Hub : Genes

Trpc3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain intron excision ratio chr2_119485307_119496374 0.04 0.03 3.5e-03 0.02 0.02 0.01 0.01 6.7e-03 4.6e-03 8.3e-02 1.5e-02
2 Brain intron excision ratio chr2_119485307_119499985 0.13 0.07 3.6e-09 0.1 0.1 0.1 0.1 1.3e-09 1.0e-09 1.1e-09 3.1e-09
3 Brain isoform ratio NM_001415005.1 0.09 0.06 2.5e-06 0.07 0.06 0.06 0.05 4.8e-07 4.3e-06 3.4e-06 1.0e-05
4 Brain intron excision ratio chr2_119496457_119499985 0.04 0.03 2.5e-03 0.03 0.03 0.01 0.03 4.6e-04 1.6e-03 3.5e-02 1.4e-03
5 Brain isoform ratio XM_008760941.3 0.13 0.07 2.5e-09 0.1 0.09 0.09 0.09 9.0e-10 4.8e-09 2.7e-08 1.1e-08
6 Brain mRNA stability Trpc3 0.41 0.15 0.0e+00 0.31 0.34 0.34 0.34 2.4e-29 3.4e-32 1.9e-32 7.9e-33
7 pVTA isoform ratio NM_001415005.1 0.08 0.06 2.3e-03 0.05 0.05 0.03 0.04 2.8e-03 4.1e-03 2.1e-02 1.0e-02
8 BLA gene expression Trpc3 0.37 0.14 2.8e-16 0.3 0.31 0.3 0.3 9.6e-17 3.8e-17 1.6e-16 2.2e-16
9 PL mRNA stability Trpc3 0.1 0.06 7.1e-08 0.07 0.07 0.07 0.07 4.2e-08 1.2e-08 3.6e-08 5.9e-08
10 Brain gene expression Trpc3 0.27 0.12 0.0e+00 0.26 0.25 0.24 0.25 1.1e-23 3.1e-23 2.3e-22 2.5e-23
11 PL gene expression Trpc3 0.56 0.19 0.0e+00 0.26 0.27 0.27 0.27 9.3e-29 7.6e-30 9.0e-30 2.6e-29
12 pVTA mRNA stability Trpc3 0.13 0.08 6.8e-04 0.07 0.04 0.04 0.05 4.7e-04 7.3e-03 6.7e-03 4.7e-03
13 OFC mRNA stability Trpc3 0.18 0.12 8.2e-03 0.06 0.04 0.02 0.05 1.7e-02 3.4e-02 1.3e-01 3.0e-02
14 pVTA gene expression Trpc3 0.24 0.12 5.4e-07 0.15 0.14 0.14 0.14 4.8e-07 7.6e-07 1.5e-06 1.5e-06
15 NAcc mRNA stability Trpc3 0.15 0.1 7.3e-08 0.07 0.07 0.06 0.07 5.1e-09 7.5e-09 1.1e-07 8.9e-09
16 NAcc gene expression Trpc3 0.3 0.11 0.0e+00 0.3 0.3 0.3 0.31 3.1e-35 8.5e-36 9.2e-36 3.5e-36
17 OFC gene expression Trpc3 0.5 0.16 5.5e-09 0.33 0.32 0.3 0.34 1.3e-08 2.0e-08 5.9e-08 8.4e-09
18 LHb gene expression Trpc3 0.44 0.18 4.4e-07 0.3 0.3 0.29 0.31 6.5e-08 5.9e-08 1.1e-07 4.5e-08
19 IL gene expression Trpc3 0.6 0.16 5.1e-10 0.39 0.38 0.41 0.39 1.8e-10 3.8e-10 6.7e-11 1.6e-10
20 BLA alternative TSS NM_001415005.1 0.09 0.07 1.9e-03 0 0.01 0.01 0 2.1e-01 1.0e-01 1.5e-01 1.9e-01
21 BLA alternative TSS NM_001415005.1 0.09 0.07 2.4e-03 0 0.01 0 0 2.2e-01 1.1e-01 1.5e-01 1.8e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density0.30.61.3-0.20.20.00.0-0.1-0.6-0.80.7-0.7-0.70.81.00.8-0.80.80.90.80.8-1.11.01.0
Area under the delay curve0.70.82.50.7-0.7-1.0-1.00.9-0.1-1.60.5-0.6-0.70.20.80.7-0.70.70.80.80.9-0.51.41.4
BMI with tail2.27.120.24.5-4.5-4.3-4.34.53.0-2.9-2.11.91.7-2.2-1.5-1.31.3-1.3-1.3-1.6-1.11.31.51.4
BMI without tail0.81.75.42.2-2.2-2.3-2.32.31.1-2.2-0.50.40.3-0.7-0.2-0.10.1-0.1-0.0-0.10.10.01.51.5
Body weight2.711.226.45.1-5.0-5.0-5.04.94.0-2.1-3.33.22.8-3.1-2.7-2.62.6-2.6-2.5-2.7-2.22.30.30.2
Weight adjusted by age0.00.00.1-0.30.20.20.2-0.3-0.2-0.20.2-0.2-0.1-0.00.00.1-0.10.1-0.00.0-0.00.1-0.1-0.1
Bone surface0.40.61.11.0-1.0-1.0-1.00.91.0-0.2-0.90.90.9-1.0-0.5-0.80.8-0.8-0.7-0.7-0.70.6-0.3-0.3
Bone volume0.00.00.10.1-0.1-0.1-0.10.00.0-0.0-0.10.10.10.10.2-0.00.0-0.00.00.10.1-0.40.10.1
Breakpoint value in progressive ratio session1.41.52.71.6-1.6-1.6-1.61.51.5-0.3-1.31.31.1-1.4-1.2-1.01.0-1.0-1.2-1.2-1.11.1-0.3-0.3
Number of licking bursts1.51.74.12.0-1.9-1.8-1.81.71.5-0.6-1.41.41.2-1.1-1.4-1.11.1-1.1-1.2-1.2-1.00.7-0.0-0.1
Context. condit. distance diff. score2.22.75.3-1.11.20.80.8-1.0-1.7-0.81.7-1.7-1.82.01.91.9-1.91.91.82.01.9-2.31.51.5
Locomotion velocity, session 12.52.74.01.0-0.9-0.7-0.70.61.71.3-1.81.91.9-1.8-1.9-1.91.9-1.9-2.0-1.9-1.91.8-1.8-1.8
Locomotion distance, session 13.14.05.31.9-1.8-1.6-1.61.52.30.8-2.32.32.3-2.3-2.0-2.22.2-2.2-2.1-2.1-2.12.3-1.6-1.6
Locomotion velocity, session 22.83.24.91.1-1.0-0.7-0.70.61.81.5-2.02.12.1-1.8-2.1-2.12.1-2.1-2.2-2.1-2.11.7-2.0-2.0
Locomotion distance, session 22.12.94.41.1-1.1-0.8-0.80.61.71.4-2.02.01.9-1.8-2.1-2.02.0-2.0-2.1-1.9-1.91.9-1.8-1.8
Locomotion velocity, session 30.00.00.10.1-0.1-0.1-0.10.00.20.3-0.20.20.3-0.3-0.0-0.20.2-0.2-0.20.1-0.0-0.1-0.3-0.3
Locomotion distance, session 30.10.10.40.00.10.10.1-0.20.20.6-0.40.40.3-0.2-0.4-0.40.4-0.4-0.4-0.1-0.30.1-0.5-0.5
Stereotopy head waving bouts, day 31.01.22.30.2-0.20.10.1-0.00.91.4-1.11.21.3-1.1-0.8-1.31.3-1.3-1.2-1.3-1.31.2-1.5-1.5
Stereotopy head waving duration, day 30.10.20.40.5-0.5-0.5-0.50.60.5-0.1-0.40.30.5-0.60.1-0.40.4-0.4-0.2-0.4-0.30.4-0.1-0.1
Locomotion velocity, session 71.41.52.10.8-0.7-0.4-0.40.51.21.1-1.41.51.4-1.3-1.4-1.41.4-1.4-1.5-1.4-1.41.3-1.3-1.3
Locomotion distance, session 70.60.72.2-1.31.41.51.5-1.5-0.91.20.5-0.4-0.40.9-0.10.4-0.40.40.10.40.4-0.7-0.6-0.5
Stereotopy head waving bouts, day 70.70.81.41.1-1.0-0.8-0.80.81.20.3-1.11.21.0-1.0-0.5-1.01.0-1.0-0.8-0.8-1.00.9-0.6-0.7
Stereotopy head waving duration, day 70.60.71.21.0-0.9-0.8-0.80.81.10.2-1.01.00.9-1.0-0.5-0.90.9-0.9-0.8-0.8-0.90.9-0.5-0.5
Locomotion velocity, session 80.30.31.20.6-0.6-0.7-0.70.70.0-1.10.2-0.2-0.40.20.50.3-0.30.30.40.50.5-0.60.90.9
Locomotion distance, session 80.00.10.20.5-0.3-0.5-0.50.30.1-0.2-0.20.30.00.2-0.2-0.10.1-0.1-0.10.20.2-0.50.20.2
Degree of sensitization distance1.11.12.5-1.51.61.61.6-1.5-1.30.61.0-0.9-0.81.30.50.9-0.90.90.60.70.8-1.0-0.00.0
Degree of sensitization stereotypy0.30.30.90.9-0.9-0.9-0.90.80.8-0.4-0.60.60.4-0.60.0-0.50.5-0.5-0.2-0.2-0.40.40.00.0
Conditioned locomotion1.82.14.1-2.02.01.81.8-2.0-1.80.31.6-1.5-1.51.51.01.3-1.31.31.11.21.1-1.30.30.3
Cocaine response after cond. corrected2.12.44.0-1.11.00.70.7-0.7-1.5-1.01.7-1.7-1.71.62.01.7-1.71.71.81.91.9-1.81.51.5
Cocaine response after cond. not corrected0.60.71.8-0.80.70.60.6-0.5-0.8-0.30.9-0.9-0.80.81.40.9-0.90.91.01.11.0-0.90.60.6
Cocaine response before conditioning2.32.85.11.1-1.2-1.0-1.01.01.91.0-1.81.72.1-2.2-1.4-1.91.9-1.9-1.7-1.8-2.02.3-1.6-1.6
Saline control response2.43.25.81.4-1.4-1.2-1.21.22.00.9-1.91.92.1-2.3-1.5-2.02.0-2.0-1.8-1.9-2.12.4-1.6-1.6
Bone: connectivity density0.50.92.01.4-1.4-1.4-1.41.31.1-0.6-0.90.90.9-0.9-0.6-0.80.8-0.8-0.7-0.9-0.70.50.10.1
Bone: cortical apparent density0.40.51.6-1.01.21.31.3-1.3-0.61.30.2-0.1-0.10.6-0.30.1-0.10.1-0.1-0.3-0.3-0.2-0.8-0.7
Bone: cortical area0.30.51.31.1-1.1-1.2-1.21.00.9-0.5-0.60.60.7-0.7-0.2-0.50.5-0.5-0.3-0.1-0.20.30.10.1
Bone: cortical porosity1.41.55.90.7-1.0-1.4-1.41.4-0.1-2.40.9-1.1-1.0-0.11.40.9-0.90.91.20.91.0-0.02.02.0
Bone: cortical porosity1.01.03.80.4-0.7-1.0-1.01.1-0.1-2.00.8-1.0-0.9-0.11.30.8-0.80.81.20.80.80.11.61.6
Bone: cortical thickness0.20.41.0-0.1-0.0-0.4-0.40.2-0.3-0.80.6-0.7-0.60.31.00.6-0.60.60.90.80.8-0.50.90.9
Bone: cortical thickness0.30.40.60.7-0.7-0.6-0.60.60.70.0-0.70.70.7-0.6-0.8-0.70.7-0.7-0.8-0.7-0.60.5-0.3-0.3
Bone: cortical tissue density0.40.61.8-1.01.21.31.3-1.3-0.61.30.2-0.0-0.10.6-0.40.1-0.10.1-0.2-0.4-0.3-0.2-0.8-0.8
Condit. Reinf. active minus inactive responses0.60.71.31.1-1.1-0.9-0.91.11.0-0.2-0.90.90.9-0.9-0.8-0.80.8-0.8-0.7-0.6-0.60.9-0.2-0.2
Condit. Reinf. active-inactive response ratio0.20.31.00.7-0.7-0.6-0.60.90.2-1.00.1-0.1-0.10.00.10.2-0.20.20.30.40.4-0.00.80.8
Condit. Reinf. active responses2.83.45.62.4-2.3-2.1-2.12.32.3-0.2-2.01.91.9-2.0-1.7-1.91.9-1.9-1.7-1.7-1.62.0-0.6-0.6
Condit. Reinf. inactive responses5.66.69.32.7-2.7-2.4-2.42.43.10.6-2.82.82.8-3.0-2.6-2.82.8-2.8-2.7-2.9-2.62.8-1.6-1.6
Incentive salience index mean0.70.91.41.2-1.1-0.9-0.91.21.20.0-1.01.01.0-1.0-0.9-1.01.0-1.0-0.9-0.8-0.81.0-0.4-0.4
Condit. Reinf. lever presses1.52.03.01.2-1.2-1.0-1.01.11.60.7-1.61.61.7-1.6-1.4-1.61.6-1.6-1.5-1.4-1.51.7-1.1-1.2
Condit. Reinf. active minus inactive responses0.91.22.11.2-1.3-1.2-1.21.11.3-0.0-1.11.11.2-1.4-0.8-1.11.1-1.1-1.0-0.9-1.01.2-0.5-0.6
Condit. Reinf. active-inactive response ratio0.40.40.9-0.40.40.20.2-0.3-0.6-0.50.7-0.7-0.80.61.00.7-0.70.70.80.80.7-0.70.60.6
Condit. Reinf. active responses3.65.07.42.2-2.3-2.0-2.01.92.60.5-2.52.42.5-2.7-2.1-2.52.5-2.5-2.3-2.2-2.32.6-1.5-1.5
Condit. Reinf. inactive responses8.110.013.73.3-3.3-2.9-2.92.93.70.5-3.53.43.4-3.7-3.3-3.43.4-3.4-3.3-3.3-3.33.7-1.9-2.0
Condit. Reinf. lever presses0.81.13.21.7-1.7-1.8-1.81.61.2-1.2-0.80.70.8-1.0-0.5-0.60.6-0.6-0.5-0.5-0.50.70.50.4
Condit. Reinf. lever reinforcers received3.24.56.72.2-2.2-2.0-2.01.92.50.4-2.32.32.4-2.6-2.1-2.32.3-2.3-2.2-2.1-2.22.5-1.4-1.4
Conditioned reinforcement - actives0.90.92.6-1.41.51.61.6-1.5-0.91.60.5-0.4-0.30.80.40.4-0.40.40.30.40.3-0.5-0.7-0.7
Conditioned reinforcement - inactives1.01.11.8-1.31.31.21.2-1.2-1.20.51.1-1.0-1.01.20.91.1-1.11.11.10.90.9-1.00.30.3
Conditioned locomotion1.31.52.60.4-0.20.20.2-0.11.11.4-1.31.51.6-1.0-1.5-1.51.5-1.5-1.5-1.5-1.50.8-1.6-1.6
Patch foraging indifference point 0 sec0.81.34.41.9-1.9-2.1-2.12.01.0-1.9-0.50.50.2-0.40.0-0.20.2-0.20.0-0.10.00.11.21.2
Patch foraging indifference point AUC1.31.52.60.8-0.8-0.5-0.50.61.30.7-1.31.31.5-1.4-1.5-1.31.3-1.3-1.5-1.6-1.61.6-1.2-1.2
Delay disc. indifference point, 0s delay0.80.92.3-0.40.40.70.7-0.70.51.4-0.70.70.8-0.8-1.0-1.01.0-1.0-1.1-1.0-1.10.8-1.5-1.5
Delay disc. indifference point, 16s delay0.40.41.80.9-0.9-0.9-0.90.90.3-1.3-0.1-0.1-0.0-0.30.20.1-0.10.10.20.20.3-0.10.80.8
Delay disc. indifference point, 2s delay0.30.30.80.5-0.6-0.7-0.70.70.1-0.90.2-0.3-0.50.10.40.4-0.40.40.40.50.5-0.20.90.9
Delay disc. indifference point, 24s delay0.90.91.4-0.70.70.50.5-0.6-1.1-0.61.1-1.2-0.91.01.11.1-1.11.11.11.11.1-1.01.01.0
Delay disc. indifference point, 4s delay0.60.72.21.3-1.4-1.5-1.51.40.8-1.1-0.40.40.2-0.7-0.2-0.30.3-0.3-0.1-0.2-0.10.40.70.7
Delay disc. indifference point, 8s delay1.11.11.8-0.30.3-0.0-0.00.0-1.0-1.01.1-1.1-1.21.11.31.3-1.31.31.31.31.3-1.11.31.3
Indifference point function ln k1.92.74.8-0.70.60.20.2-0.2-1.5-1.41.7-1.8-2.11.92.11.7-1.71.72.02.22.1-1.72.02.0
Indifference point function log k1.92.74.8-0.70.60.20.2-0.2-1.5-1.41.7-1.8-2.11.92.11.7-1.71.72.02.22.1-1.72.02.0
Patch foraging total patch changes 0 sec0.81.24.01.8-1.8-2.0-2.01.91.0-1.9-0.50.50.3-0.4-0.0-0.20.2-0.2-0.0-0.2-0.10.31.11.1
Patch foraging total patch changes 12 sec0.00.00.20.1-0.10.00.00.10.20.1-0.20.10.3-0.1-0.3-0.10.1-0.1-0.2-0.4-0.40.3-0.1-0.1
Patch foraging total patch changes 18 sec0.60.71.61.3-1.2-1.1-1.11.11.1-0.7-0.90.90.8-0.7-0.7-0.60.6-0.6-0.7-0.8-0.70.70.0-0.0
Patch foraging total patch changes 24 sec1.92.45.92.4-2.4-2.4-2.42.31.9-1.2-1.51.51.3-1.4-1.0-1.11.1-1.1-1.0-1.1-1.01.10.20.2
Patch foraging total patch changes 6 sec0.81.13.21.6-1.7-1.8-1.81.81.2-1.3-0.80.70.7-1.0-0.4-0.50.5-0.5-0.4-0.6-0.50.90.50.5
Patch foraging time to switch 0 sec0.60.92.0-1.41.41.41.4-1.3-1.10.70.9-0.8-0.81.10.60.9-0.90.90.70.90.8-1.0-0.1-0.0
Patch foraging water rate 0 sec0.10.10.80.3-0.5-0.4-0.40.40.1-0.90.0-0.1-0.1-0.20.2-0.10.1-0.10.10.10.10.10.40.4
Patch foraging water rate 12 sec0.40.61.10.6-0.6-0.5-0.50.40.80.2-0.90.80.9-1.0-0.8-1.01.0-1.0-0.9-0.9-0.91.1-0.7-0.7
Patch foraging water rate 18 sec0.60.81.11.1-1.0-0.9-0.90.91.1-0.1-1.01.11.0-1.0-0.9-1.01.0-1.0-0.9-1.0-0.90.8-0.5-0.5
Patch foraging water rate 24 sec0.81.21.71.0-1.0-0.7-0.70.61.20.2-1.31.31.2-1.3-1.2-1.31.3-1.3-1.2-1.3-1.31.1-0.9-0.9
Patch foraging water rate 6 sec0.10.20.40.4-0.4-0.5-0.50.30.4-0.0-0.50.50.5-0.5-0.3-0.60.6-0.6-0.4-0.5-0.50.6-0.4-0.4
Seeking ratio, delayed vs. immediate footshock1.11.34.71.8-1.8-2.2-2.21.91.0-1.4-0.60.60.3-0.8-0.2-0.50.5-0.5-0.2-0.2-0.10.40.90.9
Distance traveled before self-admin0.50.61.01.0-1.0-0.8-0.80.80.9-0.5-0.80.70.7-1.0-0.8-0.80.8-0.8-0.7-0.8-0.70.6-0.2-0.2
Distance traveled after self-admin1.61.83.61.9-1.8-1.6-1.61.71.6-0.8-1.31.31.0-1.4-1.2-1.51.5-1.5-1.1-1.2-1.00.8-0.1-0.1
Extensor digitorum longus weight1.97.319.44.3-4.3-4.4-4.44.43.0-2.7-2.22.01.6-2.4-1.8-1.71.7-1.7-1.4-1.7-1.41.81.11.1
Bone: elastic displacement4.45.07.3-1.41.30.80.8-0.8-2.3-2.02.6-2.6-2.72.52.32.6-2.62.62.62.52.5-2.22.62.6
Bone: elastic work3.54.56.3-1.91.81.41.4-1.5-2.4-1.12.5-2.5-2.52.42.32.4-2.42.42.42.42.3-2.01.81.9
Bone: endosteal estimation1.32.84.42.1-2.0-1.7-1.71.72.00.1-2.02.01.9-1.7-1.7-1.81.8-1.8-1.7-1.5-1.51.3-0.9-0.9
Bone: endosteal perimeter1.22.53.81.4-1.3-1.1-1.11.01.70.7-1.81.81.9-1.8-1.8-1.81.8-1.8-1.9-1.6-1.61.5-1.4-1.4
Epididymis fat weight2.76.49.13.0-3.0-2.8-2.82.73.0-0.2-2.82.72.5-2.8-2.6-2.62.6-2.6-2.6-2.6-2.42.6-1.1-1.1
Delta time in closed arm before/after self-admin1.01.01.51.1-1.1-0.8-0.80.91.20.1-1.11.11.0-1.2-1.1-1.01.0-1.0-1.1-1.1-1.11.0-0.6-0.6
Delta time in open arm before/after self-admin0.40.30.6-0.60.50.20.2-0.3-0.70.10.7-0.6-0.70.80.80.6-0.60.60.70.80.7-0.30.50.5
Diff in mean of infusions in LGA sessions0.50.52.01.0-0.9-1.1-1.11.10.3-1.40.0-0.1-0.3-0.00.30.4-0.40.40.40.30.4-0.41.11.1
Delay discount exponential model param0.91.02.9-0.60.61.01.0-0.90.31.7-0.70.80.9-0.4-1.0-0.90.9-0.9-1.0-1.0-1.10.7-1.6-1.6
Extinction: sum of active levers before priming0.80.81.10.7-0.6-0.5-0.50.51.00.7-1.01.10.9-0.9-1.0-0.90.9-0.9-1.0-1.0-1.00.9-0.8-0.8
Active lever presses in extinction session 60.00.00.10.3-0.3-0.4-0.40.40.2-0.2-0.10.1-0.1-0.00.00.1-0.10.10.00.00.1-0.10.20.2
Bone: final force1.52.35.32.2-2.2-2.3-2.32.21.8-1.0-1.41.31.3-1.7-1.0-1.31.3-1.3-1.0-1.2-1.11.50.10.1
Bone: final moment1.21.94.92.1-2.1-2.2-2.22.11.6-1.2-1.21.11.0-1.5-0.8-1.01.0-1.0-0.8-0.9-0.81.20.30.3
Food consumed during 24 hour testing period0.10.10.30.6-0.4-0.4-0.40.40.3-0.2-0.30.30.20.1-0.3-0.20.2-0.2-0.2-0.4-0.2-0.00.20.2
Glucose0.10.20.6-0.60.60.80.8-0.7-0.30.60.2-0.1-0.10.20.1-0.10.1-0.1-0.10.2-0.10.2-0.4-0.4
Heart weight0.60.82.71.2-1.4-1.6-1.61.60.8-1.5-0.30.10.1-0.70.1-0.30.3-0.3-0.0-0.0-0.00.70.90.8
Delay discount hyperbolic model param0.80.92.5-0.60.60.90.9-0.90.31.6-0.60.70.8-0.4-0.9-0.90.9-0.9-1.0-0.9-1.00.6-1.5-1.5
Intermittent access intake day 1-15 change1.31.34.2-1.91.81.91.9-2.0-1.31.00.8-0.8-0.80.80.50.6-0.60.60.40.50.3-0.5-0.6-0.6
Intermittent access intake escalation1.61.53.7-1.91.91.81.8-1.9-1.60.61.2-1.1-1.01.30.91.0-1.01.00.90.90.8-0.8-0.1-0.1
Intermittent access intake escalation 20.40.41.0-1.01.00.90.9-1.0-0.80.30.6-0.5-0.40.60.40.4-0.40.40.40.40.3-0.5-0.1-0.1
Intermitt. access day 1 inactive lever presses0.00.00.2-0.30.30.40.4-0.4-0.20.20.1-0.10.10.0-0.2-0.10.1-0.1-0.1-0.2-0.10.1-0.2-0.2
Intermitt. access day 15 inactive lever presses0.40.40.9-1.00.80.70.7-0.8-0.9-0.10.7-0.9-0.70.40.60.7-0.70.70.50.60.40.10.20.2
Intermitt. access escalation Index0.00.00.20.2-0.2-0.3-0.30.40.3-0.1-0.20.30.00.1-0.1-0.10.1-0.1-0.1-0.1-0.10.3-0.1-0.1
Intermittent access day 1 total infusions1.01.16.3-0.91.01.31.3-1.40.02.5-0.50.60.8-0.2-0.6-0.70.7-0.7-0.9-0.6-0.80.5-1.7-1.7
Intermittent access day 15 total infusions1.31.45.9-1.81.91.91.9-2.1-0.82.40.3-0.1-0.00.60.00.1-0.10.1-0.10.0-0.2-0.1-1.4-1.4
Intermittent access terminal intake (last 3 days)1.81.97.6-1.91.92.22.2-2.4-0.72.8-0.00.10.40.1-0.4-0.40.4-0.4-0.6-0.4-0.70.2-2.0-2.0
Intermittent access total infusions1.71.98.1-0.70.81.11.1-1.20.52.8-1.01.11.2-0.7-1.2-1.21.2-1.2-1.5-1.2-1.41.1-2.2-2.2
Intermittent access day 1 locomotion0.70.71.60.3-0.20.10.1-0.10.81.0-0.91.01.3-0.7-1.0-1.01.0-1.0-1.0-1.0-0.90.4-1.1-1.1
Intermittent access day 15 total locomotion0.20.20.9-0.10.40.40.4-0.50.11.0-0.30.50.30.2-0.3-0.40.4-0.4-0.3-0.3-0.3-0.3-0.7-0.7
Intermittent access total locomotion1.21.32.20.6-0.3-0.0-0.00.01.11.3-1.21.41.4-0.9-1.3-1.51.5-1.5-1.4-1.3-1.30.8-1.4-1.4
Intermittent access standard deviation0.70.81.3-1.00.90.60.6-0.8-1.1-0.21.0-1.1-1.10.91.01.0-1.01.00.91.00.9-0.60.60.6
Left kidney weight0.00.10.10.4-0.3-0.4-0.40.20.2-0.1-0.30.30.4-0.1-0.4-0.30.3-0.3-0.3-0.2-0.20.1-0.1-0.1
Right kidney weight0.20.51.51.2-1.1-1.2-1.21.10.7-0.4-0.70.70.5-0.4-0.6-0.50.5-0.5-0.5-0.4-0.30.30.20.2
Cocaine induced anxiety1.01.11.91.4-1.3-1.1-1.11.21.3-0.3-1.11.11.1-1.2-1.1-1.11.1-1.1-1.1-1.1-1.00.7-0.4-0.4
Post-drug Anxiety1.61.83.01.7-1.7-1.6-1.61.51.6-0.7-1.41.31.3-1.5-1.3-1.31.3-1.3-1.3-1.3-1.21.2-0.3-0.3
Baseline Anxiety0.70.71.1-0.30.3-0.1-0.1-0.0-0.8-1.00.9-0.9-1.00.91.01.0-1.01.01.01.01.0-0.61.01.0
Tail length0.00.10.30.5-0.4-0.6-0.60.40.2-0.3-0.30.30.1-0.2-0.2-0.20.2-0.2-0.1-0.2-0.0-0.10.10.0
Length with tail0.51.94.62.0-1.9-2.2-2.21.91.6-0.6-1.51.61.2-1.2-1.1-1.31.3-1.3-1.0-1.1-0.90.9-0.2-0.2
Length without tail1.53.46.52.6-2.4-2.5-2.52.32.2-0.6-2.02.01.7-1.6-1.8-1.71.7-1.7-1.6-1.7-1.51.5-0.3-0.3
Times rat made contact with spout0.10.10.4-0.20.40.50.5-0.5-0.10.6-0.20.30.30.3-0.4-0.10.1-0.1-0.3-0.3-0.2-0.3-0.4-0.4
Lifetime Intake1.71.98.3-0.60.71.01.0-1.10.52.9-1.01.11.3-0.8-1.2-1.21.2-1.2-1.5-1.2-1.51.2-2.2-2.2
Liver weight, left0.10.20.90.2-0.10.10.1-0.10.30.7-0.50.60.4-0.1-0.9-0.50.5-0.5-0.7-0.5-0.50.1-0.6-0.6
Liver weight, right0.00.00.2-0.30.40.40.4-0.4-0.30.10.1-0.1-0.10.20.00.0-0.00.00.00.00.1-0.2-0.1-0.1
Locomotor activity0.00.10.3-0.0-0.2-0.3-0.30.30.0-0.50.2-0.3-0.0-0.30.4-0.00.0-0.00.20.20.10.50.30.3
Locomotor testing distance1.93.16.62.4-2.6-2.5-2.52.52.1-1.2-1.51.31.5-2.1-1.2-1.51.5-1.5-1.2-1.2-1.22.10.10.1
Locomotor testing rearing0.10.20.50.4-0.6-0.7-0.70.50.3-0.6-0.0-0.10.1-0.60.2-0.10.1-0.10.10.20.00.60.40.4
Locomotion in novel chamber1.51.83.81.9-1.9-1.7-1.71.81.6-0.7-1.31.31.2-1.3-1.3-1.31.3-1.3-1.1-1.3-1.10.9-0.1-0.1
Locomotion in novel chamber post-restriction0.00.00.40.1-0.2-0.2-0.20.20.0-0.60.1-0.2-0.1-0.20.20.0-0.00.00.20.00.10.10.30.3
Fecal boli incidents, locomotor time 11.31.42.7-1.71.61.41.4-1.5-1.40.31.2-1.2-1.31.40.91.1-1.11.10.81.20.9-0.80.10.2
Change in fecal boli incidents, locomotor task2.12.02.91.4-1.4-1.0-1.01.01.70.5-1.61.61.5-1.6-1.5-1.71.7-1.7-1.6-1.6-1.51.4-1.0-1.0
Time >=10cm from walls, locomotor time 10.70.71.30.2-0.20.20.2-0.10.60.8-0.80.81.2-0.8-0.9-1.01.0-1.0-0.9-1.0-1.00.9-1.0-1.0
Bouts of movement, locomotor time 11.11.21.9-1.41.41.31.3-1.1-1.30.31.1-1.0-1.11.31.11.2-1.21.21.11.01.0-1.00.30.3
Total resting periods, locomotor time 12.22.43.5-1.81.91.61.6-1.5-1.80.31.6-1.5-1.71.91.61.7-1.71.71.61.61.5-1.50.60.6
Rest time, locomotor task time 11.31.42.9-1.61.61.51.5-1.7-1.40.61.2-1.1-0.81.31.11.1-1.11.11.01.11.0-1.20.10.1
Distance moved, locomotor task time 12.22.43.82.0-1.9-1.6-1.61.72.00.1-1.71.71.3-1.7-1.6-1.71.7-1.7-1.5-1.5-1.51.4-0.6-0.6
Vertical activity count, locomotor time 11.81.94.22.1-2.0-1.8-1.82.01.7-0.7-1.41.31.0-1.3-1.3-1.31.3-1.3-1.1-1.3-1.11.10.10.0
Time >=10cm from walls, locomotor time 20.30.30.8-0.70.70.90.9-0.8-0.20.9-0.00.00.20.1-0.2-0.20.2-0.2-0.3-0.1-0.20.2-0.7-0.7
Bouts of movement, locomotor time 23.23.45.3-2.32.32.02.0-2.0-2.2-0.02.0-2.0-1.72.01.91.9-1.91.91.92.01.8-1.70.70.7
Total resting periods, locomotor time 22.52.73.8-1.91.91.61.6-1.7-1.9-0.41.8-1.8-1.51.81.81.8-1.81.81.81.91.7-1.50.80.8
Rest time, locomotor task time 20.40.50.8-0.50.50.30.3-0.3-0.7-0.60.8-0.7-0.50.80.80.9-0.90.90.90.70.8-0.70.70.7
Distance moved, locomotor task time 21.61.92.91.4-1.3-0.9-0.91.01.70.5-1.61.51.3-1.6-1.6-1.71.7-1.7-1.5-1.5-1.51.3-1.0-1.0
Vertical activity count, locomotor time 22.93.25.31.3-1.2-0.7-0.70.81.91.1-2.01.91.9-1.9-2.1-2.32.3-2.3-2.2-2.0-2.11.8-1.7-1.7
Light reinforcement 10.10.10.5-0.70.60.50.5-0.6-0.40.50.3-0.3-0.20.30.20.2-0.20.20.20.20.00.2-0.3-0.2
Light reinforcement 20.10.20.6-0.70.70.60.6-0.8-0.40.70.2-0.1-0.10.50.10.1-0.10.10.10.1-0.0-0.1-0.4-0.3
Bone: marrow area1.32.74.52.1-2.0-1.7-1.71.72.00.0-2.02.01.9-1.7-1.7-1.81.8-1.8-1.7-1.5-1.41.2-0.8-0.8
Bone: maximum diameter0.61.11.61.2-1.2-1.1-1.11.01.20.0-1.21.21.3-1.0-1.1-1.11.1-1.1-1.1-0.8-0.80.9-0.5-0.6
Bone: maximum force0.40.71.91.2-1.3-1.4-1.41.21.0-0.7-0.70.70.7-0.9-0.4-0.60.6-0.6-0.4-0.5-0.50.70.20.1
Bone: maximum moment0.30.51.71.2-1.2-1.3-1.31.20.8-0.9-0.50.40.4-0.6-0.3-0.40.4-0.4-0.2-0.3-0.30.50.40.4
Mean time between licks in bursts0.00.00.00.1-0.1-0.1-0.10.10.00.0-0.10.1-0.20.0-0.2-0.00.0-0.0-0.1-0.1-0.0-0.2-0.0-0.0
Mean num. licks in bursts1.31.53.4-1.81.81.81.8-1.7-1.40.61.3-1.3-1.01.21.31.1-1.11.11.11.00.9-0.80.00.1
Cd content in liver0.40.41.6-1.00.91.01.0-1.0-0.31.30.00.00.2-0.1-0.2-0.20.2-0.2-0.4-0.1-0.40.5-1.0-1.0
Co content in liver0.30.30.50.6-0.7-0.7-0.70.60.6-0.1-0.60.50.5-0.6-0.7-0.60.6-0.6-0.6-0.6-0.70.5-0.2-0.2
Cu content in liver0.30.30.70.7-0.7-0.6-0.60.60.6-0.0-0.70.70.5-0.5-0.9-0.60.6-0.6-0.7-0.6-0.60.4-0.2-0.3
Fe content in liver0.50.61.2-0.40.2-0.0-0.0-0.1-0.6-0.90.9-0.9-0.90.51.10.9-0.90.91.01.00.9-0.40.90.9
K content in liver0.30.30.8-0.80.80.90.9-0.8-0.60.50.4-0.4-0.40.60.50.4-0.40.40.40.40.3-0.5-0.1-0.1
Mg content in liver0.80.81.3-1.11.11.11.1-1.1-1.10.20.9-0.8-0.91.10.80.9-0.90.90.80.80.8-1.00.20.3
Mn content in liver2.12.43.6-1.81.81.81.8-1.6-1.70.31.6-1.5-1.51.61.91.6-1.61.61.61.41.4-1.70.50.5
Na content in liver1.31.41.81.3-1.2-1.1-1.11.01.30.3-1.31.41.3-1.3-1.3-1.21.2-1.2-1.2-1.3-1.21.1-0.8-0.8
Rb content in liver0.30.41.80.6-0.7-0.9-0.90.90.1-1.30.3-0.4-0.4-0.10.30.2-0.20.20.40.30.20.31.01.0
Se content in liver1.01.35.1-1.11.11.31.3-1.30.12.3-0.50.60.8-0.6-0.3-0.80.8-0.8-0.7-0.7-1.00.8-2.0-2.0
Sr content in liver1.00.91.50.4-0.4-0.3-0.30.30.91.1-1.11.11.1-1.0-1.1-1.21.2-1.2-1.2-0.8-1.01.1-1.2-1.2
Zn content in liver1.01.12.0-0.80.90.70.7-0.8-1.2-0.51.1-1.1-1.21.40.81.2-1.21.21.01.21.2-1.30.90.9
Bone: minimum diameter0.71.33.01.7-1.7-1.7-1.71.61.4-0.6-1.21.21.3-1.2-0.7-1.11.1-1.1-0.8-0.5-0.60.8-0.1-0.1
Time in familiar zone, hab. session 10.20.20.7-0.20.20.40.4-0.40.20.8-0.40.40.5-0.2-0.5-0.50.5-0.5-0.6-0.3-0.50.4-0.8-0.8
Time in novel zone, hab. session 10.10.10.20.3-0.4-0.5-0.50.40.3-0.3-0.10.10.0-0.5-0.1-0.20.2-0.2-0.1-0.3-0.20.50.10.1
Total zone transitions, hab. session 10.91.34.21.7-1.9-2.1-2.11.91.1-1.5-0.60.50.4-1.0-0.4-0.50.5-0.5-0.3-0.2-0.20.90.80.8
Total locomotion distance, hab. session 11.11.53.31.6-1.8-1.7-1.71.81.5-0.8-1.11.00.9-1.5-0.9-1.01.0-1.0-0.8-0.9-0.91.5-0.0-0.0
Locomotion velocity, hab. session 10.91.33.61.6-1.8-1.8-1.81.91.3-1.1-0.80.70.7-1.3-0.6-0.70.7-0.7-0.5-0.7-0.61.20.40.4
Time in familiar zone, hab. session 21.31.43.7-1.91.81.71.7-1.8-1.40.81.2-1.2-0.80.91.01.0-1.01.00.90.80.6-0.7-0.2-0.2
Time in novel zone, hab. session 21.11.13.11.8-1.7-1.7-1.71.71.2-1.1-0.90.90.6-0.8-0.7-0.70.7-0.7-0.6-0.6-0.40.60.40.4
Total zone transitions, hab. session 22.83.65.42.3-2.3-2.2-2.22.12.2-0.2-2.01.91.9-2.2-1.9-1.91.9-1.9-1.8-1.8-1.71.9-0.7-0.7
Total locomotion distance, hab. session 21.92.53.81.9-2.0-1.7-1.71.81.9-0.2-1.61.61.6-1.9-1.6-1.61.6-1.6-1.5-1.5-1.51.9-0.6-0.6
Locomotion velocity, hab. session 22.63.55.02.1-2.1-1.8-1.81.92.20.0-2.01.91.9-2.2-2.0-1.91.9-1.9-1.9-1.9-1.92.2-0.9-0.9
Novel to familiar place preference ratio2.22.34.5-0.20.1-0.2-0.20.3-1.1-2.01.5-1.6-1.81.32.01.6-1.61.61.91.61.8-1.42.12.1
Novelty place preference2.82.85.4-0.30.2-0.2-0.20.2-1.3-2.21.7-1.8-2.01.42.21.8-1.81.82.11.92.0-1.62.32.3
Time in novel zone, NPP test2.82.96.1-0.0-0.1-0.5-0.50.5-1.1-2.51.6-1.7-2.01.32.21.8-1.81.82.11.92.0-1.52.52.5
Total zone transitions, NPP test2.33.35.61.2-1.2-1.0-1.00.81.81.3-2.02.02.0-2.0-2.4-2.02.0-2.0-2.1-2.1-2.12.2-1.8-1.8
Total locomotion distance, NPP test1.92.64.31.0-1.0-0.7-0.70.71.71.2-1.71.71.8-1.8-2.1-1.81.8-1.8-1.9-1.9-1.92.1-1.7-1.7
Locomotion velocity, NPP test1.72.54.30.7-0.7-0.5-0.50.51.51.4-1.61.61.7-1.7-2.1-1.71.7-1.7-1.9-1.9-1.92.1-1.8-1.8
Intraocular pressure0.20.30.7-0.80.70.80.8-0.6-0.60.20.5-0.5-0.30.40.40.6-0.60.60.30.40.3-0.2-0.1-0.0
Delta distance traveled before/after self-admin0.10.10.30.5-0.4-0.5-0.50.50.3-0.3-0.20.30.0-0.0-0.1-0.30.3-0.3-0.1-0.10.0-0.00.20.2
Delta ambulatory time before/after self-admin0.10.10.20.4-0.3-0.4-0.40.40.3-0.3-0.20.30.1-0.1-0.2-0.30.3-0.3-0.2-0.1-0.10.10.00.0
Parametrial fat weight0.40.82.20.8-0.7-0.5-0.50.40.90.4-1.11.11.0-0.8-1.5-1.01.0-1.0-1.2-1.1-1.00.6-0.7-0.7
Pavlov. Cond. lever latency1.21.52.6-0.90.80.50.5-0.6-1.2-1.01.4-1.5-1.41.21.61.4-1.41.41.51.31.3-1.21.31.3
Pavlov. Cond. magazine entry latency1.01.32.41.5-1.4-1.3-1.31.31.3-0.1-1.31.31.2-1.0-1.6-1.11.1-1.1-1.2-1.0-0.90.9-0.4-0.4
Pavlov. Cond. change in total contacts0.91.01.80.9-0.8-0.5-0.50.71.10.7-1.21.21.2-1.0-1.3-1.21.2-1.2-1.2-1.0-1.01.2-0.9-0.9
Pavlov. Cond. index score2.83.56.01.8-1.6-1.3-1.31.32.10.9-2.22.32.2-1.9-2.5-2.12.1-2.1-2.2-2.0-1.91.8-1.5-1.6
Pavlov. Cond. latency score2.63.35.61.6-1.4-1.1-1.11.11.91.1-2.12.22.1-1.8-2.4-2.12.1-2.1-2.2-1.9-1.91.8-1.6-1.7
Pavlov. Cond. lever contacts2.12.44.21.2-1.0-0.6-0.60.71.61.2-1.81.91.9-1.5-2.0-1.81.8-1.8-1.9-1.6-1.61.6-1.6-1.6
Pavlov. Cond. magazine entry number2.02.54.5-2.01.81.61.6-1.6-1.8-0.11.9-1.9-1.71.42.11.7-1.71.71.81.51.4-1.20.80.8
Pavlov. Cond. intertrial magazine entries0.40.51.0-1.01.00.90.9-0.7-0.80.10.8-0.8-0.70.81.00.7-0.70.70.80.70.6-0.50.20.2
Pavlov. Cond. lever-magazine prob. diff.2.53.15.31.8-1.6-1.3-1.31.32.00.8-2.12.12.0-1.8-2.3-2.02.0-2.0-2.1-1.8-1.81.7-1.4-1.4
Pavlov. Cond. response bias2.02.44.51.8-1.6-1.3-1.31.31.80.5-1.91.91.7-1.4-2.1-1.71.7-1.7-1.8-1.5-1.41.3-1.0-1.0
Pavlov. Cond. lever latency2.53.36.8-2.62.62.52.5-2.4-2.11.11.8-1.7-1.71.91.41.6-1.61.61.41.61.4-1.70.00.1
Pavlov. Cond. magazine entry latency0.70.83.00.8-0.8-1.0-1.00.8-0.2-1.70.4-0.4-0.60.50.70.7-0.70.70.80.60.8-1.01.51.5
Pavlov. Cond. change in total contacts3.14.28.52.9-2.9-2.9-2.92.72.4-1.2-2.01.81.9-2.3-1.6-1.81.8-1.8-1.6-1.9-1.72.0-0.1-0.1
Pavlov. Cond. index score2.43.17.82.8-2.8-2.8-2.82.62.0-1.7-1.51.51.3-1.6-1.1-1.21.2-1.2-1.0-1.3-1.01.10.50.5
Pavlov. Cond. latency score2.02.46.22.5-2.4-2.4-2.42.31.8-1.4-1.41.31.2-1.4-1.0-1.11.1-1.1-0.9-1.2-0.91.00.40.4
Pavlov. Cond. lever contacts3.04.17.92.8-2.8-2.7-2.72.62.4-1.0-2.01.91.9-2.2-1.6-1.81.8-1.8-1.6-1.8-1.71.9-0.2-0.2
Pavlov. Cond. magazine entry number1.31.65.3-2.12.12.32.3-2.1-1.12.10.6-0.5-0.40.60.20.3-0.30.30.10.3-0.0-0.1-1.3-1.3
Pavlov. Cond. intertrial magazine entries0.30.40.80.3-0.3-0.1-0.10.20.60.7-0.70.70.8-0.7-0.8-0.70.7-0.7-0.9-0.6-0.70.8-0.8-0.8
Pavlov. Cond. lever-magazine prob. diff.2.43.17.32.7-2.7-2.7-2.72.52.0-1.4-1.61.61.4-1.7-1.2-1.31.3-1.3-1.2-1.4-1.11.20.30.3
Pavlov. Cond. response bias2.33.17.92.7-2.7-2.8-2.82.62.0-1.7-1.51.41.3-1.8-1.0-1.21.2-1.2-1.0-1.2-1.01.40.50.5
Time in closed arm before self-admin0.80.91.5-1.21.21.21.2-1.1-1.2-0.01.0-1.0-0.81.00.90.9-0.90.90.91.00.9-0.80.30.3
Time in closed arm after self-admin0.30.30.7-0.40.40.80.8-0.60.10.8-0.30.30.4-0.3-0.5-0.30.3-0.3-0.5-0.4-0.50.3-0.9-0.8
Time in open arm before self-admin1.71.95.12.3-2.2-2.1-2.12.21.6-1.3-1.11.10.7-1.2-0.9-1.01.0-1.0-0.7-1.0-0.70.40.60.5
Time in open arm after self-admin0.30.31.50.8-0.9-1.2-1.21.10.3-0.7-0.10.1-0.1-0.10.1-0.00.0-0.00.10.00.20.10.70.7
Bone: periosteal estimation0.81.73.31.8-1.7-1.6-1.61.51.6-0.2-1.51.51.5-1.3-1.0-1.31.3-1.3-1.1-0.9-0.90.8-0.4-0.4
Bone: periosteal perimeter0.71.11.91.0-1.0-0.9-0.90.91.30.3-1.21.21.4-1.4-1.0-1.21.2-1.2-1.1-0.9-1.01.2-0.8-0.8
Bone: post-yield work0.40.50.90.5-0.4-0.2-0.20.10.70.7-0.91.00.9-0.6-0.9-0.80.8-0.8-0.8-0.8-0.80.5-0.9-0.9
Progressive ratio test 1 active lever presses2.32.43.80.8-0.7-0.3-0.30.31.61.6-1.71.72.0-1.5-1.8-1.81.8-1.8-1.8-1.8-1.81.7-1.7-1.7
Progressive ratio test 1 breakpoint2.52.64.10.7-0.7-0.2-0.20.21.61.7-1.71.82.0-1.6-1.9-1.91.9-1.9-1.9-1.9-1.91.7-1.9-1.9
Progressive ratio test 1 inactive lever presses1.31.43.40.00.10.40.4-0.40.91.8-1.11.21.2-0.9-1.3-1.31.3-1.3-1.4-1.3-1.41.2-1.7-1.7
Progressive ratio test 2 active lever presses1.61.77.4-0.70.81.11.1-1.20.42.7-0.91.11.2-0.6-1.2-1.11.1-1.1-1.3-1.2-1.30.8-2.1-2.1
Progressive ratio test 2 breakpoint1.92.17.3-0.40.50.90.9-1.00.82.7-1.21.31.4-1.0-1.5-1.51.5-1.5-1.6-1.5-1.61.1-2.2-2.2
Progressive ratio test 2 inactive lever presses0.70.84.0-1.21.21.41.4-1.4-0.42.0-0.00.10.30.2-0.3-0.20.2-0.2-0.4-0.3-0.40.2-1.2-1.2
Incentive Sensitization - Responses0.90.94.0-0.60.81.11.1-1.10.12.0-0.60.70.8-0.4-0.8-0.70.7-0.7-0.9-0.8-0.90.3-1.6-1.6
Incentive Sensitization - Breakpoint1.01.04.4-0.70.81.11.1-1.20.12.1-0.60.70.8-0.4-0.9-0.80.8-0.8-0.9-0.9-0.90.3-1.7-1.6
Sum of active levers in priming session hrs 5-60.90.81.70.1-0.10.20.2-0.10.70.9-0.90.91.0-1.0-1.0-0.90.9-0.9-1.2-1.1-1.21.2-1.3-1.3
Progressive ratio0.20.20.6-0.20.30.50.5-0.40.20.8-0.30.30.5-0.3-0.4-0.40.4-0.4-0.4-0.4-0.40.3-0.7-0.7
Food seeking constrained by brief footshock1.11.44.81.9-1.9-2.2-2.22.21.1-1.4-0.60.50.1-0.8-0.2-0.30.3-0.3-0.2-0.1-0.00.51.01.0
Seeking ratio, punishment vs. effort0.70.92.71.3-1.3-1.6-1.61.60.4-1.6-0.0-0.0-0.3-0.10.20.3-0.30.30.30.40.5-0.01.21.2
Retroperitoneal fat weight1.55.06.92.4-2.4-2.0-2.01.92.60.1-2.52.52.5-2.4-2.5-2.42.4-2.4-2.4-2.6-2.32.2-1.3-1.3
Reaction time number correct1.82.65.5-0.10.10.60.6-0.61.12.3-1.51.51.8-1.4-1.6-1.81.8-1.8-1.9-1.8-2.01.9-2.3-2.3
Reaction time mean minus median1.92.510.81.3-1.4-1.9-1.91.7-0.1-3.30.8-1.0-1.20.31.11.1-1.11.11.31.31.4-1.12.62.5
Reaction time mean minus median AUC1.21.66.41.1-1.2-1.7-1.71.5-0.0-2.50.6-0.7-0.90.10.80.8-0.80.81.01.01.1-0.92.01.9
Reaction time num false alarms0.00.00.20.0-0.1-0.1-0.10.2-0.0-0.30.1-0.20.1-0.20.40.1-0.10.10.30.10.1-0.00.20.2
Reaction time num false alarms AUC0.00.00.1-0.0-0.00.00.0-0.00.10.2-0.10.00.3-0.40.1-0.20.2-0.2-0.1-0.1-0.20.2-0.2-0.2
Reaction time trials correct on left1.82.65.5-0.10.10.60.6-0.61.12.3-1.51.51.8-1.4-1.6-1.81.8-1.8-1.9-1.8-2.01.9-2.3-2.3
Reaction time trials on left1.72.45.0-0.10.10.60.6-0.61.02.2-1.41.41.8-1.3-1.6-1.71.7-1.7-1.8-1.7-1.91.8-2.2-2.2
Reaction time mean1.72.37.00.9-1.0-1.6-1.61.5-0.4-2.61.0-1.2-1.50.51.51.3-1.31.31.61.51.6-1.32.42.4
Reaction time mean AUC2.02.77.60.7-0.9-1.5-1.51.4-0.6-2.81.2-1.4-1.70.71.71.6-1.61.61.81.71.8-1.52.62.6
Median of all reaction times1.41.94.30.4-0.5-1.0-1.01.0-0.6-2.01.1-1.2-1.60.71.51.4-1.41.41.61.51.6-1.32.12.1
Reaction time omissions3.95.311.1-0.1-0.0-0.6-0.60.7-1.6-3.32.2-2.4-2.61.92.52.6-2.62.62.72.62.8-2.43.33.3
Reaction time false alarm rate0.20.20.70.3-0.3-0.5-0.50.5-0.1-0.90.3-0.4-0.30.00.60.4-0.40.40.60.40.4-0.40.80.8
Reaction time premature initiation rate3.24.27.1-2.72.62.22.2-2.2-2.60.62.3-2.1-2.12.42.12.0-2.02.02.02.22.0-1.90.70.7
Reaction time premature initiations1.41.95.4-2.32.32.22.2-2.2-1.61.71.1-1.0-0.71.30.90.7-0.70.70.70.80.6-0.6-0.7-0.7
Std. dev. reaction times2.02.912.01.6-1.7-2.2-2.22.10.1-3.50.7-0.9-1.20.21.21.1-1.11.11.31.31.4-1.22.72.6
Reaction time trials completed1.72.45.0-0.10.10.60.6-0.61.02.2-1.41.41.8-1.3-1.6-1.71.7-1.7-1.8-1.7-1.91.8-2.2-2.2
Reaction time trials AUC1.62.44.8-0.10.10.60.6-0.51.02.2-1.41.41.8-1.3-1.6-1.71.7-1.7-1.8-1.7-1.91.8-2.2-2.2
Run reversals in cocaine runway, females0.60.60.90.8-0.7-0.5-0.50.70.90.1-0.80.80.7-0.9-0.8-1.01.0-1.0-0.8-0.8-0.80.8-0.5-0.5
Run reversals in cocaine runway, males0.90.81.51.1-1.1-0.9-0.90.91.1-0.1-1.01.01.0-1.0-0.9-1.01.0-1.0-0.9-1.2-1.00.8-0.4-0.4
Latency to leave start box in cocaine runway1.41.52.8-0.20.2-0.2-0.20.3-1.1-1.41.3-1.2-1.41.41.21.4-1.41.41.51.41.6-1.51.71.7
Latency to leave start box in cocaine runway, F1.51.62.8-0.80.90.40.4-0.6-1.3-0.61.4-1.2-1.61.61.51.4-1.41.41.61.51.6-1.71.21.2
Latency to leave start box in cocaine runway, M0.60.61.3-0.20.1-0.1-0.10.3-0.7-1.00.8-0.9-0.70.80.60.9-0.90.90.80.80.9-0.71.21.2
Std. dev. time between licks in bursts0.30.30.90.9-0.9-0.9-0.90.90.4-0.9-0.20.2-0.1-0.1-0.6-0.10.1-0.1-0.2-0.2-0.0-0.10.60.6
Total sessions with >9 infusions0.00.00.2-0.10.20.20.2-0.20.00.5-0.10.10.00.1-0.1-0.00.0-0.0-0.0-0.1-0.10.0-0.2-0.2
Short access day 1 total inactive lever presses1.11.22.50.4-0.30.00.00.11.01.6-1.21.31.3-0.9-1.3-1.21.2-1.2-1.3-1.3-1.31.0-1.4-1.4
Short access day 10 total inactive lever presses0.00.00.00.0-0.00.00.0-0.00.0-0.1-0.00.00.1-0.1-0.2-0.00.0-0.0-0.1-0.2-0.10.1-0.0-0.0
Short access day 1 total infusions0.50.51.10.1-0.10.10.1-0.00.61.1-0.70.70.8-0.7-0.8-0.70.7-0.7-0.8-0.8-0.80.7-0.9-0.9
Short access day 10 total infusions0.50.62.10.1-0.10.10.1-0.20.61.5-0.70.70.8-0.6-0.7-0.80.8-0.8-0.9-0.7-0.91.0-1.0-1.0
Short access total infusions1.11.25.0-0.30.30.60.6-0.70.62.2-0.90.91.1-0.8-1.1-1.01.0-1.0-1.2-1.1-1.21.1-1.7-1.7
Short access day 1 locomotion0.40.51.41.2-1.0-1.0-1.01.10.9-0.6-0.60.70.5-0.4-0.5-0.50.5-0.5-0.4-0.5-0.30.20.20.2
Short access day 10 total locomotion0.10.20.80.5-0.4-0.4-0.40.50.1-0.90.1-0.2-0.10.20.30.0-0.00.00.20.30.3-0.20.70.7
Short access total locomotion0.20.20.50.2-0.10.10.1-0.10.50.4-0.50.60.7-0.4-0.5-0.70.7-0.7-0.6-0.5-0.50.3-0.6-0.6
One hour access (0.3 mA shock)2.22.67.50.00.10.50.5-0.61.12.7-1.51.71.7-1.1-1.8-1.81.8-1.8-1.9-1.8-1.91.3-2.4-2.4
Compulsive drug intake3.53.56.32.5-2.4-2.2-2.22.22.3-0.1-2.02.12.0-2.0-2.0-1.81.8-1.8-1.7-2.0-1.71.4-0.5-0.6
One hour access (shock baseline)1.31.55.5-1.92.02.02.0-2.2-0.92.30.3-0.1-0.00.6-0.0-0.10.1-0.1-0.2-0.0-0.3-0.0-1.6-1.5
Social response proportion3.13.37.2-2.72.62.42.4-2.7-2.40.41.9-1.8-1.51.81.61.6-1.61.61.51.61.4-1.50.10.1
Social responses0.10.10.3-0.40.40.50.5-0.5-0.30.2-0.00.00.2-0.1-0.2-0.10.1-0.1-0.1-0.2-0.20.3-0.4-0.4
Social time3.85.18.7-3.02.82.42.4-2.5-2.80.02.6-2.6-2.42.32.42.2-2.22.22.32.42.1-1.80.90.9
Soleus weight0.92.69.81.0-1.1-1.5-1.51.4-0.5-3.11.1-1.2-1.41.01.11.4-1.41.41.51.11.5-1.52.82.7
Bone: stiffness0.71.11.81.3-1.3-1.2-1.21.21.3-0.0-1.11.11.2-1.3-0.6-1.11.1-1.1-0.9-0.9-0.91.1-0.5-0.5
Tibialis anterior weight3.913.228.35.3-5.3-5.1-5.15.14.3-2.0-3.63.43.0-3.7-3.1-3.13.1-3.1-2.8-3.1-2.83.00.0-0.0
Time to tail flick, vehicle, before self-admin1.21.22.4-0.30.2-0.2-0.20.3-1.0-1.41.2-1.3-1.31.11.41.0-1.01.01.41.41.4-1.11.61.6
Time to tail flick, vehicle, after self-admin0.91.03.4-1.51.51.81.8-1.8-0.71.50.3-0.3-0.00.30.10.2-0.20.2-0.10.1-0.1-0.1-1.1-1.1
Time to tail flick, test, before self-admin1.31.22.5-0.10.0-0.3-0.30.3-0.8-1.51.1-1.1-1.21.11.31.3-1.31.31.41.21.4-1.21.61.6
Time to tail flick, test, after self-admin1.11.22.2-0.20.1-0.2-0.20.2-0.9-1.41.1-1.2-1.31.01.31.1-1.11.11.31.31.4-1.01.51.5
Delta time to tail flick, vehicle, before/after SA1.81.86.5-1.92.02.32.3-2.4-0.82.60.1-0.00.30.3-0.20.1-0.10.1-0.4-0.2-0.50.2-1.8-1.8
Delta time to tail flick, test, before/after SA0.00.00.2-0.30.20.20.2-0.3-0.10.40.0-0.0-0.0-0.0-0.0-0.20.2-0.2-0.10.0-0.10.1-0.2-0.2
Tibia length1.13.111.7-1.21.41.81.8-1.90.23.4-1.11.31.3-0.5-1.7-1.41.4-1.4-1.7-1.3-1.61.1-2.9-2.9
Ambulatory time before self-admin0.70.71.10.8-0.8-0.5-0.50.51.00.1-1.01.01.0-1.0-1.0-1.01.0-1.0-1.0-1.0-0.90.7-0.7-0.7
Ambulatory time after self-admin1.11.22.01.2-1.1-0.9-0.90.91.30.0-1.21.21.0-1.1-1.2-1.41.4-1.4-1.2-1.2-1.00.8-0.6-0.6
Bone: tissue strength1.91.83.8-0.60.50.10.1-0.1-1.2-1.41.5-1.6-1.61.01.91.5-1.51.51.91.61.5-0.91.61.7
Total heroin consumption0.10.20.50.6-0.6-0.7-0.70.70.3-0.7-0.10.0-0.0-0.20.10.0-0.00.00.10.00.10.10.50.5
Bone: trabecular number0.10.20.60.1-0.2-0.3-0.30.2-0.2-0.80.4-0.4-0.40.20.60.4-0.40.40.50.40.4-0.40.70.7
Bone: trabecular spacing0.40.52.1-0.60.71.01.0-0.9-0.01.4-0.30.40.40.1-0.6-0.40.4-0.4-0.6-0.5-0.50.2-1.1-1.1
Bone: trabecular thickness0.60.72.3-0.80.90.90.9-0.9-1.00.20.8-0.6-0.81.20.60.8-0.80.80.70.70.7-1.50.40.4
Bone: trabecular tissue density1.92.64.1-2.02.01.91.9-1.9-2.00.11.8-1.8-1.61.91.31.7-1.71.71.41.41.3-1.60.70.7
Water consumed over 24 hours0.10.10.20.5-0.3-0.3-0.30.30.0-0.4-0.10.10.00.3-0.00.1-0.10.10.10.10.2-0.40.40.4
Number of responses in last shaping day0.20.20.30.5-0.4-0.3-0.30.40.50.3-0.50.50.4-0.4-0.4-0.50.5-0.5-0.5-0.4-0.40.2-0.3-0.3