Hub : Genes

Ccdc92b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL mRNA stability Ccdc92b 0.03 0.03 8.6e-04 0.03 0.03 0.03 0.03 2.4e-04 6.9e-04 4.6e-04 2.0e-04
2 Brain mRNA stability Ccdc92b 0.06 0.04 8.9e-05 0.05 0.05 0.04 0.04 3.0e-05 4.3e-05 9.9e-05 5.0e-05
3 Brain gene expression Ccdc92b 0.04 0.03 5.8e-04 0.03 0.04 0.03 0.03 1.1e-03 2.5e-04 4.5e-04 9.9e-04
4 Adipose mRNA stability Ccdc92b 0.08 0.05 4.4e-07 0.02 0.03 0.01 0.02 1.7e-03 3.1e-04 1.7e-02 1.2e-03
5 OFC mRNA stability Ccdc92b 0.14 0.1 5.8e-03 0.09 0.11 0.07 0.09 4.0e-03 1.8e-03 1.0e-02 3.3e-03
6 BLA gene expression Ccdc92b 0.09 0.06 2.9e-04 0.04 0.05 0.04 0.04 1.9e-03 9.5e-04 4.9e-03 2.2e-03
7 Adipose gene expression Ccdc92b 0.18 0.09 1.9e-15 0.07 0.11 0.12 0.11 1.2e-08 3.3e-12 7.2e-13 3.1e-12
8 PL gene expression Ccdc92b 0.02 0.01 8.7e-03 0 0 0 0 1.2e-01 2.0e-01 1.1e-01 3.3e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bone: apparent density3.15.18.22.9-2.6-2.02.81.6-1.5-2.71.4
Area under the delay curve0.70.81.6-1.30.90.8-0.9-0.60.61.0-0.7
BMI with tail1.23.94.72.1-2.0-2.22.02.1-2.0-1.61.9
BMI without tail0.20.31.10.5-0.5-0.41.00.3-0.2-0.80.2
Body weight0.72.98.21.8-1.9-0.52.8-0.00.1-2.9-0.3
Weight adjusted by age1.82.03.61.7-1.9-1.41.41.4-1.3-1.01.0
Bone surface3.25.77.92.8-2.6-2.42.62.1-2.0-2.42.0
Bone volume3.66.18.52.9-2.7-2.52.72.2-2.2-2.42.0
Breakpoint value in progressive ratio session0.50.61.80.7-0.8-0.11.3-0.10.2-1.3-0.4
Number of licking bursts0.20.20.5-0.40.30.3-0.7-0.20.20.7-0.2
Context. condit. distance diff. score1.11.32.61.5-1.6-0.81.50.5-0.5-1.50.3
Locomotion velocity, session 11.51.64.51.4-1.4-0.42.10.00.0-2.1-0.2
Locomotion distance, session 10.50.61.31.1-0.9-0.71.00.6-0.6-0.80.5
Locomotion velocity, session 20.50.61.21.0-1.0-0.51.10.3-0.3-1.00.2
Locomotion distance, session 21.42.03.11.8-1.7-1.31.71.1-1.1-1.51.0
Locomotion velocity, session 35.36.19.6-2.93.12.4-2.6-2.12.12.3-2.0
Locomotion distance, session 30.10.10.2-0.10.3-0.3-0.10.4-0.30.20.4
Stereotopy head waving bouts, day 30.50.51.2-0.20.40.9-0.1-1.11.0-0.1-1.0
Stereotopy head waving duration, day 30.20.20.6-0.20.30.4-0.7-0.40.30.8-0.2
Locomotion velocity, session 71.51.72.31.2-1.1-1.51.21.5-1.4-0.91.3
Locomotion distance, session 72.93.74.61.9-2.2-2.11.82.1-2.0-1.51.8
Stereotopy head waving bouts, day 70.50.61.41.2-0.9-0.31.0-0.0-0.1-1.10.1
Stereotopy head waving duration, day 70.70.81.81.3-1.0-0.51.20.2-0.2-1.30.3
Locomotion velocity, session 80.30.40.70.9-0.8-0.60.70.4-0.5-0.60.5
Locomotion distance, session 81.82.65.12.0-2.3-1.02.20.6-0.6-2.20.3
Degree of sensitization distance1.31.42.91.3-1.7-0.91.40.8-0.8-1.40.5
Degree of sensitization stereotypy0.70.82.11.2-1.0-0.31.3-0.10.0-1.4-0.1
Conditioned locomotion0.50.61.3-0.81.00.6-1.1-0.50.41.1-0.3
Cocaine response after cond. corrected0.20.20.40.2-0.20.50.3-0.60.6-0.4-0.7
Cocaine response after cond. not corrected0.20.30.60.5-0.30.30.7-0.40.4-0.8-0.5
Cocaine response before conditioning0.70.91.61.1-0.8-0.81.30.7-0.6-1.20.6
Saline control response1.11.41.71.3-1.3-1.31.01.3-1.2-0.71.2
Bone: connectivity density4.77.411.73.4-3.2-2.53.22.0-2.0-3.11.9
Bone: cortical apparent density0.20.20.7-0.0-0.1-0.3-0.60.5-0.50.80.4
Bone: cortical area0.91.42.9-1.71.40.7-1.7-0.40.41.6-0.4
Bone: cortical porosity0.10.20.30.4-0.6-0.30.60.2-0.2-0.60.1
Bone: cortical porosity0.00.00.10.0-0.20.00.2-0.00.0-0.2-0.1
Bone: cortical thickness4.87.812.3-3.53.22.7-3.1-2.32.22.7-2.2
Bone: cortical thickness1.72.02.6-1.61.51.6-1.2-1.51.50.7-1.5
Bone: cortical tissue density0.10.20.40.1-0.2-0.3-0.50.5-0.50.70.4
Condit. Reinf. active minus inactive responses0.50.50.7-0.70.80.8-0.4-0.80.80.3-0.9
Condit. Reinf. active-inactive response ratio3.84.15.3-2.32.22.3-1.4-2.22.20.9-2.3
Condit. Reinf. active responses0.20.30.50.7-0.7-0.50.60.5-0.5-0.50.4
Condit. Reinf. inactive responses5.66.78.73.0-2.9-2.91.72.8-2.8-1.22.7
Incentive salience index mean0.60.71.2-0.70.91.0-0.2-1.01.0-0.0-1.1
Condit. Reinf. lever presses0.50.71.1-0.00.30.70.7-1.01.0-1.0-1.1
Condit. Reinf. active minus inactive responses1.01.21.81.2-1.3-1.21.01.2-1.1-0.80.9
Condit. Reinf. active-inactive response ratio0.00.00.1-0.0-0.20.10.1-0.10.2-0.1-0.3
Condit. Reinf. active responses2.53.54.71.9-2.0-2.21.42.2-2.1-1.02.0
Condit. Reinf. inactive responses4.85.98.72.3-2.2-2.91.52.9-2.9-0.93.0
Condit. Reinf. lever presses0.50.71.60.3-0.2-0.9-0.41.1-1.10.61.3
Condit. Reinf. lever reinforcers received2.63.75.21.9-1.9-2.21.32.3-2.2-0.92.1
Conditioned reinforcement - actives3.23.24.21.9-2.0-2.01.52.0-1.9-1.21.7
Conditioned reinforcement - inactives1.61.82.91.3-1.7-1.51.11.5-1.5-0.61.3
Conditioned locomotion0.10.10.3-0.20.3-0.1-0.50.3-0.30.50.3
Patch foraging indifference point 0 sec0.10.10.30.3-0.2-0.30.50.2-0.2-0.50.4
Patch foraging indifference point AUC0.50.61.00.2-0.4-0.8-0.41.0-1.00.70.9
Delay disc. indifference point, 0s delay0.10.10.20.2-0.2-0.40.40.4-0.4-0.30.3
Delay disc. indifference point, 16s delay0.20.20.7-0.5-0.3-0.1-0.50.4-0.30.8-0.0
Delay disc. indifference point, 2s delay0.60.71.0-1.00.80.8-1.0-0.60.61.0-0.7
Delay disc. indifference point, 24s delay0.00.00.1-0.30.0-0.0-0.20.2-0.10.4-0.1
Delay disc. indifference point, 4s delay0.30.30.6-0.70.30.7-0.4-0.60.60.4-0.8
Delay disc. indifference point, 8s delay0.40.40.8-0.90.60.6-0.6-0.50.50.6-0.6
Indifference point function ln k0.30.41.30.7-0.6-0.21.2-0.00.0-1.10.1
Indifference point function log k0.30.41.30.7-0.6-0.21.2-0.00.0-1.10.1
Patch foraging total patch changes 0 sec0.10.20.30.4-0.2-0.40.50.3-0.3-0.40.5
Patch foraging total patch changes 12 sec0.70.91.6-1.11.30.9-0.9-0.90.90.9-0.7
Patch foraging total patch changes 18 sec0.30.40.7-0.80.70.6-0.8-0.50.50.7-0.4
Patch foraging total patch changes 24 sec0.40.51.2-0.91.00.5-1.1-0.30.31.1-0.2
Patch foraging total patch changes 6 sec0.20.20.5-0.20.2-0.4-0.50.5-0.50.60.7
Patch foraging time to switch 0 sec2.03.14.4-1.51.82.1-1.2-2.12.00.6-2.0
Patch foraging water rate 0 sec0.60.91.70.7-0.8-1.20.41.2-1.2-0.01.3
Patch foraging water rate 12 sec0.10.20.60.2-0.8-0.30.50.3-0.3-0.30.1
Patch foraging water rate 18 sec2.83.85.62.2-2.4-2.02.31.7-1.6-1.91.5
Patch foraging water rate 24 sec0.30.40.70.5-0.4-0.80.30.8-0.8-0.10.8
Patch foraging water rate 6 sec0.10.10.4-0.20.0-0.3-0.40.4-0.40.60.4
Seeking ratio, delayed vs. immediate footshock0.60.72.4-1.00.70.1-1.30.1-0.21.60.2
Distance traveled before self-admin1.11.22.8-1.21.20.8-1.5-0.50.51.7-0.4
Distance traveled after self-admin0.10.10.1-0.30.10.3-0.1-0.20.20.2-0.4
Extensor digitorum longus weight5.019.729.05.4-4.9-4.64.44.1-4.0-3.84.0
Bone: elastic displacement0.30.31.0-0.40.5-0.0-0.90.2-0.21.00.3
Bone: elastic work4.96.310.1-3.23.22.4-2.8-2.02.02.4-1.8
Bone: endosteal estimation0.30.71.10.7-0.8-1.00.41.0-1.0-0.11.0
Bone: endosteal perimeter2.04.26.11.9-2.0-2.41.32.5-2.4-0.72.4
Epididymis fat weight3.17.313.43.2-3.6-2.13.71.6-1.5-3.41.1
Delta time in closed arm before/after self-admin0.10.10.30.1-0.2-0.3-0.30.3-0.30.50.4
Delta time in open arm before/after self-admin0.40.41.30.8-0.5-0.40.90.3-0.3-1.20.1
Diff in mean of infusions in LGA sessions0.40.40.70.1-0.10.50.7-0.70.7-0.9-0.8
Delay discount exponential model param0.80.91.81.3-0.9-0.90.90.7-0.8-0.90.9
Extinction: sum of active levers before priming2.92.94.72.0-2.2-1.52.21.3-1.2-1.81.0
Active lever presses in extinction session 61.41.42.31.4-1.2-1.11.50.9-0.8-1.50.8
Bone: final force1.52.44.2-1.92.01.7-0.9-1.61.70.4-1.5
Bone: final moment1.22.03.8-1.81.91.5-0.9-1.41.50.5-1.3
Food consumed during 24 hour testing period0.20.30.60.5-0.5-0.50.70.4-0.3-0.80.4
Glucose1.82.85.6-2.21.91.2-2.4-0.70.72.4-0.6
Heart weight0.10.10.30.2-0.40.00.5-0.10.1-0.6-0.1
Delay discount hyperbolic model param0.70.81.51.2-0.8-0.80.90.6-0.7-0.90.8
Intermittent access intake day 1-15 change1.71.73.80.6-0.4-1.5-0.31.8-1.80.82.0
Intermittent access intake escalation1.31.22.20.10.1-1.1-0.91.4-1.41.31.5
Intermittent access intake escalation 21.11.03.2-0.60.8-0.3-1.50.7-0.71.80.9
Intermitt. access day 1 inactive lever presses1.11.23.2-1.70.90.5-1.5-0.20.21.8-0.3
Intermitt. access day 15 inactive lever presses0.20.30.70.1-0.7-0.4-0.20.5-0.50.80.3
Intermitt. access escalation Index2.52.24.6-0.00.51.60.6-1.91.9-1.4-2.1
Intermittent access day 1 total infusions1.11.32.11.2-1.4-1.21.21.1-1.1-0.90.9
Intermittent access day 15 total infusions2.83.25.51.5-1.4-2.20.62.3-2.3-0.12.3
Intermittent access terminal intake (last 3 days)2.52.73.51.7-1.7-1.91.31.8-1.8-0.91.7
Intermittent access total infusions1.71.93.01.3-1.4-1.70.81.7-1.7-0.31.6
Intermittent access day 1 locomotion0.10.10.3-0.60.20.2-0.1-0.10.10.3-0.3
Intermittent access day 15 total locomotion0.50.50.9-0.1-0.1-0.7-0.51.0-0.90.80.9
Intermittent access total locomotion0.10.10.30.0-0.1-0.40.00.5-0.50.20.4
Intermittent access standard deviation3.23.46.80.7-0.9-2.2-0.42.5-2.51.22.6
Left kidney weight3.39.312.6-3.63.03.4-2.6-3.13.12.2-3.2
Right kidney weight2.98.010.3-3.22.73.2-2.2-3.03.01.8-3.1
Cocaine induced anxiety0.60.71.30.3-0.5-1.0-0.21.1-1.10.51.2
Post-drug Anxiety0.20.30.40.5-0.6-0.60.30.6-0.6-0.20.6
Baseline Anxiety0.10.10.30.10.10.40.1-0.40.4-0.3-0.5
Tail length2.16.212.5-1.21.02.90.9-3.33.4-1.7-3.5
Length with tail0.93.46.5-0.30.22.01.2-2.42.5-1.8-2.5
Length without tail0.51.23.61.2-1.2-0.11.6-0.30.3-1.9-0.4
Times rat made contact with spout1.92.23.1-1.81.81.6-1.0-1.51.60.7-1.5
Lifetime Intake1.82.03.21.3-1.4-1.70.81.8-1.7-0.31.7
Liver weight, left1.21.94.3-0.80.41.60.3-1.81.8-0.7-2.1
Liver weight, right0.50.81.50.1-0.60.80.9-1.01.0-1.2-1.2
Locomotor activity0.20.41.00.5-1.0-0.60.50.7-0.7-0.30.4
Locomotor testing distance0.00.10.10.2-0.3-0.30.00.3-0.3-0.00.3
Locomotor testing rearing0.91.32.21.1-1.1-1.40.41.5-1.5-0.31.4
Locomotion in novel chamber1.72.14.9-0.40.4-1.1-1.61.5-1.62.21.7
Locomotion in novel chamber post-restriction0.20.20.60.4-0.1-0.60.20.5-0.5-0.10.8
Fecal boli incidents, locomotor time 10.10.10.3-0.30.30.40.0-0.50.5-0.2-0.3
Change in fecal boli incidents, locomotor task0.50.50.7-0.80.80.8-0.6-0.80.80.4-0.8
Time >=10cm from walls, locomotor time 10.10.10.30.20.0-0.30.10.3-0.3-0.10.5
Bouts of movement, locomotor time 10.10.10.40.3-0.3-0.30.50.2-0.2-0.60.3
Total resting periods, locomotor time 10.20.20.20.4-0.4-0.40.50.3-0.3-0.50.4
Rest time, locomotor task time 10.20.20.40.2-0.3-0.5-0.20.5-0.60.30.6
Distance moved, locomotor task time 10.20.20.30.4-0.4-0.50.30.5-0.5-0.10.5
Vertical activity count, locomotor time 10.50.60.70.8-0.6-0.90.80.8-0.8-0.70.8
Time >=10cm from walls, locomotor time 20.50.61.2-1.11.00.6-0.8-0.40.50.8-0.4
Bouts of movement, locomotor time 20.00.00.1-0.4-0.00.2-0.1-0.10.20.0-0.3
Total resting periods, locomotor time 20.00.00.1-0.1-0.2-0.10.30.1-0.0-0.3-0.0
Rest time, locomotor task time 20.40.51.20.6-1.1-0.80.30.8-0.8-0.20.6
Distance moved, locomotor task time 20.20.20.50.20.0-0.5-0.30.6-0.60.40.7
Vertical activity count, locomotor time 20.50.51.0-0.71.00.7-0.6-0.80.70.5-0.5
Light reinforcement 10.10.10.30.4-0.6-0.30.20.3-0.4-0.20.3
Light reinforcement 22.53.35.2-2.31.81.9-1.9-1.81.71.6-1.6
Bone: marrow area0.30.61.00.7-0.8-0.90.41.0-1.0-0.10.9
Bone: maximum diameter0.71.22.50.6-0.7-1.3-0.01.5-1.50.31.6
Bone: maximum force1.42.43.9-1.92.01.6-1.1-1.51.60.7-1.4
Bone: maximum moment1.11.93.4-1.81.81.4-1.1-1.31.30.8-1.2
Mean time between licks in bursts0.40.61.4-0.30.30.90.2-1.01.0-0.4-1.2
Mean num. licks in bursts0.50.61.0-0.81.00.8-0.0-0.90.9-0.2-0.9
Cd content in liver1.71.94.11.7-2.0-1.31.31.2-1.2-1.01.0
Co content in liver0.00.10.2-0.40.3-0.0-0.30.1-0.10.30.0
Cu content in liver1.11.42.2-1.41.51.2-0.9-1.01.10.9-1.2
Fe content in liver0.50.61.4-0.30.10.90.3-1.11.1-0.6-1.2
K content in liver2.12.13.4-1.31.51.7-0.3-1.81.8-0.1-1.8
Mg content in liver0.10.10.1-0.10.4-0.2-0.20.3-0.30.30.4
Mn content in liver0.10.10.10.40.1-0.20.30.1-0.1-0.30.3
Na content in liver2.93.14.5-2.12.01.8-1.7-1.61.61.6-1.5
Rb content in liver2.12.63.41.7-1.6-1.81.31.8-1.7-1.01.7
Se content in liver1.21.52.3-1.41.51.2-1.2-1.11.11.1-1.1
Sr content in liver0.50.40.80.9-0.7-0.60.80.4-0.4-0.80.4
Zn content in liver0.60.71.10.8-0.6-1.00.51.1-1.0-0.31.0
Bone: minimum diameter0.50.91.9-1.40.71.0-1.0-0.80.80.9-1.0
Time in familiar zone, hab. session 11.81.73.01.3-1.1-1.50.61.5-1.6-0.31.7
Time in novel zone, hab. session 11.21.22.1-1.10.81.3-0.6-1.31.30.3-1.5
Total zone transitions, hab. session 13.04.25.52.3-2.3-2.31.52.2-2.2-1.02.1
Total locomotion distance, hab. session 10.81.22.01.3-1.4-1.11.01.0-1.0-0.71.0
Locomotion velocity, hab. session 10.81.11.71.3-1.3-1.10.91.0-1.0-0.61.1
Time in familiar zone, hab. session 22.22.33.31.8-1.7-1.61.41.5-1.5-1.11.5
Time in novel zone, hab. session 25.15.17.4-2.72.52.4-2.1-2.12.11.8-2.1
Total zone transitions, hab. session 20.91.22.21.5-1.3-0.91.30.7-0.7-1.10.7
Total locomotion distance, hab. session 20.10.10.10.20.10.30.2-0.40.4-0.2-0.3
Locomotion velocity, hab. session 20.10.10.20.10.10.30.1-0.40.4-0.1-0.3
Novel to familiar place preference ratio0.30.30.6-0.20.3-0.6-0.30.8-0.70.40.8
Novelty place preference0.10.10.2-0.20.3-0.3-0.20.4-0.30.20.4
Time in novel zone, NPP test0.10.10.20.00.0-0.40.10.5-0.4-0.10.5
Total zone transitions, NPP test1.62.33.51.9-1.8-1.61.31.5-1.5-0.91.4
Total locomotion distance, NPP test0.60.81.31.0-1.0-1.10.31.1-1.10.11.0
Locomotion velocity, NPP test0.40.61.10.6-0.6-0.9-0.21.0-1.10.61.0
Intraocular pressure2.23.15.71.2-1.4-2.10.22.4-2.40.32.3
Delta distance traveled before/after self-admin0.80.82.80.9-0.9-0.31.5-0.00.1-1.7-0.2
Delta ambulatory time before/after self-admin0.60.62.10.7-0.7-0.11.3-0.20.2-1.5-0.3
Parametrial fat weight3.67.021.13.1-2.7-1.14.10.3-0.2-4.6-0.0
Pavlov. Cond. lever latency0.50.61.00.7-0.6-0.90.21.0-1.00.11.0
Pavlov. Cond. magazine entry latency0.30.40.7-0.10.20.60.5-0.80.8-0.7-0.8
Pavlov. Cond. change in total contacts0.60.60.7-0.80.80.8-0.8-0.80.70.7-0.8
Pavlov. Cond. index score0.50.71.3-0.30.40.90.4-1.11.1-0.7-1.1
Pavlov. Cond. latency score0.81.01.9-0.50.51.20.4-1.41.4-0.7-1.4
Pavlov. Cond. lever contacts0.40.50.9-0.60.50.8-0.1-0.90.9-0.1-0.9
Pavlov. Cond. magazine entry number0.10.10.2-0.0-0.1-0.4-0.30.5-0.50.30.5
Pavlov. Cond. intertrial magazine entries1.31.62.51.2-1.3-1.50.41.6-1.60.01.5
Pavlov. Cond. lever-magazine prob. diff.0.40.50.9-0.20.40.80.4-1.01.0-0.6-0.9
Pavlov. Cond. response bias0.20.20.4-0.00.10.50.3-0.60.6-0.5-0.6
Pavlov. Cond. lever latency0.40.51.80.7-0.4-0.11.2-0.20.3-1.3-0.3
Pavlov. Cond. magazine entry latency1.11.31.6-1.31.21.3-1.1-1.21.10.8-1.2
Pavlov. Cond. change in total contacts0.50.61.2-1.11.00.6-1.0-0.40.41.0-0.3
Pavlov. Cond. index score0.60.72.1-1.00.80.4-1.4-0.10.11.5-0.0
Pavlov. Cond. latency score0.81.02.7-1.10.90.5-1.6-0.10.11.6-0.0
Pavlov. Cond. lever contacts0.30.41.1-0.80.50.5-1.0-0.30.21.0-0.2
Pavlov. Cond. magazine entry number1.11.42.11.4-1.4-1.21.31.0-1.0-1.10.9
Pavlov. Cond. intertrial magazine entries2.22.94.12.0-2.0-1.81.81.6-1.5-1.51.3
Pavlov. Cond. lever-magazine prob. diff.0.50.71.9-1.00.70.4-1.4-0.10.11.4-0.0
Pavlov. Cond. response bias0.50.71.5-1.10.80.7-1.2-0.50.51.1-0.5
Time in closed arm before self-admin0.70.82.60.7-0.30.31.4-0.60.7-1.6-0.6
Time in closed arm after self-admin0.20.20.4-0.50.30.6-0.1-0.70.70.2-0.5
Time in open arm before self-admin2.22.46.5-2.01.30.9-2.3-0.40.42.6-0.5
Time in open arm after self-admin0.40.41.1-0.50.4-0.1-1.00.5-0.51.10.2
Bone: periosteal estimation0.10.20.7-0.70.40.1-0.70.2-0.10.80.1
Bone: periosteal perimeter0.40.61.30.2-0.4-0.9-0.11.1-1.10.41.1
Bone: post-yield work0.10.20.50.2-0.20.20.6-0.40.4-0.7-0.4
Progressive ratio test 1 active lever presses1.51.62.71.1-1.6-1.41.31.3-1.2-0.81.0
Progressive ratio test 1 breakpoint2.22.34.21.4-2.0-1.61.81.4-1.3-1.21.1
Progressive ratio test 1 inactive lever presses0.20.20.6-0.5-0.0-0.3-0.20.5-0.40.80.3
Progressive ratio test 2 active lever presses2.12.33.51.2-1.9-1.81.21.8-1.7-0.41.5
Progressive ratio test 2 breakpoint2.12.43.51.2-1.9-1.81.21.9-1.8-0.31.6
Progressive ratio test 2 inactive lever presses1.51.72.81.0-1.5-1.60.81.7-1.60.11.4
Incentive Sensitization - Responses1.31.32.40.8-1.5-1.30.91.4-1.30.01.1
Incentive Sensitization - Breakpoint1.01.01.80.6-1.4-1.20.81.2-1.10.10.9
Sum of active levers in priming session hrs 5-61.51.43.61.3-1.5-0.81.90.6-0.5-1.70.1
Progressive ratio0.40.51.20.5-0.4-0.90.40.8-0.8-0.11.1
Food seeking constrained by brief footshock0.20.20.3-0.40.60.4-0.5-0.40.40.4-0.3
Seeking ratio, punishment vs. effort1.01.21.9-1.01.01.3-0.9-1.21.20.6-1.4
Retroperitoneal fat weight0.00.00.20.2-0.5-0.1-0.20.2-0.20.20.1
Reaction time number correct0.00.00.10.0-0.1-0.10.30.1-0.1-0.30.0
Reaction time mean minus median0.10.10.3-0.00.2-0.2-0.50.2-0.30.50.4
Reaction time mean minus median AUC0.91.11.91.1-0.9-1.30.51.2-1.3-0.41.4
Reaction time num false alarms1.11.52.90.8-0.8-1.5-0.11.6-1.70.51.7
Reaction time num false alarms AUC0.91.32.50.7-0.6-1.4-0.11.5-1.50.51.6
Reaction time trials correct on left0.00.00.10.0-0.1-0.10.30.1-0.1-0.30.0
Reaction time trials on left0.00.00.10.0-0.1-0.20.30.2-0.1-0.20.1
Reaction time mean0.10.20.4-0.40.40.5-0.6-0.40.30.4-0.4
Reaction time mean AUC0.20.30.9-0.50.50.3-0.9-0.20.20.8-0.1
Median of all reaction times0.30.40.6-0.60.50.7-0.7-0.60.50.5-0.6
Reaction time omissions0.10.10.4-0.30.70.3-0.4-0.30.20.2-0.2
Reaction time false alarm rate0.71.02.00.7-0.6-1.2-0.11.3-1.30.51.4
Reaction time premature initiation rate0.50.71.30.9-1.1-0.71.10.5-0.5-0.80.5
Reaction time premature initiations0.60.91.51.0-1.2-0.91.20.7-0.7-0.90.6
Std. dev. reaction times0.10.10.4-0.20.50.0-0.60.0-0.10.60.2
Reaction time trials completed0.00.00.10.0-0.1-0.20.30.2-0.1-0.20.1
Reaction time trials AUC0.00.00.10.0-0.1-0.20.20.2-0.2-0.20.1
Run reversals in cocaine runway, females0.20.20.40.1-0.2-0.4-0.20.4-0.50.60.6
Run reversals in cocaine runway, males1.11.01.90.8-0.6-1.2-0.01.4-1.40.41.3
Latency to leave start box in cocaine runway0.40.50.8-0.70.90.8-0.4-0.80.80.2-0.7
Latency to leave start box in cocaine runway, F1.21.32.3-0.91.21.4-0.3-1.51.50.0-1.3
Latency to leave start box in cocaine runway, M0.00.00.00.00.1-0.00.10.0-0.0-0.20.0
Std. dev. time between licks in bursts0.20.30.50.7-0.6-0.60.50.5-0.5-0.50.5
Total sessions with >9 infusions0.30.30.40.5-0.6-0.70.60.6-0.6-0.50.5
Short access day 1 total inactive lever presses0.10.10.30.3-0.3-0.30.50.2-0.2-0.40.2
Short access day 10 total inactive lever presses0.40.50.7-0.80.70.8-0.2-0.80.80.2-0.8
Short access day 1 total infusions1.01.12.30.3-0.6-1.3-0.01.4-1.40.61.5
Short access day 10 total infusions2.83.14.81.5-1.9-2.11.22.2-2.1-0.61.9
Short access total infusions1.51.73.01.0-1.1-1.60.51.7-1.70.01.7
Short access day 1 locomotion0.40.40.9-0.1-0.1-0.7-0.20.9-0.90.70.8
Short access day 10 total locomotion0.20.20.7-0.70.50.1-0.50.1-0.00.8-0.0
Short access total locomotion0.30.30.6-0.20.0-0.6-0.20.8-0.70.60.7
One hour access (0.3 mA shock)3.13.64.91.9-2.0-2.21.42.2-2.1-0.72.1
Compulsive drug intake1.21.22.6-0.40.71.4-0.1-1.61.6-0.3-1.4
One hour access (shock baseline)3.33.86.31.6-1.9-2.41.12.5-2.4-0.42.3
Social response proportion1.41.53.60.3-0.10.81.5-1.21.3-1.9-1.3
Social responses0.70.93.31.0-0.7-0.21.6-0.20.2-1.8-0.3
Social time1.01.34.71.4-0.7-0.21.7-0.30.3-2.2-0.1
Soleus weight1.95.414.22.7-2.7-1.13.60.5-0.4-3.80.2
Bone: stiffness0.40.62.10.3-0.30.31.2-0.50.6-1.4-0.6
Tibialis anterior weight7.224.737.26.1-5.7-4.85.74.0-4.0-5.23.8
Time to tail flick, vehicle, before self-admin4.04.17.12.6-2.3-1.62.71.2-1.2-2.71.0
Time to tail flick, vehicle, after self-admin1.11.21.71.3-1.0-1.20.81.1-1.1-0.61.3
Time to tail flick, test, before self-admin0.20.20.50.40.30.30.4-0.70.6-0.7-0.2
Time to tail flick, test, after self-admin0.20.20.40.20.10.50.3-0.60.6-0.5-0.6
Delta time to tail flick, vehicle, before/after SA0.60.61.7-0.71.00.1-1.30.1-0.21.30.5
Delta time to tail flick, test, before/after SA0.60.50.90.6-0.8-0.80.31.0-0.90.00.7
Tibia length1.64.68.1-1.81.82.7-0.6-2.82.8-0.2-2.7
Ambulatory time before self-admin2.02.12.9-1.71.61.4-1.7-1.11.11.6-1.1
Ambulatory time after self-admin0.91.02.2-0.70.51.20.1-1.31.3-0.5-1.5
Bone: tissue strength2.92.84.7-2.12.21.7-1.6-1.51.51.4-1.3
Total heroin consumption2.63.18.02.1-1.9-0.82.80.3-0.2-2.80.1
Bone: trabecular number3.65.69.13.0-2.8-2.12.81.7-1.7-2.61.6
Bone: trabecular spacing0.40.51.0-1.00.80.3-0.9-0.00.11.0-0.1
Bone: trabecular thickness0.10.10.40.5-0.3-0.10.5-0.0-0.0-0.60.1
Bone: trabecular tissue density1.62.34.0-1.71.81.3-2.0-1.11.01.9-1.0
Water consumed over 24 hours1.21.52.5-1.11.21.5-0.3-1.61.6-0.1-1.5
Number of responses in last shaping day0.60.61.5-0.80.6-0.3-1.00.6-0.61.20.6