Atp11b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL alternative TSS XM_039103613.1 0.04 0.03 4.6e-04 0.02 0.02 0.01 0.01 5.9e-03 3.9e-03 1.0e-02 1.6e-02
2 NAcc alternative TSS XM_039103613.1 0.05 0.06 9.2e-03 0.01 0.01 0.01 0.01 1.6e-02 5.4e-02 2.7e-02 6.0e-02
3 PL isoform ratio XM_039103612.1 0.05 0.04 1.3e-04 0.02 0.02 0.01 0.02 9.3e-04 2.0e-03 7.1e-03 4.2e-03
4 PL isoform ratio XM_039103616.1 0.05 0.04 3.6e-05 0.03 0.03 0.02 0.03 1.7e-04 3.5e-04 9.8e-04 6.3e-04
5 Liver alternative polyA XM_039103613.1 0.03 0.03 2.7e-03 0 0 0 0 1.5e-01 2.3e-01 2.2e-01 2.2e-01
6 PL alternative TSS XM_039103616.1 0.04 0.03 9.1e-04 0.02 0.02 0.01 0.01 6.6e-03 6.6e-03 1.6e-02 1.9e-02
7 NAcc isoform ratio XM_039103616.1 0.04 0.04 4.6e-03 0.01 0.01 0.01 0.01 4.1e-02 2.4e-02 2.4e-02 6.6e-02
8 Liver alternative polyA XM_039103613.1 0.04 0.03 1.4e-03 0 0 0 0 1.4e-01 2.1e-01 1.4e-01 2.4e-01
9 Adipose mRNA stability Atp11b 0.14 0.08 1.9e-13 0.07 0.07 0.07 0.07 1.7e-08 2.4e-08 1.1e-08 1.5e-08
10 Liver alternative polyA XM_039103615.1 0.04 0.03 8.6e-04 0 0 0 0 1.2e-01 1.3e-01 7.9e-02 1.9e-01
11 Liver alternative polyA XM_039103615.1 0.04 0.03 1.2e-03 0 0 0 0 1.3e-01 1.2e-01 9.3e-02 1.8e-01
12 Adipose gene expression Atp11b 0.1 0.06 9.6e-09 0.05 0.05 0.05 0.05 2.6e-06 1.4e-06 1.3e-06 2.6e-06
13 Eye gene expression Atp11b 0.84 0.17 3.6e-03 0 0.05 0.01 0.04 2.8e-01 6.3e-02 2.5e-01 9.3e-02
14 Liver mRNA stability Atp11b 0.05 0.03 2.7e-04 0 0.01 0 0 1.2e-01 1.5e-02 1.8e-01 9.0e-02
15 NAcc alternative TSS XM_039103616.1 0.07 0.07 4.6e-03 0.01 0.01 0.01 0.01 3.1e-02 2.4e-02 1.4e-02 2.3e-02
16 RMTg gene expression Atp11b 0.63 0.15 6.3e-13 0.36 0.35 0.37 0.4 2.0e-10 2.7e-10 7.0e-11 8.0e-12
17 Liver gene expression Atp11b 0.22 0.14 1.9e-13 0.08 0.08 0.07 0.08 3.4e-09 4.3e-09 1.6e-08 5.2e-09
18 pVTA intron excision ratio chr2_118672845_118684194 0.24 0.13 8.4e-08 0.21 0.16 0.19 0.2 1.3e-09 2.4e-07 1.1e-08 7.5e-09
19 pVTA gene expression Atp11b 0.35 0.15 1.1e-10 0.2 0.2 0.23 0.19 5.9e-09 3.0e-09 1.7e-10 8.1e-09
20 Brain intron excision ratio chr2_118672845_118684194 0.12 0.07 9.6e-10 0.12 0.11 0.11 0.12 2.1e-11 2.0e-10 1.3e-10 5.2e-11
21 Brain isoform ratio XM_039103612.1 0.04 0.03 3.7e-03 0.02 0.02 0.02 0.01 5.1e-03 7.4e-03 3.5e-03 1.7e-02
22 Brain gene expression Atp11b 0.24 0.11 0.0e+00 0.25 0.26 0.25 0.25 2.7e-23 1.4e-23 7.3e-23 4.9e-23
23 LHb gene expression Atp11b 0.47 0.17 2.7e-08 0.29 0.34 0.31 0.32 1.0e-07 7.8e-09 3.4e-08 1.9e-08
24 pVTA intron excision ratio chr2_118674789_118677097 0.09 0.06 4.6e-03 0.01 0.06 0.05 0.04 7.6e-02 1.5e-03 3.2e-03 6.3e-03
25 NAcc gene expression Atp11b 0.11 0.11 1.3e-05 0.04 0.04 0.02 0.04 3.9e-05 2.5e-05 2.1e-03 5.4e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25
Bone: apparent density0.20.41.1-0.60.20.2-0.2-0.2-0.2-0.20.3-0.9-0.1-0.4-0.90.9-0.30.00.30.8-0.6-0.7-1.0-0.50.91.1-1.10.9
Area under the delay curve1.11.12.9-1.41.01.0-1.0-1.0-1.0-0.9-0.4-1.60.70.7-1.41.7-0.00.20.91.2-1.2-1.1-1.20.01.11.3-1.41.2
BMI with tail5.016.328.6-5.25.15.4-5.4-5.1-5.3-5.1-4.6-4.84.54.4-4.74.64.2-4.6-2.63.82.02.02.13.6-1.6-0.80.5-0.5
BMI without tail1.42.86.5-2.52.32.4-2.4-2.2-2.4-2.2-1.5-2.01.41.2-1.82.51.3-2.5-0.51.10.30.10.00.90.10.5-0.60.9
Body weight4.016.728.5-5.05.05.3-5.3-5.0-5.2-5.1-4.7-4.84.84.7-4.74.44.3-4.3-2.84.22.22.32.33.9-1.8-1.20.9-0.9
Weight adjusted by age0.20.31.40.5-0.4-0.40.40.30.50.50.40.8-0.5-0.41.0-0.4-0.5-0.00.5-1.2-0.3-0.3-0.2-0.70.20.1-0.10.4
Bone surface0.50.82.1-0.80.80.8-0.8-0.9-0.8-0.9-0.9-1.11.01.0-1.20.51.0-0.9-1.21.51.00.90.70.9-0.7-0.60.6-0.7
Bone volume0.10.10.7-0.40.20.3-0.3-0.3-0.3-0.3-0.1-0.70.20.1-0.70.40.1-0.3-0.40.80.20.0-0.30.10.20.2-0.20.1
Breakpoint value in progressive ratio session2.22.48.2-1.51.61.4-1.4-1.5-1.5-1.5-1.6-2.21.81.6-2.31.01.7-1.0-1.42.91.11.41.41.5-1.1-0.90.8-1.3
Number of licking bursts2.42.95.2-2.12.12.1-2.1-2.1-2.1-2.1-1.9-2.22.01.9-2.31.91.7-1.8-1.22.00.80.90.91.2-0.7-0.40.3-0.4
Context. condit. distance diff. score1.51.85.6-0.3-0.2-0.20.20.20.20.31.1-0.4-1.0-1.1-0.21.0-1.30.81.9-0.4-2.1-2.1-2.4-1.42.12.2-2.22.0
Locomotion velocity, session 12.02.15.2-0.20.60.6-0.6-0.6-0.6-0.7-1.3-0.41.21.2-0.6-0.61.6-1.4-2.31.32.32.31.91.6-2.1-2.12.1-2.0
Locomotion distance, session 13.03.97.5-1.01.51.5-1.5-1.5-1.5-1.6-2.2-1.22.12.1-1.50.22.4-2.0-2.72.02.62.62.22.1-2.4-2.32.2-2.3
Locomotion velocity, session 22.42.86.3-0.41.01.1-1.1-1.1-1.1-1.2-1.7-0.11.31.2-0.2-0.32.0-2.4-2.30.52.42.52.22.2-2.4-2.42.3-2.0
Locomotion distance, session 21.62.35.0-0.51.00.9-0.9-0.9-0.9-1.1-1.6-0.41.41.4-0.6-0.21.8-1.5-2.20.92.22.22.01.8-2.1-2.02.0-2.0
Locomotion velocity, session 30.10.10.20.1-0.1-0.00.00.00.00.0-0.00.10.0-0.00.1-0.30.2-0.3-0.40.10.50.40.20.3-0.3-0.40.4-0.3
Locomotion distance, session 30.00.10.2-0.00.10.1-0.1-0.1-0.1-0.1-0.20.00.20.2-0.1-0.10.30.1-0.30.10.30.40.30.3-0.3-0.30.3-0.4
Stereotopy head waving bouts, day 30.70.82.30.7-0.3-0.30.30.30.30.2-0.20.70.0-0.00.7-1.10.6-0.6-1.2-0.21.41.41.00.9-1.4-1.51.5-1.4
Stereotopy head waving duration, day 30.10.10.50.10.00.1-0.1-0.1-0.1-0.1-0.10.1-0.0-0.10.2-0.20.3-0.7-0.4-0.00.50.50.40.5-0.5-0.50.5-0.3
Locomotion velocity, session 70.80.92.0-0.20.50.5-0.5-0.5-0.5-0.6-0.9-0.20.80.8-0.4-0.31.1-0.9-1.40.71.41.41.41.2-1.3-1.31.3-1.3
Locomotion distance, session 70.40.51.00.9-1.0-1.01.01.01.00.90.90.7-0.8-0.80.6-0.8-0.80.90.3-0.4-0.3-0.3-0.3-0.70.40.2-0.20.1
Stereotopy head waving bouts, day 70.91.01.6-0.91.11.1-1.1-1.1-1.1-1.1-1.1-0.81.00.9-0.90.61.3-1.3-1.00.80.91.01.01.2-0.9-0.80.8-0.9
Stereotopy head waving duration, day 70.50.71.6-0.70.90.9-0.9-0.9-0.9-0.9-0.9-0.50.70.6-0.60.41.0-1.3-0.90.50.80.90.81.0-0.9-0.80.7-0.7
Locomotion velocity, session 80.70.92.4-1.41.21.2-1.2-1.2-1.2-1.3-0.7-1.20.70.7-1.11.60.5-0.90.10.5-0.4-0.4-0.70.60.40.6-0.70.6
Locomotion distance, session 80.40.61.7-1.21.11.1-1.1-1.1-1.1-1.1-0.7-1.10.70.6-1.01.30.6-0.9-0.20.6-0.1-0.1-0.30.50.20.4-0.50.4
Degree of sensitization distance0.90.91.41.0-1.1-1.11.11.11.11.11.20.9-1.1-1.11.0-0.7-1.10.90.9-0.9-0.8-0.8-0.9-0.90.80.6-0.60.7
Degree of sensitization stereotypy0.60.61.0-1.01.01.0-1.0-1.0-1.0-1.0-0.9-0.90.90.8-1.00.80.9-0.8-0.50.80.40.50.60.7-0.4-0.20.2-0.4
Conditioned locomotion2.83.24.91.8-2.0-2.02.02.22.02.12.21.7-2.1-2.11.8-1.4-2.12.21.8-1.6-1.6-1.6-1.6-1.51.41.1-1.00.9
Cocaine response after cond. corrected1.51.73.70.4-0.8-0.80.80.90.80.81.30.6-1.3-1.20.70.2-1.51.11.7-1.3-1.7-1.8-1.9-1.61.71.7-1.71.8
Cocaine response after cond. not corrected0.80.81.40.8-0.9-0.90.91.00.90.91.11.0-1.1-1.01.0-0.6-1.11.00.8-1.2-0.7-0.9-0.9-1.10.80.6-0.60.7
Cocaine response before conditioning1.51.85.20.40.20.2-0.2-0.1-0.2-0.2-0.90.30.80.80.1-1.11.3-0.8-1.90.62.02.12.31.3-2.1-2.22.2-2.2
Saline control response0.91.23.10.10.40.4-0.4-0.4-0.4-0.4-1.00.20.80.9-0.0-0.71.2-0.8-1.40.31.41.71.41.3-1.7-1.81.8-1.8
Bone: connectivity density1.11.74.0-1.51.41.5-1.5-1.4-1.5-1.5-1.3-1.71.41.2-1.81.21.4-1.5-1.32.00.90.90.91.0-0.7-0.40.4-0.6
Bone: cortical apparent density0.50.61.21.0-1.0-1.01.01.01.01.00.91.0-1.0-1.10.9-1.0-0.70.70.5-0.7-0.4-0.30.2-0.80.10.00.0-0.1
Bone: cortical area0.71.01.5-1.11.21.1-1.1-1.2-1.1-1.2-1.1-1.21.21.2-1.10.91.0-1.2-1.01.20.80.70.81.1-0.5-0.30.3-0.3
Bone: cortical porosity0.30.31.4-0.40.20.3-0.3-0.3-0.3-0.20.00.2-0.2-0.00.50.7-0.3-0.30.7-1.1-0.6-0.6-0.9-0.20.70.7-0.81.2
Bone: cortical porosity0.20.31.60.0-0.2-0.10.10.10.10.20.30.6-0.4-0.30.80.2-0.4-0.10.7-1.3-0.5-0.5-0.7-0.30.60.5-0.60.9
Bone: cortical thickness0.10.20.50.1-0.3-0.30.30.30.30.20.50.1-0.4-0.30.30.1-0.60.40.5-0.4-0.5-0.6-0.4-0.30.70.7-0.60.7
Bone: cortical thickness0.20.30.5-0.40.50.5-0.5-0.5-0.5-0.5-0.6-0.30.50.6-0.30.20.5-0.7-0.70.30.70.50.60.6-0.5-0.40.4-0.3
Bone: cortical tissue density0.50.61.21.0-1.0-1.01.01.01.01.00.91.0-1.0-1.10.8-1.0-0.70.70.4-0.7-0.4-0.30.2-0.90.10.00.1-0.1
Condit. Reinf. active minus inactive responses0.80.92.7-0.91.11.1-1.1-1.1-1.1-1.1-1.2-0.61.21.3-0.50.61.1-0.9-0.90.60.80.90.81.7-0.8-0.70.7-0.6
Condit. Reinf. active-inactive response ratio0.40.41.1-0.90.90.9-0.9-0.9-0.9-0.9-0.7-0.60.70.9-0.41.00.4-0.50.00.1-0.1-0.0-0.10.90.20.3-0.30.5
Condit. Reinf. active responses3.13.86.7-1.72.12.1-2.1-2.1-2.1-2.2-2.4-1.52.32.4-1.51.12.3-2.1-2.01.61.92.01.82.6-1.7-1.51.5-1.4
Condit. Reinf. inactive responses4.45.38.3-1.52.02.0-2.0-2.0-2.0-2.1-2.6-1.52.42.4-1.80.52.8-2.6-2.92.22.82.82.72.4-2.7-2.52.4-2.4
Incentive salience index mean0.81.02.9-0.91.11.1-1.1-1.1-1.1-1.1-1.3-0.51.21.4-0.50.61.2-1.0-0.90.40.91.00.91.7-0.9-0.80.8-0.7
Condit. Reinf. lever presses1.01.33.0-0.40.80.8-0.8-0.8-0.8-0.8-1.3-0.31.11.2-0.4-0.11.4-0.9-1.40.61.41.51.71.6-1.5-1.51.5-1.5
Condit. Reinf. active minus inactive responses1.01.33.2-0.60.70.7-0.7-0.8-0.7-0.8-1.4-0.91.61.8-1.10.11.3-0.2-1.51.41.41.40.91.4-1.3-1.21.2-1.4
Condit. Reinf. active-inactive response ratio0.30.32.10.1-0.4-0.40.40.30.40.40.3-0.0-0.10.20.00.1-0.61.50.7-0.1-0.9-0.8-0.9-0.30.70.7-0.70.5
Condit. Reinf. active responses2.94.07.4-0.91.51.5-1.5-1.6-1.5-1.5-2.4-0.82.22.5-1.00.02.4-1.7-2.71.32.72.72.22.5-2.5-2.42.4-2.4
Condit. Reinf. inactive responses6.47.913.6-1.62.42.4-2.4-2.5-2.4-2.5-3.2-1.12.82.9-1.30.53.4-3.6-3.61.43.73.63.43.3-3.4-3.23.1-2.8
Condit. Reinf. lever presses1.62.24.5-1.81.81.8-1.8-1.9-1.8-1.8-1.8-1.71.92.1-1.71.61.5-1.1-1.21.40.80.80.61.7-0.6-0.40.3-0.4
Condit. Reinf. lever reinforcers received2.73.86.8-1.11.51.5-1.5-1.7-1.5-1.6-2.4-0.92.22.5-1.10.22.4-1.7-2.61.32.52.52.12.5-2.4-2.22.2-2.2
Conditioned reinforcement - actives0.80.82.01.3-1.1-1.01.01.01.01.10.61.4-0.8-0.81.3-1.4-0.40.60.1-1.10.10.30.4-0.4-0.5-0.70.8-0.7
Conditioned reinforcement - inactives0.60.61.51.0-1.0-1.01.00.90.91.00.81.2-0.9-0.81.2-0.9-0.70.60.6-1.2-0.4-0.3-0.3-0.50.20.00.00.2
Conditioned locomotion1.82.24.1-0.91.21.2-1.2-1.2-1.3-1.2-1.7-0.81.61.6-0.90.31.8-1.6-2.01.12.01.81.91.6-1.7-1.61.6-1.4
Patch foraging indifference point 0 sec1.82.97.1-2.62.22.4-2.4-2.3-2.4-2.3-1.6-2.31.61.5-2.12.71.3-1.8-0.21.4-0.3-0.0-0.51.20.30.7-0.80.6
Patch foraging indifference point AUC0.50.52.40.20.30.1-0.1-0.2-0.2-0.3-0.40.30.20.00.3-0.50.7-1.5-1.1-0.11.31.11.10.1-1.1-1.11.1-0.8
Delay disc. indifference point, 0s delay0.50.61.70.9-0.7-0.80.80.60.70.70.10.6-0.1-0.20.5-1.20.20.5-0.80.11.00.90.8-0.1-0.9-1.01.1-1.3
Delay disc. indifference point, 16s delay1.01.02.6-1.41.01.1-1.1-1.0-1.1-1.1-0.6-1.60.80.8-1.51.60.2-0.10.51.3-0.9-0.8-0.8-0.00.81.0-1.10.8
Delay disc. indifference point, 2s delay0.50.61.5-1.00.70.7-0.7-0.8-0.7-0.5-0.3-1.20.60.6-1.11.2-0.00.40.61.0-0.9-0.8-0.70.20.80.9-1.00.7
Delay disc. indifference point, 24s delay0.80.72.3-0.1-0.2-0.20.20.30.20.20.8-0.3-0.5-0.6-0.30.5-0.90.81.30.2-1.5-1.4-1.4-0.51.31.3-1.31.1
Delay disc. indifference point, 4s delay0.70.81.7-1.31.11.1-1.1-1.2-1.1-1.1-0.9-1.31.01.0-1.21.30.7-0.7-0.31.00.10.10.00.70.10.2-0.30.2
Delay disc. indifference point, 8s delay0.90.92.6-0.50.10.1-0.1-0.1-0.20.10.4-0.7-0.1-0.2-0.51.0-0.81.01.40.3-1.6-1.6-1.6-0.71.51.5-1.51.4
Indifference point function ln k0.71.03.0-0.70.20.2-0.2-0.2-0.2-0.10.3-0.5-0.10.1-0.41.2-0.81.21.4-0.3-1.6-1.6-1.7-0.61.61.7-1.71.6
Indifference point function log k0.71.03.0-0.70.20.2-0.2-0.2-0.2-0.10.3-0.5-0.10.1-0.41.2-0.81.21.4-0.3-1.6-1.6-1.7-0.61.61.7-1.71.6
Patch foraging total patch changes 0 sec1.52.45.5-2.32.02.1-2.1-2.1-2.2-2.1-1.5-2.01.41.3-1.92.31.2-1.7-0.21.3-0.20.1-0.41.20.20.5-0.60.5
Patch foraging total patch changes 12 sec0.10.10.40.1-0.0-0.20.20.10.2-0.00.40.2-0.5-0.70.20.0-0.4-0.40.6-0.3-0.6-0.5-0.5-0.40.40.4-0.40.4
Patch foraging total patch changes 18 sec0.81.03.9-1.21.31.2-1.2-1.3-1.3-1.3-1.1-0.90.90.7-0.81.01.1-2.0-0.80.50.70.70.30.9-0.5-0.40.3-0.1
Patch foraging total patch changes 24 sec2.73.35.6-2.42.32.3-2.3-2.3-2.2-2.4-2.0-2.31.91.7-2.32.11.8-2.4-1.31.90.90.81.01.2-0.6-0.20.1-0.2
Patch foraging total patch changes 6 sec0.71.04.2-1.41.41.4-1.4-1.4-1.4-1.5-1.0-1.10.70.5-1.01.40.9-2.1-0.30.50.10.3-0.20.6-0.10.1-0.20.4
Patch foraging time to switch 0 sec0.60.92.01.0-0.9-1.11.11.21.11.01.20.9-1.0-1.00.8-0.8-1.11.41.0-0.6-1.0-0.8-0.7-0.50.70.6-0.50.3
Patch foraging water rate 0 sec0.00.10.4-0.0-0.20.0-0.0-0.10.10.10.2-0.1-0.2-0.3-0.00.1-0.2-0.00.40.0-0.5-0.4-0.6-0.20.30.3-0.30.3
Patch foraging water rate 12 sec0.20.30.8-0.00.20.2-0.2-0.3-0.2-0.2-0.6-0.20.50.4-0.2-0.30.7-0.6-0.70.50.70.90.70.6-0.9-0.90.9-0.9
Patch foraging water rate 18 sec0.50.71.0-0.50.50.8-0.8-0.7-0.6-0.6-0.9-0.50.90.9-0.50.11.0-0.8-1.00.81.01.01.01.0-1.0-0.90.9-0.8
Patch foraging water rate 24 sec0.40.61.8-0.60.50.7-0.7-0.5-0.7-0.6-0.6-0.90.60.4-1.00.31.0-0.7-0.81.30.60.80.61.1-0.8-0.70.7-0.9
Patch foraging water rate 6 sec0.10.10.4-0.10.00.1-0.1-0.1-0.1-0.0-0.3-0.30.30.2-0.3-0.10.4-0.2-0.60.60.60.50.50.4-0.5-0.50.5-0.6
Seeking ratio, delayed vs. immediate footshock2.83.35.4-2.32.32.3-2.3-2.3-2.2-2.3-2.0-2.32.12.1-2.32.11.8-2.0-1.32.01.10.90.71.3-0.6-0.30.2-0.1
Distance traveled before self-admin0.30.30.9-0.80.80.8-0.8-0.7-0.7-0.8-0.6-0.70.50.4-0.70.70.6-0.7-0.20.50.10.40.10.9-0.2-0.10.1-0.2
Distance traveled after self-admin2.93.35.1-2.22.32.2-2.2-2.2-2.2-2.2-2.0-2.12.01.9-2.11.92.0-2.1-1.31.91.01.31.31.9-1.0-0.70.5-0.6
Extensor digitorum longus weight3.513.822.6-4.64.74.7-4.7-4.8-4.7-4.7-4.4-4.54.44.4-4.34.13.8-4.0-2.53.81.92.02.63.0-1.5-0.90.6-0.5
Bone: elastic displacement2.02.26.2-0.1-0.6-0.50.50.50.50.61.20.3-1.2-1.10.70.9-1.71.12.2-1.5-2.2-2.3-1.9-1.62.32.3-2.32.5
Bone: elastic work2.73.55.31.1-1.5-1.51.51.51.51.62.11.4-2.0-1.91.7-0.2-2.31.82.3-2.2-2.2-2.3-1.9-2.12.32.1-2.12.3
Bone: endosteal estimation2.55.58.1-2.22.62.5-2.5-2.6-2.5-2.6-2.8-2.42.82.8-2.51.52.7-2.5-2.52.72.22.11.82.3-1.9-1.61.5-1.6
Bone: endosteal perimeter1.63.35.5-1.01.61.5-1.5-1.5-1.5-1.6-2.0-1.22.02.0-1.30.32.1-2.0-2.31.82.32.22.12.1-2.1-2.01.9-1.9
Epididymis fat weight2.25.07.6-2.02.32.5-2.5-2.3-2.5-2.4-2.7-1.72.52.6-1.81.32.8-2.5-2.31.72.22.32.62.3-2.1-1.91.7-1.6
Delta time in closed arm before/after self-admin0.60.61.3-0.70.80.7-0.7-0.7-0.7-0.8-0.9-0.70.80.7-0.70.40.9-0.7-0.70.90.60.80.81.1-0.6-0.50.5-0.7
Delta time in open arm before/after self-admin0.80.82.20.6-0.9-0.80.80.80.80.90.90.5-0.7-0.50.5-0.3-1.11.51.1-0.6-1.1-1.2-1.2-0.91.00.9-0.90.9
Diff in mean of infusions in LGA sessions1.01.12.9-1.41.31.3-1.3-1.3-1.2-1.2-1.0-1.71.21.2-1.61.40.7-0.3-0.11.5-0.2-0.00.10.60.20.4-0.40.2
Delay discount exponential model param1.21.23.11.4-1.0-1.01.01.01.00.90.31.6-0.7-0.61.4-1.80.1-0.2-1.0-1.11.31.31.2-0.0-1.2-1.41.5-1.3
Extinction: sum of active levers before priming0.40.41.8-0.50.50.4-0.4-0.4-0.4-0.4-0.6-0.90.90.9-0.90.20.60.3-0.51.40.30.60.60.9-0.5-0.40.4-0.8
Active lever presses in extinction session 60.20.21.6-0.40.20.3-0.3-0.3-0.3-0.2-0.4-0.80.70.7-0.90.30.30.5-0.31.30.10.20.10.5-0.1-0.00.1-0.4
Bone: final force1.11.83.1-1.51.71.6-1.6-1.6-1.6-1.7-1.6-1.21.61.6-1.21.21.5-1.8-1.21.01.11.10.71.6-0.9-0.70.6-0.4
Bone: final moment1.11.73.0-1.61.71.7-1.7-1.7-1.7-1.7-1.5-1.41.51.6-1.31.41.4-1.7-1.01.00.80.80.61.3-0.6-0.40.3-0.1
Food consumed during 24 hour testing period0.91.12.5-1.51.31.3-1.3-1.3-1.3-1.3-1.2-1.51.31.3-1.61.41.0-0.7-0.71.30.40.3-0.00.7-0.10.1-0.1-0.1
Glucose0.30.42.30.7-0.6-0.60.60.60.60.60.41.2-0.6-0.41.2-0.7-0.40.40.2-1.50.00.00.2-0.3-0.1-0.20.2-0.1
Heart weight0.81.25.7-1.10.91.1-1.1-1.0-1.1-1.0-1.0-1.81.41.3-1.90.91.0-0.4-0.92.40.60.41.00.5-0.4-0.20.2-0.6
Delay discount hyperbolic model param1.01.12.61.3-0.9-0.90.90.90.90.80.31.5-0.6-0.61.3-1.60.1-0.3-0.9-1.11.31.21.2-0.0-1.2-1.41.4-1.2
Intermittent access intake day 1-15 change2.01.95.12.1-1.9-1.81.81.71.71.81.21.9-1.4-1.41.9-2.3-0.71.0-0.1-1.20.40.50.4-0.6-0.6-0.91.1-1.1
Intermittent access intake escalation1.71.64.01.9-1.8-1.71.71.61.61.71.21.7-1.3-1.31.7-2.0-0.81.10.2-1.10.10.20.1-0.6-0.4-0.60.7-0.8
Intermittent access intake escalation 20.30.30.80.7-0.5-0.50.50.50.50.50.20.7-0.3-0.40.7-0.90.00.1-0.2-0.50.30.50.6-0.1-0.6-0.70.7-0.7
Intermitt. access day 1 inactive lever presses0.20.20.60.5-0.2-0.50.50.30.50.20.10.7-0.3-0.30.8-0.5-0.1-0.2-0.1-0.80.30.50.30.2-0.3-0.40.4-0.3
Intermitt. access day 15 inactive lever presses1.11.23.21.6-1.2-1.51.51.31.41.10.81.8-1.0-1.01.7-1.7-0.60.50.2-1.50.20.50.4-0.1-0.5-0.80.8-0.7
Intermitt. access escalation Index0.00.00.20.10.1-0.10.10.00.10.0-0.10.00.20.2-0.0-0.10.0-0.2-0.30.10.4-0.00.10.1-0.1-0.10.10.0
Intermittent access day 1 total infusions0.91.13.51.6-1.3-1.11.11.31.21.20.61.5-0.7-0.61.3-1.9-0.30.9-0.2-0.60.40.60.7-0.5-0.8-1.11.2-1.2
Intermittent access day 15 total infusions1.82.06.32.1-1.8-1.71.71.71.71.70.91.9-1.0-1.01.7-2.5-0.41.0-0.4-0.80.81.01.0-0.3-1.2-1.51.6-1.7
Intermittent access terminal intake (last 3 days)2.32.57.72.2-1.7-1.71.71.71.61.60.72.0-0.9-0.91.8-2.8-0.10.7-0.8-0.81.21.41.5-0.2-1.6-2.02.1-2.2
Intermittent access total infusions1.61.85.01.6-1.1-1.11.11.11.11.00.11.5-0.3-0.31.4-2.20.40.2-1.1-0.41.41.71.7-0.0-1.8-2.12.2-2.2
Intermittent access day 1 locomotion0.50.60.9-0.60.70.8-0.8-0.7-0.8-0.7-0.9-0.60.91.0-0.60.30.9-0.7-0.80.80.70.80.90.8-0.7-0.70.6-0.6
Intermittent access day 15 total locomotion1.11.12.1-1.01.01.2-1.2-1.1-1.2-1.0-1.2-0.91.11.0-0.80.61.3-1.5-1.10.91.01.21.21.3-1.0-0.90.9-0.8
Intermittent access total locomotion1.61.83.1-1.01.21.3-1.3-1.2-1.3-1.2-1.5-0.91.41.4-0.80.51.7-1.8-1.51.01.51.61.61.5-1.5-1.31.3-1.1
Intermittent access standard deviation0.70.71.31.1-1.1-1.11.11.01.11.01.01.1-1.0-1.11.1-1.0-0.80.80.8-0.8-0.7-0.4-0.3-0.40.20.00.0-0.1
Left kidney weight0.10.30.8-0.70.60.7-0.7-0.6-0.6-0.5-0.3-0.80.40.3-0.90.70.3-0.20.10.8-0.3-0.20.00.10.20.3-0.30.1
Right kidney weight0.51.42.8-1.51.61.7-1.7-1.5-1.4-1.5-1.2-1.61.31.2-1.71.31.1-1.2-0.51.50.20.40.80.7-0.3-0.10.0-0.2
Cocaine induced anxiety3.54.06.1-2.42.32.3-2.3-2.3-2.3-2.3-2.4-2.42.52.5-2.41.92.2-1.9-1.92.31.61.51.51.7-1.2-0.80.7-0.8
Post-drug Anxiety2.22.43.5-1.61.71.6-1.6-1.7-1.7-1.7-1.9-1.51.81.9-1.51.21.8-1.7-1.81.31.71.51.51.6-1.2-1.00.9-0.8
Baseline Anxiety1.41.42.50.9-1.0-1.01.01.01.01.01.41.1-1.4-1.41.2-0.4-1.50.71.4-1.6-1.3-1.5-1.5-0.91.31.2-1.21.4
Tail length0.10.20.7-0.20.00.2-0.20.0-0.2-0.10.3-0.2-0.2-0.3-0.10.5-0.4-0.10.50.1-0.5-0.7-0.8-0.40.70.7-0.70.8
Length with tail0.41.42.7-1.61.41.6-1.6-1.4-1.5-1.5-1.3-1.61.51.5-1.61.51.0-0.7-0.51.60.30.30.21.1-0.10.1-0.20.1
Length without tail2.04.47.8-2.42.42.6-2.6-2.5-2.4-2.5-2.5-2.52.72.8-2.62.02.2-1.5-1.52.61.21.41.42.3-1.1-0.80.7-0.9
Times rat made contact with spout0.30.30.7-0.50.60.6-0.6-0.6-0.6-0.6-0.6-0.30.50.5-0.30.40.6-0.8-0.70.10.60.60.80.7-0.4-0.30.3-0.3
Lifetime Intake1.71.95.61.7-1.2-1.21.21.21.21.10.21.6-0.4-0.41.4-2.40.30.4-1.0-0.51.31.61.7-0.1-1.8-2.12.2-2.3
Liver weight, left0.00.00.3-0.10.20.2-0.2-0.2-0.2-0.1-0.20.10.10.20.00.10.2-0.3-0.2-0.30.30.20.6-0.1-0.2-0.10.1-0.0
Liver weight, right0.10.20.90.6-0.3-0.50.50.40.40.30.40.8-0.6-0.70.8-0.5-0.2-0.40.1-1.00.10.20.3-0.3-0.1-0.20.20.0
Locomotor activity0.20.41.21.0-0.8-0.70.70.70.80.70.31.0-0.4-0.21.1-1.0-0.30.4-0.2-0.80.40.30.1-0.1-0.3-0.50.5-0.3
Locomotor testing distance1.52.64.3-1.01.31.5-1.5-1.4-1.4-1.3-2.0-0.91.92.0-1.00.41.9-1.5-2.11.32.12.11.81.7-1.8-1.71.7-1.6
Locomotor testing rearing0.10.10.40.5-0.4-0.20.20.20.30.4-0.00.5-0.1-0.10.5-0.60.0-0.1-0.3-0.40.40.50.7-0.2-0.4-0.50.5-0.4
Locomotion in novel chamber2.02.44.0-2.01.91.9-1.9-1.9-1.9-1.9-1.9-1.81.92.0-1.81.71.6-1.5-1.31.51.00.90.91.3-0.7-0.40.3-0.2
Locomotion in novel chamber post-restriction0.10.10.20.3-0.4-0.40.40.40.20.40.40.5-0.4-0.40.4-0.3-0.30.40.2-0.5-0.1-0.3-0.2-0.40.20.2-0.10.2
Fecal boli incidents, locomotor time 11.71.83.71.6-1.5-1.51.51.51.51.51.51.8-1.5-1.41.9-1.3-1.41.41.2-1.9-1.0-0.9-1.2-1.00.70.5-0.40.5
Change in fecal boli incidents, locomotor task1.01.01.9-0.80.90.9-0.9-0.9-1.0-1.0-1.1-0.91.00.8-1.00.51.3-1.4-1.21.11.11.11.00.7-1.0-0.90.9-0.9
Time >=10cm from walls, locomotor time 10.10.10.40.5-0.3-0.30.30.60.30.10.30.5-0.3-0.30.4-0.6-0.0-0.1-0.4-0.00.50.50.30.1-0.4-0.50.5-0.5
Bouts of movement, locomotor time 10.40.51.00.8-0.7-0.80.81.00.70.61.00.9-0.9-0.90.9-0.6-0.70.50.5-0.7-0.4-0.4-0.5-0.30.40.3-0.20.3
Total resting periods, locomotor time 11.31.42.41.2-1.3-1.41.41.41.31.21.61.3-1.4-1.41.3-0.8-1.41.31.2-1.2-1.1-1.1-1.3-0.71.00.8-0.80.8
Rest time, locomotor task time 10.60.72.31.0-1.0-1.01.00.91.11.00.80.8-0.7-0.50.8-0.8-1.01.50.7-0.9-0.6-0.7-0.9-0.60.60.5-0.40.4
Distance moved, locomotor task time 11.92.13.3-1.61.61.5-1.5-1.6-1.7-1.6-1.6-1.71.51.3-1.71.21.7-1.8-1.41.81.21.21.41.3-1.0-0.80.7-0.8
Vertical activity count, locomotor time 12.02.14.9-1.91.91.7-1.7-1.9-1.9-1.8-1.6-1.71.51.2-1.61.61.6-2.2-1.11.40.90.91.10.9-0.7-0.40.3-0.2
Time >=10cm from walls, locomotor time 20.30.30.90.8-0.7-0.80.80.90.80.60.70.5-0.5-0.50.3-0.9-0.40.7-0.30.30.30.20.2-0.3-0.2-0.30.3-0.5
Bouts of movement, locomotor time 22.42.64.22.0-2.1-1.91.91.92.02.01.91.9-1.9-1.91.8-1.7-1.81.61.2-1.7-0.9-1.0-1.2-1.50.80.5-0.40.5
Total resting periods, locomotor time 21.92.13.51.8-1.8-1.61.61.61.71.71.71.8-1.8-1.71.8-1.4-1.61.31.1-1.9-0.9-0.9-1.1-1.20.80.5-0.50.6
Rest time, locomotor task time 20.20.20.70.20.0-0.10.10.20.30.20.40.4-0.4-0.40.50.1-0.50.20.6-0.8-0.5-0.5-0.8-0.60.60.5-0.50.7
Distance moved, locomotor task time 21.41.74.3-1.11.00.9-0.9-1.1-1.1-1.0-1.4-1.51.61.5-1.60.61.5-0.8-1.62.11.41.41.71.0-1.2-1.01.0-1.2
Vertical activity count, locomotor time 21.31.43.2-0.60.80.7-0.7-0.8-0.9-0.9-1.2-0.81.21.2-1.00.11.4-1.1-1.71.51.61.61.80.6-1.5-1.41.4-1.5
Light reinforcement 10.61.02.41.4-1.4-1.61.61.21.41.31.01.1-0.9-0.81.0-1.3-1.01.40.5-0.7-0.4-0.4-0.1-1.20.30.1-0.0-0.1
Light reinforcement 20.20.30.70.8-0.6-0.80.80.70.80.60.60.7-0.6-0.50.6-0.7-0.60.70.5-0.4-0.5-0.3-0.3-0.30.20.1-0.1-0.1
Bone: marrow area2.75.88.4-2.42.72.6-2.6-2.7-2.6-2.7-2.8-2.62.92.9-2.71.72.7-2.6-2.42.82.22.11.82.3-1.8-1.51.4-1.5
Bone: maximum diameter1.22.13.5-1.31.51.5-1.5-1.5-1.5-1.6-1.6-1.31.61.5-1.40.81.7-1.9-1.71.61.61.51.61.6-1.3-1.11.0-1.0
Bone: maximum force0.30.61.0-0.91.01.0-1.0-1.0-1.0-1.0-0.9-0.70.91.0-0.70.80.8-1.0-0.60.50.50.50.30.8-0.3-0.20.2-0.0
Bone: maximum moment0.30.61.1-1.01.01.0-1.0-1.0-1.0-1.0-0.8-0.80.80.9-0.71.00.6-0.9-0.40.40.30.20.10.5-0.00.1-0.20.3
Mean time between licks in bursts0.10.10.50.1-0.1-0.10.10.30.10.10.30.3-0.3-0.20.20.0-0.30.30.5-0.5-0.4-0.40.1-0.70.30.3-0.30.3
Mean num. licks in bursts1.21.53.41.5-1.5-1.51.51.51.51.51.31.7-1.4-1.31.8-1.3-1.21.10.7-1.7-0.4-0.5-0.4-0.70.40.2-0.10.3
Cd content in liver0.91.02.71.5-1.2-1.21.21.21.21.10.71.6-0.9-0.81.5-1.6-0.50.50.0-1.20.30.30.6-0.3-0.5-0.80.8-0.7
Co content in liver0.50.61.0-0.70.80.8-0.8-0.8-0.8-0.8-0.9-0.60.91.0-0.60.50.8-0.8-0.70.60.70.71.00.9-0.6-0.50.5-0.4
Cu content in liver0.60.71.4-0.91.00.8-0.8-1.0-0.8-0.9-1.0-1.01.11.1-1.10.60.9-0.7-0.81.20.70.60.90.8-0.5-0.40.4-0.4
Fe content in liver0.70.91.70.7-0.9-0.90.90.90.90.91.00.9-1.0-0.81.1-0.3-1.11.11.1-1.3-1.0-1.1-1.0-0.61.00.9-0.91.0
K content in liver1.01.01.80.9-1.0-1.11.11.11.11.11.30.8-1.2-1.30.9-0.6-1.21.11.1-0.9-1.0-1.0-0.9-1.10.90.8-0.80.7
Mg content in liver1.61.63.20.9-1.3-1.31.31.31.31.31.50.7-1.4-1.40.8-0.5-1.51.81.5-0.8-1.5-1.4-1.3-1.41.41.3-1.21.0
Mn content in liver2.12.43.61.3-1.6-1.61.61.61.61.61.91.4-1.9-1.91.5-0.8-1.81.61.7-1.7-1.5-1.5-1.6-1.71.41.3-1.21.2
Na content in liver0.40.51.5-0.60.80.7-0.7-0.7-0.7-0.8-0.7-0.50.60.4-0.50.30.8-1.2-0.80.50.70.70.80.6-0.7-0.60.6-0.5
Rb content in liver0.10.20.5-0.30.2-0.00.0-0.10.0-0.10.1-0.30.00.1-0.20.5-0.30.40.5-0.0-0.6-0.6-0.6-0.10.70.7-0.70.6
Se content in liver1.92.36.92.3-1.9-1.81.81.81.81.81.02.3-1.2-1.12.0-2.6-0.51.0-0.3-1.50.70.71.0-0.5-1.1-1.41.5-1.5
Sr content in liver0.60.51.70.20.10.2-0.2-0.2-0.2-0.1-0.6-0.10.60.5-0.3-0.60.8-0.3-0.90.80.90.91.10.7-1.1-1.21.2-1.3
Zn content in liver1.01.12.60.0-0.5-0.50.50.50.50.50.9-0.1-0.6-0.6-0.00.5-1.21.51.4-0.3-1.6-1.6-1.3-1.21.61.6-1.61.4
Bone: minimum diameter1.83.45.3-1.92.22.1-2.1-2.2-2.1-2.2-2.2-2.02.32.3-1.91.52.0-2.0-1.71.91.51.51.42.0-1.2-0.90.8-0.8
Time in familiar zone, hab. session 10.20.20.60.10.00.0-0.0-0.0-0.0-0.1-0.30.10.30.30.0-0.30.4-0.2-0.60.10.70.60.80.4-0.6-0.60.6-0.6
Time in novel zone, hab. session 10.10.10.20.3-0.3-0.30.30.30.30.30.30.1-0.3-0.50.1-0.3-0.10.10.10.2-0.1-0.0-0.2-0.1-0.0-0.10.1-0.2
Total zone transitions, hab. session 11.21.62.6-1.61.61.6-1.6-1.6-1.6-1.6-1.5-1.61.61.6-1.61.41.3-1.2-1.11.50.80.80.61.3-0.5-0.30.2-0.3
Total locomotion distance, hab. session 11.01.43.8-0.91.11.1-1.1-1.1-1.1-1.1-1.3-1.31.41.2-1.50.51.3-1.0-1.41.91.21.21.21.0-1.1-0.90.9-1.1
Locomotion velocity, hab. session 10.91.33.7-1.11.21.2-1.2-1.2-1.2-1.2-1.2-1.51.41.3-1.60.81.2-1.0-1.11.90.91.01.00.7-0.8-0.60.6-0.8
Time in familiar zone, hab. session 23.13.25.52.3-2.3-2.32.32.32.32.32.12.2-2.1-2.22.2-2.1-1.81.71.3-1.8-0.9-0.9-0.4-1.60.60.3-0.20.3
Time in novel zone, hab. session 22.82.85.7-2.22.12.1-2.1-2.1-2.1-2.1-1.9-2.32.01.9-2.42.01.6-1.4-1.12.10.70.70.21.3-0.4-0.1-0.0-0.2
Total zone transitions, hab. session 22.83.65.3-1.62.02.0-2.0-2.0-2.0-2.0-2.3-1.52.12.1-1.61.02.3-2.2-2.11.72.02.01.92.1-1.8-1.61.5-1.5
Total locomotion distance, hab. session 21.62.13.2-1.01.41.3-1.3-1.3-1.3-1.4-1.7-1.11.71.7-1.30.51.7-1.5-1.81.61.71.71.81.3-1.5-1.41.4-1.4
Locomotion velocity, hab. session 22.22.94.8-1.11.51.5-1.5-1.5-1.5-1.5-2.0-1.21.91.9-1.40.42.0-1.8-2.11.82.02.12.21.5-1.9-1.81.7-1.7
Novel to familiar place preference ratio1.31.34.0-0.70.10.1-0.1-0.1-0.1-0.00.7-0.7-0.5-0.6-0.61.3-1.00.81.5-0.1-1.8-1.7-1.8-1.11.92.0-2.01.8
Novelty place preference1.61.64.8-0.70.00.1-0.1-0.1-0.1-0.00.8-0.7-0.6-0.7-0.61.3-1.10.91.7-0.1-2.0-1.9-2.0-1.22.02.2-2.22.0
Time in novel zone, NPP test1.61.65.0-1.00.40.4-0.4-0.4-0.4-0.30.5-0.9-0.4-0.5-0.81.7-0.90.51.6-0.1-2.0-1.8-1.9-1.02.02.2-2.22.0
Total zone transitions, NPP test1.52.25.1-0.10.70.6-0.6-0.6-0.6-0.7-1.4-0.21.31.3-0.4-0.71.7-1.3-2.11.12.22.32.01.6-2.2-2.22.2-2.2
Total locomotion distance, NPP test1.21.64.10.30.30.3-0.3-0.3-0.3-0.3-1.00.00.90.9-0.2-0.91.3-0.9-1.81.01.92.02.01.1-2.0-2.02.0-2.0
Locomotion velocity, NPP test1.11.54.50.7-0.1-0.10.10.10.10.1-0.70.30.70.70.1-1.41.1-0.6-1.70.91.92.02.00.9-2.0-2.12.1-2.1
Intraocular pressure0.60.92.71.2-1.4-1.21.21.31.31.31.00.9-0.8-0.70.7-1.2-0.91.60.6-0.2-0.5-0.3-0.7-0.50.20.10.0-0.3
Delta distance traveled before/after self-admin0.70.71.9-1.01.11.0-1.0-1.1-1.1-1.1-1.0-0.80.90.9-0.70.91.0-1.4-0.70.50.70.60.60.6-0.5-0.40.3-0.1
Delta ambulatory time before/after self-admin0.50.51.3-0.80.90.8-0.8-0.9-0.9-0.8-0.8-0.80.80.7-0.70.70.8-1.1-0.70.60.70.60.60.4-0.5-0.30.3-0.1
Parametrial fat weight0.61.22.1-0.81.01.1-1.1-1.0-1.0-1.2-1.3-0.81.11.1-0.90.41.3-1.4-1.31.01.31.31.01.0-1.2-1.11.0-1.0
Pavlov. Cond. lever latency1.01.32.30.4-0.8-0.80.80.80.80.81.30.5-1.2-1.30.60.1-1.40.91.5-1.0-1.4-1.5-1.4-1.41.51.4-1.41.4
Pavlov. Cond. magazine entry latency2.32.95.9-1.92.01.9-1.9-1.9-1.9-2.0-2.0-2.12.22.1-2.21.41.9-1.4-1.52.41.11.21.11.6-1.0-0.80.7-0.9
Pavlov. Cond. change in total contacts0.80.81.6-0.50.80.8-0.8-0.8-0.8-0.8-1.0-0.30.91.0-0.40.11.1-1.0-1.20.51.11.21.31.1-1.1-1.11.0-1.0
Pavlov. Cond. index score3.03.95.6-1.51.91.9-1.9-1.9-1.9-1.9-2.3-1.52.32.3-1.70.72.4-1.9-2.32.02.12.22.12.2-2.1-1.91.8-1.9
Pavlov. Cond. latency score2.63.34.9-1.21.61.6-1.6-1.6-1.6-1.7-2.1-1.22.02.1-1.40.42.2-1.8-2.21.72.12.22.12.1-2.1-1.91.9-1.9
Pavlov. Cond. lever contacts1.72.03.8-0.71.11.1-1.1-1.1-1.1-1.1-1.6-0.61.51.6-0.80.01.7-1.2-1.81.01.81.92.01.7-1.8-1.71.7-1.7
Pavlov. Cond. magazine entry number3.84.76.62.4-2.6-2.52.52.52.52.52.62.4-2.6-2.52.5-1.8-2.52.22.0-2.5-1.6-1.7-1.5-2.21.41.1-1.01.2
Pavlov. Cond. intertrial magazine entries0.70.81.91.0-1.2-1.11.11.11.11.11.10.8-1.0-0.90.8-0.8-1.01.40.8-0.6-0.7-0.6-0.7-0.80.60.4-0.40.3
Pavlov. Cond. lever-magazine prob. diff.3.03.75.4-1.51.91.9-1.9-1.9-1.9-1.9-2.3-1.62.22.2-1.70.82.3-1.9-2.22.02.02.12.12.1-1.9-1.71.7-1.8
Pavlov. Cond. response bias3.34.05.9-2.02.22.2-2.2-2.2-2.2-2.2-2.4-2.12.42.4-2.31.52.3-1.8-2.02.41.61.71.82.0-1.5-1.21.1-1.4
Pavlov. Cond. lever latency3.34.57.02.4-2.5-2.52.52.62.52.52.62.2-2.6-2.62.2-1.9-2.42.22.0-1.8-1.6-1.6-1.4-2.31.31.0-0.90.9
Pavlov. Cond. magazine entry latency1.41.75.3-2.01.71.7-1.7-1.7-1.7-1.6-1.0-1.51.01.1-1.32.30.6-1.10.30.2-0.6-0.6-0.70.40.81.1-1.21.3
Pavlov. Cond. change in total contacts3.75.19.4-2.42.62.6-2.6-2.7-2.6-2.6-2.8-2.22.93.1-2.21.82.6-2.2-2.21.91.91.81.72.5-1.6-1.31.1-1.1
Pavlov. Cond. index score4.76.010.6-3.23.23.2-3.2-3.3-3.2-3.1-2.9-2.72.93.0-2.62.82.6-2.6-1.71.91.31.31.12.4-1.0-0.50.4-0.3
Pavlov. Cond. latency score4.25.29.2-3.02.92.9-2.9-3.0-2.9-2.9-2.7-2.62.72.8-2.52.62.4-2.4-1.61.81.21.20.92.3-0.9-0.50.3-0.3
Pavlov. Cond. lever contacts3.64.97.5-2.52.62.6-2.6-2.7-2.6-2.6-2.7-2.22.62.7-2.31.92.5-2.4-2.01.91.71.71.62.5-1.5-1.11.0-1.1
Pavlov. Cond. magazine entry number3.74.59.73.1-2.9-2.92.93.02.92.82.32.6-2.3-2.42.5-3.1-1.82.10.9-1.4-0.4-0.3-0.3-1.60.0-0.40.6-0.6
Pavlov. Cond. intertrial magazine entries0.20.30.80.20.10.1-0.1-0.1-0.1-0.1-0.40.10.30.20.1-0.50.5-0.6-0.80.30.90.80.70.6-0.8-0.90.9-0.8
Pavlov. Cond. lever-magazine prob. diff.4.55.89.9-3.03.03.0-3.0-3.1-3.0-3.0-2.9-2.62.83.0-2.52.62.6-2.6-1.81.91.41.41.22.5-1.1-0.70.5-0.5
Pavlov. Cond. response bias3.14.27.6-2.62.62.6-2.6-2.8-2.6-2.6-2.5-2.32.42.5-2.22.32.2-2.2-1.51.61.11.11.02.1-0.9-0.50.4-0.4
Time in closed arm before self-admin0.50.61.01.0-1.0-1.01.00.90.90.90.90.9-0.9-0.90.9-0.9-0.70.70.3-0.8-0.2-0.4-0.3-0.80.20.1-0.00.1
Time in closed arm after self-admin0.30.31.00.9-0.8-0.70.70.70.80.80.40.6-0.4-0.40.6-1.0-0.30.90.0-0.10.00.20.10.0-0.3-0.40.5-0.7
Time in open arm before self-admin3.13.36.5-2.62.52.5-2.5-2.5-2.4-2.4-2.0-2.21.91.8-2.02.51.6-2.4-0.81.50.50.50.21.4-0.20.2-0.30.5
Time in open arm after self-admin0.40.51.3-1.00.90.9-0.9-0.9-0.9-0.9-0.6-0.90.70.8-0.81.10.3-0.40.30.5-0.4-0.2-0.30.60.40.5-0.60.6
Bone: periosteal estimation1.94.05.8-2.12.32.2-2.2-2.3-2.2-2.3-2.3-2.22.42.4-2.21.52.2-2.2-2.02.31.71.61.52.0-1.4-1.11.0-1.0
Bone: periosteal perimeter0.71.12.2-0.30.80.7-0.7-0.7-0.7-0.8-1.1-0.41.01.0-0.4-0.11.2-1.3-1.40.81.51.51.51.4-1.4-1.41.3-1.3
Bone: post-yield work0.40.61.5-0.60.70.7-0.7-0.7-0.7-0.7-1.0-0.71.11.2-0.80.30.9-0.2-0.61.00.50.81.10.8-0.7-0.60.6-0.8
Progressive ratio test 1 active lever presses1.31.43.80.20.10.4-0.4-0.1-0.3-0.2-0.90.20.70.70.0-0.91.3-0.8-1.70.61.91.91.90.7-1.9-1.92.0-1.9
Progressive ratio test 1 breakpoint1.51.64.40.20.10.4-0.4-0.1-0.3-0.2-0.90.20.80.80.0-0.91.4-0.9-1.90.62.02.02.00.7-2.0-2.12.1-2.1
Progressive ratio test 1 inactive lever presses1.21.33.41.2-0.7-0.70.70.70.70.7-0.01.5-0.3-0.31.3-1.70.5-0.2-1.0-0.81.31.61.50.0-1.6-1.81.8-1.8
Progressive ratio test 2 active lever presses1.31.44.41.4-1.0-0.80.81.00.80.90.11.1-0.1-0.20.8-1.90.40.5-1.10.21.31.41.60.4-1.6-1.81.9-2.1
Progressive ratio test 2 breakpoint1.31.44.91.1-0.8-0.50.50.70.60.7-0.20.80.1-0.00.6-1.80.70.1-1.40.41.61.71.80.5-1.8-2.02.1-2.2
Progressive ratio test 2 inactive lever presses1.31.54.41.7-1.3-1.31.31.21.31.30.41.7-0.6-0.61.6-2.1-0.00.7-0.6-0.80.91.11.2-0.0-1.3-1.51.6-1.7
Incentive Sensitization - Responses0.70.72.50.5-0.3-0.30.30.30.10.3-0.30.20.30.20.0-1.00.60.1-1.10.71.21.21.31.0-1.3-1.31.4-1.6
Incentive Sensitization - Breakpoint0.70.72.60.6-0.4-0.40.40.40.30.4-0.20.30.30.20.1-1.10.60.2-1.10.71.21.21.30.9-1.3-1.41.4-1.6
Sum of active levers in priming session hrs 5-60.50.51.80.6-0.3-0.40.40.40.40.3-0.20.00.50.6-0.2-1.00.40.7-1.00.91.01.01.10.3-0.9-1.01.1-1.3
Progressive ratio0.40.41.40.2-0.0-0.10.10.10.2-0.0-0.4-0.30.50.5-0.4-0.60.5-0.1-1.01.21.00.91.00.7-0.9-0.91.0-1.1
Food seeking constrained by brief footshock1.31.63.8-1.61.61.5-1.5-1.4-1.6-1.5-1.3-1.81.51.5-2.01.51.1-0.6-0.71.90.40.30.60.6-0.10.1-0.2-0.1
Seeking ratio, punishment vs. effort0.60.72.2-1.20.90.9-0.9-0.8-1.1-0.8-0.3-0.90.30.4-0.81.50.0-0.00.60.1-0.8-0.8-0.7-0.40.91.1-1.21.1
Retroperitoneal fat weight1.75.58.8-1.62.22.2-2.2-2.1-2.1-2.2-2.7-1.42.42.4-1.70.72.9-2.8-2.91.92.92.83.02.3-2.6-2.42.3-2.2
Reaction time number correct1.42.05.31.5-1.0-1.01.00.81.00.8-0.11.3-0.1-0.01.1-2.20.6-0.3-1.9-0.32.31.91.80.7-2.0-2.22.3-2.2
Reaction time mean minus median2.43.29.7-2.52.12.0-2.0-2.0-2.0-1.9-1.1-2.11.31.5-1.83.10.3-0.51.40.6-1.9-1.6-1.10.21.62.0-2.12.2
Reaction time mean minus median AUC1.62.06.3-2.11.71.7-1.7-1.7-1.7-1.6-0.9-1.71.01.1-1.52.50.4-0.61.00.5-1.4-1.1-0.80.11.21.5-1.61.6
Reaction time num false alarms0.00.00.10.1-0.0-0.20.20.10.10.10.0-0.00.00.1-0.1-0.1-0.10.2-0.20.10.30.2-0.1-0.20.00.00.0-0.1
Reaction time num false alarms AUC0.10.10.30.4-0.2-0.30.30.20.20.20.10.3-0.1-0.10.2-0.5-0.00.1-0.4-0.10.50.40.1-0.1-0.3-0.30.3-0.4
Reaction time trials correct on left1.42.05.31.5-1.0-1.01.00.81.00.8-0.11.3-0.1-0.01.1-2.20.6-0.3-1.9-0.32.31.91.80.7-2.0-2.22.3-2.2
Reaction time trials on left1.31.84.71.5-1.0-1.01.00.80.90.8-0.11.3-0.1-0.01.1-2.10.5-0.2-1.8-0.32.21.81.70.7-1.9-2.12.2-2.0
Reaction time mean1.52.15.1-1.61.21.1-1.1-1.2-1.1-1.1-0.4-1.40.71.0-1.12.3-0.40.61.90.2-2.3-1.8-1.6-0.31.82.1-2.22.1
Reaction time mean AUC1.72.26.2-1.51.11.0-1.0-1.0-1.0-1.0-0.2-1.30.50.7-1.02.3-0.60.72.10.0-2.5-2.0-1.7-0.52.02.3-2.42.4
Median of all reaction times1.11.55.0-0.80.50.4-0.4-0.5-0.4-0.40.2-0.80.20.4-0.51.5-0.81.12.0-0.1-2.2-1.7-1.7-0.61.81.9-2.01.9
Reaction time omissions2.33.18.9-1.40.80.5-0.5-0.7-0.5-0.50.3-1.60.30.5-1.22.3-1.21.62.50.4-2.8-2.7-2.3-0.92.72.9-3.02.9
Reaction time false alarm rate0.10.10.4-0.40.40.2-0.2-0.2-0.3-0.30.0-0.40.10.1-0.40.5-0.10.10.20.3-0.4-0.3-0.6-0.30.50.6-0.60.5
Reaction time premature initiation rate3.85.07.72.5-2.5-2.52.52.42.62.42.72.3-2.6-2.62.5-1.8-2.82.02.0-2.3-1.7-2.0-2.0-2.31.81.5-1.31.5
Reaction time premature initiations3.04.28.73.0-2.7-2.72.72.52.82.52.32.8-2.3-2.32.8-2.7-2.11.50.8-2.2-0.3-0.7-0.8-1.50.50.10.10.2
Std. dev. reaction times2.83.911.3-2.82.32.2-2.2-2.2-2.2-2.1-1.2-2.61.61.8-2.33.40.4-0.21.41.2-2.0-1.6-1.30.21.72.1-2.32.2
Reaction time trials completed1.31.84.71.5-1.0-1.01.00.80.90.8-0.11.3-0.1-0.01.1-2.10.5-0.2-1.8-0.32.21.81.70.7-1.9-2.12.2-2.0
Reaction time trials AUC1.31.94.91.4-1.0-1.01.00.80.90.8-0.11.3-0.1-0.01.1-2.10.6-0.3-1.8-0.32.21.81.70.7-1.9-2.12.2-2.1
Run reversals in cocaine runway, females1.01.02.5-0.40.70.7-0.7-0.7-0.7-0.8-0.9-0.10.70.6-0.0-0.01.2-1.5-1.30.21.41.51.61.4-1.3-1.31.2-1.1
Run reversals in cocaine runway, males0.70.61.1-0.70.80.9-0.9-0.8-0.9-0.9-1.0-0.30.80.8-0.40.51.0-1.1-0.80.30.81.00.80.8-0.8-0.80.7-0.7
Latency to leave start box in cocaine runway0.40.41.7-0.50.30.3-0.3-0.3-0.4-0.30.2-0.1-0.2-0.10.00.9-0.4-0.20.7-0.8-0.7-0.9-1.10.60.91.0-1.01.3
Latency to leave start box in cocaine runway, F0.40.41.6-0.0-0.1-0.10.10.10.00.10.50.4-0.6-0.50.60.4-0.6-0.30.6-1.3-0.5-0.8-1.20.20.80.8-0.81.2
Latency to leave start box in cocaine runway, M0.40.31.0-0.0-0.2-0.20.20.20.20.30.5-0.0-0.4-0.30.10.3-0.60.81.0-0.4-1.0-0.9-1.0-0.10.90.9-0.90.8
Std. dev. time between licks in bursts0.30.30.9-0.80.70.7-0.7-0.7-0.7-0.7-0.4-0.70.50.5-0.71.00.2-0.30.20.4-0.3-0.3-0.2-0.00.30.5-0.50.6
Total sessions with >9 infusions0.00.00.10.3-0.2-0.00.00.20.20.20.00.3-0.00.10.3-0.40.00.30.0-0.10.00.10.20.3-0.2-0.30.3-0.3
Short access day 1 total inactive lever presses1.11.33.7-0.00.50.4-0.4-0.4-0.3-0.5-0.90.00.60.4-0.0-0.61.3-1.3-1.60.51.71.91.80.8-1.7-1.71.7-1.8
Short access day 10 total inactive lever presses0.00.00.1-0.10.2-0.20.2-0.20.0-0.2-0.1-0.10.0-0.1-0.00.10.2-0.2-0.10.10.10.40.20.2-0.1-0.10.1-0.2
Short access day 1 total infusions0.70.82.30.40.0-0.00.00.10.1-0.0-0.50.30.30.20.2-0.80.9-0.8-1.10.31.31.41.50.5-1.4-1.51.5-1.5
Short access day 10 total infusions0.60.72.11.1-0.8-0.70.70.70.70.70.10.9-0.1-0.10.8-1.40.20.4-0.5-0.20.71.01.1-0.3-1.1-1.31.4-1.5
Short access total infusions1.21.33.91.5-1.1-1.01.01.11.11.00.31.5-0.5-0.51.3-2.00.20.3-0.6-0.60.91.21.4-0.3-1.4-1.61.7-1.8
Short access day 1 locomotion1.82.04.4-1.81.91.7-1.7-1.8-1.7-1.9-1.6-1.61.51.4-1.51.51.6-2.1-0.91.20.70.91.00.9-0.7-0.50.4-0.3
Short access day 10 total locomotion0.80.82.4-1.31.01.1-1.1-1.0-1.1-1.0-0.7-1.61.01.0-1.51.40.5-0.30.11.4-0.4-0.2-0.20.30.30.5-0.60.4
Short access total locomotion0.20.20.4-0.30.40.5-0.5-0.3-0.4-0.4-0.5-0.20.50.5-0.20.10.6-0.5-0.40.40.30.50.60.1-0.5-0.50.5-0.5
One hour access (0.3 mA shock)0.70.82.40.8-0.6-0.40.40.40.40.5-0.30.80.10.10.6-1.20.6-0.1-0.9-0.21.21.21.40.2-1.4-1.51.6-1.5
Compulsive drug intake3.94.06.1-2.42.42.3-2.3-2.5-2.3-2.4-2.4-2.22.42.4-2.22.02.2-2.2-1.71.81.51.41.52.1-1.0-0.70.6-0.5
One hour access (shock baseline)2.22.66.72.4-2.1-2.02.02.01.92.01.32.4-1.6-1.52.3-2.6-0.91.20.2-1.60.20.30.4-1.1-0.7-1.01.2-1.1
Social response proportion3.43.77.22.1-2.4-2.32.32.32.22.42.31.9-2.1-2.01.7-1.6-2.22.71.8-1.7-1.6-1.8-1.2-2.01.31.0-0.90.8
Social responses0.10.10.20.2-0.4-0.20.20.40.30.40.40.3-0.4-0.40.2-0.2-0.20.40.1-0.2-0.1-0.3-0.0-0.30.00.0-0.0-0.1
Social time7.29.513.43.2-3.4-3.33.33.33.43.53.43.3-3.4-3.13.5-2.3-3.53.63.5-3.7-3.1-2.8-2.1-2.92.31.8-1.71.9
Soleus weight1.33.810.7-2.71.91.8-1.8-2.0-1.8-1.8-0.7-3.31.10.6-3.03.30.1-0.71.02.5-1.7-1.6-1.1-0.71.92.4-2.52.1
Bone: stiffness0.30.51.0-0.60.80.7-0.7-0.7-0.7-0.8-0.8-0.30.70.7-0.30.30.8-1.0-0.60.20.70.80.41.0-0.7-0.70.6-0.5
Tibialis anterior weight6.321.631.1-5.25.65.6-5.6-5.6-5.6-5.6-5.5-5.15.55.4-5.14.25.1-5.2-4.04.93.43.43.54.3-2.8-2.11.8-1.8
Time to tail flick, vehicle, before self-admin0.80.82.80.3-0.4-0.40.40.40.50.50.80.4-0.7-0.70.60.2-1.10.61.3-0.9-1.3-1.3-1.7-0.91.21.2-1.21.4
Time to tail flick, vehicle, after self-admin1.41.54.41.8-1.7-1.71.71.71.81.81.21.4-1.0-1.01.2-1.8-1.12.10.4-0.5-0.2-0.4-0.6-0.90.1-0.10.2-0.5
Time to tail flick, test, before self-admin1.01.02.6-1.00.70.6-0.6-0.6-0.6-0.60.1-1.30.30.2-1.21.4-0.50.41.10.9-1.5-1.3-1.3-0.21.41.6-1.61.3
Time to tail flick, test, after self-admin0.60.61.7-0.70.40.3-0.3-0.4-0.3-0.30.2-0.8-0.1-0.2-0.71.0-0.50.31.00.4-1.3-1.1-1.1-0.61.11.3-1.31.1
Delta time to tail flick, vehicle, before/after SA2.22.25.32.2-2.0-2.02.02.02.02.01.42.0-1.4-1.31.8-2.3-1.12.00.3-1.2-0.00.00.1-0.7-0.3-0.60.7-0.9
Delta time to tail flick, test, before/after SA0.10.10.30.4-0.4-0.30.30.40.30.40.30.5-0.5-0.60.4-0.4-0.1-0.10.1-0.40.0-0.00.0-0.4-0.1-0.10.2-0.1
Tibia length0.71.96.02.0-1.5-1.51.51.51.51.30.62.0-0.8-0.61.7-2.5-0.10.6-0.9-0.91.31.21.10.2-1.4-1.71.8-1.8
Ambulatory time before self-admin0.10.20.4-0.30.40.5-0.5-0.3-0.4-0.4-0.4-0.10.20.1-0.20.10.5-0.6-0.10.20.10.60.40.6-0.5-0.40.4-0.5
Ambulatory time after self-admin1.31.42.6-1.21.41.3-1.3-1.3-1.3-1.4-1.3-1.11.21.0-1.10.91.4-1.6-1.01.10.91.21.11.4-1.0-0.80.7-0.8
Bone: tissue strength2.12.03.60.7-1.0-1.01.01.01.01.11.41.0-1.4-1.21.2-0.0-1.71.51.9-1.8-1.8-1.8-1.7-1.71.71.6-1.61.8
Total heroin consumption0.50.62.3-0.90.80.8-0.8-0.9-0.9-0.7-0.7-1.30.80.6-1.40.80.7-0.6-0.41.50.10.30.40.5-0.2-0.00.0-0.3
Bone: trabecular number0.10.10.6-0.40.00.1-0.1-0.1-0.1-0.10.2-0.6-0.1-0.4-0.70.4-0.1-0.2-0.10.8-0.2-0.3-0.4-0.20.40.5-0.50.3
Bone: trabecular spacing0.10.20.60.6-0.4-0.40.40.40.40.40.10.6-0.10.10.5-0.8-0.00.3-0.4-0.30.50.40.4-0.1-0.5-0.60.6-0.6
Bone: trabecular thickness0.50.52.0-0.1-0.2-0.20.20.20.20.30.7-0.1-0.7-0.9-0.00.5-0.80.30.9-0.3-1.1-1.0-1.4-0.51.11.2-1.21.1
Bone: trabecular tissue density3.04.28.41.7-2.0-2.02.01.92.02.02.32.2-2.4-2.32.4-1.0-2.41.92.4-2.9-2.0-2.1-1.9-2.01.81.6-1.51.8
Water consumed over 24 hours0.91.12.3-1.51.41.4-1.4-1.3-1.4-1.4-1.0-1.31.11.1-1.31.50.9-1.1-0.70.90.40.20.10.70.00.3-0.30.3
Number of responses in last shaping day0.80.82.4-0.70.81.0-1.0-0.9-0.9-0.8-1.0-0.50.80.7-0.50.41.2-1.5-1.10.61.11.11.10.9-1.0-0.90.9-0.7