Hub : Genes

Cdc42ep2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL mRNA stability Cdc42ep2 0.05 0.03 1.4e-04 0.04 0.04 0.03 0.04 1.5e-05 9.0e-05 9.3e-04 6.6e-05
2 OFC alternative TSS XM_063264396.1 0.12 0.08 9.4e-03 0.04 0.03 0.02 0.03 5.1e-02 6.5e-02 9.6e-02 6.5e-02
3 OFC alternative TSS XM_063264396.1 0.13 0.08 8.5e-03 0.05 0.05 0.05 0.12 2.3e-02 2.1e-02 3.0e-02 9.8e-04
4 NAcc mRNA stability Cdc42ep2 0.04 0.02 1.8e-06 0.01 0.04 0.03 0.03 2.2e-03 1.5e-06 2.1e-05 1.3e-05
5 LHb mRNA stability Cdc42ep2 0.17 0.1 2.7e-03 0.08 0.12 0.12 0.11 5.5e-03 7.0e-04 9.0e-04 1.4e-03
6 LHb gene expression Cdc42ep2 0.14 0.1 8.0e-03 0.1 0.08 0.1 0.1 2.8e-03 6.0e-03 2.1e-03 2.1e-03
7 Adipose gene expression Cdc42ep2 0.06 0.04 1.5e-03 0.02 0.02 0.02 0.02 1.9e-03 1.8e-03 4.5e-03 2.2e-03
8 Adipose mRNA stability Cdc42ep2 0.04 0.02 2.0e-03 0.01 0.01 0.02 0.01 1.9e-02 7.7e-03 5.2e-03 9.2e-03
9 pVTA gene expression Cdc42ep2 0.03 0.02 6.7e-03 0.02 0.02 0.02 0.02 7.7e-03 1.0e-02 1.2e-02 1.7e-02
10 NAcc gene expression Cdc42ep2 0.04 0.02 1.1e-04 0.02 0.03 0.03 0.03 1.2e-04 3.4e-05 9.5e-05 8.4e-05
11 Brain gene expression Cdc42ep2 0.05 0.03 1.5e-04 0.04 0.03 0.03 0.01 1.0e-04 1.5e-03 4.4e-04 7.2e-02
12 Adipose intron excision ratio chr1_212632764_212634091 0.22 0.11 1.8e-03 0.03 0.02 0.02 0.02 7.3e-04 3.6e-03 2.8e-03 6.3e-03
13 Brain mRNA stability Cdc42ep2 0.07 0.05 2.4e-04 0.03 0.04 0.01 0.03 4.8e-04 1.2e-04 2.4e-02 2.0e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density0.61.13.8-0.9-0.70.70.0-0.01.01.91.2-0.31.9-0.80.4-1.3
Area under the delay curve0.20.31.30.2-0.20.2-0.6-0.70.30.30.4-0.80.4-0.4-0.7-1.2
BMI with tail1.76.122.1-2.5-2.02.00.20.22.04.72.0-1.94.4-1.60.5-3.0
BMI without tail0.31.95.2-1.4-1.71.70.20.00.52.30.7-1.12.0-0.9-0.8-1.8
Body weight1.35.613.7-3.7-3.63.62.42.4-0.33.6-0.20.72.51.10.0-0.3
Weight adjusted by age0.51.62.7-1.4-1.51.51.61.6-0.90.7-1.31.40.21.60.81.0
Bone surface2.34.412.6-3.2-2.22.22.22.30.13.60.11.52.80.72.1-0.1
Bone volume1.12.38.8-1.8-1.01.01.01.10.93.00.80.62.7-0.42.0-0.8
Breakpoint value in progressive ratio session1.22.14.7-2.2-1.71.71.81.8-1.11.6-1.11.51.01.11.00.4
Number of licking bursts0.10.20.4-0.6-0.40.40.60.6-0.20.6-0.30.10.40.40.50.1
Context. condit. distance diff. score1.21.53.01.71.2-1.2-1.7-1.71.0-0.91.2-1.2-0.4-1.1-0.9-1.0
Locomotion velocity, session 10.30.31.10.0-0.60.60.20.1-0.6-0.7-0.20.3-0.80.7-1.00.6
Locomotion distance, session 10.40.61.2-0.7-1.11.10.0-0.10.41.10.6-0.70.9-0.2-0.7-0.9
Locomotion velocity, session 21.21.43.7-1.8-1.91.91.21.2-0.21.7-0.10.51.10.6-0.0-0.1
Locomotion distance, session 20.40.61.9-1.0-1.41.40.30.20.11.00.2-0.70.7-0.0-0.8-0.7
Locomotion velocity, session 30.91.03.00.30.2-0.2-1.0-1.01.60.71.7-1.20.9-0.7-0.7-1.1
Locomotion distance, session 30.00.00.10.00.1-0.1-0.2-0.20.2-0.10.3-0.3-0.10.1-0.3-0.1
Stereotopy head waving bouts, day 31.31.53.90.90.4-0.4-1.4-1.41.80.31.9-2.00.6-1.0-1.1-1.3
Stereotopy head waving duration, day 30.91.12.11.00.8-0.8-1.2-1.21.40.21.4-1.30.5-1.1-0.3-1.0
Locomotion velocity, session 71.92.14.40.70.6-0.6-1.4-1.42.11.11.8-1.91.4-1.8-0.2-2.0
Locomotion distance, session 70.40.51.40.0-0.30.3-0.7-0.70.90.30.8-0.90.3-0.5-1.2-1.0
Stereotopy head waving bouts, day 70.50.61.60.20.5-0.5-0.4-0.30.91.00.7-0.51.2-0.91.1-0.9
Stereotopy head waving duration, day 70.50.72.6-0.8-0.50.50.50.50.21.6-0.00.21.5-0.41.3-0.7
Locomotion velocity, session 81.11.32.7-1.1-1.61.61.11.1-1.0-0.3-0.60.8-0.81.6-1.11.2
Locomotion distance, session 80.71.02.50.60.3-0.3-1.1-1.11.50.61.6-1.40.8-1.0-0.4-1.2
Degree of sensitization distance0.40.51.20.0-0.20.2-0.5-0.51.10.71.0-0.90.7-0.7-0.6-0.9
Degree of sensitization stereotypy0.50.62.4-0.7-0.10.10.50.50.21.4-0.00.41.4-0.41.5-0.5
Conditioned locomotion0.91.12.1-1.4-1.41.41.31.3-0.80.7-0.71.00.21.3-0.10.7
Cocaine response after cond. corrected0.71.12.21.50.8-0.8-1.4-1.40.8-1.11.0-0.9-0.8-0.5-1.5-0.4
Cocaine response after cond. not corrected0.60.81.51.20.7-0.7-1.2-1.20.8-0.90.9-0.9-0.6-0.5-1.2-0.3
Cocaine response before conditioning0.50.51.3-1.1-0.50.50.91.0-0.40.9-0.60.50.70.11.10.3
Saline control response2.33.27.0-2.5-2.62.62.22.2-1.51.0-1.41.10.11.8-0.51.2
Bone: connectivity density1.21.96.1-2.2-1.61.61.11.20.22.50.40.72.00.10.7-0.7
Bone: cortical apparent density0.30.51.8-0.3-0.30.30.60.5-1.3-0.5-1.30.6-0.70.6-0.10.4
Bone: cortical area0.40.71.3-1.1-0.90.91.11.10.01.0-0.00.90.70.70.90.6
Bone: cortical porosity0.10.10.4-0.3-0.40.40.20.2-0.00.60.1-0.00.5-0.20.1-0.4
Bone: cortical porosity0.20.30.7-0.7-0.80.80.50.5-0.20.8-0.00.30.60.10.0-0.2
Bone: cortical thickness2.84.76.6-2.2-2.52.52.62.5-2.6-0.2-2.42.5-1.12.5-0.52.1
Bone: cortical thickness1.31.62.8-0.7-1.21.20.90.9-1.7-1.1-1.41.2-1.51.6-1.51.2
Bone: cortical tissue density0.40.72.3-0.5-0.50.50.80.7-1.5-0.5-1.50.7-0.80.8-0.10.6
Condit. Reinf. active minus inactive responses0.10.10.3-0.3-0.50.50.10.0-0.00.4-0.1-0.40.3-0.3-0.3-0.5
Condit. Reinf. active-inactive response ratio0.10.10.30.0-0.20.20.10.0-0.4-0.1-0.60.2-0.2-0.3-0.1-0.2
Condit. Reinf. active responses0.30.30.7-0.1-0.00.0-0.3-0.30.70.80.7-0.70.9-0.70.1-0.9
Condit. Reinf. inactive responses0.81.02.60.10.6-0.6-0.8-0.71.51.11.6-1.21.3-0.90.4-1.0
Incentive salience index mean0.30.41.1-0.5-0.60.6-0.0-0.10.41.00.5-0.70.9-0.6-0.2-0.9
Condit. Reinf. lever presses0.40.62.4-0.9-0.40.40.30.30.71.60.8-0.31.4-0.40.6-0.6
Condit. Reinf. active minus inactive responses0.20.41.20.10.8-0.8-0.2-0.10.70.60.5-0.50.7-0.71.1-0.3
Condit. Reinf. active-inactive response ratio1.11.83.90.81.6-1.6-0.9-0.82.00.91.7-1.21.4-1.41.6-0.8
Condit. Reinf. active responses0.10.20.7-0.60.1-0.10.20.2-0.00.8-0.1-0.20.8-0.40.8-0.5
Condit. Reinf. inactive responses0.40.61.5-1.0-1.11.10.60.4-1.20.2-1.00.3-0.00.4-0.6-0.3
Condit. Reinf. lever presses1.11.53.6-1.8-0.80.81.51.6-0.21.9-0.51.01.50.61.70.3
Condit. Reinf. lever reinforcers received0.20.30.9-0.9-0.20.20.60.6-0.30.9-0.50.10.7-0.11.0-0.2
Conditioned reinforcement - actives0.20.86.70.10.6-0.60.50.70.60.7-0.00.50.70.22.60.8
Conditioned reinforcement - inactives0.82.36.61.92.6-2.6-1.5-1.31.3-0.60.9-0.60.2-1.22.1-0.3
Conditioned locomotion3.55.113.03.33.6-3.6-2.6-2.41.7-1.81.3-1.8-0.7-1.81.2-0.5
Patch foraging indifference point 0 sec0.00.10.2-0.20.1-0.1-0.2-0.20.30.10.20.20.2-0.5-0.0-0.3
Patch foraging indifference point AUC1.12.54.8-2.0-1.31.32.02.1-1.61.1-1.72.20.51.21.51.1
Delay disc. indifference point, 0s delay0.80.92.21.0-0.00.0-1.1-1.20.90.31.1-1.20.5-1.1-1.1-1.5
Delay disc. indifference point, 16s delay0.60.81.50.71.1-1.1-1.1-1.10.90.10.8-1.20.5-0.90.4-1.2
Delay disc. indifference point, 2s delay0.30.41.00.50.3-0.3-0.6-0.61.00.40.9-0.70.6-0.50.1-0.7
Delay disc. indifference point, 24s delay0.20.30.80.2-0.20.2-0.1-0.2-0.6-0.9-0.40.1-0.90.8-0.90.2
Delay disc. indifference point, 4s delay0.40.42.00.4-0.30.3-0.7-0.80.3-0.10.5-1.1-0.0-0.2-1.4-0.9
Delay disc. indifference point, 8s delay0.10.21.40.2-0.40.4-0.4-0.5-0.1-0.20.2-0.5-0.1-0.1-1.2-0.7
Indifference point function ln k2.47.413.03.62.7-2.7-3.6-3.62.4-2.52.8-3.1-1.5-1.8-2.4-1.4
Indifference point function log k2.47.413.03.62.7-2.7-3.6-3.62.4-2.52.8-3.1-1.5-1.8-2.4-1.4
Patch foraging total patch changes 0 sec0.00.10.2-0.2-0.20.20.0-0.0-0.1-0.4-0.20.5-0.40.1-0.50.2
Patch foraging total patch changes 12 sec2.63.48.2-2.9-2.32.32.22.2-1.81.7-1.82.00.91.30.60.5
Patch foraging total patch changes 18 sec0.20.51.2-1.1-0.70.70.70.7-0.21.1-0.30.60.9-0.00.8-0.1
Patch foraging total patch changes 24 sec0.72.33.9-1.9-1.71.71.92.0-1.50.4-1.71.7-0.21.40.31.4
Patch foraging total patch changes 6 sec0.50.92.8-1.7-1.51.51.00.9-0.60.7-0.51.10.30.4-0.50.2
Patch foraging time to switch 0 sec0.62.18.8-1.7-1.11.10.60.60.83.00.6-0.42.7-0.81.2-1.5
Patch foraging water rate 0 sec0.93.310.42.82.4-2.4-1.6-1.50.3-3.20.6-0.3-2.60.0-0.91.1
Patch foraging water rate 12 sec1.76.820.74.02.7-2.7-2.6-2.60.5-4.51.2-1.3-3.7-0.0-2.40.9
Patch foraging water rate 18 sec1.12.45.72.41.3-1.3-1.7-1.80.7-2.41.1-1.1-1.9-0.3-1.90.2
Patch foraging water rate 24 sec2.23.17.82.82.1-2.1-1.8-1.80.8-2.81.3-0.9-2.2-0.2-1.40.6
Patch foraging water rate 6 sec2.73.912.12.71.9-1.9-1.8-1.80.3-3.51.1-1.0-2.90.5-2.40.9
Seeking ratio, delayed vs. immediate footshock0.30.51.70.10.4-0.4-0.8-0.80.50.30.3-1.30.5-0.7-0.3-1.3
Distance traveled before self-admin0.30.82.6-0.9-0.50.50.60.60.31.60.20.41.5-0.51.5-0.5
Distance traveled after self-admin0.20.30.9-0.6-0.30.30.60.6-0.80.3-0.71.00.2-0.40.70.1
Extensor digitorum longus weight3.815.333.5-5.8-5.65.64.94.8-2.73.8-2.73.12.03.10.31.5
Bone: elastic displacement1.11.45.41.10.4-0.4-0.4-0.4-0.9-2.3-0.40.1-2.20.9-1.71.2
Bone: elastic work1.31.82.7-1.0-1.61.61.11.1-1.7-0.7-1.11.0-1.31.7-1.61.3
Bone: endosteal estimation1.74.311.41.11.4-1.4-2.0-1.83.41.53.4-2.32.1-2.10.5-2.0
Bone: endosteal perimeter2.25.413.61.41.9-1.9-2.1-1.93.71.83.5-2.22.5-2.51.5-2.1
Epididymis fat weight1.68.015.13.63.9-3.9-3.1-2.93.5-0.73.5-2.60.5-2.81.4-1.3
Delta time in closed arm before/after self-admin0.90.95.0-0.3-1.21.20.20.1-0.7-0.7-0.30.1-1.01.0-2.20.4
Delta time in open arm before/after self-admin0.50.64.2-0.50.2-0.20.70.8-0.30.8-0.40.80.7-0.42.10.3
Diff in mean of infusions in LGA sessions0.30.61.2-0.9-0.80.80.90.9-0.80.1-0.91.1-0.20.6-0.10.7
Delay discount exponential model param0.10.20.9-0.10.3-0.30.40.5-0.1-0.2-0.20.7-0.30.20.70.9
Extinction: sum of active levers before priming0.91.43.5-1.8-1.61.61.11.1-0.31.9-0.60.61.40.30.6-0.5
Active lever presses in extinction session 62.22.24.2-1.8-1.41.41.92.0-0.51.7-0.71.71.11.11.71.0
Bone: final force1.32.15.0-2.2-1.91.91.71.8-0.21.9-0.21.21.21.20.80.5
Bone: final moment1.21.94.5-2.1-1.81.81.71.7-0.21.8-0.21.11.11.20.70.5
Food consumed during 24 hour testing period0.20.51.1-0.10.2-0.20.70.8-0.6-0.3-0.91.0-0.50.70.91.0
Glucose2.94.67.72.11.8-1.8-2.7-2.72.60.22.8-2.51.1-2.5-0.6-2.4
Heart weight2.13.57.61.40.5-0.5-2.3-2.32.20.52.8-2.41.0-1.9-1.8-2.3
Delay discount hyperbolic model param0.20.21.0-0.20.2-0.20.40.5-0.3-0.3-0.40.7-0.40.30.61.0
Intermittent access intake day 1-15 change0.21.03.21.31.8-1.8-0.8-0.60.8-0.60.3-0.3-0.1-0.71.60.2
Intermittent access intake escalation0.20.93.21.21.7-1.7-0.6-0.40.7-0.50.2-0.1-0.1-0.61.80.4
Intermittent access intake escalation 20.50.82.81.11.6-1.6-0.5-0.40.5-0.40.1-0.0-0.1-0.71.70.3
Intermitt. access day 1 inactive lever presses0.00.20.80.40.5-0.5-0.2-0.2-0.7-0.4-0.90.2-0.2-0.30.3-0.1
Intermitt. access day 15 inactive lever presses0.41.94.11.52.0-2.0-1.5-1.31.40.11.1-1.10.7-1.61.6-0.9
Intermitt. access escalation Index0.92.85.02.21.7-1.7-2.2-2.21.5-1.11.9-1.7-0.4-1.6-0.9-1.4
Intermittent access day 1 total infusions2.06.011.92.12.2-2.2-2.6-2.53.51.23.3-2.52.1-2.91.2-2.5
Intermittent access day 15 total infusions2.46.011.52.93.4-3.4-2.6-2.43.1-0.02.5-1.91.1-2.62.3-1.3
Intermittent access terminal intake (last 3 days)3.76.412.62.63.2-3.2-2.5-2.33.50.63.0-1.91.6-2.82.5-1.5
Intermittent access total infusions4.85.711.92.32.7-2.7-2.5-2.33.50.83.1-2.01.8-2.71.8-1.8
Intermittent access day 1 locomotion2.03.66.11.81.9-1.9-2.1-2.02.50.72.3-2.11.4-2.30.9-1.9
Intermittent access day 15 total locomotion1.45.610.42.43.2-3.2-2.3-2.12.90.42.3-1.81.5-2.52.8-1.5
Intermittent access total locomotion7.99.516.72.93.7-3.7-3.1-2.94.10.93.6-2.72.2-3.52.9-2.4
Intermittent access standard deviation0.20.92.71.61.6-1.6-1.0-0.90.5-0.80.3-0.2-0.3-0.80.90.2
Left kidney weight0.43.15.91.91.7-1.7-2.0-1.92.30.32.4-1.41.0-2.40.5-1.6
Right kidney weight0.10.91.81.31.3-1.3-1.0-0.91.1-0.31.2-0.60.1-0.90.5-0.2
Cocaine induced anxiety0.10.21.1-0.20.0-0.00.20.3-0.00.5-0.30.30.5-0.41.1-0.0
Post-drug Anxiety0.50.51.4-1.2-0.70.70.91.0-0.30.8-0.60.60.50.60.70.4
Baseline Anxiety0.40.71.9-0.8-0.90.90.70.6-0.8-0.4-0.80.5-0.71.4-1.30.7
Tail length0.52.95.3-1.0-1.91.91.81.7-2.3-0.9-2.11.8-1.51.9-1.11.8
Length with tail1.56.812.0-2.9-3.53.53.23.1-2.60.5-2.42.7-0.73.0-0.92.3
Length without tail1.15.79.7-2.8-3.13.12.82.8-2.30.2-1.82.3-0.93.1-1.02.3
Times rat made contact with spout0.40.51.4-0.6-1.01.00.60.5-1.20.0-0.90.5-0.20.6-0.6-0.1
Lifetime Intake3.44.29.02.02.2-2.2-2.2-2.13.00.72.8-1.81.5-2.31.2-1.6
Liver weight, left0.50.91.81.40.9-0.9-1.1-1.10.9-1.01.2-0.9-0.7-0.3-1.00.0
Liver weight, right1.42.44.52.11.2-1.2-2.0-2.01.2-1.71.5-1.9-1.2-0.5-2.0-0.3
Locomotor activity1.32.06.71.81.2-1.2-1.3-1.3-0.2-2.60.4-0.4-2.20.5-1.90.7
Locomotor testing distance1.12.89.52.11.3-1.3-1.5-1.5-0.3-3.10.5-0.4-2.70.5-2.40.9
Locomotor testing rearing0.62.27.12.11.1-1.1-1.5-1.6-0.4-2.70.4-0.4-2.2-0.0-2.10.3
Locomotion in novel chamber3.34.48.52.82.9-2.9-2.4-2.32.5-0.92.2-2.10.0-2.00.7-0.9
Locomotion in novel chamber post-restriction0.92.85.72.32.4-2.4-2.0-1.91.8-0.71.6-1.40.1-1.70.8-0.9
Fecal boli incidents, locomotor time 10.20.53.0-0.10.5-0.50.20.30.51.00.10.41.0-0.51.7-0.1
Change in fecal boli incidents, locomotor task0.40.42.7-0.1-0.50.5-0.4-0.50.2-0.30.5-0.8-0.30.2-1.6-0.3
Time >=10cm from walls, locomotor time 12.73.48.00.71.4-1.4-1.3-1.22.81.82.4-1.72.4-2.21.8-1.8
Bouts of movement, locomotor time 11.72.26.7-1.4-1.01.01.81.7-2.40.2-2.61.8-0.31.00.90.8
Total resting periods, locomotor time 11.21.44.3-1.2-0.60.61.41.4-1.90.4-2.11.30.00.61.20.5
Rest time, locomotor task time 10.50.82.21.41.5-1.5-1.0-0.90.6-0.80.7-0.4-0.3-0.80.40.1
Distance moved, locomotor task time 10.10.41.0-0.3-0.40.4-0.2-0.30.80.90.7-0.60.9-0.5-0.2-1.0
Vertical activity count, locomotor time 10.10.71.31.01.0-1.0-1.1-1.10.9-0.70.8-0.8-0.3-0.5-0.4-0.5
Time >=10cm from walls, locomotor time 20.10.42.7-0.10.2-0.20.30.40.30.9-0.10.20.9-0.51.6-0.3
Bouts of movement, locomotor time 20.10.51.7-0.8-0.60.60.80.7-1.30.3-1.20.40.10.70.3-0.0
Total resting periods, locomotor time 20.10.20.9-0.5-0.30.30.40.3-0.90.4-0.80.10.30.20.4-0.3
Rest time, locomotor task time 21.11.83.51.91.7-1.7-1.7-1.71.3-0.51.7-1.30.1-1.4-0.2-0.8
Distance moved, locomotor task time 20.81.12.0-1.2-1.21.21.41.3-1.10.2-1.41.2-0.31.10.20.8
Vertical activity count, locomotor time 20.41.03.00.0-0.30.30.50.5-0.9-1.5-1.00.9-1.71.2-0.91.4
Light reinforcement 10.00.20.60.40.1-0.1-0.0-0.0-0.5-0.8-0.40.5-0.70.2-0.20.4
Light reinforcement 20.41.03.21.01.4-1.4-0.6-0.51.40.21.0-0.60.6-0.61.8-0.1
Bone: marrow area1.94.612.01.21.4-1.4-2.1-2.03.41.53.5-2.52.1-2.20.4-2.1
Bone: maximum diameter0.40.72.9-0.50.1-0.10.60.71.01.30.80.41.20.11.70.4
Bone: maximum force1.63.19.9-2.6-2.02.01.71.80.53.10.40.72.50.51.5-0.3
Bone: maximum moment1.52.89.0-2.5-1.91.91.61.70.53.00.50.62.40.51.3-0.3
Mean time between licks in bursts0.21.03.2-0.6-1.31.30.50.5-1.0-0.8-0.70.1-1.21.2-1.80.8
Mean num. licks in bursts0.10.20.70.50.1-0.1-0.5-0.6-0.4-0.8-0.1-0.0-0.6-0.3-0.8-0.3
Cd content in liver1.11.23.31.11.8-1.8-1.0-0.91.1-0.00.7-0.30.5-1.21.5-0.6
Co content in liver1.51.87.11.40.7-0.7-0.5-0.6-1.3-2.7-1.10.1-2.50.5-1.70.9
Cu content in liver0.20.21.00.10.2-0.2-0.4-0.5-0.10.3-0.0-0.50.5-0.70.0-1.0
Fe content in liver0.20.20.8-0.4-0.30.30.50.6-0.0-0.10.00.4-0.30.9-0.10.9
K content in liver0.40.41.1-0.7-1.11.10.10.10.40.80.7-0.40.7-0.1-0.8-0.5
Mg content in liver0.60.61.60.60.1-0.1-0.9-1.00.7-0.21.0-1.10.0-0.8-1.2-0.9
Mn content in liver1.71.94.5-2.1-1.41.41.92.0-0.61.5-0.81.00.91.11.20.9
Na content in liver0.60.71.6-0.6-0.80.81.01.0-0.8-0.1-0.61.3-0.40.9-0.21.2
Rb content in liver1.31.53.11.61.1-1.1-1.7-1.80.8-1.21.1-0.9-0.7-1.2-1.3-0.9
Se content in liver0.40.51.60.41.0-1.0-0.3-0.20.90.30.7-0.30.5-0.41.3-0.2
Sr content in liver2.52.13.9-1.6-1.51.52.02.0-1.60.4-1.61.7-0.21.50.81.5
Zn content in liver0.20.20.6-0.5-0.80.80.40.3-0.50.2-0.50.50.1-0.1-0.1-0.3
Bone: minimum diameter2.14.18.71.11.2-1.2-2.0-1.92.91.52.9-2.22.2-2.50.5-2.5
Time in familiar zone, hab. session 10.50.61.50.50.5-0.5-0.8-0.81.00.31.0-1.20.5-0.9-0.1-0.9
Time in novel zone, hab. session 10.60.62.10.4-0.10.10.00.0-0.7-1.4-0.40.6-1.40.9-1.10.9
Total zone transitions, hab. session 10.30.41.0-1.0-0.90.90.70.6-0.60.9-0.60.40.60.10.2-0.3
Total locomotion distance, hab. session 10.60.81.40.60.5-0.5-1.0-1.01.20.61.2-1.10.8-1.2-0.0-1.2
Locomotion velocity, hab. session 10.20.30.90.10.1-0.1-0.5-0.50.70.70.7-0.60.8-0.80.1-1.0
Time in familiar zone, hab. session 20.60.62.6-0.1-0.50.50.00.0-0.5-1.1-0.10.2-1.31.0-1.60.8
Time in novel zone, hab. session 20.30.30.9-0.20.0-0.00.0-0.00.20.9-0.0-0.20.9-0.70.8-0.8
Total zone transitions, hab. session 21.01.34.2-1.3-1.51.50.30.30.32.10.5-0.81.8-0.6-0.2-1.4
Total locomotion distance, hab. session 21.01.33.00.1-0.30.3-0.9-1.01.31.21.5-1.71.3-1.2-0.6-1.7
Locomotion velocity, hab. session 21.21.73.60.30.0-0.0-1.1-1.11.61.31.7-1.91.6-1.5-0.2-1.9
Novel to familiar place preference ratio0.81.03.8-1.1-0.30.31.01.0-0.21.7-0.60.41.5-0.12.0-0.2
Novelty place preference0.50.63.0-0.7-0.00.00.60.7-0.11.3-0.40.31.3-0.31.7-0.3
Time in novel zone, NPP test0.40.42.1-0.6-0.00.00.50.6-0.11.1-0.30.21.1-0.31.5-0.3
Total zone transitions, NPP test1.11.63.8-1.9-1.91.91.31.3-0.41.9-0.40.71.30.30.3-0.3
Total locomotion distance, NPP test0.30.41.2-0.2-0.40.4-0.3-0.40.70.90.8-0.80.9-0.7-0.4-1.1
Locomotion velocity, NPP test0.30.41.1-0.3-0.40.4-0.2-0.30.51.00.5-0.61.0-0.7-0.1-1.1
Intraocular pressure0.61.03.41.21.9-1.9-0.4-0.2-0.0-0.8-0.40.5-0.5-0.21.60.7
Delta distance traveled before/after self-admin0.70.72.30.3-0.00.0-0.0-0.1-1.1-1.5-0.80.4-1.50.3-1.50.7
Delta ambulatory time before/after self-admin0.40.82.20.1-0.30.30.10.1-1.2-1.4-0.90.5-1.50.6-1.50.8
Parametrial fat weight3.07.210.63.03.2-3.2-3.2-3.13.3-0.13.1-2.81.1-3.10.7-2.3
Pavlov. Cond. lever latency0.20.20.80.50.5-0.5-0.2-0.2-0.2-0.9-0.30.3-0.80.2-0.10.5
Pavlov. Cond. magazine entry latency0.50.72.3-0.5-0.30.30.0-0.00.41.50.4-0.71.5-0.90.7-1.2
Pavlov. Cond. change in total contacts0.60.72.2-0.30.3-0.30.00.00.41.30.2-0.41.5-0.91.5-1.0
Pavlov. Cond. index score0.20.20.7-0.5-0.20.20.40.4-0.10.8-0.1-0.00.8-0.20.7-0.3
Pavlov. Cond. latency score0.10.20.7-0.3-0.20.20.10.10.20.80.2-0.40.8-0.40.4-0.6
Pavlov. Cond. lever contacts0.20.20.6-0.3-0.30.3-0.1-0.10.40.80.6-0.50.8-0.4-0.1-0.6
Pavlov. Cond. magazine entry number0.30.31.20.60.2-0.2-0.7-0.70.5-0.70.7-0.5-0.6-0.0-1.10.0
Pavlov. Cond. intertrial magazine entries0.30.31.10.81.0-1.0-0.4-0.4-0.0-0.7-0.1-0.1-0.5-0.30.60.2
Pavlov. Cond. lever-magazine prob. diff.0.30.41.3-0.7-0.40.40.50.4-0.01.1-0.1-0.01.0-0.30.8-0.5
Pavlov. Cond. response bias0.20.20.7-0.5-0.20.20.50.5-0.30.7-0.40.30.6-0.10.8-0.1
Pavlov. Cond. lever latency0.40.61.80.90.3-0.3-0.9-1.1-0.2-1.10.1-0.9-0.9-0.5-1.3-0.5
Pavlov. Cond. magazine entry latency1.92.75.9-2.4-2.02.02.01.9-1.12.1-1.21.61.50.91.0-0.0
Pavlov. Cond. change in total contacts0.71.85.8-1.7-0.50.51.41.4-0.12.3-0.61.02.00.02.4-0.3
Pavlov. Cond. index score1.21.94.8-1.9-1.11.11.61.6-0.32.2-0.61.21.70.51.70.0
Pavlov. Cond. latency score1.01.64.6-1.7-1.01.01.41.5-0.02.1-0.41.11.70.31.7-0.0
Pavlov. Cond. lever contacts0.40.61.8-0.9-0.30.31.01.10.11.1-0.21.00.90.41.30.4
Pavlov. Cond. magazine entry number3.64.710.23.22.4-2.4-2.8-2.81.5-2.61.9-2.1-1.7-1.3-1.7-0.4
Pavlov. Cond. intertrial magazine entries0.30.71.31.11.1-1.1-1.1-1.00.9-0.70.9-0.7-0.3-0.7-0.0-0.2
Pavlov. Cond. lever-magazine prob. diff.1.42.25.1-2.1-1.31.31.81.8-0.52.3-0.81.41.70.61.80.1
Pavlov. Cond. response bias1.21.63.4-1.8-1.11.11.61.6-0.41.8-0.61.31.40.61.50.2
Time in closed arm before self-admin0.50.81.80.51.1-1.1-0.6-0.51.20.70.8-0.71.0-0.91.4-0.7
Time in closed arm after self-admin0.30.30.80.40.3-0.3-0.8-0.80.7-0.30.6-0.9-0.2-0.1-0.9-0.4
Time in open arm before self-admin1.31.69.70.6-0.70.7-0.5-0.7-0.9-1.9-0.5-0.3-1.90.5-3.10.1
Time in open arm after self-admin0.30.31.1-0.1-0.50.50.50.4-1.0-0.6-0.70.6-0.70.1-0.60.5
Bone: periosteal estimation0.61.54.6-0.10.4-0.4-0.5-0.32.11.72.1-0.81.8-0.91.1-0.8
Bone: periosteal perimeter0.40.92.6-0.4-0.00.0-0.00.11.51.61.4-0.41.6-0.51.1-0.6
Bone: post-yield work4.37.422.7-0.90.2-0.2-0.9-0.83.34.53.0-2.34.8-2.92.4-3.6
Progressive ratio test 1 active lever presses0.30.51.30.80.9-0.9-0.5-0.40.80.30.80.10.6-0.71.2-0.3
Progressive ratio test 1 breakpoint0.30.51.60.70.9-0.9-0.4-0.30.80.40.70.10.6-0.61.3-0.2
Progressive ratio test 1 inactive lever presses0.10.20.80.40.5-0.5-0.1-0.1-0.20.0-0.50.60.1-0.20.9-0.1
Progressive ratio test 2 active lever presses1.92.65.41.92.3-2.3-1.6-1.42.00.21.6-1.00.9-1.62.0-0.7
Progressive ratio test 2 breakpoint2.02.55.41.92.3-2.3-1.5-1.31.90.11.5-0.90.8-1.52.0-0.6
Progressive ratio test 2 inactive lever presses2.37.215.03.33.9-3.9-3.0-2.83.0-0.62.4-2.30.7-2.72.1-1.6
Incentive Sensitization - Responses0.20.71.70.10.5-0.5-0.4-0.31.31.11.1-0.61.2-0.81.1-0.7
Incentive Sensitization - Breakpoint0.30.81.90.30.7-0.7-0.6-0.51.40.91.1-0.71.2-0.91.1-0.7
Sum of active levers in priming session hrs 5-62.72.57.3-1.2-0.10.11.92.2-1.00.4-1.62.0-0.01.72.72.2
Progressive ratio0.61.87.0-1.1-0.90.90.20.11.22.61.1-0.72.5-0.90.9-1.7
Food seeking constrained by brief footshock0.10.10.6-0.4-0.30.30.10.1-0.1-0.2-0.2-0.2-0.30.7-0.80.2
Seeking ratio, punishment vs. effort0.92.07.81.30.8-0.8-0.7-0.8-0.9-2.8-0.6-0.1-2.60.7-2.01.1
Retroperitoneal fat weight5.424.246.46.86.1-6.1-6.4-6.34.8-3.35.2-5.0-1.1-4.2-1.1-2.6
Reaction time number correct0.20.61.5-0.4-0.70.70.90.9-0.6-0.3-0.51.2-0.61.2-0.11.2
Reaction time mean minus median0.42.75.8-2.4-1.51.52.12.1-0.92.3-1.50.81.70.62.10.3
Reaction time mean minus median AUC0.21.63.2-1.7-1.01.01.71.8-1.11.3-1.50.90.80.91.40.8
Reaction time num false alarms0.50.95.30.7-0.10.1-0.7-0.8-0.3-1.50.0-0.5-1.50.1-2.30.1
Reaction time num false alarms AUC0.30.74.6-0.0-0.70.7-0.1-0.3-0.7-1.1-0.5-0.2-1.20.5-2.10.2
Reaction time trials correct on left0.20.61.5-0.4-0.70.70.90.9-0.6-0.3-0.51.2-0.61.2-0.11.2
Reaction time trials on left0.20.81.7-0.5-0.80.81.01.1-0.6-0.3-0.61.3-0.61.3-0.11.3
Reaction time mean0.20.32.0-0.30.3-0.30.40.4-0.20.7-0.7-0.20.7-0.51.4-0.3
Reaction time mean AUC0.20.42.2-0.30.4-0.40.20.2-0.10.9-0.6-0.30.9-0.71.5-0.5
Median of all reaction times0.20.31.10.30.7-0.7-0.2-0.30.20.3-0.2-0.50.6-0.91.1-0.6
Reaction time omissions1.01.63.2-1.8-1.31.31.61.6-1.11.2-1.70.90.70.90.90.4
Reaction time false alarm rate0.50.63.80.5-0.00.0-0.8-0.9-0.1-1.00.2-0.9-0.9-0.2-1.9-0.4
Reaction time premature initiation rate2.23.46.8-2.0-2.62.61.91.8-2.1-0.2-1.61.3-1.12.3-1.81.4
Reaction time premature initiations1.95.89.2-2.4-3.03.02.62.5-2.8-0.4-2.32.3-1.43.0-1.62.2
Std. dev. reaction times0.31.12.6-1.4-0.60.61.31.3-0.71.3-1.30.41.00.21.60.2
Reaction time trials completed0.20.81.7-0.5-0.80.81.01.1-0.6-0.3-0.61.3-0.61.3-0.11.3
Reaction time trials AUC0.20.51.4-0.4-0.70.70.80.8-0.5-0.3-0.41.1-0.71.1-0.31.2
Run reversals in cocaine runway, females0.80.93.6-0.5-1.11.1-0.4-0.50.60.70.8-1.20.7-0.3-1.9-1.2
Run reversals in cocaine runway, males0.60.72.10.60.5-0.50.00.1-0.6-1.4-0.20.8-1.41.0-0.31.4
Latency to leave start box in cocaine runway0.70.92.10.20.2-0.2-0.9-0.81.31.01.2-1.01.3-1.50.3-1.4
Latency to leave start box in cocaine runway, F0.30.41.40.2-0.00.0-0.5-0.60.50.60.4-0.60.8-1.10.3-1.2
Latency to leave start box in cocaine runway, M0.40.41.4-0.20.1-0.1-0.4-0.21.20.81.1-0.50.8-0.5-0.0-0.4
Std. dev. time between licks in bursts0.40.83.80.2-0.60.6-0.0-0.1-0.6-1.3-0.1-0.1-1.50.9-1.90.8
Total sessions with >9 infusions0.70.92.40.20.2-0.2-0.6-0.61.51.11.5-0.71.3-1.10.4-1.0
Short access day 1 total inactive lever presses1.01.93.61.61.8-1.8-1.9-1.81.3-0.71.2-1.5-0.1-1.3-0.5-0.9
Short access day 10 total inactive lever presses0.10.51.30.80.5-0.5-0.8-0.9-0.3-1.0-0.6-0.8-0.7-0.3-1.1-0.3
Short access day 1 total infusions1.32.75.11.51.5-1.5-1.9-1.92.20.42.3-1.91.1-1.80.1-1.6
Short access day 10 total infusions2.23.77.80.91.0-1.0-1.7-1.62.81.92.6-1.82.4-2.51.0-2.3
Short access total infusions1.52.25.40.90.8-0.8-1.5-1.42.31.12.3-1.51.6-1.60.2-1.6
Short access day 1 locomotion1.22.03.41.51.5-1.5-1.7-1.71.80.01.7-1.70.6-1.50.3-1.3
Short access day 10 total locomotion0.62.23.71.31.5-1.5-1.5-1.41.90.81.7-1.51.4-1.81.3-1.5
Short access total locomotion1.62.54.61.51.6-1.6-1.7-1.62.10.62.0-1.61.2-1.81.0-1.5
One hour access (0.3 mA shock)4.25.09.93.13.2-3.2-2.7-2.62.5-1.02.3-1.80.0-2.00.7-1.0
Compulsive drug intake2.74.07.2-1.5-2.22.21.71.5-2.7-1.2-2.02.0-2.02.2-2.71.5
One hour access (shock baseline)2.87.314.53.33.8-3.8-3.0-2.83.2-0.22.6-2.21.0-2.72.3-1.5
Social response proportion0.40.51.3-1.1-0.80.80.90.9-0.50.8-0.60.60.50.60.80.3
Social responses0.40.50.9-0.6-0.70.70.80.8-0.9-0.2-0.80.9-0.40.8-0.00.8
Social time0.50.81.7-0.6-0.80.81.00.9-1.0-0.3-1.11.3-0.71.1-0.31.0
Soleus weight2.36.814.63.83.3-3.3-3.4-3.32.2-2.12.5-2.3-0.9-2.4-0.9-1.2
Bone: stiffness1.32.48.0-2.2-1.51.51.41.50.52.80.20.82.30.21.7-0.5
Tibialis anterior weight6.321.639.2-6.3-5.75.76.16.2-3.93.0-4.14.90.94.61.23.6
Time to tail flick, vehicle, before self-admin0.30.41.1-0.3-0.40.40.10.10.71.10.5-0.81.0-0.40.5-0.5
Time to tail flick, vehicle, after self-admin0.51.02.5-0.6-1.01.0-0.2-0.31.01.61.2-0.61.5-0.6-0.7-1.4
Time to tail flick, test, before self-admin2.42.84.81.51.2-1.2-2.1-2.22.0-0.02.2-2.00.6-1.7-1.0-1.9
Time to tail flick, test, after self-admin0.10.10.8-0.20.1-0.10.40.50.00.3-0.10.30.3-0.20.90.4
Delta time to tail flick, vehicle, before/after SA0.20.20.6-0.6-0.80.80.10.00.10.60.40.10.5-0.0-0.8-0.5
Delta time to tail flick, test, before/after SA3.13.97.0-1.4-1.01.02.52.6-2.3-0.4-2.62.6-1.12.01.62.7
Tibia length0.92.58.7-1.8-0.60.62.12.3-0.21.8-0.51.81.30.82.91.3
Ambulatory time before self-admin0.30.93.6-0.8-0.10.10.40.50.51.70.40.21.7-0.81.9-0.6
Ambulatory time after self-admin0.30.52.40.30.7-0.7-0.5-0.50.30.40.4-0.20.7-1.60.9-0.9
Bone: tissue strength0.10.10.2-0.20.2-0.2-0.1-0.00.30.40.1-0.30.4-0.20.4-0.3
Total heroin consumption3.33.97.1-2.7-2.42.42.52.4-1.91.6-2.12.20.71.70.80.8
Bone: trabecular number0.71.24.8-1.2-0.50.50.40.50.92.20.90.02.1-0.61.3-1.0
Bone: trabecular spacing0.40.61.91.00.3-0.3-0.6-0.7-0.5-1.3-0.4-0.2-1.20.1-1.40.1
Bone: trabecular thickness0.60.81.50.50.7-0.7-1.0-1.01.00.51.1-0.90.9-1.20.2-1.2
Bone: trabecular tissue density1.62.86.82.62.5-2.5-2.0-2.01.1-1.71.1-1.2-0.8-1.30.2-0.4
Water consumed over 24 hours0.71.43.1-1.2-1.31.31.41.3-1.8-0.1-1.61.3-0.61.3-0.20.8
Number of responses in last shaping day0.20.30.70.2-0.10.10.10.1-0.8-0.7-0.60.6-0.80.4-0.70.4