Hub : Genes

Tsga10ip

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb gene expression Tsga10ip 0.35 0.16 1.5e-05 0.21 0.08 0.02 0.06 1.1e-05 7.3e-03 9.6e-02 1.3e-02
2 PL gene expression Tsga10ip 0.2 0.1 0.0e+00 0.19 0.18 0.18 0.19 1.4e-20 7.5e-20 3.3e-19 2.3e-20
3 IL gene expression Tsga10ip 0.17 0.11 2.2e-03 0.04 0.06 0.07 0.06 3.7e-02 1.3e-02 1.1e-02 1.9e-02
4 Adipose alternative TSS NM_001270737.1 0.05 0.03 4.6e-04 0.01 0.01 0.01 0.01 1.7e-02 1.1e-02 4.5e-02 4.5e-02
5 Eye gene expression Tsga10ip 0.3 0.15 3.1e-03 0.13 0.07 0.07 0.07 4.7e-03 3.4e-02 2.8e-02 3.3e-02
6 NAcc gene expression Tsga10ip 0.31 0.12 0.0e+00 0.34 0.34 0.33 0.34 3.1e-40 2.3e-40 8.4e-40 1.8e-40
7 Brain gene expression Tsga10ip 0.48 0.14 0.0e+00 0.46 0.44 0.45 0.45 1.6e-47 2.3e-44 2.4e-46 2.3e-46
8 BLA gene expression Tsga10ip 0.36 0.12 0.0e+00 0.31 0.38 0.36 0.38 2.6e-17 3.4e-21 5.6e-20 2.1e-21
9 Adipose gene expression Tsga10ip 0.64 0.13 0.0e+00 0.34 0.32 0.32 0.33 5.6e-39 1.4e-36 2.8e-36 5.6e-38
10 Brain alternative TSS NM_001270737.1 0.08 0.04 2.4e-08 0.09 0.08 0.08 0.08 2.2e-08 1.2e-07 6.4e-08 5.4e-08
11 OFC gene expression Tsga10ip 0.46 0.14 7.3e-11 0.38 0.36 0.36 0.36 5.6e-10 1.5e-09 1.7e-09 1.4e-09
12 PL alternative TSS NM_001270737.1 0.05 0.03 4.9e-06 0.05 0.05 0.05 0.05 1.9e-06 2.8e-06 8.5e-06 4.3e-06
13 pVTA gene expression Tsga10ip 0.17 0.1 6.9e-05 0.09 0.07 0.07 0.06 1.4e-04 8.1e-04 6.8e-04 1.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density0.40.61.90.60.60.51.40.5-0.80.8-0.70.8-0.80.8-0.80.4
Area under the delay curve0.10.10.2-0.1-0.1-0.20.0-0.20.4-0.50.3-0.30.3-0.30.4-0.1
BMI with tail2.78.619.62.92.92.84.42.8-3.03.0-2.92.5-2.52.8-2.62.7
BMI without tail1.22.45.01.61.71.62.21.7-1.41.5-1.51.2-1.21.3-1.41.5
Body weight4.217.720.74.24.24.24.64.2-4.34.3-4.24.1-4.14.1-4.23.9
Weight adjusted by age2.83.24.91.71.71.71.61.5-1.81.8-1.71.9-1.91.8-1.62.2
Bone surface4.37.510.42.82.82.73.22.7-2.82.8-2.82.8-2.82.8-2.81.7
Bone volume1.42.45.01.51.51.42.21.4-1.61.6-1.51.6-1.61.6-1.60.7
Breakpoint value in progressive ratio session3.74.05.31.81.91.92.21.9-2.32.3-2.12.0-2.02.1-2.11.5
Number of licking bursts0.30.40.60.50.50.60.70.6-0.60.6-0.60.7-0.70.7-0.70.5
Context. condit. distance diff. score2.32.83.3-1.7-1.7-1.7-1.5-1.41.8-1.81.7-1.71.7-1.71.7-1.4
Locomotion velocity, session 10.00.00.20.10.10.2-0.30.2-0.10.0-0.10.0-0.00.1-0.00.4
Locomotion distance, session 10.60.71.30.80.80.71.10.7-0.80.8-0.80.8-0.80.9-0.80.9
Locomotion velocity, session 23.44.04.82.01.91.92.22.2-2.02.0-2.02.0-2.02.0-1.91.9
Locomotion distance, session 20.91.31.91.01.01.01.31.0-1.11.1-1.11.1-1.11.1-1.11.4
Locomotion velocity, session 30.10.10.2-0.4-0.4-0.40.2-0.50.3-0.30.3-0.30.3-0.20.3-0.0
Locomotion distance, session 30.00.00.0-0.2-0.2-0.2-0.1-0.10.1-0.10.1-0.10.1-0.10.1-0.1
Stereotopy head waving bouts, day 30.70.81.2-0.8-0.8-0.8-0.6-0.91.1-1.00.9-1.01.0-1.10.9-0.5
Stereotopy head waving duration, day 31.01.21.7-0.9-0.9-0.9-0.9-1.01.3-1.21.1-1.21.2-1.31.1-1.0
Locomotion velocity, session 70.30.30.6-0.7-0.8-0.80.3-0.70.5-0.50.6-0.50.5-0.40.5-0.4
Locomotion distance, session 70.00.10.2-0.3-0.3-0.30.2-0.40.1-0.10.1-0.10.1-0.00.00.4
Stereotopy head waving bouts, day 70.20.31.0-0.4-0.3-0.40.1-0.50.5-0.50.5-0.50.5-0.50.4-1.0
Stereotopy head waving duration, day 70.91.12.21.11.11.11.51.0-0.90.9-1.01.0-1.00.9-1.10.3
Locomotion velocity, session 81.11.32.01.11.11.10.61.2-1.11.1-1.21.1-1.11.2-1.11.4
Locomotion distance, session 80.20.20.3-0.5-0.5-0.5-0.0-0.30.6-0.50.5-0.50.5-0.50.6-0.4
Degree of sensitization distance0.00.00.1-0.1-0.1-0.20.3-0.20.0-0.00.0-0.00.00.0-0.00.3
Degree of sensitization stereotypy0.40.51.30.70.70.71.10.6-0.70.7-0.60.7-0.70.7-0.7-0.1
Conditioned locomotion1.92.22.51.51.51.51.21.4-1.51.4-1.51.6-1.61.5-1.51.5
Cocaine response after cond. corrected1.61.82.1-1.4-1.4-1.4-1.5-1.41.4-1.41.3-1.31.3-1.41.2-0.7
Cocaine response after cond. not corrected1.21.31.7-1.2-1.2-1.2-1.3-1.21.2-1.21.2-1.11.1-1.21.0-0.6
Cocaine response before conditioning0.70.91.10.90.90.91.01.1-1.01.0-0.91.0-1.00.9-1.00.4
Saline control response4.45.86.32.52.52.52.12.4-2.52.5-2.52.3-2.32.5-2.32.4
Bone: connectivity density2.33.65.61.81.81.72.41.8-1.92.0-1.91.9-1.92.0-1.91.4
Bone: cortical apparent density0.20.30.50.60.60.60.50.7-0.50.5-0.60.6-0.60.6-0.60.7
Bone: cortical area0.91.31.61.01.01.11.21.0-1.31.3-1.11.3-1.31.3-1.20.8
Bone: cortical porosity0.10.10.30.30.30.20.60.4-0.20.3-0.20.2-0.20.2-0.30.3
Bone: cortical porosity0.60.60.90.80.80.80.91.0-0.80.8-0.70.7-0.70.6-0.70.8
Bone: cortical thickness3.55.76.82.22.22.31.82.2-2.62.5-2.42.6-2.62.5-2.62.5
Bone: cortical thickness0.91.02.20.80.80.90.30.7-1.11.0-1.01.2-1.21.0-1.11.5
Bone: cortical tissue density0.30.40.60.70.70.70.50.8-0.60.6-0.70.6-0.60.6-0.60.8
Condit. Reinf. active minus inactive responses0.30.30.50.40.40.40.70.4-0.50.5-0.50.7-0.70.5-0.70.4
Condit. Reinf. active-inactive response ratio0.10.10.20.10.20.20.20.1-0.10.1-0.20.4-0.40.2-0.40.0
Condit. Reinf. active responses0.10.20.50.10.10.10.70.1-0.40.4-0.30.5-0.50.4-0.60.2
Condit. Reinf. inactive responses0.00.00.2-0.3-0.3-0.30.4-0.3-0.00.10.1-0.10.1-0.0-0.0-0.2
Incentive salience index mean0.40.51.10.50.60.51.10.6-0.60.7-0.70.9-0.90.7-0.90.6
Condit. Reinf. lever presses0.40.61.10.60.60.61.10.7-0.70.7-0.70.8-0.80.7-0.90.4
Condit. Reinf. active minus inactive responses0.10.20.9-0.3-0.3-0.4-0.0-0.50.3-0.30.3-0.30.3-0.30.3-1.0
Condit. Reinf. active-inactive response ratio0.70.72.4-0.8-0.8-0.8-0.2-1.00.8-0.80.8-0.80.8-0.70.8-1.5
Condit. Reinf. active responses0.00.10.30.20.20.20.5-0.0-0.20.2-0.20.3-0.30.2-0.2-0.3
Condit. Reinf. inactive responses0.30.40.70.70.70.60.60.6-0.60.6-0.60.7-0.70.6-0.70.8
Condit. Reinf. lever presses2.73.74.41.81.81.82.11.8-2.02.0-1.92.0-2.02.1-2.11.2
Condit. Reinf. lever reinforcers received0.20.30.60.60.60.60.80.4-0.60.6-0.60.6-0.60.6-0.60.0
Conditioned reinforcement - actives0.30.30.8-0.6-0.6-0.5-0.5-0.50.3-0.30.4-0.50.5-0.30.5-0.9
Conditioned reinforcement - inactives6.87.68.9-2.9-2.9-2.9-2.6-2.92.7-2.72.7-2.72.7-2.62.5-3.0
Conditioned locomotion9.211.112.0-3.4-3.4-3.3-3.5-3.33.2-3.23.3-3.43.4-3.23.3-3.2
Patch foraging indifference point 0 sec0.10.10.3-0.3-0.3-0.3-0.1-0.20.2-0.20.3-0.30.3-0.20.4-0.5
Patch foraging indifference point AUC4.14.75.62.32.32.22.12.3-2.42.4-2.21.9-1.92.2-2.21.8
Delay disc. indifference point, 0s delay0.60.71.4-0.5-0.5-0.5-0.5-0.51.1-1.10.8-1.21.2-1.01.00.0
Delay disc. indifference point, 16s delay0.90.91.6-1.0-1.0-1.1-0.4-1.11.0-1.01.0-0.60.6-0.90.9-1.3
Delay disc. indifference point, 2s delay0.10.10.4-0.3-0.3-0.3-0.2-0.30.2-0.30.4-0.50.5-0.40.4-0.6
Delay disc. indifference point, 24s delay0.10.10.3-0.3-0.3-0.2-0.5-0.30.4-0.40.30.0-0.0-0.30.20.2
Delay disc. indifference point, 4s delay0.20.20.3-0.3-0.3-0.4-0.4-0.40.5-0.50.4-0.50.5-0.50.5-0.1
Delay disc. indifference point, 8s delay0.10.10.30.00.0-0.0-0.2-0.10.5-0.50.2-0.30.3-0.30.20.3
Indifference point function ln k9.513.315.1-3.8-3.8-3.7-3.6-3.93.6-3.63.8-3.63.6-3.83.6-2.8
Indifference point function log k9.513.315.1-3.8-3.8-3.7-3.6-3.93.6-3.63.8-3.63.6-3.83.6-2.8
Patch foraging total patch changes 0 sec0.00.00.1-0.2-0.2-0.2-0.3-0.10.1-0.10.2-0.20.2-0.20.3-0.2
Patch foraging total patch changes 12 sec5.57.18.42.62.62.62.82.8-2.82.9-2.82.4-2.42.9-2.52.3
Patch foraging total patch changes 18 sec0.60.81.30.90.90.91.11.1-0.90.9-0.90.8-0.80.9-0.90.5
Patch foraging total patch changes 24 sec2.83.44.61.91.91.91.42.1-1.81.9-2.01.7-1.72.0-1.71.8
Patch foraging total patch changes 6 sec1.21.82.41.11.21.11.41.3-1.41.4-1.41.3-1.31.6-1.41.3
Patch foraging time to switch 0 sec2.13.26.91.61.61.62.61.6-1.51.5-1.72.1-2.11.7-1.91.3
Patch foraging water rate 0 sec4.67.411.3-2.6-2.6-2.6-3.4-2.62.5-2.62.7-2.92.9-2.72.8-2.5
Patch foraging water rate 12 sec9.514.623.4-3.7-3.7-3.6-4.8-3.83.8-3.83.8-3.83.8-3.93.9-2.7
Patch foraging water rate 18 sec3.54.77.1-2.2-2.2-2.2-2.7-2.22.2-2.22.1-2.02.0-2.02.3-1.5
Patch foraging water rate 24 sec4.86.710.3-2.3-2.4-2.4-3.2-2.42.8-2.82.6-2.62.6-2.62.7-2.1
Patch foraging water rate 6 sec4.16.010.5-2.5-2.5-2.5-3.2-2.52.5-2.52.4-2.32.3-2.42.3-1.5
Seeking ratio, delayed vs. immediate footshock0.10.10.3-0.3-0.3-0.30.3-0.20.2-0.20.10.0-0.0-0.1-0.10.6
Distance traveled before self-admin0.50.51.01.00.90.80.90.9-0.70.7-0.70.5-0.50.6-0.50.2
Distance traveled after self-admin0.20.20.50.70.50.50.60.5-0.50.5-0.50.2-0.20.4-0.20.1
Extensor digitorum longus weight8.934.936.15.95.95.95.95.8-5.95.9-5.96.0-6.06.0-6.05.5
Bone: elastic displacement1.01.13.2-1.1-1.1-1.0-1.8-1.30.9-0.91.0-0.80.8-1.00.8-0.3
Bone: elastic work0.81.12.10.90.91.00.30.8-1.21.2-1.01.1-1.11.1-1.11.5
Bone: endosteal estimation0.92.02.6-1.3-1.3-1.4-0.5-1.41.4-1.41.5-1.51.5-1.41.6-1.6
Bone: endosteal perimeter1.22.44.7-1.5-1.5-1.6-0.6-1.61.5-1.51.6-1.61.6-1.51.7-2.2
Epididymis fat weight3.17.28.5-2.5-2.5-2.6-2.2-2.52.7-2.72.8-2.92.9-2.82.8-2.9
Delta time in closed arm before/after self-admin0.10.11.0-0.10.00.1-0.20.0-0.10.1-0.20.1-0.10.2-0.21.0
Delta time in open arm before/after self-admin0.10.10.70.60.20.20.30.2-0.20.2-0.20.1-0.10.2-0.1-0.8
Diff in mean of infusions in LGA sessions0.40.50.80.90.60.60.50.6-0.80.8-0.70.8-0.80.8-0.80.3
Delay discount exponential model param0.00.00.10.10.10.1-0.00.1-0.30.3-0.20.2-0.20.3-0.3-0.0
Extinction: sum of active levers before priming5.25.27.72.32.22.22.82.2-2.42.5-2.32.1-2.12.3-2.11.9
Active lever presses in extinction session 62.62.53.01.71.71.71.31.7-1.71.7-1.71.4-1.41.7-1.51.2
Bone: final force3.25.25.82.42.42.32.42.4-2.22.2-2.32.3-2.32.3-2.21.8
Bone: final moment2.84.54.92.22.22.22.22.2-2.12.1-2.22.1-2.12.2-2.11.7
Food consumed during 24 hour testing period0.00.10.10.20.20.3-0.10.3-0.20.2-0.20.4-0.40.2-0.3-0.2
Glucose2.13.13.7-1.7-1.8-1.9-1.1-1.81.9-1.91.9-1.71.7-1.91.8-1.7
Heart weight3.75.26.1-2.4-2.5-2.4-2.1-2.32.4-2.42.4-2.02.0-2.42.1-2.1
Delay discount hyperbolic model param0.00.00.10.00.00.1-0.00.1-0.30.3-0.20.2-0.20.2-0.3-0.0
Intermittent access intake day 1-15 change0.60.61.0-1.0-1.0-0.8-1.0-0.80.8-0.80.8-0.50.5-0.60.5-1.0
Intermittent access intake escalation0.60.61.0-1.0-0.9-0.8-0.8-0.80.8-0.80.7-0.60.6-0.60.5-0.8
Intermittent access intake escalation 20.20.20.5-0.5-0.5-0.4-0.6-0.40.4-0.40.4-0.50.5-0.40.3-0.7
Intermitt. access day 1 inactive lever presses2.52.74.5-1.7-1.6-1.8-1.4-1.81.7-1.71.7-1.41.4-1.71.3-2.1
Intermitt. access day 15 inactive lever presses2.42.63.7-1.8-1.8-1.9-1.3-1.91.6-1.61.5-1.41.4-1.31.2-1.9
Intermitt. access escalation Index3.83.44.9-1.7-1.7-1.8-1.5-1.81.8-1.81.8-2.12.1-1.82.2-1.5
Intermittent access day 1 total infusions5.36.27.4-2.7-2.7-2.7-1.6-2.62.5-2.52.5-2.62.6-2.42.3-2.5
Intermittent access day 15 total infusions8.39.311.7-3.4-3.4-3.3-2.6-3.33.0-3.03.1-2.82.8-2.82.7-3.2
Intermittent access terminal intake (last 3 days)5.76.28.7-2.8-2.8-2.7-1.9-2.72.5-2.52.5-2.32.3-2.32.2-3.0
Intermittent access total infusions4.34.86.5-2.5-2.5-2.5-1.5-2.42.2-2.12.2-2.02.0-1.91.9-2.4
Intermittent access day 1 locomotion3.33.54.8-2.1-2.1-2.2-1.1-2.11.9-1.91.9-1.81.8-1.81.5-1.7
Intermittent access day 15 total locomotion5.05.46.9-2.6-2.6-2.6-1.8-2.52.3-2.32.3-2.12.1-2.12.1-2.4
Intermittent access total locomotion6.06.98.5-2.8-2.8-2.9-1.7-2.82.7-2.72.6-2.72.7-2.52.3-2.6
Intermittent access standard deviation1.21.21.6-1.2-1.2-1.2-1.3-1.21.2-1.21.1-1.01.0-1.00.9-1.0
Left kidney weight0.71.93.1-1.4-1.4-1.3-1.0-1.31.4-1.51.4-1.31.3-1.51.3-1.8
Right kidney weight0.10.42.2-0.5-0.6-0.5-0.4-0.30.6-0.60.6-0.50.5-0.50.4-1.5
Cocaine induced anxiety0.00.00.00.00.00.0-0.00.0-0.10.00.10.0-0.0-0.1-0.2-0.0
Post-drug Anxiety1.31.42.41.21.21.31.01.2-1.31.3-1.11.2-1.21.1-1.50.9
Baseline Anxiety2.52.73.41.61.61.71.41.6-1.71.7-1.81.5-1.51.8-1.71.3
Tail length0.72.02.71.51.51.60.31.5-1.41.3-1.41.5-1.51.3-1.41.6
Length with tail2.59.110.63.03.03.02.23.0-3.13.0-3.03.2-3.23.0-3.32.9
Length without tail2.96.47.82.42.42.42.22.3-2.82.7-2.62.6-2.62.7-2.62.4
Times rat made contact with spout0.50.61.00.70.70.70.70.7-0.70.7-0.80.9-0.90.7-0.81.0
Lifetime Intake3.74.25.6-2.4-2.4-2.4-1.3-2.32.0-2.02.0-1.91.9-1.81.7-2.1
Liver weight, left0.10.10.4-0.2-0.2-0.2-0.3-0.30.3-0.30.4-0.60.6-0.40.6-0.1
Liver weight, right0.10.10.3-0.3-0.3-0.3-0.5-0.40.3-0.30.3-0.40.4-0.30.40.2
Locomotor activity1.82.95.6-1.8-1.8-1.7-2.4-1.71.7-1.71.7-1.51.5-1.61.6-0.9
Locomotor testing distance2.44.08.7-2.1-2.1-2.0-2.9-2.12.0-2.02.0-1.81.8-2.01.9-0.9
Locomotor testing rearing2.43.66.8-1.9-1.9-2.0-2.6-2.01.9-1.91.9-1.71.7-1.91.9-1.2
Locomotion in novel chamber5.16.36.8-2.5-2.6-2.6-2.3-2.52.6-2.62.5-2.42.4-2.42.6-2.6
Locomotion in novel chamber post-restriction3.54.26.3-2.1-2.1-2.1-1.8-2.01.9-1.92.0-2.02.0-1.92.0-2.5
Fecal boli incidents, locomotor time 10.10.10.20.20.20.20.50.2-0.30.3-0.10.4-0.40.0-0.3-0.5
Change in fecal boli incidents, locomotor task0.10.10.90.00.0-0.0-0.1-0.10.1-0.0-0.0-0.10.10.00.21.0
Time >=10cm from walls, locomotor time 10.60.60.9-0.8-0.8-0.90.1-0.80.9-1.00.9-0.70.7-0.90.6-0.8
Bouts of movement, locomotor time 11.81.92.71.51.51.41.21.4-1.11.1-1.41.6-1.61.3-1.61.0
Total resting periods, locomotor time 11.31.42.11.31.31.21.11.1-1.01.0-1.11.5-1.51.1-1.30.6
Rest time, locomotor task time 11.41.52.4-1.1-1.1-1.2-1.5-1.21.1-1.11.3-1.21.2-1.31.2-1.5
Distance moved, locomotor task time 10.10.10.50.20.20.20.70.2-0.30.3-0.40.2-0.20.5-0.20.7
Vertical activity count, locomotor time 11.31.41.9-1.3-1.3-1.3-1.1-1.41.2-1.11.2-1.11.1-1.11.1-0.7
Time >=10cm from walls, locomotor time 20.00.00.10.30.30.30.40.30.1-0.1-0.10.0-0.00.0-0.0-0.2
Bouts of movement, locomotor time 20.60.71.00.70.70.70.90.7-0.70.9-0.81.0-1.00.8-1.00.8
Total resting periods, locomotor time 20.30.30.50.50.50.40.70.5-0.50.7-0.60.7-0.70.6-0.70.5
Rest time, locomotor task time 22.63.03.6-1.6-1.6-1.7-1.6-1.61.8-1.91.8-1.71.7-1.91.8-1.6
Distance moved, locomotor task time 21.31.52.01.21.21.21.11.2-1.21.2-1.31.0-1.01.4-1.11.4
Vertical activity count, locomotor time 20.10.10.5-0.2-0.2-0.1-0.7-0.2-0.0-0.0-0.00.0-0.00.1-0.10.7
Light reinforcement 10.20.30.7-0.5-0.5-0.4-0.8-0.30.4-0.30.5-0.70.7-0.60.7-0.3
Light reinforcement 20.91.22.8-1.0-1.0-1.0-0.9-1.01.0-0.91.2-1.01.0-1.21.0-1.7
Bone: marrow area1.02.12.7-1.4-1.4-1.4-0.6-1.41.5-1.51.5-1.61.6-1.51.6-1.6
Bone: maximum diameter0.10.30.30.60.60.50.60.5-0.50.5-0.50.5-0.50.5-0.4-0.3
Bone: maximum force3.76.49.82.52.52.43.12.5-2.52.5-2.52.6-2.62.6-2.51.7
Bone: maximum moment3.25.58.42.32.32.22.92.3-2.32.3-2.42.4-2.42.4-2.31.6
Mean time between licks in bursts0.40.61.90.70.70.80.20.8-0.70.7-0.90.6-0.60.8-0.71.4
Mean num. licks in bursts0.20.20.4-0.4-0.4-0.4-0.6-0.50.5-0.50.5-0.40.4-0.50.4-0.2
Cd content in liver1.61.72.4-1.2-1.2-1.2-1.4-1.11.3-1.31.3-1.41.4-1.21.4-1.5
Co content in liver1.51.84.2-1.3-1.3-1.2-2.0-1.11.4-1.41.4-1.31.3-1.41.4-0.4
Cu content in liver0.40.50.90.60.60.50.90.5-0.70.7-0.60.8-0.80.7-0.70.6
Fe content in liver0.10.10.30.40.40.40.30.3-0.50.5-0.40.4-0.40.4-0.30.2
K content in liver2.22.13.51.31.31.31.91.3-1.41.4-1.41.7-1.71.5-1.71.2
Mg content in liver0.20.21.20.30.30.21.10.2-0.30.3-0.30.5-0.50.4-0.50.2
Mn content in liver3.13.64.51.81.81.81.91.8-2.02.0-1.92.1-2.11.9-2.11.0
Na content in liver1.21.31.51.21.21.21.01.2-1.21.2-1.11.2-1.21.1-1.20.7
Rb content in liver1.72.12.7-1.5-1.5-1.5-1.0-1.61.4-1.31.4-1.71.7-1.31.6-1.1
Se content in liver0.10.10.5-0.0-0.0-0.10.4-0.1-0.10.1-0.10.3-0.30.2-0.2-0.7
Sr content in liver3.22.93.91.91.92.01.21.9-1.71.7-1.81.5-1.51.7-1.71.3
Zn content in liver1.51.72.31.21.21.21.51.2-1.21.2-1.21.5-1.51.2-1.41.1
Bone: minimum diameter0.71.32.0-1.2-1.2-1.3-0.1-1.31.1-1.11.2-1.21.2-1.11.2-1.4
Time in familiar zone, hab. session 10.20.20.5-0.6-0.6-0.6-0.1-0.70.3-0.30.4-0.40.4-0.40.4-0.5
Time in novel zone, hab. session 10.30.21.0-0.3-0.3-0.3-1.0-0.20.6-0.60.4-0.50.5-0.50.50.1
Total zone transitions, hab. session 10.91.31.71.01.01.01.30.9-1.21.2-1.11.2-1.21.2-1.21.1
Total locomotion distance, hab. session 10.30.40.5-0.6-0.6-0.6-0.1-0.70.7-0.70.7-0.70.7-0.70.7-0.6
Locomotion velocity, hab. session 10.00.00.1-0.1-0.1-0.10.3-0.20.2-0.20.2-0.20.2-0.20.2-0.1
Time in familiar zone, hab. session 20.10.10.4-0.2-0.2-0.1-0.7-0.2-0.0-0.00.0-0.00.0-0.0-0.00.6
Time in novel zone, hab. session 20.10.10.50.40.30.30.70.3-0.10.2-0.20.1-0.10.2-0.1-0.2
Total zone transitions, hab. session 21.41.93.61.41.41.31.91.4-1.31.3-1.31.2-1.21.3-1.21.2
Total locomotion distance, hab. session 20.00.00.30.0-0.0-0.10.5-0.00.2-0.20.1-0.20.2-0.20.20.0
Locomotion velocity, hab. session 20.10.10.2-0.2-0.2-0.30.5-0.20.4-0.40.3-0.40.4-0.40.4-0.3
Novel to familiar place preference ratio1.11.12.21.21.21.11.51.0-1.11.1-1.11.0-1.01.0-1.00.2
Novelty place preference0.50.51.20.80.80.71.10.6-0.70.7-0.60.5-0.50.6-0.5-0.2
Time in novel zone, NPP test0.30.30.80.70.60.60.90.5-0.60.6-0.50.4-0.40.5-0.4-0.2
Total zone transitions, NPP test2.53.54.72.02.01.92.22.0-1.81.9-1.91.8-1.81.8-1.81.5
Total locomotion distance, NPP test0.10.10.50.30.30.20.70.3-0.10.1-0.20.1-0.10.1-0.10.3
Locomotion velocity, NPP test0.10.10.70.40.30.30.80.3-0.20.3-0.30.3-0.30.2-0.20.3
Intraocular pressure1.01.33.1-1.0-1.0-1.0-1.3-1.01.2-1.21.2-1.01.0-1.21.0-1.7
Delta distance traveled before/after self-admin0.00.00.1-0.1-0.2-0.2-0.3-0.20.1-0.10.1-0.30.3-0.00.20.1
Delta ambulatory time before/after self-admin0.00.00.1-0.1-0.1-0.1-0.3-0.1-0.00.00.0-0.20.20.00.20.3
Parametrial fat weight2.75.26.6-2.2-2.2-2.2-1.3-2.22.4-2.32.4-2.42.4-2.62.5-2.6
Pavlov. Cond. lever latency0.20.30.6-0.6-0.6-0.6-0.8-0.70.6-0.60.5-0.40.4-0.50.5-0.2
Pavlov. Cond. magazine entry latency0.10.21.00.50.50.51.00.4-0.30.3-0.30.2-0.20.3-0.3-0.2
Pavlov. Cond. change in total contacts0.10.10.70.20.20.20.80.2-0.20.2-0.10.2-0.20.1-0.3-0.7
Pavlov. Cond. index score0.10.10.40.40.50.50.60.4-0.30.3-0.30.3-0.30.2-0.4-0.2
Pavlov. Cond. latency score0.10.10.20.30.30.30.50.3-0.20.2-0.20.1-0.10.1-0.2-0.2
Pavlov. Cond. lever contacts0.00.00.10.10.10.10.30.1-0.10.1-0.00.0-0.0-0.0-0.2-0.1
Pavlov. Cond. magazine entry number0.20.30.5-0.6-0.7-0.6-0.7-0.50.5-0.50.5-0.50.5-0.50.50.2
Pavlov. Cond. intertrial magazine entries0.40.40.9-0.9-1.0-0.9-0.7-0.80.4-0.40.6-0.50.5-0.40.5-0.7
Pavlov. Cond. lever-magazine prob. diff.0.30.40.80.70.80.70.90.6-0.60.6-0.50.5-0.50.5-0.6-0.0
Pavlov. Cond. response bias0.10.10.20.30.40.40.50.3-0.30.3-0.30.3-0.30.3-0.4-0.2
Pavlov. Cond. lever latency0.60.81.2-0.9-0.9-0.9-1.1-0.90.9-0.90.9-0.90.9-0.91.0-0.3
Pavlov. Cond. magazine entry latency4.45.16.32.12.12.12.52.0-2.32.3-2.32.3-2.32.4-2.42.0
Pavlov. Cond. change in total contacts2.33.15.41.71.71.72.31.6-1.91.9-1.71.8-1.81.8-1.80.7
Pavlov. Cond. index score3.03.95.51.91.91.92.31.8-2.02.0-2.02.0-2.02.1-2.11.3
Pavlov. Cond. latency score2.53.14.71.71.71.62.21.6-1.81.8-1.81.9-1.91.9-1.91.1
Pavlov. Cond. lever contacts0.60.81.00.90.90.90.80.9-1.00.9-0.90.9-0.90.9-1.00.4
Pavlov. Cond. magazine entry number7.79.411.1-3.0-3.0-3.0-3.3-2.83.1-3.13.1-3.13.1-3.23.2-2.5
Pavlov. Cond. intertrial magazine entries1.41.82.1-1.3-1.3-1.3-1.4-1.11.4-1.41.4-1.41.4-1.41.4-1.4
Pavlov. Cond. lever-magazine prob. diff.3.64.66.32.12.12.12.52.0-2.22.2-2.22.2-2.22.3-2.31.5
Pavlov. Cond. response bias2.22.93.31.71.71.71.81.7-1.81.8-1.81.8-1.81.8-1.81.1
Time in closed arm before self-admin0.10.10.30.40.20.20.40.2-0.10.2-0.10.3-0.3-0.0-0.1-0.5
Time in closed arm after self-admin0.00.00.1-0.3-0.3-0.20.0-0.3-0.00.00.10.2-0.2-0.1-0.10.3
Time in open arm before self-admin0.60.61.4-1.2-0.8-0.7-1.0-0.80.9-0.90.7-0.60.6-0.70.70.5
Time in open arm after self-admin0.20.20.6-0.5-0.4-0.3-0.8-0.40.5-0.50.4-0.40.4-0.40.5-0.6
Bone: periosteal estimation0.00.10.3-0.1-0.1-0.10.4-0.20.0-0.00.1-0.10.1-0.00.2-0.5
Bone: periosteal perimeter0.10.10.40.30.30.30.70.2-0.40.4-0.30.4-0.40.4-0.3-0.2
Bone: post-yield work0.60.86.20.60.60.42.50.7-0.50.6-0.60.6-0.60.6-0.5-0.6
Progressive ratio test 1 active lever presses3.03.13.8-1.9-2.0-1.9-1.7-1.91.7-1.71.7-1.71.7-1.61.5-1.8
Progressive ratio test 1 breakpoint2.72.83.4-1.8-1.9-1.8-1.6-1.81.6-1.61.6-1.61.6-1.51.3-1.7
Progressive ratio test 1 inactive lever presses1.31.41.7-1.3-1.3-1.3-1.0-1.31.2-1.21.1-1.21.2-1.11.0-0.9
Progressive ratio test 2 active lever presses4.34.76.4-2.5-2.5-2.4-1.8-2.42.1-2.12.1-2.02.0-1.81.8-2.4
Progressive ratio test 2 breakpoint5.66.38.0-2.8-2.8-2.7-2.4-2.72.4-2.42.4-2.32.3-2.22.2-2.7
Progressive ratio test 2 inactive lever presses9.310.712.7-3.6-3.5-3.5-2.8-3.43.3-3.33.3-3.33.3-3.13.0-3.2
Incentive Sensitization - Responses0.40.41.0-0.9-0.9-0.8-0.3-0.80.5-0.50.5-0.50.5-0.30.4-1.0
Incentive Sensitization - Breakpoint0.70.71.4-1.1-1.1-1.0-0.5-1.00.6-0.60.7-0.60.6-0.50.6-1.2
Sum of active levers in priming session hrs 5-61.61.62.31.31.21.31.01.2-1.41.4-1.41.2-1.21.5-1.20.7
Progressive ratio2.22.55.31.71.71.62.31.7-1.51.5-1.51.5-1.51.4-1.31.2
Food seeking constrained by brief footshock0.30.31.40.30.40.40.20.3-0.60.5-0.50.7-0.70.6-0.51.2
Seeking ratio, punishment vs. effort1.82.14.9-1.7-1.6-1.5-2.2-1.61.3-1.41.4-1.31.3-1.31.3-0.5
Retroperitoneal fat weight6.220.221.6-4.6-4.6-4.6-3.7-4.64.4-4.44.6-4.64.6-4.54.6-4.5
Reaction time number correct0.40.50.90.90.90.90.20.8-0.80.7-0.70.6-0.60.6-0.50.6
Reaction time mean minus median3.54.76.62.12.12.02.52.1-2.02.0-2.12.6-2.62.1-2.31.4
Reaction time mean minus median AUC2.12.74.11.61.51.61.61.6-1.51.5-1.62.0-2.01.6-1.81.2
Reaction time num false alarms0.30.40.7-0.8-0.8-0.7-0.8-0.70.3-0.30.5-0.50.5-0.40.50.5
Reaction time num false alarms AUC0.10.11.3-0.1-0.10.0-0.10.0-0.40.4-0.20.2-0.20.3-0.31.1
Reaction time trials correct on left0.40.50.90.90.90.90.20.8-0.80.7-0.70.6-0.60.6-0.50.6
Reaction time trials on left0.50.71.11.01.01.00.30.9-0.90.8-0.80.7-0.70.7-0.60.7
Reaction time mean0.10.10.20.30.30.20.40.3-0.00.0-0.20.4-0.40.2-0.2-0.2
Reaction time mean AUC0.00.10.20.20.20.10.50.20.0-0.0-0.20.4-0.40.1-0.1-0.3
Median of all reaction times0.10.10.2-0.1-0.1-0.20.0-0.20.4-0.40.2-0.10.1-0.30.3-0.5
Reaction time omissions1.82.43.91.51.51.51.61.3-1.51.4-1.42.0-2.01.4-1.61.4
Reaction time false alarm rate0.20.30.7-0.9-0.9-0.7-0.5-0.70.3-0.30.4-0.30.3-0.40.20.5
Reaction time premature initiation rate2.53.35.21.81.81.91.11.9-1.91.9-1.91.7-1.71.8-1.82.3
Reaction time premature initiations4.15.87.72.52.52.61.52.5-2.52.5-2.52.3-2.32.4-2.32.8
Std. dev. reaction times1.01.42.31.21.21.11.31.2-1.00.9-1.11.5-1.51.1-1.20.6
Reaction time trials completed0.50.71.11.01.01.00.30.9-0.90.8-0.80.7-0.70.7-0.60.7
Reaction time trials AUC0.30.40.70.80.80.80.10.6-0.70.6-0.60.4-0.40.5-0.40.6
Run reversals in cocaine runway, females0.60.62.50.60.60.51.10.6-0.60.6-0.70.6-0.60.7-0.61.6
Run reversals in cocaine runway, males0.30.31.2-0.6-0.5-0.4-1.1-0.50.4-0.50.4-0.30.3-0.40.3-0.0
Latency to leave start box in cocaine runway0.10.10.4-0.2-0.3-0.30.5-0.20.00.00.10.1-0.1-0.0-0.0-0.7
Latency to leave start box in cocaine runway, F0.00.00.30.00.0-0.00.50.0-0.10.1-0.10.2-0.20.1-0.0-0.4
Latency to leave start box in cocaine runway, M0.00.00.1-0.1-0.3-0.30.2-0.2-0.10.20.00.1-0.10.1-0.2-0.2
Std. dev. time between licks in bursts0.10.20.7-0.3-0.3-0.2-0.8-0.20.3-0.30.2-0.40.4-0.30.40.6
Total sessions with >9 infusions1.61.72.4-1.5-1.5-1.5-0.9-1.51.3-1.31.4-1.21.2-1.31.1-1.1
Short access day 1 total inactive lever presses4.34.86.3-2.1-2.1-2.3-1.8-2.32.1-2.12.1-2.52.5-2.02.1-2.4
Short access day 10 total inactive lever presses3.84.24.9-2.1-2.1-2.2-2.1-2.22.1-2.12.1-1.91.9-2.01.7-1.9
Short access day 1 total infusions2.93.14.1-1.7-1.8-1.9-1.0-1.81.8-1.81.8-1.71.7-1.71.7-2.0
Short access day 10 total infusions1.11.22.1-1.4-1.4-1.4-0.1-1.40.9-0.91.1-1.11.1-0.90.9-1.0
Short access total infusions1.11.31.8-1.3-1.3-1.3-0.5-1.31.1-1.11.1-1.21.2-1.00.9-1.1
Short access day 1 locomotion2.12.33.5-1.8-1.8-1.9-1.0-1.81.6-1.61.5-1.21.2-1.21.3-1.3
Short access day 10 total locomotion1.31.42.2-1.4-1.3-1.5-0.6-1.51.2-1.21.2-1.21.2-1.11.1-0.7
Short access total locomotion1.11.11.8-1.2-1.2-1.3-0.5-1.31.1-1.11.1-1.01.0-0.90.9-0.8
One hour access (0.3 mA shock)10.612.414.8-3.8-3.8-3.8-3.4-3.73.7-3.73.6-3.23.2-3.43.0-3.5
Compulsive drug intake2.82.84.91.81.81.71.01.7-1.61.6-1.71.7-1.71.6-1.52.2
One hour access (shock baseline)9.410.914.3-3.6-3.6-3.5-2.8-3.53.3-3.33.4-3.03.0-3.12.8-3.8
Social response proportion0.91.01.41.01.01.01.01.1-0.80.9-1.01.2-1.21.0-1.10.6
Social responses0.30.30.60.50.50.50.20.4-0.50.5-0.60.8-0.80.7-0.70.6
Social time0.40.50.80.80.90.80.20.7-0.50.5-0.80.8-0.80.8-0.70.9
Soleus weight4.713.715.1-3.7-3.7-3.6-3.4-3.73.9-3.93.8-3.73.7-3.83.8-3.3
Bone: stiffness2.94.57.82.22.22.12.82.2-2.12.1-2.12.1-2.12.2-2.01.2
Tibialis anterior weight12.442.444.96.66.66.75.86.6-6.76.6-6.66.6-6.66.7-6.65.9
Time to tail flick, vehicle, before self-admin0.50.50.90.60.70.71.00.7-0.80.7-0.60.7-0.70.6-0.70.8
Time to tail flick, vehicle, after self-admin1.31.42.00.81.31.21.31.3-1.01.0-1.21.2-1.21.2-1.21.4
Time to tail flick, test, before self-admin0.50.51.0-0.9-0.8-0.9-0.3-0.81.0-1.00.7-0.50.5-0.60.6-0.2
Time to tail flick, test, after self-admin0.00.00.20.00.20.2-0.10.20.1-0.1-0.00.3-0.30.0-0.30.5
Delta time to tail flick, vehicle, before/after SA0.40.40.70.50.70.60.70.7-0.40.4-0.70.8-0.80.7-0.80.7
Delta time to tail flick, test, before/after SA1.21.11.60.81.21.30.31.2-1.11.1-0.91.1-1.10.8-1.11.0
Tibia length1.13.24.11.91.91.91.81.8-2.02.0-1.81.8-1.81.8-1.70.8
Ambulatory time before self-admin0.40.40.80.70.70.60.90.7-0.60.6-0.60.5-0.50.6-0.5-0.1
Ambulatory time after self-admin0.10.10.50.2-0.3-0.30.3-0.30.2-0.20.2-0.40.4-0.30.4-0.7
Bone: tissue strength0.10.00.20.10.10.10.40.4-0.10.1-0.20.2-0.20.2-0.2-0.2
Total heroin consumption6.17.18.42.82.82.82.82.8-2.92.9-2.82.5-2.52.7-2.51.8
Bone: trabecular number0.50.82.20.70.70.61.50.5-0.90.9-0.81.0-1.01.0-1.00.3
Bone: trabecular spacing0.20.30.6-0.5-0.5-0.5-0.8-0.30.6-0.60.5-0.60.6-0.60.6-0.1
Bone: trabecular thickness0.40.51.1-0.9-0.9-0.9-0.2-1.00.7-0.70.7-0.60.6-0.60.5-0.8
Bone: trabecular tissue density4.15.86.3-2.4-2.4-2.4-2.3-2.32.5-2.52.4-2.42.4-2.42.4-2.4
Water consumed over 24 hours0.91.01.31.11.11.10.61.1-1.01.0-1.01.1-1.11.0-1.11.0
Number of responses in last shaping day1.31.42.1-1.2-1.2-1.2-1.5-1.31.1-1.11.1-1.01.0-1.01.0-1.3