Hub : Genes

Rab3il1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL isoform ratio NM_134411.2 0.03 0.02 1.4e-03 0.02 0.01 0 0.01 6.0e-03 1.7e-02 1.2e-01 2.2e-02
2 IL gene expression Rab3il1 0.82 0.14 3.2e-03 0.01 0.03 0.04 0.01 1.8e-01 5.5e-02 4.6e-02 2.1e-01
3 NAcc mRNA stability Rab3il1 0.08 0.06 1.3e-06 0.05 0.04 0.04 0.04 2.3e-06 1.2e-05 2.5e-05 1.6e-05
4 LHb gene expression Rab3il1 0.24 0.14 2.5e-04 0.09 0.11 0.07 0.06 3.5e-03 1.3e-03 1.1e-02 1.8e-02
5 PL gene expression Rab3il1 0.27 0.13 0.0e+00 0.21 0.21 0.22 0.22 6.1e-23 1.6e-22 2.4e-23 2.1e-23
6 BLA gene expression Rab3il1 0.1 0.06 5.2e-07 0.11 0.11 0.09 0.11 1.1e-06 2.1e-06 1.7e-05 1.3e-06
7 NAcc gene expression Rab3il1 0.03 0.02 1.3e-04 0.04 0.03 0.03 0.03 3.4e-05 1.8e-04 9.6e-05 6.7e-05
8 PL intron excision ratio chr1_206673274_206674057 0.03 0.02 4.0e-03 0.01 0.01 0.01 0 5.4e-02 4.1e-02 6.3e-02 8.9e-02
9 Brain gene expression Rab3il1 0.13 0.07 4.9e-13 0.14 0.14 0.14 0.14 8.6e-13 6.6e-13 8.8e-13 3.1e-13
10 PL isoform ratio XM_039090191.1 0.03 0.03 8.3e-04 0.02 0.01 0 0.01 3.0e-03 7.7e-03 9.5e-02 7.0e-03
11 pVTA gene expression Rab3il1 0.13 0.08 6.0e-06 0.11 0.13 0.13 0.13 1.5e-05 3.5e-06 2.5e-06 3.0e-06
12 PL intron excision ratio chr1_206674203_206674702 0.02 0.02 7.7e-03 0.03 0.01 0.01 0.02 7.1e-04 1.0e-02 9.0e-03 2.9e-03
13 PL intron excision ratio chr1_206673274_206674702 0.05 0.03 1.1e-04 0.03 0.04 0.02 0.03 7.0e-04 7.1e-05 1.1e-03 3.4e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density0.10.20.50.7-0.6-0.50.40.1-0.4-0.40.70.10.1-0.5-0.0-0.7
Area under the delay curve0.20.20.50.2-0.1-0.20.30.2-0.4-0.40.50.50.4-0.70.3-0.5
BMI with tail3.09.614.72.6-3.5-2.62.92.6-2.8-2.83.52.8-3.0-3.8-3.1-3.8
BMI without tail1.53.04.01.5-1.8-1.51.71.8-1.8-1.81.71.8-1.7-2.0-1.7-1.9
Body weight3.815.821.93.8-3.5-3.84.14.0-4.2-4.24.34.3-3.1-4.7-3.0-4.4
Weight adjusted by age2.73.17.01.6-2.4-1.41.51.5-1.2-1.21.41.4-2.7-1.5-2.6-1.5
Bone surface1.11.93.51.8-1.4-1.71.40.9-1.3-1.31.91.2-0.5-1.5-0.6-1.8
Bone volume0.30.61.41.2-0.7-0.90.70.1-0.6-0.61.20.3-0.0-0.8-0.1-1.1
Breakpoint value in progressive ratio session2.12.33.21.7-1.8-1.71.61.7-1.3-1.31.21.4-1.7-1.2-1.8-1.1
Number of licking bursts0.00.00.2-0.20.40.1-0.1-0.0-0.0-0.00.00.20.0-0.00.1-0.0
Context. condit. distance diff. score0.10.10.2-0.3-0.20.4-0.3-0.30.40.4-0.3-0.2-0.00.1-0.10.2
Locomotion velocity, session 10.20.21.10.1-1.0-0.20.30.4-0.2-0.20.20.3-0.6-0.3-0.6-0.3
Locomotion distance, session 11.21.54.10.9-2.0-1.01.11.2-1.0-1.01.11.1-1.4-1.3-1.4-1.2
Locomotion velocity, session 23.33.94.31.8-1.9-2.02.01.9-2.0-2.02.02.1-2.0-2.1-1.9-2.0
Locomotion distance, session 20.71.01.80.5-1.2-0.60.91.2-1.0-1.00.71.1-1.3-0.9-1.3-0.8
Locomotion velocity, session 30.50.61.50.2-0.6-0.60.60.4-0.7-0.71.10.9-0.7-1.2-0.8-1.2
Locomotion distance, session 30.10.10.4-0.10.2-0.10.00.0-0.2-0.20.10.20.6-0.20.6-0.1
Stereotopy head waving bouts, day 30.10.20.6-0.2-0.40.10.20.2-0.4-0.40.50.4-0.3-0.7-0.3-0.7
Stereotopy head waving duration, day 30.10.10.3-0.2-0.00.20.20.2-0.4-0.40.30.4-0.3-0.5-0.4-0.5
Locomotion velocity, session 70.00.00.1-0.00.30.00.0-0.1-0.1-0.10.20.20.3-0.30.4-0.2
Locomotion distance, session 70.00.10.2-0.30.20.3-0.10.0-0.1-0.1-0.00.00.4-0.20.4-0.0
Stereotopy head waving bouts, day 70.20.30.40.5-0.5-0.60.50.3-0.4-0.40.60.5-0.6-0.5-0.6-0.7
Stereotopy head waving duration, day 71.92.32.91.7-1.4-1.71.61.4-1.5-1.51.71.6-1.2-1.6-1.2-1.6
Locomotion velocity, session 80.10.10.20.10.1-0.10.20.4-0.3-0.3-0.10.30.3-0.10.30.1
Locomotion distance, session 80.00.10.2-0.3-0.50.3-0.1-0.10.10.1-0.00.1-0.3-0.2-0.4-0.2
Degree of sensitization distance0.20.20.7-0.1-0.60.20.10.1-0.1-0.10.30.1-0.8-0.5-0.8-0.5
Degree of sensitization stereotypy1.01.11.61.3-1.1-1.31.10.8-0.8-0.81.20.9-1.1-0.9-1.1-1.1
Conditioned locomotion0.70.91.50.8-0.8-0.80.91.0-1.0-1.00.81.2-0.8-0.9-0.8-0.9
Cocaine response after cond. corrected0.20.30.8-0.9-0.10.8-0.5-0.30.40.4-0.6-0.4-0.20.5-0.40.4
Cocaine response after cond. not corrected0.30.30.6-0.7-0.30.7-0.6-0.60.70.7-0.6-0.7-0.20.6-0.40.4
Cocaine response before conditioning0.10.20.70.8-0.5-0.70.1-0.30.30.30.4-0.4-0.10.1-0.1-0.2
Saline control response2.22.94.01.9-2.0-1.71.81.9-1.8-1.81.61.8-1.4-1.6-1.5-1.5
Bone: connectivity density1.32.13.01.6-1.6-1.61.51.2-1.4-1.41.71.2-0.9-1.6-0.9-1.7
Bone: cortical apparent density0.40.50.90.9-0.6-0.90.80.8-0.7-0.70.60.6-0.7-0.6-0.6-0.5
Bone: cortical area0.50.71.51.2-1.0-1.20.90.5-0.8-0.81.10.5-0.4-0.7-0.3-1.0
Bone: cortical porosity0.00.00.1-0.00.3-0.00.00.2-0.1-0.1-0.20.2-0.00.3-0.10.3
Bone: cortical porosity0.10.10.40.40.0-0.30.40.6-0.4-0.40.00.6-0.3-0.0-0.40.0
Bone: cortical thickness2.43.95.82.3-1.9-2.42.22.3-2.2-2.21.82.0-1.4-1.6-1.4-1.6
Bone: cortical thickness0.20.30.50.7-0.4-0.70.60.7-0.7-0.70.40.6-0.2-0.2-0.2-0.3
Bone: cortical tissue density0.50.71.11.1-0.7-1.00.90.9-0.8-0.80.70.8-0.8-0.6-0.7-0.5
Condit. Reinf. active minus inactive responses1.31.43.71.1-1.9-1.11.01.0-0.9-0.91.00.9-1.6-0.9-1.6-1.1
Condit. Reinf. active-inactive response ratio0.70.82.20.6-1.5-0.70.70.9-0.5-0.50.40.6-1.4-0.3-1.4-0.4
Condit. Reinf. active responses1.21.54.11.0-2.0-1.11.00.8-0.8-0.81.10.7-1.7-1.0-1.7-1.2
Condit. Reinf. inactive responses0.10.10.3-0.1-0.50.1-0.2-0.40.30.30.2-0.4-0.3-0.2-0.3-0.3
Incentive salience index mean1.31.64.11.2-2.0-1.21.11.0-1.0-1.01.30.9-1.3-1.2-1.3-1.3
Condit. Reinf. lever presses0.50.61.20.8-1.1-0.90.70.4-0.7-0.71.10.6-0.2-1.0-0.3-1.1
Condit. Reinf. active minus inactive responses0.40.41.0-0.40.10.4-0.7-0.80.90.9-0.6-1.0-0.31.0-0.20.5
Condit. Reinf. active-inactive response ratio0.40.40.9-0.60.40.6-0.7-0.90.90.9-0.4-0.9-0.60.7-0.50.2
Condit. Reinf. active responses0.10.10.20.1-0.3-0.1-0.1-0.30.40.4-0.1-0.4-0.30.4-0.20.1
Condit. Reinf. inactive responses0.10.10.50.3-0.4-0.30.0-0.00.00.0-0.0-0.10.70.10.70.1
Condit. Reinf. lever presses0.60.81.41.1-1.0-1.10.80.4-0.6-0.61.10.5-1.2-0.7-1.1-1.0
Condit. Reinf. lever reinforcers received0.10.20.60.5-0.6-0.40.2-0.00.10.10.2-0.1-0.80.2-0.7-0.2
Conditioned reinforcement - actives2.12.13.3-1.41.01.3-1.5-1.71.71.7-1.5-1.80.91.80.91.4
Conditioned reinforcement - inactives0.70.81.5-1.00.60.9-1.0-1.21.21.2-0.6-0.90.40.80.40.5
Conditioned locomotion1.41.62.6-1.31.31.4-1.4-1.61.51.5-1.0-1.51.11.11.10.8
Patch foraging indifference point 0 sec0.50.91.30.9-1.0-1.11.01.1-0.9-0.91.00.8-0.6-1.1-0.6-0.9
Patch foraging indifference point AUC1.72.03.41.8-1.4-1.91.51.3-1.3-1.31.41.3-1.2-1.2-1.2-1.3
Delay disc. indifference point, 0s delay0.10.10.3-0.40.00.3-0.1-0.1-0.1-0.10.30.20.3-0.50.1-0.5
Delay disc. indifference point, 16s delay0.10.10.30.4-0.5-0.30.30.1-0.2-0.20.50.3-0.2-0.5-0.2-0.5
Delay disc. indifference point, 2s delay0.10.20.6-0.30.30.3-0.3-0.60.30.30.1-0.30.8-0.20.7-0.2
Delay disc. indifference point, 24s delay0.10.10.30.2-0.0-0.20.30.3-0.6-0.60.40.40.3-0.40.2-0.4
Delay disc. indifference point, 4s delay0.70.71.70.5-0.2-0.40.80.9-1.1-1.10.91.10.3-1.30.3-1.0
Delay disc. indifference point, 8s delay0.20.30.9-0.60.90.6-0.3-0.10.00.0-0.30.20.9-0.00.80.2
Indifference point function ln k2.73.86.7-2.61.92.5-2.2-2.01.91.9-1.9-1.81.61.51.51.6
Indifference point function log k2.73.86.7-2.61.92.5-2.2-2.01.91.9-1.9-1.81.61.51.51.6
Patch foraging total patch changes 0 sec0.50.81.30.9-0.9-1.01.01.1-1.0-1.00.90.8-0.5-1.0-0.5-0.8
Patch foraging total patch changes 12 sec6.48.210.93.1-2.7-3.33.13.2-3.0-3.02.72.8-2.5-2.7-2.5-2.5
Patch foraging total patch changes 18 sec0.50.61.31.0-0.8-1.10.90.9-0.8-0.80.70.6-0.5-0.6-0.4-0.6
Patch foraging total patch changes 24 sec7.49.110.83.1-2.6-3.33.23.1-3.1-3.13.13.1-2.5-3.3-2.5-3.0
Patch foraging total patch changes 6 sec1.01.52.31.2-1.1-1.51.31.3-1.3-1.31.31.2-0.6-1.4-0.6-1.3
Patch foraging time to switch 0 sec0.40.61.10.7-1.0-0.90.70.4-0.7-0.71.00.4-0.8-0.7-0.8-1.1
Patch foraging water rate 0 sec0.71.11.4-0.91.11.0-0.9-0.81.01.0-1.1-0.91.21.01.11.1
Patch foraging water rate 12 sec1.52.33.4-1.91.41.8-1.6-1.41.51.5-1.6-1.41.41.41.31.5
Patch foraging water rate 18 sec0.60.81.8-1.00.71.1-0.8-0.70.70.7-0.8-0.71.30.41.30.7
Patch foraging water rate 24 sec1.31.92.7-1.61.41.5-1.4-1.21.21.2-1.5-1.31.31.41.31.4
Patch foraging water rate 6 sec1.01.52.2-1.41.21.4-1.2-0.91.01.0-1.3-0.91.51.01.41.3
Seeking ratio, delayed vs. immediate footshock0.00.00.1-0.10.40.00.1-0.1-0.1-0.10.20.1-0.1-0.1-0.1-0.3
Distance traveled before self-admin1.81.93.31.8-1.7-1.61.41.0-1.1-1.11.41.1-1.5-1.1-1.3-1.3
Distance traveled after self-admin0.10.10.40.6-0.2-0.60.40.0-0.1-0.10.40.1-0.5-0.1-0.3-0.4
Extensor digitorum longus weight6.525.528.05.0-4.9-5.05.15.0-5.1-5.15.15.1-4.9-5.3-4.9-5.1
Bone: elastic displacement0.50.51.2-0.60.40.9-0.7-0.30.60.6-1.1-0.60.70.90.61.1
Bone: elastic work0.70.91.81.0-1.3-0.81.01.3-1.1-1.10.61.1-0.6-0.8-0.7-0.5
Bone: endosteal estimation1.02.24.8-1.61.11.6-1.7-2.21.71.7-0.8-1.71.50.91.40.7
Bone: endosteal perimeter1.83.67.7-1.91.72.0-2.1-2.82.22.2-1.1-2.31.71.41.71.0
Epididymis fat weight0.30.81.6-1.11.31.1-0.9-1.10.80.8-0.4-0.61.10.11.10.2
Delta time in closed arm before/after self-admin3.02.95.41.2-1.7-1.21.72.1-1.8-1.81.32.3-1.4-2.0-1.5-1.4
Delta time in open arm before/after self-admin1.31.32.21.3-1.3-1.51.10.9-0.9-0.91.10.8-1.5-0.8-1.5-1.0
Diff in mean of infusions in LGA sessions1.71.92.61.5-1.4-1.51.41.6-1.5-1.51.01.4-1.4-1.1-1.4-0.9
Delay discount exponential model param0.10.20.5-0.20.00.1-0.3-0.20.40.4-0.5-0.5-0.40.7-0.40.5
Extinction: sum of active levers before priming3.43.44.22.0-1.9-2.11.91.8-1.7-1.71.81.9-1.8-1.8-1.8-1.7
Active lever presses in extinction session 61.91.93.41.8-1.7-1.81.41.2-1.2-1.21.21.1-1.4-1.0-1.4-1.0
Bone: final force1.62.64.71.9-2.2-1.81.61.3-1.5-1.51.81.3-1.2-1.5-1.3-1.7
Bone: final moment1.52.44.61.8-2.1-1.71.61.3-1.5-1.51.71.2-1.1-1.5-1.2-1.7
Food consumed during 24 hour testing period0.30.40.6-0.50.20.3-0.6-0.60.70.7-0.6-0.50.70.70.70.6
Glucose2.63.95.8-2.41.82.4-2.1-2.12.02.0-1.8-1.91.91.51.91.5
Heart weight0.50.71.5-1.11.11.2-0.9-0.70.60.6-0.8-0.61.00.41.10.6
Delay discount hyperbolic model param0.20.20.6-0.20.00.2-0.3-0.20.40.4-0.6-0.5-0.40.7-0.40.6
Intermittent access intake day 1-15 change1.51.52.4-0.70.80.9-1.2-1.31.51.5-1.3-1.41.01.61.01.4
Intermittent access intake escalation0.90.91.5-0.40.40.8-0.9-1.01.21.2-1.0-1.10.61.20.61.0
Intermittent access intake escalation 20.10.10.20.3-0.4-0.1-0.1-0.30.40.4-0.2-0.50.00.50.00.4
Intermitt. access day 1 inactive lever presses1.01.12.0-1.21.31.1-1.1-1.41.41.4-0.6-1.00.60.60.60.5
Intermitt. access day 15 inactive lever presses0.20.21.00.4-0.1-0.30.2-0.30.10.10.90.0-0.4-0.7-0.4-1.0
Intermitt. access escalation Index0.20.10.5-0.20.50.4-0.3-0.40.20.2-0.1-0.10.7-0.10.70.0
Intermittent access day 1 total infusions0.30.30.9-0.70.80.7-0.6-1.00.60.60.2-0.40.2-0.20.2-0.4
Intermittent access day 15 total infusions2.52.84.7-1.51.51.7-1.8-2.22.02.0-1.3-1.91.41.51.41.1
Intermittent access terminal intake (last 3 days)0.30.41.1-0.30.10.5-0.7-1.10.90.9-0.2-0.80.20.40.20.1
Intermittent access total infusions0.50.51.5-0.60.70.8-0.8-1.21.01.0-0.2-0.90.40.40.40.1
Intermittent access day 1 locomotion0.20.21.0-0.10.10.10.1-0.2-0.1-0.10.80.2-0.2-0.9-0.2-1.0
Intermittent access day 15 total locomotion0.10.10.4-0.1-0.00.1-0.1-0.30.30.30.50.0-0.6-0.4-0.6-0.6
Intermittent access total locomotion0.20.31.30.1-0.10.0-0.0-0.70.20.20.9-0.1-0.5-0.7-0.5-1.1
Intermittent access standard deviation1.01.11.9-0.90.21.0-1.1-0.91.31.3-1.4-1.00.11.30.11.4
Left kidney weight0.10.20.70.20.6-0.10.30.1-0.4-0.40.70.50.5-0.80.4-0.7
Right kidney weight0.10.30.70.40.1-0.40.50.3-0.6-0.60.80.7-0.1-0.8-0.1-0.8
Cocaine induced anxiety0.20.30.70.2-0.8-0.60.50.5-0.3-0.30.50.4-0.8-0.3-0.8-0.5
Post-drug Anxiety0.60.71.30.6-1.1-0.90.80.7-0.6-0.60.80.6-1.1-0.5-1.1-0.8
Baseline Anxiety1.11.21.81.4-1.1-1.01.11.1-1.1-1.11.01.1-1.0-1.1-1.0-1.0
Tail length0.82.34.11.7-0.8-1.61.72.0-2.0-2.01.22.0-0.8-1.4-0.7-1.1
Length with tail2.07.210.22.8-1.7-2.82.92.8-3.1-3.12.93.2-1.6-3.0-1.6-2.7
Length without tail1.53.34.71.9-1.3-1.91.91.7-2.0-2.02.22.0-1.0-2.1-1.1-2.1
Times rat made contact with spout0.10.10.40.4-0.4-0.30.40.6-0.5-0.50.00.6-0.3-0.1-0.3-0.0
Lifetime Intake0.40.41.0-0.70.60.8-0.7-1.00.90.9-0.3-0.70.30.30.30.1
Liver weight, left0.60.92.1-0.91.00.9-0.9-0.70.80.8-0.9-0.71.40.71.50.9
Liver weight, right0.00.00.2-0.1-0.50.3-0.2-0.10.10.1-0.0-0.00.3-0.20.3-0.1
Locomotor activity0.61.02.1-1.21.01.2-0.8-0.40.60.6-1.1-0.71.30.81.41.1
Locomotor testing distance0.50.81.6-1.30.81.3-0.8-0.40.60.6-1.0-0.81.10.61.20.9
Locomotor testing rearing0.71.11.6-1.10.51.3-1.1-0.91.11.1-1.2-1.30.91.00.91.1
Locomotion in novel chamber2.02.54.0-1.51.31.4-1.7-2.01.91.9-1.2-1.71.41.41.41.1
Locomotion in novel chamber post-restriction1.72.13.0-1.61.41.5-1.5-1.21.41.4-1.7-1.41.11.51.11.7
Fecal boli incidents, locomotor time 10.30.40.9-0.30.10.3-0.6-0.70.90.9-0.5-0.9-0.30.7-0.20.5
Change in fecal boli incidents, locomotor task0.60.61.8-0.90.81.1-0.6-0.40.20.2-0.5-0.41.30.11.30.3
Time >=10cm from walls, locomotor time 12.02.03.4-1.41.31.4-1.6-1.81.81.8-1.1-1.70.61.40.71.0
Bouts of movement, locomotor time 10.30.31.10.7-0.5-0.60.50.8-0.3-0.3-0.10.3-1.00.2-1.00.3
Total resting periods, locomotor time 10.20.20.70.7-0.4-0.70.40.6-0.2-0.20.00.2-0.80.1-0.80.2
Rest time, locomotor task time 11.41.63.3-1.31.81.3-1.3-1.11.31.3-1.3-1.10.91.20.91.3
Distance moved, locomotor task time 10.30.41.00.6-1.0-0.60.50.3-0.4-0.40.70.6-0.5-0.7-0.6-0.7
Vertical activity count, locomotor time 10.60.61.0-0.80.50.9-0.8-0.70.80.8-0.8-0.61.00.60.80.7
Time >=10cm from walls, locomotor time 20.40.51.3-0.30.40.3-0.6-0.80.70.7-0.5-1.10.41.00.50.6
Bouts of movement, locomotor time 22.32.57.11.2-2.0-1.31.31.6-1.1-1.10.91.4-2.6-1.2-2.7-1.0
Total resting periods, locomotor time 21.71.86.30.8-1.7-0.90.91.3-0.7-0.70.61.1-2.4-0.9-2.5-0.7
Rest time, locomotor task time 22.42.74.3-2.11.82.1-1.8-1.51.81.8-1.9-1.40.71.60.71.7
Distance moved, locomotor task time 20.20.30.90.8-0.5-0.90.60.4-0.5-0.50.50.40.1-0.3-0.0-0.3
Vertical activity count, locomotor time 20.20.20.9-0.20.50.2-0.20.2-0.1-0.1-0.6-0.00.90.30.70.7
Light reinforcement 10.20.41.5-0.20.30.3-0.5-0.70.60.6-0.5-1.20.70.90.60.5
Light reinforcement 20.40.61.4-0.30.70.4-0.7-1.20.90.9-0.2-1.00.90.61.10.3
Bone: marrow area1.22.55.2-1.71.31.8-1.8-2.31.81.8-1.0-1.81.61.01.60.8
Bone: maximum diameter0.10.10.50.5-0.3-0.50.3-0.2-0.2-0.20.7-0.0-0.1-0.3-0.0-0.6
Bone: maximum force2.13.65.72.2-2.4-2.01.91.3-1.7-1.72.41.5-1.3-2.1-1.4-2.3
Bone: maximum moment1.93.35.32.1-2.3-1.91.81.3-1.6-1.62.31.4-1.2-2.0-1.3-2.2
Mean time between licks in bursts0.91.22.30.6-1.3-0.71.01.4-1.2-1.20.61.5-1.3-1.1-1.3-0.8
Mean num. licks in bursts0.00.00.2-0.0-0.30.1-0.10.20.10.1-0.4-0.1-0.00.4-0.00.4
Cd content in liver1.11.21.7-1.00.50.9-1.1-1.11.21.2-1.1-1.31.11.11.01.0
Co content in liver2.12.53.9-1.51.61.5-1.5-1.21.51.5-1.9-1.51.31.91.32.0
Cu content in liver0.20.30.60.40.1-0.40.60.7-0.8-0.80.40.8-0.2-0.5-0.2-0.4
Fe content in liver0.00.00.10.0-0.0-0.10.10.0-0.1-0.10.10.3-0.30.0-0.4-0.1
K content in liver0.90.91.71.0-0.9-1.00.90.6-0.8-0.81.31.0-0.6-1.2-0.6-1.3
Mg content in liver0.50.51.20.5-1.1-0.50.50.3-0.5-0.50.90.6-0.4-1.0-0.4-1.0
Mn content in liver1.61.82.31.4-1.0-1.51.41.2-1.4-1.41.51.5-1.0-1.4-1.0-1.4
Na content in liver0.50.51.10.9-1.0-0.80.70.5-0.5-0.50.80.6-0.5-0.7-0.5-0.8
Rb content in liver1.31.62.2-1.51.11.5-1.4-1.41.31.3-1.2-1.21.21.01.21.0
Se content in liver0.30.40.70.6-0.1-0.60.60.3-0.4-0.40.70.7-0.8-0.6-0.8-0.7
Sr content in liver6.96.47.42.6-2.5-2.62.62.7-2.5-2.52.32.6-2.7-2.3-2.7-2.2
Zn content in liver4.95.48.22.4-2.9-2.42.32.2-2.1-2.12.22.3-2.4-2.1-2.4-2.2
Bone: minimum diameter0.61.13.0-1.00.81.0-1.1-1.71.31.3-0.4-1.31.10.61.10.2
Time in familiar zone, hab. session 10.10.10.30.4-0.6-0.20.1-0.10.10.10.2-0.1-0.2-0.2-0.3-0.2
Time in novel zone, hab. session 11.41.42.0-1.41.21.3-1.2-1.01.11.1-1.3-1.01.11.21.01.3
Total zone transitions, hab. session 10.30.50.80.5-0.8-0.70.80.9-0.8-0.80.50.8-0.5-0.5-0.6-0.5
Total locomotion distance, hab. session 10.10.10.4-0.2-0.60.1-0.0-0.10.00.00.20.0-0.5-0.2-0.5-0.3
Locomotion velocity, hab. session 10.40.51.10.4-1.1-0.50.60.6-0.6-0.60.60.6-1.0-0.7-1.0-0.7
Time in familiar zone, hab. session 20.90.91.2-0.80.90.8-0.9-0.81.01.0-1.0-1.10.91.10.91.1
Time in novel zone, hab. session 21.01.01.50.8-1.2-0.81.00.9-1.0-1.01.01.1-0.9-1.2-0.9-1.1
Total zone transitions, hab. session 21.41.83.91.1-2.0-1.31.31.4-1.3-1.31.31.2-1.0-1.4-1.0-1.3
Total locomotion distance, hab. session 20.30.31.40.1-1.2-0.40.40.5-0.4-0.40.50.4-0.8-0.6-0.8-0.6
Locomotion velocity, hab. session 20.20.21.0-0.1-1.0-0.20.20.2-0.3-0.30.40.2-0.6-0.5-0.6-0.5
Novel to familiar place preference ratio2.32.33.41.4-1.1-1.51.61.6-1.8-1.81.61.8-1.0-1.7-1.0-1.5
Novelty place preference1.41.42.21.0-0.7-1.11.21.2-1.4-1.41.21.5-0.8-1.4-0.7-1.2
Time in novel zone, NPP test1.61.72.41.1-0.9-1.21.31.4-1.5-1.51.31.5-1.1-1.4-1.0-1.3
Total zone transitions, NPP test1.42.13.51.3-1.9-1.41.51.7-1.5-1.51.21.4-1.2-1.3-1.3-1.2
Total locomotion distance, NPP test0.20.30.60.2-0.8-0.40.50.7-0.6-0.60.40.6-0.4-0.6-0.4-0.5
Locomotion velocity, NPP test0.10.10.30.1-0.4-0.30.40.5-0.5-0.50.30.50.0-0.40.0-0.3
Intraocular pressure0.10.20.5-0.50.50.4-0.4-0.20.40.4-0.7-0.3-0.20.7-0.10.7
Delta distance traveled before/after self-admin0.70.81.3-1.11.20.9-0.9-0.70.80.8-0.9-0.70.80.80.80.9
Delta ambulatory time before/after self-admin1.01.01.4-1.21.21.2-1.0-0.80.90.9-1.2-0.90.91.01.01.1
Parametrial fat weight1.52.95.2-1.92.31.7-1.8-2.21.71.7-1.1-1.81.61.11.71.0
Pavlov. Cond. lever latency0.91.22.6-1.21.61.2-1.1-0.81.01.0-1.3-0.90.51.20.51.3
Pavlov. Cond. magazine entry latency0.81.11.91.2-1.4-1.20.90.5-0.7-0.71.30.7-1.0-1.0-1.0-1.3
Pavlov. Cond. change in total contacts0.20.20.80.7-0.9-0.70.40.1-0.1-0.10.60.2-0.4-0.3-0.5-0.6
Pavlov. Cond. index score0.40.41.00.9-1.0-0.90.60.4-0.4-0.40.80.4-0.5-0.6-0.5-0.8
Pavlov. Cond. latency score0.30.41.00.8-1.0-0.80.50.3-0.4-0.40.80.4-0.2-0.6-0.2-0.7
Pavlov. Cond. lever contacts0.10.20.50.5-0.7-0.50.30.1-0.2-0.20.60.20.1-0.50.1-0.5
Pavlov. Cond. magazine entry number0.40.51.1-1.00.91.1-0.7-0.40.50.5-0.8-0.50.80.40.80.7
Pavlov. Cond. intertrial magazine entries0.00.00.10.2-0.2-0.20.20.3-0.2-0.2-0.0-0.00.10.20.10.2
Pavlov. Cond. lever-magazine prob. diff.0.50.61.31.0-1.2-1.00.80.5-0.6-0.60.90.6-0.7-0.7-0.7-0.9
Pavlov. Cond. response bias0.50.61.11.0-1.0-1.00.70.4-0.5-0.50.90.5-0.8-0.6-0.8-0.8
Pavlov. Cond. lever latency0.50.71.9-0.81.00.7-0.6-0.20.30.3-0.9-0.31.40.71.31.0
Pavlov. Cond. magazine entry latency4.95.69.72.6-2.7-2.62.21.9-1.8-1.82.32.0-3.1-1.9-3.1-2.2
Pavlov. Cond. change in total contacts1.21.64.01.5-1.8-1.51.00.4-0.4-0.41.30.5-2.0-0.7-1.9-1.2
Pavlov. Cond. index score2.73.47.32.1-2.2-2.11.61.0-1.1-1.11.91.2-2.7-1.4-2.6-1.9
Pavlov. Cond. latency score2.53.16.52.0-2.1-1.91.51.0-1.1-1.11.91.2-2.5-1.4-2.5-1.9
Pavlov. Cond. lever contacts0.50.72.80.7-1.1-0.80.50.2-0.2-0.20.60.2-1.7-0.3-1.6-0.6
Pavlov. Cond. magazine entry number7.59.214.6-3.33.43.3-2.9-2.42.52.5-3.0-2.63.82.53.82.9
Pavlov. Cond. intertrial magazine entries1.82.43.3-1.51.81.5-1.5-1.31.31.3-1.5-1.71.81.51.81.5
Pavlov. Cond. lever-magazine prob. diff.3.03.88.02.2-2.3-2.21.71.1-1.2-1.22.01.3-2.8-1.5-2.8-2.0
Pavlov. Cond. response bias1.72.35.61.6-1.8-1.61.30.9-0.9-0.91.41.0-2.4-1.0-2.3-1.4
Time in closed arm before self-admin0.10.10.40.10.2-0.1-0.2-0.60.50.50.1-0.60.20.30.30.0
Time in closed arm after self-admin0.20.20.4-0.50.40.6-0.5-0.40.50.5-0.5-0.30.50.20.50.4
Time in open arm before self-admin0.80.91.7-1.31.11.3-0.8-0.30.30.3-1.1-0.41.20.81.21.0
Time in open arm after self-admin0.10.10.2-0.10.2-0.00.00.3-0.3-0.3-0.40.1-0.10.4-0.00.4
Bone: periosteal estimation0.10.21.0-0.20.10.2-0.4-1.00.50.50.3-0.70.50.00.5-0.3
Bone: periosteal perimeter0.10.10.5-0.1-0.10.0-0.3-0.70.40.40.2-0.60.20.20.3-0.2
Bone: post-yield work0.40.51.9-0.40.20.4-0.6-1.40.90.90.3-0.90.9-0.10.8-0.4
Progressive ratio test 1 active lever presses1.31.42.0-1.01.41.2-1.2-1.31.41.4-1.0-1.11.11.01.11.0
Progressive ratio test 1 breakpoint1.51.62.2-1.01.41.3-1.3-1.41.51.5-1.2-1.21.11.21.11.1
Progressive ratio test 1 inactive lever presses0.40.51.10.3-0.3-0.50.60.5-0.5-0.50.80.8-0.8-1.0-0.8-0.9
Progressive ratio test 2 active lever presses1.11.22.1-0.91.21.1-1.2-1.51.31.3-0.7-1.20.90.90.90.7
Progressive ratio test 2 breakpoint2.02.33.4-1.31.71.4-1.6-1.91.71.7-1.2-1.61.51.41.31.1
Progressive ratio test 2 inactive lever presses0.20.30.9-0.60.50.4-0.5-0.90.70.70.0-0.60.10.20.1-0.2
Incentive Sensitization - Responses0.10.10.20.4-0.3-0.30.2-0.1-0.2-0.20.50.0-0.1-0.3-0.1-0.5
Incentive Sensitization - Breakpoint0.10.10.30.3-0.1-0.30.1-0.3-0.1-0.10.5-0.00.0-0.3-0.0-0.5
Sum of active levers in priming session hrs 5-60.60.61.61.2-0.8-1.20.80.6-0.5-0.50.60.5-0.9-0.2-0.9-0.4
Progressive ratio0.00.00.10.10.0-0.0-0.1-0.30.30.30.10.1-0.2-0.2-0.2-0.2
Food seeking constrained by brief footshock0.10.10.2-0.30.10.3-0.2-0.10.20.2-0.4-0.50.40.30.40.3
Seeking ratio, punishment vs. effort0.10.10.1-0.4-0.00.20.00.3-0.4-0.4-0.2-0.20.30.10.30.2
Retroperitoneal fat weight2.37.613.3-3.23.63.1-2.8-2.92.52.5-2.1-2.23.31.73.31.9
Reaction time number correct0.30.40.70.8-0.8-0.60.70.8-0.6-0.60.50.7-0.2-0.6-0.0-0.4
Reaction time mean minus median0.30.41.20.7-0.6-0.80.50.6-0.3-0.30.40.5-1.1-0.2-1.0-0.3
Reaction time mean minus median AUC0.10.20.70.3-0.4-0.40.30.5-0.1-0.1-0.10.1-0.90.2-0.70.2
Reaction time num false alarms0.20.30.8-0.50.80.5-0.30.1-0.0-0.0-0.70.10.90.40.80.7
Reaction time num false alarms AUC0.20.20.60.00.4-0.00.30.7-0.7-0.7-0.20.70.5-0.10.60.3
Reaction time trials correct on left0.30.40.70.8-0.8-0.60.70.8-0.6-0.60.50.7-0.2-0.6-0.0-0.4
Reaction time trials on left0.30.40.70.9-0.8-0.70.70.8-0.6-0.60.50.7-0.2-0.6-0.1-0.4
Reaction time mean0.10.20.90.2-0.3-0.1-0.2-0.20.50.5-0.2-0.2-0.90.4-0.80.2
Reaction time mean AUC0.20.30.7-0.1-0.10.1-0.4-0.50.80.8-0.4-0.5-0.70.6-0.60.4
Median of all reaction times0.10.21.00.4-0.5-0.30.1-0.00.30.30.1-0.0-1.00.0-0.7-0.1
Reaction time omissions0.10.10.20.20.3-0.40.30.5-0.3-0.3-0.10.4-0.10.1-0.00.2
Reaction time false alarm rate0.10.20.7-0.50.80.4-0.20.0-0.1-0.1-0.50.10.70.30.60.5
Reaction time premature initiation rate3.64.87.22.3-1.6-2.22.32.0-2.3-2.32.52.3-1.5-2.7-1.4-2.5
Reaction time premature initiations4.36.08.02.7-2.0-2.62.62.5-2.7-2.72.62.7-1.6-2.8-1.5-2.5
Std. dev. reaction times0.10.20.4-0.10.20.1-0.3-0.10.50.5-0.6-0.2-0.50.7-0.30.7
Reaction time trials completed0.30.40.70.9-0.8-0.70.70.8-0.6-0.60.50.7-0.2-0.6-0.1-0.4
Reaction time trials AUC0.20.30.60.7-0.8-0.50.60.8-0.6-0.60.40.6-0.1-0.60.0-0.4
Run reversals in cocaine runway, females0.90.92.00.7-0.6-0.70.90.9-1.2-1.21.11.1-0.5-1.4-0.4-1.2
Run reversals in cocaine runway, males1.11.12.9-1.01.30.8-0.8-0.70.60.6-0.8-0.71.70.81.71.0
Latency to leave start box in cocaine runway0.40.41.0-0.50.80.5-0.6-0.90.50.5-0.0-0.61.00.11.0-0.0
Latency to leave start box in cocaine runway, F0.10.10.20.20.2-0.20.1-0.1-0.1-0.10.50.10.2-0.40.1-0.5
Latency to leave start box in cocaine runway, M3.63.44.6-1.81.81.9-1.9-2.01.81.8-1.6-1.92.21.62.21.6
Std. dev. time between licks in bursts0.10.20.4-0.60.40.5-0.4-0.10.30.3-0.40.10.60.10.60.4
Total sessions with >9 infusions0.80.91.5-1.21.11.2-1.0-1.11.21.2-0.7-0.90.50.60.50.4
Short access day 1 total inactive lever presses0.50.60.9-0.90.91.0-0.8-0.90.80.8-0.5-0.50.70.40.70.4
Short access day 10 total inactive lever presses1.61.83.0-1.71.41.7-1.5-1.21.31.3-1.4-1.01.21.21.21.3
Short access day 1 total infusions0.40.51.3-1.10.70.9-0.8-0.70.80.8-0.6-0.50.30.40.30.4
Short access day 10 total infusions0.10.20.5-0.30.30.4-0.2-0.60.40.40.5-0.1-0.2-0.5-0.2-0.7
Short access total infusions0.10.10.3-0.50.20.5-0.3-0.40.40.40.0-0.1-0.0-0.2-0.1-0.3
Short access day 1 locomotion0.40.41.00.3-0.7-0.30.50.5-0.4-0.40.70.7-0.7-1.0-0.7-0.8
Short access day 10 total locomotion0.20.31.0-0.1-0.3-0.00.2-0.1-0.2-0.20.80.3-0.7-0.7-0.7-1.0
Short access total locomotion0.80.92.00.6-0.8-0.50.70.5-0.6-0.61.20.8-1.1-1.4-1.1-1.4
One hour access (0.3 mA shock)3.03.55.2-1.91.91.9-2.0-2.32.12.1-1.5-2.11.51.81.51.4
Compulsive drug intake0.90.92.20.7-0.9-0.71.01.5-1.4-1.40.31.1-0.7-0.6-0.7-0.3
One hour access (shock baseline)4.45.17.5-2.22.22.1-2.4-2.72.72.7-1.8-2.51.92.21.91.8
Social response proportion0.10.20.70.4-0.2-0.40.20.0-0.2-0.20.30.20.8-0.20.9-0.2
Social responses0.10.10.70.20.2-0.30.10.2-0.1-0.1-0.10.10.90.20.80.3
Social time0.00.10.20.1-0.1-0.10.10.4-0.1-0.1-0.40.10.00.30.20.5
Soleus weight2.67.89.5-2.92.32.8-2.9-2.92.92.9-2.7-3.12.62.82.72.7
Bone: stiffness0.40.61.21.0-1.0-1.10.80.3-0.6-0.61.10.3-0.3-0.8-0.4-1.0
Tibialis anterior weight10.234.939.16.0-5.6-6.06.16.3-6.2-6.25.76.0-5.5-5.8-5.6-5.6
Time to tail flick, vehicle, before self-admin0.70.71.40.5-0.7-0.80.70.5-0.8-0.81.10.8-0.8-1.0-0.8-1.2
Time to tail flick, vehicle, after self-admin0.80.81.40.9-0.8-0.70.90.8-0.8-0.80.91.1-0.9-1.2-0.8-1.0
Time to tail flick, test, before self-admin0.30.30.80.2-0.1-0.20.40.5-0.9-0.90.70.6-0.1-0.9-0.1-0.8
Time to tail flick, test, after self-admin0.20.20.4-0.30.50.4-0.4-0.30.30.3-0.5-0.40.60.60.60.5
Delta time to tail flick, vehicle, before/after SA0.00.00.10.4-0.2-0.00.20.3-0.1-0.10.00.20.0-0.20.0-0.0
Delta time to tail flick, test, before/after SA0.20.10.50.1-0.1-0.0-0.2-0.10.40.4-0.6-0.3-0.10.7-0.10.7
Tibia length1.33.65.42.3-1.9-2.32.01.6-1.8-1.82.31.7-1.3-2.0-1.5-2.1
Ambulatory time before self-admin1.41.42.81.7-1.6-1.61.20.8-0.9-0.91.30.8-1.2-0.8-1.2-1.1
Ambulatory time after self-admin0.10.20.40.6-0.3-0.60.3-0.30.20.20.6-0.2-0.4-0.1-0.2-0.6
Bone: tissue strength0.60.60.9-0.70.50.8-0.8-0.80.80.8-0.7-0.90.90.80.70.7
Total heroin consumption3.44.05.52.2-2.2-2.22.12.4-2.1-2.11.52.1-2.0-1.6-2.0-1.4
Bone: trabecular number0.50.81.31.1-1.0-0.90.80.5-0.8-0.81.20.5-0.6-1.0-0.6-1.2
Bone: trabecular spacing0.30.30.8-0.60.00.5-0.5-0.20.60.6-0.9-0.6-0.00.90.10.9
Bone: trabecular thickness0.60.71.1-0.50.90.7-0.8-1.00.80.8-0.5-1.01.10.70.90.5
Bone: trabecular tissue density3.85.46.1-2.52.42.3-2.4-2.22.32.3-2.4-2.32.12.32.12.4
Water consumed over 24 hours0.20.20.50.6-0.0-0.60.50.4-0.6-0.60.40.7-0.1-0.3-0.1-0.3
Number of responses in last shaping day0.10.10.50.2-0.4-0.20.30.5-0.2-0.20.10.7-0.3-0.5-0.2-0.2