Hub : Genes

Dcun1d1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver alternative polyA NM_001395100.1 0.05 0.03 1.6e-04 0.02 0.02 0.02 0.01 3.1e-03 2.6e-03 5.1e-03 7.6e-03
2 Liver isoform ratio NM_001395100.1 0.03 0.03 3.5e-03 0 0.01 -0 -0 2.4e-01 6.4e-02 4.8e-01 6.2e-01
3 NAcc alternative polyA NM_001395100.1 0.03 0.02 4.6e-05 0.02 0.03 0.02 0.02 1.7e-04 2.8e-05 1.2e-04 1.9e-04
4 NAcc alternative polyA XM_006232261.5 0.03 0.02 4.8e-05 0.01 0.03 0.01 0.02 2.8e-03 4.2e-05 3.4e-03 5.8e-04
5 NAcc alternative polyA NM_001395100.1 0.03 0.02 3.5e-05 0.02 0.03 0.02 0.02 1.4e-03 4.0e-05 1.4e-03 3.0e-04
6 NAcc alternative polyA XM_006232261.5 0.03 0.02 2.6e-05 0.01 0.03 0.01 0.02 2.4e-03 3.8e-05 1.9e-03 3.5e-04
7 PL alternative polyA NM_001395100.1 0.03 0.02 6.6e-03 0.01 0.01 0.01 0.01 1.5e-02 7.5e-03 7.7e-03 1.3e-02
8 NAcc isoform ratio NM_001395100.1 0.02 0.01 6.5e-03 0 0.01 0 0 1.8e-01 7.5e-03 6.5e-02 1.2e-01
9 PL alternative polyA XM_006232261.5 0.03 0.02 8.2e-03 0.01 0.01 0.01 0.01 1.8e-02 9.2e-03 1.5e-02 3.2e-02
10 PL alternative polyA NM_001395100.1 0.04 0.03 1.5e-03 0.01 0.02 0.02 0.01 8.1e-03 3.0e-03 4.6e-03 8.3e-03
11 PL alternative polyA XM_006232261.5 0.04 0.03 1.9e-03 0.01 0.02 0.01 0.01 1.1e-02 3.5e-03 9.4e-03 1.7e-02
12 pVTA alternative polyA XM_006232261.5 0.14 0.16 9.9e-05 0.02 0.03 0.02 0.02 1.2e-02 1.0e-03 1.7e-02 6.5e-03
13 pVTA alternative polyA XM_006232261.5 0.1 0.09 1.5e-04 0.03 0.03 0.01 0.02 1.4e-03 1.6e-03 3.3e-02 7.6e-03
14 pVTA alternative polyA NM_001395100.1 0.1 0.1 1.4e-04 0.03 0.03 0.01 0.02 1.3e-03 1.6e-03 3.9e-02 7.8e-03
15 pVTA alternative polyA NM_001395100.1 0.09 0.08 5.8e-05 0.04 0.03 0.01 0.02 6.8e-04 9.0e-04 2.4e-02 4.4e-03
16 pVTA isoform ratio NM_001395100.1 0.04 0.03 5.1e-03 0.02 0.02 0 0.02 9.5e-03 4.3e-03 1.3e-01 4.8e-03
17 PL isoform ratio NM_001395100.1 0.03 0.02 9.4e-03 0 0.01 0 0 8.8e-02 2.0e-02 8.3e-02 7.7e-02
18 Liver alternative polyA XM_006232261.5 0.03 0.02 8.5e-03 0.01 0 -0 0 5.7e-02 1.1e-01 5.2e-01 2.7e-01
19 Liver alternative polyA XM_006232261.5 0.04 0.03 2.6e-04 0.02 0.02 0.02 0.01 6.2e-03 5.0e-03 4.5e-03 9.8e-03
20 Liver gene expression Dcun1d1 0.16 0.09 1.5e-14 0.08 0.08 0.07 0.08 1.3e-09 4.1e-09 7.2e-08 7.5e-09
21 PL gene expression Dcun1d1 0.07 0.04 4.7e-07 0.06 0.05 0.05 0.05 7.0e-07 1.6e-06 7.8e-06 2.0e-06
22 OFC alternative polyA NM_001395100.1 0.22 0.15 9.5e-03 0.04 0.06 -0.01 0.04 4.0e-02 1.5e-02 6.1e-01 4.1e-02
23 OFC alternative polyA NM_001395100.1 0.22 0.15 8.0e-03 0.04 0.06 -0.01 0.05 3.5e-02 1.2e-02 5.7e-01 2.9e-02
24 NAcc gene expression Dcun1d1 0.03 0.02 7.0e-04 0.02 0.02 0.01 0.02 3.4e-04 5.0e-04 1.1e-02 5.2e-04
25 Brain gene expression Dcun1d1 0.09 0.07 1.2e-05 0.05 0.06 0.04 0.05 1.0e-05 5.2e-06 5.9e-05 8.1e-06
26 Adipose mRNA stability Dcun1d1 0.04 0.04 9.2e-03 0 0 0 0 2.1e-01 9.1e-02 1.6e-01 3.0e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26
Bone: apparent density0.20.41.10.30.60.6-0.60.6-0.60.10.7-0.10.1-0.0-0.50.3-0.3-0.30.7-0.00.10.40.2-0.71.01.0-1.11.00.9
Area under the delay curve1.11.63.51.01.41.5-1.51.5-1.50.71.5-0.60.6-0.6-1.20.9-0.9-0.91.60.50.81.00.9-1.91.81.8-1.71.71.5
BMI with tail3.813.218.84.34.03.9-3.93.9-3.94.33.9-4.34.3-4.3-4.34.1-4.1-4.13.64.24.14.03.8-1.91.81.7-1.80.5-0.8
BMI without tail1.26.48.92.92.92.9-2.92.9-2.92.82.9-2.72.7-2.7-3.02.7-2.7-2.72.82.62.62.72.5-1.81.91.8-1.71.10.3
Body weight3.916.925.54.84.64.5-4.54.5-4.54.74.5-4.74.7-4.6-4.54.4-4.4-4.44.24.54.45.14.8-2.42.32.2-2.41.0-0.4
Weight adjusted by age0.10.20.5-0.6-0.6-0.50.5-0.50.5-0.5-0.60.5-0.50.50.7-0.50.50.5-0.5-0.5-0.6-0.5-0.60.3-0.3-0.30.3-0.00.1
Bone surface0.30.71.41.00.80.7-0.70.7-0.71.00.7-1.11.1-1.1-0.81.0-1.0-1.00.61.10.91.20.90.2-0.0-0.00.1-0.3-0.6
Bone volume0.10.20.40.50.50.5-0.50.5-0.50.40.5-0.40.4-0.4-0.40.5-0.5-0.50.40.40.40.60.3-0.20.30.3-0.20.30.1
Breakpoint value in progressive ratio session0.71.22.01.31.21.1-1.11.1-1.11.31.1-1.41.4-1.4-1.31.3-1.3-1.31.01.41.21.41.4-0.40.30.30.1-0.1-0.5
Number of licking bursts1.33.86.32.32.22.2-2.12.1-2.12.22.2-2.22.2-2.2-2.02.1-2.1-2.12.02.12.12.52.4-1.21.11.1-0.90.6-0.1
Context. condit. distance diff. score0.91.14.7-0.20.40.5-0.60.6-0.6-0.60.60.7-0.70.7-0.1-0.30.30.30.8-0.9-0.3-0.3-0.2-1.71.71.7-2.02.12.2
Locomotion velocity, session 10.80.94.00.60.0-0.10.2-0.20.20.9-0.2-1.01.0-1.1-0.20.7-0.7-0.7-0.41.20.80.60.71.4-1.4-1.41.4-1.8-2.0
Locomotion distance, session 11.41.84.41.40.80.6-0.60.6-0.61.80.6-1.81.8-1.9-1.11.6-1.6-1.60.32.01.61.11.51.1-1.0-1.00.8-1.6-2.1
Locomotion velocity, session 21.11.44.61.00.40.2-0.10.2-0.11.40.1-1.51.5-1.5-0.61.2-1.2-1.2-0.21.71.10.80.91.4-1.3-1.31.7-1.8-2.1
Locomotion distance, session 20.81.13.80.80.30.1-0.10.1-0.11.20.1-1.31.3-1.3-0.41.0-1.0-1.0-0.21.41.00.50.51.4-1.2-1.31.8-1.6-1.9
Locomotion velocity, session 30.00.00.2-0.1-0.2-0.20.2-0.20.2-0.0-0.2-0.00.0-0.00.1-0.10.10.1-0.20.0-0.1-0.00.20.4-0.4-0.40.1-0.4-0.4
Locomotion distance, session 30.00.00.40.1-0.0-0.10.1-0.10.10.2-0.1-0.20.2-0.20.10.2-0.2-0.2-0.20.20.1-0.2-0.30.3-0.3-0.30.6-0.3-0.4
Stereotopy head waving bouts, day 30.60.72.5-0.2-0.7-0.80.8-0.80.80.0-0.8-0.10.1-0.20.6-0.20.20.2-1.00.3-0.2-0.2-0.11.6-1.5-1.51.3-1.6-1.5
Stereotopy head waving duration, day 30.00.00.2-0.0-0.1-0.10.1-0.10.10.0-0.1-0.00.0-0.0-0.0-0.10.10.1-0.20.1-0.00.20.30.5-0.3-0.3-0.2-0.4-0.4
Locomotion velocity, session 70.30.41.60.4-0.0-0.10.1-0.10.10.6-0.1-0.60.6-0.7-0.00.3-0.3-0.3-0.30.70.40.50.31.0-0.9-0.90.9-1.1-1.3
Locomotion distance, session 70.70.91.9-1.1-1.0-1.01.0-1.01.0-1.0-1.01.0-1.01.01.2-1.01.01.0-1.0-1.0-0.9-1.2-1.40.5-0.5-0.51.0-0.10.2
Stereotopy head waving bouts, day 70.60.81.51.10.80.7-0.70.7-0.71.20.7-1.21.2-1.2-0.81.1-1.1-1.10.51.21.10.90.70.1-0.1-0.1-0.5-0.5-0.8
Stereotopy head waving duration, day 70.50.61.10.90.70.6-0.60.6-0.61.00.6-1.01.0-1.0-0.70.9-0.9-0.90.51.00.90.90.70.1-0.1-0.1-0.3-0.4-0.7
Locomotion velocity, session 81.31.52.11.21.41.4-1.41.4-1.41.11.4-1.01.0-1.0-1.41.3-1.3-1.31.50.91.30.70.7-1.31.41.4-1.41.10.8
Locomotion distance, session 80.71.01.41.11.21.2-1.21.2-1.21.01.2-1.01.0-0.9-1.01.1-1.1-1.11.10.91.00.80.8-0.91.01.0-0.90.80.5
Degree of sensitization distance1.01.11.8-1.2-1.1-1.01.0-1.01.0-1.3-1.01.3-1.31.31.2-1.21.21.2-0.9-1.3-1.2-1.2-1.30.2-0.2-0.20.50.20.6
Degree of sensitization stereotypy0.70.81.11.11.01.0-1.01.0-1.01.01.0-1.01.0-1.0-1.01.1-1.1-1.10.91.01.01.00.8-0.50.40.4-1.00.1-0.2
Conditioned locomotion1.92.33.7-1.8-1.6-1.51.4-1.41.4-1.9-1.41.9-1.91.91.7-1.81.81.8-1.2-1.9-1.8-1.6-1.70.3-0.3-0.30.50.30.8
Cocaine response after cond. corrected0.50.82.7-0.7-0.2-0.10.1-0.10.1-1.0-0.11.1-1.11.20.3-0.80.80.80.2-1.2-0.8-0.8-0.8-1.01.01.1-1.31.41.7
Cocaine response after cond. not corrected0.40.61.2-0.9-0.7-0.70.7-0.70.7-1.0-0.71.1-1.11.10.7-1.01.01.0-0.5-1.1-1.0-0.9-0.90.10.00.0-0.50.30.6
Cocaine response before conditioning0.91.15.10.1-0.5-0.70.8-0.70.70.5-0.8-0.60.6-0.60.20.1-0.1-0.1-1.00.80.00.20.32.0-1.9-1.91.4-2.2-2.3
Saline control response0.50.72.50.70.30.1-0.10.1-0.11.00.1-1.01.0-1.1-0.30.7-0.7-0.7-0.11.10.60.81.01.0-1.0-1.00.5-1.4-1.6
Bone: connectivity density1.11.72.81.51.41.3-1.31.3-1.31.61.3-1.61.6-1.6-1.51.6-1.6-1.61.21.61.51.71.6-0.30.50.4-0.6-0.0-0.5
Bone: cortical apparent density0.50.91.7-1.0-1.0-1.01.0-1.01.0-0.9-1.00.8-0.80.81.2-1.01.01.0-1.1-0.8-1.1-0.9-0.80.9-0.8-0.81.3-0.5-0.2
Bone: cortical area0.71.11.81.21.11.1-1.01.0-1.01.31.0-1.31.3-1.3-1.21.3-1.3-1.30.91.31.31.11.2-0.20.40.4-0.5-0.0-0.4
Bone: cortical porosity0.20.21.0-0.20.10.1-0.10.1-0.1-0.40.10.4-0.40.4-0.4-0.10.10.10.3-0.5-0.1-0.2-0.0-0.50.70.7-1.00.60.7
Bone: cortical porosity0.20.21.3-0.10.20.2-0.20.2-0.2-0.20.20.3-0.30.3-0.5-0.00.00.00.4-0.30.0-0.00.1-0.60.70.7-1.10.60.7
Bone: cortical thickness0.10.10.2-0.4-0.3-0.30.3-0.20.2-0.4-0.20.5-0.50.50.2-0.40.40.4-0.2-0.5-0.4-0.10.10.10.10.1-0.30.10.2
Bone: cortical thickness0.30.40.70.70.70.6-0.60.6-0.60.70.6-0.70.7-0.7-0.60.8-0.8-0.80.50.70.80.80.7-0.40.20.10.7-0.0-0.3
Bone: cortical tissue density0.50.81.8-0.9-1.0-1.01.0-1.01.0-0.8-1.00.8-0.80.71.2-0.90.90.9-1.0-0.7-1.0-0.8-0.70.8-0.8-0.81.4-0.5-0.3
Condit. Reinf. active minus inactive responses0.70.81.91.00.90.8-0.80.8-0.81.10.8-1.11.1-1.1-0.91.0-1.0-1.00.71.11.11.01.4-0.10.10.1-0.2-0.2-0.6
Condit. Reinf. active-inactive response ratio0.80.81.20.91.01.1-1.11.1-1.10.81.1-0.70.7-0.7-1.00.9-0.9-0.91.10.61.00.81.0-1.01.01.0-0.90.80.5
Condit. Reinf. active responses2.33.05.42.11.71.6-1.51.5-1.52.21.5-2.32.3-2.3-1.82.0-2.0-2.01.32.32.11.92.3-0.00.0-0.0-0.2-0.7-1.3
Condit. Reinf. inactive responses2.43.26.72.01.31.1-1.01.1-1.12.31.0-2.42.4-2.5-1.52.1-2.1-2.10.72.62.12.02.20.9-0.9-1.00.7-1.7-2.3
Incentive salience index mean0.60.81.51.10.90.8-0.80.8-0.81.20.8-1.21.2-1.2-0.91.0-1.0-1.00.61.21.11.01.2-0.0-0.0-0.0-0.1-0.4-0.7
Condit. Reinf. lever presses0.50.72.20.80.40.3-0.20.3-0.21.10.3-1.11.1-1.2-0.50.8-0.8-0.80.01.20.90.90.90.8-0.8-0.80.5-1.2-1.5
Condit. Reinf. active minus inactive responses0.30.51.20.80.50.4-0.40.4-0.41.00.4-1.01.0-1.0-0.70.9-0.9-0.90.21.10.80.40.60.6-0.5-0.50.5-0.8-1.1
Condit. Reinf. active-inactive response ratio0.10.20.6-0.4-0.1-0.10.1-0.10.1-0.5-0.10.5-0.50.50.2-0.30.30.30.0-0.6-0.4-0.7-0.5-0.50.50.5-0.40.70.8
Condit. Reinf. active responses1.42.05.01.50.90.7-0.60.7-0.61.90.7-2.02.0-2.0-1.21.5-1.5-1.50.32.11.51.31.51.1-1.1-1.11.2-1.7-2.2
Condit. Reinf. inactive responses3.45.110.82.51.71.4-1.31.4-1.33.01.3-3.13.1-3.2-2.02.5-2.5-2.50.93.32.42.82.71.3-1.2-1.31.2-2.2-3.0
Condit. Reinf. lever presses1.52.23.01.71.71.7-1.71.7-1.71.71.7-1.71.7-1.6-1.71.7-1.7-1.71.61.61.71.41.3-1.01.01.0-0.90.50.0
Condit. Reinf. lever reinforcers received1.41.94.31.61.00.8-0.80.8-0.81.90.8-1.91.9-2.0-1.21.5-1.5-1.50.52.11.51.31.50.9-0.9-0.91.0-1.5-2.0
Conditioned reinforcement - actives0.41.64.3-0.6-1.1-1.31.3-1.31.3-0.2-1.30.1-0.10.00.7-0.60.60.6-1.50.1-0.6-0.8-0.82.1-2.0-2.02.0-2.1-2.0
Conditioned reinforcement - inactives0.41.21.9-1.1-1.2-1.21.3-1.21.2-1.0-1.21.0-1.00.90.9-1.11.11.1-1.2-0.9-1.1-1.0-1.01.2-1.0-1.01.4-0.8-0.5
Conditioned locomotion0.40.72.50.70.20.00.0-0.00.01.0-0.0-1.11.1-1.2-0.20.9-0.9-0.9-0.31.20.7-0.2-0.20.8-1.0-1.00.7-1.3-1.6
Patch foraging indifference point 0 sec1.85.16.92.32.62.6-2.62.6-2.62.12.6-2.02.0-1.9-2.42.3-2.3-2.32.61.82.42.12.3-2.22.12.1-2.11.61.0
Patch foraging indifference point AUC0.10.20.70.0-0.2-0.30.3-0.30.30.2-0.3-0.30.2-0.30.30.0-0.0-0.0-0.40.30.00.30.10.7-0.8-0.80.7-0.8-0.9
Delay disc. indifference point, 0s delay0.60.61.5-0.5-0.8-0.90.9-0.90.9-0.3-0.90.2-0.20.20.8-0.70.70.7-1.0-0.1-0.6-0.5-0.51.2-1.2-1.20.7-1.1-1.0
Delay disc. indifference point, 16s delay0.91.23.30.91.21.3-1.31.3-1.30.71.3-0.70.6-0.6-0.91.0-1.0-1.01.30.51.10.80.7-1.81.41.4-1.41.31.1
Delay disc. indifference point, 2s delay1.11.22.60.91.21.3-1.31.3-1.30.71.3-0.60.6-0.6-1.10.7-0.7-0.71.40.50.61.01.0-1.31.41.4-1.61.31.1
Delay disc. indifference point, 24s delay0.20.31.5-0.20.10.2-0.30.2-0.2-0.40.20.4-0.50.50.10.0-0.0-0.00.4-0.60.2-0.3-0.4-1.10.90.9-0.61.11.2
Delay disc. indifference point, 4s delay1.31.41.91.21.31.3-1.41.3-1.41.11.3-1.01.0-1.0-1.31.1-1.1-1.11.40.91.11.41.4-1.21.11.1-1.10.80.5
Delay disc. indifference point, 8s delay0.30.62.50.10.50.6-0.70.6-0.6-0.20.60.3-0.30.3-0.3-0.00.00.00.8-0.4-0.30.1-0.1-1.31.41.4-1.11.61.6
Indifference point function ln k0.30.82.90.20.70.8-0.90.9-0.9-0.10.90.2-0.10.2-0.80.2-0.2-0.21.1-0.30.2-0.2-0.1-1.41.71.7-1.21.71.7
Indifference point function log k0.30.82.90.20.70.8-0.90.9-0.9-0.10.90.2-0.10.2-0.80.2-0.2-0.21.1-0.30.2-0.2-0.1-1.41.71.7-1.21.71.7
Patch foraging total patch changes 0 sec1.33.95.32.12.22.3-2.32.3-2.31.92.3-1.81.8-1.7-2.22.0-2.0-2.02.31.72.21.92.2-1.81.81.8-1.81.30.8
Patch foraging total patch changes 12 sec0.10.10.4-0.4-0.3-0.20.2-0.20.2-0.4-0.20.4-0.40.50.6-0.20.20.2-0.1-0.5-0.20.00.1-0.30.10.1-0.10.30.4
Patch foraging total patch changes 18 sec0.40.91.61.11.01.0-1.01.0-1.01.11.0-1.11.1-1.1-1.01.1-1.1-1.10.91.11.01.11.3-0.50.40.4-0.60.1-0.2
Patch foraging total patch changes 24 sec1.24.05.12.32.32.3-2.22.2-2.22.22.2-2.12.1-2.1-2.12.1-2.1-2.12.12.02.22.12.1-1.51.41.4-1.80.90.2
Patch foraging total patch changes 6 sec0.91.52.51.31.31.4-1.41.4-1.41.21.4-1.11.1-1.1-1.21.3-1.3-1.31.41.01.41.61.6-1.01.01.0-1.50.70.4
Patch foraging time to switch 0 sec0.20.81.5-1.1-0.9-0.90.9-0.90.9-1.1-0.91.1-1.11.11.0-0.90.90.9-0.8-1.1-1.0-1.2-1.20.2-0.3-0.30.60.10.4
Patch foraging water rate 0 sec0.00.00.10.00.10.1-0.10.1-0.1-0.00.10.1-0.10.1-0.0-0.30.30.30.1-0.1-0.20.20.3-0.00.20.2-0.20.20.2
Patch foraging water rate 12 sec0.00.10.70.1-0.1-0.20.2-0.20.20.3-0.2-0.30.3-0.3-0.0-0.00.00.0-0.30.4-0.00.20.50.7-0.6-0.60.0-0.8-0.8
Patch foraging water rate 18 sec0.10.30.70.70.50.4-0.40.4-0.40.80.4-0.80.8-0.8-0.60.4-0.4-0.40.30.90.40.80.80.5-0.3-0.3-0.0-0.6-0.8
Patch foraging water rate 24 sec0.20.31.40.70.50.4-0.40.4-0.40.80.4-0.80.8-0.8-0.40.3-0.3-0.30.30.80.31.01.20.4-0.2-0.2-0.5-0.4-0.6
Patch foraging water rate 6 sec0.00.00.20.1-0.0-0.00.0-0.00.00.2-0.0-0.20.2-0.2-0.1-0.10.10.1-0.10.2-0.10.10.10.4-0.3-0.3-0.3-0.4-0.4
Seeking ratio, delayed vs. immediate footshock2.53.55.52.12.12.0-2.02.0-2.02.12.0-2.02.0-2.0-2.32.2-2.2-2.22.02.02.21.71.8-1.41.31.3-1.50.70.1
Distance traveled before self-admin0.81.82.41.51.51.5-1.51.5-1.51.41.5-1.31.3-1.3-1.21.5-1.5-1.51.51.21.31.41.4-1.21.11.1-1.20.80.4
Distance traveled after self-admin2.23.95.92.42.22.1-2.12.1-2.12.42.1-2.42.4-2.4-2.02.4-2.4-2.41.92.42.31.81.8-1.10.90.9-1.10.4-0.4
Extensor digitorum longus weight4.417.424.04.84.74.6-4.54.5-4.54.74.5-4.64.6-4.6-4.84.6-4.6-4.64.34.54.64.94.8-2.52.52.5-2.51.2-0.2
Bone: elastic displacement1.11.46.4-0.50.30.4-0.50.5-0.5-0.90.51.0-1.01.1-0.3-0.40.40.40.9-1.2-0.4-0.7-0.8-1.92.02.0-1.52.32.5
Bone: elastic work1.62.04.5-1.6-1.0-0.80.7-0.80.7-1.9-0.72.0-2.02.01.0-1.51.51.5-0.4-2.1-1.5-1.8-1.8-0.91.01.0-0.61.52.1
Bone: endosteal estimation1.94.67.92.62.32.1-2.12.1-2.12.82.1-2.82.8-2.8-2.42.7-2.7-2.71.82.82.72.22.0-0.50.50.5-0.4-0.3-1.1
Bone: endosteal perimeter0.71.63.81.51.00.9-0.80.8-0.81.80.8-1.81.8-1.9-1.21.4-1.4-1.40.51.91.51.31.20.6-0.5-0.50.9-1.1-1.6
Epididymis fat weight1.57.610.33.23.13.1-3.13.1-3.13.03.1-3.03.0-2.9-3.23.0-3.0-3.02.92.92.83.23.1-1.81.81.8-1.51.00.1
Delta time in closed arm before/after self-admin0.30.30.70.60.60.6-0.60.6-0.60.50.6-0.50.5-0.5-0.50.6-0.6-0.60.60.50.50.80.8-0.50.40.40.00.30.1
Delta time in open arm before/after self-admin0.50.61.4-0.9-0.7-0.60.6-0.60.6-1.1-0.61.1-1.11.10.7-0.90.90.9-0.4-1.2-0.9-0.8-0.7-0.10.30.3-0.30.60.9
Diff in mean of infusions in LGA sessions0.61.12.51.01.21.2-1.21.2-1.20.81.2-0.70.7-0.7-1.10.9-0.9-0.91.30.60.70.80.8-1.21.31.3-1.61.10.8
Delay discount exponential model param1.21.73.7-1.0-1.4-1.51.5-1.51.5-0.7-1.50.6-0.60.51.2-0.90.90.9-1.6-0.4-0.8-0.9-0.81.9-1.9-1.91.8-1.8-1.6
Extinction: sum of active levers before priming0.10.10.40.1-0.1-0.10.1-0.10.10.2-0.1-0.30.3-0.30.20.0-0.0-0.0-0.20.30.10.20.20.4-0.5-0.50.6-0.5-0.6
Active lever presses in extinction session 60.10.10.20.30.40.4-0.40.4-0.40.20.4-0.10.1-0.1-0.40.1-0.1-0.10.40.10.10.40.3-0.30.40.4-0.10.40.3
Bone: final force1.42.34.91.81.61.5-1.51.5-1.51.81.5-1.81.8-1.8-1.61.7-1.7-1.71.31.81.71.92.2-0.50.50.4-0.6-0.1-0.6
Bone: final moment1.62.65.11.91.81.7-1.71.7-1.71.81.7-1.81.8-1.8-1.81.8-1.8-1.81.61.81.82.02.3-0.80.80.8-0.90.3-0.3
Food consumed during 24 hour testing period0.71.31.71.31.31.3-1.31.3-1.31.21.3-1.21.2-1.2-1.21.3-1.3-1.31.21.11.30.90.8-1.00.90.9-0.70.70.3
Glucose0.30.62.4-0.5-0.7-0.70.7-0.70.7-0.4-0.70.4-0.40.30.7-0.50.50.5-0.8-0.3-0.5-1.2-1.30.9-0.8-0.81.5-0.7-0.6
Heart weight2.54.06.22.22.22.2-2.22.2-2.22.12.2-2.12.1-2.1-2.52.2-2.2-2.22.12.02.12.42.5-1.31.31.3-0.90.70.0
Delay discount hyperbolic model param1.31.73.5-1.0-1.4-1.51.5-1.51.5-0.7-1.50.6-0.60.51.2-0.90.90.9-1.6-0.4-0.8-1.0-0.91.9-1.8-1.81.8-1.7-1.5
Intermittent access intake day 1-15 change0.42.33.2-1.6-1.7-1.81.8-1.81.8-1.5-1.81.4-1.41.41.4-1.51.51.5-1.7-1.3-1.4-1.8-1.81.5-1.3-1.31.3-1.0-0.5
Intermittent access intake escalation0.31.92.6-1.4-1.5-1.61.6-1.61.6-1.3-1.61.2-1.21.21.3-1.41.41.4-1.6-1.1-1.2-1.5-1.51.4-1.2-1.21.3-1.0-0.6
Intermittent access intake escalation 20.20.41.0-0.7-0.7-0.80.8-0.80.8-0.6-0.80.6-0.50.50.5-0.60.60.6-0.7-0.5-0.5-1.0-1.00.6-0.5-0.50.5-0.4-0.3
Intermitt. access day 1 inactive lever presses0.00.30.5-0.7-0.7-0.70.7-0.70.7-0.6-0.70.6-0.60.60.5-0.50.50.5-0.7-0.6-0.4-0.5-0.50.6-0.5-0.50.4-0.5-0.3
Intermitt. access day 15 inactive lever presses0.21.32.1-1.2-1.4-1.41.4-1.41.4-1.1-1.41.0-1.01.00.8-0.90.90.9-1.4-0.9-0.9-0.6-0.61.4-1.3-1.31.4-1.2-0.9
Intermitt. access escalation Index0.10.30.6-0.7-0.6-0.50.5-0.50.5-0.8-0.50.8-0.80.80.5-0.70.70.7-0.3-0.8-0.8-0.0-0.00.2-0.1-0.10.10.10.3
Intermittent access day 1 total infusions1.34.08.1-1.6-2.2-2.32.3-2.32.3-1.1-2.31.0-1.00.92.2-1.41.41.4-2.6-0.7-1.5-1.4-1.42.8-2.8-2.82.3-2.6-2.2
Intermittent access day 15 total infusions2.04.98.9-1.9-2.4-2.62.6-2.62.6-1.4-2.61.3-1.31.22.2-1.71.71.7-2.8-1.0-1.7-1.8-1.83.0-2.9-2.92.7-2.7-2.2
Intermittent access terminal intake (last 3 days)3.25.79.2-2.1-2.6-2.82.8-2.82.8-1.6-2.81.5-1.41.32.4-1.81.81.8-3.0-1.2-1.8-2.3-2.33.0-3.0-3.02.8-2.7-2.2
Intermittent access total infusions2.83.39.2-1.0-1.8-2.02.0-2.02.0-0.5-2.00.3-0.30.21.6-0.80.80.8-2.3-0.0-0.9-0.8-0.82.9-3.0-3.02.5-3.0-2.8
Intermittent access day 1 locomotion0.50.93.70.1-0.5-0.60.7-0.70.70.5-0.7-0.60.6-0.60.60.2-0.2-0.2-1.00.80.1-0.4-0.41.5-1.7-1.71.6-1.8-1.9
Intermittent access day 15 total locomotion0.20.82.21.10.70.5-0.50.5-0.51.30.5-1.41.4-1.4-0.71.1-1.1-1.10.21.51.20.00.00.3-0.5-0.50.3-0.8-1.2
Intermittent access total locomotion0.70.82.60.90.40.2-0.20.2-0.21.20.2-1.31.3-1.4-0.21.0-1.0-1.0-0.21.50.90.10.10.8-1.0-1.00.7-1.3-1.6
Intermittent access standard deviation0.10.40.6-0.8-0.8-0.80.8-0.80.8-0.8-0.80.8-0.80.80.5-0.60.60.6-0.7-0.7-0.6-0.5-0.50.5-0.5-0.50.3-0.4-0.1
Left kidney weight0.32.74.21.51.92.0-2.02.0-2.01.22.0-1.11.1-1.1-1.61.4-1.4-1.42.10.91.21.51.4-2.02.02.0-1.61.81.4
Right kidney weight1.06.910.02.73.03.1-3.13.1-3.12.33.1-2.12.1-2.1-3.02.5-2.5-2.53.21.92.43.02.9-2.72.72.7-2.22.11.4
Cocaine induced anxiety1.12.94.11.81.91.9-1.91.9-1.91.81.8-1.71.7-1.7-2.02.0-2.0-2.01.91.62.01.11.1-1.71.51.4-1.41.00.5
Post-drug Anxiety1.01.22.11.21.21.2-1.21.2-1.21.11.2-1.01.1-1.0-1.51.1-1.1-1.11.21.01.11.31.3-0.90.90.9-0.70.50.2
Baseline Anxiety1.11.83.1-1.5-1.4-1.41.4-1.41.4-1.6-1.31.6-1.61.61.4-1.81.81.8-1.2-1.6-1.7-0.4-0.41.1-0.8-0.81.0-0.40.0
Tail length0.10.41.10.40.60.7-0.70.7-0.70.30.7-0.20.2-0.2-0.40.4-0.4-0.40.80.10.30.90.9-0.70.80.8-1.00.80.7
Length with tail0.73.27.22.02.02.0-2.02.0-2.01.82.0-1.81.7-1.7-1.71.7-1.7-1.71.91.71.72.72.6-1.21.21.2-1.60.80.2
Length without tail1.58.012.93.23.13.1-3.13.1-3.13.13.1-3.13.1-3.1-2.93.1-3.1-3.12.83.03.13.63.4-1.81.61.5-2.20.8-0.2
Times rat made contact with spout0.20.20.40.50.50.4-0.40.4-0.40.60.4-0.60.6-0.6-0.40.6-0.6-0.60.30.60.60.10.0-0.10.10.1-0.2-0.0-0.2
Lifetime Intake2.83.59.4-1.1-1.9-2.12.1-2.12.1-0.6-2.10.4-0.40.31.7-1.01.01.0-2.4-0.1-1.0-0.8-0.82.9-3.1-3.12.6-3.0-2.8
Liver weight, left0.20.32.3-0.2-0.4-0.50.5-0.50.5-0.0-0.5-0.00.0-0.00.5-0.20.20.2-0.60.1-0.3-0.3-0.50.8-0.8-0.81.5-0.8-0.7
Liver weight, right0.20.30.5-0.7-0.6-0.60.6-0.60.6-0.7-0.60.7-0.70.70.5-0.60.60.6-0.6-0.7-0.6-0.5-0.70.5-0.3-0.30.3-0.2-0.0
Locomotor activity0.40.61.0-0.8-0.9-0.90.9-0.90.9-0.7-0.90.7-0.70.70.6-0.80.80.8-0.8-0.6-0.8-0.2-0.51.0-0.8-0.80.8-0.8-0.5
Locomotor testing distance0.71.73.81.51.00.9-0.80.9-0.81.70.9-1.71.7-1.8-1.51.3-1.3-1.30.61.81.31.91.80.8-0.6-0.60.4-1.3-1.7
Locomotor testing rearing0.10.20.6-0.3-0.4-0.40.4-0.40.4-0.3-0.40.3-0.30.30.2-0.50.50.5-0.4-0.2-0.5-0.1-0.10.8-0.5-0.50.6-0.6-0.5
Locomotion in novel chamber1.41.92.71.61.61.5-1.51.5-1.51.61.5-1.61.6-1.6-1.41.5-1.5-1.51.41.51.41.51.5-0.70.80.7-1.20.4-0.1
Locomotion in novel chamber post-restriction0.00.00.10.00.00.0-0.00.0-0.0-0.00.00.0-0.00.0-0.1-0.20.20.20.0-0.0-0.10.30.40.1-0.0-0.0-0.1-0.1-0.1
Fecal boli incidents, locomotor time 10.61.52.3-1.5-1.4-1.31.3-1.31.3-1.5-1.31.5-1.51.51.3-1.41.41.4-1.2-1.5-1.5-1.1-1.30.9-0.6-0.60.7-0.20.2
Change in fecal boli incidents, locomotor task1.01.12.01.31.11.0-1.01.0-1.01.41.0-1.41.4-1.4-1.01.1-1.1-1.10.81.41.31.21.3-0.50.10.1-0.1-0.3-0.6
Time >=10cm from walls, locomotor time 10.10.20.8-0.3-0.5-0.50.5-0.50.5-0.2-0.50.2-0.20.20.60.0-0.0-0.0-0.5-0.10.1-0.1-0.10.3-0.7-0.70.9-0.6-0.5
Bouts of movement, locomotor time 10.50.71.9-1.0-0.9-0.90.9-0.90.9-1.0-0.91.0-1.01.00.8-0.50.50.5-0.8-1.0-0.4-1.4-1.30.3-0.3-0.30.5-0.10.2
Total resting periods, locomotor time 11.31.52.9-1.5-1.3-1.21.2-1.21.2-1.6-1.21.6-1.61.61.2-1.11.11.1-1.1-1.6-1.0-1.7-1.60.3-0.2-0.20.50.20.7
Rest time, locomotor task time 10.71.22.7-1.3-1.1-1.11.1-1.11.1-1.2-1.11.3-1.21.21.1-1.31.31.3-1.0-1.2-1.1-1.6-1.60.8-0.4-0.40.3-0.00.3
Distance moved, locomotor task time 10.82.33.51.81.61.6-1.61.6-1.61.91.5-1.91.8-1.8-1.61.7-1.7-1.71.41.81.81.91.8-1.00.50.5-0.50.0-0.5
Vertical activity count, locomotor time 10.53.25.02.12.02.0-2.02.0-2.02.02.0-2.02.0-2.0-2.01.8-1.8-1.81.91.91.62.22.2-1.21.11.1-0.40.6-0.0
Time >=10cm from walls, locomotor time 20.20.50.7-0.8-0.8-0.80.8-0.80.8-0.7-0.90.6-0.60.60.8-0.50.50.5-0.8-0.6-0.4-0.7-0.80.4-0.7-0.70.6-0.5-0.3
Bouts of movement, locomotor time 20.82.63.9-1.9-1.7-1.71.7-1.71.7-1.9-1.71.9-1.91.91.5-1.81.81.8-1.5-1.9-1.6-2.0-1.81.1-0.7-0.60.8-0.20.3
Total resting periods, locomotor time 20.51.92.9-1.6-1.5-1.41.4-1.41.4-1.7-1.41.7-1.71.71.2-1.71.71.7-1.3-1.7-1.5-1.6-1.51.0-0.5-0.50.7-0.10.4
Rest time, locomotor task time 20.10.10.2-0.3-0.2-0.20.1-0.10.1-0.4-0.10.4-0.40.40.1-0.30.30.3-0.1-0.5-0.3-0.4-0.30.10.30.30.10.40.5
Distance moved, locomotor task time 20.70.91.91.20.90.9-0.80.8-0.81.30.8-1.31.3-1.4-0.91.1-1.1-1.10.71.41.11.01.0-0.3-0.1-0.1-0.5-0.5-0.8
Vertical activity count, locomotor time 20.30.81.81.00.60.5-0.50.5-0.51.20.5-1.31.3-1.3-0.51.1-1.1-1.10.31.30.81.01.00.2-0.6-0.60.5-0.9-1.2
Light reinforcement 10.31.62.2-1.4-1.5-1.41.4-1.41.4-1.4-1.41.3-1.31.31.5-1.41.41.4-1.3-1.3-1.4-0.8-0.81.1-1.0-1.01.0-0.7-0.3
Light reinforcement 20.20.50.9-0.8-0.9-0.80.8-0.80.8-0.8-0.80.8-0.80.80.9-0.70.70.7-0.8-0.7-0.7-0.5-0.70.6-0.6-0.60.6-0.4-0.1
Bone: marrow area2.15.08.32.72.42.2-2.22.2-2.22.92.2-2.92.9-2.9-2.52.7-2.7-2.71.92.92.82.32.1-0.70.60.6-0.5-0.1-1.0
Bone: maximum diameter0.81.63.21.51.31.1-1.11.1-1.11.71.1-1.71.7-1.8-1.41.6-1.6-1.60.91.81.71.21.20.10.00.00.1-0.5-1.0
Bone: maximum force0.40.81.71.10.90.9-0.90.9-0.91.10.9-1.11.1-1.1-0.91.0-1.0-1.00.81.11.01.11.3-0.30.30.2-0.3-0.0-0.4
Bone: maximum moment0.51.01.81.11.11.1-1.11.1-1.11.11.1-1.01.0-1.0-1.01.1-1.1-1.11.01.01.01.21.4-0.60.60.6-0.70.30.0
Mean time between licks in bursts0.00.10.1-0.2-0.1-0.10.1-0.10.1-0.3-0.00.3-0.30.30.3-0.30.30.3-0.0-0.4-0.30.10.1-0.20.20.2-0.00.30.4
Mean num. licks in bursts0.82.14.7-1.7-1.6-1.61.6-1.61.6-1.6-1.61.6-1.51.51.4-1.51.51.5-1.5-1.5-1.5-2.2-2.10.9-0.8-0.80.5-0.40.1
Cd content in liver1.31.52.8-1.2-1.4-1.41.4-1.41.4-1.0-1.40.9-0.90.91.3-1.01.01.0-1.5-0.8-1.1-1.1-1.01.5-1.3-1.31.7-1.1-0.8
Co content in liver1.11.32.01.21.21.2-1.21.2-1.21.21.2-1.21.2-1.2-1.31.4-1.4-1.41.21.21.31.11.1-0.90.80.8-0.40.40.1
Cu content in liver0.20.20.40.60.50.5-0.50.5-0.50.60.5-0.70.7-0.7-0.40.6-0.6-0.60.40.70.70.70.5-0.10.10.1-0.0-0.1-0.3
Fe content in liver0.40.50.9-0.8-0.7-0.60.6-0.60.6-0.9-0.60.9-0.90.90.7-0.90.90.9-0.5-0.9-0.9-0.8-0.60.1-0.1-0.10.10.20.4
K content in liver0.60.61.4-0.9-0.6-0.50.5-0.50.5-1.0-0.51.0-1.01.10.9-1.01.01.0-0.4-1.1-1.2-0.8-0.7-0.30.30.3-0.70.71.0
Mg content in liver0.40.41.8-0.4-0.10.0-0.10.1-0.1-0.70.10.7-0.70.80.4-0.60.60.60.2-0.8-0.6-0.4-0.3-0.90.80.9-1.21.21.3
Mn content in liver1.61.83.1-1.6-1.4-1.31.3-1.31.3-1.7-1.31.7-1.71.71.5-1.51.51.5-1.1-1.7-1.7-1.8-1.70.3-0.3-0.2-0.20.20.7
Na content in liver0.40.51.20.80.50.4-0.40.4-0.40.90.4-0.90.9-0.9-0.30.8-0.8-0.80.21.00.70.91.10.3-0.4-0.4-0.0-0.6-0.8
Rb content in liver0.40.41.20.40.60.7-0.70.7-0.70.10.7-0.10.1-0.0-0.60.2-0.2-0.20.9-0.00.30.40.2-1.11.11.1-0.71.01.0
Se content in liver2.63.14.2-1.9-2.0-2.02.0-2.02.0-1.7-2.01.7-1.71.62.0-1.91.91.9-2.0-1.6-2.0-2.0-2.01.5-1.5-1.41.2-1.0-0.5
Sr content in liver0.40.41.4-0.3-0.5-0.60.7-0.70.7-0.1-0.60.1-0.10.00.4-0.30.30.3-0.80.0-0.30.00.11.2-1.0-1.00.7-1.0-1.0
Zn content in liver0.20.20.30.50.50.5-0.60.5-0.50.50.6-0.50.5-0.4-0.30.4-0.4-0.40.50.40.40.50.6-0.40.40.4-0.30.30.2
Bone: minimum diameter1.73.25.02.22.01.9-1.81.8-1.82.21.8-2.22.2-2.2-2.12.2-2.2-2.21.62.22.21.71.5-0.60.70.7-0.80.1-0.6
Time in familiar zone, hab. session 10.10.10.3-0.0-0.2-0.20.3-0.30.30.1-0.3-0.10.1-0.20.20.1-0.1-0.1-0.30.20.1-0.2-0.40.4-0.5-0.50.6-0.5-0.5
Time in novel zone, hab. session 10.10.10.2-0.2-0.3-0.30.3-0.30.3-0.2-0.30.2-0.20.20.2-0.40.40.4-0.3-0.2-0.40.00.20.4-0.3-0.30.4-0.3-0.2
Total zone transitions, hab. session 11.21.72.71.51.41.4-1.41.4-1.41.41.4-1.41.4-1.4-1.61.6-1.6-1.61.31.41.51.31.2-0.70.80.8-0.60.3-0.1
Total locomotion distance, hab. session 10.60.91.61.00.80.7-0.70.7-0.71.10.7-1.21.2-1.2-1.01.2-1.2-1.20.61.21.11.21.30.2-0.1-0.1-0.0-0.6-0.9
Locomotion velocity, hab. session 10.71.12.01.21.01.0-1.01.0-1.01.20.9-1.21.2-1.2-1.21.3-1.3-1.30.91.21.31.31.4-0.20.30.2-0.5-0.2-0.5
Time in familiar zone, hab. session 23.64.15.5-2.3-2.3-2.22.2-2.22.2-2.3-2.22.2-2.22.22.2-2.32.32.3-2.1-2.2-2.3-2.1-2.11.3-1.3-1.31.1-0.7-0.0
Time in novel zone, hab. session 23.23.54.72.12.12.1-2.12.1-2.12.02.1-2.02.0-2.0-2.12.2-2.2-2.22.01.92.11.81.9-1.31.31.3-1.00.80.2
Total zone transitions, hab. session 22.12.75.01.91.51.4-1.41.4-1.42.11.4-2.22.2-2.2-1.72.0-2.0-2.01.12.22.01.81.80.1-0.1-0.10.3-0.8-1.4
Total locomotion distance, hab. session 21.11.42.81.31.00.9-0.80.8-0.81.50.8-1.61.6-1.6-1.11.4-1.4-1.40.61.61.41.51.70.4-0.4-0.40.2-0.9-1.3
Locomotion velocity, hab. session 21.31.83.51.51.00.9-0.80.8-0.81.70.8-1.81.8-1.8-1.21.5-1.5-1.50.61.91.51.71.90.7-0.6-0.60.5-1.2-1.7
Novel to familiar place preference ratio0.81.14.00.20.70.9-0.90.9-0.9-0.20.90.3-0.30.4-0.60.0-0.0-0.01.2-0.50.0-0.0-0.0-1.81.91.9-1.72.02.0
Novelty place preference1.01.34.70.10.80.9-1.00.9-1.0-0.31.00.4-0.40.5-0.70.0-0.0-0.01.2-0.6-0.0-0.0-0.0-1.92.02.0-2.02.12.2
Time in novel zone, NPP test1.41.75.40.51.11.3-1.31.3-1.30.01.30.1-0.10.2-1.00.3-0.3-0.31.6-0.30.30.20.2-2.22.32.3-2.22.32.2
Total zone transitions, NPP test0.81.25.00.5-0.1-0.30.3-0.30.30.9-0.3-1.01.0-1.1-0.10.7-0.7-0.7-0.61.20.70.80.81.6-1.6-1.71.7-2.0-2.2
Total locomotion distance, NPP test0.71.04.30.2-0.3-0.50.5-0.50.50.6-0.5-0.70.7-0.70.20.2-0.2-0.2-0.80.90.20.70.71.8-1.7-1.71.4-2.0-2.1
Locomotion velocity, NPP test0.91.34.9-0.2-0.8-0.91.0-1.01.00.2-1.0-0.30.3-0.40.6-0.20.20.2-1.20.5-0.20.40.42.1-2.0-2.01.8-2.2-2.2
Intraocular pressure0.71.11.5-1.2-1.2-1.21.2-1.21.2-1.2-1.21.2-1.21.21.1-1.21.21.2-1.1-1.1-1.1-0.8-0.80.9-0.8-0.80.9-0.5-0.2
Delta distance traveled before/after self-admin0.30.30.60.60.50.5-0.40.4-0.40.80.4-0.80.8-0.8-0.60.7-0.7-0.70.30.80.70.10.1-0.00.00.0-0.1-0.2-0.4
Delta ambulatory time before/after self-admin0.20.30.60.70.60.6-0.50.5-0.50.80.5-0.80.8-0.8-0.70.8-0.8-0.80.50.80.80.20.2-0.10.20.1-0.2-0.0-0.3
Parametrial fat weight0.41.02.11.20.90.8-0.80.8-0.81.30.7-1.41.4-1.4-1.11.2-1.2-1.20.61.41.21.31.10.1-0.2-0.20.3-0.6-1.0
Pavlov. Cond. lever latency0.50.62.1-0.7-0.3-0.20.1-0.20.1-1.0-0.11.0-1.01.10.3-0.80.80.80.1-1.1-0.8-0.9-0.7-0.80.90.9-0.91.21.4
Pavlov. Cond. magazine entry latency2.22.84.52.01.71.6-1.61.6-1.62.11.6-2.12.1-2.1-1.72.0-2.0-2.01.42.12.02.12.0-0.50.40.3-0.2-0.2-0.8
Pavlov. Cond. change in total contacts0.30.40.90.70.40.3-0.30.3-0.30.80.3-0.90.9-0.9-0.40.6-0.6-0.60.10.90.70.60.50.5-0.5-0.50.6-0.7-0.9
Pavlov. Cond. index score1.82.24.61.71.31.1-1.11.1-1.12.01.1-2.12.1-2.1-1.31.8-1.8-1.80.82.21.81.81.70.3-0.5-0.50.6-1.0-1.6
Pavlov. Cond. latency score1.31.73.71.51.00.8-0.80.8-0.81.80.8-1.81.8-1.9-1.01.5-1.5-1.50.51.91.51.61.40.5-0.7-0.70.8-1.2-1.7
Pavlov. Cond. lever contacts0.70.92.11.00.60.4-0.40.4-0.41.20.4-1.31.3-1.3-0.61.0-1.0-1.00.21.41.01.21.00.6-0.7-0.80.8-1.1-1.4
Pavlov. Cond. magazine entry number3.44.36.6-2.5-2.2-2.12.1-2.12.1-2.6-2.12.6-2.62.62.1-2.52.52.5-1.8-2.5-2.5-2.4-2.40.8-0.7-0.70.4-0.10.7
Pavlov. Cond. intertrial magazine entries0.80.91.6-1.1-1.0-1.01.0-1.01.0-1.2-1.01.1-1.11.11.0-1.21.21.2-0.9-1.1-1.1-1.3-0.90.4-0.4-0.40.3-0.10.2
Pavlov. Cond. lever-magazine prob. diff.1.62.04.11.61.21.1-1.01.0-1.01.91.0-2.01.9-2.0-1.21.7-1.7-1.70.72.01.61.81.70.3-0.4-0.40.4-0.9-1.5
Pavlov. Cond. response bias2.53.15.12.11.81.7-1.71.7-1.72.21.7-2.32.3-2.3-1.72.1-2.1-2.11.42.32.12.12.0-0.40.30.3-0.1-0.2-0.9
Pavlov. Cond. lever latency3.24.56.4-2.5-2.4-2.32.3-2.32.3-2.5-2.32.5-2.52.52.4-2.52.52.5-2.1-2.5-2.4-2.2-2.21.1-1.0-1.00.9-0.30.4
Pavlov. Cond. magazine entry latency2.33.34.91.82.12.2-2.22.2-2.21.52.2-1.41.4-1.3-2.01.7-1.7-1.72.21.21.71.21.0-2.12.22.2-1.91.91.4
Pavlov. Cond. change in total contacts1.94.66.92.62.32.2-2.22.2-2.22.62.2-2.62.6-2.6-2.42.5-2.5-2.52.02.62.52.42.3-0.80.70.7-0.7-0.0-0.8
Pavlov. Cond. index score4.67.29.83.13.13.0-3.03.0-3.03.13.0-3.03.0-3.0-3.13.0-3.0-3.02.82.93.02.72.4-1.71.71.7-1.50.9-0.0
Pavlov. Cond. latency score3.96.38.52.92.92.8-2.82.8-2.82.92.8-2.82.8-2.8-2.82.9-2.9-2.92.62.72.82.42.2-1.71.61.6-1.30.90.0
Pavlov. Cond. lever contacts3.34.97.22.62.42.3-2.32.3-2.32.72.3-2.72.7-2.7-2.42.6-2.6-2.62.12.62.62.42.3-1.00.90.9-0.80.2-0.6
Pavlov. Cond. magazine entry number5.47.09.7-2.9-3.1-3.13.1-3.13.1-2.7-3.12.6-2.62.53.0-2.82.82.8-3.1-2.4-2.8-2.2-1.92.5-2.5-2.41.9-1.9-1.0
Pavlov. Cond. intertrial magazine entries0.10.20.9-0.1-0.4-0.40.4-0.40.40.1-0.4-0.10.1-0.20.2-0.00.00.0-0.50.2-0.10.10.20.8-0.8-0.80.5-0.9-0.9
Pavlov. Cond. lever-magazine prob. diff.4.36.69.03.02.92.8-2.82.8-2.83.02.8-2.92.9-2.9-2.92.9-2.9-2.92.62.82.92.52.3-1.61.61.5-1.40.8-0.1
Pavlov. Cond. response bias3.75.27.12.72.62.5-2.52.5-2.52.62.5-2.62.6-2.5-2.62.5-2.5-2.52.42.52.52.32.1-1.41.41.4-1.20.7-0.1
Time in closed arm before self-admin0.30.51.0-0.9-0.8-0.80.8-0.80.8-0.9-0.70.9-0.90.90.6-0.90.90.9-0.7-0.9-0.7-1.0-1.00.3-0.2-0.2-0.3-0.00.2
Time in closed arm after self-admin0.30.40.7-0.7-0.6-0.60.5-0.60.5-0.7-0.50.7-0.70.70.8-0.80.80.8-0.5-0.7-0.8-0.6-0.60.2-0.2-0.20.20.10.3
Time in open arm before self-admin3.84.66.12.52.52.4-2.42.4-2.42.32.5-2.32.3-2.2-2.22.4-2.4-2.42.32.12.32.32.3-1.81.51.5-1.01.00.3
Time in open arm after self-admin0.40.40.70.60.70.7-0.80.8-0.80.40.8-0.40.4-0.4-0.70.7-0.7-0.70.80.30.60.60.7-0.80.80.8-0.50.70.6
Bone: periosteal estimation1.73.96.42.42.12.0-1.91.9-1.92.51.9-2.52.5-2.5-2.22.5-2.5-2.51.72.52.52.01.9-0.50.60.5-0.5-0.1-0.9
Bone: periosteal perimeter0.30.51.30.80.40.3-0.30.3-0.30.90.3-1.01.0-1.0-0.70.8-0.8-0.80.11.10.80.70.80.7-0.5-0.50.6-0.9-1.1
Bone: post-yield work0.20.30.60.60.50.4-0.40.4-0.40.80.4-0.80.8-0.8-0.30.6-0.6-0.60.20.80.60.50.50.1-0.1-0.10.4-0.2-0.5
Progressive ratio test 1 active lever presses1.01.88.20.2-0.6-0.80.9-0.90.90.7-0.9-0.80.8-0.90.40.2-0.2-0.2-1.31.10.10.30.32.2-2.4-2.42.1-2.7-2.9
Progressive ratio test 1 breakpoint1.12.09.00.2-0.6-0.80.9-0.90.90.8-0.9-0.90.9-1.00.40.3-0.3-0.3-1.31.20.20.40.42.3-2.5-2.52.1-2.9-3.0
Progressive ratio test 1 inactive lever presses0.92.35.9-1.0-1.5-1.71.7-1.71.7-0.6-1.70.5-0.50.41.3-0.90.90.9-1.9-0.3-1.0-0.6-0.62.4-2.4-2.42.3-2.4-2.2
Progressive ratio test 2 active lever presses2.23.29.8-0.7-1.5-1.71.8-1.81.8-0.1-1.8-0.10.1-0.21.5-0.70.70.7-2.20.4-0.7-0.6-0.62.8-3.1-3.12.7-3.1-3.0
Progressive ratio test 2 breakpoint2.43.09.4-0.7-1.5-1.71.8-1.71.8-0.1-1.7-0.10.1-0.21.5-0.60.60.6-2.10.4-0.6-0.7-0.72.8-3.0-3.02.7-3.1-3.0
Progressive ratio test 2 inactive lever presses0.72.45.3-1.1-1.6-1.81.8-1.81.8-0.8-1.80.6-0.60.61.2-1.01.01.0-1.9-0.4-1.0-1.1-1.12.3-2.2-2.22.2-2.2-1.9
Incentive Sensitization - Responses0.41.23.1-0.6-1.0-1.21.2-1.21.2-0.2-1.20.1-0.10.01.1-0.40.40.4-1.40.1-0.5-1.1-1.11.6-1.8-1.81.7-1.7-1.6
Incentive Sensitization - Breakpoint0.61.33.2-0.6-1.1-1.21.2-1.21.3-0.2-1.20.1-0.10.11.1-0.50.50.5-1.50.0-0.5-1.1-1.11.7-1.8-1.81.8-1.7-1.6
Sum of active levers in priming session hrs 5-60.50.51.3-0.4-0.7-0.70.7-0.70.7-0.2-0.80.1-0.10.10.6-0.30.30.3-0.8-0.0-0.3-0.00.01.0-1.1-1.11.0-1.1-1.0
Progressive ratio0.10.21.50.0-0.2-0.30.3-0.30.30.2-0.3-0.20.2-0.2-0.10.2-0.2-0.2-0.40.30.1-0.3-0.30.5-0.6-0.61.2-0.7-0.8
Food seeking constrained by brief footshock2.12.65.21.71.81.8-1.81.9-1.91.51.9-1.51.5-1.5-2.01.5-1.5-1.51.81.41.62.22.3-1.21.31.3-1.20.90.4
Seeking ratio, punishment vs. effort0.51.13.40.81.11.2-1.21.2-1.20.61.2-0.50.5-0.5-0.90.6-0.6-0.61.30.40.71.41.3-1.21.31.3-1.81.21.0
Retroperitoneal fat weight2.19.214.63.63.23.0-3.03.0-3.03.83.0-3.83.8-3.8-3.43.7-3.7-3.72.63.83.63.43.1-1.00.80.8-0.6-0.3-1.4
Reaction time number correct0.72.66.7-1.0-1.6-1.71.8-1.81.8-0.5-1.80.4-0.40.31.4-1.11.11.1-2.0-0.1-1.1-0.7-0.72.6-2.5-2.52.3-2.5-2.3
Reaction time mean minus median0.85.29.72.02.52.6-2.72.7-2.71.52.7-1.41.4-1.3-2.32.0-2.0-2.02.81.11.91.51.7-3.13.02.9-2.92.72.2
Reaction time mean minus median AUC0.53.45.91.62.02.1-2.12.1-2.11.32.1-1.21.2-1.1-1.91.7-1.7-1.72.21.01.61.11.4-2.42.32.3-2.22.11.6
Reaction time num false alarms0.00.00.1-0.3-0.2-0.20.2-0.20.2-0.3-0.20.3-0.30.30.2-0.00.00.0-0.1-0.3-0.0-0.2-0.2-0.0-0.0-0.0-0.20.00.1
Reaction time num false alarms AUC0.10.20.3-0.5-0.5-0.50.5-0.50.5-0.4-0.50.4-0.40.40.4-0.20.20.2-0.5-0.4-0.2-0.3-0.40.4-0.4-0.40.4-0.4-0.2
Reaction time trials correct on left0.72.66.7-1.0-1.6-1.71.8-1.81.8-0.5-1.80.4-0.40.31.4-1.11.11.1-2.0-0.1-1.1-0.7-0.72.6-2.5-2.52.3-2.5-2.3
Reaction time trials on left0.72.46.2-1.0-1.5-1.71.7-1.71.7-0.5-1.70.4-0.40.31.3-1.01.01.0-1.9-0.2-1.1-0.7-0.72.5-2.4-2.42.2-2.4-2.2
Reaction time mean1.32.910.31.11.71.8-1.81.8-1.80.71.8-0.50.5-0.5-1.51.2-1.2-1.22.00.31.20.91.1-2.62.52.5-3.22.42.2
Reaction time mean AUC1.22.911.21.01.61.8-1.81.8-1.80.51.8-0.40.4-0.3-1.41.1-1.1-1.12.00.11.10.70.9-2.72.62.6-3.42.62.4
Median of all reaction times1.01.57.50.40.91.1-1.11.1-1.10.01.10.1-0.10.2-0.80.6-0.6-0.61.3-0.30.60.30.5-2.02.02.0-2.72.02.0
Reaction time omissions1.62.78.30.61.41.6-1.61.6-1.60.11.60.1-0.10.2-1.30.6-0.6-0.61.9-0.30.50.40.8-2.82.82.8-2.92.82.7
Reaction time false alarm rate0.10.20.50.10.30.4-0.40.4-0.4-0.00.40.1-0.10.1-0.30.4-0.4-0.40.5-0.10.40.30.1-0.70.60.6-0.70.60.7
Reaction time premature initiation rate3.24.98.3-2.7-2.3-2.22.1-2.12.1-2.8-2.12.9-2.92.92.4-2.52.52.5-1.9-2.9-2.5-2.8-2.70.6-0.4-0.40.60.41.2
Reaction time premature initiations2.06.17.9-2.8-2.8-2.72.7-2.72.7-2.7-2.72.6-2.62.62.8-2.72.72.7-2.6-2.5-2.7-2.7-2.61.9-1.7-1.71.8-1.0-0.2
Std. dev. reaction times1.96.412.62.22.82.9-2.92.9-2.91.72.9-1.61.6-1.5-2.62.2-2.2-2.23.11.32.21.82.0-3.33.23.2-3.62.92.3
Reaction time trials completed0.72.46.2-1.0-1.5-1.71.7-1.71.7-0.5-1.70.4-0.40.31.3-1.01.01.0-1.9-0.2-1.1-0.7-0.72.5-2.4-2.42.2-2.4-2.2
Reaction time trials AUC0.72.46.2-0.9-1.5-1.61.7-1.71.7-0.5-1.70.4-0.40.31.3-1.01.01.0-1.9-0.1-1.0-0.6-0.62.5-2.4-2.42.2-2.4-2.2
Run reversals in cocaine runway, females0.30.31.20.50.20.1-0.10.1-0.10.60.1-0.70.7-0.7-0.50.5-0.5-0.5-0.10.80.50.50.50.6-0.6-0.60.6-0.9-1.1
Run reversals in cocaine runway, males0.60.61.31.00.80.7-0.60.7-0.61.10.7-1.11.1-1.1-0.80.9-0.9-0.90.51.10.90.90.90.1-0.1-0.1-0.2-0.4-0.7
Latency to leave start box in cocaine runway0.30.41.50.40.70.7-0.70.7-0.70.10.8-0.10.1-0.0-0.8-0.00.00.00.8-0.10.20.10.1-1.01.21.2-0.61.21.1
Latency to leave start box in cocaine runway, F0.20.31.2-0.00.30.4-0.40.4-0.4-0.20.40.3-0.30.3-0.4-0.40.40.40.5-0.4-0.1-0.5-0.5-0.61.01.0-0.31.11.1
Latency to leave start box in cocaine runway, M0.60.61.10.60.80.9-0.90.9-0.90.40.9-0.40.4-0.3-0.80.5-0.5-0.51.00.30.40.80.8-1.11.01.0-0.91.00.8
Std. dev. time between licks in bursts0.50.92.40.91.11.1-1.11.1-1.10.71.1-0.70.7-0.7-0.90.8-0.8-0.81.10.60.81.51.6-1.01.00.9-0.60.80.6
Total sessions with >9 infusions1.92.35.8-1.0-1.5-1.71.7-1.71.7-0.5-1.70.4-0.40.31.4-0.80.80.8-1.9-0.2-0.9-0.8-0.82.3-2.4-2.42.2-2.4-2.2
Short access day 1 total inactive lever presses0.40.92.6-0.4-0.8-1.01.0-1.01.0-0.1-1.00.1-0.1-0.00.5-0.30.30.3-1.10.1-0.2-0.7-0.71.5-1.5-1.51.4-1.6-1.5
Short access day 10 total inactive lever presses0.10.81.30.70.91.0-1.01.0-1.00.51.0-0.50.5-0.5-0.90.8-0.8-0.81.10.40.80.50.5-1.11.21.2-1.01.10.9
Short access day 1 total infusions1.12.15.5-0.8-1.4-1.61.6-1.61.6-0.4-1.60.3-0.30.21.1-0.70.70.7-1.8-0.1-0.7-0.9-0.92.2-2.3-2.32.1-2.4-2.2
Short access day 10 total infusions1.52.47.4-0.8-1.4-1.61.7-1.61.7-0.3-1.60.2-0.20.11.2-0.70.70.7-1.90.1-0.7-0.3-0.32.5-2.6-2.62.2-2.7-2.5
Short access total infusions2.53.69.2-1.2-1.9-2.12.2-2.12.1-0.7-2.10.5-0.50.41.8-1.01.01.0-2.4-0.2-1.1-1.0-1.02.9-3.0-3.02.6-3.0-2.7
Short access day 1 locomotion0.71.12.11.31.00.9-0.90.9-0.91.40.9-1.41.4-1.4-1.21.4-1.4-1.40.71.41.40.80.8-0.20.10.0-0.1-0.3-0.8
Short access day 10 total locomotion0.10.50.90.90.80.8-0.70.7-0.70.90.7-0.90.9-0.9-0.61.0-1.0-1.00.60.91.00.50.5-0.50.30.3-0.20.1-0.2
Short access total locomotion0.40.62.40.70.20.1-0.00.1-0.01.00.1-1.11.1-1.1-0.20.8-0.8-0.8-0.21.20.80.30.30.7-1.0-1.01.0-1.3-1.5
One hour access (0.3 mA shock)0.70.83.40.1-0.4-0.60.6-0.60.60.5-0.6-0.60.6-0.60.60.1-0.1-0.1-0.90.70.1-0.1-0.11.4-1.6-1.71.1-1.8-1.9
Compulsive drug intake2.94.25.62.42.42.3-2.32.3-2.32.32.3-2.22.2-2.2-2.02.1-2.1-2.12.22.12.22.22.2-1.71.41.4-1.30.90.2
One hour access (shock baseline)1.54.07.5-1.7-2.2-2.32.4-2.42.4-1.2-2.41.1-1.11.02.0-1.51.51.5-2.6-0.8-1.5-1.7-1.72.7-2.7-2.72.2-2.5-2.1
Social response proportion3.03.97.3-2.3-2.1-2.01.9-2.01.9-2.3-2.02.3-2.32.32.2-2.32.32.3-1.7-2.3-2.3-2.7-2.60.6-0.6-0.60.60.10.8
Social responses0.10.10.5-0.3-0.3-0.30.3-0.30.3-0.2-0.40.2-0.20.20.5-0.40.40.4-0.4-0.2-0.4-0.7-0.60.2-0.3-0.30.1-0.1-0.0
Social time4.67.212.4-3.3-2.8-2.62.6-2.62.6-3.5-2.53.5-3.53.53.0-3.33.33.3-2.2-3.5-3.4-2.6-2.50.7-0.6-0.50.20.41.4
Soleus weight2.16.112.71.92.62.8-2.82.8-2.81.32.8-1.21.2-1.1-2.41.8-1.8-1.83.10.91.81.91.7-3.53.43.4-3.63.22.8
Bone: stiffness0.40.72.00.90.70.6-0.60.6-0.61.10.6-1.11.1-1.1-0.70.8-0.8-0.80.41.10.81.21.40.2-0.3-0.3-0.3-0.6-0.9
Tibialis anterior weight6.622.732.65.65.15.0-4.94.9-4.95.74.9-5.75.7-5.7-5.35.5-5.5-5.54.55.65.55.75.4-2.01.91.9-2.20.3-1.3
Time to tail flick, vehicle, before self-admin0.60.81.7-1.1-0.8-0.70.7-0.70.7-1.2-0.71.3-1.31.30.7-1.11.11.1-0.5-1.3-1.2-0.6-0.60.10.20.20.10.50.8
Time to tail flick, vehicle, after self-admin1.63.34.7-1.9-2.1-2.12.1-2.12.1-1.7-2.11.7-1.71.62.2-1.81.81.8-2.1-1.6-1.9-2.0-2.01.7-1.6-1.61.6-1.1-0.6
Time to tail flick, test, before self-admin2.73.18.71.21.81.9-1.91.9-1.90.81.9-0.70.7-0.6-1.51.4-1.4-1.42.10.51.40.90.9-2.52.52.5-2.92.42.1
Time to tail flick, test, after self-admin0.90.92.30.60.91.0-1.01.0-1.00.41.0-0.30.3-0.3-0.90.8-0.8-0.81.20.20.80.40.4-1.51.51.5-1.51.41.3
Delta time to tail flick, vehicle, before/after SA2.52.73.9-1.7-1.9-1.91.9-1.91.9-1.4-1.91.3-1.31.32.0-1.41.41.4-2.0-1.2-1.5-1.9-1.91.6-1.7-1.71.6-1.3-0.9
Delta time to tail flick, test, before/after SA0.10.10.4-0.2-0.3-0.40.4-0.40.4-0.1-0.40.1-0.10.10.3-0.20.20.2-0.4-0.1-0.2-0.2-0.20.3-0.5-0.50.6-0.4-0.4
Tibia length1.23.57.1-1.5-2.0-2.22.2-2.22.2-1.0-2.20.9-0.90.82.1-1.31.31.3-2.4-0.6-1.3-1.1-1.42.6-2.7-2.72.3-2.4-2.0
Ambulatory time before self-admin0.20.71.21.01.01.0-1.01.0-1.01.01.0-1.01.0-1.0-0.61.0-1.0-1.00.90.90.81.11.1-0.60.50.5-0.30.3-0.0
Ambulatory time after self-admin0.81.42.41.41.21.2-1.21.2-1.11.51.1-1.51.5-1.5-1.11.5-1.5-1.51.01.51.41.00.9-0.40.30.3-0.1-0.0-0.5
Bone: tissue strength1.01.12.4-1.1-0.7-0.60.5-0.50.5-1.4-0.51.5-1.51.50.7-1.31.31.3-0.3-1.6-1.4-0.8-0.7-0.40.70.7-1.01.01.4
Total heroin consumption0.50.61.20.90.90.9-0.90.9-0.90.90.9-0.90.9-0.9-1.10.9-0.9-0.90.90.90.90.50.6-0.50.60.6-0.30.30.0
Bone: trabecular number0.10.20.80.30.40.5-0.50.5-0.50.20.5-0.20.2-0.1-0.50.3-0.3-0.30.50.10.20.60.6-0.30.60.6-0.90.50.4
Bone: trabecular spacing0.40.62.1-0.6-0.8-0.90.9-0.90.9-0.4-0.90.4-0.40.40.9-0.50.50.5-1.0-0.3-0.4-0.9-1.10.7-1.0-1.01.5-0.8-0.7
Bone: trabecular thickness0.20.21.1-0.10.20.3-0.30.3-0.3-0.20.30.3-0.30.30.1-0.10.10.10.4-0.4-0.20.0-0.0-0.80.80.8-0.61.01.0
Bone: trabecular tissue density1.32.24.1-1.8-1.5-1.31.3-1.31.3-2.0-1.32.0-2.02.01.7-1.91.91.9-1.1-2.0-1.9-1.4-1.20.1-0.0-0.00.20.61.1
Water consumed over 24 hours1.12.23.11.71.71.6-1.61.6-1.61.71.6-1.61.6-1.6-1.61.8-1.8-1.81.51.61.71.21.1-1.01.01.0-1.00.60.1
Number of responses in last shaping day0.30.51.20.70.40.3-0.20.2-0.20.90.2-0.91.0-1.0-0.70.8-0.8-0.80.11.00.90.20.20.5-0.5-0.50.2-0.8-1.1