Hub : Genes

Cdc42ep2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL mRNA stability Cdc42ep2 0.05 0.03 1.4e-04 0.04 0.04 0.03 0.04 1.5e-05 9.0e-05 9.2e-04 6.4e-05
2 OFC alternative TSS XM_063264396.1 0.13 0.08 8.5e-03 0.05 0.05 0.05 0.12 2.3e-02 2.1e-02 3.0e-02 9.2e-04
3 NAcc mRNA stability Cdc42ep2 0.04 0.02 1.8e-06 0.01 0.04 0.03 0.03 2.2e-03 1.5e-06 2.1e-05 1.2e-05
4 LHb mRNA stability Cdc42ep2 0.17 0.1 2.7e-03 0.08 0.12 0.12 0.11 5.5e-03 7.0e-04 8.6e-04 1.4e-03
5 LHb gene expression Cdc42ep2 0.14 0.1 8.0e-03 0.1 0.08 0.1 0.1 2.8e-03 6.0e-03 2.1e-03 2.3e-03
6 Adipose gene expression Cdc42ep2 0.06 0.04 1.5e-03 0.02 0.02 0.02 0.02 1.9e-03 1.8e-03 4.5e-03 2.3e-03
7 Adipose mRNA stability Cdc42ep2 0.04 0.02 2.0e-03 0.01 0.01 0.02 0.01 1.9e-02 7.7e-03 5.2e-03 9.0e-03
8 pVTA gene expression Cdc42ep2 0.03 0.02 6.7e-03 0.02 0.02 0.02 0.02 7.7e-03 1.0e-02 1.2e-02 1.7e-02
9 NAcc gene expression Cdc42ep2 0.04 0.02 1.1e-04 0.02 0.03 0.03 0.03 1.2e-04 3.4e-05 9.5e-05 8.5e-05
10 Brain gene expression Cdc42ep2 0.05 0.03 1.5e-04 0.04 0.03 0.03 0.01 1.0e-04 1.5e-03 4.4e-04 6.9e-02
11 Adipose intron excision ratio chr1_212632764_212634091 0.22 0.11 1.8e-03 0.03 0.02 0.02 0.02 7.3e-04 3.6e-03 2.8e-03 6.3e-03
12 Brain mRNA stability Cdc42ep2 0.07 0.05 2.4e-04 0.03 0.04 0.01 0.03 4.8e-04 1.2e-04 2.4e-02 2.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.71.13.80.90.70.0-0.01.01.9-1.20.31.90.8-0.4-1.3
Area under the delay curve0.30.31.3-0.20.2-0.6-0.70.30.3-0.40.80.40.40.7-1.2
BMI with tail1.86.322.12.52.00.20.22.04.7-2.01.94.41.6-0.5-3.0
BMI without tail0.61.85.21.41.70.20.00.42.3-0.71.12.00.90.8-1.8
Body weight1.14.913.73.73.62.42.4-0.33.60.2-0.72.5-1.1-0.0-0.3
Weight adjusted by age1.01.52.71.41.51.61.6-1.00.71.3-1.40.2-1.6-0.81.0
Bone surface2.44.412.63.22.22.22.30.23.6-0.1-1.52.8-0.7-2.1-0.1
Bone volume1.32.48.81.81.01.01.10.93.0-0.8-0.62.70.4-2.0-0.8
Breakpoint value in progressive ratio session1.72.14.72.21.71.81.8-1.11.61.1-1.51.0-1.1-1.00.4
Number of licking bursts0.10.20.40.60.40.60.6-0.10.60.3-0.10.4-0.4-0.50.1
Context. condit. distance diff. score1.21.53.0-1.7-1.2-1.7-1.70.9-0.9-1.21.2-0.41.10.9-1.0
Locomotion velocity, session 10.30.31.1-0.00.60.20.1-0.6-0.70.2-0.3-0.8-0.71.00.6
Locomotion distance, session 10.40.51.20.71.10.0-0.10.41.1-0.60.70.90.20.7-0.9
Locomotion velocity, session 21.11.23.71.81.91.21.2-0.21.70.1-0.51.1-0.60.0-0.1
Locomotion distance, session 20.40.51.91.01.40.30.20.01.0-0.20.70.70.00.8-0.7
Locomotion velocity, session 30.91.13.0-0.3-0.2-1.0-1.01.60.7-1.71.20.90.70.7-1.1
Locomotion distance, session 30.00.00.1-0.0-0.1-0.2-0.20.2-0.1-0.30.3-0.1-0.10.3-0.1
Stereotopy head waving bouts, day 31.41.73.9-0.9-0.4-1.4-1.41.80.3-1.92.00.61.01.1-1.3
Stereotopy head waving duration, day 30.91.12.1-1.0-0.8-1.2-1.21.40.2-1.41.30.51.10.3-1.0
Locomotion velocity, session 72.02.24.4-0.7-0.6-1.4-1.42.11.1-1.81.91.41.80.2-2.0
Locomotion distance, session 70.40.51.4-0.00.3-0.7-0.70.90.3-0.80.90.30.51.2-1.0
Stereotopy head waving bouts, day 70.60.61.6-0.2-0.5-0.4-0.31.01.0-0.70.51.20.9-1.1-0.9
Stereotopy head waving duration, day 70.60.72.60.80.50.50.50.21.60.0-0.21.50.4-1.3-0.7
Locomotion velocity, session 81.01.22.71.11.61.11.1-1.1-0.30.6-0.8-0.8-1.61.11.2
Locomotion distance, session 80.71.12.5-0.6-0.3-1.1-1.11.40.6-1.61.40.81.00.4-1.2
Degree of sensitization distance0.50.51.2-0.00.2-0.5-0.51.10.7-1.00.90.70.70.6-0.9
Degree of sensitization stereotypy0.60.62.40.70.10.50.50.21.40.0-0.41.40.4-1.5-0.5
Conditioned locomotion0.91.02.11.41.41.31.3-0.80.70.7-1.00.2-1.30.10.7
Cocaine response after cond. corrected0.91.12.2-1.5-0.8-1.4-1.40.7-1.1-1.00.9-0.80.51.5-0.4
Cocaine response after cond. not corrected0.70.81.5-1.2-0.7-1.2-1.20.8-0.9-0.90.9-0.60.51.2-0.3
Cocaine response before conditioning0.50.61.31.10.50.91.0-0.40.90.6-0.50.7-0.1-1.10.3
Saline control response2.12.97.02.52.62.22.2-1.51.01.4-1.10.1-1.80.51.2
Bone: connectivity density1.21.86.12.21.61.11.20.32.5-0.4-0.72.0-0.1-0.7-0.7
Bone: cortical apparent density0.40.51.80.30.30.60.5-1.3-0.51.3-0.6-0.7-0.60.10.4
Bone: cortical area0.40.71.31.10.91.11.10.11.00.0-0.90.7-0.7-0.90.6
Bone: cortical porosity0.10.10.40.30.40.20.2-0.00.6-0.10.00.50.2-0.1-0.4
Bone: cortical porosity0.20.20.70.70.80.50.5-0.20.80.0-0.30.6-0.1-0.0-0.2
Bone: cortical thickness2.74.56.62.22.52.62.5-2.5-0.22.4-2.5-1.1-2.50.52.1
Bone: cortical thickness1.41.62.80.71.20.90.9-1.7-1.11.4-1.2-1.5-1.61.51.2
Bone: cortical tissue density0.50.72.40.50.50.80.7-1.5-0.51.5-0.7-0.8-0.80.10.6
Condit. Reinf. active minus inactive responses0.10.10.30.30.50.10.00.00.40.10.40.30.30.3-0.5
Condit. Reinf. active-inactive response ratio0.10.10.3-0.00.20.10.0-0.4-0.10.6-0.2-0.20.30.1-0.2
Condit. Reinf. active responses0.30.40.70.10.0-0.3-0.30.70.8-0.70.70.90.7-0.1-0.9
Condit. Reinf. inactive responses0.81.02.6-0.1-0.6-0.8-0.71.51.1-1.61.21.30.9-0.4-1.0
Incentive salience index mean0.30.41.10.50.6-0.0-0.10.51.0-0.50.70.90.60.2-0.9
Condit. Reinf. lever presses0.50.62.40.90.40.30.30.71.6-0.80.31.40.4-0.6-0.6
Condit. Reinf. active minus inactive responses0.30.41.2-0.1-0.8-0.2-0.10.70.6-0.50.50.70.7-1.1-0.3
Condit. Reinf. active-inactive response ratio1.51.74.0-0.8-1.6-0.9-0.82.00.9-1.71.21.41.4-1.6-0.8
Condit. Reinf. active responses0.20.20.70.6-0.10.20.2-0.10.80.10.20.80.4-0.8-0.5
Condit. Reinf. inactive responses0.40.51.51.01.10.60.4-1.20.21.0-0.3-0.0-0.40.6-0.3
Condit. Reinf. lever presses1.21.63.61.80.81.51.6-0.21.90.5-1.01.5-0.6-1.70.3
Condit. Reinf. lever reinforcers received0.30.40.90.90.20.60.6-0.40.90.5-0.10.70.1-1.0-0.2
Conditioned reinforcement - actives0.50.86.7-0.1-0.60.50.70.50.70.0-0.50.7-0.2-2.60.8
Conditioned reinforcement - inactives1.31.96.6-1.9-2.6-1.5-1.31.2-0.6-0.90.60.21.2-2.1-0.3
Conditioned locomotion3.44.413.0-3.3-3.6-2.6-2.41.7-1.8-1.31.8-0.71.8-1.2-0.5
Patch foraging indifference point 0 sec0.00.10.20.2-0.1-0.2-0.20.30.1-0.2-0.20.20.50.0-0.3
Patch foraging indifference point AUC1.82.64.82.01.32.02.1-1.71.11.7-2.20.5-1.2-1.51.1
Delay disc. indifference point, 0s delay0.91.02.2-1.00.0-1.1-1.20.90.3-1.11.20.51.11.1-1.5
Delay disc. indifference point, 16s delay0.70.81.5-0.7-1.1-1.1-1.10.90.1-0.81.20.50.9-0.4-1.2
Delay disc. indifference point, 2s delay0.40.41.0-0.5-0.3-0.6-0.61.00.4-0.90.70.60.5-0.1-0.7
Delay disc. indifference point, 24s delay0.30.30.8-0.20.2-0.1-0.2-0.6-0.90.4-0.1-0.9-0.80.90.2
Delay disc. indifference point, 4s delay0.50.52.0-0.40.3-0.7-0.80.3-0.1-0.51.1-0.00.21.4-0.9
Delay disc. indifference point, 8s delay0.20.21.4-0.20.4-0.4-0.5-0.1-0.2-0.20.5-0.10.11.2-0.7
Indifference point function ln k4.27.413.0-3.6-2.7-3.6-3.62.5-2.5-2.83.1-1.51.82.4-1.4
Indifference point function log k4.27.413.0-3.6-2.7-3.6-3.62.5-2.5-2.83.1-1.51.82.4-1.4
Patch foraging total patch changes 0 sec0.00.10.20.20.20.0-0.0-0.2-0.40.2-0.5-0.4-0.10.50.2
Patch foraging total patch changes 12 sec2.53.38.22.92.32.22.2-1.81.71.8-2.00.9-1.3-0.60.5
Patch foraging total patch changes 18 sec0.30.51.21.10.70.70.7-0.21.10.3-0.60.90.0-0.8-0.1
Patch foraging total patch changes 24 sec1.32.23.91.91.71.92.0-1.50.41.7-1.7-0.2-1.4-0.31.4
Patch foraging total patch changes 6 sec0.50.82.81.71.51.00.9-0.60.70.5-1.10.3-0.40.50.2
Patch foraging time to switch 0 sec1.12.28.81.71.10.60.60.83.0-0.60.42.70.8-1.2-1.5
Patch foraging water rate 0 sec1.53.110.4-2.8-2.4-1.6-1.50.4-3.2-0.60.3-2.6-0.00.91.1
Patch foraging water rate 12 sec3.36.820.7-4.0-2.7-2.6-2.60.7-4.5-1.21.3-3.70.02.40.9
Patch foraging water rate 18 sec1.62.55.7-2.4-1.3-1.7-1.80.8-2.4-1.11.1-1.90.31.90.2
Patch foraging water rate 24 sec2.23.07.8-2.8-2.1-1.8-1.80.9-2.8-1.30.9-2.20.21.40.6
Patch foraging water rate 6 sec2.74.012.1-2.7-1.9-1.8-1.80.5-3.5-1.11.0-2.9-0.52.40.9
Seeking ratio, delayed vs. immediate footshock0.40.51.7-0.1-0.4-0.8-0.80.50.3-0.31.30.50.70.3-1.3
Distance traveled before self-admin0.60.82.60.90.50.60.60.31.6-0.2-0.41.50.5-1.5-0.5
Distance traveled after self-admin0.30.30.90.60.30.60.6-0.80.30.7-1.00.20.4-0.70.1
Extensor digitorum longus weight3.614.033.55.85.64.94.8-2.83.82.7-3.12.0-3.1-0.31.5
Bone: elastic displacement1.31.55.4-1.1-0.4-0.4-0.4-0.9-2.30.4-0.1-2.2-0.91.71.2
Bone: elastic work1.31.72.71.01.61.11.1-1.6-0.71.1-1.0-1.3-1.71.61.3
Bone: endosteal estimation2.04.511.5-1.1-1.4-2.0-1.83.41.5-3.42.32.12.1-0.5-2.0
Bone: endosteal perimeter2.65.513.9-1.4-1.9-2.1-1.93.71.8-3.52.22.52.5-1.5-2.1
Epididymis fat weight2.27.515.1-3.6-3.9-3.1-2.93.5-0.7-3.52.60.52.8-1.4-1.3
Delta time in closed arm before/after self-admin0.90.85.00.31.20.20.1-0.8-0.70.3-0.1-1.0-1.02.20.4
Delta time in open arm before/after self-admin0.70.74.20.5-0.20.70.8-0.20.80.4-0.80.70.4-2.10.3
Diff in mean of infusions in LGA sessions0.50.61.20.90.80.90.9-0.80.10.9-1.1-0.2-0.60.10.7
Delay discount exponential model param0.20.20.90.1-0.30.40.5-0.1-0.20.2-0.7-0.3-0.2-0.70.9
Extinction: sum of active levers before priming1.21.33.51.81.61.11.1-0.31.90.6-0.61.4-0.3-0.6-0.5
Active lever presses in extinction session 62.22.24.21.81.41.92.0-0.51.70.7-1.71.1-1.1-1.71.0
Bone: final force1.21.95.02.21.91.71.8-0.21.90.2-1.21.2-1.2-0.80.5
Bone: final moment1.11.84.52.11.81.71.7-0.21.80.2-1.11.1-1.2-0.70.5
Food consumed during 24 hour testing period0.40.51.10.1-0.20.70.8-0.6-0.30.9-1.0-0.5-0.7-0.91.0
Glucose3.04.77.7-2.1-1.8-2.7-2.72.60.2-2.82.51.12.50.6-2.4
Heart weight2.43.77.6-1.4-0.5-2.3-2.32.30.5-2.82.41.01.91.8-2.3
Delay discount hyperbolic model param0.20.21.00.2-0.20.40.5-0.3-0.30.4-0.7-0.4-0.3-0.61.0
Intermittent access intake day 1-15 change0.40.83.2-1.3-1.8-0.8-0.60.7-0.6-0.30.3-0.10.7-1.60.2
Intermittent access intake escalation0.40.83.2-1.2-1.7-0.6-0.40.6-0.5-0.20.1-0.10.6-1.80.4
Intermittent access intake escalation 20.60.72.8-1.1-1.6-0.5-0.40.5-0.4-0.10.0-0.10.7-1.70.3
Intermitt. access day 1 inactive lever presses0.10.20.8-0.4-0.5-0.2-0.2-0.8-0.40.9-0.2-0.20.3-0.3-0.1
Intermitt. access day 15 inactive lever presses0.81.74.1-1.5-2.0-1.5-1.31.20.1-1.11.10.71.6-1.6-0.9
Intermitt. access escalation Index2.02.85.0-2.2-1.7-2.2-2.21.7-1.1-1.91.7-0.41.60.9-1.4
Intermittent access day 1 total infusions3.86.111.5-2.1-2.2-2.6-2.53.41.2-3.32.52.12.9-1.2-2.5
Intermittent access day 15 total infusions3.75.511.5-2.9-3.4-2.6-2.43.0-0.0-2.51.91.12.6-2.3-1.3
Intermittent access terminal intake (last 3 days)4.66.011.8-2.6-3.2-2.5-2.33.40.6-3.01.91.62.8-2.5-1.5
Intermittent access total infusions4.75.511.2-2.3-2.7-2.5-2.33.30.8-3.12.01.82.7-1.8-1.8
Intermittent access day 1 locomotion2.83.65.6-1.8-1.9-2.1-2.02.40.7-2.32.11.42.3-0.9-1.9
Intermittent access day 15 total locomotion2.85.110.4-2.4-3.2-2.3-2.12.80.4-2.31.81.52.5-2.8-1.5
Intermittent access total locomotion7.69.115.9-2.9-3.7-3.1-2.94.00.9-3.62.72.23.5-2.9-2.4
Intermittent access standard deviation0.40.82.7-1.6-1.6-1.0-0.90.3-0.8-0.30.2-0.30.8-0.90.2
Left kidney weight0.73.15.9-1.9-1.7-2.0-1.92.40.3-2.41.41.02.4-0.5-1.6
Right kidney weight0.20.81.8-1.3-1.3-1.0-0.91.2-0.3-1.20.60.10.9-0.5-0.2
Cocaine induced anxiety0.10.21.10.2-0.00.20.3-0.10.50.3-0.30.50.4-1.1-0.0
Post-drug Anxiety0.50.51.41.20.70.91.0-0.30.80.6-0.60.5-0.6-0.70.4
Baseline Anxiety0.60.71.90.80.90.70.6-0.8-0.40.8-0.5-0.7-1.41.30.7
Tail length0.72.95.51.01.91.81.7-2.3-0.92.1-1.8-1.5-1.91.11.8
Length with tail1.56.312.02.93.53.23.1-2.70.52.4-2.7-0.7-3.00.92.3
Length without tail1.75.39.72.83.12.82.8-2.30.21.8-2.3-0.9-3.11.02.3
Times rat made contact with spout0.40.41.30.61.00.60.5-1.20.00.9-0.5-0.2-0.60.6-0.1
Lifetime Intake3.44.18.4-2.0-2.2-2.2-2.12.90.7-2.81.81.52.3-1.2-1.6
Liver weight, left0.50.91.8-1.4-0.9-1.1-1.10.9-1.0-1.20.9-0.70.31.00.0
Liver weight, right1.42.54.5-2.1-1.2-2.0-2.01.1-1.7-1.51.9-1.20.52.0-0.3
Locomotor activity1.32.16.7-1.8-1.2-1.3-1.3-0.1-2.6-0.40.4-2.2-0.51.90.7
Locomotor testing distance1.62.99.5-2.1-1.3-1.5-1.5-0.3-3.1-0.50.4-2.7-0.52.40.9
Locomotor testing rearing1.22.37.1-2.1-1.1-1.5-1.6-0.4-2.7-0.40.4-2.20.02.10.3
Locomotion in novel chamber3.24.08.5-2.8-2.9-2.4-2.32.5-0.9-2.22.10.02.0-0.7-0.9
Locomotion in novel chamber post-restriction1.62.65.7-2.3-2.4-2.0-1.91.8-0.7-1.61.40.11.7-0.8-0.9
Fecal boli incidents, locomotor time 10.40.53.00.1-0.50.20.30.51.0-0.1-0.41.00.5-1.7-0.1
Change in fecal boli incidents, locomotor task0.40.42.70.10.5-0.4-0.50.2-0.3-0.50.8-0.3-0.21.6-0.3
Time >=10cm from walls, locomotor time 13.33.57.7-0.7-1.4-1.3-1.22.81.8-2.41.72.42.2-1.8-1.8
Bouts of movement, locomotor time 12.02.36.71.41.01.81.7-2.40.22.6-1.8-0.3-1.0-0.90.8
Total resting periods, locomotor time 11.31.44.31.20.61.41.4-1.80.42.1-1.30.0-0.6-1.20.5
Rest time, locomotor task time 10.60.72.2-1.4-1.5-1.0-0.90.7-0.8-0.70.4-0.30.8-0.40.1
Distance moved, locomotor task time 10.30.41.00.30.4-0.2-0.30.80.9-0.70.60.90.50.2-1.0
Vertical activity count, locomotor time 10.30.71.3-1.0-1.0-1.1-1.10.8-0.7-0.80.8-0.30.50.4-0.5
Time >=10cm from walls, locomotor time 20.30.42.70.1-0.20.30.40.20.90.1-0.20.90.5-1.6-0.3
Bouts of movement, locomotor time 20.30.51.70.80.60.80.7-1.30.31.2-0.40.1-0.7-0.3-0.0
Total resting periods, locomotor time 20.10.20.90.50.30.40.3-0.90.40.8-0.10.3-0.2-0.4-0.3
Rest time, locomotor task time 21.41.83.5-1.9-1.7-1.7-1.71.4-0.5-1.71.30.11.40.2-0.8
Distance moved, locomotor task time 20.91.12.01.21.21.41.3-1.20.21.4-1.2-0.3-1.1-0.20.8
Vertical activity count, locomotor time 20.81.13.0-0.00.30.50.5-1.0-1.51.0-0.9-1.7-1.20.91.4
Light reinforcement 10.10.20.6-0.4-0.1-0.0-0.0-0.5-0.80.4-0.5-0.7-0.20.20.4
Light reinforcement 20.60.93.2-1.0-1.4-0.6-0.51.40.2-1.00.60.60.6-1.8-0.1
Bone: marrow area2.24.812.0-1.2-1.4-2.1-2.03.51.5-3.52.52.12.2-0.4-2.1
Bone: maximum diameter0.40.82.90.5-0.10.60.71.11.3-0.8-0.41.2-0.1-1.70.4
Bone: maximum force1.73.09.92.62.01.71.80.63.1-0.4-0.72.5-0.5-1.5-0.3
Bone: maximum moment1.62.79.02.51.91.61.70.53.0-0.5-0.62.4-0.5-1.3-0.3
Mean time between licks in bursts0.41.03.20.61.30.50.5-1.0-0.80.7-0.1-1.2-1.21.80.8
Mean num. licks in bursts0.20.20.7-0.5-0.1-0.5-0.6-0.4-0.80.10.0-0.60.30.8-0.3
Cd content in liver0.91.03.3-1.1-1.8-1.0-0.91.1-0.0-0.70.30.51.2-1.5-0.6
Co content in liver1.71.97.1-1.4-0.7-0.5-0.6-1.4-2.71.1-0.1-2.5-0.51.70.9
Cu content in liver0.20.21.0-0.1-0.2-0.4-0.5-0.10.30.00.50.50.7-0.0-1.0
Fe content in liver0.20.20.80.40.30.50.6-0.0-0.1-0.0-0.4-0.3-0.90.10.9
K content in liver0.40.41.10.71.10.10.10.50.8-0.70.40.70.10.8-0.5
Mg content in liver0.70.71.6-0.6-0.1-0.9-1.00.8-0.2-1.01.10.00.81.2-0.9
Mn content in liver1.71.94.52.11.41.92.0-0.61.50.8-1.00.9-1.1-1.20.9
Na content in liver0.60.71.60.60.81.01.0-0.8-0.10.6-1.3-0.4-0.90.21.2
Rb content in liver1.31.63.1-1.6-1.1-1.7-1.80.9-1.2-1.10.9-0.71.21.3-0.9
Se content in liver0.40.41.6-0.4-1.0-0.3-0.21.00.3-0.70.30.50.4-1.3-0.2
Sr content in liver2.52.13.91.61.52.02.0-1.60.41.6-1.7-0.2-1.5-0.81.5
Zn content in liver0.10.20.60.50.80.40.3-0.50.20.5-0.50.10.10.1-0.3
Bone: minimum diameter2.44.38.8-1.1-1.2-2.0-1.93.01.5-2.92.22.22.5-0.5-2.5
Time in familiar zone, hab. session 10.60.61.5-0.5-0.5-0.8-0.81.00.3-1.01.20.50.90.1-0.9
Time in novel zone, hab. session 10.70.72.1-0.40.10.00.0-0.7-1.40.4-0.6-1.4-0.91.10.9
Total zone transitions, hab. session 10.30.41.01.00.90.70.6-0.60.90.6-0.40.6-0.1-0.2-0.3
Total locomotion distance, hab. session 10.60.91.4-0.6-0.5-1.0-1.01.20.6-1.21.10.81.20.0-1.2
Locomotion velocity, hab. session 10.30.40.9-0.1-0.1-0.5-0.50.60.7-0.70.60.80.8-0.1-1.0
Time in familiar zone, hab. session 20.60.72.60.10.50.00.0-0.5-1.10.1-0.2-1.3-1.01.60.8
Time in novel zone, hab. session 20.30.30.90.2-0.00.0-0.00.20.90.00.20.90.7-0.8-0.8
Total zone transitions, hab. session 21.01.24.21.31.50.30.30.32.1-0.50.81.80.60.2-1.4
Total locomotion distance, hab. session 21.11.43.0-0.10.3-0.9-1.01.31.2-1.51.71.31.20.6-1.7
Locomotion velocity, hab. session 21.31.83.6-0.3-0.0-1.1-1.11.61.3-1.71.91.61.50.2-1.9
Novel to familiar place preference ratio1.01.13.81.10.31.01.0-0.21.70.6-0.41.50.1-2.0-0.2
Novelty place preference0.60.73.00.70.00.60.7-0.11.30.4-0.31.30.3-1.7-0.3
Time in novel zone, NPP test0.50.52.10.60.00.50.6-0.11.10.3-0.21.10.3-1.5-0.3
Total zone transitions, NPP test1.01.43.81.91.91.31.3-0.51.90.4-0.71.3-0.3-0.3-0.3
Total locomotion distance, NPP test0.30.51.20.20.4-0.3-0.40.60.9-0.80.80.90.70.4-1.1
Locomotion velocity, NPP test0.30.41.10.30.4-0.2-0.30.41.0-0.50.61.00.70.1-1.1
Intraocular pressure0.60.83.4-1.2-1.9-0.4-0.2-0.2-0.80.4-0.5-0.50.2-1.60.7
Delta distance traveled before/after self-admin0.70.82.3-0.30.0-0.0-0.1-1.1-1.50.8-0.4-1.5-0.31.50.7
Delta ambulatory time before/after self-admin0.70.82.2-0.10.30.10.1-1.2-1.40.9-0.5-1.5-0.61.50.8
Parametrial fat weight3.06.910.7-3.0-3.2-3.2-3.13.3-0.1-3.12.81.13.1-0.7-2.3
Pavlov. Cond. lever latency0.20.20.8-0.5-0.5-0.2-0.2-0.2-0.90.3-0.3-0.8-0.20.10.5
Pavlov. Cond. magazine entry latency0.60.72.30.50.30.0-0.00.51.5-0.40.71.50.9-0.7-1.2
Pavlov. Cond. change in total contacts0.70.72.20.3-0.30.00.00.51.3-0.20.41.50.9-1.5-1.0
Pavlov. Cond. index score0.20.20.70.50.20.40.4-0.10.80.10.00.80.2-0.7-0.3
Pavlov. Cond. latency score0.20.20.70.30.20.10.10.20.8-0.20.40.80.4-0.4-0.6
Pavlov. Cond. lever contacts0.20.20.60.30.3-0.1-0.10.40.8-0.60.50.80.40.1-0.6
Pavlov. Cond. magazine entry number0.30.41.2-0.6-0.2-0.7-0.70.5-0.7-0.70.5-0.60.01.10.0
Pavlov. Cond. intertrial magazine entries0.20.31.1-0.8-1.0-0.4-0.4-0.0-0.70.10.1-0.50.3-0.60.2
Pavlov. Cond. lever-magazine prob. diff.0.30.41.30.70.40.50.4-0.01.10.10.01.00.3-0.8-0.5
Pavlov. Cond. response bias0.20.20.70.50.20.50.5-0.30.70.4-0.30.60.1-0.8-0.1
Pavlov. Cond. lever latency0.50.71.8-0.9-0.3-0.9-1.1-0.2-1.1-0.10.9-0.90.51.3-0.5
Pavlov. Cond. magazine entry latency2.12.65.92.42.02.01.9-1.12.11.2-1.61.5-0.9-1.0-0.0
Pavlov. Cond. change in total contacts1.21.95.81.70.51.41.4-0.12.30.6-1.02.0-0.0-2.4-0.3
Pavlov. Cond. index score1.41.94.81.91.11.61.6-0.32.20.6-1.21.7-0.5-1.70.0
Pavlov. Cond. latency score1.31.74.61.71.01.41.5-0.02.10.4-1.11.7-0.3-1.7-0.0
Pavlov. Cond. lever contacts0.50.71.80.90.31.01.10.11.10.2-1.00.9-0.4-1.30.4
Pavlov. Cond. magazine entry number3.84.710.2-3.2-2.4-2.8-2.81.5-2.6-1.92.1-1.71.31.7-0.4
Pavlov. Cond. intertrial magazine entries0.50.71.3-1.1-1.1-1.1-1.00.9-0.7-0.90.7-0.30.70.0-0.2
Pavlov. Cond. lever-magazine prob. diff.1.72.35.12.11.31.81.8-0.42.30.8-1.41.7-0.6-1.80.1
Pavlov. Cond. response bias1.21.63.41.81.11.61.6-0.41.80.6-1.31.4-0.6-1.50.2
Time in closed arm before self-admin0.60.81.8-0.5-1.1-0.6-0.51.20.7-0.80.71.00.9-1.4-0.7
Time in closed arm after self-admin0.30.30.8-0.4-0.3-0.8-0.80.6-0.3-0.60.9-0.20.10.9-0.4
Time in open arm before self-admin1.51.69.7-0.60.7-0.5-0.7-0.9-1.90.50.3-1.9-0.53.10.1
Time in open arm after self-admin0.30.31.00.10.50.50.4-1.0-0.60.7-0.6-0.7-0.10.60.5
Bone: periosteal estimation0.81.64.90.1-0.4-0.5-0.32.21.7-2.10.81.80.9-1.1-0.8
Bone: periosteal perimeter0.61.02.60.40.0-0.00.11.51.6-1.40.41.60.5-1.1-0.6
Bone: post-yield work5.58.122.70.9-0.2-0.9-0.83.44.5-3.02.34.82.9-2.4-3.6
Progressive ratio test 1 active lever presses0.40.51.3-0.8-0.9-0.5-0.40.80.3-0.8-0.10.60.7-1.2-0.3
Progressive ratio test 1 breakpoint0.40.41.6-0.7-0.9-0.4-0.30.70.4-0.7-0.10.60.6-1.3-0.2
Progressive ratio test 1 inactive lever presses0.10.20.8-0.4-0.5-0.1-0.1-0.40.00.5-0.60.10.2-0.9-0.1
Progressive ratio test 2 active lever presses2.02.45.4-1.9-2.3-1.6-1.41.90.2-1.61.00.91.6-2.0-0.7
Progressive ratio test 2 breakpoint2.02.35.4-1.9-2.3-1.5-1.31.80.1-1.50.90.81.5-2.0-0.6
Progressive ratio test 2 inactive lever presses4.06.415.0-3.3-3.9-3.0-2.82.9-0.6-2.42.30.72.7-2.1-1.6
Incentive Sensitization - Responses0.50.71.6-0.1-0.5-0.4-0.31.31.1-1.10.61.20.8-1.1-0.7
Incentive Sensitization - Breakpoint0.60.81.8-0.3-0.7-0.6-0.51.30.9-1.10.71.20.9-1.1-0.7
Sum of active levers in priming session hrs 5-62.92.77.31.20.11.92.2-1.00.41.6-2.0-0.0-1.7-2.72.2
Progressive ratio1.21.97.01.10.90.20.11.22.6-1.10.72.50.9-0.9-1.7
Food seeking constrained by brief footshock0.10.10.60.40.30.10.1-0.1-0.20.20.2-0.3-0.70.80.2
Seeking ratio, punishment vs. effort1.42.17.8-1.3-0.8-0.7-0.8-0.9-2.80.60.1-2.6-0.72.01.1
Retroperitoneal fat weight5.423.146.4-6.8-6.1-6.4-6.34.8-3.3-5.25.0-1.14.21.1-2.6
Reaction time number correct0.30.61.50.40.70.90.9-0.5-0.30.5-1.2-0.6-1.20.11.2
Reaction time mean minus median1.12.85.82.41.52.12.1-1.02.31.5-0.81.7-0.6-2.10.3
Reaction time mean minus median AUC0.71.73.21.71.01.71.8-1.21.31.5-0.90.8-0.9-1.40.8
Reaction time num false alarms0.71.05.3-0.70.1-0.7-0.8-0.3-1.5-0.00.5-1.5-0.12.30.1
Reaction time num false alarms AUC0.50.84.60.00.7-0.1-0.3-0.8-1.10.50.2-1.2-0.52.10.2
Reaction time trials correct on left0.30.61.50.40.70.90.9-0.5-0.30.5-1.2-0.6-1.20.11.2
Reaction time trials on left0.40.81.70.50.81.01.1-0.6-0.30.6-1.3-0.6-1.30.11.3
Reaction time mean0.20.42.00.3-0.30.40.4-0.30.70.70.20.70.5-1.4-0.3
Reaction time mean AUC0.30.52.20.3-0.40.20.2-0.20.90.60.30.90.7-1.5-0.5
Median of all reaction times0.20.31.1-0.3-0.7-0.2-0.30.10.30.20.50.60.9-1.1-0.6
Reaction time omissions1.11.63.21.81.31.61.6-1.21.21.7-0.90.7-0.9-0.90.4
Reaction time false alarm rate0.50.73.8-0.50.0-0.8-0.9-0.2-1.0-0.20.9-0.90.21.9-0.4
Reaction time premature initiation rate2.23.16.82.02.61.91.8-2.0-0.21.6-1.3-1.1-2.31.81.4
Reaction time premature initiations3.05.49.22.43.02.62.5-2.7-0.42.3-2.3-1.4-3.01.62.2
Std. dev. reaction times0.61.12.61.40.61.31.3-0.81.31.3-0.41.0-0.2-1.60.2
Reaction time trials completed0.40.81.70.50.81.01.1-0.6-0.30.6-1.3-0.6-1.30.11.3
Reaction time trials AUC0.30.51.40.40.70.80.8-0.4-0.30.4-1.1-0.7-1.10.31.2
Run reversals in cocaine runway, females0.90.93.60.51.1-0.4-0.50.70.7-0.81.20.70.31.9-1.2
Run reversals in cocaine runway, males0.70.72.1-0.6-0.50.00.1-0.5-1.40.2-0.8-1.4-1.00.31.4
Latency to leave start box in cocaine runway0.91.02.1-0.2-0.2-0.9-0.81.31.0-1.21.01.31.5-0.3-1.4
Latency to leave start box in cocaine runway, F0.40.41.4-0.20.0-0.5-0.60.50.6-0.40.60.81.1-0.3-1.2
Latency to leave start box in cocaine runway, M0.40.41.30.2-0.1-0.4-0.21.20.8-1.10.50.80.50.0-0.4
Std. dev. time between licks in bursts0.60.83.8-0.20.6-0.0-0.1-0.6-1.30.10.1-1.5-0.91.90.8
Total sessions with >9 infusions0.80.92.4-0.2-0.2-0.6-0.61.51.1-1.50.71.31.1-0.4-1.0
Short access day 1 total inactive lever presses1.31.83.6-1.6-1.8-1.9-1.81.1-0.7-1.21.5-0.11.30.5-0.9
Short access day 10 total inactive lever presses0.20.51.3-0.8-0.5-0.8-0.9-0.5-1.00.60.8-0.70.31.1-0.3
Short access day 1 total infusions2.02.75.1-1.5-1.5-1.9-1.92.20.4-2.31.91.11.8-0.1-1.6
Short access day 10 total infusions3.03.97.4-0.9-1.0-1.7-1.62.71.9-2.61.82.42.5-1.0-2.3
Short access total infusions1.82.25.1-0.9-0.8-1.5-1.42.21.1-2.31.51.61.6-0.2-1.6
Short access day 1 locomotion1.62.03.3-1.5-1.5-1.7-1.71.80.0-1.71.70.61.5-0.3-1.3
Short access day 10 total locomotion1.22.23.3-1.3-1.5-1.5-1.41.80.8-1.71.51.41.8-1.3-1.5
Short access total locomotion2.02.54.4-1.5-1.6-1.7-1.62.10.6-2.01.61.21.8-1.0-1.5
One hour access (0.3 mA shock)4.04.69.9-3.1-3.2-2.7-2.62.4-1.0-2.31.80.02.0-0.7-1.0
Compulsive drug intake3.33.97.11.52.21.71.5-2.6-1.22.0-2.0-2.0-2.22.71.5
One hour access (shock baseline)4.36.714.5-3.3-3.8-3.0-2.83.1-0.2-2.62.21.02.7-2.3-1.5
Social response proportion0.50.51.31.10.80.90.9-0.50.80.6-0.60.5-0.6-0.80.3
Social responses0.40.50.90.60.70.80.8-0.9-0.20.8-0.9-0.4-0.80.00.8
Social time0.60.81.70.60.81.00.9-1.0-0.31.1-1.3-0.7-1.10.31.0
Soleus weight2.26.414.6-3.8-3.3-3.4-3.32.2-2.1-2.52.3-0.92.40.9-1.2
Bone: stiffness1.52.48.02.21.51.41.50.52.8-0.2-0.82.3-0.2-1.7-0.5
Tibialis anterior weight6.120.839.26.35.76.16.2-4.03.04.1-4.90.9-4.6-1.23.6
Time to tail flick, vehicle, before self-admin0.40.41.10.30.40.10.10.71.1-0.50.81.00.4-0.5-0.5
Time to tail flick, vehicle, after self-admin0.71.02.50.61.0-0.2-0.31.01.6-1.20.61.50.60.7-1.4
Time to tail flick, test, before self-admin2.82.94.8-1.5-1.2-2.1-2.22.1-0.0-2.22.00.61.71.0-1.9
Time to tail flick, test, after self-admin0.10.10.80.2-0.10.40.50.00.30.1-0.30.30.2-0.90.4
Delta time to tail flick, vehicle, before/after SA0.20.20.60.60.80.10.00.10.6-0.4-0.10.50.00.8-0.5
Delta time to tail flick, test, before/after SA4.04.17.01.41.02.52.6-2.4-0.42.6-2.6-1.1-2.0-1.62.7
Tibia length1.02.78.71.80.62.12.3-0.11.80.5-1.81.3-0.8-2.91.3
Ambulatory time before self-admin0.71.03.60.80.10.40.50.61.7-0.4-0.21.70.8-1.9-0.6
Ambulatory time after self-admin0.40.52.4-0.3-0.7-0.5-0.50.30.4-0.40.20.71.6-0.9-0.9
Bone: tissue strength0.10.10.20.2-0.2-0.1-0.00.30.4-0.10.30.40.2-0.4-0.3
Total heroin consumption3.23.77.12.72.42.52.4-1.91.62.1-2.20.7-1.7-0.80.8
Bone: trabecular number0.81.34.81.20.50.40.50.92.2-0.9-0.02.10.6-1.3-1.0
Bone: trabecular spacing0.50.61.9-1.0-0.3-0.6-0.7-0.6-1.30.40.2-1.2-0.11.40.1
Bone: trabecular thickness0.70.81.5-0.5-0.7-1.0-1.01.10.5-1.10.90.91.2-0.2-1.2
Bone: trabecular tissue density1.72.56.8-2.6-2.5-2.0-2.01.1-1.7-1.11.2-0.81.3-0.2-0.4
Water consumed over 24 hours1.01.42.91.21.31.41.3-1.7-0.11.6-1.3-0.6-1.30.20.8
Number of responses in last shaping day0.30.30.7-0.20.10.10.1-0.8-0.70.6-0.6-0.8-0.40.70.4