0.1-0.1-0.10.10.2
Context. condit. distance diff. score1.61.98.31.0-1.01.0-1.0-1.0-1.0-1.01.01.1-1.1-1.12.9-1.61.21.2-1.2-1.2-1.21.32.5
Locomotion velocity, session 10.20.20.3-0.40.4-0.50.50.50.50.5-0.4-0.40.40.4-0.40.5-0.5-0.50.50.50.5-0.5-0.5
Locomotion distance, session 10.10.10.80.2-0.20.1-0.1-0.1-0.1-0.10.20.2-0.1-0.2-0.90.20.30.3-0.3-0.3-0.30.2-0.5
Locomotion velocity, session 20.00.00.20.2-0.20.1-0.1-0.1-0.1-0.10.20.2-0.2-0.2-0.5-0.00.20.2-0.2-0.2-0.20.2-0.3
Locomotion distance, session 20.10.22.30.1-0.10.1-0.1-0.1-0.1-0.10.10.1-0.1-0.1-1.50.30.20.2-0.2-0.2-0.20.2-0.9
Locomotion velocity, session 30.50.50.7-0.70.7-0.80.80.80.80.8-0.7-0.70.70.70.60.3-0.8-0.80.80.80.8-0.70.1
Locomotion distance, session 30.10.11.00.2-0.20.1-0.1-0.1-0.1-0.10.20.2-0.2-0.21.0-0.40.10.1-0.1-0.1-0.10.20.7
Stereotopy head waving bouts, day 30.60.70.9-0.90.9-1.01.01.01.01.0-0.9-0.90.90.9-0.70.8-0.8-0.80.80.80.8-0.8-0.7
Stereotopy head waving duration, day 32.32.83.0-1.71.7-1.71.71.71.71.7-1.7-1.71.71.7-1.51.7-1.6-1.61.61.61.6-1.6-1.5
Locomotion velocity, session 75.05.514.62.1-2.12.1-2.1-2.1-2.1-2.12.12.2-2.2-2.13.8-2.82.12.1-2.1-2.1-2.12.23.3
Locomotion distance, session 73.74.710.72.0-2.02.0-2.0-2.0-2.0-2.02.02.0-2.0-2.03.3-2.62.02.0-2.0-2.0-2.02.13.0
Stereotopy head waving bouts, day 71.61.92.6-1.31.3-1.31.31.31.31.3-1.3-1.31.41.4-1.61.4-1.4-1.41.41.41.4-1.4-1.6
Stereotopy head waving duration, day 72.22.73.2-1.61.6-1.51.51.51.51.5-1.6-1.61.61.6-1.61.7-1.7-1.71.71.71.7-1.7-1.8
Locomotion velocity, session 80.00.10.60.0-0.0-0.00.00.00.00.00.10.1-0.1-0.00.8-0.40.00.0-0.0-0.0-0.00.10.5
Locomotion distance, session 80.71.11.41.0-1.00.9-0.9-0.9-0.9-0.91.01.0-1.0-1.01.0-1.11.21.2-1.2-1.2-1.21.21.2
Degree of sensitization distance4.44.76.22.1-2.12.1-2.1-2.1-2.1-2.12.12.1-2.1-2.12.5-2.42.12.1-2.1-2.1-2.12.22.5
Degree of sensitization stereotypy1.11.21.4-1.11.1-1.01.01.01.01.0-1.1-1.11.11.1-1.11.1-1.1-1.11.11.11.1-1.1-1.2
Conditioned locomotion0.10.10.60.2-0.20.2-0.2-0.2-0.2-0.20.20.2-0.2-0.20.7-0.40.20.2-0.2-0.2-0.20.20.5
Cocaine response after cond. corrected0.20.30.9-0.60.6-0.60.60.60.60.6-0.5-0.50.50.50.90.1-0.5-0.50.50.50.5-0.50.5
Cocaine response after cond. not corrected0.10.20.4-0.40.4-0.40.40.40.40.4-0.4-0.40.40.40.60.1-0.4-0.40.40.40.4-0.40.3
Cocaine response before conditioning0.20.20.70.4-0.40.4-0.4-0.4-0.4-0.40.40.4-0.4-0.4-0.8-0.10.50.5-0.5-0.5-0.50.4-0.4
Saline control response0.10.10.40.4-0.40.3-0.3-0.3-0.3-0.30.30.3-0.3-0.4-0.6-0.00.20.2-0.2-0.2-0.20.2-0.4
Bone: connectivity density2.23.53.81.9-1.91.9-1.9-1.9-1.9-1.91.91.9-1.9-1.91.5-1.91.91.9-1.9-1.9-1.91.91.6
Bone: cortical apparent density0.20.32.60.3-0.30.3-0.3-0.3-0.3-0.30.30.3-0.3-0.31.6-0.70.30.3-0.3-0.3-0.30.41.2
Bone: cortical area0.00.00.40.0-0.0-0.00.00.00.00.00.00.0-0.00.0-0.60.0-0.1-0.10.10.10.1-0.2-0.5
Bone: cortical porosity1.41.53.5-1.11.1-1.11.11.11.11.1-1.1-1.11.21.1-1.91.4-1.1-1.11.11.11.1-1.2-1.7
Bone: cortical porosity0.91.03.2-0.80.8-0.90.90.90.90.9-0.9-0.90.90.9-1.81.2-0.8-0.80.80.80.8-0.9-1.5
Bone: cortical thickness0.00.00.00.0-0.00.0-0.0-0.0-0.0-0.00.10.1-0.1-0.0-0.1-0.1-0.1-0.10.10.10.1-0.1-0.1
Bone: cortical thickness0.10.10.80.0-0.00.0-0.0-0.0-0.0-0.00.10.1-0.1-0.00.9-0.40.30.3-0.3-0.3-0.30.30.8
Bone: cortical tissue density0.20.43.00.3-0.30.3-0.3-0.3-0.3-0.30.30.3-0.4-0.31.7-0.80.40.4-0.4-0.4-0.40.41.3
Condit. Reinf. active minus inactive responses0.50.51.3-0.70.7-0.70.70.70.70.7-0.7-0.70.70.7-1.10.8-0.6-0.60.60.60.6-0.6-0.9
Condit. Reinf. active-inactive response ratio1.92.12.4-1.51.5-1.61.61.61.61.6-1.5-1.51.51.5-0.81.3-1.4-1.41.41.41.4-1.4-1.1
Condit. Reinf. active responses0.10.11.10.0-0.0-0.10.10.10.10.1-0.0-0.00.00.0-1.00.30.00.0-0.0-0.0-0.0-0.0-0.7
Condit. Reinf. inactive responses2.02.53.11.8-1.81.7-1.7-1.7-1.7-1.71.71.7-1.7-1.7-0.2-1.21.71.7-1.7-1.7-1.71.60.4
Incentive salience index mean0.81.03.3-0.90.9-1.01.01.01.01.0-0.9-0.90.90.9-1.81.2-0.8-0.80.80.80.8-0.8-1.5
Condit. Reinf. lever presses0.40.63.2-0.60.6-0.70.70.70.70.7-0.6-0.60.60.6-1.81.0-0.4-0.40.40.40.4-0.5-1.3
Condit. Reinf. active minus inactive responses0.20.40.40.7-0.70.7-0.7-0.7-0.7-0.70.70.7-0.7-0.70.5-0.60.60.6-0.6-0.6-0.60.60.5
Condit. Reinf. active-inactive response ratio0.00.10.1-0.30.3-0.20.20.20.20.2-0.2-0.20.20.20.20.1-0.3-0.30.30.30.3-0.30.0
Condit. Reinf. active responses0.81.11.21.1-1.11.1-1.1-1.1-1.1-1.11.11.1-1.1-1.10.7-1.01.11.1-1.1-1.1-1.11.10.8
Condit. Reinf. inactive responses1.62.42.71.6-1.61.6-1.6-1.6-1.6-1.61.61.6-1.6-1.60.7-1.41.71.7-1.7-1.7-1.71.61.1
Condit. Reinf. lever presses0.20.20.60.5-0.50.5-0.5-0.5-0.5-0.50.40.4-0.4-0.4-0.8-0.10.60.6-0.6-0.6-0.60.5-0.3
Condit. Reinf. lever reinforcers received0.60.80.91.0-1.01.0-1.0-1.0-1.0-1.01.01.0-1.0-1.00.5-0.90.90.9-0.9-0.9-0.90.90.7
Conditioned reinforcement - actives0.51.82.31.3-1.31.3-1.3-1.3-1.3-1.31.31.3-1.3-1.31.5-1.41.31.3-1.3-1.3-1.31.41.5
Conditioned reinforcement - inactives1.54.14.72.2-2.22.1-2.1-2.1-2.1-2.12.22.2-2.1-2.10.8-1.92.12.1-2.1-2.1-2.12.11.3
Conditioned locomotion0.10.20.40.4-0.40.4-0.4-0.4-0.4-0.40.40.4-0.4-0.40.6-0.60.40.4-0.4-0.4-0.40.50.6
Patch foraging indifference point 0 sec0.82.23.21.8-1.81.7-1.7-1.7-1.7-1.71.71.7-1.7-1.7-0.6-1.21.21.2-1.2-1.2-1.21.2-0.2
Patch foraging indifference point AUC0.10.30.4-0.50.5-0.60.60.60.60.6-0.5-0.50.50.50.30.5-0.5-0.50.50.50.5-0.5-0.0
Delay disc. indifference point, 0s delay0.30.30.50.6-0.60.5-0.5-0.5-0.5-0.50.60.6-0.6-0.7-0.7-0.20.50.5-0.5-0.5-0.50.5-0.3
Delay disc. indifference point, 16s delay0.10.20.30.5-0.50.4-0.4-0.4-0.4-0.40.50.5-0.5-0.40.1-0.50.50.5-0.5-0.5-0.50.50.2
Delay disc. indifference point, 2s delay1.71.93.3-1.21.2-1.31.31.31.31.3-1.3-1.31.31.3-1.81.5-1.3-1.31.31.31.3-1.4-1.7
Delay disc. indifference point, 24s delay0.10.10.3-0.40.4-0.50.50.50.50.5-0.4-0.40.40.50.10.2-0.4-0.40.40.40.4-0.3-0.1
Delay disc. indifference point, 4s delay1.81.92.1-1.31.3-1.51.51.51.51.5-1.3-1.31.31.3-1.21.4-1.4-1.41.41.41.4-1.4-1.3
Delay disc. indifference point, 8s delay0.00.00.10.2-0.20.1-0.1-0.1-0.1-0.10.20.2-0.2-0.2-0.3-0.10.20.2-0.2-0.2-0.20.1-0.2
Indifference point function ln k0.00.10.70.0-0.00.0-0.0-0.0-0.0-0.00.00.0-0.0-0.0-0.80.20.20.2-0.2-0.2-0.20.1-0.5
Indifference point function log k0.00.10.70.0-0.00.0-0.0-0.0-0.0-0.00.00.0-0.0-0.0-0.80.20.20.2-0.2-0.2-0.20.1-0.5
Patch foraging total patch changes 0 sec0.51.62.31.5-1.51.4-1.4-1.4-1.4-1.41.51.5-1.4-1.4-0.8-0.91.01.0-1.0-1.0-1.00.9-0.4
Patch foraging total patch changes 12 sec0.40.50.90.9-0.90.9-0.9-0.9-0.9-0.90.90.9-0.9-0.9-0.5-0.40.50.5-0.5-0.5-0.50.4-0.4
Patch foraging total patch changes 18 sec0.71.72.11.5-1.51.3-1.3-1.3-1.3-1.31.41.4-1.4-1.40.7-1.21.21.2-1.2-1.2-1.21.20.8
Patch foraging total patch changes 24 sec0.10.21.50.0-0.00.0-0.0-0.0-0.0-0.0-0.0-0.00.00.0-1.20.4-0.3-0.30.30.30.3-0.4-1.1
Patch foraging total patch changes 6 sec0.10.20.30.6-0.60.5-0.5-0.5-0.5-0.50.50.5-0.5-0.60.1-0.40.30.3-0.3-0.3-0.30.30.0
Patch foraging time to switch 0 sec0.31.21.41.1-1.11.2-1.2-1.2-1.2-1.21.11.1-1.1-1.01.0-1.21.11.1-1.1-1.1-1.11.11.0
Patch foraging water rate 0 sec0.20.61.3-0.70.7-0.80.80.80.80.8-0.7-0.80.80.8-1.10.9-0.7-0.70.70.70.7-0.7-1.0
Patch foraging water rate 12 sec0.31.11.4-1.01.0-1.11.11.11.11.1-1.0-1.01.01.0-1.21.2-1.0-1.01.01.01.0-1.0-1.2
Patch foraging water rate 18 sec1.73.94.4-2.12.1-2.02.02.02.02.0-2.1-2.12.12.1-1.21.9-2.0-2.02.02.02.0-2.0-1.4
Patch foraging water rate 24 sec0.10.20.3-0.50.5-0.50.50.50.50.5-0.5-0.50.50.50.40.3-0.3-0.30.30.30.3-0.30.2
Patch foraging water rate 6 sec2.23.35.3-1.71.7-1.81.81.81.81.8-1.7-1.71.71.7-2.31.9-1.8-1.81.81.81.8-1.8-2.2
Seeking ratio, delayed vs. immediate footshock0.70.91.11.0-1.01.1-1.1-1.1-1.1-1.11.01.0-1.0-1.00.4-0.81.01.0-1.0-1.0-1.01.00.6
Distance traveled before self-admin0.61.33.3-1.01.0-1.01.01.01.01.0-1.0-1.01.01.0-1.81.3-1.1-1.11.11.11.1-1.1-1.7
Distance traveled after self-admin1.62.93.2-1.81.8-1.71.71.71.71.7-1.8-1.81.81.8-1.01.6-1.7-1.71.71.71.7-1.7-1.3
Extensor digitorum longus weight12.148.351.1-7.17.1-7.27.27.27.27.2-7.1-7.17.17.1-5.26.8-7.0-7.07.07.07.0-7.0-6.0
Bone: elastic displacement0.40.50.60.7-0.70.7-0.7-0.7-0.7-0.70.70.7-0.7-0.7-0.3-0.40.80.8-0.8-0.8-0.80.70.1
Bone: elastic work0.20.31.20.5-0.50.5-0.5-0.5-0.5-0.50.50.5-0.5-0.5-1.1-0.10.50.5-0.5-0.5-0.50.4-0.6
Bone: endosteal estimation0.10.20.8-0.40.4-0.40.40.40.40.4-0.4-0.40.40.4-0.90.5-0.5-0.50.50.50.5-0.5-0.8
Bone: endosteal perimeter0.10.21.3-0.20.3-0.30.30.30.30.3-0.3-0.30.30.3-1.10.5-0.4-0.40.40.40.4-0.4-1.0
Epididymis fat weight0.62.93.51.6-1.61.7-1.7-1.7-1.7-1.71.61.6-1.6-1.61.4-1.81.91.9-1.9-1.9-1.91.91.7
Delta time in closed arm before/after self-admin3.73.44.02.0-2.01.9-1.9-1.9-1.9-1.92.02.0-2.0-2.00.8-1.71.91.9-1.9-1.9-1.91.91.2
Delta time in open arm before/after self-admin0.10.10.1-0.30.3-0.30.30.30.30.3-0.3-0.30.30.3-0.10.2-0.2-0.20.20.20.2-0.2-0.1
Diff in mean of infusions in LGA sessions0.61.11.1-1.01.0-1.11.11.11.11.1-1.0-1.01.01.1-0.91.0-1.0-1.01.01.01.0-1.0-1.0
Delay discount exponential model param0.40.51.00.6-0.60.7-0.7-0.7-0.7-0.70.60.6-0.6-0.61.0-0.80.60.6-0.6-0.6-0.60.70.9
Extinction: sum of active levers before priming1.52.32.71.5-1.51.6-1.6-1.6-1.6-1.61.51.5-1.5-1.51.0-1.51.51.5-1.5-1.5-1.51.51.2
Active lever presses in extinction session 60.70.71.00.8-0.80.7-0.7-0.7-0.7-0.70.80.8-0.8-0.81.0-1.00.80.8-0.8-0.8-0.80.91.0
Bone: final force0.10.20.4-0.40.4-0.40.40.40.40.4-0.4-0.40.40.4-0.70.4-0.5-0.50.50.50.5-0.5-0.6
Bone: final moment0.10.20.8-0.30.3-0.40.40.40.40.4-0.3-0.30.30.4-0.90.4-0.4-0.40.40.40.4-0.4-0.8
Food consumed during 24 hour testing period0.20.30.50.6-0.60.6-0.6-0.6-0.6-0.60.60.6-0.6-0.6-0.4-0.30.70.7-0.7-0.7-0.70.6-0.0
Glucose0.00.10.7-0.0-0.00.0-0.0-0.0-0.0-0.00.00.0-0.0-0.00.8-0.3-0.1-0.10.10.10.1-0.10.5
Heart weight0.30.40.60.8-0.80.7-0.7-0.7-0.7-0.70.80.8-0.8-0.80.1-0.60.50.5-0.5-0.5-0.50.50.1
Delay discount hyperbolic model param0.50.61.20.7-0.70.8-0.8-0.8-0.8-0.80.70.7-0.7-0.71.1-0.80.70.7-0.7-0.7-0.70.81.0
Intermittent access intake day 1-15 change0.63.43.51.9-1.91.9-1.9-1.9-1.9-1.91.91.9-1.9-1.91.4-1.91.91.9-1.9-1.9-1.91.91.6
Intermittent access intake escalation0.63.43.71.9-1.91.9-1.9-1.9-1.9-1.91.91.9-1.9-1.91.2-1.81.91.9-1.9-1.9-1.91.91.5
Intermittent access intake escalation 21.01.72.01.3-1.31.3-1.3-1.3-1.3-1.31.31.3-1.3-1.31.2-1.41.31.3-1.3-1.3-1.31.31.3
Intermitt. access day 1 inactive lever presses0.00.00.10.1-0.10.1-0.1-0.1-0.1-0.10.10.1-0.1-0.10.3-0.20.10.1-0.1-0.1-0.10.10.2
Intermitt. access day 15 inactive lever presses0.00.00.10.2-0.20.2-0.2-0.2-0.2-0.20.20.2-0.2-0.2-0.1-0.10.20.2-0.2-0.2-0.20.2-0.0
Intermitt. access escalation Index0.00.10.2-0.20.2-0.20.20.20.20.2-0.2-0.20.20.2-0.50.2-0.2-0.20.20.20.2-0.3-0.5
Intermittent access day 1 total infusions0.00.00.0-0.00.0-0.00.00.00.00.0-0.0-0.00.00.0-0.10.0-0.0-0.00.00.00.0-0.0-0.1
Intermittent access day 15 total infusions0.92.32.61.6-1.61.6-1.6-1.6-1.6-1.61.61.6-1.6-1.60.8-1.51.61.6-1.6-1.6-1.61.51.1
Intermittent access terminal intake (last 3 days)0.81.41.61.2-1.21.2-1.2-1.2-1.2-1.21.21.2-1.2-1.21.1-1.31.21.2-1.2-1.2-1.21.21.2
Intermittent access total infusions1.21.41.71.2-1.21.2-1.2-1.2-1.2-1.21.21.2-1.2-1.21.1-1.31.21.2-1.2-1.2-1.21.21.2
Intermittent access day 1 locomotion0.00.00.30.1-0.10.1-0.1-0.1-0.1-0.10.10.1-0.1-0.1-0.60.10.00.0-0.0-0.0-0.00.0-0.4
Intermittent access day 15 total locomotion0.10.50.70.6-0.70.6-0.6-0.6-0.6-0.60.70.7-0.7-0.60.8-0.80.70.7-0.7-0.7-0.70.70.7
Intermittent access total locomotion0.10.10.20.4-0.40.3-0.3-0.3-0.3-0.30.40.4-0.4-0.30.2-0.40.40.4-0.4-0.4-0.40.30.3
Intermittent access standard deviation0.10.30.30.6-0.60.5-0.5-0.5-0.5-0.50.60.6-0.6-0.50.1-0.50.50.5-0.5-0.5-0.50.50.2
Left kidney weight0.00.30.9-0.40.4-0.50.50.50.50.5-0.5-0.50.50.5-0.90.6-0.4-0.40.40.40.4-0.5-0.8
Right kidney weight0.10.52.6-0.30.3-0.30.30.30.30.3-0.3-0.30.30.3-1.60.7-0.7-0.70.70.70.7-0.7-1.5
Cocaine induced anxiety0.10.22.4-0.00.0-0.00.00.00.00.0-0.1-0.10.10.0-1.60.5-0.2-0.20.20.20.2-0.2-1.2
Post-drug Anxiety0.70.81.01.0-1.01.0-1.0-1.0-1.0-1.01.01.0-1.0-1.0-0.7-0.50.90.9-0.9-0.9-0.90.8-0.2
Baseline Anxiety0.40.61.40.7-0.70.7-0.7-0.7-0.7-0.70.70.7-0.7-0.71.2-0.90.80.8-0.8-0.8-0.80.81.1
Tail length0.31.62.01.4-1.41.3-1.3-1.3-1.3-1.31.41.4-1.4-1.40.2-1.11.31.3-1.3-1.3-1.31.30.6
Length with tail0.10.42.1-0.40.4-0.40.40.40.40.4-0.5-0.50.50.5-1.40.7-0.6-0.60.60.60.6-0.7-1.3
Length without tail1.47.58.6-2.72.7-2.62.62.62.62.6-2.7-2.72.72.7-2.72.8-2.9-2.92.92.92.9-2.9-2.9
Times rat made contact with spout0.60.70.90.8-0.80.8-0.8-0.8-0.8-0.80.80.8-0.8-0.80.8-0.90.90.9-0.9-0.9-0.90.90.9
Lifetime Intake0.70.91.10.9-0.90.9-0.9-0.9-0.9-0.90.90.9-0.9-0.91.0-1.10.90.9-0.9-0.9-0.91.01.0
Liver weight, left1.73.05.6-1.71.7-1.71.71.71.71.7-1.7-1.71.71.7-2.42.1-1.5-1.51.51.51.5-1.5-2.0
Liver weight, right0.40.60.9-0.90.9-0.90.90.90.90.9-0.9-0.90.90.9-0.40.8-0.6-0.60.60.60.6-0.6-0.4
Locomotor activity2.43.714.9-1.61.6-1.71.71.71.71.7-1.6-1.61.71.6-3.92.4-1.6-1.61.61.61.6-1.7-3.2
Locomotor testing distance0.20.66.90.3-0.30.1-0.1-0.1-0.1-0.10.20.2-0.2-0.2-2.60.70.20.2-0.2-0.2-0.20.1-1.8
Locomotor testing rearing0.20.77.90.6-0.50.4-0.4-0.4-0.4-0.40.50.4-0.4-0.5-2.80.60.40.4-0.4-0.4-0.40.3-1.8
Locomotion in novel chamber0.40.50.60.8-0.80.7-0.7-0.7-0.7-0.70.80.8-0.8-0.80.2-0.60.70.7-0.7-0.7-0.70.70.4
Locomotion in novel chamber post-restriction0.41.11.2-1.11.1-1.01.01.01.01.0-1.1-1.11.11.1-0.81.0-1.1-1.11.11.11.1-1.1-0.9
Fecal boli incidents, locomotor time 10.51.41.9-1.11.1-1.11.11.11.11.1-1.2-1.21.21.2-1.31.1-1.2-1.21.21.21.2-1.2-1.4
Change in fecal boli incidents, locomotor task0.20.20.3-0.50.5-0.50.50.50.50.5-0.5-0.50.50.50.10.3-0.5-0.50.50.50.5-0.4-0.1
Time >=10cm from walls, locomotor time 10.81.01.11.1-1.11.0-1.0-1.0-1.0-1.01.11.1-1.1-1.00.6-1.11.01.0-1.0-1.0-1.01.00.8
Bouts of movement, locomotor time 13.74.95.5-2.32.3-2.42.42.42.42.4-2.3-2.32.32.1-1.22.2-2.2-2.22.22.22.2-2.2-1.6
Total resting periods, locomotor time 14.04.65.4-2.32.3-2.32.32.32.32.3-2.2-2.22.22.1-0.82.0-2.2-2.22.22.22.2-2.1-1.3
Rest time, locomotor task time 11.32.12.4-1.51.5-1.51.51.51.51.5-1.5-1.51.51.4-0.51.4-1.5-1.51.51.51.5-1.4-0.8
Distance moved, locomotor task time 11.13.13.51.9-1.91.7-1.7-1.7-1.7-1.71.91.9-1.9-1.71.3-1.91.81.8-1.8-1.8-1.81.81.5
Vertical activity count, locomotor time 10.10.91.11.1-1.11.0-1.0-1.0-1.0-1.01.01.0-1.0-1.0-0.3-0.61.01.0-1.0-1.0-1.00.90.1
Time >=10cm from walls, locomotor time 20.20.50.6-0.70.7-0.70.70.70.70.7-0.7-0.70.70.6-0.40.8-0.7-0.70.70.70.7-0.7-0.5
Bouts of movement, locomotor time 21.54.85.4-2.32.3-2.32.32.32.32.3-2.3-2.32.22.2-1.32.2-2.2-2.22.22.22.2-2.2-1.7
Total resting periods, locomotor time 21.35.25.8-2.42.4-2.42.42.42.42.4-2.4-2.42.42.3-1.42.3-2.3-2.32.32.32.3-2.3-1.8
Rest time, locomotor task time 20.61.01.3-1.11.1-1.11.11.11.11.1-1.1-1.11.11.0-0.01.1-1.0-1.01.01.01.0-1.0-0.3
Distance moved, locomotor task time 22.43.13.71.9-1.91.8-1.8-1.8-1.8-1.81.91.9-1.9-1.80.6-1.71.81.8-1.8-1.8-1.81.81.0
Vertical activity count, locomotor time 20.20.40.60.7-0.70.7-0.7-0.7-0.7-0.70.70.7-0.7-0.7-0.5-0.30.60.6-0.6-0.6-0.60.6-0.1
Light reinforcement 11.25.76.62.2-2.22.3-2.3-2.3-2.3-2.32.32.3-2.3-2.22.2-2.62.52.5-2.5-2.5-2.52.62.5
Light reinforcement 20.92.06.01.1-1.11.2-1.2-1.2-1.2-1.21.11.2-1.2-1.12.5-1.81.31.3-1.3-1.3-1.31.42.2
Bone: marrow area0.10.10.6-0.20.2-0.20.20.20.20.2-0.2-0.20.30.2-0.80.4-0.4-0.40.40.40.4-0.4-0.7
Bone: maximum diameter0.40.71.0-0.80.8-0.80.80.80.80.8-0.8-0.80.80.8-0.60.7-1.0-1.01.01.01.0-1.0-0.9
Bone: maximum force0.30.71.5-0.70.7-0.70.70.70.70.7-0.7-0.70.70.7-1.20.8-0.9-0.90.90.90.9-0.9-1.2
Bone: maximum moment0.30.62.1-0.50.5-0.60.60.60.60.6-0.5-0.50.50.6-1.50.7-0.7-0.70.70.70.7-0.8-1.3
Mean time between licks in bursts0.52.94.11.7-1.61.7-1.7-1.7-1.7-1.71.61.6-1.6-1.60.7-1.42.02.0-2.0-2.0-2.02.01.4
Mean num. licks in bursts0.10.30.30.6-0.60.5-0.5-0.5-0.5-0.50.60.6-0.6-0.60.5-0.60.60.6-0.6-0.6-0.60.60.5
Cd content in liver1.31.52.4-1.11.1-1.11.11.11.11.1-1.1-1.11.11.1-1.61.3-1.2-1.21.21.21.2-1.2-1.6
Co content in liver4.75.56.3-2.42.4-2.42.42.42.42.4-2.4-2.42.42.4-1.12.1-2.5-2.52.52.52.5-2.5-1.7
Cu content in liver0.40.50.6-0.70.7-0.70.70.70.70.7-0.7-0.70.70.6-0.30.6-0.8-0.80.80.80.8-0.7-0.5
Fe content in liver1.31.62.01.4-1.41.4-1.4-1.4-1.4-1.41.41.4-1.4-1.40.9-1.31.11.1-1.1-1.1-1.11.10.9
K content in liver1.11.11.31.1-1.11.1-1.1-1.1-1.1-1.11.11.1-1.1-1.11.1-1.11.01.0-1.0-1.0-1.01.01.1
Mg content in liver2.52.72.91.7-1.71.7-1.7-1.7-1.7-1.71.71.7-1.7-1.71.5-1.71.61.6-1.6-1.6-1.61.61.6
Mn content in liver2.22.52.91.7-1.71.7-1.7-1.7-1.7-1.71.71.7-1.7-1.70.9-1.51.61.6-1.6-1.6-1.61.61.2
Na content in liver1.41.65.8-0.91.0-1.01.01.01.01.0-1.0-1.01.01.0-2.41.5-1.1-1.11.11.11.1-1.2-2.1
Rb content in liver0.10.10.60.1-0.10.2-0.2-0.2-0.2-0.20.10.1-0.2-0.20.8-0.30.00.0-0.0-0.0-0.00.10.5
Se content in liver0.91.01.21.1-1.11.1-1.1-1.1-1.1-1.11.11.0-1.0-1.1-1.1-0.41.01.0-1.0-1.0-1.01.0-0.4
Sr content in liver0.00.00.10.2-0.20.1-0.1-0.1-0.1-0.10.20.2-0.2-0.2-0.2-0.0-0.0-0.00.00.00.0-0.1-0.3
Zn content in liver0.10.10.20.4-0.40.4-0.4-0.4-0.4-0.40.40.4-0.4-0.4-0.4-0.20.20.2-0.2-0.2-0.20.2-0.3
Bone: minimum diameter0.30.52.0-0.50.5-0.50.50.50.50.5-0.5-0.50.50.5-1.40.7-0.7-0.70.70.70.7-0.7-1.3
Time in familiar zone, hab. session 10.00.00.1-0.20.2-0.10.10.10.10.1-0.2-0.20.20.20.3-0.0-0.2-0.20.20.20.2-0.20.1
Time in novel zone, hab. session 11.01.11.3-1.11.1-1.11.11.11.11.1-1.1-1.11.11.1-0.30.9-1.1-1.11.11.11.1-1.1-0.6
Total zone transitions, hab. session 10.20.31.2-0.50.5-0.60.60.60.60.6-0.5-0.50.50.5-1.10.6-0.4-0.40.40.40.4-0.4-0.9
Total locomotion distance, hab. session 10.10.11.00.1-0.1-0.00.00.00.00.00.10.1-0.1-0.1-1.00.20.10.1-0.1-0.1-0.10.0-0.7
Locomotion velocity, hab. session 10.20.21.60.4-0.40.3-0.3-0.3-0.3-0.30.40.4-0.3-0.4-1.30.10.40.4-0.4-0.4-0.40.3-0.7
Time in familiar zone, hab. session 21.61.82.2-1.51.5-1.51.51.51.51.5-1.4-1.41.41.50.20.9-1.4-1.41.41.41.4-1.4-0.4
Time in novel zone, hab. session 20.50.60.80.9-0.90.9-0.9-0.9-0.9-0.90.90.8-0.8-0.9-0.2-0.50.80.8-0.8-0.8-0.80.70.1
Total zone transitions, hab. session 21.41.84.5-1.31.3-1.31.31.31.31.3-1.3-1.31.31.3-2.11.6-1.1-1.11.11.11.1-1.1-1.7
Total locomotion distance, hab. session 20.30.41.6-0.50.5-0.60.60.60.60.6-0.5-0.50.50.5-1.20.8-0.4-0.40.40.40.4-0.4-0.9
Locomotion velocity, hab. session 20.70.93.0-0.80.8-0.90.90.90.90.9-0.8-0.90.90.8-1.71.2-0.7-0.70.70.70.7-0.7-1.4
Novel to familiar place preference ratio1.11.51.71.3-1.31.3-1.3-1.3-1.3-1.31.31.3-1.3-1.30.3-1.01.31.3-1.3-1.3-1.31.20.7
Novelty place preference0.91.11.31.1-1.11.2-1.2-1.2-1.2-1.21.11.1-1.1-1.10.3-0.91.11.1-1.1-1.1-1.11.10.6
Time in novel zone, NPP test0.50.60.70.8-0.80.8-0.8-0.8-0.8-0.80.80.8-0.8-0.80.1-0.60.80.8-0.8-0.8-0.80.80.4
Total zone transitions, NPP test0.20.20.40.5-0.50.4-0.4-0.4-0.4-0.40.50.5-0.5-0.5-0.6-0.10.60.6-0.6-0.6-0.60.6-0.1
Total locomotion distance, NPP test2.33.33.91.9-1.91.9-1.9-1.9-1.9-1.91.91.9-1.9-1.90.3-1.42.02.0-2.0-2.0-2.01.90.9
Locomotion velocity, NPP test2.23.23.91.9-1.91.8-1.8-1.8-1.8-1.81.91.9-1.9-1.90.3-1.42.02.0-2.0-2.0-2.01.90.9
Intraocular pressure0.60.91.50.8-0.80.9-0.9-0.9-0.9-0.90.80.8-0.8-0.80.4-0.81.21.2-1.2-1.2-1.21.20.9
Delta distance traveled before/after self-admin2.42.63.2-1.81.8-1.81.81.81.81.8-1.8-1.81.71.80.11.3-1.7-1.71.71.71.7-1.6-0.5
Delta ambulatory time before/after self-admin1.72.93.5-1.91.9-1.81.81.81.81.8-1.8-1.81.81.8-0.21.4-1.8-1.81.81.81.8-1.7-0.7
Parametrial fat weight1.63.84.22.1-2.12.1-2.1-2.1-2.1-2.12.02.0-2.0-2.01.5-2.01.91.9-1.9-1.9-1.91.91.6
Pavlov. Cond. lever latency0.00.00.4-0.00.00.0-0.0-0.0-0.0-0.00.00.0-0.0-0.00.7-0.2-0.1-0.10.10.10.1-0.10.4
Pavlov. Cond. magazine entry latency0.00.00.00.2-0.20.1-0.1-0.1-0.1-0.10.20.2-0.2-0.20.1-0.20.20.2-0.2-0.2-0.20.20.1
Pavlov. Cond. change in total contacts1.11.22.1-1.11.1-1.21.21.21.21.2-1.1-1.11.11.1-1.51.2-0.9-0.90.90.90.9-0.9-1.3
Pavlov. Cond. index score0.10.10.5-0.30.3-0.30.30.30.30.3-0.3-0.30.30.3-0.70.4-0.2-0.20.20.20.2-0.2-0.5
Pavlov. Cond. latency score0.00.10.4-0.20.2-0.20.20.20.20.2-0.2-0.20.20.2-0.60.3-0.1-0.10.10.10.1-0.1-0.5
Pavlov. Cond. lever contacts0.00.00.30.1-0.10.1-0.1-0.1-0.1-0.10.10.1-0.1-0.1-0.50.00.20.2-0.2-0.2-0.20.2-0.2
Pavlov. Cond. magazine entry number0.30.40.50.7-0.70.7-0.7-0.7-0.7-0.70.70.7-0.7-0.70.6-0.60.60.6-0.6-0.6-0.60.60.6
Pavlov. Cond. intertrial magazine entries0.10.10.60.4-0.40.4-0.4-0.4-0.4-0.40.30.3-0.3-0.4-0.80.00.20.2-0.2-0.2-0.20.2-0.5
Pavlov. Cond. lever-magazine prob. diff.0.20.20.7-0.50.5-0.50.50.50.50.5-0.5-0.50.50.5-0.80.5-0.4-0.40.40.40.4-0.4-0.7
Pavlov. Cond. response bias0.10.20.3-0.40.4-0.40.40.40.40.4-0.4-0.40.40.4-0.50.4-0.3-0.30.30.30.3-0.3-0.4
Pavlov. Cond. lever latency0.50.73.60.7-0.70.7-0.7-0.7-0.7-0.70.70.7-0.7-0.71.9-1.10.60.6-0.6-0.6-0.60.61.5
Pavlov. Cond. magazine entry latency0.10.10.50.3-0.30.3-0.3-0.3-0.3-0.30.30.3-0.3-0.3-0.70.00.30.3-0.3-0.3-0.30.3-0.3
Pavlov. Cond. change in total contacts0.81.93.8-1.31.3-1.31.31.31.31.3-1.3-1.41.41.4-2.01.6-1.2-1.21.21.21.2-1.3-1.7
Pavlov. Cond. index score0.40.73.3-0.70.7-0.60.60.60.60.6-0.7-0.70.70.7-1.81.1-0.6-0.60.60.60.6-0.6-1.4
Pavlov. Cond. latency score0.30.53.1-0.50.5-0.50.50.50.50.5-0.6-0.60.60.6-1.70.9-0.4-0.40.40.40.4-0.5-1.3
Pavlov. Cond. lever contacts0.30.43.0-0.40.4-0.40.40.40.40.4-0.5-0.50.50.5-1.70.9-0.3-0.30.30.30.3-0.4-1.3
Pavlov. Cond. magazine entry number0.00.10.3-0.20.2-0.20.20.20.20.2-0.2-0.20.20.20.6-0.1-0.3-0.30.30.30.3-0.20.3
Pavlov. Cond. intertrial magazine entries3.47.58.22.8-2.82.8-2.8-2.8-2.8-2.82.82.8-2.8-2.81.9-2.72.92.9-2.9-2.9-2.92.82.4
Pavlov. Cond. lever-magazine prob. diff.0.50.73.1-0.70.7-0.70.70.70.70.7-0.8-0.80.80.8-1.81.1-0.6-0.60.60.60.6-0.7-1.4
Pavlov. Cond. response bias0.30.53.3-0.50.5-0.50.50.50.50.5-0.5-0.50.50.5-1.80.9-0.4-0.40.40.40.4-0.5-1.3
Time in closed arm before self-admin1.11.82.2-1.51.5-1.41.41.41.41.4-1.4-1.41.41.5-0.61.3-1.4-1.41.41.41.4-1.4-0.8
Time in closed arm after self-admin0.00.00.0-0.20.2-0.20.20.20.20.2-0.2-0.20.20.2-0.10.2-0.2-0.20.20.20.2-0.2-0.1
Time in open arm before self-admin0.00.00.10.1-0.10.1-0.1-0.1-0.1-0.10.00.0-0.0-0.1-0.30.10.00.0-0.0-0.0-0.0-0.0-0.2
Time in open arm after self-admin0.00.00.10.2-0.20.2-0.2-0.2-0.2-0.20.20.2-0.2-0.2-0.2-0.10.20.2-0.2-0.2-0.20.2-0.0
Bone: periosteal estimation0.10.20.8-0.30.3-0.30.30.30.30.3-0.3-0.30.30.3-0.90.4-0.5-0.50.50.50.5-0.5-0.8
Bone: periosteal perimeter0.10.10.6-0.20.2-0.20.20.20.20.2-0.2-0.20.20.2-0.80.4-0.4-0.40.40.40.4-0.4-0.7
Bone: post-yield work0.20.31.00.4-0.40.4-0.4-0.4-0.4-0.40.40.5-0.5-0.41.0-0.70.50.5-0.5-0.5-0.50.50.9
Progressive ratio test 1 active lever presses0.10.10.5-0.30.3-0.30.30.30.30.3-0.3-0.30.30.30.7-0.0-0.2-0.20.20.20.2-0.20.4
Progressive ratio test 1 breakpoint0.10.20.4-0.40.4-0.40.40.40.40.4-0.4-0.40.40.40.70.1-0.3-0.30.30.30.3-0.30.3
Progressive ratio test 1 inactive lever presses0.51.31.71.1-1.11.1-1.1-1.1-1.1-1.11.11.1-1.1-1.11.3-1.21.11.1-1.1-1.1-1.11.11.3
Progressive ratio test 2 active lever presses0.10.10.60.2-0.20.2-0.2-0.2-0.2-0.20.20.2-0.2-0.20.7-0.40.20.2-0.2-0.2-0.20.20.6
Progressive ratio test 2 breakpoint0.00.10.30.1-0.10.1-0.1-0.1-0.1-0.10.20.2-0.2-0.10.6-0.30.20.2-0.2-0.2-0.20.20.4
Progressive ratio test 2 inactive lever presses0.10.40.50.7-0.70.6-0.6-0.6-0.6-0.60.70.7-0.7-0.60.6-0.70.70.7-0.7-0.7-0.70.70.7
Incentive Sensitization - Responses0.10.30.30.6-0.60.6-0.6-0.6-0.6-0.60.60.6-0.6-0.60.3-0.50.60.6-0.6-0.6-0.60.60.4
Incentive Sensitization - Breakpoint0.20.40.50.7-0.70.7-0.7-0.7-0.7-0.70.70.7-0.7-0.70.3-0.60.70.7-0.7-0.7-0.70.60.4
Sum of active levers in priming session hrs 5-60.20.20.80.3-0.30.3-0.3-0.3-0.3-0.30.30.4-0.4-0.30.9-0.50.40.4-0.4-0.4-0.40.40.7
Progressive ratio0.00.00.1-0.10.1-0.20.20.20.20.2-0.1-0.10.10.10.30.1-0.1-0.10.10.10.1-0.10.2
Food seeking constrained by brief footshock1.82.22.8-1.71.7-1.71.71.71.71.7-1.6-1.61.61.60.81.0-1.5-1.51.51.51.5-1.40.1
Seeking ratio, punishment vs. effort0.40.81.1-1.01.0-0.90.90.90.90.9-1.0-1.01.01.00.00.7-0.9-0.90.90.90.9-0.9-0.3
Retroperitoneal fat weight0.10.41.20.6-0.60.6-0.6-0.6-0.6-0.60.70.7-0.7-0.61.1-0.90.30.3-0.3-0.3-0.30.30.7
Reaction time number correct0.20.81.1-1.01.0-1.01.01.01.01.0-1.0-1.01.01.0-0.20.9-0.8-0.80.80.80.8-0.7-0.3
Reaction time mean minus median0.00.20.9-0.30.3-0.10.10.10.10.1-0.4-0.40.40.4-0.90.5-0.5-0.50.50.50.5-0.5-0.8
Reaction time mean minus median AUC0.00.10.3-0.20.2-0.00.00.00.00.0-0.3-0.30.30.3-0.60.3-0.3-0.30.30.30.3-0.3-0.5
Reaction time num false alarms0.10.10.4-0.40.4-0.20.20.20.20.2-0.4-0.40.40.4-0.60.4-0.1-0.10.10.10.1-0.1-0.3
Reaction time num false alarms AUC0.00.10.2-0.30.3-0.20.20.20.20.2-0.3-0.30.30.4-0.50.30.00.0-0.0-0.0-0.00.0-0.2
Reaction time trials correct on left0.20.81.1-1.01.0-1.01.01.01.01.0-1.0-1.01.01.0-0.20.9-0.8-0.80.80.80.8-0.7-0.3
Reaction time trials on left0.20.60.8-0.90.9-0.90.90.90.90.9-0.9-0.90.90.8-0.10.7-0.6-0.60.60.60.6-0.6-0.2
Reaction time mean0.10.10.4-0.40.4-0.30.30.30.30.3-0.4-0.40.40.4-0.60.5-0.3-0.30.30.30.3-0.3-0.5
Reaction time mean AUC0.10.40.7-0.60.6-0.50.50.50.50.5-0.6-0.60.60.6-0.90.7-0.5-0.50.50.50.5-0.6-0.7
Median of all reaction times0.10.10.2-0.40.4-0.30.30.30.30.3-0.4-0.40.40.4-0.30.4-0.2-0.20.20.20.2-0.2-0.2
Reaction time omissions1.72.83.01.6-1.61.7-1.7-1.7-1.7-1.71.61.6-1.6-1.61.3-1.71.71.7-1.7-1.7-1.71.71.6
Reaction time false alarm rate0.10.10.20.3-0.30.4-0.4-0.4-0.4-0.40.30.3-0.3-0.2-0.1-0.30.40.4-0.4-0.4-0.40.40.1
Reaction time premature initiation rate1.32.12.7-1.61.6-1.61.61.61.61.6-1.6-1.61.61.6-0.41.3-1.3-1.31.31.31.3-1.3-0.6
Reaction time premature initiations1.03.04.0-2.02.0-2.02.02.02.02.0-2.0-2.02.02.0-0.41.6-1.5-1.51.51.51.5-1.5-0.6
Std. dev. reaction times0.00.10.5-0.30.4-0.10.10.10.10.1-0.4-0.40.40.4-0.70.4-0.3-0.30.30.30.3-0.3-0.6
Reaction time trials completed0.20.60.8-0.90.9-0.90.90.90.90.9-0.9-0.90.90.8-0.10.7-0.6-0.60.60.60.6-0.6-0.2
Reaction time trials AUC0.10.50.7-0.90.9-0.80.80.80.80.8-0.8-0.80.80.8-0.10.7-0.6-0.60.60.60.6-0.6-0.2
Run reversals in cocaine runway, females2.63.03.41.8-1.81.7-1.7-1.7-1.7-1.71.81.8-1.8-1.71.3-1.91.81.8-1.8-1.8-1.81.81.5
Run reversals in cocaine runway, males1.82.02.0-1.41.4-1.41.41.41.41.4-1.4-1.41.41.4-1.21.4-1.4-1.41.41.41.4-1.4-1.3
Latency to leave start box in cocaine runway0.30.50.6-0.70.7-0.60.60.60.60.6-0.7-0.70.70.8-0.60.6-0.7-0.70.70.70.7-0.7-0.6
Latency to leave start box in cocaine runway, F1.21.51.7-1.31.3-1.21.21.21.21.2-1.3-1.31.31.3-1.11.1-1.3-1.31.31.31.3-1.3-1.2
Latency to leave start box in cocaine runway, M0.10.10.10.3-0.30.3-0.3-0.3-0.3-0.30.30.3-0.3-0.30.1-0.20.30.3-0.3-0.3-0.30.30.2
Std. dev. time between licks in bursts1.01.82.81.3-1.31.3-1.3-1.3-1.3-1.31.31.3-1.3-1.3-0.7-0.81.71.7-1.7-1.7-1.71.60.3
Total sessions with >9 infusions0.00.00.1-0.20.2-0.20.20.20.20.2-0.2-0.20.20.20.10.0-0.2-0.20.20.20.2-0.2-0.0
Short access day 1 total inactive lever presses0.10.10.20.4-0.40.4-0.4-0.4-0.4-0.40.40.4-0.4-0.4-0.4-0.20.30.3-0.3-0.3-0.30.3-0.2
Short access day 10 total inactive lever presses0.00.20.20.5-0.50.5-0.5-0.5-0.5-0.50.50.5-0.5-0.50.4-0.40.50.5-0.5-0.5-0.50.50.4
Short access day 1 total infusions0.00.10.1-0.30.3-0.30.30.30.30.3-0.3-0.20.20.30.40.0-0.2-0.20.20.20.2-0.20.2
Short access day 10 total infusions0.30.40.8-0.60.6-0.60.60.60.60.6-0.6-0.60.60.6-0.90.6-0.6-0.60.60.60.6-0.7-0.9
Short access total infusions0.00.10.1-0.20.2-0.20.20.20.20.2-0.2-0.20.20.2-0.20.2-0.2-0.20.20.20.2-0.2-0.2
Short access day 1 locomotion0.71.21.9-1.01.0-1.01.01.01.01.0-1.0-1.01.01.0-1.41.1-1.1-1.11.11.11.1-1.1-1.3
Short access day 10 total locomotion0.00.00.40.0-0.00.1-0.1-0.1-0.1-0.10.0-0.00.0-0.1-0.60.4-0.0-0.00.00.00.0-0.1-0.4
Short access total locomotion0.20.31.2-0.30.3-0.40.40.40.40.4-0.4-0.40.40.4-1.10.6-0.4-0.40.40.40.4-0.5-1.0
One hour access (0.3 mA shock)0.60.70.80.9-0.90.9-0.9-0.9-0.9-0.90.90.9-0.9-0.90.1-0.60.80.8-0.8-0.8-0.80.80.3
Compulsive drug intake0.40.60.80.8-0.80.9-0.9-0.9-0.9-0.90.80.8-0.8-0.9-0.2-0.40.80.8-0.8-0.8-0.80.70.1
One hour access (shock baseline)0.00.00.00.0-0.0-0.00.00.00.00.00.00.0-0.00.0-0.2-0.10.00.0-0.0-0.0-0.0-0.0-0.2
Social response proportion0.20.31.6-0.40.4-0.40.40.40.40.4-0.3-0.30.30.41.3-0.3-0.5-0.50.50.50.5-0.50.6
Social responses0.91.21.61.2-1.21.1-1.1-1.1-1.1-1.11.21.2-1.2-1.21.3-1.30.90.9-0.9-0.9-0.90.91.0
Social time0.20.30.40.7-0.70.6-0.6-0.6-0.6-0.60.60.6-0.6-0.6-0.5-0.50.50.5-0.5-0.5-0.50.4-0.3
Soleus weight1.03.03.8-1.91.9-1.91.91.91.91.9-1.9-1.91.91.9-0.91.7-1.6-1.61.61.61.6-1.6-1.1
Bone: stiffness0.71.21.5-1.11.1-1.11.11.11.11.1-1.0-1.01.01.1-1.01.0-1.2-1.21.21.21.2-1.2-1.2
Tibialis anterior weight8.027.528.5-5.35.3-5.35.35.35.35.3-5.3-5.35.35.3-4.35.3-5.3-5.35.35.35.3-5.3-4.8
Time to tail flick, vehicle, before self-admin0.91.11.21.0-1.01.0-1.0-1.0-1.0-1.01.01.0-1.0-1.01.0-1.11.11.1-1.1-1.1-1.11.11.1
Time to tail flick, vehicle, after self-admin0.81.62.2-1.41.4-1.51.51.51.51.5-1.4-1.41.31.40.30.9-1.3-1.31.31.31.3-1.2-0.2
Time to tail flick, test, before self-admin2.52.83.21.8-1.81.8-1.8-1.8-1.8-1.81.81.8-1.8-1.80.8-1.61.71.7-1.7-1.7-1.71.71.1
Time to tail flick, test, after self-admin2.72.85.41.5-1.51.6-1.6-1.6-1.6-1.61.61.6-1.6-1.62.3-1.81.61.6-1.6-1.6-1.61.72.2
Delta time to tail flick, vehicle, before/after SA0.30.30.4-0.60.6-0.60.60.60.60.6-0.6-0.50.50.50.60.2-0.5-0.50.50.50.5-0.40.2
Delta time to tail flick, test, before/after SA0.20.33.00.0-0.00.1-0.1-0.1-0.1-0.10.10.1-0.1-0.11.7-0.50.20.2-0.2-0.2-0.20.31.3
Tibia length0.92.63.51.9-1.91.8-1.8-1.8-1.8-1.81.81.8-1.8-1.8-0.9-1.21.51.5-1.5-1.5-1.51.4-0.3
Ambulatory time before self-admin0.20.51.7-0.60.6-0.60.60.60.60.6-0.6-0.60.60.6-1.30.8-0.6-0.60.60.60.6-0.7-1.1
Ambulatory time after self-admin3.75.96.2-2.52.5-2.52.52.52.52.5-2.5-2.52.52.5-1.82.4-2.5-2.52.52.52.5-2.5-2.1
Bone: tissue strength0.00.00.10.2-0.20.2-0.2-0.2-0.2-0.20.20.2-0.2-0.2-0.1-0.10.00.0-0.0-0.0-0.0-0.0-0.2
Total heroin consumption0.60.81.0-0.80.8-0.90.90.90.90.9-0.8-0.80.80.8-1.00.8-0.8-0.80.80.80.8-0.9-1.0
Bone: trabecular number1.73.33.61.9-1.91.9-1.9-1.9-1.9-1.91.91.9-1.9-1.91.2-1.81.81.8-1.8-1.8-1.81.81.4
Bone: trabecular spacing2.02.93.1-1.71.7-1.81.81.81.81.8-1.7-1.71.71.7-1.21.7-1.8-1.81.81.81.8-1.7-1.4
Bone: trabecular thickness1.01.31.51.2-1.21.2-1.2-1.2-1.2-1.21.21.2-1.2-1.20.4-1.01.21.2-1.2-1.2-1.21.20.8
Bone: trabecular tissue density1.12.02.2-1.41.4-1.41.41.41.41.4-1.4-1.41.41.4-1.51.5-1.4-1.41.41.41.4-1.4-1.5
Water consumed over 24 hours0.81.61.8-1.31.3-1.31.31.31.31.3-1.3-1.31.31.3-1.31.3-1.3-1.31.31.31.3-1.3-1.3
Number of responses in last shaping day0.50.60.7-0.80.8-0.80.80.80.80.8-0.8-0.80.80.8-0.60.6-0.8-0.80.80.80.8-0.8-0.7